TANIGUCHI Shigeki 谷口繁生

Researcher Number	90392406
Affiliation (based on the past Project Information) *help	2008 – 2011: 大分大学, 医学部, 助教
Review Section/Research Field	Principal Investigator General pharmacology Except Principal Investigator Metabolomics
Keywords	Principal Investigator ガス性メッセンジャー / 硫化水素 / 糖尿病 / 薬理学 / 膵B細胞 / 細胞保護作用 / 生理活性物質 Except Principal Investigator シグナル伝達 / 糖尿病 / 細胞・組織 … More / 生体分子 / 薬理学 / 高血糖 / 細胞保護 / L-システムイン / 酸化ストレス / L-システィン / グルタチオン / 硫化水素 / 細胞死 / インスリン分泌 / 膵B細胞 / L-システイン Less

Hydrogen sulfide protects insulin-secreting cells from cell damage-Characterization of the cytoprotective effects and the molecular mechanisms-Principal Investigator
- Principal Investigator
  
  TANIGUCHI Shigeki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Oita University
第3のガスメッセンジャー硫化水素の誘導性産生機序とその役割の解明
- Principal Investigator
  
  仁木一郎
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Oita University
Protection of pancreatic B-cell by the sulphur-containing amino acid L-cysteine and investigation of its underlying mechanisms
- Principal Investigator
  
  NIKI Ichiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Oita University

All 2012 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] Protein phosphorylation involved in the gene expression of the hydrogen sulphide producing enzyme cystathionineγ-lyase in the pancreaticβ-cell2012
- Author(s)
  Shigeki Taniguchi, Toshihide, Kimura, Tatsuhito Umeki, 省略7名
- Journal Title
  
  Molecular and Cellular Endocrinology
  
  Volume: 350 Pages: 31-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790255
[Journal Article] Protein phosphorylation involved in the gene expression of the hydrogen sulphide producing enzyme cystathionine γ-lyase in the pancreatic β-cell2012
- Author(s)
  Taniguchi S, Kimura T, Umeki T, Kimura Y, Kimura H, Ishii I, Itoh N, Naito Y, Yamamoto H, Niki I
- Journal Title
  
  Mol.Cell.Endocrinol.
  
  Volume: 350 Issue: 1 Pages: 31-38
- DOI
  10.1016/j.mce.2011.11.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591146, KAKENHI-PROJECT-22590258, KAKENHI-PROJECT-22590292, KAKENHI-PROJECT-22790255, KAKENHI-PROJECT-23500451, KAKENHI-PROJECT-23659089, KAKENHI-PROJECT-23791039, KAKENHI-PUBLICLY-23117716
[Journal Article] Significance of hydrogen sulfide production in the pancreatic β-cell2011
- Author(s)
  Shigeki Taniguchi, Ichiro Niki
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 116 Pages: 1-5
- NAID
  10029893605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790255
[Journal Article] Significance of hydrogen sulfide production in the pancreatic beta cell2011
- Author(s)
  Taniguchi S, Niki I
- Journal Title
  
  J.Pharmacol.Sci
  
  Volume: (in print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591146
[Journal Article] Significance of hydrogen sulfide production in the pancreaticβ-cell2011
- Author(s)
  Shigeki Taniguchi, Ichiro Niki
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 116 Pages: 1-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790255
[Journal Article] Hydrogen sulphide protects mouse pancreatic β-cells from cell death induced by oxidative stress, but not by endoplasmic reticulum stress2011
- Author(s)
  Shigeki Taniguchi, Lin Kang, Toshihide Kimura, Ichiro Niki
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: VOL.162 Pages: 1171-1178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790255
[Journal Article] Hydrogen sulphide protects mouse pancreaticβ-cells from cell death induced by oxidative stress, but not by endoplasmic reticulum stress2011
- Author(s)
  Shigeki Taniguchi, Lin Kang, Toshihide Kimura, 省略1名
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: 162 Pages: 1171-1178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790255
[Journal Article] Hydrogen sulphide protects mouse pancreatic β-cells from cell death induced by oxidative stress, but not by endoplasmic reticulum stress2011
- Author(s)
  Taniguchi S, Kang L, Kimura T, Niki I
- Journal Title
  
  Brit.J.Pharmacol
  
  Volume: 162 Pages: 1171-1178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591146
[Journal Article] Significance of Hydrogen Sulfide Production in the Pancreatic .BETA.-Cell2011
- Author(s)
  Taniguchi S, Niki I
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 116 Issue: 1 Pages: 1-5
- DOI
  10.1254/jphs.11R01CP
- NAID
  10029893605
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591146
[Journal Article] Actin assembly controlled by GDP-Rab27a is essential for endocytosis of the insulin secretory membrane.2010
- Author(s)
  Kimura T, Taniguchi S, Niki I
- Journal Title
  
