Okano James Hirotaka 岡野ジェイムス洋尚

… Alternative Names

Researcher Number	90338020
Other IDs
Affiliation (Current)	2021: 東京慈恵会医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2012 – 2021: 東京慈恵会医科大学, 医学部, 教授 2007 – 2010: Keio University, 医学部, 准教授 2009: 医学部, 准教授 2004 – 2006: 慶應義塾大学, 医学部, 助教授 2002 – 2003: 慶應義塾大学, 医学部, 専任講師 2002 – 2003: 慶應義塾大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Biological Sciences / Neuroscience in general / Neurology / Neuroscience in general / Environmental physiology(including physical medicine and nutritional physiology) / Neurology / Basic Section 51030:Pathophysiologic neuroscience-related Except Principal Investigator Surgery related to the biological and sensory functions and related fields / Basic Section 52040:Radiological sciences-related / Otorhinolaryngology … More
Keywords	Principal Investigator RNA結合タンパク質 / Hu / 翻訳調節 / 神経細胞 / 神経変性疾患 / ユビキチンリガーゼ / タンパク質分解 / シナプス / 神経伝達物質 / 軸索輸送 … More Except Principal Investigator 耳科学 / 内耳再生 / 聴覚医学 / 橋渡し研究 / hiPS細胞 / トランスレーショナルリサーチ / 再生医療 / ヒトiPS細胞 / iPS創薬スクリーニング / マーモセット / 霊長類モデル / 分子・細胞神経科学 / RNA結合タンパク質 / 神経幹細胞 / 翻訳調節 / 神経分化 / Hu Hzf Musashi / p21Cip1 / Hu / Hzf / 翻訳調 / Musashi / p21Cipl / IP3受容体 / RNA結合タンパク / Schwann細胞 / 人工神経 / 神経移植 / 組織工学 / 再生医学 / 末梢神経 / ティッシュエンジニアリング / Schwann cell / artificial nerve / nerve graft / 精神疾患 / 統合失調症 / 家系 / ゲノム / iPSC / iPS細胞 / ゲノム解析 / iPS / schizophrenia / mood disorder / 拡張現実 / 内視鏡下耳科手術 / 顔面神経麻痺 / 霊長類研究 / 難聴医学 / 嗅神経分布 / トラクトグラフィー / 高磁場MRI機 / 拡散テンソルイメージング / 嗅覚 / DTI / 匂いの地図 / NIRS / fMRI / oxygen inspiration / 高次脳活動 / 酸素吸入 / 脳血液量増加持続時間 / 注視点計測 / 近赤外分光分析 / 医用画像読影 Less

家族性パーキンソン病PARK17由来iPS細胞を用いた根幹病態の解明と治療薬開発Principal InvestigatorOngoing
- Principal Investigator
  
  岡野ジェイムス洋尚
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Jikei University School of Medicine
NIRSを用いた高次脳活動時の脳血液量増加持続時間の解析Ongoing
- Principal Investigator
  
  関根紀夫
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Tokyo Metropolitan University
Development of novel therapeutics for the cochlear hearing impairments by using hiPSCs and common marmoset modelsOngoing
- Principal Investigator
  
  藤岡正人
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Keio University
Influence of high concentrated oxygen inhalation on cerebral blood flow during higher brain functioningOngoing
- Principal Investigator
  
  白川崇子
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Tokyo Metropolitan University
AR-navigated transcanal endoscopic inner ear sugery
- Principal Investigator
  
  OGAWA Kaoru
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Surgery related to the biological and sensory functions and related fields
- Research Institution
  Keio University
Establishment of RNA-based Biomarkers for ALSPrincipal Investigator
- Principal Investigator
  
  Okano Hirotaka James
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Jikei University School of Medicine
Visualizing the olfactory map with diffusion tensor imaging: Development of an objective olfactory test methodOngoing
- Principal Investigator
  
  鄭雅誠
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Surgery related to the biological and sensory functions and related fields
- Research Institution
  Jikei University School of Medicine
Pre-clinical proof of concept trials for auditory hair cell regeneration by using hiPSC technology and marmoset model
- Principal Investigator
  
  Fujioka Masato
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Keio University
Pathogenesis of schizophrenia using neural induction system from iPS Cell
- Principal Investigator
  
  MATSUSHITA Masayuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  University of the Ryukyus
Effects of high-energy particles on neural activityPrincipal Investigator
- Principal Investigator
  
  Okano Hirotaka James
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Jikei University School of Medicine
遅発性小脳失調モデル動物を用いた軸索変性機序の解明Principal Investigator
- Principal Investigator
  
  岡野ジェイムス洋尚
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Jikei University School of Medicine
遅発性小脳失調モデル動物を用いた軸索変性機序の解明Principal Investigator
- Principal Investigator
  
  岡野ジェイムス洋尚
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Jikei University School of Medicine
Analyses of regulatory mechanisms of TDP-43 level and risk factor of ALSPrincipal Investigator
- Principal Investigator
  
  OKANO Hirotaka James
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Jikei University School of Medicine
神経特異的ユビキチンリガーゼKspotによるシナプス制御Principal Investigator
- Principal Investigator
  
  岡野ジェイムス洋尚
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
中枢神経特異的ユビキチンリガーゼKspotによるシナプス制御Principal Investigator
- Principal Investigator
  
  岡野ジェイムス洋尚
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
Regulation of neuronal differentiation and plasticity at posttranscriptional level
- Principal Investigator
  
  OKANO Hideyuki
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
p27Kipl mRNA非翻訳領域SNPと翻訳促進活性・癌危険度との関連Principal Investigator
- Principal Investigator
  
  岡野ジェイムス洋尚
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
The Role of RNA Binding Protein Hu in Neuronal DifferentiationPrincipal Investigator
- Principal Investigator
  
  OKANO Hirotaka, James
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Keio University
The Role of RNA Binding Protein Hu in pathophysiology of the paraneoplastic neurologic disorders (PND's)Principal Investigator
- Principal Investigator
  
  OKANO Hirotaka james
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  KEIO UNIVERSITY
Experimental studies on peripheral nerve regeneration through the bio-nerve with 3D cultured Schwann cell
- Principal Investigator
  
  NAKAO Yasushi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  KEIO UNIVERSITY

