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HAYASHI TOMOHITO  林 智人

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HAYASHI Tomohito  林 智人

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Researcher Number 90297630
Other IDs
Affiliation (based on the past Project Information) *help 2020 – 2022: 国立研究開発法人農業・食品産業技術総合研究機構, 動物衛生研究部門, グループ長
2017: 国立研究開発法人農業・食品産業技術総合研究機構, 動物衛生研究部門, 上席研究員
2016 – 2017: 国立研究開発法人農業・食品産業技術総合研究機構, 動物衛生研究部門, ユニット長
2015: 国立研究開発法人農業・食品産業技術総合研究機構, その他部局等, 研究員
2008: National Agricultural Research Organization, 動物衛生研究所, 主任研究員 … More
2008: National Agricultural Research Organization, 動物衛生研究所生産病研究チーム, 主任研究員
2006 – 2007: 東京理科大学, 生命科学研究所, 講師
1999 – 2002: 東京理科大学, 生命科学研究所, 助手 Less
Review Section/Research Field
Principal Investigator
Clinical veterinary science
Except Principal Investigator
Veterinary medical science / Basic Section 42020:Veterinary medical science-related / Basic veterinary science/Basic zootechnical science / Applied animal science
Keywords
Principal Investigator
ウシ乳房炎 / 免疫応答 / 乳腺上皮細胞 / スーパー抗原性毒素 / 黄色ブドウ球菌
Except Principal Investigator
乳房炎 / 感染症 / 黄色ブドウ球菌 / 免疫学 / 獣医学 … More / 家畜サルモネラ症 / 弱毒化 / 細菌生ワクチン / ウシ乳房炎 / サルモネラ症 / 食中毒 / 大腸菌 / サルモネラ属菌 / 非天然アミノ酸 / 生物学的封じ込め / 生ワクチン / 動物 / 生体分子 / 好中球 / 畜産学 / 形質転換 / 病原微生物 / トランスポゾン / signal transduction / IgE receptor / basophils / mast cells / Allergy / シグナル伝達 / アレルギー / 医療・福祉 / blood protein polymorphism / microsatellite marker / mastitis / superantigen / MHC class II / breeding of experimental animal line / closed population / goat / 免疫応答 / 寒地適応 / 血液蛋白多型 / マイクロサテライトマーカー / スーパー抗原 / MHCクラスII / 系統造成 / 閉鎖繁殖 / ヤギ Less
  • Research Projects

    (6 results)
  • Research Products

    (31 results)
  • Co-Researchers

    (15 People)
  •  Development of highly-efficient and safe live bacterial vaccines using viability-controlable pathogens

    • Principal Investigator
      Kato Yusuke
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      National Agriculture and Food Research Organization
  •  Construction of a transposon insertion mutants library in Staphylococcus aureus isolated from bovine mastitis for development of a novel strategy to treat mastitis

    • Principal Investigator
      Yoneyama Hiroshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Veterinary medical science
    • Research Institution
      Tohoku University
  •  Role of prolonged release of CXCL8 during bovine mastitis caused by intramammary infection of Staphylococcus aureus

    • Principal Investigator
      Watanabe Atsushi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Veterinary medical science
    • Research Institution
      National Agriculture and Food Research Organization
  •  Effect of staphylococcal superantigen on the immuneresponsibility of the bovine mammary epithelial cells.Principal Investigator

    • Principal Investigator
      HAYASHI Tomohito
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Clinical veterinary science
    • Research Institution
      National Agricultural Research Organization
      Tokyo University of Science
  •  Pathophysiological roles of basophils and mast cells in allergic inflammations

    • Principal Investigator
      GOITSUKA Ryo
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      Tokyo University of Science
  •  Production of goat lines selected by genes of MHC class II and challenge for improve to disease resistance

    • Principal Investigator
      AMANO Takashi
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied animal science
    • Research Institution
      Tokyo University of Agriculture

All 2022 2016 2009 2008 2007 2006

All Journal Article Presentation Book

  • [Book] Mastitis Control : Rapid and Effective Method for Separation for Staphylococcus aureus from Somatic Cells in Mastitis Milk2008

    • Author(s)
      Tomohito Hayashi
    • Total Pages
      4
    • Publisher
      Wageningen Academic Publishers
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Book] 「免疫」システムを担う組織・細胞・分子とその機能的役割2008

