Okano James Hirotaka 岡野ジェイムス洋尚

… Alternative Names

OKANO Hirotaka James 岡野ジェイムス洋尚

OKANO James Hirotaka 岡野ジェイムス洋尚

岡野ジェームス洋尚オカノジェームスヒロタカ

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Researcher Number	90338020
Other IDs
Affiliation (Current)	2025: 東京慈恵会医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2012 – 2025: 東京慈恵会医科大学, 医学部, 教授 2007 – 2010: Keio University, 医学部, 准教授 2009: 医学部, 准教授 2004 – 2006: 慶應義塾大学, 医学部, 助教授 2002 – 2003: 慶應義塾大学, 医学部, 専任講師 2002 – 2003: 慶應義塾大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Biological Sciences / Biological Sciences / Basic Section 46010:Neuroscience-general-related / Basic Section 51030:Pathophysiologic neuroscience-related / Neurology / Environmental physiology(including physical medicine and nutritional physiology) / Neuroscience in general / Neurology / Neuroscience in general Except Principal Investigator Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields … More / Basic Section 55030:Cardiovascular surgery-related / Basic Section 52040:Radiological sciences-related / Surgery related to the biological and sensory functions and related fields / Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Otorhinolaryngology / General physiology / Orthopaedic surgery / Biological Sciences Less
Keywords	Principal Investigator RNA結合タンパク質 / Hu / 神経変性疾患 / 神経細胞 / 翻訳調節 / レトロマー / パーキンソン病 / hnRNP K / translational control / paraneoplastic neurologic disorders … More / RNA binding protein / 神経分化 / p27Kip1 / 傍腫瘍性脳脊髄症 / TDP-43 / ALS / 軸索輸送 / 神経伝達物質 / シナプス / タンパク質分解 / ユビキチンリガーゼ / VPS29 / リソゾーム / iPS細胞 / αシヌクレイン / Rab9 / 新規オートファジー / VPS35 / RNA代謝 / バイオマーカー / 選択的スプライシング / 宇宙放射線 / neural stem cell / neuronal differentiation / 遺伝子改変動物 / 神経幹細胞 / hnRNPK / neural differentiation / IRES dependent translation / IRES依存的翻訳 / 細胞質・軸索間拡散障壁 / 小脳失調 / 神経科学 / 小脳 / Fbxo45 / Kspot / Ksot / 乳癌 / 非翻訳領域 / 肺非小細胞癌 / 癌危険度 / SNP / p27 Kip1 … More Except Principal Investigator 耳科学 / 霊長類研究 / 橋渡し研究 / 聴覚医学 / 内耳再生 / 超音波造影剤 / 血栓溶解 / 霊長類モデル / hiPS細胞 / マーモセット / RBP / スプライスバリアント / TDP-43 / ALS / 臨床用汎用型超音波装置 / ステントグラフト / 間葉系幹細胞 / 大動脈解離 / 大動脈瘤 / 幹細胞ファイバー / Caイメージング / 聴覚 / 脳科学 / コモンマーモセット / in vivoイメージング / 脳機能ネットワーク / 聴覚伝導路 / マウスモデル / 精神発達遅滞 / iPS細胞由来神経細胞 / RBM10 / TARP症候群 / 患者由来iPS細胞 / 疾患iPS細胞 / Rbm10-KOマウス / IoTセンシング / 内耳性難聴 / バイオインフォマティクス / 聴覚障害 / iPS細胞創薬 / contrast agent / ultrasound / micro bubble / thrombolysis / thrombosis / 臨床用汎用型超音波診断装置 / カラードプラ / Bモード / 超音波 / 血栓 / 顔面神経麻痺 / 内視鏡下耳科手術 / 拡張現実 / 難聴医学 / 医用画像読影 / 近赤外分光分析 / 脳血液量増加持続時間 / 脳血流量変化 / 近赤外分光解析法 / 実技実習 / 医療スキル / 注視点計測 / oxygen inspiration / 高濃度酸素吸入 / 高次脳活動 / fMRI / 一桁暗算 / 酸素吸入 / 脳活動 / NIRS / oxygen inhalation / prefrontal cortex / reserve capacity / calculation / fNIRS / 疾患特異的iPS / iPS創薬スクリーニング / トランスレーショナルリサーチ / 橋渡し研究加速 / iPS細胞スクリーニング / ヒトiPS細胞 / 再生医療 / 匂いの地図 / DTI / 嗅覚 / 拡散テンソルイメージング / 高磁場MRI機 / 嗅神経分布 / 嗅神経地図 / 嗅上皮 / 嗅球 / トラクトグラフィー / 嗅神経 / mood disorder / schizophrenia / iPS / ゲノム解析 / iPS細胞 / iPSC / ゲノム / 家系 / 統合失調症 / 精神疾患 / nerve graft / artificial nerve / Schwann cell / ティッシュエンジニアリング / 末梢神経 / 再生医学 / 組織工学 / 神経移植 / 人工神経 / Schwann細胞 / RNA結合タンパク / IP3受容体 / p21Cipl / Musashi / 翻訳調 / Hzf / Hu / p21Cip1 / Hu Hzf Musashi / 神経分化 / 翻訳調節 / 神経幹細胞 / RNA結合タンパク質 / 分子・細胞神経科学 Less

Regulatory mechanisms of neuronal retromerPrincipal Investigator
- Principal Investigator
  
  岡野ジェイムス洋尚
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Jikei University School of Medicine
New endovascular treatment strategy for aortic disease: possibility of transcatheter regenerative therapy using a cell fiber technology
- Principal Investigator
  
  福島宗一郎
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Jikei University School of Medicine
Enhancement of Thrombolysis in Vascular Access Thrombosis for Hemodialysis Using Ultrasound Irradiation with Ultrasound Contrast Agents
- Principal Investigator
  
  笠兼太朗
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Jikei University School of Medicine
ALSにおける運動ニューロン特異的スプライシング制御機構の解明
- Principal Investigator
  
  長谷川実奈美
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Jikei University School of Medicine
TARP症候群のiPS細胞および動物モデルを用いた神経学的症状の病態解明
- Principal Investigator
  
  大石公彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Jikei University School of Medicine
Integrated understanding of the brain network: from auditory perception
- Principal Investigator
  
  藤岡正人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kitasato University
Pathophysiological analysis of Parkinson's Disease using PARK17 patient-derived iPS cellPrincipal Investigator
- Principal Investigator
  
  Okano Hirotaka James
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Jikei University School of Medicine
Enhancing thrombolytic therapy using clinical ultrasound with micro bubble contrast agent
- Principal Investigator
  
  白川崇子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Tokyo Metropolitan University
Integrated understanding of inner ear disorders and next-generation drug discovery by combination of IoT sensing and iPSC-based medicine
- Principal Investigator
  
  Fujioka Masato
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kitasato University
NIRSを用いた高次脳活動時の脳血液量増加持続時間の解析
- Principal Investigator
  
  関根紀夫
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Tokyo Metropolitan University
Influence of high concentrated oxygen inhalation on cerebral blood flow during higher brain functioning
- Principal Investigator
  
  Shirakawa Takako
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Tokyo Metropolitan University
Development of novel therapeutics for the cochlear hearing impairments by using hiPSCs and common marmoset models
- Principal Investigator
  
  FUJIOKA Masato
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Keio University
Establishment of RNA-based Biomarkers for ALSPrincipal Investigator
- Principal Investigator
  
  Okano Hirotaka James
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Jikei University School of Medicine
Visualizing the olfactory map with diffusion tensor imaging: Development of an objective olfactory test method
- Principal Investigator
  
  Tei Masayoshi
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Surgery related to the biological and sensory functions and related fields
- Research Institution
  Jikei University School of Medicine
AR-navigated transcanal endoscopic inner ear sugery
- Principal Investigator
  
  OGAWA Kaoru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Surgery related to the biological and sensory functions and related fields
- Research Institution
  Keio University
Pathogenesis of schizophrenia using neural induction system from iPS Cell
- Principal Investigator
  
  MATSUSHITA Masayuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  University of the Ryukyus
Effects of high-energy particles on neural activityPrincipal Investigator
- Principal Investigator
  
  Okano Hirotaka James
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Jikei University School of Medicine
Pre-clinical proof of concept trials for auditory hair cell regeneration by using hiPSC technology and marmoset model
- Principal Investigator
  
  Fujioka Masato
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Keio University
遅発性小脳失調モデル動物を用いた軸索変性機序の解明Principal Investigator
- Principal Investigator
  
  岡野ジェイムス洋尚
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Jikei University School of Medicine
遅発性小脳失調モデル動物を用いた軸索変性機序の解明Principal Investigator
- Principal Investigator
  
  岡野ジェイムス洋尚
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Jikei University School of Medicine
Analyses of regulatory mechanisms of TDP-43 level and risk factor of ALSPrincipal Investigator
- Principal Investigator
  
  OKANO Hirotaka James
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Jikei University School of Medicine
神経特異的ユビキチンリガーゼKspotによるシナプス制御Principal Investigator
- Principal Investigator
  
  岡野ジェイムス洋尚
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
中枢神経特異的ユビキチンリガーゼKspotによるシナプス制御Principal Investigator
- Principal Investigator
  
  岡野ジェイムス洋尚
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
Regulation of neuronal differentiation and plasticity at posttranscriptional level
- Principal Investigator
  
  OKANO Hideyuki
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
p27Kipl mRNA非翻訳領域SNPと翻訳促進活性・癌危険度との関連Principal Investigator
- Principal Investigator
  
