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Shiokawa Daisuke  塩川 大介

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… Alternative Names

DAISUKE Shiokaswa  塩川 大介

SHIOKAWA Daisuke  塩川 大介

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Researcher Number 90277278
Other IDs
Affiliation (Current) 2026: 愛媛大学, 医学部附属病院, 准教授
Affiliation (based on the past Project Information) *help 2024: 愛媛大学, 医学部附属病院, 准教授
2023 – 2024: 愛媛大学, 医学部附属病院, 講師
2022: 国立研究開発法人国立がん研究センター, 研究所, ユニット長
2018 – 2020: 国立研究開発法人国立がん研究センター, 研究所, ユニット長
2015: 国立研究開発法人国立がん研究センター, がん分化制御解析分野, ユニット長 … More
2015: 国立研究開発法人国立がん研究センター, その他部局等, ユニット長
2014: 独立行政法人国立がん研究センター, がん分化制御解析分野, ユニット長
1998 – 2006: 東京理科大学, 薬学部, 助手
1996: Science University of Tokyo, Assistant Professor, 薬学部, 助手 Less
Review Section/Research Field
Principal Investigator
Basic Section 49030:Experimental pathology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / 細胞死(アポトーシス) / Experimental pathology / Biological pharmacy / Molecular biology
Except Principal Investigator
Biological Sciences / Biological pharmacy / Cell biology
Keywords
Principal Investigator
シングルセル / 大腸がん / Wntシグナル / 遺伝子発現解析 / apoptosis / エンドヌクレアーゼ / DNase / アポトーシス / 共培養 / がん微小環境 … More / 浸潤先端細胞 / がん転移 / 空間トランスクリプトミクス / 細胞不均一性 / 細胞多様性 / がん幹細胞 / neuron / endonuclease / expression / gene / differentiation / 転写調節 / 神経 / 遺伝子発現 / 細胞分化 / translation initiation / GPI-anchor / interferon / phagocytosis / macrophage / 細胞死 / DNase γ / GFP / 核移行シグナル / 細胞内局在 … More
Except Principal Investigator
アポトーシス / DNaseγ / DNase γ / class switch / apoptosis / クラススイッチ / クローナルデリーション / ネガティブセレクション / ノックアウトマウス / DNase gamma / 胸腺細胞 / モノクローナル抗体 / DNA断片化 / DNA修復 / self antigen / disease / autoimmune / knockout mice / 自己抗体 / 自己免疫疾患 / clonal deletion / negative selection / knockout mouse / 相同組換え / ES細胞 / DNase_γ / cell death / DNA endonuclease / DNA fragmentation / apoptpsis / プログラム細胞死 / ヌクレオソーム / DNA分断化 / ネクローシス / 細胞死 / エンドヌクレアーゼ / 細胞縮小 / ドラッグデザイン / カスパーゼ / Smac / IAP / がん / B細胞 / Caspase / 細胞増殖 / 細胞分化 / ヒト卵巣癌細胞 / 制癌剤 / X線 / 核移行シグナル / ポリ(ADP-リボシル)化 Less
  • Research Projects

    (15 results)
  • Research Products

    (36 results)
  • Co-Researchers

    (11 People)
  •  Elucidation of the Mechanism by Which the Tumor Microenvironment Induces the Emergence of Invasive and Metastatic Cancer CellsPrincipal Investigator

    • Principal Investigator
      Shiokawa Daisuke
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Ehime University
      National Cancer Center Japan
  •  Single-cell gene expression analysis reveals the cellular heterogeneity of colon tumors and identifies novel therapeutic target genesPrincipal Investigator

    • Principal Investigator
      Shiokawa Daisuke
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      National Cancer Center Japan
  •  Characterization of cellular heterogeneity of colon tumors by gene expression analyses at the single cell levelPrincipal Investigator

    • Principal Investigator
      Shiokawa Daisuke
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      National Cancer Center Japan
  •  XIAP阻害Smac-mimetic分子設計による制がんリード化合物の創製

    • Principal Investigator
      田沼 靖一
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo University of Science
  •  マクロファージの貧食/アポトーシスにおけるDNA分解機構の解明Principal Investigator

    • Principal Investigator
      塩川 大介
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tokyo University of Science
  •  真核細胞の分化/アポトーシス経路切り換え機構の解明

