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MATSUMOTO Shigekiyo  松本 重清

ORCIDConnect your ORCID iD *help
Researcher Number 90274761
Other IDs
Affiliation (Current) 2022: 大分大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2011 – 2022: 大分大学, 医学部, 准教授
2010: 大分大学, 医学部, 講師
2008 – 2009: 大分大学, 医学部, 助教
2005: 大分大学, 医学部, 助手
2004: 大分大学, 脳・神経機能統御講座, 助手
2003: Oita University, Faculty of Medicine, Assistant Professor, 医学部, 助手
2002: 大分医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Anesthesiology/Resuscitation studies / Anesthesiology / Basic Section 55050:Anesthesiology-related
Except Principal Investigator
Basic Section 55050:Anesthesiology-related / Basic Section 55060:Emergency medicine-related / Anesthesiology / Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies
Keywords
Principal Investigator
酸化ストレス / ビタミンC / アスコルビン酸 / 敗血症 / 電子スピン共鳴 / フリーラジカル / 脳虚血 / 弓部大動脈置換術 / 脳分離体外循環 / アスコルビン酸ラジカル … More / 電子スピン共鳴法 / ヒドロキシルラジカル / 副腎不全 / ETS-GS / ビタミン / 下垂体後葉ホルモン / 副腎髄質ホルモン / 副腎皮質ホルモン / カテコラミン / コルチゾール / SMP30/GNLノックアウトマウス / 敗血症性ショック / 下垂体ホルモン / 副腎皮質・髄質ホルモン / 下垂体・副腎ホルモン / 副腎機能 / 術後せん妄 / 全身性炎症反応 / 炎症反応 / 周術期せん妄 / 術後認知機能障害 / 抗酸化療法 / 揮発性有機化合物 / 術中バイオマーカー / 急性腎傷害 / 臓器傷害 / 術後合併症 / 呼気モニタリング / 周術期臓器傷害 / 炎症 … More
Except Principal Investigator
フリーラジカル / 電子スピン共鳴 / 抗酸化作用 / ラジカル消去能 / 酸化ストレス / RT-PCR / 局所麻酔薬 / 電子スピン共鳴法 / 質量分析イメージング / 抗酸化能 / スピン共鳴解析 / 核磁気共鳴法 / ビタミンC / 周術期合併症 / 全脳虚血 / 脳低体温療法 / 気腹 / 循環動態 / ADH / Pnumoperitoneum / hemodynamics / local anesthetics / フリーラジカル消去作用 / 水溶性αリポ酸誘導体 / 高エネルギーリン酸 / NMRメタボロミクス / フリーラジカル消去能 / Dexmedetomidine / 虚血再灌流傷害 / スピン解析 / 虚血-再灌流負荷 / 脳エネルギー代謝 / レミフェンタニル / ラジカル消去作用 / remifentanil / 術後認知機能障害 / μオピオイド受容体作動薬 / VCR/DMSO / 外傷 / 電子スピン共鳴装置 / ラジカル / 補充療法 / 敗血症 / 光療法 / 概日リズム / 認知機能障害 / 認知機能傷害 / スピンメタボロミクス / NMR / ESR / 局所麻酔 / 抗酸化 / 酸化増強 / 心停止後症候群 / 治療介入 / 心停止 / 抗酸化物質 / レミマゾラム Less
  • Research Projects

    (16 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (17 People)
  •  Anti-oxidative activity of Remimazolam

    • Principal Investigator
      徳丸 治
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Oita University
  •  Light elicited circadian re-entrainment as a treatment for post-sepsis cognitive impairment

    • Principal Investigator
      小山 淑正
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Oita University
  •  周術期合併症に関する予測因子の基礎的検討-スピンメタボロミクスの臨床応用

    • Principal Investigator
      新宮 千尋
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Oita University
  •  Real-time monitoring of breath volatile organic compounds for early detection of perioperative organ injuryPrincipal Investigator

    • Principal Investigator
      松本 重清
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Oita University
  •  Are local anesthetics antioxidants or prooxidants?

    • Principal Investigator
      北野 敬明
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Oita University
  •  Assessment of oxidative stress and therapeutic intervention in cases of cardiac arrest and Post-Cardiac Arrest Syndrome

    • Principal Investigator
      重光 修
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Oita University
  •  Antioxidative activity of remifentanil: Does remifentanil directly scavenge free radicals?

