KAMOSHITA Nobuhiko 鴨下信彦

Researcher Number	90302603
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2023: 自治医科大学, 医学部, 講師 2010 – 2012: 自治医科大学, 医学部, 講師 1999 – 2001: 東京大学, 医科学研究所, 助手
Review Section/Research Field	Principal Investigator Basic Section 49010:Pathological biochemistry-related / Virology / Virology Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Virology
Keywords	Principal Investigator RNA / C型肝炎ウイルス / 酵素局在 / 翻訳開始 / サプレッサーtRNA / CpGメチル化 / 開始tRNA / (アンチコドン改変tRNA) / ナンセンスサプレッサーtRNA / RNAウイルス … More / ナンセンス変異遺伝病 / 変異tRNA / 終止コドンリードスルー / 内部認識翻訳開始機構(IRES) / 翻訳終止 / 選択的ポリA付加 / 発現制御 / 内部認識翻訳開始配列(IRES) / 翻訳 / termination readthrough / 選択的スプライシング / 転写後遺伝子発現 / 内部認識翻訳開始部位(internal ribosomal entry site) / 翻訳(translation) / RNA複製 / Cre-loxPシステム / 3′非翻訳領域 / IRES(internal ribosomal entry site) / RT-PCR / ミニ遺伝子 / RNAレプリコン / ウイルス複製の宿主因子 … More Except Principal Investigator 第VIII因子 / 血友病 / 肝臓類洞内皮細胞 / 遺伝子治療 / 再生医療 / 血友病A / 血液凝固第VIII因子 / Basolateral Sorting / Cytoplasmic Dynein / Cytopathic Effect / Poliovirus Receptor / Poliovirus / clathrin adaptor complex / 逆行性モーター蛋白質 / 軸索輸送 / ポリオウイルスレセプター / バソラテラルソーティング / 細胞質ダイニン / 細胞変性効果 / ポリオウイルス受容体 / ポリオウイルス Less

終止コドンリードスルーによる酵素局在の変化とナンセンス変異遺伝病の治療Principal Investigator
- Principal Investigator
  
  鴨下信彦
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Jichi Medical University
Elucidation of the origin of blood coagulation factor VIII-producing cells for the development of new hemophilia treatment
- Principal Investigator
  
  Ohmori Tsukasa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Jichi Medical University
Novel internal initiation mechanism of translation of h e p a t i t i s C virus RNAPrincipal Investigator
- Principal Investigator
  
  KAMOSHITA Nobuhiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Jichi Medical University
Neuropathogenesis caused by poliovirus and neural cell function
- Principal Investigator
  
  OHKA Seii
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
C型肝炎ウイルスRNAの細胞内複製:遺伝子型2b由来ミニ遺伝子の作製と解析Principal Investigator
- Principal Investigator
  
  鴨下信彦
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2012 2011 2010

All Journal Article Presentation

[Journal Article] Human nonsense mutations in primary hyperammonemia - Analysis of publicized patient mutations and variations in general populations in eight disease-causing genes2023
- Author(s)
  Nobuhiko Kamoshita, Takafumi Hiramoto, Yuji Kashiwakura, Morisada Hayakawa, Tsukasa Ohmori
- Journal Title
  
  Research Square
  
  Volume: 11 Pages: 1-23
- DOI
  10.21203/rs.3.rs-3090477/v1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07403
[Journal Article] Establishment of a megakaryoblastic cell line for conventional assessment of platelet calcium signaling2020
- Author(s)
  Saito H, Hayakawa M, Kamoshita N, Yasumoto A, Suzuki-Inoue K, Yatomi Y, Ohmori T
- Journal Title
  
  Int J Hematol
  
  Volume: in press Issue: 6 Pages: 786-794
- DOI
  10.1007/s12185-020-02853-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08370
[Journal Article] 変異tRNAによるRNAウイルスの翻訳解析2020
- Author(s)
  鴨下信彦
- Journal Title
  
  Medical Science Digest
  
  Volume: 46
- Data Source
  KAKENHI-PROJECT-19K07403
[Journal Article] Induction of IκBζ augments cytokine and chemokine production by IL-33 in mast cells.2020
- Author(s)
  Ohto-Ozaki H, Hayakawa M, Kamoshita N, Maruyama T, Tominaga S-I, Ohmori T
- Journal Title
  
  J Immunol.
  
