SHIMA Yoshihito 嶋良仁

… Alternative Names

嶋良仁シマヨシヒト

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Researcher Number	90362706
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 特任教授(常勤)
Affiliation (based on the past Project Information) *help	2012 – 2014: 大阪大学, 医学(系)研究科(研究院), 助教 2005 – 2006: 大阪大学, 医学系研究科, 助手
Review Section/Research Field	Principal Investigator 膠原病・アレルギー・感染症内科学 Except Principal Investigator 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator 生物学的製剤 / tocilizumab / 抗IL-6受容体抗体 / interleukin-6 / サイトカイン / 全身性強皮症 Except Principal Investigator complementary and alternative medicine / gene polymorphism / prevention / allergy … More / フラボノイド / 予防 / 補完代替医 / 遺伝子多型 / 発症予防 / アレルギー Less

The molecular level influence of tocilizumab administration in patients with systemic sclerosisPrincipal Investigator
- Principal Investigator
  
  SHIMA Yoshihito
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Osaka University
Prediction of onset of allergic diseases through analysis of single nucleotide polymorphisms and prevention of onset of allergic diseases by an appropriate intake of flavonoids
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Osaka University

All 2015 2014 2013 2012 2005 Other

All Journal Article Presentation Book

[Book] Systemic Sclerosis: Basic and Translational2015
- Author(s)
  Takehara K, Kuwana M, Fujimoto M, Ihn H, Yamamoto T, Tuchiya N, Kawaguchi Y, Shima Y, Jinnin M, Motegi S, Matsushita T, Asano Y, Hasegawa M, Hamaguchi Y
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-24591444
[Book] Novel Insights into Systemic Sclerosis ManagementNovel Insights into Systemic Sclerosis Management: Management: Therapeutic potentials of IL-6 inhibition for systemic sclerosis.2013
- Author(s)
  Shima Y, Kuwana M
- Total Pages
  10
- Publisher
  Future Medicine
- Data Source
  KAKENHI-PROJECT-24591444
[Book] IL-6 Targeting Strategy for Various Immune-Mediated Diseases other than Rheumatoid Arthritis: An Update Review Chapter 2, "Interleukin-6: Genetics, Clinical Applications and Role in Disease2013
- Author(s)
  Tanaka T, Ogata A, Shima Y, Narazaki M, Kumanogoh A, Kishimoto T
- Total Pages
  49
- Publisher
  Nova Science Publishers Inc.
- Data Source
  KAKENHI-PROJECT-24591444
[Journal Article] Expansion of range of joint motion following treatment of systemic sclerosis with tocilizumab.2014
- Author(s)
  Shima Y, Hosen N, Hirano T, Arimitsu J, Nishida S, Hagihara K, Narazaki M, Ogata A, Tanaka T, Kishimoto T, Kumanogoh A
- Journal Title
  
  Modern Rheumatology
  
  Volume: 未定 Issue: 1 Pages: 134-137
- DOI
  10.3109/14397595.2013.874749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591444
[Journal Article] Tocilizumab for the Treatment of Patients With Refractory Takayasu Arteritis2013
- Author(s)
  Nakaoka Y, Higuchi K, Arita Y, Otsuki M, Yamamoto K, Hashimoto-Kataoka T, Yasui T, Ikeoka K, Ohtani T, Sakata Y, Shima Y, Kumanogoh A, Yamauchi-Takihara K, Tanaka T, Kishimoto T, Komuro I
- Journal Title
  
  Int. Heart J.
  
  Volume: 54 Issue: 6 Pages: 405-411
- DOI
  10.1536/ihj.54.405
- NAID
  130003383361
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591444
[Journal Article] Retention of tocilizumab and anti-tumour necrosis factor drugs in the treatment of rheumatoid arthritis.2013
- Author(s)
  Hishitani Y, Ogata A, Shima Y, Hirano T, Ebina K, Kunugiza Y, Shi K, Narazaki M, Hagihara K, Tomita T, Yoshikawa H, Tanaka T, Kumanogoh A
- Journal Title
  
  Scandinavian Journal of Rheumatology
  
  Volume: 42 Issue: 4 Pages: 253-259
- DOI
  10.3109/03009742.2012.762037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591444, KAKENHI-PROJECT-24791542
[Journal Article] Expansion of range of joint motion following treatment of systemic sclerosis with tocilizumab.2013
- Author(s)
  Shima Y, Hosen N, Hirano T, Arimitsu J, Nishida S, Hagihara K, Narazaki M, Ogata A, Tanaka T, Kishimoto T, Kumanogoh A
- Journal Title
  