    • Author(s)
      林智人
    • Total Pages
      10
    • Publisher
      家畜診療
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Book] 技術の窓、PCR法による乳汁中黄色ブドウ球菌特異遺伝子の迅速検出法2008

    • Author(s)
      林智人
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Book] 家畜診療、「免疫」システムを担う組織・細胞・分子とその機能的役割2008

    • Author(s)
      林智人
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Book] Mastitis Control : Effect of Intramammary Injection of RbGM-CSF on Neutrophils Function of Blood and Milk in Holstein Cows with Subclinical Mastitis2008

    • Author(s)
      Tomomi Ozawa、Yoshio Kiku、Shigeki Inumaru、Sanki Hasegawa、Shiro KushibikiTomohito Hayashi、Hideyuki Takahashi
    • Publisher
      Wageningen Academic Publishers
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Book] PCR法による乳汁中黄色ブドウ球菌特異遺伝子の迅速検出法2008

    • Author(s)
      林智人
    • Total Pages
      1
    • Publisher
      技術の窓
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Book] Mastitis Control : Effect of Intramammary Injection of Liposomal RbGM-CSF on Milk and Peripheral Blood Mononuclear Cells of Subpopulation in Holstein Cows with Naturally Infected-subclinical Mastitis2008

    • Author(s)
      Yoshio Kiku、Tomomi Ozawa、Shigeki Inumaru、Shiro Kushibiki、Tomohito Hayashi、Hideyuki Takahashi
    • Publisher
      Wageningen Academic Publishers
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Book] Mastitis Control : Effect of Intramammary Injection of Liposomal RbGM-CSF on Milk and Peripheral Blood Mononuclear Cells of Subpopulation in Holstein Cows with Naturally Infected-subclinical Mastitis2008

    • Author(s)
      Tomohito Hayashi、Munehiro Kubota、Keiko Iwasaki、Kengo Sakaguchi、Ryo Abe、Hiromichi Ohtsuka、Yoshio Kiku、Tomomi Ozawa、Hideyuki Takahashi
    • Publisher
      Wageningen Academic Publishers
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Journal Article] The cell wall component lipoteichoic acid of <i>Staphylococcus aureus</i> induces chemokine gene expression in bovine mammary epithelial cells2016

    • Author(s)
      Yoshio Kiku, Yuya Nagasawa, Fuyuko Tanabe, Kazue Sugawara, Atsushi Watanabe, Eiji Hata, Tomomi Ozawa. Kei-ichi Nakajima, Toshiro Arai, Tomohito Hayashi
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 78 Issue: 9 Pages: 1505-1510

    • DOI

      10.1292/jvms.15-0706

    • NAID

      130005598048

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07731
  • [Journal Article] ウシ組換えGM-CSF乳房内投与が潜在性乳房炎牛の乳汁および末梢血好中球に及ぼす影響2009

    • Author(s)
      尾澤知美、菊佳男、犬丸茂樹、長谷川三喜、櫛引史郎、林智人、高橋秀之
    • Journal Title

      日本乳房炎研究会報 13

      Pages: 61-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Journal Article] 乳房炎乳汁から迅速かつ効率よく黄色ブドウ球菌を分離する方法の開発2009

    • Author(s)
      林智人、窪田宗広、岩崎圭子、坂口憲吾、安部良、大塚浩通、菊佳男、尾澤知美、高橋秀之
    • Journal Title

      本乳房炎研究会報 13

      Pages: 39-47

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Journal Article] 乳房炎乳汁から迅速かつ効率よく黄色ブドウ球菌を分離する方法の開発2009

    • Author(s)
      林智人
    • Journal Title

      日本乳房炎研究会報 13

      Pages: 39-47

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Journal Article] 実験的大腸菌性乳房炎における臨床症状と血中サイトカインの関係, 乳房炎乳汁から迅速かつ効率よく黄色ブドウ球菌を分離する方法の開発2009

    • Author(s)
      菊佳男、岡田洋之、堤隆一、尾澤知美、林智人、高橋秀之
    • Journal Title

      日本乳房炎研究会報 13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Journal Article] Distinct regulatory functions of SLP-76 and MIST in NK cell cytotoxicity and IFN-g production2008

