MIURA KOICHI 三浦光一

… Alternative Names

MIURA Koichi 三浦光一

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Researcher Number	90375238
Other IDs
Affiliation (Current)	2025: 自治医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2023: 自治医科大学, 医学部, 教授 2019 – 2022: 自治医科大学, 医学部, 准教授 2017 – 2018: 自治医科大学, 医学部, 講師 2016: 秋田大学, 医学部, 特任講師 2010 – 2015: 秋田大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related Except Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology / Basic Section 52010:General internal medicine-related
Keywords	Principal Investigator 非アルコール性脂肪性肝炎 / 腸内細菌 / 肝癌 / Toll-like receptor / コリン / バクテリオファージ / NAFLD / ファージ / 脂肪肝 / Toll様受容体 … More / 自然免疫 / プロバイオティクス / ガン幹細胞 / Toll -like receptor / 肝細胞癌 / Toll like receptor / マクロファージ / TLR / NASH / ケモカイン / 炎症性サイトカイン / 肝臓学 … More Except Principal Investigator 大腸菌 / 腸内細菌 / クローン病 / オートファジー / 急性膵炎 / ファージ / バクテリーファージ / NASH / 心血管イベント / NAFLD / 酸化HDL / Keep1 / K-ras / 膵腺房細胞 / メタボローム解析 / プロテオミクス解析 / LMD / 膵腺房細胞癌 / 膵上皮内癌 / 腺房細胞 / 早期診断 / 膵癌 / TNFSF15 / 小腸 / Ruminococcus gnavus / Escherichia coli / ダブルバルーン小腸内視鏡 / 粘膜関連菌 / 小腸細菌叢 / 腸内細菌叢 / 免疫 / 膵臓病学 / 外分泌 / 膵臓 / オート－ファジー / 酵素顆粒 / rab7 / トリプシン / ノックアウトマウス / VAMP7 Less

クローン病由来大腸菌に対するバクテリオファージの新規検査治療法としての基礎的検討
- Principal Investigator
  
  山本博徳
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Jichi Medical University
バクテリオファージを用いた非アルコール性脂肪性肝炎のコリン代謝評価と治療応用Principal Investigator
- Principal Investigator
  
  三浦光一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Jichi Medical University
非アルコール性脂肪性肝炎と心疾患における酸化HDLの役割解明
- Principal Investigator
  
  五家里栄
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Jichi Medical University
analysis of small intestine-specific bacteria in Crohn's disease and an investigation of TNFSF15, a disease-prone gene
- Principal Investigator
  
  Yamamoto Hironori
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Jichi Medical University
The study to detect early-stage pancreatic cancer based on the data from molecular biology about the atrophic acinar cell surrounding carcinoma in situ.
- Principal Investigator
  
  Kanno Atsushi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Jichi Medical University
  Tohoku University
Application for bacterial therapy through Toll-like receptor 4 on cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  Miura Kouichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical University
  Akita University
The molecular mechanism of autophagy participates in the onset and progression of acute pancreatitis
- Principal Investigator
  
  OHNISHI Hirohide
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical University
The role of macrophages in NASH-related HCC and an application for therapyPrincipal Investigator
- Principal Investigator
  
  Kouichi Miura
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Akita University
Identification and functional analysis of SNARE proteins participating in the onset of acute pancreatitis
- Principal Investigator
  
  Ohnishi Hirohide
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Akita University
Innate immunity and non-alcoholic steatohepatitis. A study for developing new immunologic therapy.Principal Investigator
- Principal Investigator
  
  MIURA Koichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Akita University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010

All Journal Article Presentation Book

[Book] The Liver in Systemic Diseases2016
- Author(s)
  Miura K
- Total Pages
  343
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-16K09337
[Book] NASH発症および進展における腸内細菌と肝自然免疫の役割消化器内科2011
- Author(s)
  三浦光一、大西洋英
- Data Source
  KAKENHI-PROJECT-22590714
[Journal Article] Probiotics suppress nonalcoholic steatohepatitis and carcinogenesis progression in hepatocyte-specific PTEN knockout mice2022
- Author(s)
  Arai N, Miura K, Aizawa K, Sekiya M, Nagayama M, Sakamoto H, Maeda H, Morimoto N, Iwamoto S, Yamamoto H.
- Journal Title
  
