Chono Sumio 丁野純男

… Alternative Names

CHONO Sumio 丁野純男

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Researcher Number	90347790
Other IDs
Affiliation (Current)	2025: 北海道科学大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 北海道科学大学, 薬学部, 教授 2013 – 2017: 北海道薬科大学, 薬学部, 教授 2011: 北海道薬科大学, 薬学部, 教授 2009 – 2010: 北海道薬科大学, 薬学部, 准教授 2008: 北海道薬科大学, 薬学部, 講師 2004 – 2005: 北海道薬科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Medium-sized Section 58:Society medicine, nursing, and related fields / Applied health science / Pharmacology in pharmacy / Physical pharmacy Except Principal Investigator Medical pharmacy / Physical pharmacy
Keywords	Principal Investigator DDS / リポソーム / 駆虫 / アニサキス / 検査・治療 / 肺線維症 / 動脈プラーク / 公衆衛生 / 食文化 / 肺内滞留性 … More / 肺投与 / 生活習慣病 / 可溶化 / ニンテダニブ / 薬物服用習慣 / 肺投与型DDS / 難治性肺疾患 / 抗体修飾リポソーム / 検査 / イメージング / 経気道局所治療 / コラーゲン産生 / 経気道投与型ドラッグデリバリーシステム / bFGF修飾リポソーム / ピルフェニドン / 肺線維芽細胞 / 泡沫細胞 / マクロファージ / 抗LOX1抗体 / マクロファージ及び泡沫細胞 / イムノリポソーム / ドラッグデリバリーシステム(DDS) … More Except Principal Investigator DDS / 肺細胞 / Drug delivery system / Respiratory infection / Alveolar macrophages / Pulmonary administration / Ciprofloxacin / Liposome / ドラッグデリバリーシステム / 呼吸器系感染症 / リポソーム製剤 / 肺胞マクロファージ / 抗生物質 / 呼吸器感染症 / 細胞内寄生菌 / 呼吸器 / 感染症 Less

Pioneering research on development of "Drug Delivery System" for deworming gastrointestinal-infected AnisakisPrincipal Investigator
- Principal Investigator
  
  丁野純男
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Hokkaido University of Science
Discovery of Anisakis anthelmintic components and development of oral formulations that deliver them to AnisakisPrincipal Investigator
- Principal Investigator
  
  CHONO Sumio
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Hokkaido University of Science
Conquest of intractable lung disease due to lifestyle by pulmonary drug delivery systemPrincipal Investigator
- Principal Investigator
  
  CHONO Sumio
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Hokkaido University of Science
  Hokkaido Pharmaceutical University School of Pharmacy
The detection of the artery plaque using the bioimaging and drug delivery systemPrincipal Investigator
- Principal Investigator
  
  Chono Sumio
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied health science
- Research Institution
  Hokkaido Pharmaceutical University School of Pharmacy
New development of pulmonary fibrosis therapy based on pulmonary drug delivery technology with fibrinolysis functionsPrincipal Investigator
- Principal Investigator
  
  Chono Sumio
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Hokkaido Pharmaceutical University School of Pharmacy
Strategy for therapy of atherosclerotic plaque by drug delivery system using immune-liposomesPrincipal Investigator
- Principal Investigator
  
  CHONO Sumio
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Hokkaido Pharmaceutical University School of Pharmacy
Making of treatment system of respiratory infections disease by application of translational mechanisms in lung cells
- Principal Investigator
  
  MORIMOTO Kazuhiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Hokkaido Pharmaceutical University School of Pharmacy
Drug delivery systems by pulmonary administration for treatment of respiratory infections.
- Principal Investigator
  
  MORIMOTO Kazuhiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Hokkaido Pharmaceutical University

[Book] 次世代吸入製剤とデバイスの開発2018
- Author(s)
  丁野純男
- Total Pages
  252
- Publisher
  シーエムシー出版
- ISBN
  9784781313535
- Data Source
  KAKENHI-PROJECT-17H02178
[Journal Article] 北海道産赤ビーツによる便通異常の改善効果についての検討2021
- Author(s)
  85. 千葉健史, 高栗郷, 金田京介, 戸上紘平, 菅原俊継, 相川武司, 秋野利郎, 西村太輔, 山岸丈洋, 丁野純男
- Journal Title
  
  応用薬理
  
  Volume: 100 (5/6) Pages: 95-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22778
[Journal Article] Assessment of transporter-mediated efflux of nintedanib using in vitro cell line models of idiopathic pulmonary fibrosis2020
- Author(s)
  Togami K, Yamaguchi K, Tada H, Chono S
- Journal Title
  
  Die Pharmazie
  
  Volume: 75 Pages: 371-374
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22778
[Journal Article] Prolonged distribution of aerosolized PEGylated liposomes in the lungs of mice with bleomycininduced pulmonary fibrosis2020
- Author(s)
  Togami K, Maruta Y, Nanbu M, Tada H, Chono S
- Journal Title
  
  Drug Dev. Ind. Pharm.
  
