Imai Chihaya 今井千速

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IMAI Chihaya 今井千速

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Researcher Number	90419284
Other IDs	https://orcid.org/0000-0001-7435-3464
Affiliation (Current)	2025: 富山大学, 学術研究部医学系, 教授
Affiliation (based on the past Project Information) *help	2023 – 2025: 富山大学, 学術研究部医学系, 教授 2014 – 2023: 新潟大学, 医歯学系, 准教授 2012 – 2013: 新潟大学, 医歯学総合病院, 講師 2007 – 2011: Niigata University, 医歯学系, 助教 2006: 新潟大学, 医歯学系, 助手
Review Section/Research Field	Principal Investigator Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Pediatrics
Keywords	Principal Investigator NK細胞 / NKp44 / NK細胞受容体 / CAR-T細胞 / キメラ抗原受容体 / 白血病 / chimeric receptor / 細胞療法 / 難治がん / CAR … More / がん免疫療法 / NKG2D / CD19 / 造血幹細胞移植 / リンパ腫 / 小児がん / 脳腫瘍 / 肉腫 / メモリー様NK細胞 / CAR-NK細胞 / HER2 / NKp30 / childhood cancer / cytotoxic T cell / 遺伝子改変リンパ球 / Natural killer cell / solid tumor / sarcoma / cancer immunotherapy / KIR haplotype / NK cell / Trogocytosis / trogocytosis / KIR / がん / CD4^+T細胞 / CD4^+ T細胞 / B細胞性腫瘍 / キメラ型受容体 / CD28 / 4-1BB / 臍帯血移植 / 難治性白血病 / Chimeric receptor / IL-2 / 遺伝子導入 … More Except Principal Investigator 細胞療法 / 腫瘍免疫 / 免疫細胞療法 / CAR-NK / CAR / NK細胞増幅 / 膜結合型キメラサイトカイン / NK細胞療法 / NK細胞 / 膜結合型サイトカイン / ウイルス / パレコウイルス / 敗血症 / モノクローナル抗体 / 移行抗体 / ヒトパレコウイルス3型 / 小児 / 治療 / 乳児 / 新生児 / パレコウイルスA3 / 免疫チェックポイント分子 / T細胞療法 / Programmed cell death-1 / キメラ抗原受容体 Less

白血病、脳腫瘍、肉腫、芽腫に幅広く使える大量生産型CAR-NK細胞療法の開発Principal Investigator
- Principal Investigator
  
  今井千速
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  University of Toyama
メモリー様分化誘導を基盤とした多種類のがんに有効なCAR-NK細胞製剤の新規開発Principal Investigator
- Principal Investigator
  
  今井千速
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  University of Toyama
  Niigata University
Novel CAR-NK cell therapies that are safe, effective and can be used by anyone at any time
- Principal Investigator
  
  Masaru Imamura
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Niigata University
Development of Novel CAR-T cell with NK cell-like specificity against refractory cancerPrincipal Investigator
- Principal Investigator
  
  Imai Chihaya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Niigata University
Development of NK Cell expansion by a novel membrane-bound chimeric cytokine
- Principal Investigator
  
  Imamura Masaru
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Niigata University
Investigations for Effective Therapies for Human Parechovirus Type 3 Infection
- Principal Investigator
  
  Saitoh Akihiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University
Development of Novel Immunotherapy of Cancer: NKp44-based Chimeric Antigen Receptors and Methods for Ex Vivo NK cell ExpansionPrincipal Investigator
- Principal Investigator
  
  Imai Chihaya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University
Development of a novel chimeric antigen receptor T cell immunotherapy targeting immune checkpoint molecules
- Principal Investigator
  
  IMAMURA Masaru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University
Studies towards development of more effective NK cell therapy: Finding genetic determinants for selection of best NK cell donors and a novel method for transfer of chimeric antigen receptor proteinPrincipal Investigator
- Principal Investigator
  
  Imai Chihaya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University
Translational Research on the Use of Genetically Modified HumanNatural Killer Cells for Refractory Leukemia.Principal Investigator
- Principal Investigator
  
  IMAI Chihaya
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University
Development of a novel therapy against refractory leukemia and lymphoma by using genetically-modified natural killer cellsPrincipal Investigator
- Principal Investigator
  
  IMAI Chihaya
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University

[Book] 今日の治療指針2024版．「小児の特発性血小板減少性紫斑病」1487-1488ページ2024
- Author(s)
  今井千速　分担執筆（総編集：福井次矢、高木誠、小室一成）
- Total Pages
  2224
- Publisher
  医学書院
- ISBN
  9784260053426
- Data Source
  KAKENHI-PROJECT-23K24297
[Book] 小児血液・腫瘍学改訂第2版　「CAR-T療法」2022
- Author(s)
  今井千速　分担執筆（日本小児血液・がん学会編）
- Total Pages
  640
- Publisher
  診断と治療社
- ISBN
  9784787824899
- Data Source
  KAKENHI-PROJECT-23K24297
[Book] 今日の処方　改訂第6版2019
- Author(s)
  今井千速
- Publisher
  南江堂
- ISBN
  9784524251193
- Data Source
  KAKENHI-PROJECT-19K08317
[Book] 小児の鉄欠乏性貧血.今目の治療指針2011(山口徹, 北原光夫, 福井次矢総編集)2011
- Author(s)
  今井千速(分担執筆)
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21591349
[Book] 遺伝性球状赤血球症.G6PD欠乏症(グルコース6リン酸脱水素酵素欠乏症).家庭医学大全科2010
- Author(s)
  今井千速(分担執筆)
- Publisher
  法研
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] Multi-omics analyses of choroid plexus carcinoma cell lines reveal potential targetable pathways and alterations2024
- Author(s)
  Hesham Dina、On Jotaro、Alshahaby Nouran、Amer Nada、Magdeldin Sameh、Okada Masayasu、Tsukamoto Yoshihiro、Hiraishi Tetsuya、Imai Chihaya、Okuda Shujiro、Wakai Toshifumi、Kakita Akiyoshi、Oishi Makoto、El-Naggar Shahenda、Natsumeda Manabu
- Journal Title
  
  Journal of Neuro-Oncology
  
  Volume: 166 Issue: 1 Pages: 27-38
- DOI
  10.1007/s11060-023-04484-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0156, KAKENHI-PROJECT-22K09251, KAKENHI-PROJECT-23K24297
[Journal Article] Isolated salivary gland extramedullary relapse of Philadelphia chromosome-positive acute lymphoblastic leukemia during blinatumomab treatment2024
- Author(s)
  Kawakami Yugo、Imamura Masaru、Imai Chihaya
- Journal Title
  
  International Journal of Hematology
  
  Volume: 119 Issue: 5 Pages: 479-480
- DOI
  10.1007/s12185-024-03756-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24297
[Journal Article] Successful Multimodal Treatment of Intracranial Growing Teratoma Syndrome with Malignant Features.2024
- Author(s)
  Satake D, Natsumeda M, Satomi K, Tada M, Sato T, Okubo N, Kawabe K, Takahashi H, Tsukamoto Y, Okada M, Sano M, Iwabuchi H, Shibata N, Imamura M, Imai C, Takami H, Ichimura K, Nishikawa R, Umezu H, Kakita A, Oishi M.
- Journal Title
  
  Current Oncology
  
  Volume: 31 Issue: 4 Pages: 1831-1838
- DOI
  10.3390/curroncol31040138
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06951, KAKENHI-PROJECT-23K24297
[Journal Article] Regression of kaposiform lymphangiomatosis and chronic disseminated intravascular coagulation after inhaled budesonide‐formoterol treatment2024
- Author(s)
  Imamura Masaru、Shin Chansu、Ozeki Michio、Matsuoka Kentaro、Saitoh Akihiko、Imai Chihaya
- Journal Title
  
