mizoguchi toshihide 溝口利英

… Alternative Names

Researcher Number	90329475
Other IDs
External Links
Affiliation (Current)	2021: 東京歯科大学, 歯学部, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2020: 東京歯科大学, 歯学部, 准教授 2018 – 2019: 東京歯科大学, 歯学部, 講師 2014 – 2018: 松本歯科大学, 総合歯科医学研究所, 講師 2016: 松本歯科大学, 付置研究所, 講師 2006 – 2012: Matsumoto Dental University, Institute of Oral Science, Lecturer, 総合歯科医学研究所, 講師 … More
Review Section/Research Field	Principal Investigator Functional basic dentistry / Biomedical engineering/Biological material science / Medium-sized Section 57:Oral science and related fields / Basic Section 57010:Oral biological science-related Except Principal Investigator Functional basic dentistry / Orthodontic/Pediatric dentistry / Functional basic dentistry / Dental engineering/Regenerative dentistry / Orthodontics/Pediatric dentistry / Basic Section 57040:Regenerative dentistry and dental engineering-related … More
Keywords	Principal Investigator 破骨細胞 / 骨芽細胞 / M-CSF / RANKL / 細胞周期 / ニッチ / NFATc1 / 破骨細胞前駆細胞 / 骨髄間葉系幹細胞 / p38MAPK … More Except Principal Investigator 破骨細胞 / RANKL / 骨芽細胞 / 骨吸収 / OPG / M-CSF / MyD88 / 骨形成 / リポ多糖 / IL-1 / TRIF / マクロファージ / BMP / 破骨細胞前駆細胞 / LPS / アルカリフォスファターゼ / ビスフォスフォネート / CD14 / Wnt5a / Wnt / Osteoclasts / 骨代謝共役 / オステオプロテゲリン / 可溶性RANKL / 異所性骨形成 / MAPキナーゼ / 歯科矯正学 / 歯の移動 / 破骨細胞ニッチ / Smad / Osteoblast / Lipopolysaccharide / 骨誘導因子 / Osteoclast / キトサン / chitosan / ムラミルジペプチド / Nod2 / PGE_2受容体 / TRAM / IL-6 / 骨髄マクロファージ / 骨補填材 / 骨細胞 / 骨リモデリング / Fas / 機械的刺激 / PKC / RANK / Cre recombinase / リバースシグナル / カップリングファクター / 破骨細胞分化阻止因子ODIF / OPG欠損マウス / 異所性骨化 / F4 / 80陽性マクロファージ / 石灰化硬組織 / 破骨細胞分化阻止因子(ODIF) / 活性型ビタミンD_3 / カルシトニン / アクチンリング / 液胞型プロトンポンプ / 吸収窩形成 / バフィロマイシン / 細胞骨格 / アクチンリンング / 吸収窩 / プロトンポンプ / PGE2 / ヒトCD14陽性細胞 / ミノサイクリン / プロスタグランジン / Cox2 / トランスサイトーシス / VGLUT1 / L-グルタミン酸 / 骨粗鬆症 / グルタミン酸 / 骨芽細胞特異的遺伝子欠損 / 骨代謝回転 / 加齢 / 歯槽骨 / コンディショナルノックアウト / 培養装置 / 口腔生化学 / Ｗｎｔ / IL-34 / Ror2 / Wnt非古典経路 / 関節炎 / 脂肪細胞 / 骨髄 / Sfrp5 / QOP / 炎症性サイトカイン / p38MAPキナーゼ / Macrophage / Inflammatory cytokine / p38 MAP kinase / ERK / TNF / Lipopeptide / Toll-like receptor / ビスフォスホネート / 骨髄間質細胞 / 骨代謝共役因子 / サイトカイン / Osteoprotegerin (OPG) / Receptor activator of NF-κB (RANKL) / Bisphosphonate / Coupling / soluble RANKL / ectonic bone formation / ^<60>Coγ線 / 天然高分子 / 滅菌 / 照射 / Co^<60>γ線 / ^<60>Coy-Ray / natural high molecule / sterilization / Irradiation / インターロイキン1 / 樹状細胞 / p38MAPK / Lipopolysaccharide (LPS) / osteoclast / Muramyl dipeptide (MDP) / PGE_2 receptor / マウス / 自然免疫 / TLR4 / bone marrow macrophage / mouse / 骨 / ハイドロキシアパタイト / 骨伝導 / キチン / キチン・キトサン / ハイドロキシアパタト / 骨置換材 / bone filling material / bone / hydroxyapatite / bone conduction / 機械刺激 / 細胞死 / エストロゲン受容体 / タモキシフェン / プロスタグランジンE_2 / RAW264.7 / NF-κB / p38 MAPK / osteocyte / mechanical stress / apotosis / bone remodeling / estrogen receptor / tamoxifen / osteoblast / I型コラーゲン / プロトカドヘリン / ウマ歯冠 / セメント質 / EDTA可溶画分 / EDTA可溶 / 特異的タンパク質 / EDTA抽出 / 二次元電気泳動 / 免疫反応 / Cementum / EDTA soluble fraction / horse teeth / Type I Collagen / Protocadherin / ヒト破骨細胞 / 歯周疾患 / 破骨細胞分化因子 / ペプチドグリカン / 延命 / 酵母ツーハイブリッド / p38 MAPキナーゼ / MKK6 / アデノウイルスベクター / osteoclasts / MAP kinase / bone resorption / survival / Yeast Two Hybrid Screening / 細胞周期停止破骨前駆細胞 / Fos欠損マウス / 骨髄細胞マクロファージ / RANK-Cre / プロモデオキシウリジン / Osteoblasts / Cell cycle-arrested quiescent osteoclast precursor / Osteoclast niche / Fos deficient mice / Creリコンビナーゼ / 歯周組織 / ノックインマウス / COX2 / BACクローン / 相同組み換え / orthodontics / osteoclast precursors / 歯髄細胞 / 石灰化 / 骨髄細胞 / 骨髄間葉細胞 / BMP-2 / アルカリホスファターゼ / オステオカルシン / リン酸トランスポーター / 石灰化メカニズム / スクレロスチン / 白血病抑制因子 / 歯周病 / Gli1 / 歯髄幹細胞 / Autophagy / Beclin1 / 矯正力 / オートファジー / Beclin 1 / LC3B / TRAF6 / 生体活性 / リン酸カルシウム / 再生医療 / 象牙芽細胞 / 細胞分化 / 細胞膜センサータンパク質 / TRPM7 / 骨格形成 / ミネラル輸送 / キナーゼ活性 / 骨髄間葉系細胞 / 変形性顎関節症 / 性ホルモン / ANGPTL-7 / CAR-1 / スフェロイド / 間葉系幹細胞 / stemness / インテグリン / 自発的 / 体細胞 / 脱分化 Less

Identification of novel dental pulp stem cells and analysis of their regulatory mechanisms of differentiationPrincipal InvestigatorOngoing
- Principal Investigator
  
  溝口利英
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Tokyo Dental College
性ホルモンと機械的刺激による変形性顎関節症の病態発生機序の解明とその治療戦略Ongoing
- Principal Investigator
  
  石井武展
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tokyo Dental College
象牙芽細胞の機能と分化を制御するマルチシグナルを標的とする象牙質再生創薬基盤確立Ongoing
- Principal Investigator
  
  渋川義幸
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Tokyo Dental College
破骨細胞が制御する骨髄老化機構の解明と造血機能の若返りへの応用Principal InvestigatorOngoing
- Principal Investigator
  
  溝口利英
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Tokyo Dental College
チャネルキナーゼTRPM7による骨格形成制御機構の解明Ongoing
- Principal Investigator
  
  岡部幸司
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Fukuoka Dental College
Mechanism of stemness regulation of mesenchymal stem cells on spheroid formationOngoing
- Principal Investigator
  
  李憲起
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Matsumoto Dental University
A study on bioactive ceramic biomaterialsOngoing
- Principal Investigator
  
