YOSHIDA Tsutomu 吉田功

… Alternative Names

吉田功ヨシダツトム

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Researcher Number	90316943
Other IDs
Affiliation (Current)	2025: 北里大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 北里大学, 医学部, 教授 2014 – 2020: 北里大学, 医学部, 准教授 2002 – 2013: 北里大学, 医学部, 講師 2001: 北里大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Human pathology / Basic Section 49020:Human pathology-related / Human pathology Except Principal Investigator Human pathology / Human pathology / Biological Sciences
Keywords	Principal Investigator 潰瘍性大腸炎 / 発癌 / 炎症性腸疾患 / クローン病 / olfactomedin-4 / OLFM4 / 炎症 / olfactomedin 4 / DNA修復 / p53R2 … More / p53 / エクソソーム / TEVs / 上皮間葉連関 / 悪性度 / Olfactomedin-4 / 悪性腫瘍 / EMT / b-catenin / olfactomedin4 / olfactmedin 4 / アポトーシス / 発現 / 潰瘍性大腸 / CITED2 / UC / 分子病理 / DNAマイクロアレイ / cDNAマイクロアレイ / 炎症性発癌 / G1チェックポイント / 異形成 / Gチェックポイント … More Except Principal Investigator 潰瘍性大腸炎 / 発がん / 間質細胞 / 慢性炎症 / chronic inflammation / genetic instability / carcinogenesis / ulcerative colitis / 大腸がん / マイクロダイセクション / 遺伝子不安定性 / 発癌 / remodeling / colorectal adenoma / colorectal cancer / stromal cells / リモデリング / 大腸腺腫 / 大腸癌 / colon cancer / microsatellite instability / microdissection / stromal cell / Microdissection / 遺伝子変異 / 細胞間相互作用 / 慢性臓器炎 / プロテオミックス / ゲノミックス / retinoic acid / aoptosis / GRIM-19 / NF-kB / myofibroblast / petoxiredoxin-1 / olfactomedin-4 / 粘膜リモデリング / 上皮細胞 / Fusobacterium varium / 16SrDNA / 16SrRNA遺伝子 / 腸内細菌 / p53 / 大腸 / 遺伝子異常 / 酸化ストレス Less

がん微小環境・エクソソーム解析による炎症性腸疾患関連腫瘍の病理学的特性解明Principal Investigator
- Principal Investigator
  
  吉田功
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kitasato University
The role of inflammatory biomarker OLMF4 to the malignancy of inflammatory bowel disease related tumorsPrincipal Investigator
- Principal Investigator
  
  Yoshida Tsutomu
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kitasato University
Pathological mechanism of inflammatory bowel disease by inflammatory biomarker OLFM4 inductionPrincipal Investigator
- Principal Investigator
  
  Yoshida Tsutomu
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
Molecular mechanism of OLFM4 and the significance as an inflammatory biomarker and therapeutic target for ulcerative colitisPrincipal Investigator
- Principal Investigator
  
  YOSHIDA Tsutomu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
Role of CITED2, a novel ulcerative colitis specific gene, to colitis and carcinogenesis.Principal Investigator
- Principal Investigator
  
  YOSHIDA Tsutomu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
Insufficient crosstalk between epithelium and stroma in chronic inflammation-carcinoma sequence: Analysis of a disease model
- Principal Investigator
  
  OKAYASU Isao
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
Analysis of p53-independent inflammatory carcinogenesis in the view of stromal microenvironmental changePrincipal Investigator
- Principal Investigator
  
  YOSHIDA Tsutomu
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
網羅的16SrDNA多型性解析による潰瘍性大腸炎原因菌の同定:病変局所からの検索
- Principal Investigator
  
  岡安勲
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
Mucosal remodeling and genetic instability of stromal cells in ulcerative colitis-associated tumorigenesis
- Principal Investigator
  
  OKAYASU Isao
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  KITASATO UNIVERSITY
慢性炎症におけるp53依存性DNA修復機構破綻による大腸癌発生機構の解明Principal Investigator
- Principal Investigator
  
  吉田功
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
Genetic instability of stromal cells in ulcerative colitis-associated carcinogenesis
- Principal Investigator
  
  OKAYASU Isao
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
潰瘍性大腸炎における粘膜微細環境の変化と遺伝子異常の蓄積:酸化ストレスによる発癌
- Principal Investigator
  
  OKAYASU Isao
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kitasato University
p53遺伝子・機能異常及びその関連分子解析による潰瘍性大腸炎発癌機構の解明Principal Investigator
- Principal Investigator
  
  吉田功
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University

[Book] Mucosal Remodeling and Alteration of Stromal Microenvironment in Ulcerative Colitis as Related to Colorectal Tumorigenesis2011
- Author(s)
  Isao Okayasu, Tsutomu Yoshida, Tetuo Mikami, Jun Mitsuhashi, Masaaki Ichinoe, Nobuyuki Yanagisawa, Wataru Tokuyama, Kiyomi Hana and Yuichi Ishibashi
- Publisher
  In-Tech
- Data Source
  KAKENHI-PROJECT-21590405
[Journal Article] Prenatal features of congenital peribronchial myofibroblastic tumor2024
- Author(s)
  Isohata Hitoshi、Yoshida Tsutomu、Sanoyama Itaru、Yamazaki Yu、Goto Hiroyuki、Yoshimura Yoshihiro、Hattori Kyoko、Shimaoka Takao、Sekiguchi Kazuki、Onishi Yoko、Tanaka Kiyoshi、Ochiai Daigo
- Journal Title
  
  Radiology Case Reports
  
  Volume: 19 Issue: 4 Pages: 1463-1467
- DOI
  10.1016/j.radcr.2024.01.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06911
[Journal Article] Utility of a rapid assay for prostaglandin E-major urinary metabolite as a biomarker in pediatric ulcerative colitis2023
- Author(s)
  Hagiwara Shin-ichiro、Abe Naoki、Hosoi Kenji、Hara Tomoko、Ishige Takashi、Shimizu Hirotaka、Mizuochi Tatsuki、Kakiuchi Toshihiko、Kunisaki Reiko、Matsuoka Ryo、Kondou Hiroki、Kakuta Fumihiko、Nakayama Yoshiko、Kimura Takeshi、Maeyama Takatoshi、Honma Hitoshi、Hirano Daishi、Saruta Masayuki、Yoshida Tsutomu、et al
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 9898-9907
- DOI
  10.1038/s41598-023-37145-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06911
[Journal Article] Clinicopathological features of PD-L1 protein expression, EBV positivity, and MSI status in patients with advanced gastric and esophagogastric junction adenocarcinoma in Japan2022
- Author(s)
  Yoshida Tsutomu、Ogura Go、Tanabe Mikiko、Hayashi Takuo、Ohbayashi Chiho、Azuma Mizutomo、Kunisaki Chikara、Akazawa Yoichi、Ozawa Soji、Matsumoto Sohei、Suzuki Takayoshi、Mitoro Akira、Fukunaga Tetsu、Shimizu Akiko、Fujimoto Go、Yao Takashi
- Journal Title
  