  Pediatric Blood and Cancer
  
  Volume: 71 Issue: 4
- DOI
  10.1002/pbc.30907
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24297
[Journal Article] Rinketsu Dictionary, 4-1BB.2023
- Author(s)
  今井千速．
- Journal Title
  
  臨床血液
  
  Volume: 64 Pages: 315-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24297
[Journal Article] Nelarabine, intensive L-asparaginase, and protracted intrathecal therapy for newly diagnosed T-cell acute lymphoblastic leukaemia in children and young adults (ALL-T11): a nationwide, multicenter, phase 2 trial including randomisation in the very high-risk group2023
- Author(s)
  Sato Atsushi、Hatta Yoshihiro、Imai Chihaya、Oshima Koichi、Okamoto Yasuhiro、Deguchi Takao、Hashii Yoshiko、Fukushima Takashi、Hori Toshinori、Kiyokawa Nobutaka、Kato Motohiro、Saito Shoji、Anami Kenichi、Sakamoto Tatsuhiro、Kosaka Yoshiyuki、Suenobu Souichi、et al.
- Journal Title
  
  The Lancet Haematology
  
  Volume: 10 Issue: 6 Pages: e419-e432
- DOI
  10.1016/s2352-3026(23)00072-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07866, KAKENHI-PROJECT-22K08490, KAKENHI-PROJECT-18K07822, KAKENHI-PROJECT-21K07851, KAKENHI-PROJECT-23K24297, KAKENHI-PROJECT-23K27624
[Journal Article] NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcoma2023
- Author(s)
  Yudai Murayama, Yasushi Kasahara, Nobuhiro Kubo, Chansu Shin, Masaru Imamura, Naoki Oike, Takashi Ariizumi, Akihiko Saitoh, Minori Baba, Tomohiro Miyazaki, Yuko Suzuki, Yiwei Ling, Shujiro Okuda, Keichiro Mihara, Akira Ogose, Hiroyuki Kawashima, Chihaya Imai
- Journal Title
  
  Transl Oncol
  
  Volume: ahead Pages: 1-1
- DOI
  10.1016/j.tranon.2022.101521
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17850, KAKENHI-PROJECT-23K24297
[Journal Article] 遺伝子細胞療法．2023
- Author(s)
  今井千速．
- Journal Title
  
  小児科診療．
  
  Volume: 86号（8巻） Pages: 863-867
- Data Source
  KAKENHI-PROJECT-23K24297
[Journal Article] Outcome for Children and Young Adults With T-Cell ALL and Induction Failure in Contemporary Trials2023
- Author(s)
  Raetz Elizabeth A.、Rebora Paola、Conter Valentino、Schrappe Martin、Devidas Meenakshi、Escherich Gabriele、Imai Chihaya、et al.
- Journal Title
  
  Journal of Clinical Oncology
  
  Volume: 41 Issue: 32 Pages: 5025-5034
- DOI
  10.1200/jco.23.00088
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24297
[Journal Article] Time Course of Conical Teeth in Anhidrotic Ectodermal Dysplasia with Immunodeficiency2022
- Author(s)
  Aizawa Yuta、Imai Chihaya、Saitoh Akihiko
- Journal Title
  
  Journal of Clinical Immunology
  
  Volume: 42 Issue: 6 Pages: 1168-1170
- DOI
  10.1007/s10875-022-01300-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24297
[Journal Article] Epigenetic upregulation of Schlafen11 renders WNT- and SHH-activated medulloblastomas sensitive to cisplatin2022
- Author(s)
  Nakata Satoshi、Murai Junko、Okada Masayasu,,,,,Tateishi Kensuke、Yamashita Shinji、Eberhart Charles G、Natsumeda Manabu
- Journal Title
  
  Neuro-Oncology
  
  Volume: 25 Issue: 5 Pages: 899-912
- DOI
  10.1093/neuonc/noac243
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09210, KAKENHI-PROJECT-22K16679, KAKENHI-PROJECT-21KK0156, KAKENHI-PROJECT-20K15919, KAKENHI-PROJECT-23K24297, KAKENHI-PROJECT-22K20953, KAKENHI-PROJECT-21H03042
[Journal Article] Discontinuation of tyrosine kinase inhibitors in pediatric chronic myeloid leukemia2022
- Author(s)
  Shima Haruko、Kada Akiko、Tanizawa Akihiko、Sato Iori、Tono Chikako、Ito Masaki、Yuza Yuki、Watanabe Akihiro、Kamibeppu Kiyoko、Uryu Hideko、Koh Katsuyoshi、Imai Chihaya、Yoshida Nao、Koga Yuhki、Fujita Naoto、Saito Akiko M.、Adachi Souichi、Ishii Eiichi、Shimada Hiroyuki
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: 69 Issue: 8
- DOI
  10.1002/pbc.29699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24297
[Journal Article] Dual-antigen targeted iPSC-derived chimeric antigen receptor-T cell therapy for refractory lymphoma2022
- Author(s)
  Harada Sakiko、Ando Miki、Ando Jun、Ishii Midori、Yamaguchi Tomoyuki、Yamazaki Satoshi、Toyota Tokuko、Ohara Kazuo、Ohtaka Manami、Nakanishi Mahito、Shin Chansu、Ota Yasunori、Nakashima Kazutaka、Ohshima Koichi、Imai Chihaya、Nakazawa Yozo、Nakauchi Hiromitsu、Komatsu Norio
- Journal Title
  
  Molecular Therapy
  
  Volume: 30 Issue: 2 Pages: 534-549
- DOI
  10.1016/j.ymthe.2021.10.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07781, KAKENHI-PROJECT-19K08317, KAKENHI-PROJECT-20K21612, KAKENHI-PUBLICLY-20H05025, KAKENHI-PROJECT-20H03707, KAKENHI-PROJECT-20H03740, KAKENHI-PROJECT-21F21108, KAKENHI-PROJECT-21K07249
[Journal Article] Short stature as an initial presenting presentation of unicentric Castleman disease in a child: A case report with long-term follow-up and a literature review2022
- Author(s)
  Sonoda Kaori、Kaneko Utako、Hiura Makoto、Kinoshita Yoshiaki、Umezu Hajime、Ito Shuichi、Saitoh Akihiko、Imai Chihaya
- Journal Title
  
  Modern Rheumatology Case Reports
  
  Volume: 7 Issue: 1 Pages: 261-266
- DOI
  10.1093/mrcr/rxac034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24297, KAKENHI-PROJECT-21K08661
[Journal Article] Resolution of Pediococcus acidilactici bacteremia without antibiotic therapy in a 16-year-old adolescent with leukemia receiving maintenance chemotherapy2022
- Author(s)
  Tachikawa Jun、Aizawa Yuta、Izumita Ryohei、Shin Chansu、Imai Chihaya、Saitoh Akihiko
- Journal Title
  
  IDCases
  
  Volume: 27 Pages: e01384-e01384
- DOI
  10.1016/j.idcr.2022.e01384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08317
[Journal Article] Newly diagnosed ETV6-RUNX1?positive B-acute lymphoblastic leukemia localized to the left pelvic bone marrow2022
- Author(s)
  Baba Minori、Imamura Masaru、Imai Chihaya
- Journal Title
  