  Sci Rep
  
  Volume: 12 Issue: 1 Pages: 16206-16206
- DOI
  10.1038/s41598-022-20296-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08016
[Journal Article] Oxidized high-density lipoprotein shows a stepwise increase as fibrosis progresses in patients with nonalcoholic fatty liver disease.2021
- Author(s)
  Miura K, Arai N, Goka R, Morimoto N, Watanabe S, Isoda N, Yamamoto H, Kotani K.
- Journal Title
  
  Antioxidants
  
  Volume: 10 Issue: 2 Pages: 239-239
- DOI
  10.3390/antiox10020239
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07872, KAKENHI-PROJECT-21K07374
[Journal Article] TH1 cell-inducing Escherichia coli strain identified from the small intestinal mucosa of patients with Crohn’s disease2020
- Author(s)
  Nagayama M, Yano T, Atarashi K, Tanoue T, Sekiya M, Kobayashi Y, Sakamoto H, Miura K, Sunada K, Kawaguchi T, Morita S, Sugita K, Narushima S, Barnich N, Isayama J, Kiridooshi Y, Shiota A, Suda W, Hattori M, Yamamoto H, Honda K.
- Journal Title
  
  Gut Microbes
  
  Volume: 12 Issue: 1 Pages: 1788898-1788898
- DOI
  10.1080/19490976.2020.1788898
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08401
[Journal Article] IgG4-related Sclerosing Cholangitis Mimicking Cholangiocarcinoma Diagnosed by Endoscopic Ultrasound-guided Fine-needle Aspiration.2020
- Author(s)
  Matsumoto R, Miura S, Kanno A,et al.
- Journal Title
  
  Intern Med.
  
  Volume: 59 Pages: 945-50
- NAID
  130007825324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07897
[Journal Article] Preoperative biliary drainage of the hepatic lobe to be resected does not affect liver hypertrophy after percutaneous transhepatic portal vein embolization.2019
- Author(s)
  Miura S, Kanno A, et al.
- Journal Title
  
  Surg Endosc.
  
  Volume: 34 Issue: 2 Pages: 667-74
- DOI
  10.1007/s00464-019-06813-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07897
[Journal Article] Pancreatic Acinar Cell Carcinoma with Multiple Liver Metastases Effectively Treated by S-1 Chemotherapy2018
- Author(s)
  Yoshida Naoki、Kanno Atsushi、Masamune Atsushi、Nabeshima Tatsuhide、Hongo Seiji、Miura Shin、Takikawa Tetsuya、Hamada Shin、Kikuta Kazuhiro、Kume Kiyoshi、Ueno Masamichi、Shimosegawa Tooru
- Journal Title
  
  Internal Medicine
  
  Volume: 57 Issue: 24 Pages: 3529-3535
- DOI
  10.2169/internalmedicine.0294-17
- NAID
  130007531150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07897
[Journal Article] Altered composition of gut microbiota and the immune response in experimental steatohepatitis mouse models2017
- Author(s)
  Ishioka M, Miura K, Minami S, Shimura Y, Ohnishi H
- Journal Title
  
  Dig Dis Sci
  
  Volume: 62 Issue: 2 Pages: 396-406
- DOI
  10.1007/s10620-016-4393-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09337
[Journal Article] Disruption of Small GTPase Rab7 Exacerbates the Severity of Acute Pancreatitis in Experimental Mouse Models2017
- Author(s)
  Kenichi Takahashi, Hirosato Mashima, Kouichi Miura, Daichi Maeda, Akiteru Goto, Takashi Goto, Ge-Hong Sun-Wada, Yoh Wada, Hirohide Ohnishi
- Journal Title
  
  Scientific Reports
  
  Volume: 印刷中
- NAID
  120007089052
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K09389
[Journal Article] The Roles of gut microbiota and Toll-like receptors in obesity and nonalcoholic fatty liver disease2017
- Author(s)
  Miura K, Ishioka M, Iijima K
- Journal Title
  
