NIKI Takeshi 仁木剛史

… Alternative Names

仁木剛史ニキタケシ

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Researcher Number	90377193
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2013 – 2014: 北海道大学, (連合)農学研究科(研究院), 准教授 2010 – 2011: 北海道大学, 大学院・農学研究院, 准教授 2005 – 2006: 新潟大学, 医歯学系, 助手
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / Neurology Except Principal Investigator General pharmacology
Keywords	Principal Investigator パーキンソン病 / DJ-1 / 酸化ストレス / Nrf2 / PTEN / ジスルフィド結合 / PARK7 / 活性酸素 / 神経分子病態学 Except Principal Investigator 中枢摂食制御 … More / 摂食中枢 / 視床下部 / 遺伝子発現 / ニューロペプチドY / 摂食関連ペプチド / 中核摂食制御 Less

パーキンソン病関連因子DJ-1の還元による新規機能回復ならびに酸化抑制薬の開発Principal Investigator
- Principal Investigator
  
  仁木剛史
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Hokkaido University
Antioxidative defense mechanism of DJ-1, parkinson's disease related genePrincipal Investigator
- Principal Investigator
  
  NIKI Takeshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Hokkaido University
RNAiを用いた摂食関連遺伝子の機能ターゲッティング法の開発
- Principal Investigator
  
  樋口宗史
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Niigata University

All 2013 2012 2011 2010 2007 2006

All Journal Article Presentation

[Journal Article] Neuroprotective Function of DJ-1 against Parkinson's Disease2013
- Author(s)
  Ariga H. Takahashi-Niki K, Kato I, Maita H, Niki T,, Iguchi-Ariga SM
- Journal Title
  
  SM Oxidative Medicine and Cellular Longevity
  
  Volume: 683920 Pages: 683920-683920
- DOI
  10.1155/2013/683920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790970, KAKENHI-PROJECT-24650191, KAKENHI-PROJECT-25430059, KAKENHI-PROJECT-25830071
[Journal Article] Identification of DJ-1-associated regions on human genes from SH-SY5Y cells using chromatin immunoprecipitation sequence technique.2013
- Author(s)
  Yamane T, Sugimoto N, Maita H, Watanabe, K, Takahashi-Niki K, Maita C, Kato-Ose I, Ishikawa S, Gao J, Kitaura H, Niki T, Iguchi-Ariga S.M.M. Ariga H.
- Journal Title
  
  Molecular Biology
  
  Volume: 3 Issue: 01
- DOI
  10.4172/2168-9547.1000115
- NAID
  120005646334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430059
[Journal Article] Identification of the recognition sequence and target proteins for DJ-1 protease2013
- Author(s)
  Mitsugi H., Niki T., Takahashi-Niki K, Tanimura K., Yoshizawa-Kumagaye K, Tsunemi M.,Iguchi-Ariga SM, Ariga H.
- Journal Title
  
  FEBS Letters
  
  Volume: 587(16) Issue: 16 Pages: 2493-9
- DOI
  10.1016/j.febslet.2013.06.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790970, KAKENHI-PROJECT-25430059
[Journal Article] DJ-1 cooperates with PYCR1 in cell protection against oxidative stress.2013
- Author(s)
  Yasuda, T.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 436 Issue: 2 Pages: 289-294
- DOI
  10.1016/j.bbrc.2013.05.095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24650191, KAKENHI-PROJECT-25430059
[Journal Article] Stimulation of vesicular monoamine transporter 2 activity by DJ-1 in SH-SY5Y cells Shizuma Ishikawa2012
- Author(s)
  Yuki Tanaka, Kazuko Takahashi-Niki, Takeshi Niki, Hiroyoshi Arigab, Sanae M. M. Iguchi-Ariga
- Journal Title
  
  Biochem. Biochemical and Biophysical Research
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790809
[Journal Article] A novel signaling pathway mediated by the nuclear targeting of C-terminal fragments of mammalian Patched 12011
- Author(s)
  Kagawa, H., Shino, Y., Kobayashi, D., Demizu, S., Shimada, M., Ariga, H., Kawahara, H.
- Journal Title
  
  PLoS ONE
  
  Volume: 6 Issue: 51 Pages: 39718-39731
- DOI
  10.1074/jbc.m110.137034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390014, KAKENHI-PROJECT-22790809
[Journal Article] Potentiation by neuropeptide Y of histamine H_1 receptor-mediated contraction in rat blood vessels.2007
- Author(s)
  Piao H., Nagai S., Tsurumaki T., Niki T., Higuchi H.
- Journal Title
  
  Vascul. Pharmacol. 46
  
  Pages: 260-270
- Data Source
  KAKENHI-PROJECT-17659071
[Journal Article] NPY-Y5受容体ノックアウトマウスの摂食ペプチド発現の制御と摂食2006
- Author(s)
  樋口宗史, 山口剛, 仁木剛史
- Journal Title
  