  International Journal of Hematology
  
  Volume: 115 Issue: 2 Pages: 151-152
- DOI
  10.1007/s12185-021-03269-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08317, KAKENHI-PROJECT-23K24297
[Journal Article] BRAFV600E-positive cells as molecular markers of bone marrow disease in pediatric Langerhans cell histiocytosis.2022
- Author(s)
  Ko Kudo, Tsutomu Toki, Rika Kanezaki, and Etsuro Ito
- Journal Title
  
  Haematologica
  
  Volume: epub ahead Issue: 7 Pages: 000-000
- DOI
  10.3324/haematol.2021.279857
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07813, KAKENHI-PROJECT-21K06909, KAKENHI-PROJECT-21K06938, KAKENHI-PROJECT-20K07442, KAKENHI-PROJECT-23K21429, KAKENHI-PROJECT-23K24297
[Journal Article] NK細胞の活性化受容体を利用したキメラ抗原受容体．2021
- Author(s)
  笠原靖史, 今井千速
- Journal Title
  
  日本小児血液・がん学会雑誌
  
  Volume: 58 Pages: 185-193
- NAID
  130008116127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08317
[Journal Article] 膠芽腫に対するCAR-T細胞療法．2021
- Author(s)
  笠原靖史, 今井千速
- Journal Title
  
  小児の脳神経（Nervous System in Children）
  
  Volume: 46 Pages: 211-219
- NAID
  130008095352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08317
[Journal Article] 小児悪性固形腫瘍に対するCAR-T細胞療法の開発2021
- Author(s)
  今井千速
- Journal Title
  
  BIO Clinica
  
  Volume: 35 Pages: 1155-1159
- Data Source
  KAKENHI-PROJECT-19K08317
[Journal Article] CAR-NK細胞の初期開発に携わっての所感2021
- Author(s)
  今井千速
- Journal Title
  
  日本血液疾患免疫療法学会Newsletter
  
  Volume: 12 Pages: 11-11
- Data Source
  KAKENHI-PROJECT-19K08317
[Journal Article] Effectiveness of 4-1BB-costimulated HER2-targeted chimeric antigen receptor T cell therapy for synovial sarcoma2021
- Author(s)
  Murayama Yudai、Kawashima Hiroyuki、Kubo Nobuhiro、Shin Chansu、Kasahara Yasushi、Imamura Masaru、Oike Naoki、Ariizumi Takashi、Saitoh Akihiko、Mihara Keichiro、Umezu Hajime、Ogose Akira、Imai Chihaya
- Journal Title
  
  Translational Oncology
  
  Volume: 14 Issue: 12 Pages: 101227-101227
- DOI
  10.1016/j.tranon.2021.101227
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08317
[Journal Article] Human leukocyte antigen I is significantly downregulated in patients with myxoid liposarcomas2021
- Author(s)
  Oike N, Kawashima H, Ogose A et al
- Journal Title
  
  Cancer Immunology Immunotherapy
  
  Volume: ahead on print Issue: 12 Pages: 3489-3499
- DOI
  10.1007/s00262-021-02928-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09098, KAKENHI-PROJECT-19K08317
[Journal Article] 骨・軟部腫瘍における免疫環境と免疫治療．2021
- Author(s)
  13.生越章，川島寛之，有泉高志，大池直樹，村山雄大，今井千速．
- Journal Title
  
  BIO Clinica
  
  Volume: 35 Pages: 1155-1159
- Data Source
  KAKENHI-PROJECT-19K08317
[Journal Article] 肢端紅痛症で発症し、無症候性後天性フォンウィルブランド症候群を合併した本態性血小板血症の小児例．2021
- Author(s)
  村山ゆり恵，田屋光将，申将守，馬場みのり，岩渕晴子，今村勝，齋藤昭彦，今井千速．
- Journal Title
  
  小児科臨床．
  
  Volume: 74 Pages: 553-558
- NAID
  40022543264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08317
[Journal Article] Case Report: Analysis of Preserved Umbilical Cord Clarified X-Linked Anhidrotic Ectodermal Dysplasia With Immunodeficiency in Deceased, Undiagnosed Uncles2021
- Author(s)
  Inaba Satoshi、Aizawa Yuta、Miwa Yuki、Imai Chihaya、Ohnishi Hidenori、Kanegane Hirokazu、Saitoh Akihiko
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 786164-786164
- DOI
  10.3389/fimmu.2021.786164
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08317, KAKENHI-PROJECT-21K07770
[Journal Article] Drug‐induced panniculitis in a child with acute lymphoblastic leukemia2021
- Author(s)
  Iwabuchi Haruko、Takachi Takayuki、Kubo Nobuhiro、Imamura Masaru、Umezu Hajime、Saitoh Akihiko、Imai Chihaya
- Journal Title
  
  Pediatric Blood and Cancer
  
  Volume: 69 Issue: 5
- DOI
  10.1002/pbc.29501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08317
[Journal Article] Nationwide study of pediatric B-cell precursor acute lymphoblastic leukemia with chromosome 8q24/MYC rearrangement in Japan.2020
- Author(s)
  Sakaguchi K, Imamura T, Ishimaru S, Imai C, Shimonodan H, Fujita N, Okada K, Taketani T, Kanai R, Tauchi H, Kato M, Kojima Y, Watanabe A, Deguchi T, Hashii Y, Kiyokawa N, Taki T, Saito AM, Horibe K, Manabe A, Sato A, Koh K.
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 67 Issue: 7
- DOI
  10.1002/pbc.28341
- NAID
  120007161473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08317, KAKENHI-PROJECT-18K08335
[Journal Article] Fatal Progressive Meningoencephalitis Diagnosed in Two Members of a Family With X-Linked Agammaglobulinemia2020
- Author(s)
  Yasushi Kasahara, Masaru Imamura, Chansu Shin, Hiroshi Shimizu, Jirou Utsumi, Ryosuke Hosokai, Haruko Iwabuchi, Takayuki Takachi, Akiyoshi Kakita, Hirokazu Kanegane, Akihiko Saitoh, Chihaya Imai
- Journal Title
  
  Frontiers in Pediatrics
  
  Volume: 8 Pages: 579-579
- DOI
  10.3389/fped.2020.00579
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07841, KAKENHI-PROJECT-19K08317
[Journal Article] History and perspectives of chimeric antigen receptor-T cell therapy2020
- Author(s)
  今井千速
- Journal Title
  
  The Japanese Journal of Pediatric Hematology / Oncology
  
  Volume: 57 Issue: 5 Pages: 354-359
- DOI
  10.11412/jspho.57.354
- NAID
  130007987007
- ISSN
  2187-011X, 2189-5384
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08317
[Journal Article] Development and characterisation of NKp44‐based chimeric antigen receptors that confer T cells with NK cell‐like specificity2020
- Author(s)
  Kasahara Yasushi、Shin Chansu、Kubo Nobuhiro、Mihara Keichiro、Iwabuchi Haruko、Takachi Takayuki、Imamura Masaru、Saitoh Akihiko、Imai Chihaya
- Journal Title
  
  Clinical & Translational Immunology
  
  Volume: 9 Issue: 7 Pages: 1-19
- DOI
  10.1002/cti2.1147
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08317
[Journal Article] Partial IFN-γR1 deficiency complicated by disseminated BCG infection mimicking Langerhans cell histiocytosis2020
- Author(s)
  原田瑞生、岡田賢、今井千速、久保暢大、高地貴行、岩渕晴子、今村勝、齋藤昭彦、梅津哉、山中崇之、今井耕輔
- Journal Title
  
