CHIKUMI Hiroki 千酌浩樹

Researcher Number	90283994
Other IDs
Affiliation (Current)	2023: 鳥取大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2021: 鳥取大学, 医学部, 教授 2014 – 2021: 鳥取大学, 医学部附属病院, 教授 2014: 鳥取大学, 医学部付属病院, 教授 2012: 鳥取大学, 医学部付属病院, 准教授 2012: 鳥取大学, 医学部附属病院, 准教授 … More 2009 – 2011: Tottori University, 医学部, 講師 2005 – 2007: Tottori University, Faculty of Medicine, Assistant Professor, 医学部, 講師 2004: 国立大学法人鳥取大学, 医学部, 助手 2003: Tottori Univ., Dept.of Multidisciplinary Internal Medicine, Assistant, 医学部, 助手 1999: Tottori University, Hospital, Assistant, 医学部附属病院, 助手 1998 – 1999: 鳥取大学, 医学部・附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Emergency medicine / Basic Section 58010:Medical management and medical sociology-related / Basic Section 53030:Respiratory medicine-related Except Principal Investigator Respiratory organ internal medicine / Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related
Keywords	Principal Investigator 肺癌 / NK細胞 / ULBP2 / Rho / RhoGEF / PDZ-RhoGEF / p115RhoGEF / LARG / 薬剤反応性 / 内科 … More / 薬剤反応 / 敗血症 / 可溶性ULBP2 / 免疫療法 / RDZ-RhoGEF / Pho / lung cancer / サーベイランス / 薬剤耐性 / AMR / 薬剤耐性菌 / サーベイランスシステム / グローバル / ローカル / COVID-19 … More Except Principal Investigator 睡眠時無呼吸症候群 / 時計遺伝子 / 生理学 / 胸膜中皮腫 / ELISA / 間歇的低酸素 / IL-6 / VEGF / 内科学 / 低酸素 / 分子標的治療 / 概日時計 / 時計被制御遺伝子 / 分子時計 / 気管支喘息 / 睡眠時無呼吸 / 睡眠関連呼吸障害 / 低酸素血症 / 交感神経活動亢進 / 悪性胸膜中皮腫 / ペメトレキセド / 臨床呼吸器学 / 耐性 / 加湿器 / 相対湿度 / 慢性呼吸不全 / 細菌培養 / 細菌汚染 / 酸素濃度 / 中空糸 / humidifier / relative humidity / chronic respiratory failure / bacterial culture / bacterial contamination / oxygen concentration / hollow fiber / 肺癌 / 癌抑制遺伝子 / 抗体 / 健診 / 抗Rb抗体 / 早期発見 / 早期診断 / 癌遺伝子産物抗体 / 網膜芽細胞腫 / 検診 / 癌制遺伝子 / 癌遺伝子 / 血清診断 / lung cancer / tumor suppressor gene / antibody / health examination / 内科 / 遺伝子 / 概日リズム / Physiology / Internal medicine / gene / circadian rhythm / clock gene / sleep apnea syndrome / 腸内細菌叢 / 非結核性抗酸菌症 / メタゲノム解析 Less

COVID-19に対する可溶性ULBP2制御によるNK細胞療法の開発Principal Investigator
- Principal Investigator
  
  千酌浩樹
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tottori University
非結核性抗酸菌症と腸内細菌叢の関わりについて
- Principal Investigator
  
  高田美也子
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tottori University
Development of a novel surveillance system integrating local and global AMR informationPrincipal Investigator
- Principal Investigator
  
  CHIKUMI Hiroki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Tottori University
Development of the new clinical cure to overcome pemetrexed tolerance for malignant pleural mesothelioma
- Principal Investigator
  
  SHIMIZU EIJI
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tottori University
A novel therapy for sepsis by regulating soluble ULBP2Principal Investigator
- Principal Investigator
  
  CHIKUMI HIROKI
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Tottori University
Molecular biological influence of sleep apnea syndrome on circadian clock system
- Principal Investigator
  
  BURIOKA Naoto
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tottori University
Development of novel therapy for malignant mesothelioma by controllingADCC activity.
- Principal Investigator
  
  SHIMIZU Eiji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tottori University
Development of novel biomarker for cetuximab therapy in lung cancerPrincipal Investigator
- Principal Investigator
  