  Volume: 46 Issue: 11 Pages: 1873-1880
- DOI
  10.1080/03639045.2020.1825473
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22778, KAKENHI-PROJECT-17H02178, KAKENHI-PROJECT-18K06603, KAKENHI-PROJECT-18K12066
[Journal Article] Three-dimensional imaging of pulmonary fibrotic foci at the alveolar scale using tissueclearing treatment with staining techniques of extracellular matrix2020
- Author(s)
  Togami K, Ozaki H, Yumita Y, Kitayama A, Tada H, Chono S
- Journal Title
  
  Int. J. Biomed. Imaging
  
  Volume: 2020 Pages: 8815231-8815231
- DOI
  10.1155/2020/8815231
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22778, KAKENHI-PROJECT-17H02178, KAKENHI-PROJECT-18K06603, KAKENHI-PROJECT-18K12066
[Journal Article] Assessment of transporter-mediated efflux of nintedanib using in vitro cell line models of idiopathic pulmonary fibrosis2020
- Author(s)
  Togami K, Yamaguchi K, Tada H, Chono S
- Journal Title
  
  Die Pharmazie
  
  Volume: 75 Pages: 371-374
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02178
[Journal Article] Multiscale live imaging using Forster Resonance Energy Transfer (FRET) for evaluating the biological behavior of nanoparticles as drug carriers2020
- Author(s)
  Ishizawa K, Togami K, Tada H, Chono S
- Journal Title
  
  J.Pharm.Sci.
  
  Volume: 109 Issue: 12 Pages: 3608-3616
- DOI
  10.1016/j.xphs.2020.08.028
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22778, KAKENHI-PROJECT-17H02178, KAKENHI-PROJECT-18K06603, KAKENHI-PROJECT-18K12066
[Journal Article] Aerosolized Liposomal Formulation Prevents Enhanced Drug Transfer from Fibrotic Lungs to the Systemic Circulation2020
- Author(s)
  Togami Kohei、Kurasho Kaede、Kanehira Yukimune、Tada Hitoshi、Chono Sumio
- Journal Title
  
  Current Drug Delivery
  
  Volume: 18 Issue: 7 Pages: 923-930
- DOI
  10.2174/1567201818666201229154143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06603, KAKENHI-PROJECT-18K12066, KAKENHI-PROJECT-19K22778
[Journal Article] Evaluation of tissue-clearing techniques for intraorgan imaging of distribution of polymeric nanoparticles as drug carriers2020
- Author(s)
  Ishizawa K, Togami K, Tada H, Chono S
- Journal Title
  
  Drug Dev. Ind. Pharm.
  
  Volume: 46 Issue: 12 Pages: 2061-2069
- DOI
  10.1080/03639045.2020.1843476
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22778, KAKENHI-PROJECT-17H02178, KAKENHI-PROJECT-18K06603, KAKENHI-PROJECT-18K12066
[Journal Article] Evaluation of various tissue-clearing techniques for the three-dimensional visualization of liposome distribution in mouse lungs at the alveolar scale2019
- Author(s)
  Kohei Togami, Takayuki Daisho, Yuki Yumita, Anri Kitayama, Hitoshi Tada, Sumio Chono
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 562 Pages: 218-227
- DOI
  10.1016/j.ijpharm.2019.03.032
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06603, KAKENHI-PROJECT-18K12066, KAKENHI-PROJECT-19K22778, KAKENHI-PROJECT-17H02178
[Journal Article] Intratumoral delivery and therapeutic efficacy of nanoparticle-encapsulated anti-tumor siRNA following intrapulmonary administration for potential treatment of lung cancer2019
- Author(s)
  Kanehira Yukimune、Togami Kohei、Ishizawa Kiyomi、Sato Shingo、Tada Hitoshi、Chono Sumio
- Journal Title
  
  Pharmaceutical Development and Technology
  
  Volume: 24 Issue: 9 Pages: 1095-1103
- DOI
  10.1080/10837450.2019.1633345
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06603, KAKENHI-PROJECT-18K12066, KAKENHI-PROJECT-19K22778, KAKENHI-PROJECT-17H02178
[Journal Article] Conditional examinations for pulverization of lansoprazole orally disintegrating tablets2019
- Author(s)
  Chono S, Nakamura K, Matsui M
- Journal Title
  
  J. Generic Med.
  
  Volume: 15(3) Issue: 3 Pages: 99-103
- DOI
  10.1177/1741134319827064
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22778, KAKENHI-PROJECT-17H02178
[Journal Article] Facile and sensitive HPLC-UV method for determination of nintedanib in rat plasma2018
- Author(s)
  Togami K, Fukuda K, Yamaguchi K, Chono S, Tada H
- Journal Title
  
  Int. J. Pharm. Pharm. Sci.
  
