Fujii Ritsuko 藤井律子

… Alternative Names

FUJII Ritsuko 藤井律子

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Researcher Number	90342716
Other IDs
Affiliation (Current)	2025: 広島文教大学, 人間科学部, 教授
Affiliation (based on the past Project Information) *help	2010 – 2018: 広島文教女子大学, 人間科学部, 教授 2003 – 2004: (財)大阪バイオサイエンス研究所, 神経科学部門, 研究員 2001 – 2002: Osaka Bioscience Institute, Department of Neuroscience, Research Associate, 第3研究部, 研究員
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Functional biochemistry Except Principal Investigator Pathological medical chemistry / Pathological medical chemistry
Keywords	Principal Investigator RNA輸送 / ＲＮＡ代謝 / リン酸化シグナル / RNA代謝 / FUS/TLS / 神経科学 / 脳神経疾患 / シグナル伝達 / TLS/FUS / ALSタイプ６ … More / エクソソーム / ＴＬＳ／ＦＵＳ / ＡＬＳタイプ６ / ＲＮＡ輸送 / ＦＵＳ／ＴＬＳ / リン酸化 / D－セリン / ALS / 精神・神経疾患の病態と治療 / 神経樹状突起 / RNA結合蛋白 … More Except Principal Investigator actin. glutamete / dendritic shine. RNA-binding protein / neuron, neuronal dendrite / Synaptic plasticity / 神経樹状突起 / 大脳新皮質 / mRNA / グルタミン酸シグナル / RNA結合タンパク / 高次脳機能 / グルタミン酸 / RNA結合蛋白 / アクチン / 棘突起 / 樹状突起 / 神経細胞 / シナプス可塑性 / voltage-sensitive dyes / Brain neuron / physiology / neuroscience / membrane potential / ニューロン / 電位感受性色素 / 脳・神経 / 生理学 / 神経科学 / 膜電位 Less

TLS phosphorylation-dependent RNA metabolism in Familial ALS6Principal Investigator
- Principal Investigator
  
  FUJII RITSUKO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Hiroshima Bunkyo Women's University
Molecular basis of aberrant RNA metabolism in familial ALS type6Principal Investigator
- Principal Investigator
  
  Fujii Ritsuko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Hiroshima Bunkyo Women's University
Molecular Pathogenesis of Familial Amyotrophic Lateral SclerosisType 6Principal Investigator
- Principal Investigator
  
  FUJII Ritsuko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Hiroshima Bunkyo Women's University
Functional analysis of an RNA-binding protein, TLS, in neuronal dendrites.
- Principal Investigator
  
  TAKUMI Toru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka Bioscience Institute
大脳皮質ニューロン樹状突起へのRNA結合蛋白によるRNA輸送機構の解明Principal Investigator
- Principal Investigator
  
  藤井律子
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka Bioscience Institute
Measurement and Visualization of membrane potential by genetical manipul ati on.
- Principal Investigator
  
  TAKUMI Toru
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  OSAKA BIOSCIENCE INSTITUTE(OBI)
  Kobe University

All 2018 2015 2014 2012 2011 2010 2004 Other

All Journal Article Presentation Book

[Book] Chapter 9 Animal Models of ALS. Animal models for neurodegenerative disease2011
- Author(s)
  R.Fujii and T. Takumi
- Publisher
  RSC Publishing, Cambridge, UK
- Data Source
  KAKENHI-PROJECT-22500335
[Book] Animal Models for Neurodegenerative Disease RSC Drug Discovery Series No.6 : Chapter 9 Animal Models for ALS2011
- Author(s)
  R.Fujii, T.Takumi
- Total Pages
  37
- Publisher
  The Royal Society of Chemistry (UK)
- Data Source
  KAKENHI-PROJECT-22500335
[Book] Chapter 9 Animal models of ALS.J.Avila, J.J.Lucas and F.Hernandez ed. : Animal models for neurodegenerative disease.ISBN 978-1-84973-275-82011
- Author(s)
  *R.Fujii, T.Takumi *corresponding author
- Publisher
  RSC Publishing (Cambridge, UK)
- Data Source
  KAKENHI-PROJECT-22500335
[Journal Article] Identification of responsible genes and therapeutic targets for ALS.2014
- Author(s)
  Ritsuko Fujii
- Journal Title
  