  岡野ジェイムス洋尚
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
The Role of RNA Binding Protein Hu in Neuronal DifferentiationPrincipal Investigator
- Principal Investigator
  
  OKANO Hirotaka, James
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Keio University
The Role of RNA Binding Protein Hu in pathophysiology of the paraneoplastic neurologic disorders (PND's)Principal Investigator
- Principal Investigator
  
  OKANO Hirotaka james
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  KEIO UNIVERSITY
Experimental studies on peripheral nerve regeneration through the bio-nerve with 3D cultured Schwann cell
- Principal Investigator
  
  NAKAO Yasushi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  KEIO UNIVERSITY

[Book] The 3-Dimensional Atlas of the Marmoset Brain: Reconstructible in Stereotaxic Coordinates (Brain Science).2019
- Author(s)
  Iriki A, Okano HJ, Sasaki E, Okano H.
- Total Pages
  399
- Publisher
  Springer
- ISBN
  9784431566106
- Data Source
  KAKENHI-PROJECT-17K09766
[Book] 神経科学の最前線とリハビリテーション　脳の可塑性と運動2015
- Author(s)
  岡野ジェイムス洋尚
- Total Pages
  272
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PUBLICLY-26111723
[Book] 遺伝子医学 MOOK 26号「脳内環境―維持機構と破綻がもたらす疾患研究」2014
- Author(s)
  岡野ジェイムス洋尚
- Total Pages
  228
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PROJECT-24300122
[Book] 遺伝子医学 MOOK 26号「脳内環境―維持機構と破綻がもたらす疾患研究」2014
- Author(s)
  岡野ジェイムス洋尚
- Total Pages
  228
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PUBLICLY-26111723
[Book] Functions of neural RNA-binding proteins Musashi and Hu in stem cells and neuronal differentiation. RNA Binding Proteins in Development and Disease. (Edited by Robert B. Denman)2008
- Author(s)
  Kawahara, H., Yano, M., Imai, T., Akamatsu, W., Okano, HJ., Okano, H.
- Publisher
  Research Signpost, Kerala
- Data Source
  KAKENHI-PROJECT-17024051
[Book] Tissue Stem Cells ; Biology & Applications.2005
- Author(s)
  Okano H. et al.
- Total Pages
  383
- Publisher
  Taylor & Francis Group, New York
- Data Source
  KAKENHI-PROJECT-16500206
[Book] Tissue Stem Cells; Biblogy & Applicatibns.2005
- Author(s)
  Okano H. et al.
- Total Pages
  383
- Publisher
  Taylor & Francis Group, New York
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500206
[Journal Article] The impact of VPS35 D620N mutation on alternative autophagy and its reversal by estrogen in Parkinson's disease2024
- Author(s)
  Tomotaka Shiraishi, Keiko Bono, Hiromi Hiraki, Yoko Manome, Hisayoshi Oka, Yasuyuki Iguchi, Hirotaka James Okano
- Journal Title
  
  Cellular and Molecular Life Sciences
  
  Volume: 81 Issue: 1 Pages: 103-103
- DOI
  10.1007/s00018-024-05123-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15719, KAKENHI-PROJECT-21K07302, KAKENHI-PROJECT-18K15468, KAKENHI-PROJECT-22KJ2783
[Journal Article] Specific vulnerability of iPSC-derived motor neurons with TDP-43 gene mutation to oxidative stress2023
- Author(s)
  Asako Onda-Ohto, Minami Hasegawa-Ogawa, Hiromasa Matsuno, Tomotaka Shiraishi, Keiko Bono, Hiromi Hiraki, Yumi Kanegae, Yasuyuki Iguchi, Hirotaka James Okano
- Journal Title
  
  Molecular Brain
  
  Volume: 16 Issue: 1 Pages: 62-62
- DOI
  10.1186/s13041-023-01050-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15719, KAKENHI-PROJECT-22K20696, KAKENHI-PROJECT-23K06812, KAKENHI-PROJECT-18K15468
[Journal Article] Interactive effect of orthostatic hypotension on gray matter atrophy associated with hyposmia and RBD in de novo Parkinson's disease2023
- Author(s)
  Shiraishi T, Yoshimaru D, Umehara T, Ozawa M, Omoto S, Okumura M, Kokubu T, Takahashi J, Sato T, Onda A, Komatsu T, Sakai K, Mitsumura H, Murakami H, Okano HJ, Iguchi Y.
- Journal Title
  
  Journal of Neurology
  
  Volume: 270 Issue: 12 Pages: 5924-5934
- DOI
  10.1007/s00415-023-11934-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07302, KAKENHI-PROJECT-22KJ2783
[Journal Article] Generation of two induced pluripotent stem cell lines from individuals without auditory disorders2023
- Author(s)
  Okura Shota、Ishii Honoka、Suzuki Ayano、Saegusa Chika、Fujiki Ko、Sugano Kenshi、Suzuki Noriomi、Saeki Tsubasa、Matsuzaki Saeko、Ozawa Hiroyuki、Fujioka Masato、Hosoya Makoto、Okano Hideyuki
- Journal Title
  
  Stem Cell Research
  
  Volume: 67 Pages: 103017-103017
- DOI
  10.1016/j.scr.2023.103017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20409, KAKENHI-PROJECT-21H04839
[Journal Article] Critical roles of FGF, RA, and WNT signaling in the development of human otic placode and subsequent lineages in a dish2022
- Author(s)
  Saeki, T., Yoshimatsu, S., Ishikawa, M., Shin, JW., Hon, C-C., Shibata, S., Hosoya, M., Saegusa, C., Ogawa, K., Fujioka, M., Okano, H.
- Journal Title
  
  Regen Ther
  
  Volume: 20 Pages: 165-186
- DOI
  10.1016/j.reth.2022.04.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K24038, KAKENHI-PROJECT-20K20409, KAKENHI-PROJECT-21H04839, KAKENHI-PROJECT-21K15112
[Journal Article] Otic Organoids Containing Spiral Ganglion Neuron-like Cells Derived from Human-induced Pluripotent Stem Cells as a Model of Drug-induced Neuropathy2022
- Author(s)
  Kurihara Sho、Fujioka Masato、Hirabayashi Motoki、Yoshida Tomohiko、Hosoya Makoto、Nagase Masashi、Kato Fusao、Ogawa Kaoru、Okano Hideyuki、Kojima Hiromi、Okano Hirotaka James
- Journal Title
  
  Stem Cells Translational Medicine
  
  Volume: 11 Issue: 3 Pages: 282-296
- DOI
  10.1093/stcltm/szab023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04065, KAKENHI-PROJECT-20K20409, KAKENHI-PROJECT-22K18399, KAKENHI-PROJECT-21H04839
[Journal Article] 小型霊長類コモンマーモセットを用いた聴覚研究2022
- Author(s)
  栗原渉、岡野ジェイムス洋尚、藤岡正人
- Journal Title
  
  BIO Clinica
  
  Volume: 37-2 Pages: 91-93
- Data Source
  KAKENHI-PROJECT-18H04065
[Journal Article] MRI tractography reveals the human olfactory nerve map connecting the olfactory epithelium and olfactory bulb2022
- Author(s)
  Sho Kurihara, Masayoshi Tei, Junichi Hata, Eri Mori, Masato Fujioka, Yoshinori Matsuwaki, Nobuyoshi Otori, Hiromi Kojima, Hirotaka James Okano
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 843-843
- DOI
  10.1038/s42003-022-03794-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09568, KAKENHI-PROJECT-21H04839, KAKENHI-PROJECT-20H03630, KAKENHI-PROJECT-17K19735
[Journal Article] 小型霊長類コモンマーモセットを用いた聴覚研究2022
- Author(s)
  栗原渉、岡野ジェイムス洋尚、藤岡正人
- Journal Title
  
  BIO Clinica
  
  Volume: 37-2 Pages: 91-93
- Data Source
  KAKENHI-PROJECT-21H04839
[Journal Article] Early development of the cochlea of the common marmoset, a non-human primate model2022
- Author(s)
  Hosoya Makoto、Fujioka Masato、Okahara Junko、Yoshimatsu Sho、Okano Hideyuki、Ozawa Hiroyuki
- Journal Title
  
  Neural Development
  
  Volume: 17 Issue: 1 Pages: 6-6
- DOI
  10.1186/s13064-022-00162-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04839, KAKENHI-PROJECT-20H03836, KAKENHI-PROJECT-21K19581, KAKENHI-PROJECT-21K15112
[Journal Article] Author Correction: MRI tractography reveals the human olfactory nerve map connecting the olfactory epithelium and olfactory bulb2022
- Author(s)
  Kurihara Sho、Tei Masayoshi、Hata Junichi、Mori Eri、Fujioka Masato、Matsuwaki Yoshinori、Otori Nobuyoshi、Kojima Hiromi、Okano Hirotaka James
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 1219-1219
- DOI
  10.1038/s42003-022-04220-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04839
[Journal Article] α-Synuclein-mediated neurodegeneration in Dementia with Lewy bodies: the pathobiology of a paradox2021
- Author(s)
  Simon Christopher、Soga Tomoko、Okano Hirotaka James、Parhar Ishwar
- Journal Title
  
