Handa Osamu 半田修

… Alternative Names

半田修ハンダオサム

HANDA Osamu 半田修

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Researcher Number	90381970
Other IDs
Affiliation (Current)	2025: 川崎医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 川崎医科大学, 医学部, 准教授 2019: 川崎医科大学, 医学部, 講師 2018: 京都府立医科大学, 医学(系)研究科(研究院), 特任講師 2015 – 2017: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2012: 京都府立医科大学, 医学(系)研究科(研究院), 助教 … More 2012: 京都府立医科大学, 医学(系)研究科(研究院), 講師 2009 – 2011: 京都府立医科大学, 医学研究科, 助教 2007: Kyoto Prefectural University of Medicine, Department of Biomedical Safety Science, Associate Professor 2006 – 2007: 京都府立医科大学, 医学部・生体安全医学講座(寄附講座), 講師 2006: 京都府立医科大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Gastroenterology / Risk sciences of radiation/Chemicals Except Principal Investigator Gastroenterology / Rehabilitation science/Welfare engineering / General internal medicine (including Psychosomatic medicine)
Keywords	Principal Investigator バイオマーカー / サイトカイン / 生物学的製剤 / 腸管局所サイトカイン / 腸内細菌 / 酪酸産生菌 / 手術歴 / 粘膜関連細菌叢 / クローン病 / Helicobacter pylori … More / 非侵襲 / 感受性試験 / 抗生剤感受性 / 迅速 / 安価 / ヘリコバクター・ピロリ菌 / 感染診断 / PCR / ヘリコバクター・ピロリ / 唾液 / keratinocvte / genomic analysis / ultra violet / toxicology / cosmetic additives / ケラチノサイト / 遺伝子解析 / 紫外線照射 / 毒性発現 / 化粧品添加物 … More Except Principal Investigator 温熱療法 / 十二指腸粘膜免疫応答 / 十二指腸粘膜バリア機構 / 十二指腸粘膜バリア / streptococcus属 / 腸内細菌 / 機能性ディスペプシア / タイトジャンクション / 十二指腸粘膜 / Streptococcus属 / 腸内細菌叢 / 機能性ディスぺプシア / リキッドバイオプシー / ペプチド分析 / 先制医療 / 質量分析計 / ペプチドマーカー / 質量分析 / ペプチド / 早期発見 / バイオマーカー / 大腸癌 / anti-inflammatory action / hyperthermia / Rheumatoid arthritis / コラーゲン惹起関節炎 / 全身温熱療法 / コラーゲン惹起免疫関節炎 / 細胞接着分子 / 血管内皮細胞 / IL-8 / 炎症性サイトカイン / 転写因子NF-kB / 熱ショック蛋白 / CINC-1 / TNF-alpha / Trinitrobenzesulfonic acid / 粘膜治癒 / 抗炎症作用 / 炎症性腸疾患 / クローン病 / 潰瘍性大腸炎 / 一酸化炭素 / メラノーマ / CD3-LAK細胞 / CD62L+細胞 / colon26大腸癌細胞 / 免疫細胞療法 / 大腸癌細胞 / 癌ワクチン / ナイーブT細胞 / 免疫療法 / 癌 Less

Crohn病の腸内細菌叢と局所サイトカインに基づく生物学的製剤の選択基準の確立Principal Investigator
- Principal Investigator
  
  半田修
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kawasaki Medical School
Analysis of endoscopic brush samples identified mucosa associated dysbiosis and the expression of tight junction protein in functional dyspepsia.
- Principal Investigator
  
  Fukui Akifumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine
Precision Medicine for Colon Cancer by High-throughput Analysis by Quantitative Mass Spectrometry
- Principal Investigator
  
  Naito Yuji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine
Development of practical method for the diagnosis of infection and antibiotics susceptibility of H. pyloriPrincipal Investigator
- Principal Investigator
  
  Handa Osamu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine
The effect of carbon monoxide in the intestinal inflammation
- Principal Investigator
  
  TAKAGI Tomohisa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine
Development of hyperthermicimmunetherapy for cancer
- Principal Investigator
  
  KOKURA Satoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Kyoto Prefectural University of Medicine
Hyperthermic treatment for early stage of rheumatoid arthritis
- Principal Investigator
  
  KOKURA Satoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Kyoto Prefectural University of Medicine
Prediction of the cytotoxicity of additives in cosmetics on UV-exposed human skin keratinocytesPrincipal Investigator
- Principal Investigator
  
  HANDA Osamu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto Prefectural University of Medicine