  JOMES
  
  Volume: 26 Pages: 107-113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09337
[Journal Article] TRIF Differentially Regulates Hepatic Steatosis and Inflammation/ Fibrosis in Mice2017
- Author(s)
  Yang L, Miura K, Zhang B, Matsushita H, Yang YM, Liang S, Song J, Roh YS, Seki E.
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 3 Issue: 3 Pages: 469-83
- DOI
  10.1016/j.jcmgh.2016.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09337
[Journal Article] Disruption of Small GTPase Rab7 Exacerbates the Severity of Acute Pancreatitis in Experimental Mouse Models.2017
- Author(s)
  Mouse Models. Takahashi K, Mashima H, Miura K, Maeda D, Goto A, Goto T, Sun-Wada GH, Wada Y, Ohnishi H.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 2817-2817
- DOI
  10.1038/s41598-017-02988-3
- NAID
  120007089052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08646, KAKENHI-PROJECT-16K09337, KAKENHI-PROJECT-16K09401, KAKENHI-PUBLICLY-16H01201
[Journal Article] Toll-like Receptor 4 on Macrophage Promotes the Development of Steatohepatitis-related Hepatocellular Carcinoma in Mice.2016
- Author(s)
  Miura K, Ishioka M, Minami S, Horie Y, Ohshima S, Goto T, Ohnishi H
- Journal Title
  
  J Biol Chem
  
  Volume: 291 Issue: 22 Pages: 11504-11517
- DOI
  10.1074/jbc.m115.709048
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K09337
[Journal Article] Requirement of Gαq/Gα11 Signaling in the Preservation of Mouse Intestinal Epithelial Homeostasis.2016
- Author(s)
  Watanabe N, Mashima H, Miura K, Goto T, Yoshida M, Goto A, Ohnishi H
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology.
  
  Volume: 2 Issue: 6 Pages: 767-782
- DOI
  10.1016/j.jcmgh.2016.08.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K09337
[Journal Article] 腸内細菌と線維化合併肝細胞癌2015
- Author(s)
  三浦光一、石岡充彬、大西洋英
- Journal Title
  
  肝胆膵
  
  Volume: 70 Pages: 883-888
- Data Source
  KAKENHI-PROJECT-25460973
[Journal Article] 腸内細菌と肝癌2014
- Author(s)
  三浦光一、大西洋英
- Journal Title
  
  医学のあゆみ
  
  Volume: 251 Pages: 63-68
- Data Source
  KAKENHI-PROJECT-25460973
[Journal Article] Role of gut microbiota and Toll-like receptors in nonalcoholic fatty liver disease.2014
- Author(s)
  Miura K, Ohnishi H
- Journal Title
  
  World J Gastroenterol
  
  Volume: 20 Issue: 23 Pages: 7381-7391
- DOI
  10.3748/wjg.v20.i23.7381
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460973
[Journal Article] Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice2013
- Author(s)
  Miura K, Yang L, van Rooijen N, Brenner DA, Ohnishi H, Seki E
- Journal Title
  
  Hepatology
  
  Volume: 57 Pages: 577-89
- Data Source
  KAKENHI-PROJECT-22590714
[Journal Article] Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice.2013
- Author(s)
  Miura K
- Journal Title
  
  Hepatology
  
  Volume: 57 Issue: 2 Pages: 577-589
- DOI
  10.1002/hep.26081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590714
[Journal Article] Nonalcoholic fatty liver disease: from lipid profile to treatment2012
- Author(s)
  Miura K and Ohnishi H
- Journal Title
  
  Clin J Gastroenterol
  
  Volume: 5 Pages: 313-21
- Data Source
  KAKENHI-PROJECT-22590714
[Journal Article] Nonalcoholic fatty liver disease: from lipid profile to treatment.2012
- Author(s)
  Miura K
- Journal Title
  
  Clin J Gastroenterol
  
  Volume: 5 Issue: 5 Pages: 313-321
- DOI
  10.1007/s12328-012-0315-4
- Data Source
  KAKENHI-PROJECT-22590714
[Journal Article] Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2.2012
- Author(s)
  Miura K
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol.
  
