Okumura Akinori 奥村彰規

… Alternative Names

奥村彰規オクムラアキノリ

OKUMURA Akinori 奥村彰規

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Researcher Number	90392357
Other IDs
Affiliation (Current)	2026: 愛知医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2024: 愛知医科大学, 医学部, 講師 2023: 愛知医科大学, 医学部, 特別研究助教 2012 – 2014: 独立行政法人国立国際医療研究センター, その他部局等, その他 2011: 独立行政法人国立国際医療研究センター, 臓器障害研究部, 上級研究員 2010: 独立行政法人国立国際医療研究センター, 臓器障害研究部, 研究員 2009: Nihon University, 文理学部, 助手 2005: (財)東京都医学研究機構, 研究員
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Metabolomics / Orthopaedic surgery Except Principal Investigator Biological Sciences
Keywords	Principal Investigator LECT2 / ウイルス感染経路 / リン酸化シグナル経路 / プロテオミクス / B型肝炎ウイルス / リン酸化プロテオミクス / HBV / 肥満 / 細小血管障害 / 糖尿病 … More / 発生・分化 / 蛋白質 / 成長板軟骨 / 骨・軟骨代謝学 … More Except Principal Investigator 神経再生 / 神経変性疾患 / 神経栄養因子 / 軸索伸長 / MOCA Less

B型肝炎ウイルス感染成立に必須な肝細胞内リン酸化シグナル経路の解明Principal Investigator
- Principal Investigator
  
  奥村彰規
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Aichi Medical University
Relationship between LECT2 and diabetic microvascular complicationsPrincipal Investigator
- Principal Investigator
  
  OKUMURA Akinori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Research Institute, International Medical Center of Japan
Effects of LECT2 on chondrocyte differentiationPrincipal Investigator
- Principal Investigator
  
  OKUMURA Akinori
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Research Institute, International Medical Center of Japan
  Nihon University
MOCAによる神経細胞の形態形成および軸索伸長に関するメカニズムの解析
- Principal Investigator
  
  原田高幸
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research

All 2024 2023 2013 2009 Other

All Journal Article Presentation

[Journal Article] 増大号肝疾患　臨床検査でどう迫る? 2章　急性の肝疾患 B型肝炎ウイルスの再活性化とモニタリング2023
- Author(s)
  奥村彰規、伊藤清顕
- Journal Title
  
  臨床検査
  
  Volume: 67 Issue: 10 Pages: 1090-1093
- DOI
  10.11477/mf.1542203419
- ISSN
  0485-1420, 1882-1367
- Year and Date
  2023-10-15
- Data Source
  KAKENHI-PROJECT-23K07449, KAKENHI-PROJECT-23K24323
[Journal Article] B型肝炎の自然経過と予後2023
- Author(s)
  奥村彰規、伊藤清顕
- Journal Title
  
  ウイルス性肝炎学2023 : 最新の病態・診断・治療情報
  
  Volume: 81-増刊7 Pages: 298-303
- Data Source
  KAKENHI-PROJECT-23K07449
[Journal Article] Increased serum leukocyte cell-derived chemotaxin 2 (LECT2) levels in obesity and fatty liver2013
- Author(s)
  Okumura A, Unoki-Kubota H, Matsushita Y, Shiga T, Moriyoshi Y, Yamagoe S, Kaburagi Y
- Journal Title
  
  BioScience Trends
  
  Volume: 7 Issue: 6 Pages: 276-283
- DOI
  10.5582/bst.2013.v7.6.276
- NAID
  130003397274
- ISSN
  1881-7815, 1881-7823
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500870, KAKENHI-PROJECT-24790938
[Journal Article] Leukocyte cell-derived chemotaxin 2 is a zinc-binding protein2013
- Author(s)
  Okumura A, Suzuki T, Miyatake H, Okabe T, Hashimoto Y, Miyakawa T, Zheng H, Unoki-Kubota H, Ohno H, Dohmae N, Kaburagi Y, Miyazaki Y, Tanokura M, Yamagoe S
- Journal Title
  
  FEBS Lett
  
  Volume: 587 Issue: 5 Pages: 404-409
- DOI
  10.1016/j.febslet.2013.01.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-23500870, KAKENHI-PROJECT-23590275, KAKENHI-PROJECT-24790938, KAKENHI-PROJECT-25461370
[Journal Article] Identification and assignment of three disulfide bonds in mammalian leukocyte cell-derived chemotaxin 2 by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry2009
- Author(s)
  Akinori Okumura, Takehiro Suzuki, Naoshi Dohmae, Tomoya Okabe, Yuki Hashimoto, Katsuyoshi Nakazato, Hideaki Ohno, Yoshitsugu Miyazaki, Satoshi Yamagoe
- Journal Title
  