  鈴木治
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Tohoku University
Analysis of osteoclast precursor niche regulated by mesenchymal stem cells(Fostering Joint International Research)Principal Investigator
- Principal Investigator
  
  Mizoguchi Toshihide
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo Dental College
  Matsumoto Dental University
Analysis of reparative dentin formation regulated by dental pulp stem cells using a fate mapping approachPrincipal Investigator
- Principal Investigator
  
  Mizoguchi Toshihide
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo Dental College
  Matsumoto Dental University
Applied research of periodontal disease therapeutics using osteogenic sugnal from osteoclasts
- Principal Investigator
  
  Udagawa Nobuyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Roles Gli1-positive dental pulp stem cells during dentin regeneration
- Principal Investigator
  
  Hosoya Akihiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Health Sciences University of Hokkaido
  Matsumoto Dental University
Dose orthodontic force induce autophagy of osteoclast precursor ?
- Principal Investigator
  
  Arai Atsushi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
A study on the usefulness of human dental pulp cells in hard tissue regeneration
- Principal Investigator
  
  Nakamura Midori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
Analysis of osteoclast precursor niche regulated by BM-MSCPrincipal Investigator
- Principal Investigator
  
  Mizoguchi Toshihide
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
How is the formation site of osteoclasts determined?
- Principal Investigator
  
  Takahashi Naoyuki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Hematopoietic cells regulate bone metabolism
- Principal Investigator
  
  KOBAYASHI Yasuhiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
Analysis of osteoclast niche regulated by Wnt signals.
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Analysis of the regulation of bone metabolism by the pool of osteoclast precursorsPrincipal Investigator
- Principal Investigator
  
  MIZOGUCHI Toshihide
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Analysis of roles of Wnt5a in alveolar bone remodeling, and their application for orthodontic tooth movement.
- Principal Investigator
  
  KOBAYASHI Yasuhiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
破骨細胞培養系における非侵襲的細胞回収用装置の開発と応用
- Principal Investigator
  
  穴田貴久
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Tohoku University
Analysis of molecular mechanism of carbon nanotube regulating bone metabolismPrincipal Investigator
- Principal Investigator
  
  MIZOGUCHI Toshihide
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Functional basic dentistry
  Biomedical engineering/Biological material science
- Research Institution
  Matsumoto Dental University
Identification of osteoclast niches regulatory factor produced by osteoblastsPrincipal Investigator
- Principal Investigator
  
  MIZOGUCHI Toshihide
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Elucidation of the regulated mechanism of bone metabolism by osteoclastic transcytosis.
- Principal Investigator
  
  UDAGAWA Nobuyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Analysis of novel MAP kinase binding factor which regulates osteoclasts
- Principal Investigator
  
  YAMASHITA Teruhito
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
ヒト造血系細胞再構成マウスを用いた歯槽骨リモデリング機構の解析
- Principal Investigator
  
  小林泰浩
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
造血ニッチが維持する破骨細胞前駆細胞の性質Principal Investigator
- Principal Investigator
  
  溝口利英
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
The relationship between cell proliferation and RANKL-induced osteoclastogenesis
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Application of Cre-loxP system for elucidation of mechanisms in bone remodeling during tooth movement
- Principal Investigator
  
  KOBAYASHI Yasuhiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
Establishment of periodontitis treatment method by inhibition of RANK-Toll like receptor signal
- Principal Investigator
  
  UDAGAWA Nobuyuki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Analysis of p38 MAP kinase pathway in osteoclasts
- Principal Investigator
  
  YAMASHITA Teruhito
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
破骨細胞によるビスフォスホネートの特異的取り込み機構の解析
- Principal Investigator
  
  宮沢裕夫
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
破骨細胞の骨吸収を制御するSNARE蛋白の役割の解明Principal Investigator
- Principal Investigator
  
  溝口利英
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
破骨細胞分化阻止因子(ODIF)のクローニングと生理的役割の解析
- Principal Investigator
  
  高橋直之
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Signal transduction of RANK and Toll-like receptor in alveolar bone destruction
- Principal Investigator
  
  UDAGAWA Nobuyuki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Study on mechanical properties and invivo of bone filling materials with chitosan as a bonding agent which had net structure
- Principal Investigator
  
  ITO Michio
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  補綴理工系歯学
- Research Institution
  Matsumoto Dental University
The establishment of inducible osteocyte ablation mouse model to elucidate the mechanisms of maxillo-mandibular dysmorphia.
- Principal Investigator
  
  HOSOYA Akihiro, 小林泰浩
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
Determination of Cementum Specific Proteins in Horse Molar Teeth
- Principal Investigator
  
  FUKASAWA Kayoko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Signal transduction and cell-to-cell communication in the bone resorption induced by inflammation
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
骨芽細胞及びリンパ球の分化を促進する破骨細胞由来新規サイトカインの同定
- Principal Investigator
  
  UDAGAWA Nobuyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
  Showa University
Analysis of signal transduction of osteoclast differentiation factor (RANKL) in alveolar bone destruction
- Principal Investigator
  
  UDAGAWA Nobuyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Study on mechanism of the coupling between bone resorption and bone formation
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Changes of properties of Chitosan film by ^<60>Coy-Ray Irradiation
- Principal Investigator
  
  ITO Michio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  補綴理工系歯学
- Research Institution
  Matsumoto Dental University
Analysis of signal transduction of inflammatory cytokines in bone destruction
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  MATSUMOTO DENTAL UNIVERSITY
  Showa University

[Book] 骨ﾍﾟﾃﾞｨｱ　骨疾患・骨代謝キーワード辞典日本骨代謝学会編、骨芽細胞と造血幹細胞2015
- Author(s)
  溝口利英、小林泰浩、中道裕子
- Total Pages
  327
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-26462826
[Journal Article] VDR in osteoblast-lineage cells primarily mediates vitamin D treatment-induced increase in bone mass by suppressing bone resorption2017
- Author(s)
  Nakamichi Y, Udagawa N, Horibe K, Mizoguchi T, Yamamoto Y, Nakamura T, Hosoya A, Kato S, Suda T, Takahashi N
- Journal Title
  
  Journal of Bone and Mineral Research
  
  Volume: 32 Pages: 1297-1308
- DOI
  10.1002/jbmr.3096
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-26462826, KAKENHI-PROJECT-16K11493, KAKENHI-PROJECT-16K11664, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-15KK0356, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-17H04374, KAKENHI-PROJECT-15K11093
[Journal Article] Characterization of bone marrow mesenchymal sten cells2017
- Author(s)
  Mizoguchi, T.
- Journal Title
  
  Clin Calcium
  
  Volume: 27 Pages: 779-787
- Data Source
  KAKENHI-PROJECT-17H04374
[Journal Article] The W9 peptide directly stimulates osteoblast differentiation via RANKL signaling2017
- Author(s)
  Nakamura, M., Nakamichi, Y., Mizoguchi, T., Koide, M., Yamashita, T., Ara, T., Nakamura, H., Penninger, JM., Furuya, Y., Yasuda, H., and Udagawa, N.
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 59 Pages: 146-151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04374
[Journal Article] The W9 peptide directly stimulates osteoblast differentiation via RANKL signaling.2017
- Author(s)
  Nakamura M, Nakamichi Y, Mizoguchi T, Koide M, Yamashita T, Ara T, Nakamura H, Penninger JM, Furuya Y, Yasuda H and Udagawa N
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 59 Pages: 146-151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05508
[Journal Article] The W9 peptide directly stimulates osteoblast differentiation via RANKL signaling.2017
- Author(s)
  Nakamura M, Nakamichi Y, Mizoguchi T, Koide M, Yamashita T, Ara T, Nakamura H, Penninger JM, Furuya Y, Yasuda H and Udagawa N
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 59 Pages: 146-151
- Data Source
  KAKENHI-PROJECT-15K11377
[Journal Article] Osteogenic factor Runx2 marks a subset of leptin receptor-positive cells that sit atop the bone marrow stromal cell hierarchy2017
- Author(s)
  Yang Mengyu、Arai Atsushi、Udagawa Nobuyuki、Hiraga Toru、Lijuan Zhao、Ito Susumu、Komori Toshihisa、Moriishi Takeshi、Matsuo Koichi、Shimoda Kouji、Zahalka Ali H.、Kobayashi Yasuhiro、Takahashi Naoyuki、Mizoguchi Toshihide
- Journal Title
  