    • Principal Investigator
      徳丸 治
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Oita University
  •  Establishment of additional Vitamin C therapy for the suppression of oxidative stress from patients with severe traumatic injury

    • Principal Investigator
      竹中 隆一
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Oita University
  •  Antioxidative effect of dexmedetomidine by spin resonance analysis

    • Principal Investigator
      Kitano Takaaki
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology
    • Research Institution
      Oita University
  •  Antioxidative therapy for prevention of postoperative delirium and cognitive dysfunctionPrincipal Investigator

    • Principal Investigator
      Matsumoto Shigekiyo
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology
    • Research Institution
      Oita University
  •  Antioxidative and neuroprotective activity of alpha-lipoic acid derivatives: spin resonance analyses

    • Principal Investigator
      Tokumaru Osamu
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology
    • Research Institution
      Oita University
  •  A new endocrinological mechanism of septic shock and vitamin C supplementation in septic shock under real-time vitamin C monitoring with electron spin resonance spectroscopyPrincipal Investigator

    • Principal Investigator
      Matsumoto Shigekiyo
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology
    • Research Institution
      Oita University
  •  A new strategy for adrenal insufficiency in septic shock: a new antioxdant ETS-GSPrincipal Investigator

    • Principal Investigator
      MATSUMOTO Shigekiyo
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Oita University
  •  Assessing the severity of patients in therapeutic hypothermia for brain -ESR study-

    • Principal Investigator
      SHINGU Chihiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Oita University
  •  血中フリーラジカルの経時的変化による脳虚血の検出:電子スピン共鳴法を用いた検討Principal Investigator

    • Principal Investigator
      松本 重清
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Oita University
      大分医科大学
  •  Effect of. local anesthetics on cerebral and abdominal organ injury during pneumoperitoneum

    • Principal Investigator
      YOSHITAKE Shigenori
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Oita University (Faculty of Medicine)

All 2022 2021 2020 2019 2017 2016 2010

All Journal Article Presentation

  • [Journal Article] Direct free radical scavenging effects of water-soluble HMG-CoA reductase inhibitors2019

    • Author(s)
      Umeda Ryohei、Takanari Hiroki、Ogata Kazue、Matsumoto Shigekiyo、Kitano Takaaki、Ono Katsushige、Tokumaru Osamu
    • Journal Title

      J. Clin. Biochem. Nutr.

      Volume: 64 Issue: 1 Pages: 20-26

    • DOI

      10.3164/jcbn.18-48

    • NAID

      130007542260

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11087, KAKENHI-PROJECT-16H05238, KAKENHI-PROJECT-15K10515, KAKENHI-PROJECT-16K09964, KAKENHI-PROJECT-19H04443
  • [Journal Article] The impact of oxidative stress levels on the clinical effectiveness of sivelestat in treating acute lung injury : an electron spin study.2010

    • Author(s)
      Matsumoto S, Shingu C, Koga H, Hidaka S, Goto K, Hagiwara S, Iwasaka H, Noguchi T, Yokoi I.
    • Journal Title

      Journal of Trauma 68

      Pages: 796-801

    • Data Source
      KAKENHI-PROJECT-20591808
  • [Journal Article] An Electron Spin Resonance Study for Real-time Detection of Ascorbyl Free Radicals After Addition of Dimethyl Sulfoxide in Murine Hippocampus or Plasma During Kainic Acid-Induced Seizures.2010

    • Author(s)
      Matsumoto S, Shingu C, Koga H, Hagiwara S, Iwasaka H, Noguchi T, Yokoi I.
    • Journal Title

      Neurochem Res. 35(7)

      Pages: 1010-1016

    • Data Source
      KAKENHI-PROJECT-20591808
  • [Journal Article] The impact of oxidative stress levels on the clinical effectiveness of sivelestat in treating acute lung injury : an electron spin resonance study2010

    • Author(s)
      Matsumoto S, Shingu C, Koga H, Hidaka S, Goto K, Hagiwara S, Iwasaka H, Noguchi T, Yokoi I.
    • Journal Title

      Journal of Trauma 68

      Pages: 796-801

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591808
  • [Journal Article] An Electron Spin Resonance Study for Real-time Detection of Ascorbyl Free Radicals After Addition of Dimethyl Sulfoxide in Murine Hippocampus or Plasma During Kainic Acid-Induced Seizures2010

    • Author(s)
      Matsumoto S, Shingu C, Koga H, Hagiwara S, Iwasaka H, Noguchi T, Yokoi I
    • Journal Title