  Volume: 10 Issue: 6 Pages: 133-137
- DOI
  10.22159/ijpps.2018v10i6.25504
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02178
[Journal Article] Tissue-Clearing Techniques Enable Three-Dimensional Visualization of Aerosolized Model Compound and Lung Structure at the Alveolar Scale2018
- Author(s)
  Kohei Togami, Anri Kitayama, Takayuki Daisho, Rui Wang, Hitoshi Tada, Sumio Chono
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 1 Pages: 24-28
- DOI
  10.1248/bpb.b17-00348
- NAID
  130006301224
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19165, KAKENHI-PROJECT-17H02178
[Journal Article] Evaluation of permeability alteration and epithelial-mesenchymal transition induced by transforming growth factor-<beta>1 in A549, NCI-H441, and Calu-3 cells: development of an in vitro model of respiratory epithelial cells in idiopathic pulmonary fibrosis2017
- Author(s)
  Kohei Togami, Kotaro Yamaguchi, Sumio Chono, Hitoshi Tada
- Journal Title
  
  Journal of Pharmacological and Toxicological Methods
  
  Volume: 86 Pages: 19-27
- DOI
  10.1016/j.vascn.2017.02.023
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19165, KAKENHI-PROJECT-17H02178
[Journal Article] Aerosolized liposomes with dipalmitoyl phosphatidylcholine enhance pulmonary absorption of encapsulated insulin compared with co-administered insulin2017
- Author(s)
  Chono S, Togami K, Itagaki S
- Journal Title
  
  Drug Dev. Ind. Pharm.
  
  Volume: 43 Issue: 11 Pages: 1892-1898
- DOI
  10.1080/03639045.2017.1353521
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02178, KAKENHI-PROJECT-16K13049
[Journal Article] Alteration in intrapulmonary pharmacokinetics of aerosolized model compounds due to disruption of the alveolar epithelial barriers following bleomycin-induced pulmonary fibrosis in rats.2016
- Author(s)
  Kohei Togami, Sumio Chino, Hitoshi Tada
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 105 Issue: 3 Pages: 1327-1334
- DOI
  10.1016/j.xphs.2015.12.010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K19165, KAKENHI-PROJECT-25870654
[Journal Article] Tumor distribution and anti-tumor effect of doxorubicin following intrapulmonary administration to mice with metastatic lung tumor.2016
- Author(s)
  Yukimune Kanehira, Kohei Togami, Hitoshi Tada, Sumio Chino
- Journal Title
  
  Journal of Drug Delivery Science and Technology
  
  Volume: 33 Pages: 143-146
- DOI
  10.1016/j.jddst.2016.04.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19165, KAKENHI-PROJECT-25870654
[Journal Article] Sustained distribution of aerosolized PEGylated liposomes in epithelial lining fluid on alveolus surface2016
- Author(s)
  Kaneko K, Togami K, Yamamoto E, Wang S, Morimoto K, Itagaki S, Chono S
- Journal Title
  
  Drug Deliv. Transl. Res.
  
  Volume: 6 Issue: 5 Pages: 565-571
- DOI
  10.1007/s13346-016-0310-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K13049
[Journal Article] Efficient Delivery to Human Lung Fibroblasts (WI-38) of Pirfenidone Incorporated into Liposomes Modified with Truncated Basic Fibroblast Growth Factor and Its Inhibitory Effect on Collagen Synthesis in Idiopathic Pulmonary Fibrosis2015
- Author(s)
  Kohei Togami, Aki Miyao, Kei Miyakoshi, Yukimune Kanehira, Hitoshi Tada, Sumio Chono
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 38 Issue: 2 Pages: 270-276
- DOI
  10.1248/bpb.b14-00659
- NAID
  130004872262
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24790167, KAKENHI-PROJECT-25870654
[Journal Article] Efficient drug delivery to lung epithelial lining fluid by aerosolization of ciprofloxacin incorporated into PEGylated liposomes for treatment of respiratory infections.2011
- Author(s)
  S. Chono, H. Suzuki, K. Togami, K. Morimoto
- Journal Title
  
  J Drug Dev.Ind.Pharm 37
  
  Pages: 367-372
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Effect of surface-mannose modification on aerosolized liposomal delivery to alveolar macrophages2010
- Author(s)
  Chono S
- Journal Title
  
  Drug Dev.Ind.Pharm. 36
  
  Pages: 102-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Aerosol-based efficient delivery of telithromycin, a ketolide antimicrobial agent, to lung epithelial lining fluid and alveolar macrophages for treatment of respiratory infections.2010
- Author(s)
  K. Togami, S. Chono, T. Seki, K. Morimoto
- Journal Title
  
  J Drug Dev.Ind.Pharm 36(7)
  