[Book] The 3-Dimensional Atlas of the Marmoset Brain: Reconstructible in Stereotaxic Coordinates (Brain Science).2019
- Author(s)
  Iriki A, Okano HJ, Sasaki E, Okano H.
- Total Pages
  399
- Publisher
  Springer
- ISBN
  9784431566106
- Data Source
  KAKENHI-PROJECT-17K09766
[Book] 神経科学の最前線とリハビリテーション　脳の可塑性と運動2015
- Author(s)
  岡野ジェイムス洋尚
- Total Pages
  272
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PUBLICLY-26111723
[Book] 遺伝子医学 MOOK 26号「脳内環境―維持機構と破綻がもたらす疾患研究」2014
- Author(s)
  岡野ジェイムス洋尚
- Total Pages
  228
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PROJECT-24300122
[Book] 遺伝子医学 MOOK 26号「脳内環境―維持機構と破綻がもたらす疾患研究」2014
- Author(s)
  岡野ジェイムス洋尚
- Total Pages
  228
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PUBLICLY-26111723
[Book] Functions of neural RNA-binding proteins Musashi and Hu in stem cells and neuronal differentiation. RNA Binding Proteins in Development and Disease. (Edited by Robert B. Denman)2008
- Author(s)
  Kawahara, H., Yano, M., Imai, T., Akamatsu, W., Okano, HJ., Okano, H.
- Publisher
  Research Signpost, Kerala
- Data Source
  KAKENHI-PROJECT-17024051
[Book] Tissue Stem Cells ; Biology & Applications.2005
- Author(s)
  Okano H. et al.
- Total Pages
  383
- Publisher
  Taylor & Francis Group, New York
- Data Source
  KAKENHI-PROJECT-16500206
[Book] Tissue Stem Cells; Biblogy & Applicatibns.2005
- Author(s)
  Okano H. et al.
- Total Pages
  383
- Publisher
  Taylor & Francis Group, New York
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500206
[Journal Article] Neurite orientation dispersion and density imaging for evaluating the severity of neonatal hypoxic-ischemic encephalopathy in rats.2019
- Author(s)
  Ohki A, Saito S, Hata J, Okano HJ, Higuchi T, Fukuchi K.
- Journal Title
  
  Magn Reson Imaging.
  
  Volume: 62 Pages: 214-219
- DOI
  10.1016/j.mri.2019.07.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08172, KAKENHI-PROJECT-19K17254, KAKENHI-PROJECT-17K09766, KAKENHI-PROJECT-17K10421, KAKENHI-PROJECT-15K21774
[Journal Article] In vivo regeneration of interspecies chimeric kidneys using a nephron progenitor cell replacement system.2019
- Author(s)
  Fujimoto Toshinari、Yamanaka Shuichiro、Tajiri Susumu、Takamura Tsuyoshi、Saito Yatsumu、Matsumoto Kei、Takase Kentaro、Fukunaga Shohei、Okano Hirotaka James、Yokoo Takashi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Pages: 6965-6965
- DOI
  10.1038/s41598-019-43482-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17756, KAKENHI-PROJECT-16K09630, KAKENHI-PROJECT-17K09766, KAKENHI-PROJECT-17K16102
[Journal Article] Anatomical and Surgical Evaluation of the Common Marmoset as an Animal Model in Hearing Research2019
- Author(s)
  Kurihara S, Fujioka M, Hata J, Yoshida T, Hirabayashi M, Yamamoto Y, Ogawa K, Kojima H, Okano HJ.
- Journal Title
  
  Frontiers in Neuroanatomy
  
  Volume: 13 Pages: 1-10
- DOI
  10.3389/fnana.2019.00060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09766, KAKENHI-PROJECT-17K10421, KAKENHI-PROJECT-19K21357
[Journal Article] Elavl3 regulates neuronal polarity through the alternative splicing of an embryo-specific exon in AnkyrinG2018
- Author(s)
  Ogawa Y, Yamaguchi J, Yano M, Uchiyama Y, Okano HJ
- Journal Title
  
  Neuroscience Research
  
  Volume: - Pages: 13-20
- DOI
  10.1016/j.neures.2018.03.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16J11920, KAKENHI-PROJECT-17K09766, KAKENHI-PUBLICLY-17H05598, KAKENHI-PROJECT-16K07247
[Journal Article] A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset (Callithrix jacchus).2018
- Author(s)
  Kurihara S, Fujioka M, Yoshida T, Koizumi M, Ogawa K, Kojima H, Okano HJ.
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 132 Pages: 132-132
- DOI
  10.3791/56574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09766
[Journal Article] Elavl3 is essential for the maintenance of Purkinje neuron axons.2018
- Author(s)
  Ogawa Yuki、Kakumoto Kyoko、Yoshida Tetsu、Kuwako Ken-ichiro、Miyazaki Taisuke、Yamaguchi Junji、Konno Ayumu、Hata Junichi、Uchiyama Yasuo、Hirai Hirokazu、Watanabe Masahiko、Darnell Robert B.、Okano Hideyuki、Okano Hirotaka James
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Pages: 2722-2722
- DOI
  10.1038/s41598-018-21130-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08485, KAKENHI-PROJECT-17K09766, KAKENHI-PROJECT-16J11920, KAKENHI-PROJECT-15K06807, KAKENHI-PROJECT-16K14581, KAKENHI-PROJECT-16K15477, KAKENHI-PROJECT-15K18330
[Journal Article] Regenerative potential of induced pluripotent stem cells derived from patients undergoing haemodialysis in kidney regeneration.2018
- Author(s)
  Tajiri Susumu、Yamanaka Shuichiro、Fujimoto Toshinari、Matsumoto Kei、Taguchi Atsuhiro、Nishinakamura Ryuichi、Okano Hirotaka James、Yokoo Takashi
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Pages: 1-12
- DOI
  10.1038/s41598-018-33256-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09630, KAKENHI-PROJECT-17K09766, KAKENHI-PROJECT-17K16102, KAKENHI-PROJECT-16H03175, KAKENHI-PROJECT-19K21307
[Journal Article] Loss of DDHD2, whose mutation causes spastic paraplegia, promotes reactive oxygen species generation and apoptosis.2018
- Author(s)
  Maruyama Tomohiro、Baba Takashi、Maemoto Yuki、Hara-Miyauchi Chikako、Hasegawa-Ogawa Minami、Okano Hirotaka James、Enda Yuki、Matsumoto Kei、Arimitsu Nagisa、Nakao Kazuki、Hamamoto Hiroshi、Sekimizu Kazuhisa、Ohto-Nakanishi Takayo、Nakanishi Hiroki、Tokuyama Takeshi、Yanagi Shigeru、Tagaya Mitsuo、Tani Katsuko
- Journal Title
  
  Cell Death Dis.
  