  Cancer Biology & Therapy
  
  Volume: 23 Issue: 1 Pages: 191-200
- DOI
  10.1080/15384047.2022.2038002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07026, KAKENHI-PROJECT-21K06911
[Journal Article] Cytology Reporting System for Lung Cancer from the Japan Lung Cancer Society and the Japanese Society of Clinical Cytology: An Extensive Study Containing More Benign Lesions2021
- Author(s)
  Yoshizawa Akihiko、Hiroshima Kenzo、Takenaka Akemi、Haba Reiji、Kawahara Kunimitsu、Minami Yuko、Kakinuma Hirokuni、Shibuki Yasuo、Miyake Shinji、Kajio Kenta、Kiyonaga Kana、Nagatomo Moe、Nishimura Sanako、Mano Masayuki、Matsubayashi Jun、Motoi Noriko、Nagao T.、Nakatsuka S.、Yoshida Tsutomu、Satoh Y.
- Journal Title
  
  Acta Cytologica
  
  Volume: 66 Issue: 2 Pages: 124-133
- DOI
  10.1159/000520426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07026, KAKENHI-PROJECT-21K06911
[Journal Article] Expression of CA2 and CA9 carbonic anhydrases in ulcerative colitis and ulcerative colitis‐associated colorectal cancer2020
- Author(s)
  Nakada Norihiro、Mikami Tetuo、Horie Kayo、Nagashio Ryo、Sakurai Yasutaka、Sanoyama Itaru、Yoshida Tsutomu、Sada Miwa、Kobayashi Kiyonori、Sato Yuichi、Okayasu Isao、Murakumo Yoshiki
- Journal Title
  
  Pathology International
  
  Volume: 70 Issue: 8 Pages: 523-532
- DOI
  10.1111/pin.12949
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07026, KAKENHI-PROJECT-19K07738, KAKENHI-PROJECT-19K16616, KAKENHI-PROJECT-18H02643
[Journal Article] Cytology Reporting System for Lung Cancer from the Japan Lung Cancer Society and Japanese Society of Clinical Cytology: An Interobserver Reproducibility Study and Risk of Malignancy Evaluation on Cytology Specimens2020
- Author(s)
  Hiroshima K、Yoshizawa A、Takenaka A、Haba R、Kawahara K、Minami Y、Kakinuma H、Shibuki Y、Miyake Si、Kajio K、Miyamoto K、Nagatomo M、Nishimura S、Mano Mi、Matsubayashi J、Motoi N、Nagao T、Nakatsuka S、Yoshida T、Satoh Y
- Journal Title
  
  Acta Cytologica
  
  Volume: - Issue: 5 Pages: 1-11
- DOI
  10.1159/000506431
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07026, KAKENHI-PROJECT-17K08705, KAKENHI-PROJECT-20K07417
[Journal Article] Analysis of BRCAness with multiplex ligation-dependent probe amplification using formalin-fixed and paraffin-embedded pancreatic ductal adenocarcinoma tissue obtained via endoscopic ultrasound-guided fine-needle aspiration biopsy2019
- Author(s)
  Okuwaki Kosuke、Masutani Hironori、Imaizumi Hiroshi、Yoshida Tsutomu、Kida Mitsuhiro、Iwai Tomohisa、Yamauchi Hiroshi、Tadehara Masayoshi、Adachi Kai、Watanabe Masafumi、Kurosu Takahiro、Koizumi Wasaburo
- Journal Title
  
  Pancreatology
  
  Volume: 19 Issue: 3 Pages: 419-423
- DOI
  10.1016/j.pan.2019.02.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07026
[Journal Article] Proposal for an Organ-Specific Chronic Inflammation - Remodeling - Carcinoma Sequence2019
- Author(s)
  Okayasu Isao、Ichinoe Masaaki、Yoshida Tsutomu
- Journal Title
  
  Gastrointestinal Disorders
  
  Volume: 1 Issue: 3 Pages: 341-357
- DOI
  10.3390/gidisord1030028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07026
[Journal Article] A retrospective study of definitive chemoradiotherapy in patients with resectable small cell neuroendocrine carcinoma of the esophagus.2019
- Author(s)
  Chikatoshi Katada, Shouko Komori, Tsutomu Yoshida, Shogo Kawakami, Akinori Watanabe, Kenji Ishido, Mizutomo Azuma, Takuya Wada, Kei Hosoda, Keishi Yamashita, Naoki Hiki, Satoshi Tanabe, Hiromichi Ishiyama, Wasaburo Koizumi.
- Journal Title
  
  Esophagus
  
  Volume: 47 Issue: 2 Pages: 716-719
- DOI
  10.1007/s10388-019-00686-9
- NAID
  40022193296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07026
[Journal Article] Peroxiredoxin 1 expression in active ulcerative colitis mucosa identified by proteome analysis and involvement of thioredoxin based on immunohistochemistry2019
- Author(s)
  Horie Kayo、Mikami Tetuo、Yoshida Tsutomu、Sato Yuichi、Okayasu Isao
- Journal Title
  
  Oncology Letters
  
  Volume: 15 Pages: 2364-2372
- DOI
  10.3892/ol.2017.7549
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07026, KAKENHI-PROJECT-15K08356
[Journal Article] Ciliated muconodular papillary tumors of the lung: Cytologic features and diagnostic pitfalls in intraoperative examinations2019
- Author(s)
  Mikubo Masashi、Maruyama Raito、Kakinuma Hirokuni、Yoshida Tsutomu、Satoh Yukitoshi
- Journal Title
  