    • Principal Investigator
      田沼 靖一
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo University of Science
  •  Involvement of DNase g during apoptosis associated with myogenic differentiationPrincipal Investigator

    • Principal Investigator
      SHIOKAWA Daisuke
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      細胞死(アポトーシス)
    • Research Institution
      TOKYO UNIVERSITY OF SCIENCE
  •  Apoptosis in DNase g deficient mic

    • Principal Investigator
      TANUMA Seiichi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      TOKYO UNIVERSITY OF SCIENCE
  •  アポトーシス・DNaseγを標的としたがん診断法の開発

    • Principal Investigator
      田沼 靖一
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo University of Science
  •  アポトーシス、DNaseγを指標としたがん診断法の開発

    • Principal Investigator
      田沼 靖一
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo University of Science
  •  Analysis ofApoptosis Mechanisms in DNase y-deficient Mice

    • Principal Investigator
      SEI-ICHI Tanuma
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Science University of Tokyo
  •  哺乳類細胞のDNA修復とアポトーシスの経路選択機構

    • Principal Investigator
      田沼 靖一
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tokyo University of Science
  •  アポトーシスを司るエンドヌクレアーゼ、DNase_γの活性制御機構Principal Investigator

    • Principal Investigator
      塩川 大介
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Molecular biology
    • Research Institution
      Tokyo University of Science
  •  哺乳類細胞のDNA修復とアポトーシスの経路選択機構

    • Principal Investigator
      TANUMA Sei-ichi
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo University of Science
  •  Molecular mechanisms and function of apoptosis Faculty of Pharmaceutical Science

    • Principal Investigator
      TANUMA Sei-ichi
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      Science University of Tokyo

All 2024 2023 2022 2020 2019 2018 2015 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] 阻害剤・活性化剤ハンドブック (秋山徹、河府和義 編)2019

    • Author(s)
      塩川大介
    • Total Pages
      646
    • Publisher
      羊土社
    • ISBN
      9784758120999
    • Data Source
      KAKENHI-PROJECT-18K07283
  • [Journal Article] Genetic variation in the RETN promoter, accompanied by latent sarcopenic obesity, led to insulin resistance in a Japanese cohort: the Toon Genome Study2024

    • Author(s)
      Ikeda Yosuke、Kawamura Ryoichi、Tabara Yasuharu、Maruyama Koutatsu、Shiokawa Daisuke、Takakado Misaki、Hadate Toshimi、Takata Yasunori、Ohashi Jun、Saito Isao、Ogawa Yoshihiro、Osawa Haruhiko
    • Journal Title

      Diabetologia

      Volume: 68 Issue: 4 Pages: 854-865

    • DOI

      10.1007/s00125-024-06322-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07037, KAKENHI-PROJECT-23K14738
  • [Journal Article] Targeting PDGF signaling of cancer-associated fibroblasts blocks feedback activation of HIF-1α and tumor progression of clear cell ovarian cancer2024

    • Author(s)
      Yutaro Mori、Yoshie Okimoto、Hiroaki Sakai、Yusuke Kanda、Hirokazu Ohata、Daisuke Shiokawa、Mikiko Suzuki、Hiroshi Yoshida、Haruka Ueda、Tomoyuki Sekizuka、Ryo Tamura、Kaoru Yamawaki、Tatsuya Ishiguro、Yasushi Yatabe、Akinobu Hamada、Kosuke Yoshihara、Takayuki Enomoto、Koji Okamoto et al.
    • Journal Title

      Cell Reports Medicine

      Volume: - Issue: 5 Pages: 101532-101532

    • DOI

      10.1016/j.xcrm.2024.101532

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-21K09490, KAKENHI-PROJECT-22K07037, KAKENHI-PROJECT-22K09635, KAKENHI-PROJECT-23K27389, KAKENHI-PROJECT-23K08794, KAKENHI-PROJECT-24K10319, KAKENHI-PROJECT-24K19687
  • [Journal Article] PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway2023

    • Author(s)
      Ohata Hirokazu、Shiokawa Daisuke、Sakai Hiroaki、Kanda Yusuke、Okimoto Yoshie、Kaneko Syuzo、Hamamoto Ryuji、Nakagama Hitoshi、Okamoto Koji
    • Journal Title