  Sci Rep
  
  Volume: 7 Pages: 4298-4298
- DOI
  10.1038/s41598-017-05401-1
- NAID
  120006576162
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11798, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-26221310, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-17H04374, KAKENHI-PROJECT-15K11028, KAKENHI-PROJECT-15K11048, KAKENHI-PROJECT-15K11093, KAKENHI-PROJECT-16K15781
[Journal Article] The dynamin inhibitor dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts2016
- Author(s)
  Thirukonda GJ, Uehara S, Nakayama T, Yamashita T, Nakamura Y, Mizoguchi T, Takahashi N, Yagami K, Udagawa N, Kobayashi Y.
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 34 Pages: 395-405
- DOI
  10.1007/s00774-015-0683-1
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-26462826, KAKENHI-PROJECT-15K11059, KAKENHI-PROJECT-16K11664
[Journal Article] Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance.2016
- Author(s)
  Ito K, Turcotte R, Cui J, Zimmerman SE, Pinho S, Mizoguchi T, Arai F, Runnels JM, Alt C, Teruya-Feldstein J, Mar JC, Singh R, inkel T, Suda T, Lin CP, Frenette PS, Ito K
- Journal Title
  
  Science
  
  Volume: 354(6316) Pages: 1156-1160
- DOI
  10.1126/science.aaf5530
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26293228, KAKENHI-PROJECT-26462826
[Journal Article] Comparing immunocompetent and immunodeficient mice as animal models for bone tissue engineering.2015
- Author(s)
  Zhang Y, Li X, Chihara T, Mizoguchi T, Hori A, Udagawa N, Takahashi N, Nakamura H, Hasegawa H, Taguchi A, Shinohara A, Kagami H
- Journal Title
  
  Oral Dis
  
  Volume: 21 Pages: 583-592
- DOI
  10.1111/odi.12319
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11092, KAKENHI-PROJECT-26462826, KAKENHI-PROJECT-15K15688, KAKENHI-PROJECT-25293416
[Journal Article] Bone cell biology assessed by microscopic approach. Mechanisms of in vivo osteoclastogenesis.2015
- Author(s)
  Mizoguchi T.
- Journal Title
  
  Clin Calcium
  
  Volume: 25 Pages: 1445-1452
- Data Source
  KAKENHI-PROJECT-26462826
[Journal Article] Tetracyclines Convert the Osteoclastic-Differentiation Pathway of Progenitor Cells To Produce Dendritic Cell-like Cells2012
- Author(s)
  Kinugawa S et al.
- Journal Title
  
  J Immunology
  
  Volume: 188 Pages: 1772-1781
- DOI
  10.4049/jimmunol.1101174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22792102, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23792492, KAKENHI-PROJECT-24592786
[Journal Article] Tetracyclines convert the osteoclastic-differentiation pathway of progenitor cells to produce dendritic cell-like cells2012
- Author(s)
  Kinugawa S(1), Mizoguchi T(4), (他9名)
- Journal Title
  
  J Immunol
  
  Volume: 188 Pages: 1772-1781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791804
[Journal Article] Nishita M, Marumo K, Martin TJ, Minami Y, Takahashi NWnt5a-Ror2 signaling betweenosteoblast-lineage cells and osteoclast precursors enhancesosteoclastgenesis.2012
- Author(s)
  Maeda, K., Kobayashi, Y., Udagawa, N., Uehara, S., Ishihara, A., Mizoguchi, T., Kikuchi, Y., Takada, I., Kato, S., Kani, S., Nishita, M., Marumo, K., Martin, T.J., Minami, Y., Takahashi, N.
- Journal Title
  
  Nat Med.
  
  Volume: (印刷中) Pages: 405-12
- DOI
  10.1038/nm.2653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390080, KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551, KAKENHI-PUBLICLY-22021039, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22790291, KAKENHI-PLANNED-23112007, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-23650595, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23791662, KAKENHI-PROJECT-23791668, KAKENHI-PROJECT-23792134, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24659833
[Journal Article] Daily administration of eldecalcitol (ED-71), an active vitamin D analog, increases bone mineral density by suppressing RANKL expression in mouse trabecular bone.2012
- Author(s)
  Harada S et al.
- Journal Title
  
  J. Bone Miner. Res.
  
  Volume: 27 Pages: 461-473
- DOI
  10.1002/jbmr.555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22791804, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23792135
[Journal Article] Daily administration of eldecalcitol(ED-71), an active vitamin D analog, increase bone mineral density by suppressing RANKL expression in mouse trabecular bone2012
- Author(s)
  Harada S(1). Mizoguchi T(equal contribution)(2), (他9名), Kobayashi Y, Nakamichi Y, Takeda S, Takahashi F, Saito H, Yasuda H, Udagawa N, Suda T, Takahashi N.
- Journal Title
  
  J Bone Miner Res
  
  Volume: 27 Pages: 461-473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791804
[Journal Article] Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis.2012
- Author(s)
  Maeda K, Kobayashi Y (2), Mizoguchi T (6).
- Journal Title
  
  Nat Med
  
  Volume: 18 Pages: 405-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659972
[Journal Article] Daily administration of eldecalcitol (ED-71), an active vitamin D analog, increases bone mineral density by suppressing RANKL expression in mouse trabecular bone.2012
- Author(s)
  Harada S, Mizoguchi T, Kobayashi Y, Nakamichi Y, Takeda S, Sakai S, Takahashi F, Saito H, Yasuda H, Udagawa N, Suda T, Takahashi N.
- Journal Title
  
  J Bone Miner Res
  
  Volume: 27 Pages: 461-473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659972
[Journal Article] c-Fos plays an essential role in theup-regulation of RANK expression in osteoclast precursors within the bone microenvironment.2012
- Author(s)
  Arai A, Mizoguchi T, Harada S, Kobayashi Y, Nakamichi Y, Yasuda H, Penninger JM, Yamada K, Udagawa N, Takahashi N.
- Journal Title
  
  J Cell Sci
  
  Volume: 125 Pages: 2910-2917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659972
[Journal Article] c-Fos plays an essential role in the up-regulation of RANK expression in osteoclast precursors within the bone microenvironment2012
- Author(s)
  Arai A, Mizoguchi T(他8名)
- Journal Title
  
  J Cell Sci
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791804
[Journal Article] c-Fos plays an essential role in the up-regulation of RANK expression in osteoclast precursors within the bone microenvironment2012
- Author(s)
  Arai A et al.
- Journal Title
  
  J Cell Sci. Feb;
  
  Volume: 125 Pages: 2910-17
- DOI
  10.1242/jcs.099986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22791804, KAKENHI-PROJECT-23792135, KAKENHI-PROJECT-23792455, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24659833
[Journal Article] Lineage-committed osteoclast precursors circulate in blood and settle down into bone.2012
- Author(s)
  Muto, A, Mizoguchi, T, Udagawa, N., Ito, S, Kawahara, I, Abiko, Y, Arai, A., Harada, S., Kobayashi, Y., Nakamichi, Y, Penninger, JM, Noguchi, T, Takahashi, N.
- Journal Title
  
  J Bone MinerRes.Dec;
  