  Diagnostic Cytopathology
  
  Volume: 47 Issue: 7 Pages: 716-719
- DOI
  10.1002/dc.24169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07026
[Journal Article] Vascular endothelial growth factor receptor 1 tyrosine kinase signaling facilitates healing of DSS-induced colitis by accumulation of Tregs in ulcer area2019
- Author(s)
  Betto Tomohiro、Amano Hideki、Ito Yoshiya、Eshima Koji、Yoshida Tsutomu、Matsui Yoshio、Yamane Sakiko、Inoue Tomoyoshi、Otaka Fumisato、Kobayashi Kiyonori、Koizumi Wasaburo、Shibuya Masabumi、Majima Masataka
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 111 Pages: 131-141
- DOI
  10.1016/j.biopha.2018.12.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07026, KAKENHI-PROJECT-18H02605, KAKENHI-PROJECT-15K08356, KAKENHI-PROJECT-19K09250
[Journal Article] EGFR mutation genotyping and ALK status determination in liquid-based cytology samples of non-small cell lung cancer2019
- Author(s)
  Yukitoshi Satoh, Yukiko Matsuo, Tatsuru Kuba, Kazuya Yamashita, Mariko Sawano, Shusaku Tozaka, Hirotsugu Yamazaki, Dai Sonoda, Masashi Mikubo, Nasahiro Naito, Yoshio Matsui, Kazu Shiomi, Tsutomu Yoshida, Yoshiki Murakumo
- Journal Title
  
  Virshows Archiv
  
  Volume: - Issue: 5 Pages: 753-762
- DOI
  10.1007/s00428-019-02692-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07026, KAKENHI-PROJECT-19K09291
[Journal Article] Reducing DNA damage by formaldehyde in liquid‐based cytology preservation solutions to enable the molecular testing of lung cancer specimens2018
- Author(s)
  Matsuo Yukiko、Yoshida Tsutomu、Yamashita Kazuya、Satoh Yukitoshi
- Journal Title
  
  Cancer Cytopathology
  
  Volume: 126 Issue: 12 Pages: 1011-1021
- DOI
  10.1002/cncy.22069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07026, KAKENHI-PROJECT-15K08356
[Journal Article] Molecular alterations in a new cell line (KU-Lu-MPPt3) established from a human lung adenocarcinoma with a micropapillary pattern2018
- Author(s)
  Matsuo Yukiko、Shiomi Kazu、Sonoda Dai、Mikubo Masashi、Naito Masahito、Matsui Yoshio、Yoshida Tsutomu、Satoh Yukitoshi
- Journal Title
  
  Journal of Cancer Research and Clinical Oncology
  
  Volume: 144 Issue: 1 Pages: 75-87
- DOI
  10.1007/s00432-017-2541-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10689, KAKENHI-PROJECT-18K07026, KAKENHI-PROJECT-15K08356
[Journal Article] Frequent β-catenin gene mutations in atypical polypoid adenomyoma of the uterus.2014
- Author(s)
  Takahashi, H., Yoshida, T., Matsumoto, T., Kameda, Y., Takano, Y., Tazo, Y., Inoue, H, Saegusa, M.
- Journal Title
  
  Hum Pathol
  
  Volume: 45 Issue: 1 Pages: 33-40
- DOI
  10.1016/j.humpath.2013.06.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590452, KAKENHI-PROJECT-24790361
[Journal Article] Unique and selective expression of L-amino acid transporter 1 in human tissue as well as being an aspect of oncofetal protein.2014
- Author(s)
  Nakada, N., Mikami, T., Hana, K., Ichinoe, M., Yanagisawa, N., Yoshida, T., Endou, H., Okayasu, I.
- Journal Title
  
  Histol Histopathol
  
  Volume: 29 Pages: 217-227
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590452
[Journal Article] Transcriptional upregulation of HIF-1α by NF-κB/p65 and its associations with β-catenin/p300 complexes in endometrial carcinoma cells.2013
- Author(s)
  Yoshida, T., Hashimura, M., Matsumoto, T., Tazo, Y., Inoue, H., Kuwata, T., Saegusa, M.
- Journal Title
  
  Lab Invest
  
  Volume: 93 Issue: 11 Pages: 1184-1193
- DOI
  10.1038/labinvest.2013.111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590452
[Journal Article] Transcriptional regulation of the alpha-1 type II collagen gene by NF-κB/p65 and Sox9 in the chondrocystic phenotype of uterine carcinosarcomas2013
- Author(s)
  Yoshida T, Hashimura M, Kuwata T, Matsmoto T, Suzuki E, Tazo Y, Nakajima H, Inukai M, Saegusa M
- Journal Title
  
  Hum Pathol
  
  Volume: 44 Issue: 9 Pages: 1780-1788
- DOI
  10.1016/j.humpath.2012.12.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590415, KAKENHI-PROJECT-24590452
[Journal Article] High expression of L-type amino-acid transporter 1(LAT1) in gastric carcinomas : comparison with non-cancerous lesions2011
- Author(s)
  Ichinoe, M., Mikami, T., Yoshida, T., Igawa, I., Tsuruta, T., Nakada, N., Anzai, N., Suzuki, Y., Endou, H., Okayasu, I
- Journal Title
  
  Pathol Int
  
  Volume: 61(5) Pages: 281-289
- NAID
  10031185084
- Data Source
  KAKENHI-PROJECT-21590405
[Journal Article] Cytoglobin expression of rectal subepithelial myofibroblasts : Significant alterations of cytoglobin+stromal cells in long-standing ulcerative colitis2011
- Author(s)
  Okayasu, I., Mikami, T., Yoshida, T., Hana, K., Yokozawa, M., Sada, M., Fujiwara, M., Kawada, N
- Journal Title
  
  Hist Histopathol
  
  Volume: 26 Pages: 679-688
- Data Source
  KAKENHI-PROJECT-21590405
[Journal Article] CITED2 is activated in ulcerative colitis and induces p53-dependent apoptosis in response to butyric acid2011
- Author(s)
  Yoshida, T., et al
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 46 Issue: 3 Pages: 339-349
- DOI
  10.1007/s00535-010-0355-9
- NAID
  10029027845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590405, KAKENHI-PROJECT-23659190
[Journal Article] Cytoglobin expression of rectal subepithelial myofibroblasts: significant alterations of cytoglobin+ stromal cells in long-standing ulcerative colitis.2011
- Author(s)
  Okayasu I, Mikami T, Yoshida T, 他
- Journal Title
  
  Histol Histopathol 26
  
  Pages: 679-688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590353
[Journal Article] Invasive behavior of ulcerative colitis-associated carcinoma is related to reduced expression of CD44 extracellular domain : comparison with sporadic colon carcinoma2011
- Author(s)
  Mikami, T., Yoshida, T., Numata, Y., Kikuchi, M., Araki, K., Nakada, N., Okayasu, I
- Journal Title
  