  Cell & Bioscience
  
  Volume: 11 Issue: 1 Pages: 196-196
- DOI
  10.1186/s13578-021-00709-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07302
[Journal Article] Characterization of the upstream and intron promoters of the gene encoding TAR DNA-binding protein2021
- Author(s)
  Minami Hasegawa-Ogawa, Hirotaka James Okano
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 8720-8720
- DOI
  10.1038/s41598-021-88015-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15904, KAKENHI-PROJECT-21K07302
[Journal Article] Neuronal development in the cochlea of a nonhuman primate model, the common marmoset2021
- Author(s)
  Hosoya Makoto、Fujioka Masato、Murayama Ayako Y、Ozawa Hiroyuki、Okano Hideyuki、Ogawa Kaoru
- Journal Title
  
  Developmental Neurobiology
  
  Volume: 81 Issue: 8 Pages: 905-938
- DOI
  10.1002/dneu.22850
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04065, KAKENHI-PROJECT-20H03836, KAKENHI-PROJECT-21K19581, KAKENHI-PROJECT-21H04839
[Journal Article] Dynamic Spatiotemporal Expression Changes in Connexins of the Developing Primate’s Cochlea2021
- Author(s)
  Hosoya Makoto、Fujioka Masato、Murayama Ayako Y.、Ogawa Kaoru、Okano Hideyuki、Ozawa Hiroyuki
- Journal Title
  
  Genes
  
  Volume: 12 Issue: 7 Pages: 1082-1082
- DOI
  10.3390/genes12071082
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04065, KAKENHI-PROJECT-20H03836, KAKENHI-PROJECT-21K19581, KAKENHI-PROJECT-21H04839
[Journal Article] Distribution of tight junctions in the primate cochlear lateral wall2020
- Author(s)
  Saeki Tsubasa、Hosoya Makoto、Shibata Shinsuke、Okano Hideyuki、Fujioka Masato、Ogawa Kaoru
- Journal Title
  
  Neuroscience Letters
  
  Volume: 717 Pages: 134686-134686
- DOI
  10.1016/j.neulet.2019.134686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04065
[Journal Article] Generation of a human iPS cell line (CGMH.SLC26A4919-2) from a Pendred syndrome patient carrying SLC26A4 c.919-2A>G splice-site mutation.2019
- Author(s)
  Cheng YF, Chan YH, Hu CJ, Lu YC, Saeki T, Hosoya M, Saegusa C, Fujioka M, Okano H, Weng SM, Hsu CJ, Chang KH, Wu CC.
- Journal Title
  
  Stem Cell Res.
  
  Volume: 40 Pages: 101524-101524
- DOI
  10.1016/j.scr.2019.101524
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K24038, KAKENHI-PROJECT-18H04065
[Journal Article] Neurite orientation dispersion and density imaging for evaluating the severity of neonatal hypoxic-ischemic encephalopathy in rats2019
- Author(s)
  Ohki Akiko、Saito Shigeyoshi、Hata Junichi、Okano Hirotaka James、Higuchi Takahiro、Fukuchi Kazuki
- Journal Title
  
  Magnetic Resonance Imaging
  
  Volume: 62 Pages: 214-219
- DOI
  10.1016/j.mri.2019.07.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08172, KAKENHI-PROJECT-19K17254, KAKENHI-PROJECT-17K09766, KAKENHI-PROJECT-17K10421, KAKENHI-PROJECT-15K21774
[Journal Article] In vivo regeneration of interspecies chimeric kidneys using a nephron progenitor cell replacement system2019
- Author(s)
  Fujimoto Toshinari、Yamanaka Shuichiro、Tajiri Susumu、Takamura Tsuyoshi、Saito Yatsumu、Matsumoto Kei、Takase Kentaro、Fukunaga Shohei、Okano Hirotaka James、Yokoo Takashi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 6965-6965
- DOI
  10.1038/s41598-019-43482-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17756, KAKENHI-PROJECT-16K09630, KAKENHI-PROJECT-17K09766, KAKENHI-PROJECT-17K16102
[Journal Article] Anatomical and Surgical Evaluation of the Common Marmoset as an Animal Model in Hearing Research.2019
- Author(s)
  Kurihara S, Fujioka M, Hata J, Yoshida T, Hirabayashi M, Yamamoto Y, Ogawa K, Kojima H, Okano HJ.
- Journal Title
  
  Frontiers in Neuroanatomy
  
  Volume: 13 Pages: 60-60
- DOI
  10.3389/fnana.2019.00060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09766, KAKENHI-PROJECT-17K10421, KAKENHI-PROJECT-19K21357, KAKENHI-PROJECT-18H04065
[Journal Article] Elavl3 regulates neuronal polarity through the alternative splicing of an embryo-specific exon in AnkyrinG.2018
- Author(s)
  Ogawa Y, Yamaguchi J, Yano M, Uchiyama Y, Okano HJ
- Journal Title
  
  Neurosci Res.
  
  Volume: - Pages: 13-20
- DOI
  10.1016/j.neures.2018.03.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16J11920, KAKENHI-PROJECT-17K09766, KAKENHI-PUBLICLY-17H05598, KAKENHI-PROJECT-16K07247
[Journal Article] A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset (Callithrix jacchus).2018
- Author(s)
  Kurihara S, Fujioka M, Yoshida T, Koizumi M, Ogawa K, Kojima H, Okano HJ.
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 132 Issue: 132 Pages: 132-132
- DOI
  10.3791/56574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09766, KAKENHI-PROJECT-15H04991
[Journal Article] Estimating the concentration of therapeutic range using disease-specific iPS cells: Low-dose rapamycin therapy for Pendred syndrome2018
- Author(s)
  Hosoya M, Saeki T, Saegusa C, Matsunaga T, Okano H, Fujioka M, Ogawa K.
- Journal Title
  
  Regen Ther
  
  Volume: 17;10 Pages: 54-63
- DOI
  10.1016/j.reth.2018.11.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04065, KAKENHI-PROJECT-17K19733
[Journal Article] Elavl3 is essential for the maintenance of Purkinje neuron axons2018
- Author(s)
  Ogawa Yuki、Kakumoto Kyoko、Yoshida Tetsu、Kuwako Ken-ichiro、Miyazaki Taisuke、Yamaguchi Junji、Konno Ayumu、Hata Junichi、Uchiyama Yasuo、Hirai Hirokazu、Watanabe Masahiko、Darnell Robert B.、Okano Hideyuki、Okano Hirotaka James
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 2722-2722
- DOI
  10.1038/s41598-018-21130-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08485, KAKENHI-PROJECT-17K09766, KAKENHI-PROJECT-16J11920, KAKENHI-PROJECT-15K06807, KAKENHI-PROJECT-16K14581, KAKENHI-PROJECT-16K15477, KAKENHI-PROJECT-15K18330
[Journal Article] 【脳タンパク質老化と認知症制御】 iPSC及びマーモセットモデルを用いたPendred症候群のヒト特異的病態の解明と治療法開発2018
- Author(s)
  佐伯翼，藤岡正人，岡野栄之
- Journal Title
  
  細胞
  
  Volume: 50巻6号 Pages: 315-318
- Data Source
  KAKENHI-PROJECT-18H04065
[Journal Article] Expression Pattern of EYA4 in the common marmoset (Callithrix jacchus) cochlea.2018
- Author(s)
  Saeko Matsuzaki, Makoto Hosoya, Hideyuki Okano, Masato Fujioka, Kaoru Ogawa
- Journal Title
  
  Neuroscience Letters
  
  Volume: 662 Pages: 185-188
- DOI
  10.1016/j.neulet.2017.10.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K20276, KAKENHI-PROJECT-15H04991
[Journal Article] Visualization of nerve fibers around the carotid bifurcation using a 9.4 T microscopic magnetic resonance (MR) diffusion tensor imaging with tractography.2018
- Author(s)
  Saito S, Ozawa H, Fujioka M, Hikishima K, Hata J, Kurihara S, Okano H, Ogawa K
- Journal Title
  
  Head ＆ Neck
  
  Volume: ー
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19732
[Journal Article] Regenerative potential of induced pluripotent stem cells derived from patients undergoing haemodialysis in kidney regeneration2018
- Author(s)
  Tajiri Susumu、Yamanaka Shuichiro、Fujimoto Toshinari、Matsumoto Kei、Taguchi Atsuhiro、Nishinakamura Ryuichi、Okano Hirotaka James、Yokoo Takashi
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41598-018-33256-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09630, KAKENHI-PROJECT-17K09766, KAKENHI-PROJECT-17K16102, KAKENHI-PROJECT-16H03175, KAKENHI-PROJECT-19K21307
[Journal Article] Loss of DDHD2, whose mutation causes spastic paraplegia, promotes reactive oxygen species generation and apoptosis2018
- Author(s)
  Maruyama Tomohiro、Baba Takashi、Maemoto Yuki、Hara-Miyauchi Chikako、Hasegawa-Ogawa Minami、Okano Hirotaka James、Enda Yuki、Matsumoto Kei、Arimitsu Nagisa、Nakao Kazuki、Hamamoto Hiroshi、Sekimizu Kazuhisa、Ohto-Nakanishi Takayo、Nakanishi Hiroki、Tokuyama Takeshi、Yanagi Shigeru、Tagaya Mitsuo、Tani Katsuko
- Journal Title
  
  Cell Death & Disease
  
  Volume: 9 Issue: 8 Pages: 797-811
- DOI
  10.1038/s41419-018-0815-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07194, KAKENHI-PROJECT-17K09766, KAKENHI-PROJECT-17K10852, KAKENHI-PROJECT-18H02439
[Journal Article] 小型霊長類コモンマーモセットの側頭骨局所解剖に関する画像解析2017
- Author(s)
  藤岡正人, 疋島啓吾, 岡野ジェイムス洋尚, 若林健一郎, 山田雅之, 大石直樹, 畑純一, 小川郁
- Journal Title
  