  CHIKUMI Hiroki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tottori University
Influence of sleep apnea syndrome on clock gene dysfunction
- Principal Investigator
  
  BURIOKA Naoto
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tottori University
Clock gene dysfunction in patients with obstructive sleep apnea syndrome
- Principal Investigator
  
  BURIOKA Naoto
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tottori University
Analysis of activation mechanisms of Rho and RhoGEFs as a new molecular target for lung cancer therapy.Principal Investigator
- Principal Investigator
  
  CHIKUMI Hiroki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tottori University
Measurement of antibodies against tumor suppressor gene products in health screening for lung cancer
- Principal Investigator
  
  SHIMIZU Eiji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tottori University Faculty of Medicine
Development and clinical utility of membrane humidifier without need of water for humidification
- Principal Investigator
  
  BURIOKA Naoto
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tottori University

[Journal Article] Clinical characteristics and treatment outcomes of carbapenem-resistant Enterobacterales infections in Japan2022
- Author(s)
  Oka K, Chikumi H, et al.
- Journal Title
  
  J Glob Antimicrob Resist
  
  Volume: 13 Pages: 247-252
- DOI
  10.1016/j.jgar.2022.04.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09972
[Journal Article] Evaluation of infections in orthopedic patients using next-generation sequencing2021
- Author(s)
  Ogawa S, Chikumi H, et al.
- Journal Title
  
  J Infect Chemother
  
  Volume: 27 Issue: 11 Pages: 1626-1633
- DOI
  10.1016/j.jiac.2021.07.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09972
[Journal Article] 緑膿菌耐性率に関連するカルバペネム系抗菌薬の使用評価指標の単施設後方視的調査研究2020
- Author(s)
  三好由希子、高根浩、森下奨太、岡田健作、北浦剛、千酌浩樹
- Journal Title
  
  日本環境感染学会誌
  
  Volume: 35 Pages: 233-240
- NAID
  130008043241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09972
[Journal Article] 抗菌薬適正使用の考え方2020
- Author(s)
  千酌浩樹
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 110 Pages: 526-533
- Data Source
  KAKENHI-PROJECT-18K09972
[Journal Article] γ-Tocotrienol Inhibits TGF-β1-Induced Contractile Phenotype Expression of Human Airway Smooth Muscle Cells.2018
- Author(s)
  Fukushima T, Yamasaki A, Harada T, Chikumi H, Watanabe M, Okazaki R, Takata M, Hasegawa Y, Kurai J, Yanai M, Yamamoto A, Sueda Y, Halayko AJ, Shimizu E.
- Journal Title
  
  Yonago Acta Med.
  
  Volume: 60 Pages: 16-23
- NAID
  120005999117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462755
[Journal Article] Evaluation of antigen‐positive toxin‐negative enzyme immunoassay results for the diagnosis of toxigenic Clostridium difficile infection2018
- Author(s)
  Akamatsu Y, Morishita S, Okamoto R, Okada K, Kitaura T, Miyake N, Yamaguchi K, Nakamoto M, Shimohiro H, Takata M, Yamasaki A, Burioka N, Shimizu E.
- Journal Title
  
  J. Med. Invest.
  
  Volume: 65 Issue: 1.2 Pages: 131-135
- DOI
  10.2152/jmi.65.131
- NAID
  130006575562
- ISSN
  1343-1420, 1349-6867
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461159, KAKENHI-PROJECT-26462755
[Journal Article] Shewanella algae Bacteremia in an End-stage Renal Disease Patient: A Case Report and Review of the Literature2017
- Author(s)
  Takata T, Chikumi H, Morishita S, Hamada S, Hoi S, Iyama T, Fukui T, Matono T, Fukuda S, Munemura C, Isomoto H.
- Journal Title
  
  Intern Med
  
  Volume: 56 Pages: 729-732
- NAID
  130005450344
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462755
[Journal Article] γ-Tocotrienol Inhibits TGF-β1-Induced Contractile Phenotype Expression of Human Airway Smooth Muscle Cells2017
- Author(s)
  Fukushima T, Yamasaki A, Harada T, Chikumi H, Watanabe M, Okazaki R, Takata M, Hasegawa Y, Kurai J, Yanai M, Yamamoto A, Sueda Y, Halayko AJ, Shimizu E.
- Journal Title
  