      Cell Reports

      Volume: 42 Issue: 6 Pages: 112519-112519

    • DOI

      10.1016/j.celrep.2023.112519

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07037, KAKENHI-PROJECT-23K07467, KAKENHI-PROJECT-21H03081, KAKENHI-PROJECT-21H03550
  • [Journal Article] Elevated stress response marks deeply quiescent reserve cells of gastric chief cells2023

    • Author(s)
      Shiokawa Daisuke、Sakai Hiroaki、Koizumi Miho、Okimoto Yoshie、Mori Yutaro、Kanda Yusuke、Ohata Hirokazu、Honda Hiroaki、Okamoto Koji
    • Journal Title

      Communications Biology

      Volume: 6 Issue: 1 Pages: 1183-1183

    • DOI

      10.1038/s42003-023-05550-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07037, KAKENHI-PROJECT-21H03081, KAKENHI-PROJECT-23K27442
  • [Journal Article] FXYD3 functionally demarcates an ancestral breast cancer stem cell subpopulation with features of drug-tolerant persisters2023

    • Author(s)
      Li Mengjiao、Nishimura Tatsunori、Takeuchi Yasuto、Hongu Tsunaki、Wang Yuming、Hirose Haruka、Nomura Seitaro、Suzuki Yutaka、Okamoto Koji、Gotoh Noriko (et al. 22)
    • Journal Title

      Journal of Clinical Investigation

      Volume: 133 Issue: 22 Pages: 1-19

    • DOI

      10.1172/jci166666

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18237, KAKENHI-PROJECT-21K15501, KAKENHI-PROJECT-22K07037, KAKENHI-PROJECT-23K06610, KAKENHI-PROJECT-23K06630, KAKENHI-PROJECT-22K20818, KAKENHI-PLANNED-23H04938, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-21H02761, KAKENHI-PROJECT-21H03081, KAKENHI-PROJECT-22H00471
  • [Journal Article] Stemness and immune evasion conferred by TDO2-AHR pathway are associated with liver metastasis of colon cancer.2022

    • Author(s)
      Miyazaki T, Chung S, Sakai H, Ohata H, Obata Y, Shiokawa D, Mizoguchi Y, Kubo T, Ichikawa H, Taniguchi H, Aoki K, Soga T, Nakagama H, *Okamoto K.
    • Journal Title

      Cancer Sci.

      Volume: 113 Issue: 1 Pages: 170-181

    • DOI

      10.1111/cas.15182

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03081, KAKENHI-PROJECT-20K09023, KAKENHI-PROJECT-21K07163, KAKENHI-PROJECT-22K07037
  • [Journal Article] NF-κB suppression synergizes with E7386, an inhibitor of CBP/β-catenin interaction, to block proliferation of patient-derived colon cancer spheroids.2022

    • Author(s)
      Kanda Y, Ohata H, Miyazaki T, Sakai H, Mori Y, Shiokawa D, Yokoi A, Owa T, Ochiai A, *Okamoto K.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 586 Pages: 93-99

    • DOI

      10.1016/j.bbrc.2021.11.063

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H03081, KAKENHI-PROJECT-20K09023, KAKENHI-PROJECT-20K16230, KAKENHI-PROJECT-22K07037
  • [Journal Article] Slow-Cycling Cancer Stem Cells Regulate Progression and Chemoresistance in Colon Cancer2020

    • Author(s)
      Shiokawa Daisuke、Sakai Hiroaki、Ohata Hirokazu、Miyazaki Toshiaki、Kanda Yusuke、Sekine Shigeki、Narushima Daichi、Hosokawa Masahito、Kato Mamoru、Suzuki Yutaka、Takeyama Haruko、Kambara Hideki、Nakagama Hitoshi、Okamoto Koji
    • Journal Title

      Cancer Research

      Volume: 80 Issue: 20 Pages: 4451-4464

    • DOI

      10.1158/0008-5472.can-20-0378

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K09023, KAKENHI-PROJECT-20K16230, KAKENHI-PROJECT-18K07283
  • [Journal Article] NOX1-dependent mTORC1 activation via S100A9 oxidation in cancer stem-like cells leads to colon cancer progression.2019

    • Author(s)
      Ohata H, Shiokawa D, Obata Y, Sato A, Sakai H, Fukami M, Hara W, Taniguchi H, Ono M, Nakagama H, Okamoto K.
    • Journal Title

      Cell Rep.