  Otology Japan
  
  Volume: 27巻5号 Pages: 680-688
- NAID
  130007595705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04991
[Journal Article] Generation of interspecies limited chimeric nephrons using a conditional nephron progenitor cell replacement system.2017
- Author(s)
  Yamanaka S, Tajiri S, Fujimoto T, Matsumoto K, Fukunaga S, Kim BS, Okano HJ, Yokoo T.
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 1719-1732
- DOI
  10.1038/s41467-017-01922-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09630, KAKENHI-PROJECT-17K09766, KAKENHI-PROJECT-17K16102
[Journal Article] Cochlear Cell Modeling Using Disease-Specific iPSCs Unveils a Degenerative Phenotype and Suggests Treatments for Congenital Progressive Hearing Loss2017
- Author(s)
  Makoto Hosoya, Masato Fujioka, Takefumi Sone, Satoshi Okamoto, Wado Akamatsu, Hideki Ukai, Hiroki R. Ueda, Kaoru Ogawa, Tatsuo Matsunaga, Hideyuki Okano
- Journal Title
  
  Cell Reports
  
  Volume: 18 Issue: 1 Pages: 68-81
- DOI
  10.1016/j.celrep.2016.12.020
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06924, KAKENHI-PROJECT-15K15624, KAKENHI-PROJECT-26670748, KAKENHI-PROJECT-15H04991
[Journal Article] Overlapping expression of anion exchangers in the cochlea of a non-human primate suggests functional compensation.2016
- Author(s)
  Hosoya M, Fujioka M, Kobayashi R, Okano H, Ogawa K.
- Journal Title
  
  Neuroscience Research
  
  Volume: S0168-0102(16) Pages: 3000006-3000006
- DOI
  10.1016/j.neures.2016.04.002
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15624, KAKENHI-PROJECT-24592560, KAKENHI-PROJECT-15H04991
[Journal Article] Overlapping expression of anion exchangers in the cochlea of a non-human primate suggests functional compensation.2016
- Author(s)
  Hosoya M, Fujioka M, Kobayashi R, Okano H, Ogawa K.
- Journal Title
  
  Neuroscience Research
  
  Volume: S0168-0102(16) Pages: 300006-300006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04991
[Journal Article] Expression pattern of wolframin, the WFS1 (Wolfram syndrome-1 gene) product, in common marmoset (Callithrix jacchus) cochlea.2016
- Author(s)
  Suzuki N, Hosoya M, Oishi N, Okano H, Fujioka M, Ogawa K.
- Journal Title
  
  Neuroreport.
  
  Volume: 3;27(11) Issue: 11 Pages: 833-6
- DOI
  10.1097/wnr.0000000000000624
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15624, KAKENHI-PROJECT-16K20277, KAKENHI-PROJECT-15H04991
[Journal Article] Distinct Expression Patterns Of Causative Genes Responsible For Hereditary Progressive Hearing Loss In Non-Human Primate Cochlea.2016
- Author(s)
  Hosoya M, Fujioka M, Ogawa K, Okano H
- Journal Title
  
  Scientific Reports
  
  Volume: 26;6 Issue: 1 Pages: 22250-22250
- DOI
  10.1038/srep22250
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15624, KAKENHI-PROJECT-24592560, KAKENHI-PROJECT-15H04991
[Journal Article] Sustained Effect of Hyaluronic Acid in Subcutaneous Administration to the Cochlear Spiral Ganglion.2016
- Author(s)
  Inagaki Y, Fujioka M, Kanzaki S, Watanabe K, Oishi N, Itakura G, Yasuda A, Shibata S, Nakamura M, Okano HJ, Okano H, Ogawa K.
- Journal Title
  
  PLoS One in press
  
  Volume: 11 Issue: 4 Pages: e0153957-e0153957
- DOI
  10.1371/journal.pone.0153957
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10762, KAKENHI-PROJECT-15K15624, KAKENHI-PROJECT-15H04991, KAKENHI-PROJECT-26462714
[Journal Article] Distinct Expression Pattern of a Deafness Gene, KIAA1199, in a Primate Cochlea.2016
- Author(s)
  Hosoya M, Fujioka M, Okano H, Ogawa K.
- Journal Title
  
  Biomed Res Int
  
  Volume: 2016 Pages: 1781894-1781894
- DOI
  10.1155/2016/1781894
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04991
[Journal Article] Alternative role of HuD splicing variants in neuronal differentiation.2015
- Author(s)
  Hayashi S, Yano M, Igarashi M, Okano HJ, Okano H.
- Journal Title
  
  J Neurosci Res.
  
  Volume: 93 Issue: 3 Pages: 399-409
- DOI
  10.1002/jnr.23496
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24300122, KAKENHI-PUBLICLY-26111723, KAKENHI-PLANNED-26117007
[Journal Article] Analysis of RNA metabolism in peripheral WBCs of TDP-43 KI mice identifies novel biomarkers of ALS.2015
- Author(s)
  Hasegawa, M.;Hara-Miyauchi, C.;Ohta, H.;Sakimura, K.;Okano, H.;Okano, H. J.
- Journal Title
  
  Neurosci Res
  
  Volume: － Pages: 12-22
- DOI
  10.1016/j.neures.2015.11.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PUBLICLY-26111723, KAKENHI-PROJECT-26640007, KAKENHI-PLANNED-26117007
[Journal Article] Frontotemporal Dementia-associated N279K Tau Mutant Disrupts Subcellular Vesicle Trafficking and Induces Cellular Stress in iPSC-derived Neural Stem Cells.2015
- Author(s)
  Wren MC, Zhao J, Liu C-C, Murray ME, Atagi Y, Davis MD, Fu Y, Okano HJ, Ogaki K, Strongosky AJ, Tacik P, Rademakers R, Ross OA, Dickson DW, Wszolek ZK, Kanekiyo T, Bu G. 
- Journal Title
  
  Mol Neurodegener.
  
  Volume: 10 Issue: 1 Pages: 46-46
- DOI
  10.1186/s13024-015-0042-7
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26111723
[Journal Article] Proposing a new RNA quadruplex structure: j-motif, with possible links to neural development.2014
- Author(s)
  Nakamura S, Igarashi M, Kinoshita M, Okano HJ, Okano H.
- Journal Title
  
  Journal of Biochemistry
  
  Volume: 未定 Issue: 6 Pages: 385-392
- DOI
  10.1093/jb/mvu013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24111543, KAKENHI-PROJECT-24300122
[Journal Article] Fetal sulcation and gyrification in common marmosets (Callithrix Jacchus) obtained by ex vivo magnetic resonance imaging.2014
- Author(s)
  Sawada K, Hikishima K, Murayama AY, Okano HJ, Sasaki E, Okano H.
- Journal Title
  
  Neuroscience
  
  Volume: 257 Pages: 158-174
- DOI
  10.1016/j.neuroscience.2013.10.067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300122
[Journal Article] Cadherin-7 regulates the circuit connectivity of the cerebellar mossy fiber.2014
- Author(s)
  Kuwako K, Nishimoto Y, Kawase S, Okano HJ, Okano H.
- Journal Title
  
  Cell Rep.
  
  Volume: 9 Issue: 1 Pages: 331-323
- DOI
  10.1016/j.celrep.2014.08.063
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24300122, KAKENHI-PROJECT-25430073, KAKENHI-PUBLICLY-26111723, KAKENHI-PLANNED-26117007
[Journal Article] The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis2013
- Author(s)
  Nishimoto, Y., Nakagawa, S., Hirose, T., Okano, H. J., Takao, M., Shibata, S., Suyama, S., Kuwako, K., Imai, T., Murayama, S., Suzuki, N., and Okano, H
- Journal Title
  
  Mol. Brain
  
  Volume: 6 Issue: 1 Pages: 31-31
- DOI
  10.1186/1756-6606-6-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21228003, KAKENHI-PUBLICLY-24111543, KAKENHI-PROJECT-24300122, KAKENHI-PROJECT-24500447, KAKENHI-PROJECT-24601016, KAKENHI-PROJECT-25430073
[Journal Article] Kspot, a novel ubiquitin ligase, regulates synaptic activity.2010
- Author(s)
  Tada H., Okano HJ., Takagi H., Shibata S., Matsumoto M., Yao I., Saiga T., Nakayama KI., Kashima H., Takahashi T, Setou M, Okano H.
- Journal Title
  
  J.Biol.Chem. 285(6)
  
  Pages: 3840-3849
- NAID
  130005449632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Fbxo45, a novel ubiquitin ligase, regulates synaptic activity.2010
- Author(s)
  Tada H, Okano HJ, Takagi H, Shibata S, Yao I, Matsumoto M, Saiga T, Nakayama KI, Kashima H, Takahashi T, Setou M, Okano H.
- Journal Title
  
  J Biol Chem. 285
  
  Pages: 3840-3849
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025029
[Journal Article] Stromal cell-secreted factors promote the survival of ES cell-derived early neural stem/progenitor cells via the activation of MAPK and PI3K-Akt pathways.2010
- Author(s)
  Ishii S., Okada Y., Kadoya T., Matsuzaki Y., Shimazaki T., Okano H.
- Journal Title
  
  J.Neurosci.Res. 88(4)
  