  Volume: 26 Pages: 2978-2990
- DOI
  10.1002/jbmr.490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390497, KAKENHI-PROJECT-21390498, KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390550, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-21592615, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-23593074, KAKENHI-PROJECT-23792135, KAKENHI-PROJECT-23792455, KAKENHI-PROJECT-23792492
[Journal Article] Wnt による破骨細胞の分化制御機構2012
- Author(s)
  Shimizu M, Kobayashi Y, Mizoguchi T, Nakamura H, Kawahara I, Narita N, Usui Y, Aoki K, Hara K, Haniu H, Ogihara N, Ishigaki N, Nakamura K, Kato H, Kawakubo M, Dohi Y, Taruta S, Kim YA, Endo M, Ozawa H, Udagawa N, Takahashi N, Saito N
- Journal Title
  
  細胞
  
  Volume: 24 Pages: 2176-2185
- DOI
  10.1002/adma.201103832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002007, KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22791804, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-24659833
[Journal Article] Carbon Nanotubes Induce Bone Calcification by Bidirection with Osteoblasts2012
- Author(s)
  Shimizu M(1), Mizoguchi T(3), (他20名)
- Journal Title
  
  Adv Mater
  
  Volume: 24 Pages: 2176-2185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791804
[Journal Article] Polarized osteoclasts put marks tartrate-resistant acid phosphatase on dentin slices; A simple method for identifying polarized osteoclasts.2012
- Author(s)
  Nakayama T, et al
- Journal Title
  
  Bone
  
  Volume: 49 Pages: 1331-1339
- DOI
  10.1016/j.bone.2011.09.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21592378, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22791804, KAKENHI-PROJECT-23792134
[Journal Article] Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis2012
- Author(s)
  Maeda K(1), Mizoguchi T(6), (他13名)
- Journal Title
  
  Nat Med
  
  Volume: 18 Pages: 405-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791804
[Journal Article] Spleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in CSF-1^<op/op>mice2012
- Author(s)
  Nakamichi Y et al.
- Journal Title
  
  PNAS. Jun
  
  Volume: 109 Pages: 10006-1
- DOI
  10.1073/pnas.1207361109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23792135, KAKENHI-PROJECT-23792455, KAKENHI-PROJECT-24659833
[Journal Article] c-Fos plays an essential role in the up-regulation of RANK expression in osteoclast precursors within the bone microenvironment2012
- Author(s)
  Arai A, Mizoguchi T, Harada S, Kobayashi Y, Nakamichi Y, Yasuda H, Penninger JM, Yamada K, Udagawa N, Takahashi N
- Journal Title
  
  J. Cell Sci
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390551
[Journal Article] Polarized osteoclasts put marks of tartrate-resistant acid phosphatase on dentin slices-A simple method for identifying polarized osteoclasts2011
- Author(s)
  Nakayama T(1). Mizoguchi T(2), (他10名)
- Journal Title
  
  Bone
  
  Volume: 49 Pages: 1331-1339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791804
[Journal Article] Polarized osteoclasts put marks of tartrate-resistant acid phosphatase on dentin slices-a simple method for identifying polarized osteoclasts2011
- Author(s)
  Nakayama T, Mizoguchi T, Uehara S, Yamashita T, Kawahara I, Kobayashi Y, Moriyama Y, Kurihara S, Sahara N, Ozawa H, Udagawa N, Takahashi N
- Journal Title
  
  Bone
  
  Volume: 49 Pages: 1331-1339
- URL
  http://dx.doi.org/10.1016/j.bone.2011.09.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390551
[Journal Article] Frontiers in Vitamin D ; Basic Research and Clinical Application. Inhibitory Effects of Eldecalcitol, an Active Vitamin D Derivative, on Bone Resorption in Vivo2011
- Author(s)
  Harada S(1), Mizoguchi T(2), (他1名)
- Journal Title
  
  Clin Calcium
  
  Volume: 11 Pages: 1675-1682
- Data Source
  KAKENHI-PROJECT-22791804
[Journal Article] Lineage-committed osteoclast precursors circulating in blood and settle down into bone2011
- Author(s)
  Muto M(1). Mizoguchi T(equal contribution)(2), (他11名)
- Journal Title
  
  J Bone Miner Res
  
  Volume: 26 Pages: 2978-2990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791804
[Journal Article] RANKL signaling and bone diseases. Quiescent osteoclast precursors and RANKL signaling2011
- Author(s)
  Mizoguchi T.
- Journal Title
  
  Clin Calcium
  
  Volume: 8 Pages: 1187-1192
- Data Source
  KAKENHI-PROJECT-22791804
[Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2010
- Author(s)
  Takahashi N(1), Mizoguchi T(4), (他2名)
- Journal Title
  
  Adv Exp Med Biol. 658
  
  Pages: 21-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791365
[Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2010
- Author(s)
  Takahashi N, Muto A, Arai A, Mizoguchi T
- Journal Title
  
  Adv Exp Med Biol
  
  Volume: 658 Pages: 21-30
- DOI
  10.1007/978-1-4419-1050-9_3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390351
[Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo2010
- Author(s)
  Takahashi N(1), Muto A, Arai A, Mizoguchi T(4).(他2名)
- Journal Title
  
  Adv Exp Med Biol
  
  Volume: 658 Pages: 21-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791804
[Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2010
- Author(s)
  Takahashi N, Mizoguchi T
- Journal Title
  
  Adv Exp Med Biol. 658
  
  Pages: 21-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200019
[Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2009
- Author(s)
  Mizoguchi T, Muto A, Udagawa N, Arai A, Yamashita T, Hosoya A, Ninomiya T, Nakamura H, Yamamoto Y, Kinugawa S, Nakamura M, Nakamichi Y, Kobayashi Y, Nagasawa S, Oda K, Tanaka H, Tagaya M, Penninger JM, Ito M, Takahashi N
- Journal Title
  
  J Cell Biol 184
  
  Pages: 541-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592163
[Journal Article] Docetaxel inhibits bone resorption through suppression of osteoclast formation and function in different manners.2009
- Author(s)
  Takahashi M, Mizoguchi T, Uehara S, Nakamichi Y, Yang S, Naramoto H, Yamashita T, Kobayashi Y, Yamaoka M, Furusawa K, Udagawa N, Uematsu T, Takahashi N
- Journal Title
  
  J Bone Miner Metab 27
  
  Pages: 24-35
- NAID
  10025336084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592163
[Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2009
- Author(s)
  Mizoguchi T, Muto A, Udagawa N et al.
- Journal Title
  
  J Cell Biol 184
  
  Pages: 541-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390476
[Journal Article] Multiwalled carbon nanotubes specifically inhibit osteoclast differentiation and function.2009
- Author(s)
  Narita N, Nakamura H, Mizoguchi T, Ozawa H, Udagawa N, Takahashi N
- Journal Title
  
  Nano Lett. 9
  
  Pages: 1406-1413
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200019
[Journal Article] 骨細胞によるリン代謝調節機構2009
- Author(s)
  溝口利英
- Journal Title
  
  腎と骨代謝 22
  
  Pages: 281-288
- Data Source
  KAKENHI-PROJECT-20200019
[Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2009
- Author(s)
  Mizoguchi T, et al.
- Journal Title
  
  J Cell Biol 184
  
  Pages: 541-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390476
[Journal Article] Diphenylhydantoin inhibits osteoclast differentiation and function through suppression of NFATc1 signaling.2009
- Author(s)
  Koide M(1), Mizoguchi T(4), (他9名)
- Journal Title
  
  J Bone Miner Res. 24
  
  Pages: 1469-1480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791365
[Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2009
- Author(s)
  Mizoguchi T, et al.
- Journal Title
  
  J Cell Biol 184
  
  Pages: 541-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592163
[Journal Article] Docetaxel inhibits bone resorption through suppression of osteoclast formation and function different manners.2009
- Author(s)
  Takahashi M, Mizoguchi T, Nakamichi Y, Yamashita T, Udagawa N, Takahashi N
- Journal Title
  