  Volume: 9 Pages: 797-797
- DOI
  10.1038/s41419-018-0815-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07194, KAKENHI-PROJECT-17K09766, KAKENHI-PROJECT-17K10852, KAKENHI-PROJECT-18H02439
[Journal Article] Generation of interspecies limited chimeric nephrons using a conditional nephron progenitor cell replacement system2017
- Author(s)
  Yamanaka S, Tajiri S, Fujimoto T, Matsumoto K, Fukunaga S, Kim BS, Okano HJ, Yokoo T.
- Journal Title
  
  Nature Communications
  
  Volume: 8 Pages: 1719-1719
- DOI
  10.1038/s41467-017-01922-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09630, KAKENHI-PROJECT-17K09766, KAKENHI-PROJECT-17K16102
[Journal Article] Overlapping expression of anion exchangers in the cochlea of a non-human primate suggests functional compensation.2016
- Author(s)
  Hosoya M, Fujioka M, Kobayashi R, Okano H, Ogawa K.
- Journal Title
  
  Neuroscience Research
  
  Volume: S0168-0102(16) Pages: 300006-300006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04991
[Journal Article] 90.Hasegawa M, Hara-Miyauchi C, Ohta H, Sakimura K, Okano H, Okano HJ. (2016) Analysis of RNA metabolism in peripheral WBCs of TDP-43 KI mice identifies novel biomarkers of ALS.2016
- Author(s)
  Hasegawa, M.;Hara-Miyauchi, C.;Ohta, H.;Sakimura, K.;Okano, H.;Okano, H. J.
- Journal Title
  
  Neurosci Res.
  
  Volume: － Pages: 12-22
- DOI
  10.1016/j.neures.2015.11.009
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PUBLICLY-26111723, KAKENHI-PROJECT-26640007, KAKENHI-PLANNED-26117007
[Journal Article] Distinct Expression Patterns Of Causative Genes Responsible For Hereditary Progressive Hearing Loss In Non-Human Primate Cochlea.2016
- Author(s)
  Hosoya M, Fujioka M, Ogawa K, Okano H
- Journal Title
  
  Scientific Reports
  
  Volume: 26;6 Pages: 22250-22250
- DOI
  10.1038/srep22250
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15624, KAKENHI-PROJECT-15H04991, KAKENHI-PROJECT-24592560
[Journal Article] Sustained Effect of Hyaluronic Acid in Subcutaneous Administration to the Cochlear Spiral Ganglion.2016
- Author(s)
  Inagaki Y, Fujioka M, Kanzaki S, Watanabe K, Oishi N, Itakura G, Yasuda A, Shibata S, Nakamura M, Okano HJ, Okano H, Ogawa K.
- Journal Title
  
  PLoS One.
  
  Volume: 11
- DOI
  10.1371/journal.pone.0153957
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10762, KAKENHI-PROJECT-15K15624, KAKENHI-PROJECT-15H04991, KAKENHI-PROJECT-26462714
[Journal Article] Alternative Role of HuD Splicing Variants in Neuronal Differentiation.2015
- Author(s)
  Hayashi S, Yano M, Igarashi M, Okano HJ, Okano H.
- Journal Title
  
  J Neurosci Res.
  
  Volume: 93 Pages: 311-23
- DOI
  10.1002/jnr.23496
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300122, KAKENHI-PUBLICLY-26111723, KAKENHI-PLANNED-26117007
[Journal Article] Frontotemporal Dementia-associated N279K Tau Mutant Disrupts Subcellular Vesicle Trafficking and Induces Cellular Stress in iPSC-derived Neural Stem Cells.2015
- Author(s)
  Wren MC, Zhao J, Liu C-C, Murray ME, Atagi Y, Davis MD, Fu Y, Okano HJ, Ogaki K, Strongosky AJ, Tacik P, Rademakers R, Ross OA, Dickson DW, Wszolek ZK, Kanekiyo T, Bu G. 
- Journal Title
  
  Mol Neurodegener.
  
  Volume: 10 Pages: 46-46
- DOI
  10.1186/s13024-015-0042-7
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26111723
[Journal Article] Proposing a new RNA quadruplex structure: j-motif, with possible links to neural development.2014
- Author(s)
  Nakamura S, Igarashi M, Kinoshita M, Okano HJ, Okano H.
- Journal Title
  
  J Biochem.
  
  Volume: 未定 Pages: 385-392
- DOI
  10.1093/jb/mvu013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-24111543, KAKENHI-PROJECT-24300122
[Journal Article] Fetal sulcation and gyrification in common marmosets (Callithrix Jacchus) obtained by ex vivo magnetic resonance imaging.2014
- Author(s)
  Sawada K, Hikishima K, Murayama AY, Okano HJ, Sasaki E, Okano H.
- Journal Title
  
  Neuroscience
  
  Volume: 257 Pages: 158-174
- DOI
  10.1016/j.neuroscience.2013.10.067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300122
[Journal Article] Cadherin-7 Regulates Mossy Fiber Connectivity in the Cerebellum.2014
- Author(s)
  Kuwako K, Nishimoto Y, Kawase S, Okano HJ, Okano H.
- Journal Title
  
  Cell Reports
  
  Volume: 9 Pages: 311-23
- DOI
  10.1016/j.celrep.2014.08.063
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300122, KAKENHI-PROJECT-25430073, KAKENHI-PUBLICLY-26111723, KAKENHI-PLANNED-26117007
[Journal Article] The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis.2013
- Author(s)
  Nishimoto, Y., Nakagawa, S., Hirose, T., Okano, H. J., Takao, M., Shibata, S., Suyama, S., Kuwako, K., Imai, T., Murayama, S., Suzuki, N., and Okano, H
- Journal Title
  