      Volume: 28 Issue: 5 Pages: 1282-1295

    • DOI

      10.1016/j.celrep.2019.06.085

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07208, KAKENHI-PROJECT-18K07283, KAKENHI-PROJECT-19H03722
  • [Journal Article] DNase X is a GPI-anchored membrane enzyme that provides a barrier to endocytosis-mediated transfer of a foreign gene2007

    • Author(s)
      Shiokawa D. et al.
    • Journal Title

      J Biol Chem (In press)

    • Data Source
      KAKENHI-PROJECT-17790075
  • [Journal Article] Stage-specific expression of DNasegamma during B-cell development and its role in B-cell receptor-mediated apoptosis in WEHI-231 cells2007

    • Author(s)
      Shiokawa D. et al.
    • Journal Title

      Cell Death Differ 14

      Pages: 992-1000

    • Data Source
      KAKENHI-PROJECT-17790075
  • [Journal Article] cDNA cloning and functional characterization of Xenopus laevis DNase gamma.2006

    • Author(s)
      Shiokawa, D. et al.
    • Journal Title

      Apoptosis In press

    • Data Source
      KAKENHI-PROJECT-17790075
  • [Journal Article] cDNA cloning and functional characterization of Xenopus laevis DNase gamma2006

    • Author(s)
      Shiokawa D. et al.
    • Journal Title

      Apoptosis 11

      Pages: 555-562

    • Data Source
      KAKENHI-PROJECT-17790075
  • [Journal Article] Physical and biochemical properties of mammalian DNase X proteins : non-AUG translation initiation of porcine and bovine mRNAs for DNase X2005

    • Author(s)
      Shiokawa, D. et al.
    • Journal Title

      Biochem J 329

      Pages: 511-517

    • Data Source
      KAKENHI-PROJECT-17790075
  • [Journal Article] Involvement of DNase gamma in the resected double-strand DNA breaks in immunogbulin genes.2005

    • Author(s)
      Daisuke Shiokawa
    • Journal Title

      Biochem Biophys Res Commun. 327

      Pages: 76-83

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15603006
  • [Journal Article] Characterization of the human DNAS1L2 gene and the molecular mechanism for its transcriptional activation induced by inflammatory cytokines.2004

    • Author(s)
      Daisuke Shiokawa
    • Journal Title

      Genomics. 84

      Pages: 95-105

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15603006
  • [Journal Article] A novel inhibitor that protects apoptotic DNA fragmentation catalyzed by DNase gamma.2004

    • Author(s)
      Daisuke Shiokawa
    • Journal Title

      Biochem Biophys Res Commun. 325

      Pages: 1292-1297

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15603006
  • [Journal Article] Differential DNases are selectively used in neuronal apoptosis depending on the differentiation state.2004

    • Author(s)
      Daisuke Shiokawa
    • Journal Title

      Cell Death Differ. 11

      Pages: 1112-1120

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15603006
  • [Journal Article] Expression of DNase gamma during Fas-independent apoptotic DNA fragmentation in rodent hepatocytes.2004

    • Author(s)
      Daisuke Shiokawa
    • Journal Title

      Cell Tissue Res. 316

      Pages: 403-407

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15603006
  • [Journal Article] Characterization of the human DNA S1L2 gene and the molecular mechanism for its transcriptional activation induced by inflammatory cytokines.2004

    • Author(s)
      Daisuke Shiokawa
    • Journal Title

      Genomics. 84

      Pages: 95-105

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15603006
  • [Journal Article] Aging increases DNase gamma, an apoptosis-related endonuclease, in rat liver nuclei : effect of dietary restriction.2004

    • Author(s)
      Daisuke Shiokawa
    • Journal Title

      Exp Gerontol. 39

      Pages: 195-202

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15603006
  • [Presentation] 肝臓がんにおけるPHLDA familyの機能解析2023

    • Author(s)
      小林直矢、青木清乃、チンヨ、山本雅大 、塩川大介、大木理恵子
    • Organizer
      日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22K07037
  • [Presentation] Development of colon cancer invasion front cells via interaction with tumor microenvironment2023