  Pages: 861-866
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Intracellular pharmacokinetics of telithromycin, a ketolide antibiotic, in alveolar macrophages.2010
- Author(s)
  K. Togami, S. Chono, T. Seki, K. Morimoto
- Journal Title
  
  J.Pharm.Pharmacol 62
  
  Pages: 71-75
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Effect of surface-mannose modification on aerosolized liposomal delivery to alveolar macrophages.2010
- Author(s)
  S. Chono, K. Kaneko, E. Yamamoto, K. Togami, K.Morimoto
- Journal Title
  
  Drug Dev.Ind.Pharm 36(1)
  
  Pages: 102-107
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] DDS化のサイエンスと薬物治療2010
- Author(s)
  丁野純男, 森本一洋
- Journal Title
  
  道薬誌
  
  Volume: 27 Pages: 5-10
- Data Source
  KAKENHI-PROJECT-22790046
[Journal Article] Effect of surface-mannose modification on aerosolized liposomal delivery to alveolar macrophages.2010
- Author(s)
  S.Chono
- Journal Title
  
  Drug Dev.Ind.Pharm.
  
  Volume: 36(1) Pages: 102-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Distribution characteristics of telithromycin, a novel ketolide antimicrobial agent applied for treatment of respiratory infection, in lung epithelial lining fluid and alveolar macrophages.2009
- Author(s)
  K. Togami, S. Chono, T. Seki, K. Morimoto
- Journal Title
  
  Drug Metab.Pharmacokin 24(5)
  
  Pages: 411-417
- NAID
  130004463090
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Aerosolized liposomes with dipalmitoyl phosphatidylcholine enhance pulmonary insulin delivery2009
- Author(s)
  Chono S
- Journal Title
  
  J.Control.Rel. 137
  
  Pages: 50-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Aerosolized liposomes with dipalmitoyl phosphatidylcholine enhance pulmonary insulin delivery.2009
- Author(s)
  S. Chono, R. Fukuchi, T. Seki, K. Morimoto
- Journal Title
  
  J.Control.Rel 137
  
  Pages: 104-109
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Efficient drug delivery to alveolar macrophages and lung epithelial lining fluid following pulmonary administration of liposomal ciprofloxacin in rats with infectious pneumonia and estimation of its antibacterial effects.2008
- Author(s)
  S. Chono, T. Tanino, T. Seki, K. Morimoto
- Journal Title
  
  Drug Dev.lnd.Pharm 34
  
  Pages: 1090-1096
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Efficient drug targeting to rat alveolar macrophages by pulmonary administration of ciprofloxacin incorporated into mannosylated liposomes for treatment of respiratorv intracellular parasitic infections2008
- Author(s)
  S. Chono
- Journal Title
  
  J. Control. Rel 127
  
  Pages: 50-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Efficient drug targeting to rat alveolar macrophages by pulmonary administration of ciprofloxacin incorporated into mannosylated liposomes for treatment of respiratory intracellular parasitic infections.2008
- Author(s)
  S. Chono, T. Tanino, T. Seki, K. Morimoto
- Journal Title
  
  J.Control.Rel 127
  
  Pages: 50-58
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Efficient drug delivery to alveolar macrophages and lung epithelial lining fluid following pulmonary administration of liposomal ciprofloxacin in rats with infectious pneumonia and estimation of its antibacterial effects2008
- Author(s)
  S. Chono
- Journal Title
  
  Drug Dev. Ind. Pharm. 34
  
  Pages: 1090-1096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] ドラッグデリバリーシステムを利用した各種難治性疾患の新規治療戦略
- Author(s)
  丁野純男
- Journal Title
  
  医薬品相互作用研究
  
  Volume: (印刷中)
- Data Source
  KAKENHI-PROJECT-22790046
[Journal Article] Uptake characteristics of anti-LOX1modified liposomes by macrophages and foam cells
- Author(s)
  Chono S and Morimoto K
- Journal Title
  
  J. Drug Targ.
  
  Volume: (投稿中)
- Data Source
  KAKENHI-PROJECT-22790046
[Journal Article] Efficient drug targeting to atherosclerotic lesions by anti-LOX1modified liposomes
- Author(s)
  Chono S and Morimoto K
- Journal Title
  
  J. Control. Rel.
  
  Volume: (投稿中)
- Data Source
  KAKENHI-PROJECT-22790046
[Journal Article] Influence of particle size on drug delivery to alveolar macrophages by pulmonary administration of ciprofloxacin incorporated into liposomes in rat.
- Author(s)
  S.Chono, T.Tanino, T.Seki, K.Morimoto
- Journal Title
  
  J.Drug Target. (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590117
[Journal Article] 薬剤師が知っておきたいDDS製剤の機能とメカニズム
- Author(s)
  丁野純男
- Journal Title
  
  薬局薬学
  
  Volume: (印刷中)
- Data Source
  KAKENHI-PROJECT-22790046
[Journal Article] Influence of particle size on drug delivery to alveolar macrophages by pulmonary administration of ciprofloxacin incorporated into liposomes in rat.
- Author(s)
  S.Chono, T.Tanino, T.Seki, K.Morimoto
- Journal Title
  
