IWATSUBO Kosaku 岩坪耕策

… Alternative Names

IWATSUBO Kousaku

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Researcher Number	90363796
Affiliation (based on the past Project Information) *help	2012: 横浜市立大学, 医学研究科, 客員准教授 2006: Yokohama City University, Graduate School of Medicine, Assistant Professor 2004 – 2005: Yokohama City Univ., Sch. of Medicine, Assistant Professor, 医学部, 助手 2004: 横浜市立大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine Except Principal Investigator Circulatory organs internal medicine / Biological Sciences
Keywords	Principal Investigator cAMP / アポトーシス / 酵素特異的阻害薬 / β遮断薬 / 心不全 / アデニル酸シクラーゼ Except Principal Investigator cAMP / アデニル酸シクラーゼ / 心不全 / heart … More / catecholamine / 心臓 / カテコラミン / 自律神経 / 遺伝子操作 / downregulation / congestive heart failure / autonomic nervous sytem / 交感神経 / ダウンレギュレーション / new drug / heart failure / apoptosis / adenylyl cyclase / autonomic nervous system / ファルマコ分析 / フォルスコリン / 新薬 / アポプトーシス / 循環器高血圧 / サイクリックAMP / 循環器・高血圧 / シグナル伝達 / ドーパミン / 線条体 / ノックアウト / インシュリン / カルシウム / 褐色細胞腫 / ニコチン受容体 / 増殖シグナル / カベオリン Less

Heart failure rescued by an anti-viral drug which inhibits cardiacadenylyl cyclasefor aging society
- Principal Investigator
  
  TSUNEMATSU Takashi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yokohama City University
新規開発アデニル酸シクラーゼ阻害薬による心筋細胞アポトーシス抑制Principal Investigator
- Principal Investigator
  
  岩坪耕策
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yokohama City University
細胞内酵素機能障害としてのパーキンソン病の研究
- Principal Investigator
  
  石川義弘
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
Molecular mechanisms for cardiac regulation by the autonomic nervous system
- Principal Investigator
  
  ISHIKAWA Yoshihiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yokohama City University Graduate School of Medicine
がん細胞の増殖とカベオリン
- Principal Investigator
  
  ISHIKAWA Yoshihiro
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
The molecular mechanisms for sympathetic regulation of cardiac function
- Principal Investigator
  
  ISHIKAWA Yoshihiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yokohama City University

All 2012 2004 2003

All Journal Article

[Journal Article] Pharmacological stimulation of type 5 adenylyl cyclase stabilizes heart rate under both microgravity and hypergravity induced by parabolic flight2012
- Author(s)
  Bai Y,Tsunematsu T, Jiao Q, Ohnuki Y, Mototani Y, Shiozawa K, Jin M, Cai W, Jin HL, Fujita T, Ichikawa Y, Suita K, Kurotani R, Yokoyama U, Sato M, Iwatsubo K, Ishikawa Y, Okumura S
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 119 Pages: 381-189
- NAID
  10031071685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590811
[Journal Article] Prevention of heart failure in mice by an antiviral agent that inhibits type 5 cardiac adenylyl cyclase2012
- Author(s)
  Iwatsubo K, Bravo C, Uechi M, Baljinnyam E, Nakamura T, Umemura S, Lai L, Gao S, Yan L, Zhao X, Park M, Qiu H, Okumura S, Iwatsubo M, Vatner SF, Vatner DE
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590811
[Journal Article] Direct inhibition of type 5 adenylyl cyclase prevents myocardial apoptosis without functional deterioration.2004
- Author(s)
  Iwatsubo K
- Journal Title
  
  The Journal of Biological Chemistry 279
  
  Pages: 40938-40945
- Data Source
  KAKENHI-PROJECT-16022253
[Journal Article] Disruption of type 5 adenylyl cyclase negates the developmental increase in Golf expression in the striatum2004
- Author(s)
  Iwamoto, T., Iwatsubo, K., Okumura, S.et al.
- Journal Title
  
  FEBS Lett 564
  
  Pages: 153-156
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590763
[Journal Article] Direct inhibition of type 5 adenylyl cyclase prevents myocardial apoptosis without functional deterioration2004
- Author(s)
  Iwatsubo, K., Minamisawa, S., Tsunematsu, T.et al.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 40938-40945
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590763
[Journal Article] Direct inhibition of type 5 adenylyl cyclase prevents myocardial apoptosis without functional deterioration.2004
- Author(s)
  Iwatsubo K
- Journal Title
  
  The Journal of Biological Chemistry 279
  
  Pages: 40938-40945
- Data Source
  KAKENHI-PROJECT-15590763
[Journal Article] Direct inhibition of type 5 adenylyl cyclase prevents myocardial apoptosis without functional deterioration.2004
- Author(s)
  Iwatsubo K
- Journal Title
  