  Yonago Acta Med
  
  Volume: 60 Pages: 16-23
- NAID
  120005999117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462755
[Journal Article] γ-Tocotrienol Inhibits TGF-β1-Induced Contractile Phenotype Expression of Human Airway Smooth Muscle Cells.2017
- Author(s)
  Fukushima T, Yamasaki A, Harada T, Chikumi H, Watanabe M, Okazaki R, Takata M, Hasegawa Y, Kurai J, Yanai M, Yamamoto A, Sueda Y, Halayko AJ, Shimizu E.
- Journal Title
  
  Yonago Acta Med
  
  Volume: 60 Pages: 16-23
- NAID
  120005999117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] Properties of Achromobacter xylosoxidans highly resistant to aminoglycoside antibiotics.2016
- Author(s)
  Nakamoto S, Goda N, Hayabuchi T, Tamaki H, Ishida A, Suzuki A, Nakano K, Yui S, Katsumata Y, Yamagami Y, Burioka N, Chikumi H, Shimizu E.
- Journal Title
  
  Jpn J Antibiot
  
  Volume: 69 Pages: 113-118
- NAID
  40020827421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462755
[Journal Article] 【Antimicrobial Stewardship Program(ASP)の理論と実際】 ASP推進における医師の役割　患者にとって有効で,かつ耐性菌を過剰に生じさせないためには2016
- Author(s)
  千酌浩樹
- Journal Title
  
  化学療法の領域
  
  Volume: 32 Pages: 1986-1993
- Data Source
  KAKENHI-PROJECT-26462755
[Journal Article] A new rapid method for detecting epidermal growth factor receptor mutations in non-small cell lung cancer2015
- Author(s)
  Takata M, Chikumi H, Matsunami K, Kodani M, Sakamoto T, Hashimoto K, Nakamoto M, Okada K, Kitaura T, Matsumoto S, Kurai J, Yamasaki A, Igishi T, Burioka N, Shimizu E
- Journal Title
  
  Oncol Rep
  
  Volume: 33 Issue: 3 Pages: 1040-1048
- DOI
  10.3892/or.2015.3716
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] Effect of Clarithromycin on the expression of UL16-binding protein 2 in human cells.2015
- Author(s)
  Okada K, Chikumi H, et al.
- Journal Title
  
  Yonago Acta Medica
  
  Volume: 58 Pages: 31-38
- NAID
  120005596728
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462755
[Journal Article] A novel point-of-care system for high-speed real-time polymerase chain reaction testing for epidermal growth factor receptor mutations in bronchial lavage fluids after transbronchial biopsy in patients with non-small cell lung cancer2015
- Author(s)
  Sakamoto T, Kodani M, Takata M, Chikumi H, Nakamoto M, Nishii-Ito S, Ueda Y, Izumi H, Makino H, Touge H, Takeda K, Yamasaki A, Yanai M, Tanaka N, Igishi T, Shimizu E
- Journal Title
  
  Int J Oncol
  
  Volume: 46 Issue: 4 Pages: 1473-1480
- DOI
  10.3892/ijo.2015.2875
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] Lack of AKT activation in lung cancer cells with EGFR mutation is a novel marker of cetuximab sensitivity2012
- Author(s)
  Takata M, Chikumi H, Miyake N, Adachi K, Kanamori Y, Yamasaki A, Igishi T, Burioka N, Nanba E, Shimizu E
- Journal Title
  
  Cancer Biol Ther
  
  Volume: 13 Pages: 369-378
- URL
  http://dx.doi.org/10.4161/cbt.19238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590994
[Journal Article] Rapamycin induces p53-independent apoptosis through the mitochondrial pathway in non-small cell lung cancer cells2012
- Author(s)
  Miyake N, Chikumi H, Takata M, Nakamoto M, Igishi T, Shimizu E
- Journal Title
  
  Oncology reports 28
  
  Volume: 28 Pages: 848-854
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22313637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590863
[Journal Article] Diagnostic and Prognostic Impact of Serum Soluble UL16-Binding Protein 2 in Lung Cancer Patients2012
- Author(s)
  Yamaguchi K, Chikumi H, et al
- Journal Title
  
  Cancer Science
  
  Volume: 103(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590994
[Journal Article] Lack of AKT activation in lung cancer cells with EGFR mutation is a novel marker of cetuximab sensitivity2012
- Author(s)
  Takata M, Chikumi H, et al
- Journal Title
  