[Book] 日本がん予防学会. NEWS LETTER.「高校生対象のピロリ発癌撲滅計画」 No86. 20152015
- Author(s)
  半田　修
- Total Pages
  1
- Publisher
  日本がん予防学会.
- Data Source
  KAKENHI-PROJECT-15K08956
[Journal Article] Reduced abundance of butyric acid-producing bacteria in the ileal mucosa-associated microbiota of ulcerative colitis patients2023
- Author(s)
  Osawa Motoyasu、Handa Osamu、Fukushima Shinya、Matsumoto Hiroshi、Umegaki Eiji、Inoue Ryo、Naito Yuji、Shiotani Akiko
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 73 Issue: 1 Pages: 77-83
- DOI
  10.3164/jcbn.22-86
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06758
[Journal Article] Serial Changes in Intestinal Stenotic Stiffness in Patients with Crohn’s Disease Treated with Biologics: A Pilot Study Using Ultrasound Shear Wave Elastography2023
- Author(s)
  Matsumoto H, Hata J, Yo S, Sasahira M, Misawa H, Oosawa M, Handa O, Umegami E, Shiotani A.
- Journal Title
  
  The Turkish Journal of Gastroenterology
  
  Volume: 34 Issue: 10 Pages: 1006-1013
- DOI
  10.5152/tjg.2023.22768
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06758
[Journal Article] Reduction of butyric acid-producing bacteria in the ileal mucosa-associated microbiota is associated with the history of abdominal surgery in patients with Crohn’s disease2023
- Author(s)
  Handa Osamu、Miura Hiroto、Gu Tingting、Osawa Motoyasu、Matsumoto Hiroshi、Umegaki Eiji、Inoue Ryo、Naito Yuji、Shiotani Akiko
- Journal Title
  
  Redox Report
  
  Volume: 28 Issue: 1 Pages: 1-7
- DOI
  10.1080/13510002.2023.2241615
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06758
[Journal Article] Higher Levels of Streptococcus in Upper Gastrointestinal Mucosa Associated with Symptoms in Patients with Functional Dyspepsia.2020
- Author(s)
  Fukui A, Takagi T, Naito Y, Inoue R, Kashiwagi S, Mizushima K, Inada Y, Inoue K, Harusato A, Dohi O, Okayama T, Katada K, Kamada K, Uchiyama K, Ishikawa T, Handa O, Itoh Y, Nakagawa M
- Journal Title
  
  Digestion
  
  Volume: 101 Issue: 1 Pages: 38-45
- DOI
  10.1159/000504090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09358
[Journal Article] Secreted protein acidic and rich in cysteine functions in colitis via IL17A regulation in mucosal CD4(+) T cells.2018
- Author(s)
  Tanaka M, Takagi T, Naito Y, Uchiyama K, Hotta Y, Toyokawa Y, Ushiroda C, Hirai Y, Aoi W, Higashimura Y, Mizushima K, Okayama T, Katada K, Kamada K, Ishikawa T, Handa O, Itoh Y.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 33 Issue: 3 Pages: 671-680
- DOI
  10.1111/jgh.13842
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09322, KAKENHI-PROJECT-16H05289, KAKENHI-PROJECT-16K16281, KAKENHI-PROJECT-17H02176
[Journal Article] Selected reaction monitoring for colorectal cancer diagnosis using a set of five serum peptides identified by BLOTCHIP((R))-MS analysis2018
- Author(s)
  Uchiyama, K. Naito, Y. Yagi, N. Mizushima, K. Higashimura, Y. Hirai, Y. Dohi, O. Okayama, T. Yoshida, N. Katada, K. Kamada, K. Handa, O. Ishikawa, T. Takagi, T. Konishi, H. Nonaka, D. Asada, K. Lee, L. J. Tanaka, K. Kuriu, Y. Nakanishi, M. Otsuji, E. Itoh, Y.
- Journal Title
  