  Journal of the Society for Food Nutrition
  
  Volume: 32 Pages: 2-6
- Data Source
  KAKENHI-PROJECT-25430080
[Journal Article] RNA binding region of TLS interacts with nucleoporin.2012
- Author(s)
  R.Fujii and T. Takumi
- Journal Title
  
  J. Neurochem.
  
  Volume: 123 (S1) Pages: 60-60
- Data Source
  KAKENHI-PROJECT-22500335
[Journal Article] Expression of NR1 and NR2 splice variants in TLS-deficient mice2012
- Author(s)
  R.Fujii,N. Nishimura and C. Yamamoto:
- Journal Title
  
  J. Neurochem
  
  Volume: 123(S1) Pages: 120-120
- Data Source
  KAKENHI-PROJECT-22500335
[Journal Article] Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain2012
- Author(s)
  B. Rogelj, L.E. Easton, G.K. Bogu, L.W.Stanton, G. Rot, T. Curk, B. Zupan, Y. Sugimoto, M. Modic, N. Haberman, J. Tollervey, R.Fujii, T. Takumi, C E. Shaw and J. Ule
- Journal Title
  
  Sci. Rep
  
  Volume: 2 Issue: 1 Pages: 1-10
- DOI
  10.1038/srep00603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500335
[Journal Article] 精神神経疾患とRNA結合タンパクTLS2010
- Author(s)
  藤井律子
- Journal Title
  
  広島文教食物栄養研究会誌
  
  Volume: 27/28(合併号) Pages: 2-5
- Data Source
  KAKENHI-PROJECT-22500335
[Journal Article] RNA binding protein TLS and neuronal disorders.2010
- Author(s)
  R.Fujii
- Journal Title
  
  Journal of the Society for Food Nutrition
  
  Volume: 27/28 Pages: 2-5
- Data Source
  KAKENHI-PROJECT-22500335
[Journal Article] Domain architectures and characterization of an RNA binding protein, TLS.2004
- Author(s)
  Iko Y, Kodama TS, Kasai N, Oyama T, Morita EH, Muto T, Okumura M, Fujii R, Takumi T, Tate S, Morikawa K
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 44834-44840
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590285
[Journal Article] Domain architectures and characterization of an RNA binding protein, TLS.2004
- Author(s)
  Iko Y, Kodama TS, Kasai N, Oyama T, Morita EH, Muto T, Okumura M, Fujii R, Takumi T, Tate S, Morikawa K
- Journal Title
  
  J. Biol. Chem. 279
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590285
[Journal Article] The RNA binding protein TLS is translocated to the dendritic spines by mGluR5 activation and regulates spine morphogenesis.
- Author(s)
  Fujii R, Okabe S, Urushido T, Inoue K, Yoshimura A, Tachibana T, Nishikawa T, Hicks GG, Takumi T
- Journal Title
  
  Curr.Biol.
- Data Source
  KAKENHI-PROJECT-15590285
[Journal Article] The RNA binding protein TLS is translocated to the dendritic spines by mGluR5 activation and regulates spine morphogenesis.
- Author(s)
  Fujii R, Okabe S, Urashido T, Inoue K, Yoshimura A, Tachibana T, Nishikawa T, Hicks GG, Takumi T
- Journal Title
  
  Curr. Biol.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590285
[Journal Article] The RNA binding protein TLS is translocated to the dendritic spines by mGluR5 activation and regulates spine morphogenesis.
- Author(s)
  Fujii R, Okabe S, Urushido T, Inoue K, Yoshimura A, Tachibana T, Nishikawa T, Hicks GG, Takumi T
- Journal Title
  
