MANABE Takayuki 眞部孝幸

… Alternative Names

眞部孝幸マナベタカユキ

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Researcher Number	90382283
Other IDs
Affiliation (Current)	2025: 中京学院大学, 看護学部, 教授
Affiliation (based on the past Project Information) *help	2015 – 2017: 中京学院大学, 看護学部, 教授 2012 – 2014: 藤田保健衛生大学, 総合医科学研究所, 准教授 2009 – 2010: Fujita Health University, 総合医科学研究所, 講師 2007: The Institute of Physical and Chemical Research, 神経分化・再生研究チーム, 研究員 2007: Fujita Health Science University, School of Medicine, Assistant Professor 2006: 奈良県立医大, 医学部, 助手 2004 – 2006: 奈良県立医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / Nerve anatomy/Neuropathology / Nerve anatomy/Neuropathology / Biological Sciences / General anatomy (including Histology/Embryology) Except Principal Investigator Neurochemistry/Neuropharmacology / Psychiatric science / Biological Sciences
Keywords	Principal Investigator 統合失調症 / hnRNPA1 / オリゴデンドロサイト / スプライシング / 精神疾患 / alternative splicing / oligodendrocyte / hnRNAA1 / 選択的スプライシング / 神経発生・分化・異常 … More / スクリーニング / リンパ芽球 / GABA / ES / アセチルコリン / 神経分化 / Lhx8 / L3 … More Except Principal Investigator CREB / Astrocyte / Unfolded nrotein resnonse / ER stress / Transcription factor / ATF family / ノックアウトマウス / ATF ファミリー / 細胞死 / シャペロン / 脳損傷 / アストロサイト / 小胞体ストレス / 転写調節因子 / hnRNP C1/C2 / オリゴデンドロサイト / 統合失調症 / 国際情報交換 / 神経科学 / cell line / hnRNPC / schizophrenia / oligodendrocyte / 分化 / GABA / アセチルコリン / ノックダウン / siRNA / Lhx8 / L3 Less

Elucidation of the mechanism of onset of schizophrenia caused by aberrant splicing and development of novel RNA medicinePrincipal Investigator
- Principal Investigator
  
  Manabe Takayuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Chukyo Gakuin University
Schizophrenia and oligodendrocyte; roles of hnRNPC1 and 2
- Principal Investigator
  
  Iwata Keiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  University of Fukui
hnRNPA1 as a new neural cell differentiation development regulator -Aim at psychiatric disorder medical treatment-Principal Investigator
- Principal Investigator
  
  MANABE Takayuki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Fujita Health University
統合失調症における髄鞘の分化・発達異常と選択的スプライシング因子hnRNPA1Principal Investigator
- Principal Investigator
  
  眞部孝幸
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Fujita Health University
Search for an aberrant splicing associated with schizophrenia specific antigenPrincipal Investigator
- Principal Investigator
  
  MANABE Takayuki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Fujita Health University
Functional analysiss of OASIS, a glia-specific ER stress sensax protein.
- Principal Investigator
  
  WANAKA Akio
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Nara Medical University
前脳基底部アセチルコリン神経とLhxファミリー-分子メカニズムの解明とその応用-Principal Investigator
- Principal Investigator
  
  眞部孝幸
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  The Institute of Physical and Chemical Research
  Nara Medical University
前脳基底部コリン作動性神経特異的コンディショナルノックアウトマウスの作成と解析
- Principal Investigator
  
  WANAKA Akio
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Medical University

All 2017 2016 2015 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book Other