    • Author(s)
      Hidano, S., Sasanuma, H., Ohshima, K., Seino, K-I., Kumar, L., Hayashi, K., Hikida, M., Kurosaki, T., Taniguchi, M., Geha, R. S., Kitamura, D., Goitsuka, R
    • Journal Title

      Int. Immunol (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18380176
  • [Journal Article] Rapid and effective method for separation of Staphylococcus aureus from somatic cell in mastitis milk.2008

    • Author(s)
      窪田宗弘、林智人、岩崎圭子、大塚浩通、小比類巻正幸、川村清市、坂口謙吾、安部良
    • Journal Title

      Journal of Dairy Science 第90巻

      Pages: 4100-4107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Journal Article] Infection and Immunity2007

    • Author(s)
      Zhao J、林智人、Saarinen S、加藤秀人、今西健一、切代照雄、安部 良、内山竹彦、三好(秋山)徹
    • Journal Title

      Cloning, expression and characterization of the superantigen streptococcal pyrogenic exotoxin-G from Streptococcus dysgalactiae 第75巻

      Pages: 1721-1729

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Journal Article] Dual function for the adaptor MIST in IFN-g production by NK and CD4+NKT cells regulated by the Src-kinase Fgr2006

    • Author(s)
      Sasanuma, H., Tatsuno, A., Hidano, S., Ohshima, K., Matsuzaki, Y., Hayashi, K., Lowell, C. A., Kitamura, D. Goitsuka, R
    • Journal Title

      Blood 107(9)

      Pages: 3647-3655

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18380176
  • [Journal Article] BASH-novel PKC-Raf-1 pathway of pre-BCR signaling induces k gene rearrangement2006

    • Author(s)
      Yamamoto, M., Hayashi, K., Nojima, T., Matsuzaki, Y., Kawano, Y., Karasuyama, H., Goitsuka, R., Kitamura, D
    • Journal Title

      Blood 108(8)

      Pages: 2703-2711

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18380176
  • [Journal Article] Double knockout mice show BASH and PKCd have different epistatic relationships in B cell maturation and CD40-mediated activation2006

    • Author(s)
      Nojima, T., Hayashi, K., Goitsuka, R., Nakayama, K., Nakayama, K.-i. Kitamura, D
    • Journal Title

      Immunol. Lett 105(1)

      Pages: 48-54

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18380176
  • [Presentation] 生死をコントロールできる病原細菌を用いた高効率・高安全性ワクチンの構築2022

    • Author(s)
      加藤祐輔、長澤裕哉、中山ももこ、小川洋介、アリバムスワミシャ・デビ、杉山碧、江口正浩、林智人
    • Organizer
      日本農芸化学会2022年度大会
    • Data Source
      KAKENHI-PROJECT-20H03158
  • [Presentation] 黄色ブドウ球菌(SA)の死菌接種によって産生されるポリクローナル抗体はSAに対する増殖阻害効果を有する2016

    • Author(s)
      古川睦実、米山裕、秦英司、岩野英知、樋口豪紀、安藤太助、佐藤美佳、林智人、菊佳男、長澤裕哉、新實香奈枝、宇佐美克紀、佐々木志保、伊藤駿、渡邊康一、麻生久、野地智法
    • Organizer
      第6回家畜感染症学会学術集会
    • Place of Presentation
      九州大学西新プラザ(福岡県福岡市)
    • Year and Date
      2016-12-02
    • Data Source
      KAKENHI-PROJECT-15K14852
  • [Presentation] リポソーム包埋rbGM-CSF乳房炎罹患乳房内投与による乳汁および末梢血単核球表面抗原への影響と乳房炎治療効果の検討2009

    • Author(s)
      菊佳男、尾澤知美、櫛引史郎、犬丸茂樹、林智人、長谷川三喜、保田立二、高橋秀之
    • Organizer
      平成20年度日本獣医師会学会年次大会
    • Place of Presentation
      盛岡
    • Year and Date
      2009-01-23
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Presentation] Effect of Intramammary Injection of Liposomal RbGM-CSF on Milk and Peripheral Blood Mononuclear Cells of Subpopulation in Holstein Cows with Naturally Infected-subclinical Mastitis2008