  BioScience Trends
  
  Volume: 3 Pages: 139-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791422
[Journal Article] Identification and assignment of three disulfide bonds in mammalian leukocyte cell-derived chemotaxin 2 by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry2009
- Author(s)
  奥村彰規
- Journal Title
  
  BioScience Trends 3巻
  
  Pages: 139-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791422
[Presentation] B型肝炎ウイルス侵入を阻害する胆汁酸誘導体INT-767のpreS1結合様式の解析2024
- Author(s)
  奥村彰規、荒井潤、伊藤清顕
- Organizer
  第9回Gastro-PLUS
- Data Source
  KAKENHI-PROJECT-23K07449
[Presentation] Development of novel anti-HBV drugs based on AI technology using bile acid derivatives to inhibit HBV and NTCP binding2024
- Author(s)
  Akinori Okumura, Kazuyoshi Ikeda, Jun Arai, Kazumasa Sakamoto, Yukiko Muraki, Sayaka Nishimura, Noriko Inden, Mariko Yokogawa, Yukiko Yamashita, Yusuke Iguchi, Hirofumi Ohashi, Koichi Watashi, Takaji Wakita, Mizuho Une, Masanori Osawa, Kiyoaki Ito
- Organizer
  2024 International HBV Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07449
[Presentation] Development of a novel anti-HBV agent using bile acid derivatives that inhibit the binding of HBV and NTCP2024
- Author(s)
  Akinori Okumura, Jun Arai, Kiyoaki Ito
- Organizer
  第60回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-23K07449
[Presentation] 胆汁アルコールとその誘導体による抗HBV作用の検討2024
- Author(s)
  奥村彰規、村木由起子、井口裕介、荒井潤、山下ユキコ、西村さやか、位田法子、宇根瑞穂、伊藤清顕
- Organizer
  第45回胆汁酸研究会
- Data Source
  KAKENHI-PROJECT-23K07449
[Presentation] The efficacy of measuring natural killer activating receptor ligands to predict the pathogenesis of MASLD2024
- Author(s)
  Jun Arai, Akinori Okumura, Satoshi Kimoto, Kazumasa Sakamoto, Tomoya Kitada, Mayu Ibusuki, Rena Kitano, Tadahisa Inoue, Yukiko Muraki, Sayaka Nishimura, Noriko Inden, Naoya Kato, Kiyoaki Ito
- Organizer
  The Liver Meeting 2024 (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07449
[Presentation] INT-767の作用機序に基づいた胆汁酸誘導体による新規抗HBV薬の開発2024
- Author(s)
  奥村彰規、荒井潤、池田和由、山下ユキコ、井口裕介、横川真梨子、梅澤一夫、宇根瑞穂、大澤匡範、伊藤清顕
- Organizer
  第110回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-23K07449
[Presentation] Efficacy of measuring natural killer-activating receptor ligands to predict the pathogenesis of metabolic dysfunction-associated steatotic liver disease2024
- Author(s)
  Jun Arai, Akinori Okumura, Satoshi Kimoto, Kazumasa Sakamoto, Tomoya Kitada, Rena Kitano, Tadahisa Inoue, Yukiko Muraki, Sayaka Nishimura, Noriko Inden, Naoya Kato, Kiyoaki Ito
- Organizer
  APASL Oncology 2024 Chiba
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07449
[Presentation] AH-337 is a novel bile acid derivative designed to inhibit HBV entry2023
- Author(s)
  Akinori Okumura, Yukiko Yamashita, Yusuke Iguchi, Mariko Yokogawa, Hirofumi Ohashi, Jun Arai, Kazuo Umezawa, Kazuyoshi Ikeda, Masanori Osawa, Koichi Watashi, Takaji Wakita, Mizuho Une, Kiyoaki Ito
- Organizer
  2023 International HBV Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07449
[Presentation] Ｂ型肝炎ウイルスに直接作用する胆汁酸誘導体による新規治療薬の開発2023
- Author(s)
  奥村彰規、横川真梨子、山下ユキコ、井口裕介、池田和由、大澤匡範、宇根瑞穂、米田政志、伊藤清顕
- Organizer
  第44回胆汁酸研究会
- Data Source
  KAKENHI-PROJECT-23K07449
[Presentation] Novel monoclonal antibody and ADAM17 enzymatic inhibitor could induce NK cell-mediated cytotoxicity in HCC by targeting NKG2D ligands2023
- Author(s)
  Jun Arai, Kazumasa Sakamoto, Akinori Okumura, Mayu Ibusuki, Rena Kitano, Satoshi Kimoto, Tadahisa Inoue, Yuji Kobayashi, Yukiomi Nakade, Naoya Kato, Kiyoaki Ito
- Organizer
  APASL Oncology 2023 Sendai
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07449
[Presentation] 胆汁酸誘導体INT-767はHBVの侵入阻害剤として機能する2023
- Author(s)
  奥村彰規、伊藤清顕
- Organizer
  第31回日本抗ウイルス療法学会
- Data Source
  KAKENHI-PROJECT-23K07449
[Presentation] 胆汁酸誘導体INT-767による抗HBV効果の分子メカニズムの解明2023
- Author(s)
  奥村彰規、荒井潤、伊藤清顕
- Organizer
  第45回日本肝臓学会西部会
- Data Source
  KAKENHI-PROJECT-23K07449
[Presentation] 血中LECT2濃度は肥満と脂肪肝の予測因子となりうるか2013
- Author(s)
  6. 奥村彰規、久保田浩之、松下由実、志賀智子、森吉百合子、鏑木康志
- Organizer
  第34回日本肥満学会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24790938
[Presentation] Leukocyte cell-derived chemotaxin 2 is a zinc-binding protein: the monomeric forms are stabilized by the zinc ion2013
- Author(s)
  5. Akinori Okumura, Takehiro Suzuki, Hideyuki Miyatake, Takuya Miyakawa, Hai Zheng, Hiroyuki Unoki-Kubota, Naoshi Dohmae, Yasushi Kaburagi, Masaru Tanokura, Satoshi Yamagoe
- Organizer
  The 36th Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  Kobe Port Island
- Data Source
  KAKENHI-PROJECT-24790938
[Presentation] Leukocyte cell-derived chemotaxin 2は新規の肥満関連因子である2013
- Author(s)
  9. 奥村彰規、久保田浩之、松下由実、志賀智子、森吉百合子、鏑木康志
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本ほか
- Data Source
  KAKENHI-PROJECT-24790938
[Presentation] ガラクトサミン/LPS肝障害モデルを用いたLECT2の機能解析2009
- Author(s)
  奥村彰規、大川原明子、山越智
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-21791422
[Presentation] 血中タンパク質LECT2の糖尿病網膜症患者における血中濃度と網膜毛細血管内皮細胞への影響
- Author(s)
  奥村彰規、久保田浩之、松下由実、本田律子、梶尾裕、野田光彦、鏑木康志
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪市
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24790938
[Presentation] Serum leukocyte cell-derived chemotaxin 2 levels are decreased in patients with diabetic retinopathy
- Author(s)
  Akinori Okumura, Hiroyuki Kubota, Yumi Matsushita, Tomoko Shiga, Ritsuko Honda, Hiroshi Kajio, Mitsuhiko Noda, Yasushi Kaburagi
- Organizer
  The 37th Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24790938

