KIKUCHI KEIJI 菊地慶司

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KIKUCHI Keiji 菊地慶司

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Researcher Number	90372094
Other IDs
Affiliation (based on the past Project Information) *help	2019: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), その他部局等, その他 2018: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), その他部局等, その他(移行) 2017: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), その他部局等, 主任研究員 2016: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), その他部局等, その他(移行) 2011 – 2014: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), その他部局等, その他 2013: 地方独立行政法人神奈川県立病院機構, 神奈川県立がんセンター臨床研究所, 主任研究員 2013: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), がん生物学部, 主任研究員
Review Section/Research Field	Principal Investigator Tumor therapeutics / Surgical dentistry Except Principal Investigator Surgical dentistry
Keywords	Principal Investigator shedding / EphA2 / 分子標的薬耐性 / 分子標的薬 / ErbBファミリー / 細胞外マトリックス / vemurafenib / 細胞接着 / MT1-MMP / 薬剤耐性 … More / 頭頸部がん / 頭頚部癌 / TAp63 / 頭頸部癌 / SIRT1 … More Except Principal Investigator SIRT1発現 / 頭頸部癌 / エピジェネティクス / 頭頸部扁平上皮癌 / 癌抑制遺伝子 / SIRT1 / 脱アセチル化酵素 Less

Cleavage of EphA2 by MT1-MMP and its participation to drug resistancePrincipal Investigator
- Principal Investigator
  
  KIKUCHI KEIJI
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kanagawa Cancer Center Research Institute
Subcellular localization and biological functions of SIRT1 in head and neck squamous cell carcinomaPrincipal Investigator
- Principal Investigator
  
  KIKUCHI Keiji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kanagawa Cancer Center Research Institute
Establishment of predictive equation for the prognosis of oral squamous cell carcinoma patients on the basis of the expression of ING gene family
- Principal Investigator
  
  TAKANO Yasuo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Kanagawa Cancer Center Research Institute

All 2020 2019 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Sensitization of HT29 colorectal cancer cells to vemurafenib in three-dimensional collagen cultures2020
- Author(s)
  Keiji Kikuchi. Daisuke Hoshino
- Journal Title
  
  Cell Biology International
  
  Volume: 44 Issue: 2 Pages: 621-629
- DOI
  10.1002/cbin.11262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07190
[Journal Article] Association of SIRT1 and the tumor-suppressor gene TAp63 expression in head and neck squamous cell carcinoma2015
- Author(s)
  Kikuchi K, Noguchi A, Kasajima R, Miyagi Y, Hoshino D, Koshikawa N, Kubota A, Yokose T, Takano Y.
- Journal Title
  
  Tumor Biology
  
  Volume: in press Issue: 10 Pages: 7865-72
- DOI
  10.1007/s13277-015-3515-y
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24593043, KAKENHI-PROJECT-25861990
[Journal Article] Gene profile analyses of lens tumor, liver and spleen in α-crystallin/SV40 T antigen transgenic mice treated with Juzentaihoto, a Chinese medicine.2014
- Author(s)
  Zheng H, Nakamura T, Noguchi A, Kikuchi K, Ando T, Takano Y.
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 9 Issue: 2 Pages: 547-552
- DOI
  10.3892/mmr.2013.1854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659958, KAKENHI-PROJECT-24593043
[Journal Article] SIRT1 expression is associated with a poor prognosis, whereas DBC1 is associated with favorable outcomes in gastric cancer.2014
- Author(s)
  Noguchi A, Kikuchi K, Zheng H, Takahashi H, Miyagi Y, Aoki I, Takano Y.
- Journal Title
  
  Cancer Med.
  
  Volume: 3 Issue: 6 Pages: 1553-61
- DOI
  10.1002/cam4.310
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24593043, KAKENHI-PROJECT-25861990, KAKENHI-PROJECT-221S0001
[Journal Article] SIRT1 expression is associated with good prognosis for head and neck squamous cell carcinoma patients.2013
- Author(s)
  Noguchi A, Li X, Kubota A, Kikuchi K, Kameda Y, Zheng H, Miyagi Y, Aoki I, Takano Y.
- Journal Title
  
  Oral Surg Oral Med Oral Pathol Oral Radiol
  
  Volume: 115 Issue: 3 Pages: 385-92
- DOI
  10.1016/j.oooo.2012.12.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659958, KAKENHI-PROJECT-24593043, KAKENHI-PROJECT-25861990
[Journal Article] High SIRT1 expression and low DBC1 expression are associated with poor prognosis in colorectal cancer.2013
- Author(s)
  Kikuchi K, Noguchi A, Takahashi H, Zheng H, Kameda Y, Sekiguchi H, Akaike M, Miyagi Y, Takano Y.
- Journal Title
  