  Molecular Brain
  
  Volume: 6 Pages: 31-31
- DOI
  10.1186/1756-6606-6-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21228003, KAKENHI-PUBLICLY-24111543, KAKENHI-PROJECT-24300122, KAKENHI-PROJECT-24500447, KAKENHI-PROJECT-24601016, KAKENHI-PROJECT-25430073
[Journal Article] Kspot, a novel ubiquitin ligase, regulates synaptic activity.2010
- Author(s)
  Tada H., Okano HJ., Takagi H., Shibata S., Matsumoto M., Yao I., Saiga T., Nakayama KI., Kashima H., Takahashi T, Setou M, Okano H.
- Journal Title
  
  J.Biol.Chem. 285(6)
  
  Pages: 3840-3849
- NAID
  130005449632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Fbxo45, a novel ubiquitin ligase, regulates synaptic activity.2010
- Author(s)
  Tada H, Okano HJ, Takagi H, Shibata S, Yao I, Matsumoto M, Saiga T, Nakayama KI, Kashima H, Takahashi T, Setou M, Okano H.
- Journal Title
  
  J Biol Chem. 285
  
  Pages: 3840-3849
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025029
[Journal Article] Stromal cell-secreted factors promote the survival of ES cell-derived early neural stem/progenitor cells via the activation of MAPK and PI3K-Akt pathways.2010
- Author(s)
  Ishii S., Okada Y., Kadoya T., Matsuzaki Y., Shimazaki T., Okano H.
- Journal Title
  
  J.Neurosci.Res. 88(4)
  
  Pages: 722-773
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development.2009
- Author(s)
  Saiga T, Fukuda T, Matsumoto M, Tada H, Okano HJ, Okano H, Nakayama KI.
- Journal Title
  
  Mol Cell Biol. 29
  
  Pages: 3529-3543
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025029
[Journal Article] Precursor maintenance and GABAergic neuronal differentiation mediated by the PDK1-Akt pathway in mouse telencephalon.2009
- Author(s)
  Oishi K., Watatani K., Yoshimatsu T., Masuyama N., Nakajima K., Okano H., Guillemot F., Alessi DR., Gotoh Y.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 106(31)
  
  Pages: 13064-13069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Cell types to order : Temporal specification of CNS stem cells.2009
- Author(s)
  Okano H., Temple S.
- Journal Title
  
  Current Opinion in Neurobiology 19
  
  Pages: 112-119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Musashi1 as a marker of reactive astrocytes after transient focal brain ischemia.2009
- Author(s)
  Oki K, Kaneko N, Kanki H Sa wamoto K, Okano H.
- Journal Title
  
  Neurosci. Res. 66(4)
  
  Pages: 390-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Musashi-1, an RNA-binding protein, is indispensable for survival of photoreceptors.2009
- Author(s)
  Susaki K, Kaneko J, Yamano Y, Nakamura K, In ami W, Yoshikawa T, Ozawa Y, Shibata S, Matsuzaki O, Okano H, Chiba C
- Journal Title
  
  Experimental eye research 88
  
  Pages: 47-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development.2009
- Author(s)
  Saiga T., Fukuda T., Matsumoto M., Tada H., Okano HJ., Okano H., Nakayama KI.
- Journal Title
  
  Mol.Cell Biol. 29(13)
  
  Pages: 3529-3543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Cyclic alopecia caused by the disruption of Sox21- mediated hair shaft cuticle differentiation.2009
- Author(s)
  Kiso M., Tanaka S., Saba R., Matsuda S., Shimizu A., Ohyama M., James-Okano H., Shiroishi T., Okano H., Saga Y.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 106(23)
  
  Pages: 9292-9297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] In vivo imaging in humanized mice2008
- Author(s)
  Masuda H., Okano HJ., Maruya ma T., Yoshimura Y., Okano H., Matsuzaki Y
- Journal Title
  
  Curr Top Microbiol Immunol 324
  
  Pages: 179-196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Hzf regulates adipogenesis through translational control of C/EBPa2008
- Author(s)
  Kawagishi H., Wakoh T., Uno H Maruyama M., Moriya A., Morikawa S., Okano H., Sherr C J., Takagi M., Sugimoto M.
- Journal Title
  
  EMBO J 27
  
  Pages: 1481-1490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Re quirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development.2008
- Author(s)
  Naka H, Nakamura S, Shimazaki T, Okano H
- Journal Title
  
  Nature neuroscience 11
  
  Pages: 1014-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article]2008
- Author(s)
  Kawahara H, Yano M, Imai T, Akamatsu W, Okano HJ, Okano H, Kawahara H, Yano M, Imai T, Akamatsu W, Okano HJ, Okano H
- Journal Title
  
  Kerala, India
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Spatio-temporal recapitulation of central nervous system development by ES cell-derived neural stem/progenitor cells2008
- Author(s)
  Okada Y., Matsumoto A., Shimazaki T., Enoki R., Koizumi A., Ishii S., Itoyama Y., Sobue G., Okano H.
- Journal Title
  
  Stem Cells 26
  
  Pages: 3086-3098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Stage/Cell cycle phase specific nestin gene expression coordinated with the morphological alteration of embryonic cortical neural progenitor cells2008
- Author(s)
  Sunabori T., Tokunaga A., Nagai T., Sawamoto K., Okabe M., Miyawaki A., Matsuzaki Y., Miyata T., Okano H
- Journal Title
  
  J. Cell Sci 121
  
  Pages: 1204-1212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Hzf regulates adipogenesis through translational control of C/EBPalpha.2008
- Author(s)
  Kawagishi H, Wakoh T, Uno H, Maruyama M, Mo riya A, Morikawa S, Okano H, Sherr CJ, Takagi M, Sugimoto M
- Journal Title
  
  The EMBO journal 27
  
  Pages: 1481-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] e ural RNA-binding protein Musashi1 Inhibits Translation Initiation by Competing with eIF4G for PABP.2008
- Author(s)
  Kawahara H, Imai T, Imataka H, Okano H.
- Journal Title
  
  J. Cell Biol. 181
  
  Pages: 639-653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Requirement for COUP-TFI and II in the temporal specification of neura I stem cells in central nervous system development2008
- Author(s)
  Naka H., Nakamura S., Shimazaki T., Okano H.
- Journal Title
  
  Nature Neurosci 11(9)
  