  J Gastroenterol
  
  Volume: 印刷中 Issue: 11 Pages: 1179-1185
- DOI
  10.1007/s00535-018-1448-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05289, KAKENHI-PROJECT-18K05475, KAKENHI-PROJECT-18K06224
[Journal Article] The protective effect of orally administered redox nanoparticle on intestinal ischemia-reperfusion injury in mice.2018
- Author(s)
  Ueda T, Takagi T, Katada K, Iida T, Mizushima K, Dohi O, Okayama T, Yoshida N, Kamada K, Uchiyama K, Handa O, Ishikawa T, Konishi H, Naito Y, Nagasaki Y, Itoh Y.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 495 Issue: 2 Pages: 2044-2049
- DOI
  10.1016/j.bbrc.2017.11.204
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10512, KAKENHI-PROJECT-16H05289, KAKENHI-PROJECT-18H04160
[Journal Article] Serum metabolomics analysis for early detection of colorectal cancer2017
- Author(s)
  Kazuhiko Uchiyama, Nobuaki Yagi, Katsura Mizushima, Yasuki Higashimura, Yasuko Hirai, Tetsuya Okayama, Naohisa Yoshida, Kazuhiro Katada, Kazuhiro Kamada, Osamu Handa, Takeshi Ishikawa, Tomohisa Takagi, Hideyuki Konishi, Yoshiaki Kuriu, Masayoshi Nakanishi, Eigo Otsuji, Yoshito Itoh, Yuji Naito
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 52(6) Issue: 6 Pages: 677-694
- DOI
  10.1007/s00535-016-1261-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08313, KAKENHI-PROJECT-16H05289
[Journal Article] BTB and CNC Homolog 1 (Bach1) Deficiency Ameliorates TNBS Colitis in Mice: Role of M2 Macrophages and Heme Oxygenase-12013
- Author(s)
  Harusato, A. Naito, Y. Takagi, T. Uchiyama, K. Mizushima, K. Hirai, Y. Higashimura, Y. Katada, K. Handa, O. Ishikawa, T. Yagi, N. Kokura, S. Ichikawa, H. Muto, A. Igarashi, K. Yoshikawa, T.
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 19 Issue: 4 Pages: 740-753
- DOI
  10.1097/mib.0b013e3182802968
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590705, KAKENHI-PROJECT-22590706, KAKENHI-PROJECT-23790322, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-25460959, KAKENHI-PUBLICLY-23117702
[Journal Article] Hemopexin is upregulated in rat intestinal mucosa injured by indomethacin2012
- Author(s)
  Takagi T, Naito Y, Okada H, Takaoka M, Oya-Ito T, Yamada S, Hirai Y, Mizushima K, Yoshida N, Kamada K,Katada K, Uchiyama K, Ishikawa T, Handa O, Yagi N, Konishi H, Kokura S, Ichikawa H, Yoshikawa T
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: J Gastroenterol Hepatol Issue: s3 Pages: 70-75
- DOI
  10.1111/j.1440-1746.2012.07076.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700765, KAKENHI-PROJECT-22590706, KAKENHI-PROJECT-24500986
[Journal Article] Colonic insufflation with carbon monoxide gas inhibits the development of intestinal inflammation in rats2012
- Author(s)
  Takagi, T. Naito, Y. Uchiyama, K. Okuda, T. Suzuki, T. Tsuboi, H. Mizushima, K. Handa, O. Yagi, N. Ichikawa, H. Yoshikawa, T.
- Journal Title
  
  Med Gas Res
  
  Volume: 2 Issue: 1 Pages: 23-23
- DOI
  10.1186/2045-9912-2-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590705, KAKENHI-PROJECT-22590706
[Journal Article] Endogenous hydrogen sulfide is an anti-inflammatory molecule in dextran sodium sulfate-induced colitis in mice2011
- Author(s)
  Hirata I, Naito Y, Takagi T, Mizushima K, Suzuki T, Omatsu T, Handa O, Ichikawa H, Ueda H, Yoshikawa T
- Journal Title
  
  Dig Dis Sci
  
  Volume: 56(5) Issue: 5 Pages: 1379-86
- DOI
  10.1007/s10620-010-1461-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590706
[Journal Article] Carbon monoxide liberated from carbon monoxide-releasing molecule exerts an anti-inflammatory effect on dextran sulfate sodium-induced colitis in mice2011
- Author(s)
  Takagi T, Naito Y, Uchiyama K, Suzuki T, Hirata I, Mizushima K, Tsuboi H, Hayashi N, Handa O, Ishikawa T, Yagi N, Kokura S, Ichikawa H, Yoshikawa T
- Journal Title
  
  Dig Dis Sci
  
  Volume: 56 Issue: 6 Pages: 1663-71
- DOI
  10.1007/s10620-010-1484-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390184, KAKENHI-PROJECT-22590706
[Journal Article] Adoptive cellular therapy enhances the helper T cell response and reduces the number of regulatory T cells2011
- Author(s)
  Ishikawa T, Kokura S, Sakamoto N, Matsumoto T, Funaki J, Adachi S, Okayama T, Uchiyama K, Handa O, Takagi T, Yagi N, Ando T, Uno K, Naito U and Yoshikawa T
- Journal Title
  