  J.Drug Target. (印刷中)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590117
[Patent] カルバクロールを含有する抗アニサキス組成物2024
- Inventor(s)
  丁野純男; 戸上紘平; 中谷日向子
- Industrial Property Rights Holder
  丁野純男; 戸上紘平; 中谷日向子
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-029093
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-23K17446
[Presentation] 抗線維化薬ニンテダニブのシクロデキストリン包接体化による肺内滞留性および肺線維症治療効果の改善2021
- Author(s)
  戸上紘平，小笠原安理沙，入江沙世，岩田健嗣，山口広太郎，多田均，丁野純男
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-19K22778
[Presentation] アニサキス駆虫効果を有する化合物の探索および虫体内への移行性に関する検討2021
- Author(s)
  中谷日向子, 戸上紘平, 丁野純男
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K22778
[Presentation] FRET現象を応用した肺投与型リポソーム製剤の体内挙動の評価法に関する検討2021
- Author(s)
  安田実央, 戸上紘平, 宮島宏季, 石澤清心, 丁野純男
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K22778
[Presentation] 線維化した腎臓を標的とする線維組織親和性ナノ粒子の構築2021
- Author(s)
  中村祐喜, 戸上紘平, 丁野純男
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K22778
[Presentation] 腫瘍病巣を標的とするナノDDSの体内挙動を精確に評価するための蛍光イメージング技術の最適化2021
- Author(s)
  戸上紘平, 石澤清心, 多田均, 丁野純男
- Organizer
  第37回日本DDS学会
- Data Source
  KAKENHI-PROJECT-19K22778
[Presentation] シクロデキストリン複合体化による抗線維化薬ニンテダニブの肺内動態および肺線維症治療効果の改善2020
- Author(s)
  戸上紘平, 岩田健嗣, 小笠原安理沙, 入江沙世, 山口広太郞, 多田均, 丁野純男
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-19K22778
[Presentation] シクロデキストリン複合体化による抗線維化薬ニンテダニブの肺内動態および肺線維症治療効果の改善2020
- Author(s)
  戸上紘平, 岩田健嗣, 小笠原安理沙, 入江沙世, 山口広太郞, 多田均, 丁野純男
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] 抗線維化薬ニンテダニブ-シクロデキストリン複合体の肺投与による肺内動態および肺線維症治療効果の改善2020
- Author(s)
  戸上紘平，小笠原安理沙，入江沙世，岩田健嗣，山口広太郎，多田均，丁野純男
- Organizer
  第36回日本DDS学会
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] 抗線維化薬ニンテダニブ-シクロデキストリン複合体の肺投与による肺内動態および肺線維症治療効果の改善2020
- Author(s)
  戸上紘平，小笠原安理沙，入江沙世，岩田健嗣，山口広太郎，多田均，丁野純男
- Organizer
  第36回日本DDS学会
- Data Source
  KAKENHI-PROJECT-19K22778
[Presentation] Efficient delivery to fibrotic regions of liposomes modified with fibroblast- and collagen-targeting peptides for the treatment of idiopathic pulmonary fibrosis2019
- Author(s)
  Togami K, Hirotsugu Ishii, Ryota Abe, Tada H, Chono S
- Organizer
  Controlled Release Society 2019 Annual Meeting & Exposition, Valencia, Spain
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] Multiscale live-imaging using Forster resonance energy transfer to evaluate the distribution of nanoparticles for drug delivery2019
- Author(s)
  Ishizawa K, Togami K, Tada H, Chono S
- Organizer
  Controlled Release Society 2019 Annual Meeting & Exposition, Valencia, Spain（
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] ヒドロキシプロピル-γ-シクロデキストリンを用いた抗線維化薬ニンテダニブ肺投与の有用性2019
- Author(s)
  戸上紘平, 小笠原安理沙, 入江沙世, 岩田健嗣, 山口広太郎, 多田均, 丁野純男
- Organizer
  日本薬学会第140年会（京都）
- Data Source
  KAKENHI-PROJECT-19K22778
[Presentation] Multiscale live-imaging using Forster resonance energy transfer to evaluate the distribution of nanoparticles for drug delivery2019
- Author(s)
  Ishizawa K, Togami K, Tada H, Chono S
- Organizer
  Controlled Release Society 2019 Annual Meeting & Exposition, Valencia, Spain
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22778
[Presentation] ヒドロキシプロピル-γ-シクロデキストリンを用いた抗線維化薬ニンテダニブ肺投与の有用性2019
- Author(s)
  戸上紘平, 小笠原安理沙, 入江沙世, 岩田健嗣, 山口広太郎, 多田均, 丁野純男
- Organizer
  日本薬学会第140年会（京都）
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] ドラッグデリバリーシステム（DDS）が拓く次世代の創薬・創剤2019
- Author(s)
  丁野純男
- Organizer
  第33回北海道薬物作用談話会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] ドラッグキャリアの体内動態を可視化するreal-time FRET imaging2019
- Author(s)
  石澤清心, 戸上紘平, 多田均, 丁野純男
- Organizer
  第35回日本DDS学会学術集会（横浜）
- Data Source
  KAKENHI-PROJECT-19K22778
[Presentation] Real-time FRET imagingによるドラッグキャリアの体内動態の可視化2019
- Author(s)
  石澤清心, 戸上紘平, 多田均, 丁野純男
- Organizer
  日本薬剤学会第34年会（富山）
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] ドラッグキャリアの体内動態を可視化するreal-time FRET imaging2019
- Author(s)
  石澤清心, 戸上紘平, 多田均, 丁野純男
- Organizer
  第35回日本DDS学会学術集会（横浜）
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] ドラッグデリバリーシステム（DDS）が拓く次世代の創薬・創剤2019
- Author(s)
  丁野純男
- Organizer
  第33回北海道薬物作用談話会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22778
[Presentation] 肺線維症治療を指向したリポソームの肺線維芽細胞への集積性およびcollagen Iへの付着性に関する検討2019