  Volume: 302 Issue: 11 Pages: G1310-G1321
- DOI
  10.1152/ajpgi.00365.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590714
[Journal Article] Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR22012
- Author(s)
  Miura K, Yang L, van Rooijen N, Ohnishi H, Seki E
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 302
- Data Source
  KAKENHI-PROJECT-22590714
[Journal Article] NASH発症および進展における腸内細菌叢と肝自然免疫の役割2011
- Author(s)
  三浦光一
- Journal Title
  
  消化器内科
  
  Volume: 52巻 Pages: 499-505
- Data Source
  KAKENHI-PROJECT-22590714
[Journal Article] Non-alcoholic steatohepatitis-induced fibrosis: Toll-like receptors, reactive oxygen species and Jun N-terminal kinase2011
- Author(s)
  Brenner DA, Seki E, Taura K, Kisseleva T, Deminicis S, Iwaisako K, Inokuchi S, Schnabl B, Oesterreicher CH, Paik YH, Miura K, Kodama Y
- Journal Title
  
  Hepatol Res
  
  Volume: 41 Pages: 683-6
- Data Source
  KAKENHI-PROJECT-22590714
[Journal Article] Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression2011
- Author(s)
  Osawa Y, Seki E, Kodama Y, Suetsugu A, Miura K, Adachi M, Ito H, Shiratori Y, Banno Y, Olefsky JM, Nagaki M, Moriwaki H, Brenner DA, Seishima M
- Journal Title
  
  FASEB J
  
  Volume: 25 Pages: 1133-44
- Data Source
  KAKENHI-PROJECT-22590714
[Journal Article] Role of toll-like receptors and their downstream molecules in the development of nonalcoholic Fatty liver disease2010
- Author(s)
  Miura K, Seki E, Ohnishi H, Brenner DA
- Journal Title
  
  Gastroenterol Res Pract
  
  Pages: 362847-362847
- Data Source
  KAKENHI-PROJECT-22590714
[Journal Article] Role of toll-like receptors and their downstream molecules in the development of nonalcoholic Fatty liver disease.2010
- Author(s)
  Miura K, et al.
- Journal Title
  
  Gastroenterol Res Pract
  
  Volume: 2010 Pages: 362847-362847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590714
[Journal Article] Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice2010
- Author(s)
  Miura K, Kodama Y, Inokuchi S, Schnabl B, Aoyama T, Ohnishi H, Olefsky JM, Brenner DA, Seki E
- Journal Title
  