  Pages: 722-773
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development.2009
- Author(s)
  Saiga T, Fukuda T, Matsumoto M, Tada H, Okano HJ, Okano H, Nakayama KI.
- Journal Title
  
  Mol Cell Biol. 29
  
  Pages: 3529-3543
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025029
[Journal Article] Precursor maintenance and GABAergic neuronal differentiation mediated by the PDK1-Akt pathway in mouse telencephalon.2009
- Author(s)
  Oishi K., Watatani K., Yoshimatsu T., Masuyama N., Nakajima K., Okano H., Guillemot F., Alessi DR., Gotoh Y.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 106(31)
  
  Pages: 13064-13069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Cell types to order : Temporal specification of CNS stem cells.2009
- Author(s)
  Okano H., Temple S.
- Journal Title
  
  Current Opinion in Neurobiology 19
  
  Pages: 112-119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Musashi1 as a marker of reactive astrocytes after transient focal brain ischemia.2009
- Author(s)
  Oki K, Kaneko N, Kanki H Sa wamoto K, Okano H.
- Journal Title
  
  Neurosci. Res. 66(4)
  
  Pages: 390-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Musashi-1, an RNA-binding protein, is indispensable for survival of photoreceptors.2009
- Author(s)
  Susaki K, Kaneko J, Yamano Y, Nakamura K, In ami W, Yoshikawa T, Ozawa Y, Shibata S, Matsuzaki O, Okano H, Chiba C
- Journal Title
  
  Experimental eye research 88
  
  Pages: 47-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development.2009
- Author(s)
  Saiga T., Fukuda T., Matsumoto M., Tada H., Okano HJ., Okano H., Nakayama KI.
- Journal Title
  
  Mol.Cell Biol. 29(13)
  
  Pages: 3529-3543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Cyclic alopecia caused by the disruption of Sox21- mediated hair shaft cuticle differentiation.2009
- Author(s)
  Kiso M., Tanaka S., Saba R., Matsuda S., Shimizu A., Ohyama M., James-Okano H., Shiroishi T., Okano H., Saga Y.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 106(23)
  
  Pages: 9292-9297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] In vivo imaging in humanized mice2008
- Author(s)
  Masuda H., Okano HJ., Maruya ma T., Yoshimura Y., Okano H., Matsuzaki Y
- Journal Title
  
  Curr Top Microbiol Immunol 324
  
  Pages: 179-196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Hzf regulates adipogenesis through translational control of C/EBPa2008
- Author(s)
  Kawagishi H., Wakoh T., Uno H Maruyama M., Moriya A., Morikawa S., Okano H., Sherr C J., Takagi M., Sugimoto M.
- Journal Title
  
  EMBO J 27
  
  Pages: 1481-1490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Re quirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development.2008
- Author(s)
  Naka H, Nakamura S, Shimazaki T, Okano H
- Journal Title
  
  Nature neuroscience 11
  
  Pages: 1014-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article]2008
- Author(s)
  Kawahara H, Yano M, Imai T, Akamatsu W, Okano HJ, Okano H, Kawahara H, Yano M, Imai T, Akamatsu W, Okano HJ, Okano H
- Journal Title
  
  Kerala, India
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Spatio-temporal recapitulation of central nervous system development by ES cell-derived neural stem/progenitor cells2008
- Author(s)
  Okada Y., Matsumoto A., Shimazaki T., Enoki R., Koizumi A., Ishii S., Itoyama Y., Sobue G., Okano H.
- Journal Title
  
  Stem Cells 26
  
  Pages: 3086-3098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Stage/Cell cycle phase specific nestin gene expression coordinated with the morphological alteration of embryonic cortical neural progenitor cells2008
- Author(s)
  Sunabori T., Tokunaga A., Nagai T., Sawamoto K., Okabe M., Miyawaki A., Matsuzaki Y., Miyata T., Okano H
- Journal Title
  
  J. Cell Sci 121
  
  Pages: 1204-1212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Hzf regulates adipogenesis through translational control of C/EBPalpha.2008
- Author(s)
  Kawagishi H, Wakoh T, Uno H, Maruyama M, Mo riya A, Morikawa S, Okano H, Sherr CJ, Takagi M, Sugimoto M
- Journal Title
  
  The EMBO journal 27
  
  Pages: 1481-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] e ural RNA-binding protein Musashi1 Inhibits Translation Initiation by Competing with eIF4G for PABP.2008
- Author(s)
  Kawahara H, Imai T, Imataka H, Okano H.
- Journal Title
  
  J. Cell Biol. 181
  
  Pages: 639-653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Requirement for COUP-TFI and II in the temporal specification of neura I stem cells in central nervous system development2008
- Author(s)
  Naka H., Nakamura S., Shimazaki T., Okano H.
- Journal Title
  
  Nature Neurosci 11(9)
  
  Pages: 1014-1023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Impaired Motor Functions in Mice Lacking the RNA-binding Protein Hzf.2007
- Author(s)
  Iijima T, Ogura H, Takatsuki K, Shigenori Ka wahara S, Wakabayashi K, Nakayama D, Fujioka M, Kimura Y, Bernstein A, Okano HJ, Kirino Y, Okano H.
- Journal Title
  
  Neurosci Res 58
  
  Pages: 183-189
- NAID
  10024415208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Musashi-1 expression in postnatal mouse olfactory epithelium.2007
- Author(s)
  Watanabe K, Kondo K, Takeuchi N, Okano H, Yam asoba T
- Journal Title
  
  Neuroreort 18
  
  Pages: 641-644
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Coordinated Expression of HuD and GAP-43 in Hippocampal Dentate Granule Cells During Developmental and Adult Plasticity.2007
- Author(s)
  Bolognani F, Tanner DC, Nixon S, Okano HJ, Okano H, Perrone-Bizzozero NI.
- Journal Title
  
  eurochem Res. 32
  
  Pages: 2142-2151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Expression of neural RNA binding protein, Musashi1 in pediatric brain tumors.2007
- Author(s)
  Nakano A, Kanemura Y, Mori K, Kodama E, Ya mamoto A, Sakamoto H, Nakamura Y, Okano H, Yamasaki M, Arita N.
- Journal Title
  
  Pediatric Neurosurgery 43
  
  Pages: 279-283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells.2006
- Author(s)
  Sakaguchi M, Shingo T, S himazaki T, Okano HJ, Shiwa M, Ishibashi S, Oguro H, Ninomiya M, Kadoya T, Horie H, Shibuya A, Mizusawa H, Poirier F, Nakauchi H, Sawamoto K, Okano H.
- Journal Title
  
  Proc Natl Acad Sci USA. 103(18)
  
  Pages: 7112-7117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Musashi1 antigen expression in human fetal germinal matrix development.2006
- Author(s)
  Chan C, Moore BE, Cotman CW, Okano H, Tavares R, Hovanesian V, Pinar H, Johanson CE, Svendsen CN, Stopa EG
- Journal Title
  
  Exp Neurol. 201
  
  Pages: 515-518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] RNA-binding protein HuD regulates neuronal cell identity and maturation2005
- Author(s)
  Akamatsu W, Fujihara H, Mitsuhashi T, Yano M, Shibata S, Hayakawa Y, Okano HJ, Sakakibara S, Takano H, Takano T, Takahashi T, Noda T, Okano H.
- Journal Title
  
  Proc Natl Acad Sci USA. 102
  
  Pages: 4625-4630
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500206
[Journal Article] A novel marker for Purkinje cells, KIAA0864 protein. An analysis based on a monoclonal antibody HFB-16 in developing human cerebellum.2005
- Author(s)
  Nakamura Y, Yamamoto M, Oda E, Kanemura Y, Kodama E, Yamamoto A, Yamamoto H, Miyado K, Okano HJ, Fukagawa R, Higaki K, Yamasaki M, Okano H
- Journal Title
  
  J Histochem Cytochem. 53
  
  Pages: 423-430
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500206
[Journal Article] Nedd9 protein, a Cas-L homologue, is upregulated after transient global ischemia in Rats.2005
- Author(s)
  Sasaki T, Iwata S, Okano HJ, Urasaki Y, Hamada J, Tanaka H, Dang NH, Okano H, Morimoto C.
- Journal Title
  
  Stroke. 36
  
  Pages: 2457-2462
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500206
[Journal Article] Involvement of Hu and hnRNP K in neuronal differentiation through p21 mRNA post-transcriptional regulation2005
- Author(s)
  Yano M, Okano HJ, Okano H.
- Journal Title
  
  J Biol Chem 280
  
  Pages: 12690-12699
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500206
[Journal Article] Hzf Protein Regulates Dendritic Localization and BDNF-induced Translation of Type1 inositol 1,4,5-Trisphosphate Receptor mRNA2005
- Author(s)
  Iijima T, Imai T, Kimura Y, Bernstein A, Okano HJ, Yuzaki M, Okano H.
- Journal Title
  
  Proc Natl Acad Sci USA. 102
  
  Pages: 17190-17195
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500206
[Journal Article] Function of RNA-binding protein Musashi-1 in stem cells.2005
- Author(s)
  Okano H, Kawahara H, Toriya M, Nakao K, Shibata S, Imai T
- Journal Title
  
  Experimental cell research 306
  
  Pages: 349-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Involvement of Hu and heterogeneous nuclear ribonucleoprotein K in neuronal differentiation through p21 mRNA post-transcriptional regulation.2005
- Author(s)
  Yano M, Okano HJ, Oka no H
- Journal Title
  