  EXPERIMENTAL AND THERAPEUTICMEDICINE
  
  Volume: 2 Pages: 737-743
- Data Source
  KAKENHI-PROJECT-21590770
[Journal Article] Rebamipide promotes healing of colonic ulceration through enhanced epithelial restitution2011
- Author(s)
  Takagi T, Naito Y, Uchiyama K, Okuda T, Mizushima K, Suzuki T, Handa O, Ishikawa T, Yagi N, Kokura S, Ichikawa H, Yoshikawa T
- Journal Title
  
  World J Gastroenterol
  
  Volume: 17(33) Issue: 33 Pages: 3802-9
- DOI
  10.3748/wjg.v17.i33.3802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590706
[Journal Article] Suppression of indomethacin-induced apoptosis in the small intestine due to Bach1 deficiency2011
- Author(s)
  Harusato A, Naito Y, Takagi T, Uchiyama K, Mizushima K, Hirai Y, Yamada S, Tuji T, Yoriki H, Horie R, Inoue K, Fukumoto K, Handa O, Ishikawa T, Kokura S, Minamiyama Y, Ichikawa H, Muto A, Igarashi K, Yoshikawa T
- Journal Title
  
  Free Radic Res
  
  Volume: 45(6) Issue: 6 Pages: 717-727
- DOI
  10.3109/10715762.2011.574287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500767, KAKENHI-PROJECT-22590706, KAKENHI-PUBLICLY-23117702, KAKENHI-PROJECT-23790322
[Journal Article] Inhalation of carbon monoxide ameliorates TNBS-induced colitis in mice through the inhibition of TNF-alpha expression2010
- Author(s)
  Takagi T, Naito Y, Mizushima K, Akagiri S, Suzuki T, Hirata I, Omatsu T, Handa O, Kokura S, Ichikawa H, Yoshikawa T
- Journal Title
  
  Dig Dis Sci
  
  Volume: 55 Issue: 10 Pages: 2797-2804
- DOI
  10.1007/s10620-009-1112-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590706
[Journal Article] Antitumor effect of pretreatment for colon cancer cells with hyperthermia plus geranylgeranylacetone in experimental metastasis models and a subcutaneous tumor model of colon cancer in mice.2010
- Author(s)
  Okayama T, Kokura S, Ishikawa T, Adachi S, Hattori T, Takagi T, Handa O, Naito Y, Yoshikawa
- Journal Title
  
  Int J Hyperthermia
  
  Volume: 25 Pages: 141-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590770
[Journal Article] Carbon monoxide enhance colonic epithelial restitution via FGF15 derived from colonic myofibroblasts2010
- Author(s)
  Uchiyama K, Naito Y, Takagi T, Mizushima K, Hayashi N, Harusato A, Hirata I, Omatsu T, Handa O, Ishikawa T, Yagi N, Kokura S, Yoshikawa T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 391 Issue: 1 Pages: 1122-6
- DOI
  10.1016/j.bbrc.2009.12.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390184, KAKENHI-PROJECT-22590706
[Journal Article] Antitumor effect of pretreatment for colon cancer cells with hyperthermia plus geranylgeranylacetone in experimental metastasis models and a subcutaneous tumor model of colon cancer in mice.2009
- Author(s)
  Okayama T, Kokura S, Ishikawa T, Adachi S, Hattori T, Takagi T, Handa O, Naito Y, Yoshikawa
- Journal Title
  
  Int J Hyperthermia 25
  
  Pages: 141-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590770
[Journal Article] Whole body hyperthermia improves obesity-induced insulin resistance in diabetic mice2007
- Author(s)
  Kokura, S., Adachi, S., Manabe, E., Mizushima, K., Hattori, T., Okuda, T., Nakabe, N., Handa, O., Takagi, T., Naito, Y., Yoshida, N., Yoshikawa, T
- Journal Title
  
  Int J Hyperthermia 23
  
  Pages: 259-265
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500417
[Journal Article] Hyperthermia ameliorates 2, 4, 6- Trinitrobenzene Sulphonic Acid-induced colitis in rats: the role of heat shock proteins2007
- Author(s)
  Kokura, S., Yoshida, N., Okuda, T., Nakabe, N., Sakamoto, N., Isozaki, Y., Hattori, T., Handa, O., Takagi, T., Naito, Y., Yoshikawa, T
- Journal Title
  
  Int J Hyperthermia 23
  
  Pages: 17-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500417
[Journal Article] Hyperthermia attenuates TNF-alpha-induced up regulation of endothelial cell adhesion molecules in human arterial endothelial cells2007
- Author(s)
  Nakabe, N., Kokura, S., Shimozawa, M., Katada, K., Sakamoto, N., Ishikawa, T., Handa, O., Takagi, T., Naito, Y., Yoshida, N., Yoshikawa, T
- Journal Title
  