    • Author(s)
      Daisuke Shiokawa, Hirokazu Ohata, and Koji Okamoto
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-22K07037
  • [Presentation] Reverse-Phase Protein Array for Proteo-Epigenomic Profiling of Colorectal Cancer Patient-Derived Organoids2023

    • Author(s)
      Shota Takeda, Daisuke Shiokawa, Toru Aoyama, Kenichi Yoshioka, Koji Okamoto, Mari Masuda
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-22K07037
  • [Presentation] Elucidation of chemoresistant niches of ovarian clear cell carcinoma via single-cell analyses & spatial transcriptomics2022

    • Author(s)
      森 裕太郎、神田 裕介、石黒 竜也、吉原 弘祐、山脇 芳、大畑 広和、塩川 大介、榎本 隆之、岡本 康司
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K07037
  • [Presentation] FXYD3, a subunit of Na+K+ pump, determines the root of triple-negative breast cancer stem-like cells2022

    • Author(s)
      李 梦嬌、西村 建徳、塩川 大介、矢野 正雄、石川 聡子、太田 哲生 、田辺 真彦 、多田 敬一郎、秋山 徹、島村 徹平、佐藤 慎哉、宮城 洋平、鈴木 穣、岡本 康司、東條 有伸、後藤 典子
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K07037
  • [Presentation] A gene expression signature in slow-cycling colon cancer stem cells: Implications for cancer progression and chemoresistance2022

    • Author(s)
      DAISUKE SHIOKAWA, HIROAKI SAKAI, HIROKAZU OHATA, YUSUKE KANDA, HITOSHI NAKAGAMA, KOJI OKAMOTO
    • Organizer
      12th AACR-JCA Joint Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07037
  • [Presentation] PROX1 induction by autophagy provide a persister-like state via repression of NOX1-mTORC1 pathway in colon cancer cells2022

    • Author(s)
      大畑 広和、塩川 大介、岡本 康司
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K07037
  • [Presentation] Transcriptional factor Tcf1 controls the drug resistance of Lgr5-positive colon tumor stem cells2019

    • Author(s)
      Daisuke Shiokawa, Hirokazu Ohata, Koji Okamoto
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K07283
  • [Presentation] The slow-growing sub-population of Lgr5-positive colon tumor stem cells is resistant to an anti-cancer drug treatment2018

    • Author(s)
      Daisuke Shiokawa
    • Organizer
      日本癌学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07283
  • [Presentation] Heterogeneity of Lgr5-positive colon tumor stem cells demonstrated by single-cell qPCR2015

    • Author(s)
      Daisuke Shiokawa, Hirokazu Ohata, Koji Okamoto
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26670195
  • [Presentation] Dynamic regulation of colon tumor-derived stem cells demonstrated by single-cell qPCR2015

    • Author(s)
      Daisuke Shiokawa, Hirokazu Ohata, Koji Okamoto
    • Organizer
      幹細胞シンポジウム
    • Place of Presentation
      東京大学 伊藤国際学術研究センターB2F 伊藤謝恩ホール
    • Year and Date
      2015-05-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670195
  • [Presentation] ROS enhances stemness by activating mTOR pathway in colorectal cancer stem cells

    • Author(s)
      Hirokazu Ohata, Daisuke Shiokawa, Hitoshi Nakagama, Koji Okamoto
    • Organizer
      日本癌学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26670195
  • [Presentation] Altered expression of a subset of Wnt target genes in colon tumor-derived stem cells demonstrated by single-cell qPCR

    • Author(s)
      Daisuke Shiokawa, Masako Ochiai, Hitoshi Nakagama, Koji Okamoto
    • Organizer
      日本癌学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26670195
  • [Presentation] nterleukin-22 disrupts cell polarity and barrier function in the 3D cultured intestinal epithelial cell

    • Author(s)
      Yoshinori Ikarashi, Junya Asahira, Takuya Matsuyama, Daisuke Shiokawa, Kazuhiro Kato, Toshio Imai, Hitoshi Nakagama, and Koji Okamoto
    • Organizer
      日本癌学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26670195
  • 1.  TANUMA Sei-ichi (10142449)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 2.  MARUTA Hideharu (00266917)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  青木 一正 (10184029)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  内海 文彰 (00256679)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  岡本 康司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 6.  小幡 裕希
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  大畑 広和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  後藤 典子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  鈴木 穣
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  浜田 道昭
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  森 宙史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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