  Cancer biology & therapy
  
  Volume: 13 Pages: 369-378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590994
[Journal Article] Therapeutic antitumor efficacy of anti-epidermal growth factor receptor antibody, cetuximab, against malignant pleural mesothelioma2012
- Author(s)
  Kurai J, Chikumi HT, Hamada H, Yano S, , Hashimoto K, Takata M, Sako T, Yamaguchi K, Kinoshita N, Watanabe M, Touge H, Makino H, Igishi Shimizu E
- Journal Title
  
  International Journal of Oncology
  
  Volume: 41 Issue: 5 Pages: 1610-1618
- DOI
  10.3892/ijo.2012.1607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590863, KAKENHI-PROJECT-24390209, KAKENHI-PLANNED-22112010
[Journal Article] Diagnostic and Prognostic Impact of Serum Soluble UL16-Binding Protein 2 in Lung Cancer Patients2012
- Author(s)
  Yamaguchi K, Chikumi H, Shimizu A, Takata M, Kinoshita N, Hashimoto K, Nakamoto M, Matsunaga S, Kurai J, Miyake N, Matsumoto S, Watanabe M, Yamasaki A, Igishi T, Burioka N, Shimizu E
- Journal Title
  
  Cancer Science
  
  Volume: (in press) Issue: 8 Pages: 1405-1413
- DOI
  10.1111/j.1349-7006.2012.02330.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590994, KAKENHI-PROJECT-22590863
[Journal Article] Lack of AKT activation in lung cancer cells with EGFR mutation is a novel marker of cetuximab sensitivity2012
- Author(s)
  Takata M, Chikumi H, Miyake N, Adachi K, Kanamori Y, Yamasaki A, Igishi T, Burioka N, Nanba E, Shimizu E
- Journal Title
  
  Cancer Biol Ther
  
  Volume: 13 Pages: 369-378
- URL
  http://dx.doi.org/10.4161/cbt.19238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590863
[Journal Article] Asthma : chronopharmacotherapy and the molecular clock.2010
- Author(s)
  Burioka N, Fukuoka Y, Koyanagi S, Miyata M, Takata M, Chikumi H, Watanabe M, Endo M, Sako T, Suyama H, Ohdo S, Shimizu E.
- Journal Title
  
  Adv Drug Deliv Rev 62
  
  Pages: 946-955
- Data Source
  KAKENHI-PROJECT-20590923
[Journal Article] Influence of intermittent hypoxia on the signal transduction pathways to inflammatory response and circadian clock regulation.2009
- Author(s)
  Burioka N, Koyanagi S, Fukuoka Y, Okazaki F, Fujioka T, Kusunose N, Endo M, Suyama H, Chikumi H, Ohdo S, Shimizu E.
- Journal Title
  
  Life Sci 85
  
  Pages: 372-378
- Data Source
  KAKENHI-PROJECT-20590923
[Journal Article] Clock gene dysfunction in patients with obstructive sleep apnea syndrome.2008
- Author(s)
  Burioka N, Koyanagi S, Takata M, Endo M, Fukuoka Y, Miyata M, Takeda K, Chikumi H, Ohdo S, Shimizu E.
- Journal Title
  
  Eur Respir J 32
  
  Pages: 105-112
- Data Source
  KAKENHI-PROJECT-20590923
[Journal Article] Treatment with β_2-adrenoceptor agonist in vivo induces human clock gene, Per1, mRNA expression in peripheral blood2007
- Author(s)
  Burioka N, Takata M, Endo M, Miyata M, Takeda K, Chikumi H, Tomita K, Fukuoka Y, Nakazaki H, Sano H, Shimizu E
- Journal Title
  
  Chronobiol Int 24(1)
  
  Pages: 183-189
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590791
[Journal Article] Function of clock genes in disease: Influence of medication for bronchial asthma on circadian gene.2007
- Author(s)
  Burioka N, Fukuoka Y, Takata M, Endo M, Miyata M, Chikumi H, Tomita K, Kodani M, Touge H, Takeda K, Sumikawa T, Yamaguchi K, Ueda Y, Nakazaki H, Suyama H, Yamasaki A, Sano H, Igishi T, Shimizu E
- Journal Title
  
  J Pharmacol Sci 103(2)
  