[Book] Methods Mol.Biol.2010
- Author(s)
  Manabe T., Wanaka A.
- Publisher
  Regulation and/or Repression of Cholinergic Differentiation of Murine Embryonic Stem Cells using RNAi Against Transcription Factor L3/Lhx8(印刷中)
- Data Source
  KAKENHI-PROJECT-21700385
[Book] Methods Mol.Biol.2010
- Author(s)
  Manabe T., Wanaka A.
- Publisher
  Regulation and/or Repression of Cholinergic Differentiation of Murine Embryonic Stem Cells using RNAi Against Transcription Factor L3/Lhx8(印刷中)
- Data Source
  KAKENHI-PUBLICLY-21112519
[Book] Protein, Nucleic Acid, Enzyme.2009
- Author(s)
  Mayeda A., Manabe T., Ohe K.
- Total Pages
  6
- Publisher
  Oncogenic HMGA1a protein causes Sporadic Alzheimer's disease-associated aberrant splicing : The molecular mechanism reveals a link with U1 snRNP-mediated gene repression system
- Data Source
  KAKENHI-PUBLICLY-21112519
[Book] Protein, Nucleic Acid, Enzyme.2009
- Author(s)
  Mayeda A., Manabe T., Ohe K.
- Total Pages
  6
- Publisher
  Oncogenic HMGA1a protein causes Sporadic Alzheimer's disease-associated aberrant splicing : The molecular mechanism reveals a link with U1 snRNP-mediated gene repression system
- Data Source
  KAKENHI-PROJECT-21700385
[Journal Article] MU314, a novel selective estrogen receptor modulator (SERM), improves estrogen-dependent depressive behaviors.2017
- Author(s)
  Izumo N, Ishibashi Y, Ono Y, Toho M, Sumino A, Kameyama T, Morikawa T, Shiba Y, Watanabe Y, Manabe T.
- Journal Title
  
  Global Drugs and Therapeutics.
  
  Volume: 2 Pages: 1-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06787
[Journal Article] Regulation and/or Repression of Cholinergic Differentiation of Murine Embryonic Stem Cells using RNAi Against Transcription Factor L3/Lhx8.2017
- Author(s)
  Manabe T. and Wanaka A.
- Journal Title
  
  Methods in Mol. Biol.
  
  Volume: 1622 Pages: 101-109
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06787
[Journal Article] Potentiation of nerve growth factor-induced neurite outgrowth by a novel SERM, MU314, in PC12 cells.2017
- Author(s)
  Izumo N, Ono Y, Inatomi C, Toho M, Katoh S, Tsuzuki S, Manabe T, Watanabe Y.
- Journal Title
  
  Pharmacometrics.
  
  Volume: 92 Pages: 45-52
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06787
[Journal Article] Fluvoxamine reverses estrogen-dependent decline in voluntary activities and decreased amygdala levels of serotonin in ovariectomized rats2016
- Author(s)
  Yukiko Ishibashia, Nobuo Izumoc, Keiko Iwata, Tomomi Morikawa, Toshiki Kameyama, Yasuo Watanabe, Takayuki Manabee and Hideo Matsuzaki
- Journal Title
  
  Journal of Brain Science
  
  Volume: -
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06787
[Journal Article] Fluvoxamine reverses estrogen-dependent decline in voluntary activities and decreased amygdala levels of serotonin in ovariectomized rats.2016
- Author(s)
  Ishibashi Y, Izumo N, Iwata K, Morikawa T, Kameyama T, Watanabe Y, Manabe T Matsuzaki H.
- Journal Title
  
  Journal of Brain Science
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461756
[Journal Article] Fluvoxamine reverses estrogen-dependent decline in voluntary activities and decreased amygdala levels of serotonin in ovariectomized rats.2016
- Author(s)
  Ishibashia Y, Izumoc N, Iwata K, Morikawa T, Kameyama T, Watanabe Y, *Manabe T and *Matsuzaki M.
- Journal Title
  
  J. Brain Sci.
  
  Volume: 46 Pages: 5-9
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06787
[Journal Article] The human oligodendrocyte proteome.2013
- Author(s)
  Iwata K, Café-Mendes CC, Schmitt A, Steiner J, Manabe T, Matsuzaki H, Falkai P, Turck CW, Martins-de-
- Journal Title
  