1. 原田高幸 (90345306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 行方和彦 (70392355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 中村和昭 (80392356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 田之倉優

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 宮川拓也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okumura Akinori 奥村 彰規

奥村 彰規 オクムラ アキノリ

OKUMURA Akinori 奥村 彰規

Research Projects

Research Products

Co-Researchers

B型肝炎ウイルス感染成立に必須な肝細胞内リン酸化シグナル経路の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Relationship between LECT2 and diabetic microvascular complicationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of LECT2 on chondrocyte differentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MOCAによる神経細胞の形態形成および軸索伸長に関するメカニズムの解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] 増大号 肝疾患 臨床検査でどう迫る? 2章 急性の肝疾患 B型肝炎ウイルスの再活性化とモニタリング2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Data Source

[Journal Article] B型肝炎の自然経過と予後2023

Author(s)

Journal Title

Data Source

[Journal Article] Increased serum leukocyte cell-derived chemotaxin 2 (LECT2) levels in obesity and fatty liver2013

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Leukocyte cell-derived chemotaxin 2 is a zinc-binding protein2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification and assignment of three disulfide bonds in mammalian leukocyte cell-derived chemotaxin 2 by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry2009

Author(s)

Journal Title

Data Source

[Journal Article] Identification and assignment of three disulfide bonds in mammalian leukocyte cell-derived chemotaxin 2 by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry2009

Author(s)

Journal Title

Data Source

[Presentation] B型肝炎ウイルス侵入を阻害する胆汁酸誘導体INT-767のpreS1結合様式の解析2024

Author(s)

Organizer

Data Source

[Presentation] Development of novel anti-HBV drugs based on AI technology using bile acid derivatives to inhibit HBV and NTCP binding2024

Author(s)

Organizer

Data Source

[Presentation] Development of a novel anti-HBV agent using bile acid derivatives that inhibit the binding of HBV and NTCP2024

Author(s)

Organizer

Data Source

[Presentation] 胆汁アルコールとその誘導体による抗HBV作用の検討2024

Author(s)

Organizer

Data Source

[Presentation] The efficacy of measuring natural killer activating receptor ligands to predict the pathogenesis of MASLD2024

Author(s)

Okumura Akinori 奥村彰規

奥村彰規オクムラアキノリ

OKUMURA Akinori 奥村彰規

[Journal Article] 増大号肝疾患　臨床検査でどう迫る? 2章　急性の肝疾患 B型肝炎ウイルスの再活性化とモニタリング2023