  The Japanese Journal of Pediatric Hematology / Oncology
  
  Volume: 57 Issue: 3 Pages: 309-313
- DOI
  10.11412/jspho.57.309
- NAID
  130007935415
- ISSN
  2187-011X, 2189-5384
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08317
[Journal Article] Current status of cancer immunotherapy for relapsed/refractory acute lymphoblastic leukemia in children and adolescents in Japan2020
- Author(s)
  今井千速
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 61 Issue: 6 Pages: 673-681
- DOI
  10.11406/rinketsu.61.673
- NAID
  130007869117
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08317
[Journal Article] Spontaneous remission of infant acute myeloid leukemia with a novel four-way translocation.2020
- Author(s)
  Kubo N, Iwabuchi H, Imamura M, Saitoh A, Imai C.
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 67 Issue: 2
- DOI
  10.1002/pbc.28052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08317
[Journal Article] In-Hospital Management Might Reduce Induction Deaths in Pediatric Patients With Acute Lymphoblastic Leukemia: Results From a Japanese Cohort2020
- Author(s)
  Nakagawa Shunsuke、Kato Motohiro、Imamura Toshihiko、Imai Chihaya、Koh Katsuyoshi、Kawano Yoshifumi、Shimomura Yasuto、Watanabe Arata、Kikuta Atsushi、Saito Akiko、Horibe Keizo、Manabe Atsushi、Ohara Akira、Okamoto Yasuhiro
- Journal Title
  
  Journal of Pediatric Hematology/Oncology
  
  Volume: 43 Issue: 2 Pages: 39-46
- DOI
  10.1097/mph.0000000000001926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08317
[Journal Article] 繰り返す腸重積で発見されフローサイトメトリーでlight chain restrictionを認めた虫垂リンパ過形成の1例．2019
- Author(s)
  小貫孝則, 高地貴行, 久保暢大, 岩渕晴子, 今村勝, 齋藤昭彦, 今井千速
- Journal Title
  
  小児科臨床
  
  Volume: 72 Pages: 170-174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08317
[Journal Article] 骨病変を有したLangerhans細胞組織球症の3例2019
- Author(s)
  勝見達也, 新熊悟, 荻根沢真帆子, 河合亨, 加畑雄大, 折目真理, 伊藤明子, 久保暢大, 岩渕晴子, 今井千速, 阿部理一郎．
- Journal Title
  
  臨床皮膚科
  
  Volume: 73 Pages: 78-84
- Data Source
  KAKENHI-PROJECT-19K08317
[Journal Article] Nationwide survey of pediatric hypodiploid acute lymphoblastic leukemia in Japan2019
- Author(s)
  Ishimaru Sae、Okamoto Yasuhiro、Imai Chihaya、Sakaguchi Hirotoshi、Taki Tomohiko、Hasegawa Daisuke、Cho Yuko、Kakuda Harumi、Sano Hideki、Manabe Atsushi、Imamura Toshihiko、Kato Motohiro、Arakawa Yuki、Shimonodan Hidemi、Sato Atsushi、Suenobu Souichi、et al.
- Journal Title
  
  Pediatrics International
  
  Volume: 61 Issue: 11 Pages: 1103-1108
- DOI
  10.1111/ped.14006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07822, KAKENHI-PROJECT-18K08335, KAKENHI-PROJECT-19K08317, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-17K10117, KAKENHI-PROJECT-17K10129
[Journal Article] CAR-T細胞療法－遺伝子改変T細胞を用いた新しいがん治療2018
- Author(s)
  今井千速
- Journal Title
  
  小児科
  
  Volume: 59 Pages: 1583-1591
- Data Source
  KAKENHI-PROJECT-16K10015
[Journal Article] がん免疫療法：最近話題のPD-1抗体からCAR-T療法まで2018
- Author(s)
  今井千速
- Journal Title
  
  新潟県小児科医会会報
  
  Volume: 60 Pages: 17-20
- Data Source
  KAKENHI-PROJECT-16K10015
[Journal Article] 新潟県に子ども病院は必要か？　~小児科医の視点から．2017
- Author(s)
  今井千速．
- Journal Title
  
  新潟医学会雑誌．
  
  Volume: 131 Pages: 565-568
- Data Source
  KAKENHI-PROJECT-16K10015
[Journal Article] キメラ抗原受容体 (CAR): 人工受容体遺伝子を導入したリンパ球による新たながん治療．2017
- Author(s)
  今井千速
- Journal Title
  
  新潟医学会雑誌
  
  Volume: 131 Pages: 7-10
- NAID
  120006761894
- Data Source
  KAKENHI-PROJECT-16K10015
[Journal Article] 白血病に対する新しい薬物・細胞治療．2017
- Author(s)
  今井千速
- Journal Title
  
  日本医師会雑誌．
  
  Volume: 145 Pages: 2600-2604
- Data Source
  KAKENHI-PROJECT-16K10015
[Journal Article] Hematopoietic stem cell transplantation in 29 patients hemizygous for hypomorphicIKBKG/NEMO mutations2017
- Author(s)
  Miot C, Imai K, Imai C, Mancini AJ, Kucuk XY, Kawai T, Nishikomori R, Ito E, Pellier I, Girod SD, Rosain J, Sasaki S, Casanova JL, Orange JS, and Picard C et al.
- Journal Title
  
  Blood.
  
  Volume: 130 Issue: 12 Pages: 1456-1467
- DOI
  10.1182/blood-2017-03-771600
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-15H04876, KAKENHI-PROJECT-15K09640, KAKENHI-PROJECT-16K10015
[Journal Article] キメラ抗原受容体 (CAR): 人工受容体遺伝子を導入したリンパ球による新たながん治療．2017
- Author(s)
  今井千速．
- Journal Title
  
  新潟医学会雑誌．
  
  Volume: 131 Pages: 7-10
- NAID
  120006761894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10015
[Journal Article] Successful treatment of histiocytic sarcoma with cladribine and high-dose cytosine arabinoside in a child2017
- Author(s)
  Iwabuchi H, Kawashima H, Umezu H, Takachi T, Imamura M, Saitoh A, Ogose A, Imai C.
- Journal Title
  
  Int J Hematol.
  
  Volume: 106 Issue: 2 Pages: 299-303
- DOI
  10.1007/s12185-017-2202-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10015
[Journal Article] 白血病に対する新しい薬物・細胞治療2017
- Author(s)
  今井千速．
- Journal Title
  
  日本医師会雑誌．
  
  Volume: 145 Pages: 2600-2604
- Data Source
  KAKENHI-PROJECT-16K10015
[Journal Article] 軟部組織病変を呈し特異な臨床経過を示したランゲルハンス細胞組織球症の1例．2017
- Author(s)
  古寺一樹, 今村勝, 高地貴行, 申将守, 笠原靖史, 岩渕晴子, 川島寛之, 生越章, 梅津哉, 齋藤昭彦, 今井千速．
- Journal Title
  
  日本小児血液・がん学会雑誌．
  
  Volume: 54 Pages: 157-160
- NAID
  130005960310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10015
[Journal Article] Donor Killer Immunoglobulin-Like Receptor Haplotype B/x Induces Severe Acute Graft-versus-Host Disease in the Presence of Human Leukocyte Antigen Mismatch in T Cell-Replete Hematopoietic Cell Transplantation.2017
- Author(s)
  Hosokai R, Masuko M, Shibasaki Y, Saitoh A, Furukawa T, Imai C.
- Journal Title
  
  Biol Blood Marrow Transplant.
  