  Proteomis
  
  Volume: 13 Issue: 23-24 Pages: 3548-3663
- DOI
  10.1002/pmic.201300201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700358, KAKENHI-PROJECT-25461756
[Journal Article] 統合失調症における選択的スプライシング調節の破綻2013
- Author(s)
  眞部孝幸,森川智美
- Journal Title
  
  藤田学園医学会誌
  
  Volume: 37 Pages: 15-20
- Data Source
  KAKENHI-PROJECT-24700358
[Journal Article] 統合失調症における選択的スプライシング調節の破綻2013
- Author(s)
  眞部孝幸、森川智美
- Journal Title
  
  藤田学園医学会誌
  
  Volume: 37巻 Pages: 15-20
- Data Source
  KAKENHI-PROJECT-24700358
[Journal Article] Triggers for Autism: genetic and environmental factors2012
- Author(s)
  Matsuzaki H, Iwata K, Manabe T, Mori N
- Journal Title
  
  Journal of Central Nervous System Disease
  
  Volume: 4 Pages: 1-10
- DOI
  10.4137/jcnsd.s9058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200014, KAKENHI-PROJECT-24700358
[Journal Article] Vldlr overexpression causes hyperactivity in rats.2012
- Author(s)
  Iwata K
- Journal Title
  
  Mol Autism.
  
  Volume: 3 Issue: 1 Pages: 11-11
- DOI
  10.1186/2040-2392-3-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591258, KAKENHI-PROJECT-22591260, KAKENHI-PROJECT-23390288, KAKENHI-PROJECT-23659560, KAKENHI-PROJECT-23659561, KAKENHI-PROJECT-23791322, KAKENHI-PROJECT-24591702, KAKENHI-PROJECT-24700358
[Journal Article] Decreased voluntary activity and amygdala levels of serotonin and dopamine in ovariectomized rats2012
- Author(s)
  Izumo N, Ishibashi Y, Ohba M, Morikawa T and Manabe T.
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 227巻 Issue: 1 Pages: 1-6
- DOI
  10.1016/j.bbr.2011.10.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700358
[Journal Article] Trans-mesenteric neural crest cells are the principal source of the colonic enteric nervous system.2012
- Author(s)
  Nishiyama, C., Uesaka, T., Manabe, T., Yonekura, Y., Nagasawa, T., Newgreen, D.F., Young, H.M., *Enomoto, H.
- Journal Title
  
  Nat. Neurosci.
  
  Volume: 15(9) Issue: 9 Pages: 1211-1218
- DOI
  10.1038/nn.3184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390096, KAKENHI-PUBLICLY-23111536, KAKENHI-PROJECT-24700358, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111003
[Journal Article] Altering the expression balance of hnRNP C1 and C2 changes the expression of myelination-ewlated genes.2011
- Author(s)
  Iwata K., Matsuzaki H., Manabe T., Mori N.
- Journal Title
  
  Psychiat.Res. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700385
[Journal Article] Transient activation of Notch signaling in the injured adult brain2010
- Author(s)
  Tatsumi K., Okuda H., Makinodan M., Yamauchi T., Makinodan E., Matsuyoshi H., Manabe T., Wanaka A.
- Journal Title
  
  J.Chem.Neuroanat. 39
  
  Pages: 15-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700385
[Journal Article] Aberrant regulation of alternative pre-mRNA splicing in Schizophrenia2010
- Author(s)
  Morikawa T., Manabe T.
- Journal Title
  
  Neurochemistry International
  
  Volume: 57 Pages: 691-704
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21112519
[Journal Article] The expression of HMGA1a is increased in lymphoblastoid cell lines from Schizophrenia patients2010
- Author(s)
  Morikawa T., Manabe T., Ito Y., Yamada S., Yoshimi A., Nagai T., Ozaki N., Mayeda A.
- Journal Title
  