  Int J Hyperthermia 23
  
  Pages: 217-224
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500417
[Journal Article] Methylparaben potentiates UV-induced damage of skin keratinocytes2006
- Author(s)
  Handa, O., Kokura, S., Adachi, S., Takagi, T., Naito, Y., Tanigawa, T., Yoshida, N., Yoshikawa, T
- Journal Title
  
  Toxicology 227(1-2)
  
  Pages: 62-72
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18510062
[Journal Article] Methylparaben potentiates UV-induced damage of skin keratinocytes.2006
- Author(s)
  半田修, 古倉聡, 足立聡子, 高木智久, 内藤裕二, 谷川徹, 吉田憲正, 吉川敏一
- Journal Title
  
  Toxicology 227巻・1-2号
  
  Pages: 62-72
- Data Source
  KAKENHI-PROJECT-18510062
[Journal Article] Methylparaben potentiates UV-induced damage of skin keratinocytes2006
- Author(s)
  半田修、古倉聡、足立聡子、高木智久、内藤裕二、谷川徹、吉田憲正、吉川敏一
- Journal Title
  
  Toxicology 227巻
  
  Pages: 62-72
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510062
[Journal Article] Hyperthermia attenuates TNF-alpha-induced up regulation of endothelial cell adhesion molecules in human arterial endothelial cells
- Author(s)
  Nakabe;Kokura, Shimozawa;Katada, Sakamoto;Ishikawa, Handa;Takagi, Naito;Yoshida, Yoshikawa
- Journal Title
  
  International Journal of Hyperthermia (in press)
- Data Source
  KAKENHI-PROJECT-18500417
[Journal Article] Decrease of the regulatory T cells population by adoptive T cell transfer in a mouse colorectal cancer transplant model
- Author(s)
  Tsuguhiro Matsumoto, Satoshi Kokura**, Takeshi Ishikawa, Jun Funaki, Satoko Adachi, Koji Mori, Naoyuki Sakamoto, Kazuhiro Katada, Kazuhiro Kamada, Nobuaki Yagi, Osamu Handa, Tomohisa Takagi, Kazuhiko Uchiyama, Yuji Naito, and Toshikazu Yosikawa
- Journal Title
  