- Author(s)
  戸上紘平, 石井大嗣, 阿部亮太, 多田均, 丁野純男
- Organizer
  日本薬学会第139年会（千葉）
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] 糖尿病、メタボリックシンドロームをターゲットとした機能性表示食品への試み2019
- Author(s)
  若命浩二, 丁野純男, 三原義広, 森澤義人, 河西正文
- Organizer
  第8回日本くすりと糖尿病学会学術集会（札幌）
- Data Source
  KAKENHI-PROJECT-19K22778
[Presentation] Real-time FRET imagingによるドラッグキャリアの体内動態の可視化2019
- Author(s)
  石澤清心, 戸上紘平, 多田均, 丁野純男
- Organizer
  日本薬剤学会第34年会（富山）
- Data Source
  KAKENHI-PROJECT-19K22778
[Presentation] Efficient delivery to fibrotic regions of liposomes modified with fibroblast- and collagen-targeting peptides for the treatment of idiopathic pulmonary fibrosis2019
- Author(s)
  Togami K, Hirotsugu Ishii, Ryota Abe, Tada H, Chono S
- Organizer
  Controlled Release Society 2019 Annual Meeting & Exposition, Valencia, Spain
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22778
[Presentation] ドラッグデリバリーシステムに用いるナノ粒子の体内分布特性評価を目的としたマルチスケールイメージング手法の確立2018
- Author(s)
  石澤清心, 戸上紘平, 多田均, 丁野純男
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] 肺線維症発症時における肺投与型リポソームの肺内滞留性に関する検討2018
- Author(s)
  藏所楓, 兼平幸宗, 多田均, 丁野純男, 戸上紘平
- Organizer
  日本薬学会第145回支部例会（札幌）
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] FRET現象を応用したmulti-scale imagingによるDDSの機能評価法の確立2018
- Author(s)
  石澤清心, 戸上紘平, 多田均, 丁野純男
- Organizer
  日本薬学会第145回支部例会（札幌）
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] Multi-scale imaging using Forster resonance energy transfer for evaluating drug carrier distribution2018
- Author(s)
  Ishizawa K, Togami K, Tada H, Chono S
- Organizer
  2018 AAPS PharmSci 360, Washington DC, USA.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] ドラッグキャリアに用いるナノ粒子と内封薬物の体内分布評価のためのFRET現象を応用したmulti-scale imaging2018
- Author(s)
  石澤清心, 戸上紘平, 多田均, 丁野純男
- Organizer
  第34回日本DDS学会学術集会（長崎）
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] ドラッグデリバリーシステムに用いるナノ粒子の体内分布特性評価を目的としたマルチスケールイメージング手法の確立2018
- Author(s)
  石澤清心, 戸上紘平, 多田均, 丁野純男
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K13049
[Presentation] 肺線維症モデルマウスにおける薬物封入リポソーム肺投与後の肺内滞留性に関する検討2018
- Author(s)
  金澤楓, 戸上紘平, 兼平幸宗, 多田均, 丁野純男
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] 肺線維症の病巣細胞によるニンテダニブの取り込みに及ぼす排出トランスポーターの影響2018
- Author(s)
  山口広太郎, 丁野純男, 多田均, 戸上紘平
- Organizer
  日本薬学会第145回支部例会（札幌）
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] FRET現象を応用したmulti-scale imagingによるドラッグキャリアと内封薬物の体内分布評価法の確立2018
- Author(s)
  石澤清心, 戸上紘平, 多田均, 丁野純男
- Organizer
  日本薬剤学会第33年会（静岡）
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] DPPCリポソームはインスリン未封入体よりも封入体の経肺吸収を優位に促進する2017
- Author(s)
  戸上紘平, 丁野純男
- Organizer
  第33年会日本DDS学会
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] 肺線維症発症時における肺胞閉塞に伴う肺投与型薬物の肺内分布の変化2017
- Author(s)
  戸上紘平, 弓田有輝, 大聖貴之, 王鋭, 多田均, 丁野純男
- Organizer
  日本薬剤学会第32年会
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] Influence of extracellular matrix in fibrotic lesions on the distribution of aerosolized drugs2017
- Author(s)
  Togami K, Yumita Y, Daisho T, Kitayama A, Tada H, Chono S
- Organizer
  Drug Discovery and Therapy World Congress 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02178
[Presentation] 肺線維症発症時における肺胞上皮細胞のタイトジャンクション障害に基づく肺投与型薬物の肺内動態変化2016
- Author(s)
  戸上紘平, 丁野純男, 多田均
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25870654
[Presentation] 薬学の先進的技術～Drug Delivery System～2016
- Author(s)
  丁野純男
- Organizer
  旭川西高校SSH事業・サイエンスハイレベルセミナー
- Place of Presentation
  旭川西高校
- Year and Date
  2016-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-16K13049
[Presentation] くすりの形と生体内運命、そしてドラッグデリバリーシステム2016
- Author(s)
  丁野純男
- Organizer
  天使大学・北海道薬科大学連携公開講座
- Place of Presentation
  天使大学
- Year and Date
  2016-09-08
- Invited
- Data Source
  KAKENHI-PROJECT-16K13049
[Presentation] Altered intrapulmonary pharmacokinetics of aerosolized drugs due to the disruption of the alveolar epithelial barrier in animals with bleomycin-induced pulmonary fibrosis2015
- Author(s)
  Togami K, Tada H, Chono S
- Organizer
  2015 AAPS Annual Meeting and Exposition
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2015-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25870654
[Presentation] 転移性肺がんモデルマウスにおける肺投与薬物の肺腫瘍組織への分布特性2015
- Author(s)