  Neurochem.Int. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700385
[Journal Article] Animal models of autism : an epigenetic and environmental viewpoint.2010
- Author(s)
  Iwata K., Matsuzaki H., Takei N., Manabe T., Mori N.
- Journal Title
  
  Journal of Central Nervous System Disease 2
  
  Pages: 37-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700385
[Journal Article] The expression of HMGA1a is increased in lymphoblastoid cell lines from Schizophrenia patients.2010
- Author(s)
  Morikawa T., Manabe T., Ito Y., Yamada S., Yoshimi A., Nagai T., Ozaki N., Mayeda A.
- Journal Title
  
  Neurochem.Int. 56
  
  Pages: 736-739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700385
[Journal Article] The expression of HMGA1a is increased in lymphoblastoid cell lines from Schizophrenia patients2010
- Author(s)
  Morikawa T., Manabe T., Ito Y., Yamada S., Yoshimi A., Nagai T., Ozaki N., Mayeda A.
- Journal Title
  
  Neurochem Int. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21112519
[Journal Article] Animal models of autism : an epigenetic and environmental view point.2010
- Author(s)
  Iwata K., Matsuzaki S., Takei N, Manabe T., Mori N.
- Journal Title
  
  Journal of Central Nervouse System Disease
  
  Volume: 2 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700385
[Journal Article] Transient activation of Notch signaling in the injured adult brain.2010
- Author(s)
  Tatsumi K., Okuda H., Makinodan M., Yamauchi T., Makinodan E., Matsuyoshi H., Manabe T., Wanaka A.
- Journal Title
  
  J.Chem.Neuroanat. 39
  
  Pages: 15-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700385
[Journal Article] Aberrant regulation of alternative splicing in Schizophrenia.2010
- Author(s)
  Morikawa T., Manabe T.
- Journal Title
  
  Neurochem.Int. 57
  
  Pages: 691-704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700385
[Journal Article] Transient activation of Notch signaling in the injured adult brain2010
- Author(s)
  Tatsumi K., Okuda H., Makinodan M., Yamauchi T., Makinodan E., Natsuyoshi H., Manabe T., Wanaka A.
- Journal Title
  
  J.Chem.Neuroanat. 39
  
  Pages: 15-19
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21112519
[Journal Article] Animal models of autism : an epigenetic and environmental view point.2010
- Author(s)
  Iwata K., Matsuzaki S., Takei N, Manabe T., Mori N.
- Journal Title
  
  Journal of Central Nervouse System Disease
  
  Volume: 2 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21112519
[Journal Article] Aberrant regulation of alternative pre-mRNA splicing in Schizophrenia2010
- Author(s)
  Morikawa T., Manabe T.
- Journal Title
  
  Neurochemistry International
  
  Volume: 57 Pages: 691-704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700385
[Journal Article] Regulation and/or Repression of Cholinergic Differentiation of Murine Embryonic Stem Cells using RNAi Against Transcription Factor L3/Lhx8.2010
- Author(s)
  Manabe T., Wanaka A.
- Journal Title
  
  Methods Mol.Biol. 650
  
  Pages: 101-109
- Data Source
  KAKENHI-PROJECT-21700385
[Journal Article] Oncogenic HMGA1a protein causes Sporadic Alzheimer's disease-associated aberrant splicing : The molecular mechanism reveals a link with U1 snRNP-mediated gene repression system.2009
- Author(s)
  Mayeda A., Manabe T., Ohe K.
- Journal Title
  
  Protein, Nucleic Acid, Enzyme. 54
  
  Pages: 2245-2250
- Data Source
  KAKENHI-PROJECT-21700385
[Journal Article] The HMGA1a recognition candidate DNA sequences inhuman2009
- Author(s)
  Manabe T., Katayama T., Tohyama M.
- Journal Title
  
  PLoS One. 4
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21112519
[Journal Article] The HMGA1a recognition candidate DNA sequences inhuman2009
- Author(s)
  Manabe T., Katayama T., Tohyama M.
- Journal Title
  