  Volume: 23(4) Issue: 4 Pages: 606-611
- DOI
  10.1016/j.bbmt.2016.12.638
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09868, KAKENHI-PROJECT-17K09006, KAKENHI-PROJECT-16K10015
[Journal Article] Hematopoietic stem cell transplantation for pediatric mature B-cell acute lymphoblastic leukemia with non-L3 morphology and MLL-AF9 gene fusion: three case reports and review of the literature.2016
- Author(s)
  Sarashina T, Iwabuchi H, Miyagawa N, Sekimizu M, Yokosuka T, Fukuda K, Hamanoue S, Iwasaki F, Goto S, Shiomi M, Imai C, Goto H.
- Journal Title
  
  Int J Hematol
  
  Volume: 104 Issue: 1 Pages: 139-143
- DOI
  10.1007/s12185-016-1971-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10015
[Journal Article] Anti-proliferative effects of T cells expressing a ligand-based chimeric antigen receptor against CD116 on CD34(+) cells of juvenile myelomonocytic leukemia2016
- Author(s)
  Nakazawa Y, Matsuda K, Kurata T, Sueki A, Tanaka M, Sakashita K, Imai C, Wilson MH, Koike K
- Journal Title
  
  J Hematol Oncol
  
  Volume: 9 Issue: 1 Pages: 27-27
- DOI
  10.1186/s13045-016-0256-3
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461574, KAKENHI-PROJECT-25461581, KAKENHI-PROJECT-15H04874, KAKENHI-PROJECT-15K19177, KAKENHI-PROJECT-16K10015
[Journal Article] Characterization of pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia with kinase fusions in Japan2016
- Author(s)
  Imamura T, Kiyokawa N, Kato M, Imai C, Okamoto Y, Yano M, Ohki K, Yamashita Y, Kodama Y, Saito A, Mori M, Ishimaru S, Deguchi T, Hashii Y, Shimomura Y, Hori T, Kato K, Goto H, Ogawa C, Koh K, Taki T, Manabe A, Sato A, Kikuta A, Adachi S, Horibe K, Ohara A, Watanabe A, Kawano Y, Ishii E, Shimada H
- Journal Title
  
  Blood Cancer J
  
  Volume: 6 Issue: 5 Pages: e419-e419
- DOI
  10.1038/bcj.2016.28
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09486, KAKENHI-PROJECT-16K10015
[Journal Article] All-trans retinoic acid enhances cytotoxic effect of T cells with an anti-CD38 chimeric antigen receptor in acute myeloid leukemia.2016
- Author(s)
  Yoshida T, Mihara K, Takei Y, Yanagihara K, Kubo T, Bhattacharyya J, Imai C, Mino T, Takihara Y, Ichinohe T.
- Journal Title
  
  Clin Trans Immunol
  
  Volume: 5 Issue: 12
- DOI
  10.1038/cti.2016.73
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H04697, KAKENHI-PROJECT-16K10015, KAKENHI-PROJECT-15K15063
[Journal Article] Secondary osteosarcoma arising from osteochondroma following autologous stem cell transplantation with total-body irradiation for neuroblastoma: A case report.2015
- Author(s)
  Kawashima H, Ogose A, Hotta T, Imai C, Imamura M, Endo N.
- Journal Title
  
  Oncol Lett
  
  Volume: 10(2) Pages: 1026-1030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461581
[Journal Article] T Lymphocytes Expressing a CD16 Signaling Receptor Exert Antibody-Dependent Cancer Cell Killing2014
- Author(s)
  Kudo K, Imai C, Lorenzini P, Kamiya T, Kono K, Davidoff AM, Chng WJ, Campana D
- Journal Title
  
  Cancer Res
  
  Volume: 74 Issue: 1 Pages: 93-103
- DOI
  10.1158/0008-5472.can-13-1365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461581
[Journal Article] 4-1BB Chimeric Antigen Receptors2014
- Author(s)
  Campana D, Schwarz H, Imai C
- Journal Title
  
  Cancer J
  
  Volume: 20 Issue: 2 Pages: 134-140
- DOI
  10.1097/ppo.0000000000000028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461581
[Journal Article] Autonomous growth and increased cytotoxicity of natural killer cells expressing membrane-bound interleukin-152014
- Author(s)
  Imamura M, Shook D, Kamiya T, Shimasaki N, Chai SM, Coustan-Smith E, Imai C, Campana D
- Journal Title
  
  Blood
  
  Volume: 124 Issue: 7 Pages: 1081-1088
- DOI
  10.1182/blood-2014-02-556837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461581
[Journal Article] 微小残存病変を用いた急性リンパ性白血病治療戦略2013
- Author(s)
  今井千速
- Journal Title
  
  小児内科
  
  Volume: 45 Pages: 1134-1136
- Data Source
  KAKENHI-PROJECT-25461581
[Journal Article] Alveolar rhabdomyosarcoma after treatment of osteosarcoma2013
- Author(s)
  Kasahara Y, Iwabuchi H, Takachi T, Hosokai R, Yoshida S, Imamura M, Watanabe A, Umezu H, Hotta T, Ogose A and Imai C
- Journal Title
  
  Pediatrics International
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] Alveolar rhabdomyosarcoma after treatment of osteosarcoma.2013
- Author(s)
  Kasahara Y, Iwabuchi H, Takachi T, Hosokai R, Yoshida S, Imamura M, Watanabe A, Umezu H, Hotta T, Ogose A, Imai C
- Journal Title
  
  Pediatr Int.
  
  Volume: 55 Issue: 4 Pages: 527-530
- DOI
  10.1111/ped.12070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461581
[Journal Article] Autoimmunity and persistent RAS- mutated clones long after the spontaneous regression of JMML2013
- Author(s)
  Takagi M, Imai C, et al
- Journal Title
  
  Leukemia
  
  Volume: 27 Issue: 9 Pages: 1926-1928
- DOI
  10.1038/leu.2013.82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349, KAKENHI-PROJECT-23591552, KAKENHI-PROJECT-24590368, KAKENHI-PROJECT-25461581
[Journal Article] ヒトNK細胞の体外増幅と遺伝子改変　～難治性白血病・がんの征圧に向けて2013
- Author(s)
  今井千速
- Journal Title
  
  日本小児血液・がん学会雑誌
  
  Volume: 50 Pages: 341-349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461581
[Journal Article] Frequent somatic mosaicism of NEMO in T cells of patients with X-linked anhidrotic ectodermal dysplasia with immune- deficiency2012
- Author(s)
  Kawai T, Imai C et al
- Journal Title
  
  Blood
  
  Volume: 119 Issue: 23 Pages: 5458-66
- DOI
  10.1182/blood-2011-05-354167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349, KAKENHI-PROJECT-22249042, KAKENHI-PROJECT-22591149, KAKENHI-PROJECT-22591161, KAKENHI-PROJECT-23390266, KAKENHI-PROJECT-23657147, KAKENHI-PROJECT-24659496
[Journal Article] 家系に複数の脾臓摘出者を認め遺伝性球状赤血球症と考えられていたHb Koeln症の一例2012
- Author(s)
  笠原靖史、細貝亮介、高地貴行、吉田咲子、今村勝、今井千速．
- Journal Title
  
  日本小児血液・がん学会雑誌
  
  Volume: 49 Pages: 138-141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] Lymphoblastic lymphoma with mature B-cell immunophenotype and MLL-AF9 in a child2011
- Author(s)
  Takachi T, Iwabuchi H, Imamura M, Imai C
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 57 Issue: 7 Pages: 1251-1252
- DOI
  10.1002/pbc.23228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] 急性リンパ性白血病治療中に発症し、アムホテリシンBリポソーム製剤が奏効した接合菌症の疑われる脳膿瘍の1例2011
- Author(s)
  細貝亮介、今井千速, ほか
- Journal Title
  