  Oncology Research
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-21590770
[Presentation] The relationship between endoscopic score and serum trough concentration of infliximab in patients with inflammatory bowel disease.2023
- Author(s)
  Handa O, Matsumoto H, Shiotani A.
- Organizer
  第105回日本消化器内視鏡学会総会. International Session: パネルディスカッション1
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06758
[Presentation] クローン病患者における粘膜関連細菌叢の解析2022
- Author(s)
  半田　修、大澤元保、松本正憲、松本啓志、井上　亮、内藤裕二、梅垣英次、塩谷昭子
- Organizer
  第60回日本小腸学会学術集会
- Data Source
  KAKENHI-PROJECT-22K06758
[Presentation] 機能性ディスペプシア患者と健常人との粘膜内細菌叢の比較検討2019
- Author(s)
  福居顕文、髙木智久、半田　修、内藤裕二
- Organizer
  第15回日本消化管学会総会学術集会ワークショップ4「微生物叢から見た消化管病態の新知見」
- Data Source
  KAKENHI-PROJECT-17K09358
[Presentation] 内視鏡化採取検体を用いた機能性ディスペプシア患者と健常人との粘膜内細菌叢の比較検討2018
- Author(s)
  福居顕文、髙木智久、半田　修、内藤裕二
- Organizer
  日本消化器病学会近畿支部109回例会シンポジウム1「消化管診療の最前線」
- Data Source
  KAKENHI-PROJECT-17K09358
[Presentation] 若年者に対する胃癌予防のあり方 Session overview2017
- Author(s)
  半田修
- Organizer
  第23回日本ヘリコバクター学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08956
[Presentation] 高齢者の胃粘膜病変2017
- Author(s)
  半田修
- Organizer
  第20回日本高齢消化器病学会
- Data Source
  KAKENHI-PROJECT-15K08956
[Presentation] 基本から学ぼう、胃潰瘍・胃癌とピロリ菌2017
- Author(s)
  半田修
- Organizer
  第 45 回日本潰瘍学会
- Data Source
  KAKENHI-PROJECT-15K08956
[Presentation] Multi-center prospective “test and treat” study on Helicobacter pylori for high school students in Kyoto Prefecture.2017
- Author(s)
  Osamu Handa, Yuji Naito et al.
- Organizer
  Digestive Disease Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08956
[Presentation] Multi-center prospective study on Helicobacter pylori eradication therapy for high school students in Kyoto Prefecture2016
- Author(s)
  Handa O, Naito Y, Majima A, Suyama Y, Onozawa Y, Dohi O, Okayama T, Yoshida N, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, KonishiH, Ando T, Itoh Y
- Organizer
  米国消化器病学会2016
- Place of Presentation
  サンディエゴ、米国
- Year and Date
  2016-05-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08956
[Presentation] 京都発高校生除菌の課題2016
- Author(s)
  半田　修、内藤裕二、陶山遥介、間嶋　淳、小野澤由里子、堅田和弘、安藤貴志、伊藤義人、吉川敏一
- Organizer
  第22回日本ヘリコバクター学会学術集会
- Place of Presentation
  別府
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15K08956
[Presentation] The screening project of Helicobacter pylori for high school students in Kyoto Prefecture2016
- Author(s)
  Handa O, Naito Y, Majima A, Katada K, Takagi T, Itoh Y, Yoshikawa T
- Organizer
  アジア太平洋消化器病週間（APDW）2016
- Place of Presentation
  神戸
- Year and Date
  2016-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08956
[Presentation] 京都発高校生ピロリ除菌による胃がん撲滅計画.2016
- Author(s)
  半田　修.
- Organizer
  京都府医師会学術講演会、京都消化器医会定例学術講演会.
- Place of Presentation
  京都
- Year and Date
  2016-02-13
- Data Source
  KAKENHI-PROJECT-15K08956
[Presentation] H.pylori 除菌後の経過年数からみる除菌後胃癌の特徴.2015
- Author(s)
  間嶋　淳、半田修、内藤裕二.
- Organizer
  第89回日本消化器内視鏡学会総会
- Place of Presentation
  名古屋
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-15K08956
[Presentation] 若年世代におけるヘリコバクター･ピロリ感染調査と除菌による将来の胃がん発症の予防を目指して～日本から胃癌をなくすために～「行政と共に医師会が取り組むべき胃がん対策」2015
- Author(s)
  半田　修、間嶋　淳、内藤裕二.
- Organizer
  京都府医師会消化器癌検診委員会.
- Place of Presentation
  京都
- Year and Date
  2015-05-01
- Data Source
  KAKENHI-PROJECT-15K08956
[Presentation] 京都府における高校生除菌スタートアップ.2015
- Author(s)
  半田　修、堅田和弘、陶山遥介、間嶋　淳、小野澤由里子、安藤貴志、横江信義、内藤裕二.
- Organizer
  第21回日本ヘリコバクター学会学術集会.
- Place of Presentation
  神戸
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15K08956
[Presentation] Clinicopathological changes of early gastric cancer over time from successful eradication of helicobacter pylori.2015
- Author(s)
  Majima A, Handa O, Iwai N, Ueda T, Onozawa Y, Kitaichi T, Horii Y, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Uchiyama K, Ishikawa T, Takagi T, Konishi H, Naito Y, Itoh Y.
- Organizer
  United European Gastroenterology Week 2015
- Place of Presentation
  Barcelona, Spain.
- Year and Date
  2015-10-27
- Data Source
  KAKENHI-PROJECT-15K08956
[Presentation] シンポジウム 1「炎症性腸疾患の免疫病態 -Bench&Bedside Heme oxygenase-1発現制御性転写因子Bach1の抑制は腸管炎症を改善する.2011
- Author(s)
  高木智久、内藤裕二、春里暁人、辻俊史、寄木浩行、堀江隆介、内山和彦、堅田和弘、水島かつら、平井泰子、半田修、八木信明、市川寛、武藤哲彦、五十嵐和彦、吉川敏一
- Organizer
  第48回日本消化器免疫学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22590706
[Presentation] Impact of adoptive T cell therapy on the cytokines production and the number of Treg in peripheral blood of patients with cancer2010
- Author(s)
  Ishikawa T, Kokura S, Sakamoto N, Funaki J, Adachi S, Matsumoto T, Matsuura Y, Okayama T, Yoshida N, Uchiyama K, Takagi T, Handa O, Konishi H, Wakabayashi N, Yagi N, Naito Y, Uno K, Yoshikawa T
- Organizer
  9th International Conference of The Asian Clinical Oncology Society
- Place of Presentation
  Gifu
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-21590770
[Presentation] Carbon monoxide (CO)-saturated sodium enema ameliorates trinitrobenzene sulfonic acid-induced colitis in rats2010
- Author(s)
  Takagi T, Naito Y, Uchiyama K, Okuda T, Hirata I, Omatsu T, Mizushima K, Hayashi N, Handa O, Ishikawa T, Yagi N, Kokura S, Yoshiakwa T
- Organizer
  The 6thInternational Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  Kyoto
- Year and Date
  2010-06-14
- Data Source
  KAKENHI-PROJECT-22590706
[Presentation] Hyperthermia enhances the anti-tumor activity of adoptive transfer of naive T cells2010