  Diag Pathol
  
  Volume: 6 Pages: 30-30
- Data Source
  KAKENHI-PROJECT-21590405
[Journal Article] CITED2 is activated in ulcerative colitis and induces p53-dependent apoptosis in responseto butyric acid2011
- Author(s)
  Yoshida, T., et al.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 46(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590405
[Journal Article] CITED2 is activated in ulcerative colitis and induces p53-dependent apoptosis in response to butyric acid2011
- Author(s)
  Yoshida, T., Sekine, T., Aisaki, K., Mikami, T., Kanno, J., Okayasu I
- Journal Title
  
  J Gastroenterol
  
  Volume: 46(3) Pages: 339-349
- NAID
  10029027845
- Data Source
  KAKENHI-PROJECT-21590405
[Journal Article] CITED2 is activated ulcerative colitis and induces p53-dependent apoptosis in response to butyric acid2010
- Author(s)
  Yoshida T, 他4名, Okayasu I.
- Journal Title
  
  J Gastroenterol
  
  Volume: 45(in print)
- NAID
  10029027845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590353
[Journal Article] CITED2 is activated ulcerative colitis and induces p53-dependent apoptosis in response to butyric acid.2010
- Author(s)
  Yoshida T, Sekine T, Aisaki K, Mikami T, Kanno J, Okayasu I.
- Journal Title
  
  J Gastroenterol 46
  
  Pages: 339-349
- NAID
  10029027845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590353
[Journal Article] Appearance of epithelial and stromal genomic instability in background colorectal mucosa of sporadic colorectal cancer patients-relation to age and gender.2009
- Author(s)
  Umeto, H., Yoshida, T., et al.
- Journal Title
  
  Journal of Gastroenterology 44
  
  Pages: 1036-1045
- NAID
  10025581826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590405
[Journal Article] Appearance of epithelial and stromal genomic instability in background colorectal mucosa of sporadic colorectal cancer patients. relation to age and gender2009
- Author(s)
  Umeto, H., Yoshida, T., Araki, K., Yagishita, H., Mikami, T., Okayasu, I
- Journal Title
  
  J Gastroenterol
  
  Volume: 44(10) Pages: 1036-1045
- NAID
  10025581826
- Data Source
  KAKENHI-PROJECT-21590405
[Journal Article] Mucosal remodeling in long-standing ulcerative colitis with colorectal neoplasia : Significant alterations of NCAM plus or alpha-SMA plus subepithelial myofibroblasts2009
- Author(s)
  Okayasu, I., Yoshida, T., et al.
- Journal Title
  
  Pathology International 59
  
  Pages: 707-711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590405
[Journal Article] Mucosal remodeling in long-standing ulcerative colitis with colorectal neoplasia: significant alterations of NCAM+or αSMA+ subepithelial myofibroblasts and interstitial cells.2009
- Author(s)
  Okayasu I, Yoshida T, Mikami T, Hana K, Yokozawa T, Araki K, Mitsuhashi J, Kikuchi M, Adachi E, Sada M.
- Journal Title
  
  Pathol Int 59
  
  Pages: 701-711
- NAID
  10027381791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590353
[Journal Article] Commensal bacteria can enter colonic epithelial cells and induce proinflammatory cytokine secretion : a possible pathogenic mechanism of ulcerative colitis2009
- Author(s)
  Ohkusa, T., Yoshida, T., Sato, N., Watanabe, S., Tajiri, H., Okayasu, I
- Journal Title
  
  J Med Microbiol
  
  Volume: 58(5) Pages: 535-545
- Data Source
  KAKENHI-PROJECT-21590405
[Journal Article] Commensal bacteria can enter colonic epithelial cells and induce proinflammatory cytokine secretion : a possible pathogenic mechanism of ulcerative colitis.2009
- Author(s)
  Ohkusa, T., Yoshida, T., et al
- Journal Title
  
  Journal of Medical Microbiology 58
  
  Pages: 535-545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590405
[Journal Article] Tumor Budding Predicts Lymphatic Involvement and Lymph Node Metastasis in Submucosal Invasive Colorectal Adenocarcinomas and in Non-Polypoid compared with Polypoid Growth2009
- Author(s)
  Ogawa, T., Yoshida. T., et al.
- Journal Title
  
  Scand. J. Gastroenterol. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590346
[Journal Article] Mulcosal remodeling in long-standing ulcerative colitis with colorectal neoplasia2009
- Author(s)
  Okayasu I, Yoshida T, et al.
- Journal Title
  
  Pathol Int 59
  
  Pages: 701-711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590353
[Journal Article] Tumor Budding Predicts Lymphatic Involvement and Lymph NodeMetastasis in Submucosal InvasiveColorectal Adenocarcinomas and inNon-Polypoid compared with PolypoidGrowth2009
- Author(s)
  Ogawa, T, Yoshida, T., Tsuruta, T., Tokuyama, W., Adachi, S., Kikuchi, M. Mikami, T., Saigenji, K., Okayasu, I.
- Journal Title
  
  Scand J Gastroenterol 44
  
  Pages: 605-614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590346
[Journal Article] Mucosal remodeling in long-standing ulcerative colitis with colorectal neoplasia : Significant alterations of NCAM plus or alpha-SMA plus subepithelial myofibroblasts and interstitial cells2009
- Author(s)
  Okayasu I, Yoshida, T., Mikami, T., Hana, K., Yokozawa, M., Araki, K., Mitsuhashi, J., Kikuchi, M., Adachi, E., Sada, M
- Journal Title
  
  Pathol Int
  
  Volume: 59(10) Pages: 701-711
- Data Source
  KAKENHI-PROJECT-21590405
[Journal Article] Epithelial and stromal genetic instability linked to tumor suppressor genes in ulcerative colitis-associated tumorigenesis.2008
- Author(s)
  Yagishita, H., Yoshida, T., et. al.
- Journal Title
  
  Scand J Gastroenterol (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590346
[Journal Article] Epithelial and stromal genetic instabilitylinked to tumor suppressor genes inulcerative colitis-associatedtumorigenesis2008
- Author(s)
  Yagishita, H., Yoshida, T., Ishiguro, K., Numata, Y., Okayasu I.
- Journal Title
  
  Scand J Gastroenterol 43(5)
  