  Arch.Biochem.Biophys
  
  Volume: 496 Pages: 33-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591146
[Journal Article] Glucose-induced translocation of coronin 3 regulates the retrograde transport of the secretory membrane in the pancreatic β-cells2010
- Author(s)
  Kimura T, Taniguchi S, Toya K, Niki I
- Journal Title
  
  Biochem.Biophys.Res.Commun
  
  Volume: 395 Pages: 318-323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591146
[Journal Article] Actin assembly controlled by GDP-Rab27a is essential for endocytosis of the insulin secretory membrane2010
- Author(s)
  Kimura T, Taniguchi S, Niki I
- Journal Title
  
  Archives of Biochemistry and Biophysics 496
  
  Pages: 33-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591146
[Journal Article] Glucose-induced production of hydrogen sulfide may protect the pancreatic beta-cells from apoptotic cell death by high glucose2009
- Author(s)
  Kaneko Y, Kimura T, Taniguchi S, Souma M, Kojima Y, Kimura Y, Kimura H, Niki I
- Journal Title
  
  FEBS Lett. 583
  
  Pages: 377-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591060
[Journal Article] Glucose-induced production of hydrogen sulfide may protect the pancreatic beta-cells from apoptotic cell death by high glucose2009
- Author(s)
  Kaneko Y, Kimura T, Taniguchi S, Souma M, Kojima Y, Kimura Y, Kimura H, Niki I
- Journal Title
  