- Author(s)
  Tsuguhiro Matsumoto, Satoshi Kokura, Takeshi Ishikawa, Jun Funaki, Satoko Adachi, Tetsuya Okayama, Naohisa Yoshida, Naoyuki Sakamoto, Kazuhiko Uchiyama, Tomohisa Takagi, Osamu Handa, Hideyuki Konishi, Naoki Wakabayashi, Nobuaki Yagi, Yuji Naito, Akiko Kato, Keisuke Tomita, Tatsuji Enoki, Toshikazu Yoshikawa
- Organizer
  101th AACR
- Place of Presentation
  ワシントンDC
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-21590770
[Presentation] Adoptive T cell therapy shifts the secretion ability of cytokines to Th1 and decreases the number of Tregs in patients with cancer2010
- Author(s)
  Ishikawa T, Kokura S, Sakamoto N, Matsumoto T, Funaki J, Adachi S, Okayama T, Yoshida N, Uchiyama K, Takagi T, Handa O, Konishi H, Wakabayashi N, Yagi N, Tanigawa M, Uno K, Naito Y, Yoshikawa T
- Organizer
  101st American Association for Cancer Research(AACR)
- Place of Presentation
  Washington, DC, USA
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-21590770
[Presentation] Hyperthermia enhances the anti-tumor activity of adoptive transfer of naive T cells2010
- Author(s)
  Matsumoto T, Kokura S, Ishikawa T, Funaki J, Adachi S, Okayama T, Yoshida N, Sakamoto N, Uchiyama K, Takagi T, Handa O, Konishi H, Wakabayashi N, Yagi N, Naito Y, Kato A, Tomita K, Enoki T, Yoshikawa T
- Organizer
  101st American Association for Cancer Research(AACR)
- Place of Presentation
  Washington, DC, USA
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-21590770
[Presentation] The role of BACH1 in Dextran Sodium Sulfate (DSS)-Induced Colitis in Mice2010
- Author(s)
  Takagi T, Naito Y, Harusato A, Yamada S, Fukumoto K, Inoue K, Horie R, Mizushima K, Omatsu T, Hirata I, Yoshida N, Uchiyama K, Uchiyama K, Ishikawa T, Handa O, Konishi H, Wakabayashi N, Yagi N, Kokura S, Ichikawa H, Muto A, Igarashi K, Yoshikawa T
- Organizer
  The 111th Annual Meeting of the AGA Institute. Digestive Disease Week
- Place of Presentation
  New Orleans, USA.
- Year and Date
  2010-05-02
- Data Source
  KAKENHI-PROJECT-22590706
[Presentation] ビタミンEによるメチルパラベン/紫外線惹起性ケラチノサイト細胞毒性軽減2007
- Author(s)
  半田修
- Organizer
  第18回ビタミンE研究会
- Place of Presentation
  長崎
- Year and Date
  2007-01-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18510062
[Presentation] UV potentiates cytotoxicity of additives in cosmetics on human skin keratinocytes2007
- Author(s)
  Osamu, Handa, Satoshi, Kokura, Katsura, Mizushima, Satomi, Akagiri, Tomohisa, Takagi, Yuji, Naito, Norimasa, Yoshida, Toshikazu, Yoshikawa
- Organizer
  8th World Congress on Inflammation
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2007-06-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18510062
[Presentation] UV potentiates cytotoxicity of additives in cosmetics on human skin keratinocytes2007
- Author(s)
  Osamu Handa
- Organizer
  8th World Congresson Inflammation
- Place of Presentation
  Copenhagen,Denmark.
- Year and Date
  2007-06-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18510062
[Presentation] UV potentiates cytotoxicity of additives in cosmetics on human skin keratinocytes.2007
- Author(s)
  半田修
- Organizer
  8th World Congress on Inflammation.
- Place of Presentation
  Copenhagen, Denmark.
- Year and Date
  2007-06-19
- Data Source
  KAKENHI-PROJECT-18510062
[Presentation] Vitamin E ameliorates methylparaben/ultraviolet-induced cytotoxicity on skin keratinocytes2007
- Author(s)
  Osamu, Handa, Satoshi, Kokura, Satomi, Akagiri, Tomohisa, Takagi, Yuji, Naito, Norimasa, Yoshida, Toshikazu, Yoshikawa
- Organizer
  18th annual meeting of Japanese society of vitamin E research
- Place of Presentation
  Nagasaki, Japan
- Year and Date
  2007-01-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18510062
[Presentation] 紫外線照射下での化粧品添加物の皮膚ケラチノサイトに対する毒性発現の検討2006
- Author(s)
  半田修
- Organizer
  日本過酸化脂質・フリーラジカル学会第30回大会
- Place of Presentation
  東京
- Year and Date
  2006-10-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18510062
[Presentation] Effect of whole body hyperthermia for the early stage of rheumatoid arthritis-2006
- Author(s)
  Inoue, M., Kokura, S., Nakabe, N., Takagi, T., Mizushima, K., Adachi, S., Handa, O., Manabe, E., Naito, Y., Yoshida, N., Yoshikawa, T
- Organizer
  The 4th Asian Congress of Hyperthermic Oncology &The 23rd Japanese Congress of Hyperthermic Oncology
- Place of Presentation
  Nara
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500417
[Presentation] Cytotoxic effect of cosmetic additives on ultraviolet exposed Skin keratinocytes2006
- Author(s)
  Osamu, Handa, Satoshi, Kokura, Katsura, Mizushima, Tomohisa, Takagi, Hiroshi, Ichikawa, Yuji, Naito, Toru, Tanigawa, Norimasa, Yoshida, Toshikazu, Yoshikawa
- Organizer
  30th annual meeting of Japanese Society for Lipid peroxidation and Free Radical Research
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2006-10-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18510062
[Presentation] Effect of Whole body hyperthermia for the early stage of rheumatoid arthritis in animal model2006
- Author(s)
  Inoue, M., Kokura, S., Nakabe, N., Takagi, T., Mizushima, K., Adachi, S., Handa O., Manabe, E., Naito, Y., Yoshikawa, T
- Organizer
  12th Congress of the Asia Pacific league of associations for rheumatology
- Place of Presentation
  Kuala Lumpur, Malaysia
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500417