  The Journal of biological chemistry 280
  
  Pages: 12690-12699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] In vivo imaging of engrafted neural stem cells : its application in evaluating the optimal timing of transplantation for spinal cord injury.2005
- Author(s)
  Okada S, Ishii K, Yamane J, Iwanami A, Ikegami T, Kato H, Iwamoto Y, Nakamura M, Miyoshi H, Okano HJ, Contag CH, Toyama Y, Okano H.
- Journal Title
  
  FASEB J. 19
  
  Pages: 1839-1841
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500206
[Journal Article] The RNA-binding protein HuD regulates neuronal cell identity and maturation.2005
- Author(s)
  Akamatsu W, Fujihara H, Mitsuhashi T, Yano M, Shibata S, Hayakawa Y, Okano HJ, Sakakibara S, Takano H, Takano T, Takahashi T, Noda T, Okano H
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America 102
  
  Pages: 4625-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Journal Article] Hzf protein regulates dendritic localization and BDNF-induced translation of type 1 inositol 1, 4, 5-trisphosphate receptor mRNA.2005
- Author(s)
  Iijima T, Imai T, Kimura Y, Bernstein A, Okano HJ, Yuzaki M, Okano H
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America 102
  
  Pages: 17190-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17024051
[Patent] Methods for Producing Inner Ear Stria Vascularis Marginal Cells, Methods for Evaluating Drugs, and Cell Cultures for Drug Evaluation2022
- Inventor(s)
  三枝智香, 藤岡正人, 岡野栄之
- Industrial Property Rights Holder
  三枝智香, 藤岡正人, 岡野栄之
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-21H04839
[Patent] 内耳前駆細胞の製造方法、内耳有毛細胞の製造方法、薬剤の評価方法、及び内耳細胞分化誘導用組成物2021
- Inventor(s)
  佐伯翼、藤岡正人、細谷誠、岡野栄之、松崎佐栄子
- Industrial Property Rights Holder
  学校法人慶應義塾
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-21H04839
[Patent] 内耳血管条辺縁細胞の製造方法、薬剤の評価方法、及び薬剤評価用細胞培養物2021
- Inventor(s)
  三枝智香、藤岡正人、岡野栄之
- Industrial Property Rights Holder
  学校法人慶應義塾
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-098423
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-21H04839
[Patent] 内耳前駆細胞の製造方法、内耳有毛細胞の製造方法、薬剤の評価方法、及び内耳細胞分化誘導用組成物2021
- Inventor(s)
  佐伯翼、藤岡正人、細谷誠、岡野栄之、松崎佐栄子
- Industrial Property Rights Holder
  学校法人慶應義塾
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-18H04065
[Patent] 内耳有毛細胞の製造方法、薬剤の評価方法、及び細胞分化誘導用組成物2021
- Inventor(s)
  佐伯翼、藤岡正人、細谷誠、岡野栄之、松崎佐栄子
- Industrial Property Rights Holder
  学校法人慶應義塾
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-21H04839
[Patent] 内耳有毛細胞の製造方法、薬剤の評価方法、及び細胞分化誘導用組成物2021
- Inventor(s)
  佐伯翼、藤岡正人、細谷誠、岡野栄之、松崎佐栄子
- Industrial Property Rights Holder
  学校法人慶應義塾
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-18H04065
[Patent] 内耳有毛細胞の製造方法、薬剤の評価方法、及び細胞分化誘導用組成物2020
- Inventor(s)
  佐伯翼、藤岡正人、細谷誠、岡野栄之、松崎佐栄子
- Industrial Property Rights Holder
  学校法人慶應義塾
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-100056
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18H04065
[Patent] 内耳前駆細胞の製造方法、内耳有毛細胞の製造方法、薬剤の評価方法、及び内耳細胞分化誘導用組成物2020
- Inventor(s)
  佐伯翼、藤岡正人、細谷誠、岡野栄之、松崎佐栄子
- Industrial Property Rights Holder
  学校法人慶應義塾
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-100055
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18H04065
[Patent] 音響外傷難聴モデル動物の作製方法及びそれにより作製される音響外傷難聴モデル動物2018
- Inventor(s)
  藤岡正人、岡野洋尚、小島博己、栗原渉、吉田知彦
- Industrial Property Rights Holder
  学校法人慶應義塾、学校法人慈恵大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Acquisition Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-18H04065
[Patent] 音響外傷難聴モデル動物の作製用の音響暴露装置2017
- Inventor(s)
  藤岡正人、岡野洋尚、小島博己、栗原渉、吉田知彦
- Industrial Property Rights Holder
  学校法人慶應義塾、東京慈恵会医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-15H04991
[Patent] 音響外傷難聴モデル動物の作製方法及びそれにより作製される音響外傷難聴モデル動物2017
- Inventor(s)
  藤岡正人、岡野洋尚、小島博己、栗原渉、吉田知彦
- Industrial Property Rights Holder
  学校法人慶應義塾、東京慈恵会医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-15H04991
[Patent] 筋萎縮性側索硬化症および／または前頭側頭葉変性症モデルマウス2013
- Inventor(s)
  岡野栄之　岡野ジェイムス洋尚　宮内央子
- Industrial Property Rights Holder
  岡野栄之　岡野ジェイムス洋尚　宮内央子
- Industrial Property Rights Type
  特許
- Filing Date
  2013-05-30
- Data Source
  KAKENHI-PROJECT-24300122
[Patent] 神経幹細胞の増殖抑制剤2010
- Inventor(s)
  岡野栄之、坂口昌徳、澤本和延、平林淳
- Industrial Property Rights Holder
  学校法人慶應義塾,(独)産業技術総合研究所
- Acquisition Date
  2010-02-16
- Data Source
  KAKENHI-PROJECT-17024051
[Patent] 神経幹細胞の増殖抑制剤2010
- Inventor(s)
  岡野栄之, 他
- Industrial Property Rights Holder
  学校法人慶應義塾、独立行政法人産業技術総合研究所
- Acquisition Date
  2010-02-16
- Data Source
  KAKENHI-PROJECT-17024051
[Patent] AGENT FOR TREATMENT OF NEURAL INJURY ADN METHOD OF THE SAME2008
- Inventor(s)
  (慶應)岡野栄之、中村雅也、辻収彦(共願先), 山中伸弥、三浦恭子
- Industrial Property Rights Holder
  学校法人慶應義塾、国立大学法人京都大学
- Filing Date
  2008-03-07
- Overseas
- Data Source
  KAKENHI-PROJECT-17024051
[Patent] METHOD FOR TREATING THENEURAL INJURY2008
- Inventor(s)
  (慶應)岡野栄之、中村雅也、辻収彦(共願先), 山中伸弥、三浦恭子
- Industrial Property Rights Holder
  学校法人慶應義塾、国立大学法人京都大学
- Filing Date
  2008-02-15
- Overseas
- Data Source
  KAKENHI-PROJECT-17024051
[Patent] 神経損傷治療剤及び神経損傷治療方法2008
- Inventor(s)
  岡野栄之、中村雅也、辻収彦、山中伸弥、三浦恭子
- Industrial Property Rights Holder
  学校法人慶応義塾大学、国立大学法人京都大学
- Filing Date
  2008-06-30
- Overseas
- Data Source
  KAKENHI-PROJECT-17024051
[Patent] 神経損傷治療剤及び神経損傷治療方法2008
- Inventor(s)
  岡野栄之, 他
- Industrial Property Rights Holder
  学校法人慶應義塾、国立大学法人京都大学
- Industrial Property Number
  2008-005844
- Filing Date
  2008-03-07
- Data Source
  KAKENHI-PROJECT-17024051
[Patent] 脊髄損傷治療藥剤2008
- Inventor(s)
  岡野栄之, 他
- Industrial Property Rights Holder
  学校法人慶應義塾、国立大学法人大阪大学、クリングルファーマ株式会社
- Filing Date
  2008-02-08
- Data Source
  KAKENHI-PROJECT-17024051
[Patent] 神経損傷治療剤及び神経損傷治療方法2008
- Inventor(s)
  (慶應)岡野栄之、中村雅也、辻収彦(共願先), 山中伸弥、三浦恭子
- Industrial Property Rights Holder
  学校法人慶應義塾、国立大学法人京都大学
- Industrial Property Number
  2008-058447
- Filing Date
  2008-03-07
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] NIRS を用いた高次脳活動時の脳血液量増加持続時間の解析　－計測システムの構築－2023
- Author(s)
  関根紀夫・白川祟子・古川顕・岡野ジェイムス洋尚・山田惠・松浦勉
- Organizer
  第33回日本保健科学学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08001
[Presentation] 高次脳活動中の高濃度酸素吸入による脳血流変化2023
- Author(s)
  白川崇子、関根紀夫、松浦勉、山﨑奎吾、関根永久、林直弥、岡野ジェイムス洋尚
- Organizer
  第33回日本保健科学学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07723
[Presentation] Functional analysis and regulatory mechanism of shortened splicing isoforms of TDP-43.2023
- Author(s)
  Minami Hasegawa-Ogawa, Asako Onda-Ohto, Arisa Funabashi, Takumasa Nakajo, Ayane Ohya, Hirotaka James Okano
- Organizer
  The 46th Annual Meeting of the Japan Neuroscience Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06812
[Presentation] iPS細胞技術を利用した難治性神経疾患の病態・創薬研究2022
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第１回包括的がん緩和病態生理医療薬学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07302
[Presentation] Analysis of interregional connectivity using MRI images of a common marmoset model of hearing loss2022
- Author(s)
  Motoki Hirabayashi,Sho Kurihara, Junichi Hata,Daisuke Yoshimaru,Masato Fujioka,Yutaka Yamamoto, Hiromi Kojimi,Hirotaka James
- Organizer
  Neuro2022-日本神経科学会
- Data Source
  KAKENHI-PROJECT-21H04839
[Presentation] Analysis of interregional connectivity using MRI images of a common marmoset model of hearing loss2022
- Author(s)
  Motoki Hirabayashi,Sho Kurihara, Junichi Hata,Daisuke Yoshimaru,Masato Fujioka,Yutaka Yamamoto, Hiromi Kojimi,Hirotaka James Okano
- Organizer
  Neuro2022-日本神経科学会
- Data Source
  KAKENHI-PROJECT-22K18399
[Presentation] INDUCED MARGINAL CELLS OF INNER EAR FROM HUMAN IPS CELLS AS THE DISEASE MODELS FOR HEARING LOSS2021
- Author(s)
  Chika Saegusa、Hiroyuki Ozawa、Hideyuki Okano、Masato Fujioka
- Organizer
  ISSCR/JSRM 2021 Tokyo International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04839
[Presentation] iPS細胞技術を利用した疾患モデリングと再生・創薬研究への展開2021
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第74回日本自律神経学会総会
- Data Source
  KAKENHI-PROJECT-21K07302
[Presentation] iPS細胞技術を利用した神経再生戦略と創薬研究2021
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第５９回日本神経眼科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07302
[Presentation] INDUCED MARGINAL CELLS OF INNER EAR FROM HUMAN IPS CELLS AS THE DISEASE MODELS FOR HEARING LOSS2021
- Author(s)
  Chika Saegusa、Hiroyuki Ozawa、Hideyuki Okano、Masato Fujioka
- Organizer
  ISSCR/JSRM 2021 Tokyo International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04065
[Presentation] Selective and super-selective induction of cochlear hair cells from human iPS cells2020
- Author(s)
  Tsubasa Saeki,Makoto Hosoya,Masato Fujioka,Kaoru Ogawa,Hideyuki Okano
- Organizer
  ARO Abstract Confirmation 43rd MidWinter Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04065
[Presentation] Differentiation of human induced pluripotent stem cells into cochlear hair cells2019
- Author(s)
  Tsubasa Saeki,Makoto Hosoya, Masato Fujioka, Kaoru Ogawa, Hideyuki Okano
- Organizer
  NEURO2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04065
[Presentation] 疾患 iPS 細胞でのプロテオミクスが明らかにした Pendred 症候群の新規病態メカニズム2019
- Author(s)
  佐伯翼、細谷誠、芝田晋介、小川郁、藤岡正人、岡野栄之
- Organizer
  第18回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-18H04065
[Presentation] Pathophysiological consequences of Retromer dysfunction in Neurological Disorder2019
- Author(s)
  Hirotaka James Okano
- Organizer
  The 5th International Forum for Lysosomal Storage Diseases
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09766
[Presentation] Pathophysiological studies of familial Parkinson’s Disease PARK17 using iPSC technology2019
- Author(s)
  Hirotaka James Okano
- Organizer
  BRIMS International Neuroscience Symposium 2019 [Neurodegenerative Diseases & Brain Ageing]
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09766
[Presentation] マーモセット蝸牛外らせん溝細胞における細胞間結合の組織学的検討2019
- Author(s)
  佐伯翼、藤岡正人、芝田晋介、細谷誠、小川郁、岡野栄之
- Organizer
  第8回日本マーモセット研究会大会
- Data Source
  KAKENHI-PROJECT-18H04065
[Presentation] Selective induction of cochlear hair cells from human induced pluripotent stem cells2019
- Author(s)
  Tsubasa Saeki,Makoto Hosoya, Masato Fujioka, Kaoru Ogawa, Hideyuki Okano
- Organizer
  56th. Inner Ear Biology Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04065
[Presentation] Cochlear cell modeling using iPSCs unveils a degenerative phenotype and suggests traetments for hereditary hearing loss2018
- Author(s)
  Hosoya M, Fujioka M, Sone T, Okamoto S, Akamatsu W, Ukai H, Ueda HR, Ogawa K, Matsunaga T, Okano H.
- Organizer
  European Academy of Otology and Neurotology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04065
[Presentation] 遺伝性難聴Pendred症候群/DFNB4に対する疾患iPS創薬研究2018
- Author(s)
  藤岡正人、細谷誠、佐伯翼、三枝智香、廣井有香、岡野栄之、小川郁
- Organizer
  第63回日本人類遺伝学大会
- Data Source
  KAKENHI-PROJECT-18H04065
[Presentation] Visualizing the Olfactory Nerve with Ultra-high Field MRI Tractography2018
- Author(s)
  Masayoshi Tei, Sho Kurihara, Eri Mori, Junichi Hata, Hirotaka James Okano, Nobuyoshi Otori, Hiromi Kojima
- Organizer
  27th Congress of the European Rhinologic Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19735
[Presentation] ヒトiPS細胞由来内耳蝸牛外らせん溝細胞におけるPENDRIN相互作用因子の同定2018
- Author(s)
  細谷　誠, 芝田　晋介, 小川　郁,藤岡　正人, 岡野　栄之
- Organizer
  第39回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-18H04065
[Presentation] Topical administration of a gamma-secretase inhibitor LY411575 into the round window niche ameliorates permanent threshold shift in a noise-induced hearing loss model of a non-human primate, the common marmoset2018
- Author(s)
  Masato Fujioka,Tamohiko Yashida ,ShoKurihara, Makoto Koizumi, Makoto Hosaya, Hirotaka James Okano, Hiromi Kojima, Kunio Mizutari, Kaoru Ogawa, Albert Edge
- Organizer
  55th Inner Ear Biology Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04065