  日薬理誌 127
  
  Pages: 92-96
- NAID
  10017495235
- Data Source
  KAKENHI-PROJECT-17659071
[Presentation] DJ-1とその結合タンパク質の相互作用に対する酸化ストレスの影響2013
- Author(s)
  仁木剛史、仁木（高橋）加寿子、遠藤仁郎、中川翔太、有賀寛芳、有賀（井口）早苗
- Organizer
  日本生化学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-25430059
[Presentation] Oxidative stress-response by DJ-1 and its binding compounds2012
- Author(s)
  Niki, T., Takahashi-Niki, K., Okamoto, A., Endo, J., Ariga, H., Iguchi-Ariga, S. M. M.
- Organizer
  The 41th annual meeting of the Society for Neuroscience
- Place of Presentation
  Washington DC, USA
- Year and Date
  2012-11-12
- Data Source
  KAKENHI-PROJECT-22790809
[Presentation] Oxidative stress-response by DJ-1 and its binding compounas2011
- Author(s)
  仁木剛史
- Organizer
  Neuroscience 2011
- Place of Presentation
  Walter E.Washington Convention Center(アメリカワシントンDC)
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-22790809
[Presentation] DJ-1の抗酸化ストレスセンサーとしての役割2011
- Author(s)
  仁木(高橋)加寿子、仁木剛史、辻美咲、北浦廣剛、有賀(井口)早苗、有賀寛芳
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22790809
[Presentation] パーキンソン病原因遺伝子産物DJ-1とその結合化合物による酸化ストレス誘導Nrf2転写活性化能に対する影響2011
- Author(s)
  仁木剛史、仁木(高橋)加寿子、岡本麻美、遠藤仁朗、瀬在和哉、有賀寛芳、有賀(井口)早苗
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22790809
[Presentation] バーキンソン病原因遺伝子産物DJ-1とその結合化合物による酸化ストレス誘導Nrf2転写活性化能に対する影響2011
- Author(s)
  仁木剛史
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-22790809
[Presentation] パーキンソン病原因遺伝子DJ-1の抗酸化ストレス機能の解析2010
- Author(s)
  仁木加寿子、仁木剛史、有賀(井口)早苗、有賀寛芳
- Organizer
  BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22790809
[Presentation] パーキンソン病原因遺伝子産物DJ-1とその結合化合物による酸化ストレス応答2010
- Author(s)
  仁木剛史、仁木(高橋)加寿子、遠藤仁郎、瀬在和哉、岡本麻美、有賀寛芳、有賀(井口)早苗
- Organizer
  BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸)
- Data Source
  KAKENHI-PROJECT-22790809
[Presentation] パーキンソン病原因遺伝子産物DJ-1とその結合化合物による酸化ストレス応答2010
- Author(s)
  仁木剛史
- Organizer
  第33回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  兵庫県神戸市中央区神戸国際展示場
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22790809

1. NIKI Kazuko (50447645)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
2. 樋口宗史 (30150337)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 有賀寛芳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NIKI Takeshi 仁木 剛史

仁木 剛史 ニキ タケシ

Research Projects

Research Products

Co-Researchers

パーキンソン病関連因子DJ-1の還元による新規機能回復ならびに酸化抑制薬の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Antioxidative defense mechanism of DJ-1, parkinson's disease related genePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

RNAiを用いた摂食関連遺伝子の機能ターゲッティング法の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Neuroprotective Function of DJ-1 against Parkinson's Disease2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of DJ-1-associated regions on human genes from SH-SY5Y cells using chromatin immunoprecipitation sequence technique.2013

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Identification of the recognition sequence and target proteins for DJ-1 protease2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DJ-1 cooperates with PYCR1 in cell protection against oxidative stress.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Stimulation of vesicular monoamine transporter 2 activity by DJ-1 in SH-SY5Y cells Shizuma Ishikawa2012

Author(s)

Journal Title

Data Source

[Journal Article] A novel signaling pathway mediated by the nuclear targeting of C-terminal fragments of mammalian Patched 12011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Potentiation by neuropeptide Y of histamine H_1 receptor-mediated contraction in rat blood vessels.2007

Author(s)

Journal Title

Data Source

[Journal Article] NPY-Y5受容体ノックアウトマウスの摂食ペプチド発現の制御と摂食2006

Author(s)

Journal Title

NAID

Data Source

[Presentation] DJ-1とその結合タンパク質の相互作用に対する酸化ストレスの影響2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Oxidative stress-response by DJ-1 and its binding compounds2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Oxidative stress-response by DJ-1 and its binding compounas2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] DJ-1の抗酸化ストレスセンサーとしての役割2011

NIKI Takeshi 仁木剛史

仁木剛史ニキタケシ