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Shibayama Yuki  柴山 弓季

Researcher Number 90401190
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-9318-7801
Affiliation (based on the past Project Information) *help 2019 – 2021: 香川大学, 医学部, 研究員
2016 – 2017: 香川大学, 医学部, 博士研究員
Review Section/Research Field
Principal Investigator
Basic Section 50010:Tumor biology-related / Tumor biology
Keywords
Principal Investigator
ゲノム / ゲノム不安定性 / (プロ)レニン受容体 / 進化 / ドライバー遺伝子 / 膵管癌 / 癌 / (P)RR / クロマチンリモデリング / 発がん / 膵臓がん
  • Research Projects

    (2 results)
  • Research Products

    (29 results)
  • Co-Researchers

    (17 People)
  •  Evolutionary machanism of pancreatic ductal adenocarcinoma mediated by (pro)renin receptorPrincipal Investigator

    • Principal Investigator
      Shibayama Yuki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Kagawa University
  •  Functional analysis of (pro)renin receptor in the genesis of pancreatic cancerPrincipal Investigator

    • Principal Investigator
      Shibayama Yuki
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor biology
    • Research Institution
      Kagawa University

All 2021 2020 2019 2017 2016

All Journal Article Presentation

  • [Journal Article] Antiproliferative effects of monoclonal antibodies against (pro)renin receptor in pancreatic ductal adenocarcinoma2020

    • Author(s)
      Asadur Rahman , Makoto Matsuyama , Akio Ebihara , Yuki Shibayama , Arif Ul Hasan , Hironori Nakagami , Fumiaki Suzuki , Jiao Sun , Tomoe Kobayashi , Hiroki Hayashi , Daisuke Nakano , Hideki Kobara , Tsutomu Masaki , Akira Nishiyama
    • Journal Title

      Molecular Cancer Therapeutics

      Volume: 19 Issue: 9 Pages: 1844-1845

    • DOI

      10.1158/1535-7163.mct-19-0228

    • NAID

      130007811853

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07690, KAKENHI-PROJECT-18H03191
  • [Journal Article] Aberrant (pro)renin receptor expression induces genomic instability in pancreatic ductal adenocarcinoma through upregulation of SMARCA5/SNF2H2020

    • Author(s)
      Shibayama,Y., Takahashi, K., Yamaguchi, H., Yasuda, J., Yamazaki, D., Rahman, A., Fujimori, T., Fujisawa, Y., Takai, S., Furukawa, T., Nakagawa, T., Ohsaki, H., Kobara, H., Wong, J.H., Masaki, T., Yuzawa, Y., Kiyomoto, H., Yachida, S., Fujimoto, A., Nishiyama, A.
    • Journal Title

      Communications Biology

      Volume: 3 Issue: 1 Pages: 724-724

    • DOI

      10.1038/s42003-020-01434-x

    • NAID

      130008001357

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07690, KAKENHI-PLANNED-18H05511, KAKENHI-PROJECT-18H03191, KAKENHI-PROJECT-19H03795, KAKENHI-PROJECT-17K07193
  • [Journal Article] (Pro)renin receptor promotes colorectal cancer through the Wnt/beta-catenin signaling pathway despite constitutive pathway component mutations2019

    • Author(s)
      Wang, J, Shibayama, Y, Zhang, A, Ohsaki, H, Asano, E, Suzuki, Y, Kushida, Y, Kobara, H, Kato, K, Wang, Z, Nishiyama, A
    • Journal Title

      Br. J. Cancer

      Volume: 120 Issue: 2 Pages: 229-237

    • DOI

      10.1038/s41416-018-0350-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07690
  • [Journal Article] IBMX protects human proximal tubular epithelial cells from hypoxic stress through suppressing hypoxia-inducible factor-1α expression2017

    • Author(s)
      Hasan Arif Ul、Kittikulsuth Wararat、Yamaguchi Fuminori、Musarrat Ansary Tuba、Rahman Asadur、Shibayama Yuki、Nakano Daisuke、Hitomi Hirofumi、Tokuda Masaaki、Nishiyama Akira
    • Journal Title

      Experimental Cell Research

      Volume: 358 Issue: 2 Pages: 343-351

    • DOI

      10.1016/j.yexcr.2017.07.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09266, KAKENHI-PROJECT-16K14610
  • [Journal Article] Letter to the Editor. Expression of tissue (pro)renin receptor and concentrations of its soluble form in CSF in adult diffuse gliomas response2017