  Gastroenterology
  
  Volume: 139(1) Pages: 323-34
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] 肝疾患における腸内細菌と臓器相関　酸化ストレスを介したマウスNASHおよびNASH発癌におけるプロバイオティクスの抑制効果2023
- Author(s)
  三浦光一
- Organizer
  日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22K08016
[Presentation] Effects of probiotics on mice presented with steatohepatitis and liver tumors2023
- Author(s)
  三浦光一
- Organizer
  JSH International Liver Conference 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08016
[Presentation] 消化管出血に対する診療の進歩　Gel immersion endoscopyに最適化したgelの流量と粘度に影響する因子2022
- Author(s)
  矢野　智則, 大畑　淳, 平木勇次, 三浦義正, 坂本博次, 砂田　圭二郎, 山本　博徳
- Organizer
  第18回日本消化管学会総会学術総会
- Data Source
  KAKENHI-PROJECT-19K08401
[Presentation] NAFLD/NASHにおける冠動脈疾患発見のための新しいバイオマーカー酸化HDLの可能性2021
- Author(s)
  三浦光一、荒井道、五家里栄、森本直樹、渡邊俊司、津久井舞未子、野本弘章、佐藤直人、前田浩史、礒田憲夫、山本博徳
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-21K07374
[Presentation] クローン病の小腸細菌叢解析から同定されたクローン病関連大腸菌は腸炎誘導能を有する2020
- Author(s)
  永山学、矢野智則、関谷万理子、坂本博次、三浦光一、砂田圭二郎、河口貴昭、森田覚、本田賢也、山本博徳
- Organizer
  第58回日本小腸学会総会
- Data Source
  KAKENHI-PROJECT-19K08401
[Presentation] 炎症性主膵管狭窄とstage0-I膵癌の臨床像の比較2019
- Author(s)
  三浦晋　菅野敦　ほか
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18K07897
[Presentation] エゼチミブによる非アルコール性脂肪性肝炎からの肝発癌抑制効果2018
- Author(s)
  三浦光一、森本直樹、礒田憲夫
- Organizer
  日本肝臓学会
- Data Source
  KAKENHI-PROJECT-16K09337
[Presentation] 腸内細菌とTLRシグナルからみたNASH進展のメカニズム2018
- Author(s)
  三浦光一、森本直樹、礒田憲夫
- Organizer
  日本肝臓学会
- Data Source
  KAKENHI-PROJECT-16K09337
[Presentation] 腸内細菌はNASHの原因か結果か？ -マウスNASHモデルにおける検討-2018
- Author(s)
  三浦光一、森本直樹、石岡充彬、南慎一郎、礒田憲夫、山本博徳
- Organizer
  肝臓と糖尿病代謝研究会 (日本肝臓学会)
- Invited
- Data Source
  KAKENHI-PROJECT-16K09337
[Presentation] 高コレステロール血症改善によるNASH発癌抑制効果2018
- Author(s)
  三浦光一、森本直樹、礒田憲夫
- Organizer
  日本肝臓学会、東部会
- Data Source
  KAKENHI-PROJECT-16K09337
[Presentation] Toll-like receptor 4を介した肝癌進展のメカニズム2017
- Author(s)
  三浦光一、石岡充彬、南慎一郎
- Organizer
  第103回　日本消化器病学会
- Data Source
  KAKENHI-PROJECT-16K09337
[Presentation] NASH動物モデルにおける腸内細菌叢と免疫機構の変化2016
- Author(s)
  Miura K, Ishioka M, Mimami S
- Organizer
  第41回日本肝臓学会東部会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-16K09337
[Presentation] Role of gut microbiota and Toll-like receptors in NAFLD2016
- Author(s)
  Miura K, Ishioka M, Mimami S, Ohnishi H
- Organizer
  International Congress on Obesity and Metabolic Syndrome
- Place of Presentation
  Seoul
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09337
[Presentation] Composition of gut microbiota and altered gut immune response in steatohepatitis and steatohepatitis-related liver cancer2016
- Author(s)
  Miura K, Ishioka M, Ohnishi H
- Organizer
  J-DDW
- Place of Presentation
  神戸
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09337
[Presentation] NASH発癌における腸内細菌の解析と病的意義2015
- Author(s)
  三浦光一、石岡充彬、大西洋英
- Organizer
  第19回日本肝臓学会大会
- Place of Presentation
  東京
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25460973
[Presentation] TLR4 signaling on macrophages promotes the progression of steatohepatitis and liver tumors in hepatocyte-specific PTEN deficient mice.2015
- Author(s)
  Miura K, Ishioka M, Ohnishi H
- Organizer
  Digestive Disease Week 2015
- Place of Presentation
  Washington, D.C, USA
- Year and Date
  2015-05-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460973
[Presentation] NASHおよびNASH発癌における腸内細菌の役割2014
- Author(s)
  三浦光一、大嶋重敏、大西洋英
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-25460973
[Presentation] NASH発癌モデルにおける腸内細菌叢の変化 -次世代シーケンサを用いた解析-2014
- Author(s)
  三浦光一、石岡充彬、大西洋英
- Organizer
  第40回日本肝臓学会東部会
- Place of Presentation
  東京
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-25460973
[Presentation] NASHおよびNASH発癌における腸内細菌とTLRの解析2014
- Author(s)
  三浦光一、大嶋重敏、大西洋英
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-30
- Data Source
  KAKENHI-PROJECT-25460973
[Presentation] TLR4を治療ターゲットにしたNASHおよびNASH発癌抑制への試み2013
- Author(s)
  三浦光一
- Organizer
  第17回日本肝臓学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460973
[Presentation] TLR4を治療ターゲットにしたNASHおよびNASH発癌抑制への試み2013
- Author(s)
  三浦光一
- Organizer
  日本消化器病学会
- Place of Presentation
  かごしま県民交流センター(鹿児島市)
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] NASHにおけるマクロファージのリクルートとTLR-MCP1-CCR2の役割2012
- Author(s)
  三浦光一
- Organizer
  JDDW2012
- Place of Presentation
  神戸国際展示場(神戸市)
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] マクロファージをターゲットにした肝線維化抑制の試み –NASHモデルでの検討-2012
- Author(s)
  三浦光一
- Organizer
  日本消化器病学会
- Place of Presentation
  京王プラザホテル(東京都)
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] Palmitic acid contributes to the progress of nonalcoholic steatohepatitis by activating inflammasome. (oral presentation) DDW2012