  兼平幸宗, 戸上紘平, 多田均, 丁野純男
- Organizer
  第62回北海道薬学大会
- Place of Presentation
  札幌
- Year and Date
  2015-05-17
- Data Source
  KAKENHI-PROJECT-25870654
[Presentation] 肺線維症モデル動物における肺投与した薬物の肺内動態特性2015
- Author(s)
  戸上紘平，多田均，丁野純男
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25870654
[Presentation] クスリの宅急便ドラッグデリバリーシステム2012
- Author(s)
  丁野純男
- Organizer
  第47回氷雪セミナー
- Place of Presentation
  小樽
- Year and Date
  2012-01-07
- Data Source
  KAKENHI-PROJECT-22790046
[Presentation] 肺薬物送達システムのキャリアーとしてのPEG修飾リボソームの有用性2011
- Author(s)
  山本えり、丁野純男、森本一洋
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] リポソームの動脈硬化巣への集積性2011
- Author(s)
  丁野純男, 森本一洋
- Organizer
  第58回北海道薬学大会
- Place of Presentation
  札幌
- Year and Date
  2011-05-22
- Data Source
  KAKENHI-PROJECT-22790046
[Presentation] Distribution mechanisms of macrolide antibiotics in lung epithelial lining fluid and alveolar macrophages for the therapy of respiratory infections2010
- Author(s)
  K.Morimoto, K.Togami, S. Chono
- Organizer
  2010 AAPS Annual Meeting and Exposition
- Place of Presentation
  New Orleans. LA. USA.
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] 呼吸器感染症治療薬であるマクロライド及びケトライド系抗菌薬の肺粘液層及び肺胞マクロファージ分布2010
- Author(s)
  戸上紘平、丁野純男、森本一洋
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] Distribution mechanisms of macrolide antibiotics in lung epithelial lining fluid and alveolar macrophages for the therapy of respiratory infections2010
- Author(s)
  K.Morimoto, K.Togami, S. Chono
- Organizer
  3^<rd> Indo-Japanese international joint symposium on overcoming interactive diseases prevalent in Asian countries
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] 呼吸器感染症の最適化を目的としたマクロライド及びケトライド系抗生物質の肺組織内動態解析2010
- Author(s)
  森本一洋、戸上紘平、丁野純男
- Organizer
  第7回マクロライド研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] 呼吸器感染症治療の適正化を目的としたマクロライド系抗菌薬の肺組織中濃度からみたAUC/MICの評価2010
- Author(s)
  宮崎誠、戸上紘平、丁野純男、森本一洋, 掛見正郎
- Organizer
  第25回薬物動態学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] 各種マクロライド系抗菌薬の肺組織移行特性に関する検討2009
- Author(s)
  戸上紘平、丁野純男、森本一洋
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] ニューキノロン系抗菌薬の肺胞マクロファージ移行特性の検討2009
- Author(s)
  鈴木宏和、戸上紘平、丁野純男、森本一洋
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] 薬物肺投与システムのキャリアーとしての表面修飾リボソームの有用性2009
- Author(s)
  森本一洋、金子圭太、戸上紘平、丁野純男
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] 呼吸器感染症治療の最適化を目的としたマクロライド及びケトライド系抗生物質の肺組織内動態解析2009
- Author(s)
  戸上紘平、丁野純男、森本一洋
- Organizer
  第16回マクロライド新作用研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] フルオロキノロン系抗菌薬の肺表面及び肺胞マクロファージにおける動態特性2009
- Author(s)
  鈴木宏和、戸上紘平、丁野純男、森本一洋
- Organizer
  第24回日本薬物動態学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] Distribution mechanisms of macrolide antibiotics in lung epithelial lining fluid and alveolar macrophages for the therapy of respiratory infections2009
- Author(s)
  K.Morimoto, K.Togami, S. Chono
- Organizer
  2009 AAPS Annual Meeting and Exposition
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] 肺線維症モデル動物における肺投与後の肺内動態に関する検討
- Author(s)
  戸上紘平,多田均,丁野純男
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25870654
[Presentation] 肺線維症の治療を指向した basic fibroblast growth factor (bFGF) 修飾リポソームの肺線維芽細胞への標的指向化に関する研究
- Author(s)
  宮尾亜希,宮腰恵生,戸上紘平,多田均,丁野純男
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25870654
[Presentation] 肺線維症モデル動物における肺投与型薬物の肺内滞留性及び肺胞深部への到達性に関する検討
- Author(s)
  戸上紘平, 丁野純男, 多田均
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25870654
[Presentation] 肺線維症の治療を指向したbasic fibroblast growth factor（bFGF）修飾リポソームの肺線維芽細胞への標的指向化
- Author(s)
  戸上紘平, 宮尾亜希, 宮腰恵生, 多田均, 丁野純男
- Organizer
  第30回日本DDS学会
- Place of Presentation
  東京
- Year and Date
  2014-07-30 – 2014-07-31
- Data Source
  KAKENHI-PROJECT-25870654
[Presentation] 肺線維症モデル動物における肺投与型製剤の肺内動態に関する検討
- Author(s)
  戸上紘平,多田均,丁野純男
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-25870654
[Presentation] Intrapulmonary pharmacokinetics of aerosolized drugs in animals with bleomycin-induced pulmonary fibrosis
- Author(s)
  Togami K, Tada H, Chono S
- Organizer
  19th North American ISSX / 29th JSSX Meeting
- Place of Presentation
  San Francisco
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-25870654