  Pages: 144-149
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590791
[Journal Article] Suppression of phosphatidylinositol 3-kinase/Akt signaling pathway is a determinant of the sensitivity to a novel histone deacetylase inhibitor, FK228, in lung adenocarcinoma cells.2005
- Author(s)
  Kodani M, Igishi T, Matsumoto S, Chikumi H Shigeoka Y, Nakanishi H, Morita M, Yasuda K Hitsuda Y, Shimizu E.
- Journal Title
  
  Oncol Rep. 13(3)
  
  Pages: 477-477
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590811
[Journal Article] Measurement of Pseudomonas aeruginosa multidrug efflux pumps by quantitative real-time polymerase chain reaction.2005
- Author(s)
  Yoneda K, Chikumi H. et al.
- Journal Title
  
  FEMS Microbiol Lett 243
  
  Pages: 125-125
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590811
[Journal Article] Suppression of phosphatydylinositol 3-kinase/Akt signaling pathway is a de-terminat of the sensitivity to a novel histone deacylase inhbitor,FK228,in lung adenocarcinima cells2005
- Author(s)
  Kodani M, Igishi T, Matsumoto S, Chikumi H. et al.
- Journal Title
  
  Oncology Reports 13
  
  Pages: 477-477
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590811
[Journal Article] Measurement of Pseudomonas aeruginosa multidrug efflux pumps by quantitative real-time polymerase chain reaction.2005
- Author(s)
  Yoneda K, Chikumi H, Murata T, Gotoh N, Yamamoto H, Fujiwara H, Nishino T, Shimizu E
- Journal Title
  
  FEMS Microbiol Lett. 243(1)
  
  Pages: 125-125
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590811
[Journal Article] Suppression of phosphatydylinositol 3-kinase/Akt signaling pathway is a de-terminat of the sensitivity to a novel histone deacylase inhbitor, FK228, in lung adenocarcinima cells2004
- Author(s)
  Kodani M, Igishi T, Matsumoto S, Chikumi H. et al.
- Journal Title
  
  Oncology Reports 13
  
  Pages: 477-477
- Data Source
  KAKENHI-PROJECT-15590811
[Journal Article] Down-regulation of inducible nitric oxide synthase by lysophosphatidic acid in human respiratory epithelial cells2004
- Author(s)
  Kadowaki S, Chikumi H. et al.
- Journal Title
  
  Mol Cell Biochem 262
  
  Pages: 51-51
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590811
[Journal Article] Cellular immune profile in patients with non-small cell lung cancer after weekly paclitaxel therapy.2004
- Author(s)
  Sako T, Burioka N, Yasuda K, Tomita K, Miyata M, Kurai J, Chikumi H, Watanabe M, Suyama H, Fukuoka Y, Ueda Y, Shimizu E.
- Journal Title
  
  Acta Oncol. 43(1)
  
  Pages: 15-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590811
[Journal Article] Homo-and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential.2004
- Author(s)
  Chikumi H, Barac A, Behbahani B, Gao Y, Teramoto H, Zheng Y, Gutkind JS.
- Journal Title
  
  Oncogene. 23(1)
  
  Pages: 233-233
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590811
[Journal Article] Down-regulation of inducible nitric oxide synthase by lysophosphatidic acid in human respiratory epithelial cells.2004
- Author(s)
  Kadowaki S, Chikumi H, Yamamoto H, Yoneda K, Yamasaki A, Sato K, Shimizu E.
- Journal Title
  
  Mol Cell Biochem. 262(1-2)
  
  Pages: 51-51
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590811
[Journal Article] Homo- and hetero-oligomerization of PDZ-RhoGEF,LARG and pll5RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential2004
- Author(s)
  Chikumi H, Barac A. et al.
- Journal Title
  
  Oncogene 23
  
  Pages: 233-233
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590811
[Journal Article] Clock gene dysfunction in patients with obstructive sleep apnea syndrome.
- Author(s)
  Burioka N, Koyanagi S, Endo M, Takata M, Fukuoka Y, Miyata M, Takeda K, Chikumi H, Ohdo S, Shimizu E
- Journal Title
  
