MATSUMOTO Shigekiyo 松本重清

Researcher Number	90274761
Other IDs
Affiliation (Current)	2021: 大分大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2011 – 2020: 大分大学, 医学部, 准教授 2010: 大分大学, 医学部, 講師 2008 – 2009: 大分大学, 医学部, 助教 2005: 大分大学, 医学部, 助手 2004: 大分大学, 脳・神経機能統御講座, 助手 2003: Oita University, Faculty of Medicine, Assistant Professor, 医学部, 助手 2002: 大分医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology / Basic Section 55050:Anesthesiology-related Except Principal Investigator Basic Section 55060:Emergency medicine-related / Basic Section 55050:Anesthesiology-related / Anesthesiology / Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies
Keywords	Principal Investigator 酸化ストレス / ビタミンC / アスコルビン酸 / 敗血症 / 電子スピン共鳴 / フリーラジカル / 脳虚血 / 弓部大動脈置換術 / 脳分離体外循環 / アスコルビン酸ラジカル … More Except Principal Investigator フリーラジカル / 電子スピン共鳴 / 抗酸化作用 / RT-PCR / 電子スピン共鳴法 / 質量分析イメージング / 抗酸化能 / スピン共鳴解析 / 核磁気共鳴法 / ラジカル消去能 / 酸化ストレス / ビタミンC / 全脳虚血 / 脳低体温療法 / 気腹 / 循環動態 / 局所麻酔薬 / ADH / Pnumoperitoneum / hemodynamics / local anesthetics / フリーラジカル消去作用 / 水溶性αリポ酸誘導体 / 高エネルギーリン酸 / NMRメタボロミクス / フリーラジカル消去能 / Dexmedetomidine / 虚血再灌流傷害 / スピン解析 / 虚血-再灌流負荷 / 脳エネルギー代謝 / 敗血症 / 光療法 / 概日リズム / 認知機能傷害 / スピンメタボロミクス / 周術期合併症 / NMR / ESR / 局所麻酔 / 抗酸化 / 酸化増強 / 心停止 / 心停止後症候群 / 抗酸化物質 / remifentanil / ラジカル消去作用 / 術後認知機能障害 / μオピオイド受容体作動薬 / VCR/DMSO / 外傷 / 電子スピン共鳴装置 / ラジカル / 補充療法 Less

Light elicited circadian re-entrainment as a treatment for post-sepsis cognitive impairmentOngoing
- Principal Investigator
  
  小山淑正
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Oita University
周術期合併症に関する予測因子の基礎的検討-スピンメタボロミクスの臨床応用Ongoing
- Principal Investigator
  
  新宮千尋
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Oita University
Real-time monitoring of breath volatile organic compounds for early detection of perioperative organ injuryPrincipal InvestigatorOngoing
- Principal Investigator
  
  松本重清
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Oita University
Are local anesthetics antioxidants or prooxidants?Ongoing
- Principal Investigator
  
  北野敬明
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Oita University
Assessment of oxidative stress and therapeutic intervention in cases of cardiac arrest and Post-Cardiac Arrest SyndromeOngoing
- Principal Investigator
  
  重光修
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Oita University
Antioxidative activity of remifentanil: Does remifentanil directly scavenge free radicals?Ongoing
- Principal Investigator
  
  徳丸治
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Oita University
Establishment of additional Vitamin C therapy for the suppression of oxidative stress from patients with severe traumatic injuryOngoing
- Principal Investigator
  
  竹中隆一
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Oita University
Antioxidative effect of dexmedetomidine by spin resonance analysisOngoing
- Principal Investigator
  
  北野敬明
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Oita University
Antioxidative therapy for prevention of postoperative delirium and cognitive dysfunctionPrincipal InvestigatorOngoing
- Principal Investigator
  
  松本重清
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Oita University
Antioxidative and neuroprotective activity of alpha-lipoic acid derivatives: spin resonance analyses
- Principal Investigator
  
  Tokumaru Osamu
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Oita University
A new endocrinological mechanism of septic shock and vitamin C supplementation in septic shock under real-time vitamin C monitoring with electron spin resonance spectroscopyPrincipal Investigator
- Principal Investigator
  
  Matsumoto Shigekiyo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Oita University
A new strategy for adrenal insufficiency in septic shock: a new antioxdant ETS-GSPrincipal Investigator
- Principal Investigator
  
  MATSUMOTO Shigekiyo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Oita University
Assessing the severity of patients in therapeutic hypothermia for brain -ESR study-
- Principal Investigator
  
  SHINGU Chihiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Oita University
血中フリーラジカルの経時的変化による脳虚血の検出:電子スピン共鳴法を用いた検討Principal Investigator
- Principal Investigator
  
  松本重清
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Oita University
  大分医科大学
Effect of. local anesthetics on cerebral and abdominal organ injury during pneumoperitoneum
- Principal Investigator
  
  YOSHITAKE Shigenori
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Oita University (Faculty of Medicine)

All 2019 2017 2016 2010

All Journal Article Presentation

[Journal Article] Direct free radical scavenging effects of water-soluble HMG-CoA reductase inhibitors2019
- Author(s)
  Umeda Ryohei、Takanari Hiroki、Ogata Kazue、Matsumoto Shigekiyo、Kitano Takaaki、Ono Katsushige、Tokumaru Osamu
- Journal Title
  