  J. Cancer Therapeutics Res.
  
  Volume: 2 Issue: 1 Pages: 1-8
- DOI
  10.7243/2050-120x-2-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24593043
[Journal Article] Pulmonary tumors associated with the JC virus T-antigen in a transgenic mouse model.2013
- Author(s)
  Noguchi A, Kikuchi K, Ohtsu T, Yoshiwara M, Nakamura Y, Miyagi Y, Zheng H, Takano Y.
- Journal Title
  
  Oncology Reports
  
  Volume: 30 Issue: 6 Pages: 2603-2608
- DOI
  10.3892/or.2013.2782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659958, KAKENHI-PROJECT-24593043
[Presentation] 3次元コラーゲン培養系での大腸がん細胞のvemurafenibに対する高感受性2019
- Author(s)
  菊地慶司
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07190
[Presentation] 頭頸部癌細胞におけるヒストン脱アセチル化酵素SIRT1のTAp63遺伝子発現への関与2014
- Author(s)
  菊地　慶司、笠島　理加、高野　康雄
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24593043
[Presentation] SIRT1 high-expression and low expression of SIRT1 inhibitor DBC1 correlates poor prognosis of colon cancer patients2012
- Author(s)
  Kikuchi K, Noguchi A, Takano Y
- Organizer
  癌学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659958
[Presentation] SIRT1 核発現は頭頸部扁平上皮癌の進展・予後のバイオマーカーである2012
- Author(s)
  野口映、菊地慶司、高野康雄
- Organizer
  日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659958
[Presentation] High expression is associated with poorer survival in patients with gastric cancer2012
- Author(s)
  Noguchi A, Kikuchi K, Takano Y
- Organizer
  癌学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659958
[Presentation] SIRT1 overexpression is an independent poor prognostic indicator of colorectal cancer patients2011
- Author(s)
  Kikuchi K, Noguchi A, Takano Y
- Organizer
  癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659958
[Presentation] Subnuclar localization and degradation of ING4 is correlated with tumotigenesis and progression of HNSCC2011
- Author(s)
  Noguchi A, Takano Y, Kikuchi K
- Organizer
  癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659958
[Presentation] SIRT1 high-expression and low expression f SIRT1 inhibitor DBC1 correlates poor prognosis of colon cancer patients.
- Author(s)
  菊地慶司, 野口映, 高野康雄
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24593043
[Presentation] TGF-β阻害剤はin vitroにおいて繊維芽細胞のHGF産生の亢進を介してがん細胞の浸潤を促進する
- Author(s)
  小柳潤、東昌市、菊地慶司、酒井克也、松本邦夫、宮崎香
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24593043
[Presentation] SIRT1の高発現は胃癌における予後不良因子である.
- Author(s)
  3) 野口映, 菊地慶司, 高野康雄
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24593043
[Presentation] 頭頚部癌細胞におけるヒストン脱アセチル化酵素SIRT1の癌化形質への関与
- Author(s)
  菊地慶司, 野口映, 高野康雄
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24593043

1. TAKANO Yasuo (60142022)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
2. NOGUCHI Makoto (50208328)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
3. NOGUCHI Akira (10456395)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
4. KATAYAMA Kayoko (70584374)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 星野大輔 (30571434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

KIKUCHI KEIJI 菊地 慶司

KIKUCHI Keiji 菊地 慶司

Research Projects

Research Products

Co-Researchers

Cleavage of EphA2 by MT1-MMP and its participation to drug resistancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Subcellular localization and biological functions of SIRT1 in head and neck squamous cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of predictive equation for the prognosis of oral squamous cell carcinoma patients on the basis of the expression of ING gene family

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Sensitization of HT29 colorectal cancer cells to vemurafenib in three-dimensional collagen cultures2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association of SIRT1 and the tumor-suppressor gene TAp63 expression in head and neck squamous cell carcinoma2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gene profile analyses of lens tumor, liver and spleen in α-crystallin/SV40 T antigen transgenic mice treated with Juzentaihoto, a Chinese medicine.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] SIRT1 expression is associated with a poor prognosis, whereas DBC1 is associated with favorable outcomes in gastric cancer.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] SIRT1 expression is associated with good prognosis for head and neck squamous cell carcinoma patients.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High SIRT1 expression and low DBC1 expression are associated with poor prognosis in colorectal cancer.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pulmonary tumors associated with the JC virus T-antigen in a transgenic mouse model.2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] 3次元コラーゲン培養系での大腸がん細胞のvemurafenibに対する高感受性2019

Author(s)

Organizer

Data Source

[Presentation] 頭頸部癌細胞におけるヒストン脱アセチル化酵素SIRT1のTAp63遺伝子発現への関与2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] SIRT1 high-expression and low expression of SIRT1 inhibitor DBC1 correlates poor prognosis of colon cancer patients2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] SIRT1 核発現は頭頸部扁平上皮癌の進展・予後のバイオマーカーである2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] High expression is associated with poorer survival in patients with gastric cancer2012

Author(s)

KIKUCHI KEIJI 菊地慶司

KIKUCHI Keiji 菊地慶司