1. NAITO Yuji (00305575)

# of Collaborated Projects: 8 results

# of Collaborated Products: 46 results
2. TAKAGI Tomohisa (70405257)

# of Collaborated Projects: 5 results

# of Collaborated Products: 28 results
3. KOKURA Satoshi (80347442)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
4. YOSHIKWA Toshikazu (90158410)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
5. YOSHIDA Norimasa (30166962)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
6. ISHIKAWA Takeshi (90372846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
7. Fukui Akifumi (60725307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 水島かつら (20564115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 木下健司 (70441219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 内山和彦 (50298428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. 吉田直久 (50340089)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 東村泰希 (70628924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 塩谷昭子 (80275354)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. 井上亮 (70443926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. MINAMIYAMA Yukiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. ICHIKAWA Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 堅田和弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 伊藤友子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
19. 小西英幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Handa Osamu 半田 修

半田 修 ハンダ オサム

HANDA Osamu 半田 修

Research Projects

Research Products

Co-Researchers

Crohn病の腸内細菌叢と局所サイトカインに基づく生物学的製剤の選択基準の確立Principal Investigator

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Analysis of endoscopic brush samples identified mucosa associated dysbiosis and the expression of tight junction protein in functional dyspepsia.

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Precision Medicine for Colon Cancer by High-throughput Analysis by Quantitative Mass Spectrometry

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Development of practical method for the diagnosis of infection and antibiotics susceptibility of H. pyloriPrincipal Investigator

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The effect of carbon monoxide in the intestinal inflammation

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Development of hyperthermicimmunetherapy for cancer

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Hyperthermic treatment for early stage of rheumatoid arthritis

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Prediction of the cytotoxicity of additives in cosmetics on UV-exposed human skin keratinocytesPrincipal Investigator

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[Book] 日本がん予防学会. NEWS LETTER.「高校生対象のピロリ発癌撲滅計画」 No86. 20152015

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[Journal Article] Reduced abundance of butyric acid-producing bacteria in the ileal mucosa-associated microbiota of ulcerative colitis patients2023

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[Journal Article] Serial Changes in Intestinal Stenotic Stiffness in Patients with Crohn’s Disease Treated with Biologics: A Pilot Study Using Ultrasound Shear Wave Elastography2023

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[Journal Article] Reduction of butyric acid-producing bacteria in the ileal mucosa-associated microbiota is associated with the history of abdominal surgery in patients with Crohn’s disease2023

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[Journal Article] Higher Levels of Streptococcus in Upper Gastrointestinal Mucosa Associated with Symptoms in Patients with Functional Dyspepsia.2020

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Handa Osamu 半田修

半田修ハンダオサム

HANDA Osamu 半田修