  J. Bone Miner. Metab. 27
  
  Pages: 24-35
- NAID
  10025336084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200019
[Journal Article] 生体内における破骨細胞形成部位決定機構の解析-細胞周期の停止した破骨細胞前駆細胞(QOP)の同定-2009
- Author(s)
  溝口利英
- Journal Title
  
  THE BONE 23
  
  Pages: 121-126
- Data Source
  KAKENHI-PROJECT-20200019
[Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2009
- Author(s)
  Mizoguchi T(1), (他19名)
- Journal Title
  
  J Cell Biol. 184
  
  Pages: 541-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791365
[Journal Article] Diphenylhydantoin inhibits osteoclast differentiation and function through suppression of NFATc1 signaling.2009
- Author(s)
  Koide M, Nynomiya T, Mizoguchi T, Yamashita T, Nakamura H, Takahashi N, Udagawa N
- Journal Title
  
  J Bone Miner Res. 24
  
  Pages: 1469-1480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200019
[Journal Article] 骨細胞によるリン代謝調節機構2009
- Author(s)
  溝口利英
- Journal Title
  
  腎と骨代謝 22
  
  Pages: 281-288
- Data Source
  KAKENHI-PROJECT-20791365
[Journal Article] 生体内における破骨細胞形成部位決定機構の解析-細胞周期の停止した破骨細胞前駆細胞(QOP)の同定-2009
- Author(s)
  溝口利英
- Journal Title
  
  THE BONE 23
  
  Pages: 121-126
- Data Source
  KAKENHI-PROJECT-20791365
[Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2009
- Author(s)
  Mizoguchi T, Udagawa N, Yamashita T, Hosoya A, Ninomiya T, Nakamichi Y, Takahashi N
- Journal Title
  
  J Cell Biol. 184
  
  Pages: 541-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200019
[Journal Article] Multiwalled carbon nanotubes specifically inhibit osteoclast differentiation and function.2009
- Author(s)
  Narita N(1), Mizoguchi T(6), (他13名)
- Journal Title
  
  Nano Lett. 9
  
  Pages: 1406-1413
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791365
[Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo2009
- Author(s)
  Toshihide Mizoguchi
- Journal Title
  
  J. Cell Biol 184
  
  Pages: 541-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791365
[Journal Article] Docetaxel inhibits bone resorption through suppression of osteoclast formation and function different manners.2009
- Author(s)
  Takahashi M(1), Mizoguchi T(2), (他11名)
- Journal Title
  
  J. Bone Miner. Metab. 27
  
  Pages: 24-35
- NAID
  10025336084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791365
[Journal Article] MKK6-p38 MAPK signaling pathway enhances survival but not bone-resorbing activity of osteoclasts.2008
- Author(s)
  Yamashita T, Kobayashi Y, Mizoguchi T, Yamaki M, Miura T, Tanaka S, Udagawa N, Takahashi N
- Journal Title
  
  Biochem Biophys Res Commun 365
  
  Pages: 252-257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592163
[Journal Article] 骨芽細胞/ストローマ細胞が支持する破骨細胞ニッチ2008
- Author(s)
  溝口利英
- Journal Title
  
  腎と骨代謝 21
  
  Pages: 47-52
- Data Source
  KAKENHI-PROJECT-18791376
[Journal Article] MKK6-p38 MAPK signaling pathway enhances survival but not bone-resorbing activity of osteoclasts.2008
- Author(s)
  Yamashita T(1), Mizoguchi T(3), (他6名)
- Journal Title
  
  Biochem Biophys. Res. Commun. 365
  
  Pages: 252-257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791365
[Journal Article] Nonlinear stress analysis of titanium implants by finite element method.2008
- Author(s)
  Nagasawa S(1), Mizoguchi T(6), (他10名)
- Journal Title
  
  Dent Mater J. 4
  
  Pages: 633-639
- NAID
  110006861875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791365
[Journal Article] 目で見るbone Biology(第十回骨芽細胞と幹細胞ニッチ)2007
- Author(s)
  溝口利英
- Journal Title
  
  骨粗鬆症治療 (in press)
- Data Source
  KAKENHI-PROJECT-18791376
[Journal Article] 骨芽細胞と幹細胞ニッチ.2007
- Author(s)
  溝口利英
- Journal Title
  
  骨粗鬆症治療 6
  
  Pages: 98-101
- Data Source
  KAKENHI-PROJECT-18791376
[Journal Article] Coordination of microtubules ant the actin cytoskeleton is important in osteoclast function, but calcitonin disrupts sealing zones without affecting microtubule networks.2006
- Author(s)
  Mizoguchi T et al.
- Journal Title
  
  Bone 39・(4)
  
  Pages: 684-693
- Data Source
  KAKENHI-PROJECT-18390557
[Journal Article] Coordination of microtubules ant the actin cytoskeleton is important In osteoclast function, but calcitonin disrupts sealing zones without affecting microtubule networks.2006
- Author(s)
  Mizoguchi T et al.
- Journal Title
  
  Bone 39・(4)
  
  Pages: 684-693
- Data Source
  KAKENHI-PROJECT-18659618
[Journal Article] Dolomite supplementation improves bone metabolism through modulation of calcium-regulating hormone secretion in ovariectomized rats.2005
- Author(s)
  Mizoguchi T et al.
- Journal Title
  
  J Bone Miner Metab (in press)
- Data Source
  KAKENHI-PROJECT-16791139
[Journal Article] Dolomite supplementation improves bone metabolism through modulation of calcium-regulating hormone secretion in ovariectomized rats.2005
- Author(s)
  Mizoguchi T
- Journal Title
  
  J Bone Miner Metab 23・2
  
  Pages: 140-146
- Data Source
  KAKENHI-PROJECT-17591955
[Journal Article] Dolomite supplementation improves bone metabolism through modulation of calcium-regulating hormone secretion in ovariectomized rats.2005
- Author(s)
  Mizoguchi T
- Journal Title
  
  J Bone Miner Metab 23・2
  
  Pages: 140-146
- Data Source
  KAKENHI-PROJECT-16791139
[Journal Article] Dolomite supplementation improves bone metabolism through modulation of calcium-regulating hormone secretion in ovariectomized rats.2005
- Author(s)
  Mizoguchi T et al.
- Journal Title
  
  J Bone Miner Metab (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390641
[Journal Article] 目で見るbone Biology(第一回破骨細胞分化と機能調節機構)2005
- Author(s)
  溝口利英他
- Journal Title
  
  骨粗鬆症治療 4・1
  
  Pages: 3-6
- Data Source
  KAKENHI-PROJECT-16791139
[Journal Article] Dolomite supplementation improves bone metabolism through modulation of calcium-regulating hormone secretion in ovariectomized rats.2005
- Author(s)
  Mizoguchi T, et al.
- Journal Title
  
  J Bone Miner Metab 23
  
  Pages: 140-146
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390565
[Journal Article] 目で見るbone Biology(第二回骨芽細胞分化と機能調節機構)2005
- Author(s)
  溝口利英他
- Journal Title
  
  骨粗鬆症治療 4・2(in press)
- Data Source
  KAKENHI-PROJECT-16791139
[Journal Article] Dolomite supplementation improves bone metabolism through modulation of calcium-regulating hormone secretion in ovariectomized rats.2005
- Author(s)
  Mizoguchi T et al.
- Journal Title
  
  J Bone Miner Metab (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390565
[Journal Article] Dolomite supplementation improves bone metabolism through modulation of calcium-regulating hormone secretion in ovariectomized rats.2005
- Author(s)
  Mizoguchi T, et al.
- Journal Title
  
  J Bone Miner Metab 23
  
  Pages: 140-146
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390641
[Journal Article] Dolomite supplementation improves bone metabolism through modulation of calcium-regulating hormone secretion in ovariectomized rats.2005
- Author(s)
  Mizoguchi T et al.
- Journal Title
  