[Presentation] Pendred syndrome patient specific iPSCs derived cochlea cells form intracellular PENDRIN aggregation2017
- Author(s)
  佐伯翼・細谷誠・藤岡正人・松永達雄・岡野栄之・小川郁
- Organizer
  第60回日本神経化学大会
- Data Source
  KAKENHI-PROJECT-15H04991
[Presentation] Common Marmoset (Callithrix jacchus): a useful non-human primate model for hearing and audiology research2017
- Author(s)
  Masato Fujioka1, Keigo Hikishima2, Makoto Hosoya1, Noriomi Suzuki1, Takashi Inoue3, Hideyuki Okano4, Hirotaka James Okano5, Kaoru Ogawa
- Organizer
  ENT World Congress IFOS Paris 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04991
[Presentation] Effects of high-energy particles on neural activity in primary cultured cortical neurons2017
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第7回国際放射線神経生物学会大会
- Place of Presentation
  越後湯沢温泉ホテル双葉、新潟
- Year and Date
  2017-02-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15044
[Presentation] ALS/ FTLD model of mutant TDP-43 knock-in mice2015
- Author(s)
  Hirotaka James Okano, Chikako Hara-Miyauchi, Junko Fujigasaki, Shigemi Itohara, Hideyuki Okano
- Organizer
  10th Brain Research Conference “RNA Metabolism in Neurological Disease”.
- Place of Presentation
  The Westin Chicago River North, Chicago, USA
- Year and Date
  2015-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26111723
[Presentation] MYO15A新規遺伝子変異症例からの疾患特異的iPS細胞の樹立と解析2015
- Author(s)
  藤岡正人、細谷　誠・松永　達雄・小川　郁・岡野　栄之
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15H04991
[Presentation] Analysis of axonal degeneration in HuC KO mice2015
- Author(s)
  Yuki Ogawa, Robert Darnell, Hideyuki Okano, Hirotaka James Okano
- Organizer
  10th Brain Research Conference “RNA Metabolism in Neurological Disease”.
- Place of Presentation
  The Westin Chicago River North, Chicago, USA
- Year and Date
  2015-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26111723
[Presentation] PENDRED症候群疾患特異的iPS細胞由来内耳細胞を用いた薬剤スクリーニング2015
- Author(s)
  細谷　誠、藤岡　正人、岡本　理志、曽根　岳史、松永　達雄、赤松　和土、小川　郁、岡野　栄之
- Organizer
  第36回日本炎症・再生医学会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京都港区）
- Year and Date
  2015-07-21
- Data Source
  KAKENHI-PROJECT-15H04991
[Presentation] ヒトES/iPS細胞をソースとした高純度内耳有毛細胞誘導系と人工蝸牛感覚上皮シート作成のこころみ2015
- Author(s)
  藤岡正人、細谷　誠、小川　郁、岡野　栄之
- Organizer
  第36回日本炎症・再生医学会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京都港区）
- Year and Date
  2015-07-21
- Data Source
  KAKENHI-PROJECT-15H04991
[Presentation] Analysis of axonal degenerative mechanisms in HuC KO mice2015
- Author(s)
  Yuki Ogawa, Kyoko Kakumoto, Junji Yamaguchi, Tetsu Yoshida, Robert Darnell, Yasuo Uchiyama, Hideyuki Okano, Hirotaka James Okano
- Organizer
  第38回日本神経科学会大会
- Place of Presentation
  神戸コンベンションセンター（神戸）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PUBLICLY-26111723
[Presentation] Function of Neuronal Elav-like (Hu) Proteins in Embryonic and Adult Brain2013
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第４回新潟大学脳研究所共同研究拠点国際シンポジウム
- Place of Presentation
  新潟大学脳研究所統合脳機能研究センター（新潟）
- Invited
- Data Source
  KAKENHI-PROJECT-24300122
[Presentation] RNA-binding protein HuC is required for maintenance of the axon in Purkinje cells2013
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第３６回日本神経科学大会
- Place of Presentation
  京都国際会議場（京都）
- Data Source
  KAKENHI-PROJECT-24300122
[Presentation] RNA-binding protein HuC is required for maintenance of the axon in Purkinje cells2013
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第３６回日本神経科学大会
- Place of Presentation
  京都国際会議場（京都）
- Data Source
  KAKENHI-PUBLICLY-24111543
[Presentation] Function of Neuronal Elav-like (Hu) Proteins in Embryonic and Adult Brain2013
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第４回新潟大学脳研究所共同研究拠点国際シンポジウム
- Place of Presentation
  新潟大学脳研究所統合脳機能研究センター（新潟）
- Invited
- Data Source
  KAKENHI-PUBLICLY-24111543
[Presentation] HuC is required for maintenance of the axon in cerebellar Purkinje cells2012
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第３５回日本神経科学大会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2012-09-18
- Data Source
  KAKENHI-PUBLICLY-24111543
[Presentation] HuC is required for maintenance of the axon in cerebellar Purkinje cells2012
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-24300122
[Presentation] Fbxo45, a novel ubiquitin ligase, regulates synaptic activity2010
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  BMB2010
- Place of Presentation
  神戸コンベンションセンター、神戸市
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PUBLICLY-21025029
[Presentation] Genetically Modified Non-Human Primate Model of Human Neurodegenerative Diseases2010
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  International Brain Research Organization School Symposium 2010
- Place of Presentation
  Monash University Sunway campus, Malaysia
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PUBLICLY-21025029
[Presentation] 新規ユビキチンリガーゼFbxo45によるシナプス制御2010
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  Neuro2010
- Place of Presentation
  神戸コンベンションセンター、神戸市
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PUBLICLY-21025029
[Presentation] Roles of RNA Binding Protein Hu in Developing and Mature Neurons.2009
- Author(s)
  Hirotaka James Okano
- Organizer
  36th Intemational Congress Of Physiological Sciences (IUPS2009)
- Place of Presentation
  京都国際会議場
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Roles of RN A Binding Protein Hu in Developing and Mature Neurons.2009
- Author(s)
  Okano HJ.
- Organizer
  36th International Congress Of Physiological Sciences (IUPS2009)
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Post-transcriptional regulation of proliferation/differentiation switching in neural stem cells2008
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  34th Annual Meeting of Korean Cancer Association
- Place of Presentation
  Seoul, Korea
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19044038
[Presentation] Strategies for the regeneration of damaged CNS2008
- Author(s)
  Okano H.
- Organizer
  The 17th Biennial Meeting of the International Society for Developmental Neuroscience
- Place of Presentation
  Asilomar, CA, U.S.A.
- Year and Date
  2008-06-03
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Neural differentiation and cell therapy using pluripotent stem cells2008
- Author(s)
  Okano H.
- Organizer
  2nd Symposium on Brain and Mind Research in the Asia / Pacific (BMAP)
- Place of Presentation
  the Matrix, Biopolis, Singapore.
- Year and Date
  2008-09-03
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Neural differentiation and cell therapy using pluripotent stem cells2008
- Author(s)
  Hideyuki Okano
- Organizer
  2^<nd> Symposium on Brain and Mind Research in the Asia / Pacific (BMAP)
- Place of Presentation
  the Matrix, Biopolis, Si ngapore
- Year and Date
  2008-09-03
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Regeneration of the damaged CNS using stem cells2008
- Author(s)
  Okano H.
- Organizer
  Neural Stem Cells & Regenarative Neuroscience Workshop
- Place of Presentation
  Scientia Building, UNSW, Sydney Australia
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Neural differentiation of pluripotent stem cells based therapy for spinal cord injury, the National Centre for Adult Stem Cell Research conference2008
- Author(s)
  H. Okano
- Organizer
  Adult Stem Cells - Biology and Clinical Applications Meeting
- Place of Presentation
  Griffith University, Queensland, Australia
- Year and Date
  2008-11-27
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Neural differentiation of pluripotent stem cells based therapy for spinal cord injury2008
- Author(s)
  Okano H.
- Organizer
  the National Centre for Adult Stem Cell Research conference, Adult Stem Cells - Biology and Clinical Applications Meeting
- Place of Presentation
  Griffith University, Queensland, Australia
- Year and Date
  2008-11-27
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Strategies for the regeneration of damaged CNS2008
- Author(s)
  Hideyuki Okano
- Organizer
  The 17^<th> Biennial Meeting of the International Society for Developmental Neuroscience
- Place of Presentation
  Asilomar, CA, U.S.A.
- Year and Date
  2008-06-03
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Neural differentiation of pluripotent stem cells based therapy for spinal cord injury2008
- Author(s)
  Hideyuki Okano
- Organizer
  the National Centre for Adult Stem Cell Research conference, Adult Stem Cells-Biology and Clinical Applications Meeting
- Place of Presentation
  Griffith University, Que ensland, Australia
- Year and Date
  2008-11-27
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Neural Stem Cells: their involvement in adult neurogenesis and CNS-repair2007
- Author(s)
  Okano, H.
- Organizer
  Stem Cells and CNS Regeneration (Symposium by biosymposia, Inc. )
- Place of Presentation
  Boston, USA.
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Neural Stem Cells: their involvement in adult neurogenesis and CNS-repair2007
- Author(s)
  Okano, H.
- Organizer
  8th World Congress on Inflammation
- Place of Presentation
  Copenhagen, Denmark.
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] A rol of neuronal RNA binding protein Hu and NF45/90 in the nervous system.2007
- Author(s)
  Okano, HJ., Igarashi, M., Yano, M.& Okano, H.
- Organizer
  2007 Annual Meeting of the Society For Nuroscience
- Place of Presentation
  San Diego, USA.
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Molecular Identification of Neural Stem Cell Self-renewing Factor2007
- Author(s)
  Okano, H.
- Organizer
  4th Annual Christopher Reeve "HOT TOPICS" IN STEM CELL BIOLOGY, Satellite Symposium at the 2007 Annual Meeting of the Society For Nuroscience
- Place of Presentation
  San Diego, USA.
- Year and Date
  2007-11-15
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Neural Stem Cells: their involvement in adult neurogenesis and CNS-repair.2007
- Author(s)
  Okano. H.
- Organizer
  8th World Congress on Inflammation
- Place of Presentation
  Copenhagen, Denmark.
- Data Source
  KAKENHI-PROJECT-17024051
[Presentation] Impaired axonal transport in Purkinje cells of HuC knockout mice
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  米国神経科学会
- Place of Presentation
  Walter E Washington Convention Center, Washington D. C. U.S.A.
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-24300122
[Presentation] 小脳プルキンエ細胞におけるHuC依存的軸索輸送機構
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第３７回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24300122
[Presentation] Multimodal and exclusive pathology between ALS and FTLD caused by TDP-43 mutations
- Author(s)
  Hara-Miyauchi C, Date Y, Hasegawa M, Kobayashi R, Fujigasaki J, Kogo N, Sano C, Kobayashi Y, Suzuki N, Itohara S, Okano H, Okano HJ
- Organizer
  米国神経科学会
- Place of Presentation
  Walter E Washington Convention Center, Washington D. C. U.S.A.
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-24300122
[Presentation] Development of biomarkers in peripheral blood cells of ALS model mice.
- Author(s)
  Hasegawa M, Hara-Miyauchi C, Okano HJ
- Organizer
  米国神経科学会
- Place of Presentation
  Walter E Washington Convention Center, Washington D. C. U.S.A.
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-24300122
[Presentation] Impaired axonal transport in Purkinje cells of HuC knockout mice
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  米国神経科学会
- Place of Presentation
  Walter E Washington Convention Center, Washington D. C. U.S.A.
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PUBLICLY-26111723
[Presentation] 小脳プルキンエ細胞におけるHuC依存的軸索輸送機構
- Author(s)
  岡野ジェイムス洋尚
- Organizer
  第３７回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PUBLICLY-26111723