  J. Clin. Biochem. Nutr.
  
  Volume: 64 Issue: 1 Pages: 20-26
- DOI
  10.3164/jcbn.18-48
- NAID
  130007542260
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11087, KAKENHI-PROJECT-16H05238, KAKENHI-PROJECT-15K10515, KAKENHI-PROJECT-16K09964
[Journal Article] The impact of oxidative stress levels on the clinical effectiveness of sivelestat in treating acute lung injury : an electron spin study.2010
- Author(s)
  Matsumoto S, Shingu C, Koga H, Hidaka S, Goto K, Hagiwara S, Iwasaka H, Noguchi T, Yokoi I.
- Journal Title
  
  Journal of Trauma 68
  
  Pages: 796-801
- Data Source
  KAKENHI-PROJECT-20591808
[Journal Article] An Electron Spin Resonance Study for Real-time Detection of Ascorbyl Free Radicals After Addition of Dimethyl Sulfoxide in Murine Hippocampus or Plasma During Kainic Acid-Induced Seizures.2010
- Author(s)
  Matsumoto S, Shingu C, Koga H, Hagiwara S, Iwasaka H, Noguchi T, Yokoi I.
- Journal Title
  
  Neurochem Res. 35(7)
  
  Pages: 1010-1016
- Data Source
  KAKENHI-PROJECT-20591808
[Journal Article] The impact of oxidative stress levels on the clinical effectiveness of sivelestat in treating acute lung injury : an electron spin resonance study2010
- Author(s)
  Matsumoto S, Shingu C, Koga H, Hidaka S, Goto K, Hagiwara S, Iwasaka H, Noguchi T, Yokoi I.
- Journal Title
  
  Journal of Trauma 68
  
  Pages: 796-801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591808
[Journal Article] An Electron Spin Resonance Study for Real-time Detection of Ascorbyl Free Radicals After Addition of Dimethyl Sulfoxide in Murine Hippocampus or Plasma During Kainic Acid-Induced Seizures2010
- Author(s)
  Matsumoto S, Shingu C, Koga H, Hagiwara S, Iwasaka H, Noguchi T, Yokoi I
- Journal Title
  
  Neurochemical Research (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591808
[Presentation] 電子スピン共鳴法によるデクスメデトミジンのフリーラジカル消去能の検討2019
- Author(s)
  西田太一, 徳丸治, 松本重清, 内野哲哉, 新宮千尋, 北野敬明
- Organizer
  日本麻酔科学会
- Data Source
  KAKENHI-PROJECT-17K11087
[Presentation] Antioxidative activity of dexmedetomidine as a direct free radical scavenger2019
- Author(s)
  Kazue O, Yoshida K, Matsumoto S, Shingu C, Kitano T, Tokumaru O
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K11087
[Presentation] Direct observation of ascorbyl free radicals (vitamin C radicals) in blood of perioperative animals2017
- Author(s)
  Osamu Tokumaru, Shigekiyo Matsumoto, Takayuki Mizoguchi, Takayuki Kawashima, Kazue Ogata, Shinji Miyamoto, Takaaki Kitano
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K11087
[Presentation] Direct observation of ascorbyl free radicals (vitamin C radicals) in blood of perioperative animals2017
- Author(s)
  Osamu Tokumaru, Shigekiyo Matsumoto, Takayuki Mizoguchi, Takayuki Kawashima, Kazue Ogata, Shinji Miyamoto, Takaaki Kitano
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-15K10515
[Presentation] 周術期の血液から検出されるアスコルビン酸フリーラジカルについて2016
- Author(s)
  徳丸治，松本重清，岡本啓太郎，溝口貴之，尾方和枝．北野敬明
- Organizer
  第69回日本酸化ストレス学会学術集会
- Place of Presentation
  仙台国際センター会議棟（宮城県・仙台市）
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-15K10515

1. Tokumaru Osamu (40360151)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
2. SHINGU Chihiro (30295191)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
3. 北野敬明 (20211196)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
4. 江島伸興 (20203630)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 重光修 (40215968)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 竹中隆一 (90457606)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. YOKOI Isao (80150366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. NOGUCHI Takayuki (90156183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. YOSHITAKE Shigenori (10200974)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 西田育弘 (90172668)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 小山淑正 (40468012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 穴井博文 (20291544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 李丞祐 (60326460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KOGA Hironori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. ISHIGAMI Akihito

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 高成広起

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 緒方藍歌

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MATSUMOTO Shigekiyo 松本 重清

Research Projects

Research Products

Co-Researchers

Light elicited circadian re-entrainment as a treatment for post-sepsis cognitive impairmentOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

周術期合併症に関する予測因子の基礎的検討-スピンメタボロミクスの臨床応用Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Real-time monitoring of breath volatile organic compounds for early detection of perioperative organ injuryPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Are local anesthetics antioxidants or prooxidants?Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Assessment of oxidative stress and therapeutic intervention in cases of cardiac arrest and Post-Cardiac Arrest SyndromeOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Antioxidative activity of remifentanil: Does remifentanil directly scavenge free radicals?Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of additional Vitamin C therapy for the suppression of oxidative stress from patients with severe traumatic injuryOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Antioxidative effect of dexmedetomidine by spin resonance analysisOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Antioxidative therapy for prevention of postoperative delirium and cognitive dysfunctionPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Antioxidative and neuroprotective activity of alpha-lipoic acid derivatives: spin resonance analyses

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A new endocrinological mechanism of septic shock and vitamin C supplementation in septic shock under real-time vitamin C monitoring with electron spin resonance spectroscopyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A new strategy for adrenal insufficiency in septic shock: a new antioxdant ETS-GSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Assessing the severity of patients in therapeutic hypothermia for brain -ESR study-

Principal Investigator

Project Period (FY)

Research Category

MATSUMOTO Shigekiyo 松本重清