  Pages: 1014-1023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Impaired Motor Functions in Mice Lacking the RNA-binding Protein Hzf.2007
- Author(s)
  Iijima T, Ogura H, Takatsuki K, Shigenori Ka wahara S, Wakabayashi K, Nakayama D, Fujioka M, Kimura Y, Bernstein A, Okano HJ, Kirino Y, Okano H.
- Journal Title
  
  Neurosci Res 58
  
  Pages: 183-189
- NAID
  10024415208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Musashi-1 expression in postnatal mouse olfactory epithelium.2007
- Author(s)
  Watanabe K, Kondo K, Takeuchi N, Okano H, Yam asoba T
- Journal Title
  
  Neuroreort 18
  
  Pages: 641-644
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Coordinated Expression of HuD and GAP-43 in Hippocampal Dentate Granule Cells During Developmental and Adult Plasticity.2007
- Author(s)
  Bolognani F, Tanner DC, Nixon S, Okano HJ, Okano H, Perrone-Bizzozero NI.
- Journal Title
  
  eurochem Res. 32
  
  Pages: 2142-2151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Expression of neural RNA binding protein, Musashi1 in pediatric brain tumors.2007
- Author(s)
  Nakano A, Kanemura Y, Mori K, Kodama E, Ya mamoto A, Sakamoto H, Nakamura Y, Okano H, Yamasaki M, Arita N.
- Journal Title
  
  Pediatric Neurosurgery 43
  
  Pages: 279-283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells.2006
- Author(s)
  Sakaguchi M, Shingo T, S himazaki T, Okano HJ, Shiwa M, Ishibashi S, Oguro H, Ninomiya M, Kadoya T, Horie H, Shibuya A, Mizusawa H, Poirier F, Nakauchi H, Sawamoto K, Okano H.
- Journal Title
  
  Proc Natl Acad Sci USA. 103(18)
  
  Pages: 7112-7117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Musashi1 antigen expression in human fetal germinal matrix development.2006
- Author(s)
  Chan C, Moore BE, Cotman CW, Okano H, Tavares R, Hovanesian V, Pinar H, Johanson CE, Svendsen CN, Stopa EG
- Journal Title
  
  Exp Neurol. 201
  
  Pages: 515-518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] RNA-binding protein HuD regulates neuronal cell identity and maturation2005
- Author(s)
  Akamatsu W, Fujihara H, Mitsuhashi T, Yano M, Shibata S, Hayakawa Y, Okano HJ, Sakakibara S, Takano H, Takano T, Takahashi T, Noda T, Okano H.
- Journal Title
  
  Proc Natl Acad Sci USA. 102
  
  Pages: 4625-4630
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500206
[Journal Article] A novel marker for Purkinje cells, KIAA0864 protein. An analysis based on a monoclonal antibody HFB-16 in developing human cerebellum.2005
- Author(s)
  Nakamura Y, Yamamoto M, Oda E, Kanemura Y, Kodama E, Yamamoto A, Yamamoto H, Miyado K, Okano HJ, Fukagawa R, Higaki K, Yamasaki M, Okano H
- Journal Title
  
  J Histochem Cytochem. 53
  
  Pages: 423-430
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500206
[Journal Article] Nedd9 protein, a Cas-L homologue, is upregulated after transient global ischemia in Rats.2005
- Author(s)
  Sasaki T, Iwata S, Okano HJ, Urasaki Y, Hamada J, Tanaka H, Dang NH, Okano H, Morimoto C.
- Journal Title
  
  Stroke. 36
  
  Pages: 2457-2462
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500206
[Journal Article] Involvement of Hu and hnRNP K in neuronal differentiation through p21 mRNA post-transcriptional regulation2005
- Author(s)
  Yano M, Okano HJ, Okano H.
- Journal Title
  
  J Biol Chem 280
  
  Pages: 12690-12699
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500206
[Journal Article] Hzf Protein Regulates Dendritic Localization and BDNF-induced Translation of Type1 inositol 1,4,5-Trisphosphate Receptor mRNA2005
- Author(s)
  Iijima T, Imai T, Kimura Y, Bernstein A, Okano HJ, Yuzaki M, Okano H.
- Journal Title
  
  Proc Natl Acad Sci USA. 102
  
  Pages: 17190-17195
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500206
[Journal Article] Function of RNA-binding protein Musashi-1 in stem cells.2005
- Author(s)
  Okano H, Kawahara H, Toriya M, Nakao K, Shibata S, Imai T
- Journal Title
  
  Experimental cell research 306
  
  Pages: 349-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Involvement of Hu and heterogeneous nuclear ribonucleoprotein K in neuronal differentiation through p21 mRNA post-transcriptional regulation.2005
- Author(s)
  Yano M, Okano HJ, Oka no H
- Journal Title
  
  The Journal of biological chemistry 280
  
  Pages: 12690-12699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] In vivo imaging of engrafted neural stem cells : its application in evaluating the optimal timing of transplantation for spinal cord injury.2005
- Author(s)
  Okada S, Ishii K, Yamane J, Iwanami A, Ikegami T, Kato H, Iwamoto Y, Nakamura M, Miyoshi H, Okano HJ, Contag CH, Toyama Y, Okano H.
- Journal Title
  
  FASEB J. 19
  
  Pages: 1839-1841
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500206
[Journal Article] The RNA-binding protein HuD regulates neuronal cell identity and maturation.2005
- Author(s)
  Akamatsu W, Fujihara H, Mitsuhashi T, Yano M, Shibata S, Hayakawa Y, Okano HJ, Sakakibara S, Takano H, Takano T, Takahashi T, Noda T, Okano H
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America 102
  
  Pages: 4625-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Hzf protein regulates dendritic localization and BDNF-induced translation of type 1 inositol 1, 4, 5-trisphosphate receptor mRNA.2005
- Author(s)
  Iijima T, Imai T, Kimura Y, Bernstein A, Okano HJ, Yuzaki M, Okano H
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America 102
  