  Eur Respir J (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590791
[Journal Article] Rapamycin induces p53-independent apoptosis through the mitochondrial pathway in non-small cell lung cancer cells Oncology reports
- Author(s)
  Miyake N, Chikumi H, Takata M, Nakamoto M, Igishi T, Shimizu E
- Volume
  (in press)
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22313637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590994
[Presentation] 地域サーベイランスシステム(IHOCS)による鳥取県における薬剤耐性菌分離状況の分析　3年間の稼働報告2020
- Author(s)
  森下奨太、千酌浩樹　他
- Organizer
  第35回　日本環境感染学会総会
- Data Source
  KAKENHI-PROJECT-18K09972
[Presentation] 抗菌薬適正使用を推進する新しい地域抗菌薬使用量サーベイランスシステム（IHOCS ver2.0）の構築－鳥取県での経験－2020
- Author(s)
  高根　浩、千酌浩樹
- Organizer
  第35回日本環境感染学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K09972
[Presentation] 地域サーベイランスシステム(IHOCS)による鳥取県における薬剤耐性菌分離状況の分析～3年間の稼働報告～2020
- Author(s)
  森下奨太、千酌浩樹
- Organizer
  第35回日本環境感染学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K09972
[Presentation] アウトブレイク事例から学ぶ～対策の見直し　薬剤耐性菌2020
- Author(s)
  千酌浩樹
- Organizer
  第35回　日本環境感染学会総会
- Data Source
  KAKENHI-PROJECT-18K09972
[Presentation] 抗菌薬適正使用を推進する新しい地域抗菌薬使用量サーベイランスシステム(IHOCS ver2.0)の構築　鳥取県での経験2020
- Author(s)
  高根浩、千酌浩樹　他
- Organizer
  第35回　日本環境感染学会総会
- Data Source
  KAKENHI-PROJECT-18K09972
[Presentation] 血液培養検査を再考する2017
- Author(s)
  千酌浩樹
- Organizer
  第32回日本環境感染学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-26462755
[Presentation] 薬剤耐性対策を考慮した感染症診療の実際2017
- Author(s)
  千酌浩樹
- Organizer
  平成29年度日本内科学会生涯教育講演会
- Invited
- Data Source
  KAKENHI-PROJECT-26462755
[Presentation] 感染症と教育卒前卒後にわたる感染症・感染制御教育への取り組み2016
- Author(s)
  千酌浩樹
- Organizer
  第90回日本感染症学会総会・学術講演会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-04-15
- Data Source
  KAKENHI-PROJECT-26462755
[Presentation] 高齢者感染症のpitfall (教育講演）2016
- Author(s)
  千酌浩樹
- Organizer
  第64回日本学療法学会西日本支部総会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県宜野湾市）
- Year and Date
  2016-11-25
- Invited
- Data Source
  KAKENHI-PROJECT-26462755
[Presentation] 肺癌細胞におけるEGFR阻害剤耐性獲得時の浸潤能とその機序の検討2014
- Author(s)
  高田美也子、泉大樹、千酌浩樹、三宅直美、牧野晴彦、井岸正、清水英治
- Organizer
  第23回日本がん転移学会総会
- Place of Presentation
  金沢市文化ホール（金沢）
- Year and Date
  2014-07-11
- Data Source
  KAKENHI-PROJECT-26462755
[Presentation] 肺癌細胞におけるEGFR阻害剤耐性獲得時の浸潤能とその機序の検討2014
- Author(s)
  高田美也子、泉大樹、千酌浩樹、三宅直美、牧野晴彦、井岸正、清水英治
- Organizer
  第23回日本がん転移学会総会
- Place of Presentation
  金沢市文化ホール（金沢市）
- Year and Date
  2014-07-11
- Data Source
  KAKENHI-PROJECT-26461159
[Presentation] Circulating serum ULBP2 in patients with various lung diseases2012
- Author(s)
  Kinoshita N, Chikumi H, Yamaguchi K, Takata M, Nakamoto M, Kodani M, Matsumoto S, Kawasaki Y, Tadashi I, Shimizu E
- Organizer
  第52回日本呼吸器学会学術講演会
- Place of Presentation
  神戸コンベンションセンター(神戸)
- Year and Date
  2012-04-22
- Data Source
  KAKENHI-PROJECT-22590863
[Presentation] Circulating serum ULBP2 in patients with various lung diseases2012
- Author(s)
  Kinoshita N, Chikumi H, et al
- Organizer
  第52回日本呼吸器学会学術講演会
- Place of Presentation
  神戸コンベンションセンター(神戸)
- Year and Date
  2012-04-22
- Data Source
  KAKENHI-PROJECT-21590994
[Presentation] Development of a novel combination therapy using cetuximab2012
- Author(s)
  Takata M, Chikumi H, Igishi T, Burioka N, Yamasaki A, Nakamoto M, Kinoshita N, Kitaura T, Okada K, Shimizu E
- Organizer
  第52回日本呼吸器学会学術講演会
- Place of Presentation
  神戸コンベンションセンター(神戸)
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PROJECT-22590863
[Presentation] Soluble UL16 binding protein 2 is elevated in the sera of lung cancer patients2010
- Author(s)
  K.Yamaguchi, H.Chikumi
- Organizer
  AACR 101^<st> Annual meeting 2010
- Place of Presentation
  米国、ワシントンDC
- Year and Date
  2010-04-20
- Data Source
  KAKENHI-PROJECT-21590994
[Presentation] Antibody-dependent cellular cytotoxicity mediated by cetuximab against mesothelioma cells2010
- Author(s)
  Chikumi H, Kurai J, Kinoshita N, Nakamoto M, Matsumoto S, Igishi T, Hamada H, Yano S, Shimizu E
- Organizer
  The 10th international conference of the international mesothelioma interest group
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22590863
[Presentation] Antibody-dependent cellular cytotoxicity mediated by cetuximab against mesothelioma cells2010
- Author(s)
  Chikumi H, Kurai J, Kinoshita N, Nakamoto M, Matsumoto S, Igishi T, Hamada H, Yano S, Shimizu E
- Organizer
  The 10th international conference of the international mesothelioma interest group(Workshop : Immunotherapy : bench to bedside-II)
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21590994
[Presentation] Soluble UL16 binding protein 2 is elevated in the sera of lung cancer patients2010
- Author(s)
  Yamaguchi K, Chikumi H, Kinoshita N, Shimizu A, Hashimoto K, Kurai J, Yamasaki A, Nakamoto M, Matsumoto S, Takata M, Igishi T, Burioka N, Shimizu E
- Organizer
  American Association for Cancer Research 101st Annual Meeting 2010
- Place of Presentation
  Washington DC, USA
- Year and Date
  2010-04-20
- Data Source
  KAKENHI-PROJECT-21590994
[Presentation] Antibody-Dependent Cellular Cytotoxicity Mediated by Cetuximab against Mesothehoma Cells.2010
- Author(s)
  H.Chikumi, E.Shimizu.
- Organizer
  The 101th International Conference of the International Mesothelioma Interest Group.
- Place of Presentation
  京都国際会議場(京都)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22590863
[Presentation] Biomarkers of immunological therapy of lung cancer2009
- Author(s)
  Chikumi, H., Shimizu, E
- Organizer
  第49回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2009-06-13
- Data Source
  KAKENHI-PROJECT-21590994

