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Takehara Naofumi  竹原 有史

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TAKEHARA Naofumi  竹原 有史

竹原 有史  タケハラ ナオフミ

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Researcher Number 90374793
Affiliation (Current) 2025: 京都府立医科大学, 医学(系)研究科(研究院), 特任准教授
Affiliation (based on the past Project Information) *help 2021: 京都府立医科大学, 医学(系)研究科(研究院), 特任准教授
2018 – 2020: 旭川医科大学, 医学部, 准教授
2013: 旭川医科大学, 医学部, その他
2010 – 2012: 旭川医科大学, 医学部, 特任講師
2005: 旭川医科大学, 大学病院, 医員
Review Section/Research Field
Principal Investigator
Basic Section 59010:Rehabilitation science-related / Regenerative medicine
Except Principal Investigator
Circulatory organs internal medicine / General surgery
Keywords
Principal Investigator
心機能障害 / 骨格筋再生 / exosome / exosome miRNA / サルコペニア誘導心機能不全 / 不全心筋回復障害 / miRNA / オートファジー / 心臓悪液質 / サルコペニア … More / 再生医学 / 国際情報交換 / 血管新生 / 炎症 / 抗酸化 / 細胞移植 / 虚血耐性 / 抗炎症 / 心筋再生 / Ape1 … More
Except Principal Investigator
心臓 / 移植 / 界面活性剤 / 組織工学 / 再細胞化 / 脱細胞 / 神経再生 / 動脈硬化 / 末梢神経再生 / 血管安定化 / 血管成熟化 / 血管新生 / 分子血管病態学 / アデノウイルス / 血管平滑筋細胞 / Microtubule / Caveolin / Caveolae / Vascular Stiffness Less
  • Research Projects

    (5 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (11 People)
  •  Mechanisms of sarcopenia-induced cardiac function alteration and functional improvement via skeletal muscle regeneration in the ischemic heart.Principal Investigator

    • Principal Investigator
      Takehara Naofumi
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Kyoto Prefectural University of Medicine
      Asahikawa Medical College
  •  Whole Heart Engineering with Decellularization and in vivo Incubation

    • Principal Investigator
      GOJO Satoshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  APE1/ref1 gene provides anti-oxidative fate to Sca-1 positive cardiac progenitor cells and promotes cardiac repair via macrophage transition in ischemic environmentPrincipal Investigator

    • Principal Investigator
      TAKEHARA Naofumi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Regenerative medicine
    • Research Institution
      Asahikawa Medical College
  •  Role of neural regenerative factors on vasa vasorum angiogenesis and remodeling of injured vasculature.

    • Principal Investigator
      KAWABE Junichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Asahikawa Medical College
  •  VascularStiffnessに及ぼすmechanicalstressの役割

    • Principal Investigator
      菊池 健次郎
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Asahikawa Medical College

All 2021 2020 2018 2014 2013 2010

All Journal Article Presentation

  • [Journal Article] Sarcopenia-derived exosomal micro-RNA 16-5p disturbs cardio-repair via a pro-apoptotic mechanism in myocardial infarction in mice2021

    • Author(s)
      Hayasaka Taiki、Takehara Naofumi、Aonuma Tatsuya、Kano Kohei、Horiuchi Kiwamu、Nakagawa Naoki、Tanaka Hiroki、Kawabe Jun-ichi、Hasebe Naoyuki
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 19163-19163

    • DOI

      10.1038/s41598-021-98761-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K10737, KAKENHI-PROJECT-19K19824, KAKENHI-PROJECT-21K08021
  • [Presentation] The pro-apoptotic action of exosomal micro-RNA 16-5p disturbs the cardio-repair process after myocardial ischemia-reperfusion in sarcopenia mice,2021

    • Author(s)
      T Hayasaka, N Takehara, N Hasebe et al.
    • Organizer
      第85回日本循環器学会(横浜)
    • Data Source
      KAKENHI-PROJECT-18K10737
  • [Presentation] The pro-apoptotic action of exosomal micro-RNA 16-5p disturbs the cardio-repair process after myocardial ischemia-reperfusion in sarcopenia mice,2020

    • Author(s)
      T Hayasaka, N Takehara, N Hasebe
    • Organizer
      第85回日本循環器学会(横浜)
    • Data Source
      KAKENHI-PROJECT-18K10737
  • [Presentation] Sarcopenia-derived exosomal micro-RNA 16-5p exerts the cardio-repair disturbance via pro-apoptotic mechanism in myocardial infarction of mice,2020

    • Author(s)
      T Hayasaka, N Takehara, N Hasebe
    • Organizer
      欧州心臓病学会(オランダ)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K10737
  • [Presentation] Tail-suspension induced sarcopenia is associated with a cardio-repair malfunction after myocardial infarction in mice2018

    • Author(s)
      早坂太希、竹原有史他
    • Organizer
      第83回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K10737
  • [Presentation] Apurinic/apyrimidinic endonuclease/redox factor-1 gene provides anti-oxidative state to sca-1 positive cardiac progenitor cells and promotes cardiac repair in ischemic environment2014

    • Author(s)
      Tatsuya Aonuma, Naofumi Takehara, Maki Kabara, Kouki Matsuki, Atsushi Yamauchi, Jun-ichi Kawabe and Naoyuki Hasebe
    • Organizer
      ESC congress 2014
    • Year and Date
      2014-08-30
    • Data Source
      KAKENHI-PROJECT-23618002
  • [Presentation] Antioxidant effects of Apurinic/apyrimidinic endonuclease/redox factor-1 in Sca-1 positive cardiac progenitor cells promote cardiac repair via macrophage transition in an ischemic environment2014

    • Author(s)
      Tatsuya Aonuma*, Naofumi Takehara†, Maki Kabara*, Kouki Matsuki*, Atsushi Yamauchi*, Jun-ichi Kawabe† and Naoyuki Hasebe*
    • Organizer
      ヨーロッパ心臓病学会
    • Place of Presentation
      バルセロナ
    • Data Source
      KAKENHI-PROJECT-23618002
  • [Presentation] Multi-potent capillary pericytes can form matured capillary-like structure by themselves2013

    • Author(s)
      M Kabara, J Kawabe, M Matsuki, A Yamauchi, A Asanome, T Aonuma, A Minoshima, N Nkagawa, N Takehara, N Hasebe
    • Organizer
      N Hasebe 日本循環器学会
    • Place of Presentation
      日本(横浜)
    • Data Source
      KAKENHI-PROJECT-22590820
  • [Presentation] Nerve growth factor induces maturation of vasa vasorum neovasculature in injured vascular walls2010

    • Author(s)
      J Kawabe, A Akira, A Yamauchi, N Takehara, N Hasebe
    • Organizer
      日本血管生物医学会学術集会(第18回)Dec1-3
    • Place of Presentation
      大阪、日本
    • Data Source
      KAKENHI-PROJECT-22590820
  • 1.  KAWABE Junichi (10400087)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 5 results
  • 2.  HASEBE Naoyuki (30192272)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  HIRA Yoshiki (70199024)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  OKADA Motoi (80431427)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  MATSUBARA Hiroaki (10239072)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  GOJO Satoshi (90316745)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  KAMI Daisuke (80415588)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YAGI Hiroshi (20327547)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MATOBA Satoaki (10305576)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  菊池 健次郎 (30045455)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  田中 宏樹 (70596155)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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