  Pages: 559-566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590346
[Journal Article] Correlation among total colonoscopic findings, clinical Symptoms, and laboratory markers in ulcerative colitis.2008
- Author(s)
  Osada T, Ohkusa T, Oka-yasu I, Yoshida T, et al
- Journal Title
  
  J Gastroenterol Hepatol Suppl 2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590353
[Journal Article] Epithelial and stroma1 genetic instability linked to tumor suppressor genes in ulcerative colitis-associated tumorigenesis2008
- Author(s)
  Yagishita H, Yoshida T, 他2名, Okayasu I
- Journal Title
  
  Scand J Gastroenterol 43
  
  Pages: 559-566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590353
[Journal Article] Establishment of an identification system of bacteria localized in the colonic mucosae of ulcerative colitis patients:comprehensive analysis by sequencing of bacterial 16S rRNA gene from microdissected tissue sections.2007
- Author(s)
  Ishibashi, T., Yoshida, T., et. al.
- Journal Title
  
  Kitasato Med J 37
  
  Pages: 76-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590346
[Journal Article] Low frequency of promoter methylation of O-6-methylguanine DNA methyltransferase (MGMT) and hMLH1 in ulcerative colitis-associated tumors : comparison with sporadic colonic tumors2007
- Author(s)
  Mikami T, Yoshida T, 他5名, Okayasu I
- Journal Title
  
  Am J Clin Pathol (in print)
- Data Source
  KAKENHI-PROJECT-18659102
[Journal Article] Low frequency of promoter methylation of O6-methylguanine DNA methyltransferase and hMLH1 in ulcerative colitis-associated tumors : comparison with sporadic colonic tumors.2007
- Author(s)
  Mikami, T, Yoshida, T., et al.
- Journal Title
  
  American journal Clinical Pathology 127(3)
  
  Pages: 1-8
- Data Source
  KAKENHI-PROJECT-18590346
[Journal Article] Genetic instability on chromosome 17 in the epithelium of non-polypoid colorectal carcinomas compared to polypoid lesions2007
- Author(s)
  Ogawa T, Yoshida T, 他2名, Okayasu I
- Journal Title
  
  Cancer Sci 97・12
  
  Pages: 1335-1342
- NAID
  10020387821
- Data Source
  KAKENHI-PROJECT-18659102
[Journal Article] Establishment of an identification system of bacteria localized in the colonic mucosae of ulcerative colitis patients2007
- Author(s)
  Ishibashi T, Yoshida T, 他2名, Okayasu I.
- Journal Title
  
  Kitasato Med J 37
  
  Pages: 76-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659102
[Journal Article] Establishment of an identification system of bacteria localized in thecolonic mucosae of ulcerativecolitis patients : comprehensiveanalysis by sequencing of bacterial16S rRNA gene from microdissectedtissue sections2007
- Author(s)
  Ishibashi, T., Yoshida, T., Umezawa, A., Ohukusa, T., Okayasu I.
- Journal Title
  
  Kitasato Med J 37(2)
  
  Pages: 76-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590346
[Journal Article] Low frequency of promoter methylation of O-6methylguanine DNA methyltrasfe-rase(MGMT)and hMLH1 in ulcerative colitis-associated tumors2007
- Author(s)
  Mikami T, Yoshida T, 他5名、Okayasu I.
- Journal Title
  
  Am J Clin Pathol 127
  
  Pages: 366-373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659102
[Journal Article] Significant increase of colonic mutated crypts correlates with agein sporadic cancer and diverticulosis cases, with higher ・・・2006
- Author(s)
  Okayasu I, 他6名, Yoshida T, Mikami T
- Journal Title
  
  Cancer Sci 97・5(in press)
- Data Source
  KAKENHI-PROJECT-16590293
[Journal Article] Epithelial and stromal genetic instability contributes to genesis of colorectal adenoma.2006
- Author(s)
  Ishiguro, K, Yoshida, T., et al.
- Journal Title
  
  Gut 55(5)
  
  Pages: 695-702
- Data Source
  KAKENHI-PROJECT-18590346
[Journal Article] Bottom-up cell proliferation with cyclin A and p27^<Kip1> expression in ulcerative colitis-associated dysplasia2006
- Author(s)
  Mikami T, Yoshida T, 他3名, Okayasu I
- Journal Title
  
  Pathol Int 56
  
  Pages: 10-16
- NAID
  10017320958
- Data Source
  KAKENHI-PROJECT-16590293
[Journal Article] Ggenetic instability on chromosome 17 in the epithelium of non-polypoid colorectal carcinomas compared to polypoid lesions.2006
- Author(s)
  Ogawa, T, Yoshida, T., et al.
- Journal Title
  
  Cancer Science 197(12)
  
  Pages: 1335-1342
- Data Source
  KAKENHI-PROJECT-18590346
[Journal Article] Disruption of the p53-p53R2 repair system in ulcerative colitis contributes in colon tumorigenesis2006
- Author(s)
  Yoshida T, 他6名, Okayasu I.
- Journal Title
  
  Int J Cancer 118・6
  
  Pages: 1395-1403
- Data Source
  KAKENHI-PROJECT-18659102
[Journal Article] Epithelial and stromal genetic instability contributes to genesis of colorectal adenomas2006
- Author(s)
  Ishiguro K, Yoshida T, 他2名, Okayasu I
- Journal Title
  
  Gut 55・5
  
  Pages: 695-702
- Data Source
  KAKENHI-PROJECT-18659102
[Journal Article] Disruption of the p53-p53R2 repair system in ulcerative colitis contributes to colon tumorigenesis2006
- Author(s)
  Yoshida T, Haga S, Numata Y, Yamashita K, Mikami T, Ogawa T, Ohkusa T, Okayasu I.
- Journal Title
  
  Int J Cancer 118
  
  Pages: 1395-1403
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590293
[Journal Article] Significant increase of colonic mutated crypts correles with age in sporadic cancer and diverticulosis cases, with higher frequency in the left- than right-side colorectum2006
- Author(s)
  Okayasu I, 他6名, Yoshida T, Mikami T
- Journal Title
  
  Cancer Sci 97・5
  
  Pages: 362-367
- NAID
  10018176767
- Data Source
  KAKENHI-PROJECT-18659102
[Journal Article] Epithelial and stromal genetic instability contributes to genesis of colorectal adenomas2006
- Author(s)
  Ishiguro K, Yoshida T, Yagishita H, Numata Y, Okayasu I.
- Journal Title
  