  PLoS One. 4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700385
[Journal Article] The HMGA1a recognition candidate DNA sequencesin human.2009
- Author(s)
  Manabe T., Katayama T., Tohyama M.
- Journal Title
  
  PLoS One 4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700385
[Journal Article] Knockdown of the L3/Lhx8 gene suppresses cholinergic differentiation of murine embryonic stem cell-derived spheres.2008
- Author(s)
  Manabe, T., K.Tatsumi, et. al.
- Journal Title
  
  Int J Dev Neurosci. 26
  
  Pages: 249-252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500298
[Journal Article] Knockdown of the L3/Lhx8 gene suppresses cholinergic differentiation of murine embryonic stem cell-derived spheres2008
- Author(s)
  Manabe T., et. al.
- Journal Title
  
  Int J Dev Neurosci 26
  
  Pages: 249-252
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500298
[Journal Article] Maternal immune activation in mice delays myelination and axonal development in the hippocampus of the offspring.2008
- Author(s)
  Makinodan M., Tatsumi K., Manabe T., Yamauchi T., Makinodan E., Matsuyoshi H., Shimoda S., Noriyama Y., Kishimoto T. and Wanaka A.
- Journal Title
  
  J. Neurosci. Res. In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17790143
[Journal Article] Knockdown of the L3/Lhx8 gene suppresses cholinergic differentiation of murine embryonic stem cel -derived spheres2008
- Author(s)
  Manabe, T., K., Tatsumi, et. al.
- Journal Title
  
  Int J Dev Neurosci 26(2)
  
  Pages: 249-252
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500298
[Journal Article] Knockdown of the L3/Lhx8 gene suppresses cholinergic differentiation of murine embryonic stem cell-derived spheres.2008
- Author(s)
  Manabe T, Tatsumi K, Inoue M, Matsuyoshi H, Makinodan M, Yamauchi T, Makinodan E, Yokoyama S, Sakumura R, Okuda H, Wanaka A.
- Journal Title
  
  Int J Dev Neurosci. 26
  
  Pages: 249-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17790143
[Journal Article] L3/Lhx8 is a pivotal factor for cholinergic differentiation of murine embryonic stem cells2007
- Author(s)
  Manabe, T., K., Tatsumi, et. al.
- Journal Title
  
  Cell Death Differ 14
  
  Pages: 1080-1085
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500298
[Journal Article] A novel role for Fyn: change in sphere formation ability in murine embryonic stem cells2007
- Author(s)
  Makinodan E, Manabe T, Makinodan M, Yamauchi T, Matsuyoshi H, Sakumura R, Tatsumi K, Wanaka A.
- Journal Title
  
  Neuroscience. 147
  
  Pages: 1-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17790143
[Journal Article] L3/Lhx8 is a pivotal factor for cholinergic differentiation of murine embryonic stem cells.2007
- Author(s)
  Manabe T, Tatsumi K, Inoue M, Makinodan M, Yamauchi T, Makinodan E, Yokoyama S, Sakumura R, Wanaka A.
- Journal Title
  
  Cell Death Differ. 14
  
  Pages: 1080-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17790143
[Journal Article] L3/Lhx8 is a pivotal factor for cholinergic differentiation of murine emb rvonic stem cells2007
- Author(s)
  Manabe T., et. al.
- Journal Title
  
  Cell Death Differ 14
  
  Pages: 1080-1085
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500298
[Journal Article] L3/Lhx8 is a pivotal factor for cholinergic differentiation of murine embryonic stem cells.2007
- Author(s)
  Manabe T. et al.
- Journal Title
  
  Cell Death Differ. (印刷中)
- Data Source
  KAKENHI-PROJECT-18500298
[Journal Article] DACS, novel matrix structure composed of chondroitin sulfate proteoglycan in the brain.2007
- Author(s)
  Hayashi N, Tatsumi K, Okuda H, Yoshikawa M, Ishizaka S, Miyata S, Manabe T, Wanaka A.
- Journal Title
  