  FEBS Letters 583
  
  Pages: 377-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] マウス膵β細胞における硫化水素産生酵素のカルシウム依存性発現調節2012
- Author(s)
  谷口繁生、木村俊秀、岡本光弘、仁木一郎
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都府京都市
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] マウス膵β細胞における硫化水素産生酵素のカルシウム依存性発現調節2012
- Author(s)
  谷口繁生
- Organizer
  第85回日本薬理学会
- Place of Presentation
  京都府京都市
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-22790255
[Presentation] Rab27aとcoronin3の細胞内局在を規定する新規GDP依存性Rab27aエフェクターの同定2012
- Author(s)
  木村俊秀、山岡真美、谷口繁生、仁木一郎
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都府京都市
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] マウス膵β細胞における硫化水素産生酵素のカルシウム依存性発現調節2012
- Author(s)
  谷口繁生、木村俊秀、岡本光弘、仁木一郎
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都府京都市
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-22790255
[Presentation] 酸化ストレス抑制により硫化水素はマウス膵β細胞を保護する2011
- Author(s)
  谷口繁生
- Organizer
  日本薬理学会
- Place of Presentation
  パシフィコ横浜(神奈川県)(学会中止により誌上発表)
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-22790255
[Presentation] 硫化水素が膵B細胞を保護する分子機序の検討2011
- Author(s)
  谷口繁生、康林、木村俊秀、仁木一郎
- Organizer
  第54回日本糖尿病学会
- Place of Presentation
  北海道札幌市
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] GDP型Rab27aエフェクターによる分子クラスターの形成とエンドサイトーシスの制御2011
- Author(s)
  木村俊秀、山岡真美、谷口繁生、仁木一郎
- Organizer
  第64回日本薬理学会西南部会
- Place of Presentation
  福岡県福岡市
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] 硫化水素が膵B細胞を保護する分子機序の検討2011
- Author(s)
  谷口繁生
- Organizer
  第54回日本糖尿病学会
- Place of Presentation
  北海道札幌市
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-22790255
[Presentation] Rab27a-GAP新規結合タンパク質の探索2011
- Author(s)
  山岡真美、木村俊秀、谷口繁生、仁木一郎
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] インスリン顆粒膜のエンドサイトーシスを調節するGDP型Rab27aエフェクターによる分子クラスターの形成2011
- Author(s)
  木村俊秀、山岡真美、谷口繁生、仁木一郎
- Organizer
  第54回日本糖尿病学会
- Place of Presentation
  北海道札幌市
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] 酸化ストレス抑制により硫化水素はマウス膵β細胞を保護する2011
- Author(s)
  谷口繁生
- Organizer
  第84回日本薬理学会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-22790255
[Presentation] GDP型Rab27a結合タンパク質coronin3の細胞内局在を制御する機構の解析2011
- Author(s)
  木村俊秀、山岡真美、谷口繁生、仁木一郎
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] 膵島における硫化水素産生酵素の発現調節の種差について2011
- Author(s)
  谷口繁生、木村俊秀、岡本光弘、仁木一郎
- Organizer
  第64回日本薬理学会西南部会
- Place of Presentation
  福岡県福岡市
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] 膵島における硫化水素産生酵素の発現調節の種差について2011
- Author(s)
  谷口繁生
- Organizer
  第64回日本薬理学会西南部会
- Place of Presentation
  福岡県福岡市
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-22790255
[Presentation] GDP型Rab27a結合タンパク質 coronin 3によるインスリン顆粒膜のエンドサイトーシス制御機構の解析2010
- Author(s)
  木村俊秀, 谷口繁生, 仁木一郎
- Organizer
  第83回日本薬理学会
- Place of Presentation
  大阪
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] マウス膵B細胞に対する硫化水素の保護作用2010
- Author(s)
  谷口繁生, 康林, 木村俊秀, 仁木一郎
- Organizer
  第83回日本薬理学会
- Place of Presentation
  大阪
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] Molecular mechanism of secretory membrane endocytosis by the GDP-dependent Rab27a effector coronin 32010
- Author(s)
  Kimura T, Taniguchi S, Niki I
- Organizer
  Asia Islet Biology and Incretin Symposium
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-08-01
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] 硫化水素によるマウス膵β細胞保護作用の特性について2010
- Author(s)
  谷口繁生
- Organizer
  第53回日本糖尿病学会
- Place of Presentation
  岡山県岡山市
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-22790255
[Presentation] アクチン骨格の制御を介したインスリン顆粒膜のリサイクリング2010
- Author(s)
  木村俊秀、谷口繁生、仁木一郎
- Organizer
  第53回日本糖尿病学会
- Place of Presentation
  岡山
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] 硫化水素によるマウス膵β細胞保護作用の特性について2010
- Author(s)
  谷口繁生
- Organizer
  日本糖尿病学会
- Place of Presentation
  岡山市デジタルミュージアム(岡山県)
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-22790255
[Presentation] 硫化水素によるマウス膵B細胞保護作用の特性について2010
- Author(s)
  谷口繁生、康林、木村俊秀、仁木一郎
- Organizer
  第53回日本糖尿病学会
- Place of Presentation
  岡山
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] 硫化水素による細胞ストレス抑制と膵B細胞保護2009
- Author(s)
  谷口繁生, 康林, 木村俊秀, 仁木一郎
- Organizer
  第62回日本薬理学会西南部会
- Place of Presentation
  愛媛
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] Roles of the GDP-dependent Rab27a effector coronin 3 in actin assembly and endocytosis of the insulin granule membranes2009
- Author(s)
  木村俊秀, 谷口繁生, 原口美帆, 東家一雄, 仁木一郎
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] マウス膵島における硫化水素の細胞保護作用2009
- Author(s)
  谷口繁生、金子雪子、木村俊秀、仁木一郎
- Organizer
  第82回日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-19591060
[Presentation] -急性期の腎・肺相関- 急性腎障害(AKI)は Acute Lung Injury/Acute Respiratory Distress Syndrome(ALI/ARDS)の予後規定因子である2009
- Author(s)
  林宏樹, 鈴木祥代, 倉田圭, 稲熊大城, 片岡健, 近藤康博, 谷口博之, 杉山大典, 西村邦宏, 佐藤和一, 丸山彰一, 湯澤由紀夫, 松尾清一
- Organizer
  第10回腎不全病態治療研究会
- Place of Presentation
  東京
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] -急性期の腎・肺相関- 急性腎障害(AKI)は Acute Lung Injury/Acute Respiratory Distress Syndrome(ALI/ARDS)の予後規定因子である2009
- Author(s)
  林宏樹, 鈴木祥代, 倉田圭, 稲熊大城, 片岡健, 近藤康博, 谷口博之, 杉山大典, 西村邦宏, 佐藤和一, 丸山彰一, 湯澤由紀夫, 松尾清一
- Organizer
  第1回 JAPAN AKI Summit
- Place of Presentation
  東京
- Year and Date
  2009-11-08
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] Roles of the GDP-dependent Rab27a effector coronin 3 in membrane traffic in the pancreatic beta cell2009
- Author(s)
  木村俊秀, 谷口繁生, 東家一雄, 仁木一郎
- Organizer
  45th Annual meeting of European Association for the Study of Diabetes
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] インクレチンの何が期待されているのか2009
- Author(s)
  仁木一郎, 木村俊秀, 谷口繁生
- Organizer
  第30回臨床薬理学会シンポジウム「糖尿病薬新薬開発と Clinical/Research Question の解決」
- Place of Presentation
  横浜
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21591146
[Presentation] GDP型Rab27a結合タンパク質coronin3によるアクチン細胞骨格制御とインスリン顆粒膜のリサイクリング2009
- Author(s)
  木村俊秀、谷口繁生、東家一雄、仁木一郎
- Organizer
  第82回日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-19591060
[Presentation] マウス眸島における硫化水素の細胞保護作用.2009
- Author(s)
  谷口繁生
- Organizer
  第82回日本薬理学会(横浜)
- Place of Presentation
  横浜
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-19591060
[Presentation] 膵B細胞におけるL-システィン代謝酵素の発現誘導を介した硫化水素産生調節.2008
- Author(s)
  谷口繁生
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19591060
[Presentation] 膵ランゲルハンス氏島における硫化水素産生酵素CSEの発現2008
- Author(s)
  谷口繁生、金子雪子、木村俊秀、仁木一郎
- Organizer
  第60回日本薬理学会西南部会
- Place of Presentation
  米子
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-19591060
[Presentation] 膵ランゲルハンス氏島における硫化水素産生酵素CSEの発現.2008
- Author(s)
  谷口繁生
- Organizer
  第60回日本薬理学会西南部会
- Place of Presentation
  米子
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-19591060
[Presentation] 膵B細胞におけるL-システイン代謝酵素の発現誘導を介した硫化水素産生調節2008
- Author(s)
  谷口繁生、金子雪子、木村俊秀、仁木一郎
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19591060
[Presentation] GDP型Rab27aはcoronin3と結合しインスリン顆粒膜のエンドサイトーシスを制御する2008
- Author(s)
  木村俊秀、山田将護、谷口繁生、仁木一郎
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19591060