  Gut (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590293
[Journal Article] Disruption of the p53-p53R2 repair system in ulcerative colitis contributes colon tumorigenesis2006
- Author(s)
  Yoshida T, 他6名, Okayasu I
- Journal Title
  
  Int J Cancer 118
  
  Pages: 1395-1403
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590293
[Journal Article] Bottom-up cell proliferation with cyclin A and p27Kip1 expression in ulcerative colitis-associated dysplasia2006
- Author(s)
  Mikami T, Yoshida T, Shiraishi H, Tokuyama W, Motoori T, Okayasu I.
- Journal Title
  
  Pathol Int 56
  
  Pages: 10-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590293
[Journal Article] Disruption of the p53-p53R2 repair system in ulcerative Colitis Contributes to colon tumorigenesis2006
- Author(s)
  Yoshida T, 他6名, Okuyasu I
- Journal Title
  
  Int J Cancer 118
  
  Pages: 1395-1403
- Data Source
  KAKENHI-PROJECT-16590293
[Journal Article] Epithelial and stromal genetic instability contributes to genesis of colorectal adenomas2006
- Author(s)
  Ishiguro K, Yoshida T, 他3名, Okayasu I
- Journal Title
  
  Gut in press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590293
[Journal Article] Early genetic instability of both epithelial and stromal cells in esophageal squamous cell carcinomas, contrasted with Barrett's adenocarcinomas.2006
- Author(s)
  Shiraishi, H, Mikami, T, Yoshida, T.. et al.
- Journal Title
  
  Journal of Gastroenterology 141(12)
  
  Pages: 1186-1196
- NAID
  10018541381
- Data Source
  KAKENHI-PROJECT-18590346
[Journal Article] Epithelial and stromal genetic instability contributes to genesis of colorectal adenomas2006
- Author(s)
  Ishiguro K, Yoshida T, 他2名, Okayasu I
- Journal Title
  
  Gut (in press)
- Data Source
  KAKENHI-PROJECT-16590293
[Journal Article] Upregulation of p16^<INK4A> and Bax in p53 wild/p53 overexpressing crypts in ulcerative colitis-associated tumors.2004
- Author(s)
  T.Yoshida, et al.
- Journal Title
  
  British Journal of Cancer 91
  
  Pages: 1081-1088
- Data Source
  KAKENHI-PROJECT-15790190
[Journal Article] Upregulation of p16I^<NK4A> and Bax in p53 wild/p53-overexpressing crypts in ulcerative colitis-associated tumours2004
- Author(s)
  Yoshida T, 他3名, Okayasu I
- Journal Title
  
  Br J Cancer 91
  
  Pages: 1081-1088
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590293
[Journal Article] Upregulation of p16^<1NK4A> and Bax in p53wild/p53-overexpressing crypts in ulcerative colitis-associated tumours2004
- Author(s)
  Yoshida T, Matsumoto N, Mikami T, Okayasu I.
- Journal Title
  
  Br J Cancer 91
  
  Pages: 1081-1088
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590293
[Journal Article] Upregulation of p16^<INRA> and Bax in p53 wild/p53-overexpressing crypts in ulcerative colitis-associated tumours2004
- Author(s)
  Yoshida T, Matsumoto N, Mikami T, Okayasu I.
- Journal Title
  