  日本小児血液学会雑誌
  
  Volume: 25 Pages: 97-101
- NAID
  10029312185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] Disseminated BCG Infection Mimicking Metastatic Nasopharyngeal Carcinoma in anImmunodeficient Child with a Novel Hypomorphic NEMO Mutation2011
- Author(s)
  Imamura M, Takachi T, Yoshida S, Imai C
- Journal Title
  
  J Clin Immunol
  
  Volume: 31 Issue: 5 Pages: 802-10
- DOI
  10.1007/s10875-011-9568-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] Autonomously functioning thyroid nodule in a four-year-old boy with Sotos syndrome2011
- Author(s)
  Nyuzuki H, Nagasaki K, Matsuyama H, Tomita M, Imai C, et al
- Journal Title
  
  Pediatr Int
  
  Volume: 53(1) Pages: 137-138
- NAID
  10029557486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] 小児・思春期白血病に対する本邦共通プロトコールの策定2011
- Author(s)
  今井千速
- Journal Title
  
  新潟医学会雑誌
  
  Volume: 125 Pages: 69-74
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] Synergistic and persistent effect of T-cell immunotherapy with anti-CD19 or anti-CD38 chimeric receptor in conjunction with rituximab on B-cell non-Hodgkin lymphoma2010
- Author(s)
  Mihara K, Imai C, et al
- Journal Title
  
  Br J Haematol
  
  Volume: 151 Issue: 1 Pages: 37-46
- DOI
  10.1111/j.1365-2141.2010.08297.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] Synergistic and persistent effect of T-cell immunotherapy with anti-CD19 or anti-CD38 chimeric receptor in conjunction with rituximab on B-cell non-Hodgkin lymphoma2010
- Author(s)
  Mihara K, Yanagihara K, Takigahira M, Kitanaka A, Imai C, et al
- Journal Title
  
  Br J Haematol
  
  Volume: 151(1) Pages: 37-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] NK細胞療法の基礎と展望(総説)2010
- Author(s)
  今井千速
- Journal Title
  
  小児がん
  
  Volume: 47 Pages: 268-274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] Reactive tonsillar enlargement with strong 18F-FDG uptake after chemotherapy for tonsillar diffuse large B cell lymphoma2010
- Author(s)
  Hosokai R, Imai C, et al
- Journal Title
  
  J Pediatr Hematol Oncol
  
  Volume: 33 Issue: 2 Pages: e87-e88
- DOI
  10.1097/mph.0b013e3181f69205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] Replicative potential of human natural killer cells2009
- Author(s)
  Fujisaki H, Kakuda H, Imai C, et al
- Journal Title
  
  Br J Haematol
  
  Volume: 145 Issue: 5 Pages: 606-13
- DOI
  10.1111/j.1365-2141.2009.07667.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] A novel homozygous8-base pair deletion mutation in the glycoprotein Ibalpha gene in a patient with Bernard-Soulier syndrome2009
- Author(s)
  Imai C, et al
- Journal Title
  
  Blood Coagul Fibrinolysis
  
  Volume: 20 Issue: 6 Pages: 470-4
- DOI
  10.1097/mbc.0b013e32832b27fa
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] Effect of charcoal hemoperfusion for removal of plasma methotrexate in a patient with acute renal failure2009
- Author(s)
  Nemoto T, Imai C, et al
- Journal Title
  
  Pediatr Hematol Oncol
  
  Volume: 26 Pages: 520-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] A novel homozygous 8-base pair deletion mutation in the glycoprotein Ibα gene in a patient with Bernard-Soulier syndrome2009
- Author(s)
  Imai C, et al.
- Journal Title
  
  Blood Coagulation & Fibrinolysis 20(6)
  
  Pages: 470-474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] Expansion of Highly Cytotoxic Human Natural Killer Cells for Cancer Cell Therapy2009
- Author(s)
  Fujisaki H, Kakuda H, Shimasaki N, Imai C, Ma J, Lockey T, Eldridge P, Leung WH, Campana D
- Journal Title
  
  Cancer Res
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790706
[Journal Article] A 2-year-old boy with a stage III yold sac tumor occurring in an intra-abdominal retained testis.2009
- Author(s)
  Hirayama Y, Imai C, et al.
- Journal Title
  
  Journal of Pediatric Surgery 44(12)
  
  Pages: 2395-2398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] Expansion of Highly Cytotoxic Human Natural Killer Cells for Cancer Cell Therapy2009
- Author(s)
  Fujisaki H, Imai C, et al
- Journal Title
  
  Cancer Res
  
  Volume: 69 Issue: 9 Pages: 4010-7
- DOI
  10.1158/0008-5472.can-08-3712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] NK細胞療法の基礎と展望～NK細胞の体外増幅と遺伝子改変を中心に2009
- Author(s)
  今井千速
- Journal Title
  
  第51回日本小児血液学会・第25回日本小児がん学会教育セッションテキスト
  
  Pages: 110-114
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] Activated T-cell-mediated immunotherapy with a chimeric receptor against CD38 in B-cell non-Hodgkin lymphoma.2009
- Author(s)
  Mihara K, Imai C, et al.
- Journal Title
  
  Journal of Immunotherapy 32
  
  Pages: 737-743
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] Effect of charcoal hemoperfusion for removal of plasma methotrexate in a patient with acute renal failure2009
- Author(s)
  Nemoto T, Imai C, et al.
- Journal Title
  
  Pediatric Hematology and Oncology 26(7)
  
  Pages: 520-525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] Activated T-cell-mediated immune therapy with a chimeric receptor against CD38 in B-cell non-Hodgkin lymphoma2009
- Author(s)
  Mihara K, Imai C, et al
- Journal Title
  
  J Immunother
  
  Volume: 32 Issue: 7 Pages: 737-43
- DOI
  10.1097/cji.0b013e3181adaff1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] Replicative potential of human natural killer cells.2009
- Author(s)
  Fujisaki H, Imai C, et al.
- Journal Title
  
  British Journal of Haematology 145(5)
  
  Pages: 606-613
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] Replicative potential of human natural killer cells2009
- Author(s)
  Fujisaki H, Kakuda H, Imai C, Mullighan CG, Campana D
- Journal Title
  
  Br J Haematol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790706
[Journal Article] Expansion of Highly Cytotoxic Human Natural Killer Cells for Cancer Cell Therapy.2009
- Author(s)
  Fujisaki H, Imai C, et al.
- Journal Title
  
  Cancer Research 69(9)
  
  Pages: 4010-4017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349
[Journal Article] 小児白血病における最近の話題2008
- Author(s)
  今井千速
- Journal Title
  
  新潟県小児科医会会報 41
  
  Pages: 31-34
- Data Source
  KAKENHI-PROJECT-18790706
[Journal Article] Juvenile myelomonocytic leukemia with less aggressive clinical course and KRAS mutation2008
- Author(s)
  Imamura M, Imai C, et.al.
- Journal Title
  
  Padiatric Blood and Cancer 51(4)
  
  Pages: 569-569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790706
[Journal Article] Juvenile myelomonocytic leukemia with less aggressive clinical course and KRAS mutation2008
- Author(s)
  Imamura M, Imai C, Takachi T, Nemoto T, Tanaka A, Uchiyama M
- Journal Title
  
  Pediatr Blood Cancer 51
  
  Pages: 569-569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790706
[Journal Article] Enhancement of the anti-leukemic activity of cytokine induced killer cells with an anti-CD19 chimeric receptor delivering a 4-1BBζactivating signal2007
- Author(s)
  Mari V, Imai C, et. al.
- Journal Title
  