  The Journal of Biological Chemistry 279
  
  Pages: 40938-40945
- Data Source
  KAKENHI-PROJECT-16790426
[Journal Article] Direct inhibition of type 5 adenylyl cyclase prevents myocardial apoptosis without functional deterioration.2004
- Author(s)
  Iwatsubo K et al.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 40938-40945
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590763
[Journal Article] Ischemic preconditioning prevents ischemia-induced beta-adrenergic receptor sequestration.2003
- Author(s)
  Iwatsubo K et al.
- Journal Title
  
  J Mol Cell Cardiol 35
  
  Pages: 923-929
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590763
[Journal Article] Ischemic preconditioning prevents ischemia-induced beta-adrenergic receptor sequestration2003
- Author(s)
  Iwatsubo, K., Toya, Y., Fujita, T.et al.
- Journal Title
  
  J Mol Cell Cardiol 35
  
  Pages: 923-929
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590763
[Journal Article] Isoform-specific regulation of adenylyl cyclase; a potential target in future pharmacotherapy2003
- Author(s)
  Iwatsubo, K., Tsunematsu, T., Ishikawa, Y.
- Journal Title
  
  Expert Opinion on Therapeutic Targets 7
  
  Pages: 441-451
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590763
[Journal Article] Motor dysfunction in type 5 adenylyl cyclase-null mice2003
- Author(s)
  Iwamoto, T., Okumura, S., Iwatsubo, K.et al.
- Journal Title
  
  J Biol Chem 278
  
  Pages: 16936-16940
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590763
[Journal Article] Characterization of beta adrenergic receptor sequestration by newly developed whole cell binding assays.2003
- Author(s)
  Iwatsubo K et al.
- Journal Title
  
  J Cardiovase Pharmacol 41
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590763
[Journal Article] Characterization of beta adrenergic receptor sequestration by newly developed whole cell banding assays2003
- Author(s)
  Iwatsubo, K., Tao, Y., Onda, T.et al.
- Journal Title
  
  J Cardiovasc Pharmacol 41
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590763
[Journal Article] Isoform-specific regulation of adenylyl cyclase ; a potential target in future pharmacotherapy.2003
- Author(s)
  Iwatsubo K et al.
- Journal Title
  
  Expert Opinion on Therapeutic Targets 7
  
  Pages: 441-451
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590763

1. ISHIKAWA Yoshihiro (40305470)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
2. MINAMISAWA Susumu (40257332)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
3. TSUNEMATSU Takashi (70347300)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. OKUMURA Satoshi (60233475)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. KUROTANI Reiko (00453043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. EBINA Toshiaki (60336568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SATO Motohiko (40292122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 戸谷義幸 (30237143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 堀英明 (30117759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 岩本彩男 (80336536)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

IWATSUBO Kosaku 岩坪 耕策

IWATSUBO Kousaku

Research Projects

Research Products

Co-Researchers

Heart failure rescued by an anti-viral drug which inhibits cardiacadenylyl cyclasefor aging society

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規開発アデニル酸シクラーゼ阻害薬による心筋細胞アポトーシス抑制Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細胞内酵素機能障害としてのパーキンソン病の研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms for cardiac regulation by the autonomic nervous system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

がん細胞の増殖とカベオリン

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The molecular mechanisms for sympathetic regulation of cardiac function

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Pharmacological stimulation of type 5 adenylyl cyclase stabilizes heart rate under both microgravity and hypergravity induced by parabolic flight2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Prevention of heart failure in mice by an antiviral agent that inhibits type 5 cardiac adenylyl cyclase2012

Author(s)

Journal Title

Data Source

[Journal Article] Direct inhibition of type 5 adenylyl cyclase prevents myocardial apoptosis without functional deterioration.2004

Author(s)

Journal Title

Data Source

[Journal Article] Disruption of type 5 adenylyl cyclase negates the developmental increase in Golf expression in the striatum2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Direct inhibition of type 5 adenylyl cyclase prevents myocardial apoptosis without functional deterioration2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Direct inhibition of type 5 adenylyl cyclase prevents myocardial apoptosis without functional deterioration.2004

Author(s)

Journal Title

Data Source

[Journal Article] Direct inhibition of type 5 adenylyl cyclase prevents myocardial apoptosis without functional deterioration.2004

Author(s)

Journal Title

Data Source

[Journal Article] Direct inhibition of type 5 adenylyl cyclase prevents myocardial apoptosis without functional deterioration.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Ischemic preconditioning prevents ischemia-induced beta-adrenergic receptor sequestration.2003

Author(s)

Journal Title

IWATSUBO Kosaku 岩坪耕策