  Volume: 204 Issue: 8 Pages: 2033-2042
- DOI
  10.4049/jimmunol.1900315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08370
[Presentation] Analysis of human nonsense mutations in primary hyperammonemia -Nucleotide changes in eight disease-causing genes in the literature and genomic databases2023
- Author(s)
  Kamoshita N., Kashiwakura Y., Hiramoto H., Hayakawa M., and Ohmori T.
- Organizer
  RNA2023 (Shingapore)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07403
[Presentation] Analysis of human nonsense mutations in primary hyperammonemia - Nucleotide changes in eight disease-causing genes in the literature and genomic databases.2023
- Author(s)
  Nobuhiko Kamoshita, Takafumi Hiramoto, Yuji Kashiwakura, Morisada Hayakawa, Tsukasa Ohmori
- Organizer
  RNA2023 (Singapore)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07403
[Presentation] Human nonsense nucleotide changes in primary hyperammonemia - Literature and database review of eight disease-causing genes2022
- Author(s)
  Kamoshita N., Kashiwakura Y., Hiramoto H., Hayakawa M., and Ohmori T.
- Organizer
  生命科学系学会合同年次大会・第45回日本分子生物学会年会・日本生物物理学会共催 (千葉)
- Data Source
  KAKENHI-PROJECT-19K07403
[Presentation] 文献およびゲノム解析データベースを利用したヒト疾患原因変異の解析例2022
- Author(s)
  KAMOSHITA Nobuhiko, HIRAMOTO Takafumi, KASHIWAKURA Yuji, HAYAKAWA Morisada, OHMORI Tsukasa
- Organizer
  トーゴーの日シンポジウム2022 (オンライン参加)
- Data Source
  KAKENHI-PROJECT-19K07403
[Presentation] Analysis of human Selenoprotein P (SELENOP) promoter activity.2021
- Author(s)
  Kamoshita N., Kashiwakura Y., Baatartsogt N., Hiramoto T., Hayakawa M., Ohmori T.
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07403
[Presentation] Translation without the initiator tRNA in hepatitis C virus RNA2021
- Author(s)
  Kamoshita N., Ohmori T
- Organizer
  第22回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-19K07403
[Presentation] ジシストロウイルスの終止コドンリードスルーにより翻訳されるアミノ酸配列2019
- Author(s)
  鴨下信彦, 富永眞一, 大森　司
- Organizer
  第21回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-19K07403
[Presentation] IL-33受容体ST2L/IL1RL1遺伝子座における選択的スプライシング2012
- Author(s)
  鴨下信彦, 為本浩至, 早川盛禎, 富永眞一
- Organizer
  第14回日本RNA学会年会
- Place of Presentation
  東北大学百周年記念会館川内萩ホール (宮城県)
- Data Source
  KAKENHI-PROJECT-22590413
[Presentation] IL-33受容体ST2L/IL1RL1遺伝子座における選択的スプライシング.2012
- Author(s)
  鴨下信彦, 為本浩至, 早川盛禎, 富永眞一
- Organizer
  第14回日本RNA学会年会
- Place of Presentation
  仙台
- Year and Date
  2012-07-19
- Data Source
  KAKENHI-PROJECT-22590413
[Presentation] Effects of ASF/SF2 and HuR/ELAV1 on alternative splicing in ST2 gene.2012
- Author(s)
  Kamoshita N, Tamemoto H, Hayakawa M, Tominaga S
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-22590413
[Presentation] ST2 and its related mRNA 図2.1 PSIV IGR IRESのA. 塩基配列、B.構造と、C. 構造の変化. A 中の矢印は表2.1で使用した欠失変異体の塩基残存部を示す.表2.1 PSIV IGR欠失変異体のreadthrough効率IGR 長第2シストロン相対活性141 nt 1.0066 nt 5.8345 nt 10.11expression in human cell lines2012
- Author(s)
  Kamoshita N, Tamemoto H, Hayakawa M, Tominaga S
- Organizer
  International Symposium in honor of Professor Uttam RajBhandary: From Innovations in Nu-cleic acids research to Regulation of Biological Processes
- Place of Presentation
  インド, バンガロール
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-22590413
[Presentation] ST2遺伝子の選択的スプライシングにおけるトランス因子の解析2012
- Author(s)
  Kamoshita, Tamamoto, Hayakawa, Tominaga
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  マリンメッセ福岡 (福岡県)
- Data Source
  KAKENHI-PROJECT-22590413
[Presentation] ST2 and its related mRNA expression in human cell lines2011
- Author(s)
  Kamoshita, Tamamoto, 他
- Organizer
  International Symposium in honor of Professor Uttam RajBhandary : From Innovations in Nucleic acids research to Regulation of Biological Processes
- Place of Presentation
  インド理科大学院(インド、バンガロール)
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22590413
[Presentation] Alternative splicing in ST2 gene2011
- Author(s)
  Kamoshita N, Tamemoto H, Hayakawa M, Tominaga S.
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22590413
[Presentation] Alternative splicing in ST2 gene2011
- Author(s)
  Kamoshita, Tamamoto, 他
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22590413
[Presentation] Ectodomain shedding of ST2L, a member of IL1 receptor family2010
- Author(s)
  Tamemoto, Ozaki, Kamoshita, 他
- Organizer
  BMB 2010
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22590413