- Author(s)
  Kouichi Miura, Hirohide Ohnishi, Ekihiro Seki
- Organizer
  San Diego
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] Palmitic acid and TLR2 cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation.2012
- Author(s)
  Miura K
- Organizer
  DDW (AASLD)
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] 遊離脂肪酸によるインフラマゾーム活性化とNASH進展への役割2012
- Author(s)
  三浦光一
- Organizer
  日本肝臓学会
- Place of Presentation
  ホテル日航金沢(金沢市)
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] 炎症抑制にフォーカスをあてた肝線維化改善の試み2012
- Author(s)
  三浦光一
- Organizer
  日本肝臓学会東部肝
- Place of Presentation
  グランドプリンスホテル新高輪 (東京都)
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] 遊離脂肪酸によるインフラマゾーム活性化とNASH進展への役割2012
- Author(s)
  三浦光一、大西洋英
- Organizer
  第48回日本肝臓学会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] NASHにおけるマクロファージのリクルートとTLR-MCP1-CCR2の役割.2012
- Author(s)
  三浦光一, 石亦宏, 大嶋重敏, 後藤隆, 大西洋英
- Organizer
  JDDW2012
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] 炎症抑制にフォーカスをあてた肝線維化改善の試み2012
- Author(s)
  三浦光一、大嶋重敏、大西洋英
- Organizer
  第39回日本肝臓学会東部会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] マクロファージをターゲットにした肝線維化抑制の試み .NASHモデルでの検討-2012
- Author(s)
  三浦光一、大西洋英
- Organizer
  第98回日本消化器病学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] NASH動物モデルとしてのコリン欠乏食の有用性2011
- Author(s)
  三浦光一
- Organizer
  第97回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] CCR2 promotes the progression of NASH in mice2011
- Author(s)
  Kouichi Miura
- Organizer
  Digestive Disease Week (AASLD)
- Place of Presentation
  Chicago, USA
- Year and Date
  2011-05-09
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation]2011
- Author(s)
  三浦光一
- Organizer
  第47回日本肝臓学会
- Place of Presentation
  東京
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] NASH進展におけるToll-like receptor 2およびKupffer cellの役割 (ワークショップ)2011
- Author(s)
  三浦光一、石亦宏、大西洋英
- Organizer
  第47回日本肝臓学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] 肝非実質細胞の役割を中心に据えたNASH発症のメカニズム(シンポジウム)2011
- Author(s)
  三浦光一、大西洋英
- Organizer
  JDDW 2011
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] CCR2 promotes the progression of NASH in mice. (Oral presentation)2011
- Author(s)
  Miura K, Ohnishi H, Brenner DA, Seki E
- Organizer
  Chicago
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] NASH進展における自然免疫の役割2011
- Author(s)
  三浦光一
- Organizer
  JDDW2011
- Place of Presentation
  福岡市
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] NASH動物モデルとしてのコリン欠乏食の有用性(ミニシンポジウム)2011
- Author(s)
  三浦光一、大西洋英
- Organizer
  第97回日本消化器病学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] 肝非実質細胞の役割を中心に据えたNASH発症のメカニズム2011
- Author(s)
  三浦光一
- Organizer
  JDDW2011
- Place of Presentation
  福岡市
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] NASH進展における自然免疫の役割(シンポジウム)2011
- Author(s)
  三浦光一、石亦宏、大西洋英
- Organizer
  JDDW 2011
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] Toll-like Receptor(TLR) 2 in Kupffer cells plays a crucial role in the development of steatohepatitis in mice.2010
- Author(s)
  Kouichi Miura
- Organizer
  Digestive Disease Week(AASLD)
- Place of Presentation
  New Orleans, USA
- Year and Date
  2010-05-02
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] NASH進展におけるケモカイン様受容体CCR2の役割 (ポスター)2010
- Author(s)
  三浦光一, 石亦宏, 大西洋英
- Organizer
  JDDW2010
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] MCP-1 and CCR2 contribute to the development of NASH in mice2010
- Author(s)
  Miura K, Seki E, Brenner DA, Ohnishi H
- Organizer
  The 9 th JSH Single Topic Conference
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] NASH進展における腸内細菌叢と肝自然免疫の役割2010
- Author(s)
  三浦光一
- Organizer
  第96回日本消化器病学会総会
- Place of Presentation
  新潟市
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] NASH発症における耐糖能異常とToll様受容体の役割2010
- Author(s)
  三浦光一
- Organizer
  JDDW2010
- Place of Presentation
  横浜市
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] Toll-like Receptor (TLR) 2 in Kupffer cells plays a crucial role in the development of steatohepatitis in mice(Oral presentation)2010
- Author(s)
  Miura K, Inokuchi S, Ohnishi H, Brenner DA, Seki E
- Organizer
  New Orleans
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] NASH発症における耐糖能異常とToll様受容体の役割 (シンポジウム)2010
- Author(s)
  三浦光一, 石亦宏, 大西洋英
- Organizer
  JDDW2010
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] マウス肝線維化における肝細胞の上皮間葉移行の関与 (優秀演題)2010
- Author(s)
  三浦光一, 田浦康二朗, 大西洋英
- Organizer
  第46回日本肝臓学会
- Place of Presentation
  山形
- Data Source
  KAKENHI-PROJECT-22590714
[Presentation] NASH進展における腸内細菌叢と肝自然免疫の役割 (ワークショップ)2010
- Author(s)
  三浦光一, 石亦宏, 大西洋英
- Organizer
  第96回日本消化器病学会総会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-22590714