  J Bone Miner Metab (in press)
- Data Source
  KAKENHI-PROJECT-15659445
[Journal Article] 海外文献紹介:ヒストン脱アセチル化酵素4(HDAC4)は、骨格形成における軟骨の肥大化をコントロールしている.2005
- Author(s)
  溝口利英
- Journal Title
  
  THE BONE 19・3
  
  Pages: 338-339
- Data Source
  KAKENHI-PROJECT-16791139
[Journal Article] RANKL/RANK系による骨吸収の制御2003
- Author(s)
  溝口利英他
- Journal Title
  
  治療学 37・12
  
  Pages: 18-23
- Data Source
  KAKENHI-PROJECT-16791139
[Presentation] チャネルキナーゼTRPM7の骨格形成における発現と軟骨形成制御2019
- Author(s)
  進正史・森志穂美・溝口利英・岡本富士雄・鍛治屋浩・荒井敦・宇田川信之・岡部幸司
- Organizer
  第３７回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03822
[Presentation] 破骨細胞に発現するSiglec-15の骨代謝カップリングにおける重要性2018
- Author(s)
  宇田川信之、上原俊介、小出雅則、荒井敦、溝口利英、中村美どり、小林泰浩、高橋直之、福田千恵、津田英資
- Organizer
  第3回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-16K11798
[Presentation] 骨髄間葉系幹細胞は低レベルにRunx2を発現している2018
- Author(s)
  溝口利英、楊孟雨、荒井敦、小林泰浩、宇田川信之、高橋直之
- Organizer
  第3回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-16K11798
[Presentation] Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15) plays important roles in the induction of both bone-resorbing activity of osteoclasts and osteoblast differentiation2018
- Author(s)
  Udagawa N, Koide M, Uehara S, Arai A, Mizoguchi T, Yamashita T, Nakamura M, Kobayashi Y, Takahashi N, Kumakura S, Fukuda C, Tsuda E
- Organizer
  The American Society for Bone and Mineral Research (ASBMR) 2018 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05508
[Presentation] 象牙芽細胞の枯渇は修復象牙質を誘導する2018
- Author(s)
  趙　麗娟、荒井　敦、堀部寛治、楊孟雨、細矢明宏、小林泰浩、宇田川信之、高橋直之、溝口利英
- Organizer
  第58回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11664
[Presentation] 破骨細胞に発現するSiglec-15の骨代謝カップリングにおける重要性2017
- Author(s)
  20.宇田川信之, 上原俊介, 小出雅則, 荒井敦, 溝口利英, 中村美どり,小林泰浩, 高橋直之, 福田千恵, 津田英資
- Organizer
  第3回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 先端歯学スクールシンポジウム：骨髄間葉系幹細胞による骨代謝制御機構の解析2017
- Author(s)
  溝口利英
- Organizer
  第59回歯科基礎医学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] Vdr in osteoblast-lineage cells primarily mediates a 1α,25(OH)2D3 derivative-induced increase in bone mass by suppressing bone resorption2017
- Author(s)
  Nakamichi, Y., Udagawa, N., Horibe, K., Mizoguchi, T., Yamamoto, Y., Nakamura, T., Hosoya, A., Kato, S., Suda, T., and Takahashi, N.
- Organizer
  20th Vitamin D Workshop, March, 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] Anti-Siglec-15 antibody inhibits bone-resorbing activity of osteoclasts and stimulates osteoblast differentiation.2017
- Author(s)
  Udagawa N, Uehara S, Koide M, Arai A, Mizoguchi T, Nakamura M, Kobayashi Y, Takahashi N, Fukuda C, Tsuda E
- Organizer
  The American Society for Bone and Mineral Research (ASBMR) 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05508
[Presentation] 骨代謝を司る骨髄間葉系幹細胞の同定と機能解析2017
- Author(s)
  溝口利英
- Organizer
  第419回東京歯科大学大学院セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] イブニング教育講演：骨髄間葉系幹細胞による骨代謝制御2017
- Author(s)
  溝口利英
- Organizer
  第35回日本骨代謝学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] アップデートシンポジウム：骨髄間葉系幹細胞の骨代謝制御機構2017
- Author(s)
  溝口利英
- Organizer
  第59回歯科基礎医学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 骨芽細胞系列のビタミンD受容体(VDR)は、ビタミンDによる骨量上昇効果とミネラル代謝に関与する2017
- Author(s)
  中道裕子, 堀部寛治, 溝口利英, 山本陽子, 中村貴, 細矢明宏, 加藤茂明, 須田立雄, 宇多川信之, 高橋直之
- Organizer
  第2回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 教育講演１：造血幹細胞ニッチ：最新の知見2017
- Author(s)
  溝口利英
- Organizer
  第2回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] VDR IN OSTEOBLAST-LINEAGE CELLS PRIMARILY MEDIATES A 1α,25(OH)2D3 DERIVATIVE-INDUCED INCREASE IN BONE MASS BY SUPPRESSING BONE RESORPTION2017
- Author(s)
  Nakamichi Y, Udagawa N, Horibe K, Mizoguchi T, Yamamoto Y, Nakamura T, Hosoya A, Kato S, Suda T, and Takahashi N
- Organizer
  The 20th Workshop on Vitamin D
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11664
[Presentation] 骨髄間葉系幹細胞の骨代謝における重要性2017
- Author(s)
  溝口利英
- Organizer
  第245回ゲノム医学研究センター学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] カテプシンＫ阻害剤投与は、オステオプロテゲリン欠損マウスにおいて、骨吸収抑制と共に骨形成促進作用を示す2017
- Author(s)
  中村美どり，中道裕子，溝口利英，小林泰浩，高橋直之，宇田川信之
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-15K11377
[Presentation] 髄間葉系幹細胞は低レベルにRunx2を発現している2017
- Author(s)
  溝口利英, 楊孟雨, 荒井敦, 小林泰浩, 宇田川信之, 高橋直之
- Organizer
  第3回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] ビタミンDの骨量増加の薬理作用は、破骨細胞ではなく骨芽細胞のVDRを介する2016
- Author(s)
  中道裕子、溝口利英、山本陽子、中村貴、細矢明宏、堀部寛治、原田卓、斎藤一史、加藤茂明、須田立雄、宇田川信之、高橋直之
- Organizer
  第34回日本骨代謝学会
- Place of Presentation
  大阪国際会議場　大阪
- Year and Date
  2016-07-22
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] 細胞系譜解析による生体内における骨髄間葉系幹細胞の同定と機能解明2016
- Author(s)
  溝口利英
- Organizer
  第37回日本炎症再生医学会
- Place of Presentation
  京都市勧業館みやこめっせ　(京都府・京都市)
- Year and Date
  2016-06-17
- Invited
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] カテプシンＫ阻害剤投与は、オステオプロテゲリン欠損マウスにおいて、骨吸収抑制と共に骨形成促進作用を示す2016
- Author(s)
  宇田川信之、中村美どり、中道裕子、溝口利英、小林泰浩、高橋直之
- Organizer
  第83回松本歯科大学学会
- Place of Presentation
  松本歯科大学　(長野県・塩尻市)
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] ビタミンDの骨量増加の薬理作用は、破骨細胞ではなく骨芽細胞のVDRを介する2016
- Author(s)
  中道裕子、溝口利英、山本陽子、中村貴、細矢明宏、堀部寛治、原田卓、斎藤一史、加藤茂明、須田立雄、宇田川信之、高橋直之
- Organizer
  第34回日本骨代謝学会学術集会
- Place of Presentation
  大阪国際会議場（大阪市）
- Year and Date
  2016-07-21
- Data Source
  KAKENHI-PROJECT-16K11664
[Presentation] カテプシンＫ阻害剤投与は、オステオプロテゲリン欠損マウスにおいて、骨吸収抑制と共に骨形成促進作用を示す2016
- Author(s)
  中村美どり, 中道裕子, 溝口利英, 小林泰浩, 高橋直之, 宇田川信之
- Organizer
  日本骨代謝学会学術集会 (第34回)
- Place of Presentation
  大阪国際会議場（大阪府）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-16H05508
[Presentation] カテプシンＫ阻害剤投与は、オステオプロテゲリン欠損マウスにおいて、骨吸収抑制と共に骨形成促進作用を示す2016
- Author(s)
  中村美どり、中道裕子、溝口利英、小林泰浩、高橋直之、宇田川信之
- Organizer
  第34回日本骨代謝学会
- Place of Presentation
  大阪国際会議場　(大阪府・大阪市)
- Year and Date
  2016-07-22
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] 破骨細胞と骨芽細胞の起源2016
- Author(s)
  溝口利英
- Organizer
  第34回日本骨代謝学会
- Place of Presentation
  大阪国際会議場　（大阪府・大阪市)
- Year and Date
  2016-07-22
- Invited
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] PTHアナボリック作用に対する骨髄間葉系幹細胞の寄与2016
- Author(s)
  楊孟雨、溝口利英、宇田川信之、松尾光一、小守壽文、森石武史、小林泰浩、高橋直之
- Organizer
  第34回日本骨代謝学会
- Place of Presentation
  大阪国際会議場　(大阪府・大阪市)
- Year and Date
  2016-07-22
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] 細胞系譜解析による生体内における骨髄間葉系幹細胞の解析2016
- Author(s)
  溝口利英
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌コンベンションセンター　(北海・札幌市)
- Year and Date
  2016-08-24
- Invited
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] 生体内における骨髄間葉系幹細胞の同定と制御機構の解析2016
- Author(s)
  溝口利英
- Organizer
  第2回Craniofacial and Stem Cell Biology Seminar 第153回 ECM Society
- Place of Presentation
  岡山大学歯学部　(岡山県・岡山市)
- Year and Date
  2016-10-14
- Invited
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] 発生過程における骨髄間葉系幹細胞の起源2015
- Author(s)
  溝口利英
- Organizer
  お茶の水がん学アカデミア第113回集会
- Place of Presentation
  順天堂大学医学部(東京都)
- Year and Date
  2015-04-15
- Invited
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] 生体内における骨髄間葉系幹細胞の同定2015
- Author(s)
  溝口利英
- Organizer
  第１回日本骨免疫学会
- Place of Presentation
  ホテルブリーズベイマリーナ(沖縄)
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] 発生過程における骨髄間葉系幹細胞の起源2015
- Author(s)
  溝口利英
- Organizer
  第9回骨・軟骨フロンティア
- Place of Presentation
  ベルサール八重洲(東京)
- Year and Date
  2015-11-07
- Invited
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] Developmental origin of bone marrow mesenchymal stem cells2015
- Author(s)
  溝口利英
- Organizer
  第12回Bone Biology Forum
- Place of Presentation
  クロスウェーブ幕張(千葉)
- Year and Date
  2015-08-22
- Invited
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] Analysis of the relationship between bone marrow environment and bone metabolism.2015
- Author(s)
  Toshihide Mizoguchi
- Organizer
  3rd Osteoclast Biology Meeting
- Place of Presentation
  ホテルマロウド(長野県)
- Year and Date
  2015-02-20
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] 発生過程における骨髄間葉系幹細胞の起源2015
- Author(s)
  溝口利英
- Organizer
  第14回松本ボーンフォーラム
- Place of Presentation
  信州大学医学部(長野)
- Year and Date
  2015-05-16
- Invited
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] 発生過程における骨髄間葉系幹細胞の起源2015
- Author(s)
  溝口利英
- Organizer
  第33回日本骨代謝学会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2015-07-24
- Invited
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] 発生過程における骨髄間葉系幹細胞の起源2014
- Author(s)
  溝口利英、宇田川信之、高橋直之