  Experimental Hematology 35
  
  Pages: 1388-1397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790706
[Journal Article] Enhancement of the anti-leukemic activity of cytokine induced killer cells with an anti-CD19 chimeric receptor delivering a 4-1BB-ζ activatin2007
- Author(s)
  Marin V,Kakuda H,Dander E,Imai C,Campana D,Biondi A,D'Amico G
- Journal Title
  
  Experimental Hematology 35
  
  Pages: 1388-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790706
[Journal Article] Genetic Modification of Natural Killer Cells for Leukemia Therapies.2007
- Author(s)
  Chihaya Imai, et. al.
- Journal Title
  
  Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 6
  
  Pages: 101-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790706
[Journal Article] Genetic Modification of Natural Killer Cells for Leukemia Therapies2007
- Author(s)
  Imai C, Kakuda H, Fujisaki H, Iwamoto S, Campana D
- Journal Title
  
  Anti-Inflammatory Anti-Allergy Agents in Medicinal Chemistry 6
  
  Pages: 101-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790706
[Journal Article] 遺伝子操作により誘導される抗白血病NK細胞2006
- Author(s)
  今井千速
- Journal Title
  
  血液・腫瘍科 52 (4)
  
  Pages: 414-423
- Data Source
  KAKENHI-PROJECT-18790706
[Journal Article] Synthetic messenger RNA as a tool for gene therapy2006
- Author(s)
  Rabinovich PM, Komarovskaya ME, Ye ZJ, Imai C, Campana D, Bahceci E, Weissman SM
- Journal Title
  
  Hum. Gene Ther 17
  
  Pages: 1027-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790706
[Journal Article] 遺伝子操作により誘導される抗白血病NK細胞2006
- Author(s)
  今井千速
- Journal Title
  
  血液・腫瘍科 52
  
  Pages: 414-423
- Data Source
  KAKENHI-PROJECT-18790706
[Journal Article] 抗CD19 レセプターを導入したNK 細胞による白血病・リンパ腫の治療2006
- Author(s)
  今井千速
- Journal Title
  
  臨床免疫 45
  
  Pages: 503-510
- Data Source
  KAKENHI-PROJECT-18790706
[Journal Article] 抗CD19レセプターを導入したNK細胞による白血病・リンパ腫の治療2006
- Author(s)
  今井千速
- Journal Title
  
  臨床免疫 45 (5)
  