      Neurochemical Research (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591808
  • [Presentation] 待機的心臓・大血管手術における術後譫妄と炎症および酸化ストレスの関連ー新規予防戦略の提案ー2022

    • Author(s)
      栗林由英,松本重清,小山淑正,日高正剛,新宮千尋,北野敬明
    • Organizer
      日本麻酔科学会第69回学術集会
    • Data Source
      KAKENHI-PROJECT-17K11088
  • [Presentation] 待機的心臓・大血管手術における高齢者術後譫妄には酸化ストレスが関与するー電子スピン共鳴(ESR)装置を用いた検討ー2021

    • Author(s)
      栗林由英、松本重清、小山淑正、北野敬明
    • Organizer
      第33回日本老年麻酔学会
    • Data Source
      KAKENHI-PROJECT-17K11088
  • [Presentation] Antioxidative activity of ketamineas a direct radical scavenger2021

    • Author(s)
      Tokumaru O, Ozaki Y, Kawano T, Ogata K, Eshima N, Matsumoto S, Kitano T
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19K09329
  • [Presentation] 心臓・大血管疾患に対する待機的手術における術後譫妄とビタミンCの関連ー電子スピン共鳴装置を用いた検討ー2021

    • Author(s)
      栗林由英、松本重清、小山淑正、新宮千尋、尾方和枝、北野敬明
    • Organizer
      日本麻酔科学会第68回学術集会
    • Data Source
      KAKENHI-PROJECT-17K11088
  • [Presentation] Serum Vitamin C Levels were decreased in Severe Emergency Patients2020

    • Author(s)
      ①Ryuichi Takenaka、Nureki Shinichi、Kiyoshige Matsumoto、Osamu Shigemitsu
    • Organizer
      40th ISICEM(国際救急集中治療会議)/Web発表
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09290
  • [Presentation] 電子スピン共鳴法によるデクスメデトミジンのフリーラジカル消去能の検討2019

    • Author(s)
      西田太一, 徳丸治, 松本重清, 内野哲哉, 新宮千尋, 北野敬明
    • Organizer
      日本麻酔科学会
    • Data Source
      KAKENHI-PROJECT-17K11087
  • [Presentation] Antioxidative activity of dexmedetomidine as a direct free radical scavenger2019

    • Author(s)
      Kazue O, Yoshida K, Matsumoto S, Shingu C, Kitano T, Tokumaru O
    • Organizer
      第93回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17K11087
  • [Presentation] Direct observation of ascorbyl free radicals (vitamin C radicals) in blood of perioperative animals2017

    • Author(s)
      Osamu Tokumaru, Shigekiyo Matsumoto, Takayuki Mizoguchi, Takayuki Kawashima, Kazue Ogata, Shinji Miyamoto, Takaaki Kitano
    • Organizer
      第95回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-17K11087
  • [Presentation] Direct observation of ascorbyl free radicals (vitamin C radicals) in blood of perioperative animals2017

    • Author(s)
      Osamu Tokumaru, Shigekiyo Matsumoto, Takayuki Mizoguchi, Takayuki Kawashima, Kazue Ogata, Shinji Miyamoto, Takaaki Kitano
    • Organizer
      第95回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-15K10515
  • [Presentation] 周術期の血液から検出されるアスコルビン酸フリーラジカルについて2016

    • Author(s)
      徳丸治,松本重清,岡本啓太郎,溝口貴之,尾方和枝.北野敬明
    • Organizer
      第69回日本酸化ストレス学会学術集会
    • Place of Presentation
      仙台国際センター会議棟(宮城県・仙台市)
    • Year and Date
      2016-08-30
    • Data Source
      KAKENHI-PROJECT-15K10515
  • 1.  Tokumaru Osamu (40360151)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 7 results
  • 2.  SHINGU Chihiro (30295191)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 6 results
  • 3.  Kitano Takaaki (20211196)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 7 results
  • 4.  江島 伸興 (20203630)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 5.  竹中 隆一 (90457606)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 6.  重光 修 (40215968)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  YOKOI Isao (80150366)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 8.  NOGUCHI Takayuki (90156183)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 9.  YOSHITAKE Shigenori (10200974)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  西田 育弘 (90172668)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  小山 淑正 (40468012)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  穴井 博文 (20291544)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  李 丞祐 (60326460)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KOGA Hironori
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  ISHIGAMI Akihito
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  高成 広起
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  緒方 藍歌
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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