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡国際会議場(福岡県)
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] Osterix+ cells in developing bone marrow contain the origin of bone marrow stem and progenitor cells in adult marrow2014
- Author(s)
  Toshihide Mizoguchi, Nobuyuki Udagawa, Naoyuki Takahashi, Paul S. Frenette.
- Organizer
  第11回Bone Biology Forum
- Place of Presentation
  富士教育研修所(静岡県)
- Year and Date
  2014-08-22
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] Osterix+ cells in developing bone marrow contain the origin of bone marrow stem and progenitor cells in adult marrow.2014
- Author(s)
  Toshihide Mizoguchi
- Organizer
  Joint symposium of KSBMR and BMTRC in the annual fall meeting of KSBMR
- Place of Presentation
  カトリック大学(Seoul, Korea)
- Year and Date
  2014-11-15
- Invited
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] 発生過程におけるOsterix陽性細胞は骨髄間葉系幹細胞に寄与する2014
- Author(s)
  溝口利英
- Organizer
  第17回骨代謝研究会
- Place of Presentation
  慶応義塾大学医学部(東京都)
- Year and Date
  2014-11-29
- Invited
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] In vivoにおける破骨細胞前駆細胞の同定と分化機構の解析2010
- Author(s)
  溝口利英
- Organizer
  Osteoimmunology Forum(第7回)
- Place of Presentation
  東京大学(東京)
- Year and Date
  2010-02-06
- Data Source
  KAKENHI-PROJECT-20200019
[Presentation] Isolation and characterization of osteoclast precursors in vivo2010
- Author(s)
  Mizoguchi T
- Organizer
  Bone Research Seminar(第4回)
- Place of Presentation
  東京・東京コンファレンスセンター
- Year and Date
  2010-02-19
- Data Source
  KAKENHI-PROJECT-20200019
[Presentation] Isolation and characterization of osteoclast precursors in vivo2010
- Author(s)
  溝口利英
- Organizer
  Bone Research Seminar
- Place of Presentation
  東京コンファレンスセンター(東京)
- Year and Date
  2010-02-19
- Data Source
  KAKENHI-PROJECT-20200019
[Presentation] In vivoにおける破骨細胞前駆細胞の同定と分化機構の解析2010
- Author(s)
  溝口利英
- Organizer
  Osteoimmunology Forum(第7回)
- Place of Presentation
  東京大学(東京)
- Year and Date
  2010-02-06
- Data Source
  KAKENHI-PROJECT-22791804
[Presentation] In vivoにおける破骨細胞前駆細胞の同定と分化機構の解析2010
- Author(s)
  溝口利英
- Organizer
  Osteoimmunology Forum(第7回)
- Place of Presentation
  東京・東京大学
- Year and Date
  2010-02-06
- Data Source
  KAKENHI-PROJECT-20200019
[Presentation] Isolation and characterization of osteoclast precursors in vivo2010
- Author(s)
  溝口利英
- Organizer
  Bone Research Seminar
- Place of Presentation
  東京コンファレンスセンター(東京)
- Year and Date
  2010-02-19
- Data Source
  KAKENHI-PROJECT-22791804
[Presentation] Isolation and characterization of osteoclast precursors in vivo2010
- Author(s)
  Mizoguchi T
- Organizer
  2^<nd> International Bone and Mineral Society Davos Workshop
- Place of Presentation
  ダボス、スイス
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-20200019
[Presentation] Wntシグナルによる破骨細胞分化調節機構の解析2010
- Author(s)
  小林泰浩、溝口利英、上原俊介、高橋直之、宇田川信之
- Organizer
  第71回松本歯科大学学会例会
- Place of Presentation
  塩尻
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-21390551
[Presentation] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo2009
- Author(s)
  溝口利英
- Organizer
  硬組織研究セミナー(第5回)
- Place of Presentation
  東京・慶応義塾大学
- Year and Date
  2009-07-01
- Data Source
  KAKENHI-PROJECT-20200019
[Presentation] The influence of titanium-dioxide-doped phosphate-based glass on MC3T3-E12009
- Author(s)
  溝口利英
- Organizer
  87^<nd> General Session & Exhibition of the IADR
- Place of Presentation
  マイアミ・USA
- Year and Date
  2009-04-03
- Data Source
  KAKENHI-PROJECT-20791365
[Presentation] 生体内における破骨細胞前駆細胞の同定と性状解析2009
- Author(s)
  溝口利英
- Organizer
  骨発生・再生研究会(第12回)
- Place of Presentation
  東京・慶応義塾大学
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-20200019
[Presentation] The influence of titanium-dioxide-doped phosphate-based glass on MC3T3-E12009
- Author(s)
  Toshihie Mizoguchi
- Organizer
  87nd General Session & Exhibition of the IADR
- Place of Presentation
  マイアミ・USA
- Year and Date
  2009-04-03
- Data Source
  KAKENHI-PROJECT-20791365
[Presentation] 破骨細胞前駆細胞の同定と動態解析2009
- Author(s)
  溝口利英
- Organizer
  運動器科学研究会(第10回)
- Place of Presentation
  東京・東京ステーションコンファレンス
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-20200019
[Presentation] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo2009
- Author(s)
  溝口利英
- Organizer
  硬組織研究セミナー(第5回)
- Place of Presentation
  東京・慶応義塾大学
- Year and Date
  2009-07-01
- Data Source
  KAKENHI-PROJECT-20791365
[Presentation] Characterization of cell cycle-arrested quiescent osteoclast precursors2009
- Author(s)
  溝口利英
- Organizer
  第26回内藤カンファレンスオステオバイオロジー
- Place of Presentation
  兵庫・淡路夢舞台国際会議場
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-20200019
[Presentation] 「ミニシンポジウム」骨芽細胞/ストローマ細胞が支持する破骨細胞ニッチ2009
- Author(s)
  溝口利英
- Organizer
  日本骨代謝学会学術集会(第27回)
- Place of Presentation
  大阪・大阪国際会議場
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-20791365
[Presentation] The influence of titanium-dioxide-doped phosphate-based glass on MC3T3-E12009
- Author(s)
  Mizoguchi T
- Organizer
  87^<nd> General Session & Exhibition of the IADR
- Place of Presentation
  マイアミ・USA
- Year and Date
  2009-04-03
- Data Source
  KAKENHI-PROJECT-20200019
[Presentation] Characterization of cell cycle-arrested quiescent osteoclast precursors2009
- Author(s)
  溝口利英
- Organizer
  第26回内藤カンファレンスオステオバイオロジー
- Place of Presentation
  兵庫・淡路夢舞台国際会議場
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-20200019
[Presentation] Characterization of cell cycle-arrested quiescent osteoclast precursors2009
- Author(s)
  溝口利英
- Organizer
  第26回内藤カンファレンスオステオバイオロジー
- Place of Presentation
  兵庫・淡路夢舞台国際会議場
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-20791365
[Presentation] 破骨細胞前駆細胞の同定と動態解析2009
- Author(s)
  溝口利英
- Organizer
  運動器科学研究会(第10回)
- Place of Presentation
  東京・東京ステーションコンファレンス
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-20791365
[Presentation] 「ミニシンポジウム」骨芽細胞/ストローマ細胞が支持する破骨細胞ニッチ2009
- Author(s)
  溝口利英
- Organizer
  日本骨代謝学会学術集会(第27回)
- Place of Presentation
  大阪・大阪国際会議場
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-20200019
[Presentation] 生体内における破骨細胞前駆細胞の同定と性状解析2009
- Author(s)
  溝口利英
- Organizer
  骨発生・再生研究会(第12回)
- Place of Presentation
  東京・慶応義塾大学
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-20791365
[Presentation] An osteoclast niche is composed of 5-FU-insensitive osteoclast precursors in vivo.2007
- Author(s)
  Toshihide Mizoguchi, et. al.
- Organizer
  The 29th annual meeting of the American society for bone and mineral research
- Place of Presentation
  Hawaii convention center
- Year and Date
  2007-09-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390557
[Presentation] In vivoにおいて細胞周期の停止した破骨細胞前駆細胞(pOCP)は5-FU非感受性である2007
- Author(s)
  溝口利英、武藤昭紀、細矢明宏、中道裕子、山下照仁、小林泰浩、宇田川信之、伊藤充雄、高橋直之
- Organizer
  日本骨代謝学会
- Place of Presentation
  大阪市大阪国際会議場
- Year and Date
  2007-07-21
- Data Source
  KAKENHI-PROJECT-19592163
[Presentation] 骨芽細胞/ストローマ細胞が支持する破骨細胞ニッチ2007
- Author(s)
  溝口利英
- Organizer
  歯科基礎医学会(第49回)
- Place of Presentation
  北海道
- Year and Date
  2007-08-30
- Data Source
  KAKENHI-PROJECT-18791376
[Presentation] In vivoにおいて細胞周期の停止した破骨細胞前駆細胞(pOCP)は5-FU悲感受性である2007
- Author(s)
  溝口利英
- Organizer
  日本骨代謝学会(第25回)
- Place of Presentation
  大阪
- Year and Date
  2007-07-19
- Data Source
  KAKENHI-PROJECT-18791376
[Presentation] In vivoにおいて細胞周期の停止した破骨細胞前駆細胞(pOCP)は5-FU非感受性である2007
- Author(s)
  溝口利英, 他
- Organizer
  日本骨代謝学会
- Place of Presentation
  大阪市大阪国際会議場
- Year and Date
  2007-07-21
- Data Source
  KAKENHI-PROJECT-19592163
[Presentation] An Osteoclast Niche Is Composed of 5-FU-insensitive Osteoclast Precursors In Vivo2007
- Author(s)
  Toshihide Mizoguchi
- Organizer
  29th American Society for Bone and Mineral Research(ASBMR)Annual Meeting
- Place of Presentation
  ハワイ,USA
- Year and Date
  2007-09-19
- Data Source
  KAKENHI-PROJECT-18791376
[Presentation] An osteoclast niche is composed of 5-FU-insensitive osteoclast precursors in vivo2007
- Author(s)
  Toshihide Mizoguchi, et. al.
- Organizer
  第29回米国骨代謝学会
- Place of Presentation
  Hawaii Convention Center
- Year and Date
  2007-09-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390557
[Presentation] 破骨細胞のMAPキナーゼp38経路を制御する因子Alixの同定2007
- Author(s)
  山下照仁、溝口利英、小林泰浩、二宮禎、宇田川信之、高橋直之
- Organizer
  日本骨代謝学会
- Place of Presentation
  大阪市大阪国際会議場
- Year and Date
  2007-07-21
- Data Source
  KAKENHI-PROJECT-19592163