  Br J Cancer 91
  
  Pages: 108-1088
- Data Source
  KAKENHI-PROJECT-16590293
[Journal Article] Disruption of the p53-p53R2 DNA repair system in ulcerative colitis ontributes to colon tumorigenesis.
- Author(s)
  Yoshida, T., et al.
- Data Source
  KAKENHI-PROJECT-18590346
[Presentation] A Novel Preservation Method of Improving DNA Stability for Liquid-Based Cytology Specimens Using a Lung Adenocarcinoma Cell Line.2022
- Author(s)
  Matsuo, Y, Yoshida, T., Yamashita, K., Sonoda, D., Mikubo, M. and Satoh, Y.
- Organizer
  第21回国際細胞学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06911
[Presentation] 核内細胞質封入体様の構造を示し甲状腺腫瘍との鑑別が困難であった副甲状腺腺腫の一例.2022
- Author(s)
  2.坂口忍、太田誠子、横山いさみ、山下和也、梶田咲美乃、一戸昌明、吉田功、三枝信.
- Organizer
  第36回関東臨床細胞学会学術集会/第39回神奈川県臨床細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06911
[Presentation] JSCC-JLCSによる新たな判定基準の提案.2019
- Author(s)
  廣島健三、佐藤之俊、吉田　功、柿沼廣邦、長尾俊孝、松林純、三宅真司、中塚伸一、眞能正幸、竹中明美、元井紀子、澁木康雄、南優子、吉澤明彦、羽場礼次、河原邦光
- Organizer
  第60回日本臨床細胞学会春期大会
- Data Source
  KAKENHI-PROJECT-18K07026
[Presentation] 炎症性バイオマーカーOLFM4からみた炎症性腸疾患関連腫瘍の特異性の解明.2019
- Author(s)
  横山　慧、吉田　功、橋村美紀、三枝　信
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K07026
[Presentation] 日本人胃癌におけるPD-L1発現、MSI status及びEBV陽性評価：多施設共同後方視的観察研究2019
- Author(s)
  吉田　功、小倉豪、田辺美樹子、林大久生、大林千穂、東瑞智、國崎主税、赤澤陽一、小澤壯治、松本壮平、鈴木孝良、美登路昭、福永哲、清水晶子、藤本豪、八尾隆史
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07026
[Presentation] Olfactomedin-4の炎症性腸疾患関連腫瘍発生における役割.2018
- Author(s)
  横山　慧、吉田　功、橋村美紀、三枝　信.
- Organizer
  第107回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K07026
[Presentation] Olfactomedin-4の炎症性腸疾患関連腫瘍発生における役割.2018
- Author(s)
  横山　慧、吉田　功、橋村美紀、三枝　信.
- Organizer
  第107回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-15K08356
[Presentation] 炎症性腸疾患バイオマーカーolfactomedin-4の関連腫瘍発生における役割.2017
- Author(s)
  吉田功、橋口收、橋村美紀、三枝信
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-15K08356
[Presentation] 炎症性腸疾患鑑別診断におけるOLFM4及び上流分子発現検索の有用性.2016
- Author(s)
  吉田　功、永田　匠、橋口　收、鈴木瑞人、橋村美紀、三枝　信
- Organizer
  第105回日本病理学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-15K08356
[Presentation] 潰瘍性大腸炎におけるバイオマーカーolfactomedin 4の発現機序の解明.2016
- Author(s)
  橋口　收、吉田　功、大熊拓也、横田　章、岡安　勲、三枝　信
- Organizer
  第105回日本病理学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-15K08356
[Presentation] 炎症バイオマーカーolfactomedin 4の発現からみた炎症性腸疾患の病因病態.2015
- Author(s)
  横田　章、吉田　功、大熊拓也、橋口　収、三上哲夫、徳山　宣、岡安　勲、三枝　信
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場（名古屋市熱田区）
- Year and Date
  2015-05-01
- Data Source
  KAKENHI-PROJECT-15K08356
[Presentation] 潰瘍性大腸炎におけるバイオマーカーolfactomedin 4の発現機序.2015
- Author(s)
  橋口　収、吉田　功、大熊拓也、横田　章、岡安　勲、三枝　信
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-05-01
- Data Source
  KAKENHI-PROJECT-24590452
[Presentation] 潰瘍性大腸炎バイオマーカーolfactomedin 4の機能同定とその意義.2015
- Author(s)
  大熊拓也、吉田　功、橋口　収、横田　章、岡安　勲、三枝　信
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場（名古屋市熱田区）
- Year and Date
  2015-05-01
- Data Source
  KAKENHI-PROJECT-15K08356
[Presentation] 潰瘍性大腸炎バイオマーカーolfactomedin 4の機能同定とその意義.2015
- Author(s)
  大熊拓也、吉田　功、橋口　収、横田　章、岡安　勲、三枝　信
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-05-01
- Data Source
  KAKENHI-PROJECT-24590452
[Presentation] 潰瘍性大腸炎におけるバイオマーカーolfactomedin 4の発現機序.2015
- Author(s)
  橋口　収、吉田　功、大熊拓也、横田　章、岡安　勲、三枝　信
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場（名古屋市熱田区）
- Year and Date
  2015-05-01
- Data Source
  KAKENHI-PROJECT-15K08356
[Presentation] 炎症バイオマーカーolfactomedin 4の発現からみた炎症性腸疾患の病因病態.2015
- Author(s)
  横田　章、吉田　功、大熊拓也、橋口　収、三上哲夫、徳山　宣、岡安　勲、三枝　信
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-05-01
- Data Source
  KAKENHI-PROJECT-24590452
[Presentation] 潰瘍性大腸炎炎症関連蛋白質OLFM4の炎症における役割2011
- Author(s)
  吉田功, 他
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-04-30
- Data Source
  KAKENHI-PROJECT-21590405
[Presentation] 網羅的解析によって得られたolfactomedin4の潰瘍性大腸炎及び関連腫瘍における役割2010
- Author(s)
  吉田功、宮前結加、沼田賀子、鶴田智子、三上哲夫、岡安勲
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  東京
- Year and Date
  2010-04-27
- Data Source
  KAKENHI-PROJECT-21590405
[Presentation] 網羅的解析によって得られたolfactomedin4の潰瘍性大腸炎及び関連腫瘍における役割2010
- Author(s)
  吉田功, 他
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  東京都京王プラザホテル
- Year and Date
  2010-04-27
- Data Source
  KAKENHI-PROJECT-21590405
[Presentation] 網羅的解析によって得られた01factomedin4の潰瘍性大腸炎及び関連腫瘍における役割2010
- Author(s)
  吉田功, 他4名, 岡安勲
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  東京(京王プラザホテル)
- Year and Date
  2010-04-27
- Data Source
  KAKENHI-PROJECT-20590353
[Presentation] 潰瘍性大腸炎炎症関連蛋白質OLFM4の炎症における役割2010
- Author(s)
  吉田功、三上哲夫、沼田賀子、三枝信、岡安勲
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜
- Year and Date
  2010-04-30
- Data Source
  KAKENHI-PROJECT-21590405
[Presentation] Significance of gene expression and localization in active and inactive ulcerative colitis by comprehensive analysis2009
- Author(s)
  宮前結加、吉田功、岡安勲
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21590405
[Presentation] 大腸癌におけるL型アミノ酸トランスポーター発現亢進の証明2009
- Author(s)
  竹之内一政、吉田功、遠藤仁、岡安勲
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Year and Date
  2009-05-02
- Data Source
  KAKENHI-PROJECT-21590405
[Presentation] 潰瘍性大腸炎発症におけるCITED2-p53系の役割-腸内細菌による新規粘膜上皮細胞死誘導系の可能性2009
- Author(s)
  吉田功、関根司、相崎健一、宮前結加、沼田賀子、三上哲夫、菅野純、岡安勲
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Year and Date
  2009-05-02
- Data Source
  KAKENHI-PROJECT-21590405
[Presentation] 大腸腸内細菌による粘膜上皮性サイトカイン誘導-潰瘍性大腸炎・炎症機序との関連2009
- Author(s)
  丸善明、吉田功、田原あづさ、梅沢敦子、大草敏史、岡安勲
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Year and Date
  2009-05-02
- Data Source
  KAKENHI-PROJECT-18590346
[Presentation] 大腸腸内細菌による粘膜上皮性サイトカイン誘導-潰瘍性大腸炎・炎症機序との関連2009
- Author(s)
  丸善明、吉田功、田原あづさ、梅沢敦子、大草敏史、岡安勲
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Year and Date
  2009-05-02
- Data Source
  KAKENHI-PROJECT-21590405
[Presentation] 潰瘍性大腸炎発症におけるCITED2-p53系の役割-腸内細菌による新規粘膜上皮細胞死誘導系の可能性.2009
- Author(s)
  吉田功, 他
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都国際会館
- Year and Date
  2009-05-02
- Data Source
  KAKENHI-PROJECT-21590405
[Presentation] Significance of gene expression and localization in active and inactive ulcerative colitis by comprehensive analysis2009
- Author(s)
  Miyamae Y, Yoshida T, Okayasu I.
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20590353
[Presentation] 潰瘍性大腸炎発症におけるCITED2-p53系の役割-腸内細菌による新規粘膜上皮細胞死誘導系の可能性2009
- Author(s)
  吉田功、関根司、相崎健一、宮前結加、沼田賀子、三上哲夫、菅野純、岡安勲
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Year and Date
  2009-05-02
- Data Source
  KAKENHI-PROJECT-18590346
[Presentation] Significant decrease of mucosal cytoglobin+ pericryptal myofibroblasts in long-standing ulcerative colitis with colorectal neoplasia, correlatively with α-SMA and HSP47 phenotype expression.2009
- Author(s)
  Okayasu I, Yoshida M, Mikami T, Hana K, Yokozawa M, Sada M, Fujiwara M, Kawada N
- Organizer
  2009 Advances in Inflammatory Bowel Diseases
- Place of Presentation
  Hollywood, USA
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-20590353
[Presentation] 大腸癌におけるL型アミノ酸トランスポーター発現亢進の証明2009
- Author(s)
  竹之内一政、吉田功、遠藤仁、岡安勲
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Year and Date
  2009-05-02
- Data Source
  KAKENHI-PROJECT-18590346
[Presentation] C型肝炎ウイルス感染からの肝発癌におけるゲノム不安定性の果たす役割 : 背景肝病変による差異2008
- Author(s)
  安達滋、吉田功、渋谷明隆、西元寺克禮、岡安勲
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-18590346
[Presentation] 潰瘍性大腸炎in vitroモデルにおける酪酸によるp53活性化機序の解明 : CITED2 の関与2008
- Author(s)
  関根司、吉田功、相崎健一、桐生悠史、大草敏史、菅野純、岡安勲
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-18590346
[Presentation] がんの発生・進展における間質細胞のゲノム不安定性の関与2008
- Author(s)
  吉田功, 岡安勲
- Organizer
  第97回日本病理学会総会・シンポジウム
- Place of Presentation
  金沢市石川県立音楽堂
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-20590353
[Presentation] がんの発生・進展における間質細胞のゲノム不安定性の関与2008
- Author(s)
  吉田功, 岡安勲
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-18590346
[Presentation] がんの発生・進展における間質細胞のゲノム不安定性の関与2008
- Author(s)
  吉田功、岡安勲
- Organizer
  第97回日本病理学会総会、シンポジウム
- Place of Presentation
  金沢市石川県立音楽堂
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-20590353
[Presentation] 潰瘍性大腸炎in vitroモデルにおける酪酸によるp53活性化機序の解明 : CITED2の関与2008
- Author(s)
  関根司, 吉田功, 他
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-18590346
[Presentation] がんの発生・進展における間質細胞のゲノム不安定性の関与2008
- Author(s)
  吉田功、岡安勲
- Organizer
  第97回日本病理学会総会, シンポジウム招待講演
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-18590346
[Presentation] 潰瘍性大腸炎の原因菌探索-細菌16S rRNA遺伝子配列決定法を用いた網羅的解析-2008
- Author(s)
  坂本明良、吉田功、大草敏史、岡安勲
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-18590346
[Presentation] 大腸正常粘膜上皮における癌抑制遺伝メチル化と加齢との相関2008
- Author(s)
  桐生悠史、吉田功、梅戸春江、岡安勲
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-18590346
[Presentation] Occurrence of genomic instabilities in noncancerous colorectal mucosae and its relation with aging and gender2007
- Author(s)
  梅戸春江、吉田功、他
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18590346
[Presentation] Proteomics解析による潰瘍性大腸炎関連癌細胞特異的タンパクの探索 : Sporadic型大腸癌細胞との比較2007
- Author(s)
  荒木香代、三上哲夫、吉田功、山下和也、大石正道、小寺義男、前田忠計、岡安勲
- Organizer
  第96回日本病理学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18590346
[Presentation] Occurrence of genomic instabilities in noncancerous colorectal mucosae and its relation with aging andgender2007
- Author(s)
  梅戸春江、吉田功、岡安勲
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18590346
[Presentation] 潰瘍性大腸炎におけるOLFM4発現誘導機序の解明とその意義.
- Author(s)
  山本渚、吉田功、横田章、岡安勲、三枝信
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590452
[Presentation] 潰瘍性大腸炎腫瘍発生における炎症性バイオマーカーOLFM4の役割
- Author(s)
  吉田功、山本渚、横田章、大熊拓也、岡安勲、三枝信
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-24590452
[Presentation] 炎症性腸疾患バイオマーカーOLFM4発現調節と潰瘍性大腸炎・クローン病の疾患特異性.
- Author(s)
  横田章、吉田功、山本渚、岡安勲、三枝信
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-24590452