1. TOGAMI KOHEI (20582357)

# of Collaborated Projects: 4 results

# of Collaborated Products: 48 results
2. 板垣史郎 (00360925)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. MORIMOTO Kazuhiro (10113135)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
4. SEKI Toshinobu (60196946)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. ZHAN XIUYAN

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KANEHIRA YUKIMUNE

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ISHIZAWA KIYOMI

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. HACHISU REI

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. INOUE SHINYA

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Chono Sumio 丁野 純男

CHONO Sumio 丁野 純男

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Pioneering research on development of "Drug Delivery System" for deworming gastrointestinal-infected AnisakisPrincipal Investigator

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Discovery of Anisakis anthelmintic components and development of oral formulations that deliver them to AnisakisPrincipal Investigator

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Conquest of intractable lung disease due to lifestyle by pulmonary drug delivery systemPrincipal Investigator

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The detection of the artery plaque using the bioimaging and drug delivery systemPrincipal Investigator

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New development of pulmonary fibrosis therapy based on pulmonary drug delivery technology with fibrinolysis functionsPrincipal Investigator

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Strategy for therapy of atherosclerotic plaque by drug delivery system using immune-liposomesPrincipal Investigator

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Making of treatment system of respiratory infections disease by application of translational mechanisms in lung cells

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Drug delivery systems by pulmonary administration for treatment of respiratory infections.

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[Book] 次世代吸入製剤とデバイスの開発2018

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[Journal Article] 北海道産赤ビーツによる便通異常の改善効果についての検討2021

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[Journal Article] Assessment of transporter-mediated efflux of nintedanib using in vitro cell line models of idiopathic pulmonary fibrosis2020

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[Journal Article] Prolonged distribution of aerosolized PEGylated liposomes in the lungs of mice with bleomycininduced pulmonary fibrosis2020

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[Journal Article] Three-dimensional imaging of pulmonary fibrotic foci at the alveolar scale using tissueclearing treatment with staining techniques of extracellular matrix2020

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[Journal Article] Assessment of transporter-mediated efflux of nintedanib using in vitro cell line models of idiopathic pulmonary fibrosis2020

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Chono Sumio 丁野純男

CHONO Sumio 丁野純男