  Modern Rheumatology
  
  Volume: In press
- DOI
  10.1007/s10165-013-0855-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591444
[Journal Article] Blockade of interleukin-6 receptor alleviates disease in mouse model of scleroderma2012
- Author(s)
  Kitaba S, Murota H, Terao M, Azukizawa H, Terabe F, Shima Y, Fujimoto M, Tanaka T, Naka T, Kishimoto T, Katayama I
- Journal Title
  
  Am J Pathol
  
  Volume: 180(1) Issue: 1 Pages: 165-176
- DOI
  10.1016/j.ajpath.2011.09.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591276, KAKENHI-PROJECT-22591101, KAKENHI-PROJECT-22791069, KAKENHI-PROJECT-24591444
[Journal Article] All-trans retinoic acid inhibits the development of mesangial proliferative glomerulonephritis in interleukin-6 transgenic mice.2005
- Author(s)
  Shima Y. et al.
- Journal Title
  
  Nephron Exp Nephrol 100
  
  Pages: 54-62
- Data Source
  KAKENHI-PROJECT-17591040
[Presentation] ヒト型化抗IL-6受容体抗体(tocilizumab)の全身性強皮症に対する影響を探索する無作為比較多施設試験2015
- Author(s)
  嶋　良仁
- Organizer
  第18回強皮症研究会議
- Place of Presentation
  東京
- Year and Date
  2015-01-17
- Data Source
  KAKENHI-PROJECT-24591444
[Presentation] 全身性強皮症患者に対するヒト皮膚用Vesmeterによる評価
- Author(s)
  嶋　良仁
- Organizer
  第17回全身性強皮症研究会議
- Place of Presentation
  大正製薬本社2号館
- Data Source
  KAKENHI-PROJECT-24591444
[Presentation] ヒト型化抗IL-6受容体抗体（トシリズマブ）の全身性強皮症に対する影響を探索する無作為比較多施設試験
- Author(s)
  嶋　良仁、桑名正隆、川口鎮司
- Organizer
  第59回日本リウマチ学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-04-23 – 2015-04-25
- Data Source
  KAKENHI-PROJECT-24591444

1. TANAKA Toshio (40273651)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. NAKA Tetsuji (30303936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 藤本穣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIMA Yoshihito 嶋 良仁

嶋 良仁 シマ ヨシヒト

Research Projects

Research Products

Co-Researchers

The molecular level influence of tocilizumab administration in patients with systemic sclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prediction of onset of allergic diseases through analysis of single nucleotide polymorphisms and prevention of onset of allergic diseases by an appropriate intake of flavonoids

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Systemic Sclerosis: Basic and Translational2015

Author(s)

Publisher

Data Source

[Book] Novel Insights into Systemic Sclerosis ManagementNovel Insights into Systemic Sclerosis Management: Management: Therapeutic potentials of IL-6 inhibition for systemic sclerosis.2013

Author(s)

Total Pages

Publisher

Data Source

[Book] IL-6 Targeting Strategy for Various Immune-Mediated Diseases other than Rheumatoid Arthritis: An Update Review Chapter 2, "Interleukin-6: Genetics, Clinical Applications and Role in Disease2013

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Expansion of range of joint motion following treatment of systemic sclerosis with tocilizumab.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tocilizumab for the Treatment of Patients With Refractory Takayasu Arteritis2013

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Retention of tocilizumab and anti-tumour necrosis factor drugs in the treatment of rheumatoid arthritis.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expansion of range of joint motion following treatment of systemic sclerosis with tocilizumab.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Blockade of interleukin-6 receptor alleviates disease in mouse model of scleroderma2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] All-trans retinoic acid inhibits the development of mesangial proliferative glomerulonephritis in interleukin-6 transgenic mice.2005

Author(s)

Journal Title

Data Source

[Presentation] ヒト型化抗IL-6受容体抗体(tocilizumab)の全身性強皮症に対する影響を探索する無作為比較多施設試験2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 全身性強皮症患者に対するヒト皮膚用Vesmeterによる評価

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] ヒト型化抗IL-6受容体抗体（トシリズマブ）の全身性強皮症に対する影響を探索する無作為比較多施設試験

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

SHIMA Yoshihito 嶋良仁

嶋良仁シマヨシヒト