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mizoguchi toshihide 溝口 利英

Mizoguchi Toshihide 溝口 利英

MIZOGUCHI Toshihide 溝口 利英

溝口 俊英 ミゾグチ トシヒデ

Research Projects

Research Products

Co-Researchers

Identification of novel dental pulp stem cells and analysis of their regulatory mechanisms of differentiationPrincipal InvestigatorOngoing

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性ホルモンと機械的刺激による変形性顎関節症の病態発生機序の解明とその治療戦略Ongoing

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象牙芽細胞の機能と分化を制御するマルチシグナルを標的とする象牙質再生創薬基盤確立Ongoing

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破骨細胞が制御する骨髄老化機構の解明と造血機能の若返りへの応用Principal InvestigatorOngoing

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チャネルキナーゼTRPM7による骨格形成制御機構の解明Ongoing

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Mechanism of stemness regulation of mesenchymal stem cells on spheroid formationOngoing

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A study on bioactive ceramic biomaterialsOngoing

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Analysis of osteoclast precursor niche regulated by mesenchymal stem cells(Fostering Joint International Research)Principal Investigator

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Analysis of reparative dentin formation regulated by dental pulp stem cells using a fate mapping approachPrincipal Investigator

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mizoguchi toshihide 溝口利英

Mizoguchi Toshihide 溝口利英

MIZOGUCHI Toshihide 溝口利英

溝口俊英ミゾグチトシヒデ