1. Ohnishi Hirohide (00313023)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. MASHIMA Hirosato (10261869)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Yamamoto Hironori (10311937)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. 矢野智則 (30438634)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. 永山学 (80741347)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. Kanno Atsushi (70509190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 堀江泰夫 (30282164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 濱田晋 (20451560)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 五家里栄 (00894891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 小谷和彦 (60335510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 真嶋浩聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 前田大地

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIURA KOICHI 三浦 光一

MIURA Koichi 三浦 光一

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クローン病由来大腸菌に対するバクテリオファージの新規検査治療法としての基礎的検討

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バクテリオファージを用いた非アルコール性脂肪性肝炎のコリン代謝評価と治療応用Principal Investigator

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非アルコール性脂肪性肝炎と心疾患における酸化HDLの役割解明

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analysis of small intestine-specific bacteria in Crohn's disease and an investigation of TNFSF15, a disease-prone gene

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The study to detect early-stage pancreatic cancer based on the data from molecular biology about the atrophic acinar cell surrounding carcinoma in situ.

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Application for bacterial therapy through Toll-like receptor 4 on cancer stem cellsPrincipal Investigator

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The molecular mechanism of autophagy participates in the onset and progression of acute pancreatitis

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The role of macrophages in NASH-related HCC and an application for therapyPrincipal Investigator

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Identification and functional analysis of SNARE proteins participating in the onset of acute pancreatitis

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Innate immunity and non-alcoholic steatohepatitis. A study for developing new immunologic therapy.Principal Investigator

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[Book] The Liver in Systemic Diseases2016

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[Book] NASH発症および進展における腸内細菌と肝自然免疫の役割消化器内科2011

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[Journal Article] Probiotics suppress nonalcoholic steatohepatitis and carcinogenesis progression in hepatocyte-specific PTEN knockout mice2022

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[Journal Article] Oxidized high-density lipoprotein shows a stepwise increase as fibrosis progresses in patients with nonalcoholic fatty liver disease.2021

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MIURA KOICHI 三浦光一

MIURA Koichi 三浦光一