  Curr.Biol. (In press.)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590285
[Presentation] Secretion of TLS/FUS-containing RNA exosome is promoted by the Src family tyrosine kinase activation2018
- Author(s)
  Haruka Kasai、Ritsuko Fujii
- Organizer
  15th Meeting of the Asian-Pacific Society for Neurochemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07074
[Presentation] Neuronal depolarization induces tyrosine phosphorylation of TLS/FUS and translocation of TLS/FUS to the nucleus2015
- Author(s)
  N. Shigematsu and R. Fujii
- Organizer
  25th Meeting of the International Society of Neurochemistry
- Place of Presentation
  Cairns, Australia
- Year and Date
  2015-08-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430080
[Presentation] High D-serine content by increased racemase activity in TLS/FUS knockout mice2015
- Author(s)
  R. Araki, Y. Tsukimori, R. Fujii
- Organizer
  25th Meeting of the International Society of Neurochemistry
- Place of Presentation
  Cairns, Australia
- Year and Date
  2015-08-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430080
[Presentation] RNA binding region of TLS interacts with nucleoporin2012
- Author(s)
  R.Fujii
- Organizer
  APSN/the Japanese Society for Neurochemistry
- Place of Presentation
  Kobe,Japan
- Data Source
  KAKENHI-PROJECT-22500335
[Presentation] Expression of NR1 and NR2 splice variants in TLS-deficient mice2012
- Author(s)
  R.Fujii
- Organizer
  APSN/the Japanese Society for Neurochemistry
- Place of Presentation
  Kobe,Japan
- Data Source
  KAKENHI-PROJECT-22500335
[Presentation] Expression of NR1 and NR2 splice variants in TLS-deficient mice.2012
- Author(s)
  R.Fujii,N. Nishimura and C. Yamamoto:
- Organizer
  日本神経化学会
- Data Source
  KAKENHI-PROJECT-22500335
[Presentation] RNA bindingregion of TLS interacts with nucleoporin.2012
- Author(s)
  R.Fujii and T. Takumi
- Organizer
  日本神経化学会
- Data Source
  KAKENHI-PROJECT-22500335
[Presentation] High D-serine content by increased serine racemase activity in TLS/FUS knockout mice
- Author(s)
  Rina Araki, Youmi Tsukimori and Ritsuko Fujii
- Organizer
  25th ISN-13th APSN2015
- Place of Presentation
  Cairns, AU
- Year and Date
  2015-08-23 – 2015-08-27
- Data Source
  KAKENHI-PROJECT-25430080
[Presentation] Neuronal depolarization induces tyrosine phosphorylation of TLS/FUS and translocation of TLS/FUS to the nucleus
- Author(s)
  Naoko Shigematsu and Ritsuko Fujii
- Organizer
  25th ISN-13th APSN2015
- Place of Presentation
  Cairns, AU
- Year and Date
  2015-08-23 – 2015-08-27
- Data Source
  KAKENHI-PROJECT-25430080

1. TAKUMI Toru (00222092)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. MANABE Toshiya (70251212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KURIHARA Tatsuya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Fujii Ritsuko 藤井 律子

FUJII Ritsuko 藤井 律子

Research Projects

Research Products

Co-Researchers

TLS phosphorylation-dependent RNA metabolism in Familial ALS6Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular basis of aberrant RNA metabolism in familial ALS type6Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Pathogenesis of Familial Amyotrophic Lateral SclerosisType 6Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of an RNA-binding protein, TLS, in neuronal dendrites.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

大脳皮質ニューロン樹状突起へのRNA結合蛋白によるRNA輸送機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Measurement and Visualization of membrane potential by genetical manipul ati on.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Chapter 9 Animal Models of ALS. Animal models for neurodegenerative disease2011

Author(s)

Publisher

Data Source

[Book] Animal Models for Neurodegenerative Disease RSC Drug Discovery Series No.6 : Chapter 9 Animal Models for ALS2011

Author(s)

Total Pages

Publisher

Data Source

[Book] Chapter 9 Animal models of ALS.J.Avila, J.J.Lucas and F.Hernandez ed. : Animal models for neurodegenerative disease.ISBN 978-1-84973-275-82011

Author(s)

Publisher

Data Source

[Journal Article] Identification of responsible genes and therapeutic targets for ALS.2014

Author(s)

Journal Title

Data Source

[Journal Article] RNA binding region of TLS interacts with nucleoporin.2012

Author(s)

Journal Title

Data Source

[Journal Article] Expression of NR1 and NR2 splice variants in TLS-deficient mice2012

Author(s)

Journal Title

Data Source

[Journal Article] Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 精神神経疾患とRNA結合タンパクTLS2010

Author(s)

Journal Title

Data Source

[Journal Article] RNA binding protein TLS and neuronal disorders.2010

Author(s)

Journal Title

Data Source

[Journal Article] Domain architectures and characterization of an RNA binding protein, TLS.2004

Fujii Ritsuko 藤井律子

FUJII Ritsuko 藤井律子