  Pages: 17190-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Patent] 筋萎縮性側索硬化症および／または前頭側頭葉変性症モデルマウス2013
- Inventor(s)
  岡野栄之　岡野ジェイムス洋尚　宮内央子
- Industrial Property Rights Holder
  岡野栄之　岡野ジェイムス洋尚　宮内央子
- Industrial Property Rights Type
  特許
- Filing Date
  2013-05-30
- Data Source
  KAKENHI-PROJECT-24300122
[Patent] 神経幹細胞の増殖抑制剤2010
- Inventor(s)
  岡野栄之、坂口昌徳、澤本和延、平林淳
- Industrial Property Rights Holder
  学校法人慶應義塾,(独)産業技術総合研究所
- Acquisition Date
  2010-02-16
- Data Source
  KAKENHI-PROJECT-17024051
[Patent] 神経幹細胞の増殖抑制剤2010
- Inventor(s)
  岡野栄之, 他
- Industrial Property Rights Holder
  学校法人慶應義塾、独立行政法人産業技術総合研究所
- Acquisition Date
  2010-02-16
- Data Source
  KAKENHI-PROJECT-17024051
[Patent] AGENT FOR TREATMENT OF NEURAL INJURY ADN METHOD OF THE SAME2008
- Inventor(s)
  (慶應)岡野栄之、中村雅也、辻収彦(共願先), 山中伸弥、三浦恭子
- Industrial Property Rights Holder
  学校法人慶應義塾、国立大学法人京都大学
- Filing Date
  2008-03-07
- Overseas
- Data Source
  KAKENHI-PROJECT-17024051
[Patent] METHOD FOR TREATING THENEURAL INJURY2008
- Inventor(s)
  (慶應)岡野栄之、中村雅也、辻収彦(共願先), 山中伸弥、三浦恭子
- Industrial Property Rights Holder
  学校法人慶應義塾、国立大学法人京都大学
- Filing Date
  2008-02-15
- Overseas
- Data Source
  KAKENHI-PROJECT-17024051
[Patent] 神経損傷治療剤及び神経損傷治療方法2008
- Inventor(s)
  岡野栄之、中村雅也、辻収彦、山中伸弥、三浦恭子
- Industrial Property Rights Holder
  学校法人慶応義塾大学、国立大学法人京都大学
- Filing Date
  2008-06-30
- Overseas
- Data Source
  KAKENHI-PROJECT-17024051
[Patent] 神経損傷治療剤及び神経損傷治療方法2008
- Inventor(s)
  岡野栄之, 他
- Industrial Property Rights Holder
  学校法人慶應義塾、国立大学法人京都大学
- Industrial Property Number
  2008-005844
- Filing Date
  2008-03-07
- Data Source
  KAKENHI-PROJECT-17024051
[Patent] 脊髄損傷治療藥剤2008
- Inventor(s)
  岡野栄之, 他
- Industrial Property Rights Holder
  学校法人慶應義塾、国立大学法人大阪大学、クリングルファーマ株式会社
- Filing Date
  2008-02-08
- Data Source
  KAKENHI-PROJECT-17024051
[Patent] 神経損傷治療剤及び神経損傷治療方法2008
- Inventor(s)
  (慶應)岡野栄之、中村雅也、辻収彦(共願先), 山中伸弥、三浦恭子
- Industrial Property Rights Holder
  学校法人慶應義塾、国立大学法人京都大学
- Industrial Property Number
  2008-058447
- Filing Date
  2008-03-07
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Pathophysiological consequences of Retromer dysfunction in Neurological Disorder2019
- Author(s)
  Hirotaka James Okano
- Organizer
  The 5th International Forum for Lysosomal Storage Diseases
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09766
[Presentation] Pathophysiological studies of familial Parkinson’s Disease PARK17 using iPSC technology2019
- Author(s)
  Hirotaka James Okano
- Organizer
  BRIMS International Neuroscience Symposium 2019 [Neurodegenerative Diseases & Brain Ageing]
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09766
[Presentation] Visualizing the Olfactory Nerve with Ultra-high Field MRI Tractography2018
- Author(s)
  Masayoshi Tei, Sho Kurihara, Eri Mori, Junichi Hata, Hirotaka James Okano, Nobuyoshi Otori, Hiromi Kojima
- Organizer
  27th Congress of the European Rhinologic Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19735
[Presentation] Effects of high-energy particles on neural activity in primary cultured cortical neurons2017
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第7回国際放射線神経生物学会大会
- Place of Presentation
  越後湯沢温泉ホテル双葉、新潟
- Year and Date
  2017-02-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15044
[Presentation] ALS/ FTLD model of mutant TDP-43 knock-in mice2015
- Author(s)
  Hirotaka James Okano, Chikako Hara-Miyauchi, Junko Fujigasaki, Shigemi Itohara, Hideyuki Okano
- Organizer
  10th Brain Research Conference “RNA Metabolism in Neurological Disease”.
- Place of Presentation
  The Westin Chicago River North, Chicago, USA
- Year and Date
  2015-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26111723
[Presentation] MYO15A新規遺伝子変異症例からの疾患特異的iPS細胞の樹立と解析2015
- Author(s)
  藤岡正人、細谷　誠・松永　達雄・小川　郁・岡野　栄之
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15H04991
[Presentation] Analysis of axonal degeneration in HuC KO mice2015
- Author(s)
  Yuki Ogawa, Robert Darnell, Hideyuki Okano, Hirotaka James Okano
- Organizer
  10th Brain Research Conference “RNA Metabolism in Neurological Disease”.
- Place of Presentation
  The Westin Chicago River North, Chicago, USA
- Year and Date
  2015-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26111723
[Presentation] PENDRED症候群疾患特異的iPS細胞由来内耳細胞を用いた薬剤スクリーニング2015
- Author(s)
  細谷　誠、藤岡　正人、岡本　理志、曽根　岳史、松永　達雄、赤松　和土、小川　郁、岡野　栄之
- Organizer
  第36回日本炎症・再生医学会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京都港区）
- Year and Date
  2015-07-21
- Data Source
  KAKENHI-PROJECT-15H04991
[Presentation] ヒトES/iPS細胞をソースとした高純度内耳有毛細胞誘導系と人工蝸牛感覚上皮シート作成のこころみ2015
- Author(s)
  藤岡正人、細谷　誠、小川　郁、岡野　栄之
- Organizer
  第36回日本炎症・再生医学会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京都港区）
- Year and Date
  2015-07-21
- Data Source
  KAKENHI-PROJECT-15H04991
[Presentation] Analysis of axonal degenerative mechanisms in HuC KO mice2015
- Author(s)
  Yuki Ogawa, Kyoko Kakumoto, Junji Yamaguchi, Tetsu Yoshida, Robert Darnell, Yasuo Uchiyama, Hideyuki Okano, Hirotaka James Okano
- Organizer
  第38回日本神経科学会大会
- Place of Presentation
  神戸コンベンションセンター（神戸）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PUBLICLY-26111723
[Presentation] Function of Neuronal Elav-like (Hu) Proteins in Embryonic and Adult Brain2013
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第４回新潟大学脳研究所共同研究拠点国際シンポジウム
- Place of Presentation
  新潟大学脳研究所統合脳機能研究センター（新潟）
- Invited
- Data Source
  KAKENHI-PROJECT-24300122
[Presentation] RNA-binding protein HuC is required for maintenance of the axon in Purkinje cells2013
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第３６回日本神経科学大会
- Place of Presentation
  京都国際会議場（京都）
- Data Source
  KAKENHI-PROJECT-24300122
[Presentation] RNA-binding protein HuC is required for maintenance of the axon in Purkinje cells2013
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第３６回日本神経科学大会
- Place of Presentation
  京都国際会議場（京都）
- Data Source
  KAKENHI-PUBLICLY-24111543
[Presentation] Function of Neuronal Elav-like (Hu) Proteins in Embryonic and Adult Brain2013
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第４回新潟大学脳研究所共同研究拠点国際シンポジウム
- Place of Presentation
  新潟大学脳研究所統合脳機能研究センター（新潟）
- Invited
- Data Source
  KAKENHI-PUBLICLY-24111543
[Presentation] HuC is required for maintenance of the axon in cerebellar Purkinje cells2012
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第３５回日本神経科学大会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2012-09-18
- Data Source
  KAKENHI-PUBLICLY-24111543
[Presentation] HuC is required for maintenance of the axon in cerebellar Purkinje cells2012
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-24300122
[Presentation] Fbxo45, a novel ubiquitin ligase, regulates synaptic activity2010
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  BMB2010
- Place of Presentation
  神戸コンベンションセンター、神戸市
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PUBLICLY-21025029
[Presentation] Genetically Modified Non-Human Primate Model of Human Neurodegenerative Diseases2010
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  International Brain Research Organization School Symposium 2010