1. OHKA Seii (80313097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. KUGE Shusuke (50186376)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Ohmori Tsukasa (70382843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 早川盛禎 (30326847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 長尾恭光 (80303874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAMOSHITA Nobuhiko 鴨下 信彦

Research Projects

Research Products

Co-Researchers

終止コドンリードスルーによる酵素局在の変化とナンセンス変異遺伝病の治療Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the origin of blood coagulation factor VIII-producing cells for the development of new hemophilia treatment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel internal initiation mechanism of translation of h e p a t i t i s C virus RNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Neuropathogenesis caused by poliovirus and neural cell function

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

C型肝炎ウイルスRNAの細胞内複製:遺伝子型2b由来ミニ遺伝子の作製と解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Human nonsense mutations in primary hyperammonemia - Analysis of publicized patient mutations and variations in general populations in eight disease-causing genes2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of a megakaryoblastic cell line for conventional assessment of platelet calcium signaling2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 変異tRNAによるRNAウイルスの翻訳解析2020

Author(s)

Journal Title

Data Source

[Journal Article] Induction of IκBζ augments cytokine and chemokine production by IL-33 in mast cells.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Analysis of human nonsense mutations in primary hyperammonemia -Nucleotide changes in eight disease-causing genes in the literature and genomic databases2023

Author(s)

Organizer

Data Source

[Presentation] Analysis of human nonsense mutations in primary hyperammonemia - Nucleotide changes in eight disease-causing genes in the literature and genomic databases.2023

Author(s)

Organizer

Data Source

[Presentation] Human nonsense nucleotide changes in primary hyperammonemia - Literature and database review of eight disease-causing genes2022

Author(s)

Organizer

Data Source

[Presentation] 文献およびゲノム解析データベースを利用したヒト疾患原因変異の解析例2022

Author(s)

Organizer

Data Source

[Presentation] Analysis of human Selenoprotein P (SELENOP) promoter activity.2021

Author(s)

Organizer

Data Source

[Presentation] Translation without the initiator tRNA in hepatitis C virus RNA2021

Author(s)

Organizer

Data Source

[Presentation] ジシストロウイルスの終止コドンリードスルーにより翻訳されるアミノ酸配列2019

Author(s)

Organizer

KAMOSHITA Nobuhiko 鴨下信彦