1. SHIMIZU Eiji (50187449)

# of Collaborated Projects: 7 results

# of Collaborated Products: 27 results
2. 高田美也子 (50523643)

# of Collaborated Projects: 5 results

# of Collaborated Products: 8 results
3. BURIOKA Naoto (50252854)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
4. MIYAKE Naomi (90747205)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
5. YAMAGUCHI Kousuke (60529402)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 中本成紀 (70379642)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KINOSHITA Naoki (40750336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TERAMO Hidemi (80304236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YASUDA Kazuhito (90322213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. IGISHI Tadashi (80273895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KISHIMOTO Takuji (00116394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 景山誠二 (60252706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

CHIKUMI Hiroki 千酌 浩樹

Research Projects

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Co-Researchers

COVID-19に対する可溶性ULBP2制御によるNK細胞療法の開発Principal Investigator

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Development of a novel surveillance system integrating local and global AMR informationPrincipal Investigator

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A novel therapy for sepsis by regulating soluble ULBP2Principal Investigator

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Development of novel biomarker for cetuximab therapy in lung cancerPrincipal Investigator

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Analysis of activation mechanisms of Rho and RhoGEFs as a new molecular target for lung cancer therapy.Principal Investigator

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[Journal Article] Clinical characteristics and treatment outcomes of carbapenem-resistant Enterobacterales infections in Japan2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of infections in orthopedic patients using next-generation sequencing2021

CHIKUMI Hiroki 千酌浩樹

[Journal Article] 【Antimicrobial Stewardship Program(ASP)の理論と実際】 ASP推進における医師の役割　患者にとって有効で,かつ耐性菌を過剰に生じさせないためには2016