1. KIMURA Toshihide (60404373)

# of Collaborated Projects: 3 results

# of Collaborated Products: 29 results
2. NIKI Ichiro (10262908)

# of Collaborated Projects: 2 results

# of Collaborated Products: 30 results
3. KANEKO Yukiko (00381038)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 湯澤由紀夫 (00191479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 黒川剛 (50291406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TANIGUCHI Shigeki 谷口 繁生

Research Projects

Research Products

Co-Researchers

Hydrogen sulfide protects insulin-secreting cells from cell damage-Characterization of the cytoprotective effects and the molecular mechanisms-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

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第3のガスメッセンジャー硫化水素の誘導性産生機序とその役割の解明

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Protection of pancreatic B-cell by the sulphur-containing amino acid L-cysteine and investigation of its underlying mechanisms

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[Journal Article] Protein phosphorylation involved in the gene expression of the hydrogen sulphide producing enzyme cystathionineγ-lyase in the pancreaticβ-cell2012

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[Journal Article] Protein phosphorylation involved in the gene expression of the hydrogen sulphide producing enzyme cystathionine γ-lyase in the pancreatic β-cell2012

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[Journal Article] Significance of hydrogen sulfide production in the pancreatic β-cell2011

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[Journal Article] Significance of hydrogen sulfide production in the pancreatic beta cell2011

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[Journal Article] Significance of hydrogen sulfide production in the pancreaticβ-cell2011

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[Journal Article] Hydrogen sulphide protects mouse pancreatic β-cells from cell death induced by oxidative stress, but not by endoplasmic reticulum stress2011

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[Journal Article] Hydrogen sulphide protects mouse pancreaticβ-cells from cell death induced by oxidative stress, but not by endoplasmic reticulum stress2011

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[Journal Article] Hydrogen sulphide protects mouse pancreatic β-cells from cell death induced by oxidative stress, but not by endoplasmic reticulum stress2011

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[Journal Article] Significance of Hydrogen Sulfide Production in the Pancreatic .BETA.-Cell2011

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[Journal Article] Actin assembly controlled by GDP-Rab27a is essential for endocytosis of the insulin secretory membrane.2010

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[Journal Article] Glucose-induced translocation of coronin 3 regulates the retrograde transport of the secretory membrane in the pancreatic β-cells2010

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[Journal Article] Actin assembly controlled by GDP-Rab27a is essential for endocytosis of the insulin secretory membrane2010

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[Journal Article] Glucose-induced production of hydrogen sulfide may protect the pancreatic beta-cells from apoptotic cell death by high glucose2009

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TANIGUCHI Shigeki 谷口繁生