    • Author(s)
      Kouchi M, Shibayama Y, Ogawa D, Miyake K, Nishiyama A, Tamiya T
    • Journal Title

      J Neurosurg

      Volume: 127 Issue: 4 Pages: 962-964

    • DOI

      10.3171/2017.2.jns17254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K14610
  • [Journal Article] High glucose augments angiotensinogen in human renal proximal tubular cells through hepatocyte nuclear factor-5.2017

    • Author(s)
      Wang J, Shibayama Y, Kobori H, Liu Y, Kobara H, Masaki T, Wang Z, Nishiyama A.
    • Journal Title

      PLoS One

      Volume: 12 Issue: 10 Pages: e0185600-e0185600

    • DOI

      10.1371/journal.pone.0185600

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K14610
  • [Journal Article] (Pro)renin receptor is crucial for glioma development via the Wnt/β-catenin signaling pathway.2016

    • Author(s)
      Kochi m. Shibayama Y, Ogawa D, Miyake K, Nishiyama A, Tamiya T
    • Journal Title

      J Neurosurg

      Volume: epub Issue: 4 Pages: 1-10

    • DOI

      10.3171/2016.9.jns16431

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26293324, KAKENHI-PROJECT-16K14610, KAKENHI-PROJECT-15K19973
  • [Presentation] Aberrant (pro)renin receptor expression induces genomic instability in pancreatic ductal adenocarcinoma through upregulation of SMARCA5/SNFH2021

    • Author(s)
      Akira Nishiyama , Yuki Shibayama
    • Organizer
      第94回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19K07690
  • [Presentation] 膠芽腫に対する(Pro)renin receptorを標的とした分子治療の基礎的研究2021

    • Author(s)
      鈴木健太 , 藤森健司 , 小川大輔 , 菅田峻光 , 柴山弓季 , 西山 成 , 三宅啓介
    • Organizer
      第21回日本分子脳神経外科学会
    • Data Source
      KAKENHI-PROJECT-19K07690
  • [Presentation] ATP6ap2/(P)RR過剰発現ヒト膵管上皮細胞を用いた膵管癌の進化モデルの検討2021

    • Author(s)
      柴山弓季 , 西山 成
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K07690
  • [Presentation] Aberrant (pro)renin receptor expression induces genomic instability by SMARCA5 disruption during the development of pancreatic ductal adenocarcinoma2020

    • Author(s)
      Nishiyama, A , Shibayama, Y
    • Organizer
      Hypertension 2020 Scientific Sessions
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07690
  • [Presentation] ヒト膵管上皮細胞における(プロ)レニン受容体発現の亢進は、クロマチンリモデラー発現の増大を介してゲノム不安定性を生じる2019

    • Author(s)
      柴山弓季, 西山 成
    • Organizer
      第92回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K07690
  • [Presentation] Antiproliferative effects of monoclonal antibodies against (pro)renin receptor in pancreatic ductal adenocarcinoma2019

    • Author(s)
      Akira Nishiyama, Makoto Matsuyama, Yuki Shibayama, Akio Ebihara, Asadur Rahman
    • Organizer
      Hypertension 2019 Scientific Sessions
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07690
  • [Presentation] Effects of monoclonal antibodies against (pro)renin receptor in pancreatic ductal adenocarcinoma2019

    • Author(s)
      Rahman Asadur, 松山 誠, 海老原章郎, 柴山弓季, 鈴木文昭, 西山 成
    • Organizer
      第29回日本循環薬理学会
    • Data Source
      KAKENHI-PROJECT-19K07690
  • [Presentation] プロレニン受容体をターゲットとした膵癌治療法の開発2019

    • Author(s)
      西山 成, 柴山弓季
    • Organizer
      第92回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K07690
  • [Presentation] 膠芽腫およびグリオーマ幹細胞に対する (Pro)renin receptorを標的とした分子治療の基礎的研究2019

    • Author(s)
      藤森健司, 小川大輔, 河内雅章, 柴山弓季, 岡田真樹, 三宅啓介, 西山 成, 田宮 隆
    • Organizer
      第20回日本分子脳神経外科学会
    • Data Source
      KAKENHI-PROJECT-19K07690
  • [Presentation] (プロ)レニン受容体の発現亢進によって生じるゲノム不安定性2019