  Biochem Biophys Res Commun. 364
  
  Pages: 410-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17790143
[Journal Article] L3/Lhx8 is a pivotal factor for cholinergic differentiation of murine embryonic stem cells.2007
- Author(s)
  Manabe, T., K.Tatsumi, et. al.
- Journal Title
  
  Cell Death Differ 14
  
  Pages: 1080-1085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500298
[Journal Article] A novel role for Fyn : change in sphere formation ability in murine embryonic stem cells2007
- Author(s)
  Makinodan, E., T., Manabe, et. al.
- Journal Title
  
  Neuroscience 147(1)
  
  Pages: 1-4
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500298
[Journal Article] Novel interaction between HMGA1a and StIP1 in murine terminally differentiated retina2006
- Author(s)
  Okuda, H., T., Manabe, et. al.
- Journal Title
  
  Mol Cell Neurosci 33(1)
  
  Pages: 81-87
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500298
[Journal Article] L3/Lhx8 is involved in the determination of cholinergic or GABAergic cell fate.2005
- Author(s)
  Manabe T, Tatsumi K, Inoue M, Matsuyoshi H, Makinodan M, Yokoyama S, Wanaka A.
- Journal Title
  
  Journal of Neurochemistry 94(3)
  
  Pages: 723-730
- Data Source
  KAKENHI-PROJECT-17790143
[Journal Article] L3/Lhx8: an important selector gene determining whether cholinergic or UABAergic cell fates.2005
- Author(s)
  Manabe T. et al.
- Journal Title
  
  J.Neurochem. (In press)
- Data Source
  KAKENHI-PROJECT-16015296
[Presentation] グローバルなスプライシング抑制因子hnRNPA1 の発現量・発現様式の違いと神経ホメオスタシスの攪乱.2017
- Author(s)
  森川智美、眞部孝幸.
- Organizer
  日本薬学会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K06787
[Presentation] スプライシング異常から解析する精神疾患－ヒトhnRNPA1 の新規isoform とその機能－2015
- Author(s)
  眞部孝幸
- Organizer
  金沢大学と北陸先端科学技術大学院大学 RNA 研究公開合同セミナー
- Place of Presentation
  金沢大学
- Year and Date
  2015-12-11
- Invited
- Data Source
  KAKENHI-PROJECT-15K06787
[Presentation] 統合失調症患者で転写・スプライシング調節因子であるHMGA1aが上昇している意義2010
- Author(s)
  眞部孝幸、森川智美、山下祐子、前田明
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21700385
[Presentation] 統合失調症患者で転写・スプライシング調節因子であるHMGA1aが上昇している意義2010
- Author(s)
  眞部孝幸、森川智美、山下祐子、前田明
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21700385
[Presentation] 統合失調症患者で転写・スプライシング調節因子であるHMGA1aが上昇している意義2010
- Author(s)
  眞部孝幸、森川智美、山下祐子、前田明
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PUBLICLY-21112519
[Presentation] 統合失調症患者におけるhnRNP A1による異常スプライシング2009
- Author(s)
  眞部孝幸、前田明
- Organizer
  第32回分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21700385
[Presentation] 統合失調症の異常スプライシングにグローバルなスプライシング抑制因子であるhnRNP A1が関与している可能性を探る2009
- Author(s)
  眞部孝幸、前田明
- Organizer
  第11回日本RNA学会
- Place of Presentation
  新潟
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-21700385
[Presentation] 統合失調症と異常スプライシング2009
- Author(s)
  眞部孝幸、前田明
- Organizer
  第69回日本解剖学会中部支部大会
- Place of Presentation
  浜松
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-21700385
[Presentation] 統合失調症患者におけるhnRNP A1 による異常スプライシング2009
- Author(s)
  眞部孝幸、前田明
- Organizer
  第32回分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PUBLICLY-21112519
[Presentation] 腸管神経堤細胞の移動様式2009
- Author(s)
  榎本秀樹、西山千尋、眞部考幸、Heather Young、Don Newgreen.
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-21700385
[Presentation] 統合失調症の異常スプライシングにグローバルなスプライシング抑制因子であるhnRNP A1が関与している可能性を探る2009
- Author(s)
  眞部孝幸、前田明
- Organizer
  第11回日本RNA学会
- Place of Presentation
  新潟
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PUBLICLY-21112519
[Presentation] 統合失調症患者におけるhnRNP A1 による異常スプライシング2009
- Author(s)
  眞部孝幸、前田明
- Organizer
  第32回分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21700385
[Presentation] 統合失調症と異常スプライシング2009
- Author(s)
  眞部孝幸、前田明
- Organizer
  第69回日本解剖学会中部支部大会
- Place of Presentation
  浜松
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PUBLICLY-21112519
[Presentation] 腸管神経堤細胞の移動様式2009
- Author(s)
  榎本秀樹、西山千尋、眞部考幸, Heather Young、Don Newgreen
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PUBLICLY-21112519
[Presentation] Alteration of the expression balance of hnRNP C1 and C2 changes the expression of myelination- and schizophrenia-related genes in the human oligodendrocytic cell line.
- Author(s)
  Iwata K, Matsuzaki H, Manabe T, Martins-de-Souza D.
- Organizer
  4rd Biennial Schizophrenia International Research Society Conference
- Place of Presentation
  Florence, Italy
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-25461756
[]