- Place of Presentation
  Monash University Sunway campus, Malaysia
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PUBLICLY-21025029
[Presentation] 新規ユビキチンリガーゼFbxo45によるシナプス制御2010
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  Neuro2010
- Place of Presentation
  神戸コンベンションセンター、神戸市
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PUBLICLY-21025029
[Presentation] Roles of RNA Binding Protein Hu in Developing and Mature Neurons.2009
- Author(s)
  Hirotaka James Okano
- Organizer
  36th Intemational Congress Of Physiological Sciences (IUPS2009)
- Place of Presentation
  京都国際会議場
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Roles of RN A Binding Protein Hu in Developing and Mature Neurons.2009
- Author(s)
  Okano HJ.
- Organizer
  36th International Congress Of Physiological Sciences (IUPS2009)
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Post-transcriptional regulation of proliferation/differentiation switching in neural stem cells2008
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  34th Annual Meeting of Korean Cancer Association
- Place of Presentation
  Seoul, Korea
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19044038
[Presentation] Strategies for the regeneration of damaged CNS2008
- Author(s)
  Okano H.
- Organizer
  The 17th Biennial Meeting of the International Society for Developmental Neuroscience
- Place of Presentation
  Asilomar, CA, U.S.A.
- Year and Date
  2008-06-03
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Neural differentiation and cell therapy using pluripotent stem cells2008
- Author(s)
  Okano H.
- Organizer
  2nd Symposium on Brain and Mind Research in the Asia / Pacific (BMAP)
- Place of Presentation
  the Matrix, Biopolis, Singapore.
- Year and Date
  2008-09-03
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Neural differentiation and cell therapy using pluripotent stem cells2008
- Author(s)
  Hideyuki Okano
- Organizer
  2^<nd> Symposium on Brain and Mind Research in the Asia / Pacific (BMAP)
- Place of Presentation
  the Matrix, Biopolis, Si ngapore
- Year and Date
  2008-09-03
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Regeneration of the damaged CNS using stem cells2008
- Author(s)
  Okano H.
- Organizer
  Neural Stem Cells & Regenarative Neuroscience Workshop
- Place of Presentation
  Scientia Building, UNSW, Sydney Australia
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Neural differentiation of pluripotent stem cells based therapy for spinal cord injury, the National Centre for Adult Stem Cell Research conference2008
- Author(s)
  H. Okano
- Organizer
  Adult Stem Cells - Biology and Clinical Applications Meeting
- Place of Presentation
  Griffith University, Queensland, Australia
- Year and Date
  2008-11-27
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Neural differentiation of pluripotent stem cells based therapy for spinal cord injury2008
- Author(s)
  Okano H.
- Organizer
  the National Centre for Adult Stem Cell Research conference, Adult Stem Cells - Biology and Clinical Applications Meeting
- Place of Presentation
  Griffith University, Queensland, Australia
- Year and Date
  2008-11-27
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Strategies for the regeneration of damaged CNS2008
- Author(s)
  Hideyuki Okano
- Organizer
  The 17^<th> Biennial Meeting of the International Society for Developmental Neuroscience
- Place of Presentation
  Asilomar, CA, U.S.A.
- Year and Date
  2008-06-03
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Neural differentiation of pluripotent stem cells based therapy for spinal cord injury2008
- Author(s)
  Hideyuki Okano
- Organizer
  the National Centre for Adult Stem Cell Research conference, Adult Stem Cells-Biology and Clinical Applications Meeting
- Place of Presentation
  Griffith University, Que ensland, Australia
- Year and Date
  2008-11-27
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Neural Stem Cells: their involvement in adult neurogenesis and CNS-repair2007
- Author(s)
  Okano, H.
- Organizer
  Stem Cells and CNS Regeneration (Symposium by biosymposia, Inc. )
- Place of Presentation
  Boston, USA.
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Neural Stem Cells: their involvement in adult neurogenesis and CNS-repair2007
- Author(s)
  Okano, H.
- Organizer
  8th World Congress on Inflammation
- Place of Presentation
  Copenhagen, Denmark.
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] A rol of neuronal RNA binding protein Hu and NF45/90 in the nervous system.2007
- Author(s)
  Okano, HJ., Igarashi, M., Yano, M.& Okano, H.
- Organizer
  2007 Annual Meeting of the Society For Nuroscience
- Place of Presentation
  San Diego, USA.
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Molecular Identification of Neural Stem Cell Self-renewing Factor2007
- Author(s)
  Okano, H.
- Organizer
  4th Annual Christopher Reeve "HOT TOPICS" IN STEM CELL BIOLOGY, Satellite Symposium at the 2007 Annual Meeting of the Society For Nuroscience
- Place of Presentation
  San Diego, USA.
- Year and Date
  2007-11-15
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Neural Stem Cells: their involvement in adult neurogenesis and CNS-repair.2007
- Author(s)
  Okano. H.
- Organizer
  8th World Congress on Inflammation
- Place of Presentation
  Copenhagen, Denmark.
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Impaired axonal transport in Purkinje cells of HuC knockout mice
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  米国神経科学会
- Place of Presentation
  Walter E Washington Convention Center, Washington D. C. U.S.A.
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-24300122
[Presentation] 小脳プルキンエ細胞におけるHuC依存的軸索輸送機構
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第３７回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24300122
[Presentation] Multimodal and exclusive pathology between ALS and FTLD caused by TDP-43 mutations
- Author(s)
  Hara-Miyauchi C, Date Y, Hasegawa M, Kobayashi R, Fujigasaki J, Kogo N, Sano C, Kobayashi Y, Suzuki N, Itohara S, Okano H, Okano HJ
- Organizer
  米国神経科学会
- Place of Presentation
  Walter E Washington Convention Center, Washington D. C. U.S.A.
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-24300122
[Presentation] Development of biomarkers in peripheral blood cells of ALS model mice.
- Author(s)
  Hasegawa M, Hara-Miyauchi C, Okano HJ
- Organizer
  米国神経科学会
- Place of Presentation
  Walter E Washington Convention Center, Washington D. C. U.S.A.
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-24300122
[Presentation] Impaired axonal transport in Purkinje cells of HuC knockout mice
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  米国神経科学会
- Place of Presentation
  Walter E Washington Convention Center, Washington D. C. U.S.A.
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PUBLICLY-26111723
[Presentation] 小脳プルキンエ細胞におけるHuC依存的軸索輸送機構
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第３７回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PUBLICLY-26111723

