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MACHIDE Mitsuru  町出 充

ORCIDConnect your ORCID iD *help
Researcher Number 90346198
External Links
Affiliation (based on the past Project Information) *help 2007: Osaka University, Graduate School of Medicine, Assistant Professor
2002 – 2006: 大阪大学, 医学系研究科, 助手
Review Section/Research Field
Principal Investigator
Pathological medical chemistry
Except Principal Investigator
Biological Sciences / General medical chemistry / Pathological medical chemistry
Keywords
Principal Investigator
c-Met / HGF / aminoacid / oxidant stress / tyrosine phosphatase / cell-cell contact / tissue injury / 発癌 / ストレス / チロシンキナーゼ … More / protein kinase C / juxtamembrane領域 / 組織恒常性 / HGF(肝細胞増殖因子) / アミノ酸 / 酸化ストレス / チロシンフォスファターゼ / 細胞間接着 / 組織傷害 … More
Except Principal Investigator
HGF / c-Met / ノックアウトマウス / チロシンキナーゼ / 分子機構 / 浸潤・転移 / 腫瘍血管新生 / NK4 / Knockout Mouse / Tissue Iniury / Phosohatase / Tissue Regeneration / Signal Transduction / Growth Regulation / 高密度培養 / 細胞増殖制御 / Met / 傷害察知 / フォスファターゼ / 再生 / 細胞内シグナル伝達 / 増殖制御 / knock-out mouse / regenerative medicine / growth factor / liver regeneration / tyrosine kinase / c-Met receptor / tissue regeneration / 恒常性維持 / 細胞内シグナル / 細胞接着 / 肝細胞 / トランスジェニックマウス / 再生医学 / 細胞増殖因子 / 肝再生 / c-Metレセプター / 再生・修復 / 制ガン治療 / 制がん治療 / がん間質 / 制癌戦略 / 癌-間質相互作用 / 細胞骨格 / LIMキナーゼ / クリングルドメイン / 血管新生 / HGFアンタゴニスト / 転移 / 浸潤 / 制癌 / がん悪性化 / 上皮・間葉相互作用 / 筋線維芽細胞 / 線維症 / 血管新生阻害 Less
  • Research Projects

    (6 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (5 People)
  •  がん-間質相互作用のメディエーターとしてのHGF-Met糸の意義とその制御

    • Principal Investigator
      中村 敏一
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Molecular Mechanisms of Tissue Regeneration through the Conversion of HGF Receptor Signaling in Response of Injury

    • Principal Investigator
      NAKAMURA Toshikazu
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka University
  •  がん-間質相互作用のメディエーターとしてのHGF-Met系の意義とその制御

    • Principal Investigator
      中村 敏一
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Molecular Mechanisms for injury-dependent activation of c-Met, HGF receptorPrincipal Investigator

    • Principal Investigator
      MACHIDE Mitsuru
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  Tissue regeneration and homeostasis through functional Met/HGF receptor modification associated with tissue injury.

    • Principal Investigator
      MATSUMOTO Kunio
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  上皮・間葉相互作用によるがん悪性化の分子機構とその制御

    • Principal Investigator
      NAKAMURA Toshikazu
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University

All 2007 2006 2005 2003

All Journal Article Presentation Book

  • [Book] 形質転換成長因子(TGF)、広範囲血液・尿化学検査免疫学的検査(第6版)2005

    • Author(s)
      町出 充, 中村敏一
    • Total Pages
      6
    • Publisher
      日本臨床社(東京)
    • Data Source
      KAKENHI-PROJECT-17014060
  • [Book] 広範囲 血液・尿化学検査、免疫学的検査(4)形質転換成長因子(TGF)α,β2005

    • Author(s)
      町出 充 et al.(分担執筆)
    • Publisher
      日本臨牀社(In press)
    • Data Source
      KAKENHI-PROJECT-15590272
  • [Journal Article] Contact inhibition of hepatocyte growth factor regulated by functional association of the c-Met/HGF receptor and LAR protein tyrosine phosphatase.2006

    • Author(s)
      Machide M. et al.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 8765-8772

    • Data Source
      KAKENHI-PROJECT-18390087
  • [Journal Article] Contact inhibition of hepatocyte growth factor regulated by functional association of the c-Met/HGF receptor and LAR protein tyrosine phosphatase.2006

    • Author(s)
      Machide M. et al.
    • Journal Title

      J. Blol. Chem. 281

      Pages: 8765-8772

    • Data Source
      KAKENHI-PROJECT-18013031
  • [Journal Article] Contact inhibition of hepatocyte growth factor regulated by functional association of the c-Met/HGF receptor and LAR protein tyrosine phosphatase.2006

    • Author(s)
      Machide M. et al.
    • Journal Title

      J Biol Chem (In press)

    • Data Source
      KAKENHI-PROJECT-17014060
  • [Journal Article] Regenerative Therapy by HGF for Liver Disease2003

    • Author(s)
      Machide M. et al.
    • Journal Title

      G.I.Research (Journal of Gastrointestinal Research) Vol.11, No.6

      Pages: 69-76

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590272
  • [Journal Article] 増殖因子の臨床応用 -HGFによる再生医療の展開-2003

    • Author(s)
      町出 充 他
    • Journal Title

      現代医療 35

      Pages: 140-148

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590272
  • [Journal Article] Development of Regenerative Medicine by HGF2003

    • Author(s)
      Machide M. et al.
    • Journal Title

      Gendai-Iryou Vol.35,No.7

      Pages: 140-148

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590272
  • [Journal Article] -HGFによる肝再生医療の展開-2003

    • Author(s)
      町出 充 他
    • Journal Title

      G.I.Research (Journal of Gastrointestinal Research) 11

      Pages: 69-76

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590272
  • [Presentation] Molecular mechanisms of contact inhibition by processing of LAR tyrosine phosphatase2007

    • Author(s)
      Machide, M., et. al.
    • Organizer
      80th Congress of the Japanese Biochemical Society
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-12-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390087
  • [Presentation] LARチロシンホスファターゼのプロセシングを介した細胞密度依存的な肝細胞増殖抑制機構2007

    • Author(s)
      町出 充, ら
    • Organizer
      第80回日本生化学会大会・第30回日本分子生物学会年会合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-11
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390087
  • [Presentation] LARチロシンホスファターゼのプロセシングを介した細胞密度依存的な肝細胞増殖抑制機構2007

    • Author(s)
      町出 充, ら
    • Organizer
      第80回日本生化学会大会・第30回日本分子生物学会年会合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-18013031
  • 1.  NAKAMURA Toshikazu (00049397)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 1 results
  • 2.  MATSUMOTO Kunio (90201780)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  MIZUNO Shinya (10219644)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  KOSHIMIZU Uichi (50281126)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  船越 洋 (40273685)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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