    • Author(s)
      柴山弓季, 西山 成
    • Organizer
      第92回日本内分泌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07690
  • [Presentation] 高血糖はヒト近位尿細管細胞のアンジオテンシノーゲンの発現をhepatocyte nuclear factor-5を介して亢進する2017

    • Author(s)
      西山 成、柴山弓季、小堀浩幸、Wang, J.
    • Organizer
      第90回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-16K14610
  • [Presentation] (プロ)レニン受容体発現の亢進は、ヒト膵管上皮細胞のゲノム不安定性を生じる2017

    • Author(s)
      柴山弓季、安田純、谷内田真一、西山 成
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K14610
  • [Presentation] (Pro)renin receptor promotes colorectal cancer through Wnt/be-ta catenin pathway despite of constructive mutations2017

    • Author(s)
      Wang, J., Shibayama, Y., Nishiyama, A.
    • Organizer
      第40回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-16K14610
  • [Presentation] Aberration of (pro)renin receptor induces genomic instability in human pancreatic ductal epithelial cells2017

    • Author(s)
      Shibayama, Y., Yasuda, J., Yamazaki, D., Rahman, A., Yachida, S., Nishiyama, A.
    • Organizer
      AACR Annual Meeting 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K14610
  • [Presentation] (プロ)レニン受容体発現の増大によって生じるゲノム不安定性の分子メカニズム2017

    • Author(s)
      柴山弓季、西山 成
    • Organizer
      ConsBio2017
    • Data Source
      KAKENHI-PROJECT-16K14610
  • [Presentation] 膵臓癌治療の新たなアプローチ2017

    • Author(s)
      西山 成、谷内田真一、柴山弓季
    • Organizer
      第76回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K14610
  • [Presentation] 大腸がんの病態における(プロ)レニン受容体の関与2016

    • Author(s)
      西山 成、柴山弓季、Wang Juan
    • Organizer
      第53回日本臨床分子医学会学術集会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2016-04-15
    • Data Source
      KAKENHI-PROJECT-16K14610
  • [Presentation] (プロ)レニン受容体過剰発現で生じるヒト膵管上皮細胞のゲノム不安定性2016

    • Author(s)
      柴山弓季、安田 純、西山 成
    • Organizer
      第39回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16K14610
  • [Presentation] Role of (Pro)renin receptor in the activation of Wnt/β-catenin pathway in colon cancer2016

    • Author(s)
      Wang, J., Shibayama,Y., Nakano, D. Hitomi, H. and Nishiyama, A.
    • Organizer
      HYPERTENSION SEOUL. 26th Scientific Meeting of the ISH.
    • Place of Presentation
      Corex, Seoul, Korea
    • Year and Date
      2016-09-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K14610
  • [Presentation] 神経膠腫におけるWnt/β-catenin を介した(pro)renin receptorの発現と役割2016

    • Author(s)
      河内雅章、柴山弓季、小川大輔、三宅啓介、西山 成、田宮 隆
    • Organizer
      第17回日本分子脳神経外科学会
    • Place of Presentation
      帝京大学板橋キャンパス
    • Year and Date
      2016-08-26
    • Data Source
      KAKENHI-PROJECT-16K14610
  • [Presentation] (Pro)renin receptor is pivotal for Wnt/β-catenin-dependent genesis of pancreatic ductal adenocarcinoma2016

    • Author(s)
      Shibayama, Y., Yachida, S., Rahman, A. and Nishiyama, A.
    • Organizer
      第47回日本膵臓学会・第20回国際膵臓学会・第6回アジアオセアニア膵臓学会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2016-08-04
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K14610
  • [Presentation] 膵臓がんにおける(プロ)レニン受容体とWnt/β-catenin経路を介した腫瘍進展2016

    • Author(s)
      柴山弓季、谷内田真一、西山 成
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-16K14610
  • 1.  NISHIYAMA Akira
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 2.  YASUDA Jun
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 3.  YACHIDA Shinichi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 4.  KIYOMOTO Hideyasu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  MASAKI Tsutomu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  YUZAWA Yukio
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TAKAI Shinji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  TAKAHASHI Kazuo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  YAMAGUCHI Hisateru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  FUJISAWA Yoshihide
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  YAMAZAKI Daisuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  FUJIMORI Takayuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  RAHMAN Asadur
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 14.  HITOMI Hirofumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  田宮 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  三宅 啓介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  小川 大輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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