1. OKANO Hideyuki (60160694)

# of Collaborated Projects: 6 results

# of Collaborated Products: 74 results
2. Fujioka Masato (70398626)

# of Collaborated Projects: 5 results

# of Collaborated Products: 37 results
3. Shirakawa Takako (40218045)

# of Collaborated Projects: 4 results

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# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 坊野恵子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
51. 山中修一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 木村実

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 長谷川寿一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 狩野方伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
55. 青木茂樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
56. 長谷川成人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
57. 崎村建司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. 曽根岳史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
59. 山田恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
60. 神崎晶

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
61. 中川真一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okano James Hirotaka 岡野 ジェイムス洋尚

OKANO Hirotaka James 岡野 ジェイムス洋尚

OKANO James Hirotaka 岡野 ジェイムス洋尚

岡野 ジェームス洋尚 オカノ ジェームスヒロタカ

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Regulatory mechanisms of neuronal retromerPrincipal Investigator

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Pathophysiological analysis of Parkinson's Disease using PARK17 patient-derived iPS cellPrincipal Investigator

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Establishment of RNA-based Biomarkers for ALSPrincipal Investigator

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Okano James Hirotaka 岡野ジェイムス洋尚

OKANO Hirotaka James 岡野ジェイムス洋尚

OKANO James Hirotaka 岡野ジェイムス洋尚

岡野ジェームス洋尚オカノジェームスヒロタカ