    • Author(s)
      Yoshio Kiku、Tomomi Ozawa、Shigeki Inumaru、Shiro Kushibiki、Tomohito Hayashi、Hideyuki Takahashi
    • Organizer
      International Conference of Mastitis control
    • Place of Presentation
      オランダ
    • Year and Date
      2008-09-30
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Presentation] Rapid and Effective Method for Separation for Staphylococcus aureus from Somatic Cells in Mastitis Milk2008

    • Author(s)
      Tomohito Hayashi
    • Organizer
      International Conference of Mastitis control
    • Place of Presentation
      オランダ、ハーグ
    • Year and Date
      2008-09-30
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Presentation] 実験的大腸菌性乳房炎における臨床症状と血中サイトカインの関係2008

    • Author(s)
      菊佳男、岡田洋之、堤隆一、尾澤知美、林智人、高橋秀之
    • Organizer
      第13回日本乳房炎研究会学術大会
    • Place of Presentation
      つくば
    • Year and Date
      2008-11-07
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Presentation] Effect of Intramammary Injection of RbGM-CSF on Neutrophils Function of Blood and Milk in Holstein Cows with Subclinical Mastitis2008

    • Author(s)
      Tomomi Ozawa、Yoshio Kiku、Shigeki Inumaru、Sanki Hasegawa、Shiro Kushibiki、Tomohito Hayashi、Hideyuki Takahashi
    • Organizer
      International Conference of Mastitis control
    • Place of Presentation
      オランダ
    • Year and Date
      2008-09-30
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Presentation] ウシ組換えGM-CSF乳房内投与が潜在性乳房炎牛の乳汁および末梢血好中球に及ぼす影響2008

    • Author(s)
      尾澤知美、菊佳男、犬丸茂樹、長谷川三喜、櫛引史郎、林智人、高橋秀之
    • Organizer
      第13回日本乳房炎研究会学術大会
    • Place of Presentation
      つくば
    • Year and Date
      2008-11-07
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Presentation] 全身性免疫と粘膜性免疫2008

    • Author(s)
      林智人
    • Organizer
      第3回日本家畜臨床感染症研究会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-05
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Presentation] 乳房炎乳汁から迅速かつ効率よく黄色ブドウ球菌を分離する方法の開発2008

    • Author(s)
      林智人、窪田宗広、岩崎圭子、坂口憲吾、安部良、大塚浩通、菊佳男、尾澤知美、高橋秀之
    • Organizer
      第13回日本乳房炎研究会学術大会
    • Place of Presentation
      つくば
    • Year and Date
      2008-11-07
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Presentation] Rapid and Effective Method for Separation for Staphylococcus aureus from Somatic Cells in Mastitis Milk2008

    • Author(s)
      Tomohito Hayashi、Munehiro Kubota、Keiko Iwasaki、Kengo Sakaguchi、Ryo Abe、Hiromichi Ohtsuka、Yoshio Kiku、Tomomi Ozawa、Hideyuki Takahashi
    • Organizer
      International Conference of Mastitis control
    • Place of Presentation
      オランダ
    • Year and Date
      2008-09-30
    • Data Source
      KAKENHI-PROJECT-19580374
  • [Presentation] 反芻家畜における乳房炎発症の免疫学的考察 =特に、乳腺上皮細胞におよぼす細菌性スーパー抗原の影響について=2007

    • Author(s)
      林智人
    • Organizer
      日本獣医生命科学大学学術交流会
    • Place of Presentation
      宮城県・仙台国際センター
    • Year and Date
      2007-10-07
    • Data Source
      KAKENHI-PROJECT-19580374
  • 1.  HATA EIJI (50355153)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  AMANO Takashi (90078147)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  ABE Ryo (20159453)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  NOMURA Koh (60277241)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  YOKOHAMA Michinari (40220561)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  GOITSUKA Ryo (50301552)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 7.  Yoneyama Hiroshi (10220774)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  Watanabe Atsushi (60442810)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KIMURA KAZUHIRO (30192561)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KIMURA TAKASHI (90261338)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  NAKAJIMA KEI-ICHI (70362150)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  Kato Yusuke (60214409)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  野地 智法 (10708001)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 14.  江口 正浩 (00312215)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  長澤 裕哉 (20759352)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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