1. OKAYASU Isao (20014342)

# of Collaborated Projects: 8 results

# of Collaborated Products: 65 results
2. SAEGUSA Makoto (00265711)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
3. MIKAMI Tetuo (90286352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. KANNO Jun

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 佐藤之俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 内藤雅仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 三窪将史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOSHIDA Tsutomu 吉田 功

吉田 功 ヨシダ ツトム

Research Projects

Research Products

Co-Researchers

がん微小環境・エクソソーム解析による炎症性腸疾患関連腫瘍の病理学的特性解明Principal Investigator

Principal Investigator

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Review Section

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The role of inflammatory biomarker OLMF4 to the malignancy of inflammatory bowel disease related tumorsPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Pathological mechanism of inflammatory bowel disease by inflammatory biomarker OLFM4 inductionPrincipal Investigator

Principal Investigator

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Molecular mechanism of OLFM4 and the significance as an inflammatory biomarker and therapeutic target for ulcerative colitisPrincipal Investigator

Principal Investigator

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Role of CITED2, a novel ulcerative colitis specific gene, to colitis and carcinogenesis.Principal Investigator

Principal Investigator

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Insufficient crosstalk between epithelium and stroma in chronic inflammation-carcinoma sequence: Analysis of a disease model

Principal Investigator

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Analysis of p53-independent inflammatory carcinogenesis in the view of stromal microenvironmental changePrincipal Investigator

Principal Investigator

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網羅的16SrDNA多型性解析による潰瘍性大腸炎原因菌の同定:病変局所からの検索

Principal Investigator

Project Period (FY)

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Research Institution

Mucosal remodeling and genetic instability of stromal cells in ulcerative colitis-associated tumorigenesis

Principal Investigator

Project Period (FY)

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慢性炎症におけるp53依存性DNA修復機構破綻による大腸癌発生機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Genetic instability of stromal cells in ulcerative colitis-associated carcinogenesis

Principal Investigator

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潰瘍性大腸炎における粘膜微細環境の変化と遺伝子異常の蓄積:酸化ストレスによる発癌

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

p53遺伝子・機能異常及びその関連分子解析による潰瘍性大腸炎発癌機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

YOSHIDA Tsutomu 吉田功

吉田功ヨシダツトム