1. WANAKA Akio (90210989)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. TATSUMI Kouko (90208033)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. Iwata Keiko (30415088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. MATSUZAKI Hideo (00334970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 芳賀敏実 (20192263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MORIKAWA Tomomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 岩田泰秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 長澤丘司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MANABE Takayuki 眞部 孝幸

眞部 孝幸 マナベ タカユキ

Research Projects

Research Products

Co-Researchers

Elucidation of the mechanism of onset of schizophrenia caused by aberrant splicing and development of novel RNA medicinePrincipal Investigator

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Schizophrenia and oligodendrocyte; roles of hnRNPC1 and 2

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hnRNPA1 as a new neural cell differentiation development regulator -Aim at psychiatric disorder medical treatment-Principal Investigator

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統合失調症における髄鞘の分化・発達異常と選択的スプライシング因子hnRNPA1Principal Investigator

Principal Investigator

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Search for an aberrant splicing associated with schizophrenia specific antigenPrincipal Investigator

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Functional analysiss of OASIS, a glia-specific ER stress sensax protein.

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前脳基底部アセチルコリン神経とLhxファミリー-分子メカニズムの解明とその応用-Principal Investigator

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前脳基底部コリン作動性神経特異的コンディショナルノックアウトマウスの作成と解析

Principal Investigator

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Research Institution

[Book] Methods Mol.Biol.2010

Author(s)

Publisher

Data Source

[Book] Methods Mol.Biol.2010

Author(s)

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[Book] Protein, Nucleic Acid, Enzyme.2009

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[Book] Protein, Nucleic Acid, Enzyme.2009

Author(s)

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[Journal Article] MU314, a novel selective estrogen receptor modulator (SERM), improves estrogen-dependent depressive behaviors.2017

Author(s)

Journal Title

Data Source

[Journal Article] Regulation and/or Repression of Cholinergic Differentiation of Murine Embryonic Stem Cells using RNAi Against Transcription Factor L3/Lhx8.2017

Author(s)

Journal Title

Data Source

[Journal Article] Potentiation of nerve growth factor-induced neurite outgrowth by a novel SERM, MU314, in PC12 cells.2017

MANABE Takayuki 眞部孝幸

眞部孝幸マナベタカユキ