1. OKANO Hideyuki (60160694)

# of Collaborated Projects: 4 results

# of Collaborated Products: 55 results
2. Fujioka Masato (70398626)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. OGAWA Kaoru (00169179)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
4. 水足邦雄 (40338140)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 細谷誠 (30645445)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. 多田敬典 (20464993)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. 畑純一 (00568868)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. 白川崇子 (40218045)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 関根紀夫 (70295434)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 松浦勉 (80181692)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 古川顕 (80199421)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 山田惠 (80315960)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. HARA Chikako (40528452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. AKAMATSU Wado (60338184)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NAKAO Yasushi (30188883)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NISHIWAKI Masao (90296640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TAKAYAMA Shinichiro (40138045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MORISAWA Yasushi (60306751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MATSUSHITA Masayuki (30273965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 原田竜彦 (60238186)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 鷹橋浩幸 (00246414)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 早川朋子 (30420821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 小澤宏之 (30327621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 疋島啓吾 (30420219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 鄭雅誠 (50792272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 栗原渉 (90826926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. 酒井晃二 (20379027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. MIYAZAKI Taisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. KUWAKO Ken-ichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
30. SAITO Shigeyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. FUKUCHI Kazuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. OISHI Naoki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. NISHIMOTO Yoshinori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. NAKANISHI Hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. ARIMITSU Nagisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 矢野真人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 吉田哲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 平井宏和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 今野歩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 松本啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
41. 山中修一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
42. 樋口隆弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 木村実

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 長谷川寿一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 狩野方伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 青木茂樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 長谷川成人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 崎村建司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 横尾隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 神崎晶

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 芝田晋介

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
52. 中川真一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 今井貴雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 多賀谷光男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okano James Hirotaka 岡野 ジェイムス洋尚

OKANO Hirotaka James 岡野 ジェイムス洋尚

OKANO James Hirotaka 岡野 ジェイムス洋尚

岡野 ジェームス洋尚 オカノ ジェームスヒロタカ

Research Projects

Research Products

Co-Researchers

家族性パーキンソン病PARK17由来iPS細胞を用いた根幹病態の解明と治療薬開発Principal InvestigatorOngoing

Principal Investigator

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NIRSを用いた高次脳活動時の脳血液量増加持続時間の解析Ongoing

Principal Investigator

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Review Section

Research Institution

Development of novel therapeutics for the cochlear hearing impairments by using hiPSCs and common marmoset modelsOngoing

Principal Investigator

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Review Section

Research Institution

Influence of high concentrated oxygen inhalation on cerebral blood flow during higher brain functioningOngoing

Principal Investigator

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Review Section

Research Institution

AR-navigated transcanal endoscopic inner ear sugery

Principal Investigator

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Establishment of RNA-based Biomarkers for ALSPrincipal Investigator

Principal Investigator

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Visualizing the olfactory map with diffusion tensor imaging: Development of an objective olfactory test methodOngoing

Principal Investigator

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Pre-clinical proof of concept trials for auditory hair cell regeneration by using hiPSC technology and marmoset model

Principal Investigator

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Pathogenesis of schizophrenia using neural induction system from iPS Cell

Principal Investigator

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Effects of high-energy particles on neural activityPrincipal Investigator

Principal Investigator

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遅発性小脳失調モデル動物を用いた軸索変性機序の解明Principal Investigator

Principal Investigator

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Review Section

Research Institution

遅発性小脳失調モデル動物を用いた軸索変性機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analyses of regulatory mechanisms of TDP-43 level and risk factor of ALSPrincipal Investigator

Okano James Hirotaka 岡野ジェイムス洋尚

OKANO Hirotaka James 岡野ジェイムス洋尚

OKANO James Hirotaka 岡野ジェイムス洋尚

岡野ジェームス洋尚オカノジェームスヒロタカ

[Book] 神経科学の最前線とリハビリテーション　脳の可塑性と運動2015