  Pages: 503-510
- Data Source
  KAKENHI-PROJECT-18790706
[Patent] キメラ抗原受容体2018
- Inventor(s)
  今井千速、笠原靖史
- Industrial Property Rights Holder
  新潟大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-047242
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16K10015
[Patent] キメラ抗原受容体2016
- Inventor(s)
  今井千速、笠原靖史
- Industrial Property Rights Holder
  今井千速、笠原靖史
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-182078
- Filing Date
  2016-09-16
- Data Source
  KAKENHI-PROJECT-16K10015
[Patent] Chimeric receptors with 4-1BB stimulatory signaling domain2013
- Inventor(s)
  Dario Campana and Chihaya Imai
- Industrial Property Rights Holder
  Dario Campana ,Chihaya Imai, and St. Jude Children's Research Hospital
- Acquisition Date
  2013-03-19
- Overseas
- Data Source
  KAKENHI-PROJECT-21591349
[Patent] Chimeric receptors with 4-1BB stimulatory signaling domain (US Patent)2012
- Inventor(s)
  Campana D and Imai C
- Industrial Property Rights Holder
  Campana D and Imai C
- Industrial Property Rights Type
  特許
- Filing Date
  2012-07-12
- Acquisition Date
  2013-03-19
- Overseas
- Data Source
  KAKENHI-PROJECT-21591349
[Patent] Expansion of NK cells and therapeutic uses thereof2011
- Inventor(s)
  Dario Campana and Chihaya Imai
- Industrial Property Rights Holder
  Dario Campana ,Chihaya Imai, and St. Jude Children's Research Hospital
- Acquisition Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] ALL治療：CCLSG研究からの経験2024
- Author(s)
  今井千速
- Organizer
  小児血液・がん学会セミナーin中部
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] ALL治療における新たな展開2024
- Author(s)
  今井千速
- Organizer
  第3回新潟小児悪性腫瘍研究会学術集会．
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] CAR-T細胞療法の現況と未来2024
- Author(s)
  今井千速
- Organizer
  新潟県輸血フォーラム2024／第37回新潟輸血研究会．
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] 白血病の新規治療の開発2024
- Author(s)
  今井千速
- Organizer
  第99回富山大学医学会学術集会．
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] 小児がん経験者がおとなになるために医療者ができる支援とは：学業支援、就業支援から妊孕能保存まで2024
- Author(s)
  今井千速
- Organizer
  令和5年度富山県小児AYA部会検討会／富山県がん生殖医療ネットワーク推進研修会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] 小児がん医療の最前線2024
- Author(s)
  今井千速
- Organizer
  第82回地域医療連携セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] 急性リンパ性白血病の治療開発2024
- Author(s)
  今井千速
- Organizer
  第340回日本小児科学会北陸地方会．
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] 小児がんの治癒を目指して：分子標的薬や細胞製剤を中心に2023
- Author(s)
  今井千速．
- Organizer
  認定NPO法人ミルフィーユ小児がんフロンティアーズ第9回公開講座
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] 難治性肉腫の制圧を目指して　~化学療法からCAR-T/CAR-NK細胞まで~2023
- Author(s)
  今井千速
- Organizer
  第30回東北地区骨軟部腫瘍研究会共催セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] 小児がん治療の最近の話題2023
- Author(s)
  今井千速
- Organizer
  とやま小児科セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] 脳腫瘍に対するCAR-T細胞療法2023
- Author(s)
  今井千速．
- Organizer
  日本癌治療学会　[領域横断ワークショップ：CAR-T細胞療法の小児がんへの応用：白血病から固形腫瘍まで]
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] 小児血液・がん領域の多施設共同研究（Multi-institutional prospective clinical trials in pediatric hematology and oncology）2023
- Author(s)
  今井千速．
- Organizer
  第56回日本小児内分泌学会学術集会　「シンポジウム5．多機関共同研究のススメ」
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] 小児がん治療の最前線2023
- Author(s)
  今井千速
- Organizer
  黒部市民病院初期研修医向け教育セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] Long-term Follow-up Results of MRD-guided Treatment Protocol for Childhood ALL: CCLSG ALL 2004 study.2023
- Author(s)
  Chihaya Imai, Yasuhiro Ikawa, Yasuto Shimomura, et al.
- Organizer
  The 85th annual meeting of Japanese Society of Hematology.
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] 遺伝子改変T細胞／NK細胞によるがん治療の現状と未来．2022
- Author(s)
  今井千速
- Organizer
  第762回新潟医学会例会シンポジウム「がん免疫療法の現状と未来」新潟市中央区（ウェブカンファレンス）
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] Effects of KIR Gene profiles and NKG2D genotype on NK Cell Functions in Healthy individuals2022
- Author(s)
  Ryosuke Hosokai, Chihaya Imai
- Organizer
  第84回日本血液学会
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] INDUCTION FAILURE IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA IN JAPAN: CCLSG/KYCCSG/JACLS/TCCSG JOINT STUDY.2022
- Author(s)
  Chihaya Imai, et al.
- Organizer
  The 54th Annual Congress of the International Society of Paediatric Oncology (SIOP 2022). Barcelona, Spain
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] CAR-T細胞療法の歴史と展望．2022
- Author(s)
  今井千速．
- Organizer
  CAR-T seminar in Niigata．基調講演　新潟市中央区
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] Generation of chimeric antigen receptor-transduced natural killer cells by using a feeder cell-free system2022
- Author(s)
  Nobuhiro Kubo, Minori Baba, Chansu Shin, Ryosuke Hosokai, Haruko Iwabuchi, Masaru Imamura, Akihiko Saitoh, Chihaya Imai
- Organizer
  第84回日本血液学会
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] 小児がんに対するがん免疫療法．2022
- Author(s)
  今井千速．
- Organizer
  第16回京都地区小児血液腫瘍研究会．京都市
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] 小児がん・がん免疫療法．2022
- Author(s)
  今井千速．
- Organizer
  新潟日報社がん対策事業　~あなたががんになる前に、なった後に、できること~　連続講演「がん医療の今」　新潟市中央区
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] ALLにおけるCAR-T療法：Basic and Beyond2022
- Author(s)
  今井千速
- Organizer
  Novartis CAR-T Web Seminar．東京都
- Invited
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] SJMB-96 based high-dose chemotherapy and CSI within 2 weeks after surgery for medulloblastoma; A Case Series from a Single-Center2022
- Author(s)
  Imamura Masaru, Baba Minori, Kubo Nobuhiro, Shin Changsu, Kasahara Yasushi, Hosokai Ryosuke, Iwabuchi Haruko, Oishi Makoto, Ishikawa Hiroyuki, Imai Chihaya
- Organizer
  第64回日本小児血液・がん学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24297
[Presentation] 再発・難治性腫瘍に対するCAR-T / CAR-NK 細胞療法．2021
- Author(s)
  今井千速
- Organizer
  第1回F-EDCカンファレンス．
- Invited
- Data Source
  KAKENHI-PROJECT-19K08317
[Presentation] NK細胞関連受容体リガンドを標的とした滑膜肉腫細胞に対するCAR-T細胞療法2021
- Author(s)
  村山雄大, 川島寛之, 久保暢大, 笠原靖史, 有泉高志, 生越章, 今井千速
- Organizer
  第36回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K08317
[Presentation] 難治性腫瘍に対する細胞療法：Beyond CAR-T to NK．2021
- Author(s)
  今井千速
- Organizer
  小児血液・がんセミナー in 中部．
- Invited
- Data Source
  KAKENHI-PROJECT-19K08317
[Presentation] 再発・難治性腫瘍に対するCAR-T / CAR-NK 細胞療法2021
- Author(s)
  今井千速
- Organizer
  第1回F-EDCカンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-19K08317
[Presentation] 小児がんの新規治療2021
- Author(s)
  今井千速
- Organizer
  ジャパン・キャンサー・フォーラム2021．
- Invited
- Data Source
  KAKENHI-PROJECT-19K08317
[Presentation] NK細胞機構のCAR開発における利用：CD19-BB-z CARおよびCAR-NKの初期開発の経験から．2020
- Author(s)
  今井千速
- Organizer
  第12回血液疾患免疫療法学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08317
[Presentation] CAR-T療法の現状と課題：さらなる発展に何が必要か2020
- Author(s)
  今井千速
- Organizer
  第18回PBCミーティング
- Invited
- Data Source
  KAKENHI-PROJECT-19K08317
[Presentation] Basic Concepts, History of Development and Future Perspectives in CAR-T Cell Therapy.2020
- Author(s)
  Chihaya Imai.
- Organizer
  第68回日本輸血細胞治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08317
[Presentation] がん免疫療法の基礎と現状．2020
- Author(s)
  今井千速
- Organizer
  社会保険診療報酬支払基金新潟支部学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08317
[Presentation] Chimeric Antigen Receptor (CAR)-T cell therapy for refractory leukemia and lymphoma: From Basic Development to Clinical Outcomes.2019
- Author(s)
  Chihaya Imai
- Organizer
  Japan-Russia Medical Forum 2019 in Irkutsk.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08317
[Presentation] CAR-T細胞療法の基礎と歴史的展望2019
- Author(s)
  今井千速
- Organizer
  第61回日本小児血液・がん学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08317
[Presentation] 小児白血病における遺伝子改変細胞療法2019
- Author(s)
  今井千速
- Organizer
  第149回東京血液腫瘍免疫懇話会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08317
[Presentation] CAR-T療法　~白血病から固形腫瘍へ2019
- Author(s)
  今井千速
- Organizer
  第110回埼玉県小児血液同好会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08317
[Presentation] CAR-T（カーティー）療法：効果の仕組みと今後の展望2019
- Author(s)
  今井千速
- Organizer
  第16回包括的遺伝子医療研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08317
[Presentation] CAR-T療法：開発の歴史と今後の展望．2019
- Author(s)
  今井千速
- Organizer
  第23回新潟悪性リンパ腫研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08317
[Presentation] 小児造血器腫瘍における最新の話題2019
- Author(s)
  今井千速
- Organizer
  九州・山口小児がんフォーラム2019
- Invited
- Data Source
  KAKENHI-PROJECT-16K10015
[Presentation] 小児思春期のがん免疫療法の現状と今後の課題：CAR-T細胞療法を中心に．2019
- Author(s)
  今井千速
- Organizer
  第231回日本小児科学会新潟地方会．
- Invited
- Data Source
  KAKENHI-PROJECT-19K08317
[Presentation] Promising Immunotherapy for Refractory Leukemia in Childhood.2019
- Author(s)
  Chihaya Imai
- Organizer
  The 81st annual meeting of the Japanese Society of Hematology.
- Invited
- Data Source
  KAKENHI-PROJECT-19K08317
[Presentation] NKp44キメラ抗原受容体による新しいがん免疫治療の開発2018
- Author(s)
  笠原靖史、久保暢大、申将守、高地貴行、岩渕晴子、今村勝、今井千速
- Organizer
  第228回日本小児科学会新潟地方会
- Data Source
  KAKENHI-PROJECT-16K10015
[Presentation] Development of novel chimeric antigen receptor targeting PD-1 ligands in cancer cells.2018
- Author(s)
  Chansu Shin, Nobuhiro Kubo, Yasushi Kasahara, Haruko Iwabuchi, Masaru Imamura, Akihiko Saitoh, Chihaya Imai
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10015
[Presentation] キメラ抗原受容体（CAR）による遺伝子改変T細胞療法　-肉腫への応用に向けて　-Chimeric antigen receptor (CAR) gene-modified T cell therapy: Towards treatment of sarcoma2018
- Author(s)
  今井千速
- Organizer
  第91回日本整形外科学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K10015
[Presentation] Superior Activity of NKp44-CAR-T Cells in Comparison with Ex Vivo Expanded Activated NK cells or NKp30-CAR-T cells2018
- Author(s)
  笠原靖史、申将守、久保暢大、岩渕晴子、今村勝、齋藤昭彦、今井千速
- Organizer
  第60回日本小児血液・がん学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10015
[Presentation] Development of novel chimeric antigen receptor targeting PD-1 ligands in Osteosarcoma.2018
- Author(s)
  Chansu Shin, Nobuhiro Kubo, Yasushi Kasahara, Haruko Iwabuchi, Masaru Imamura, Akihiko Saitoh, Chihaya Imai
- Organizer
  50th annual congress of the international society of paediatric oncology
- Data Source
  KAKENHI-PROJECT-16K10015
[Presentation] Development of CAR-T therapy using NKp44 ectodomain for antigen recognition2018
- Author(s)
  笠原靖史、久保暢大、申将守、岩渕晴子、今村勝、今井千速
- Organizer
  第10回血液疾患免疫療法学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10015
[Presentation] 小児固形腫瘍に対するCAR-T 療法の開発2018
- Author(s)
  今井千速
- Organizer
  第14 回北関東小児がんセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16K10015
[Presentation] PD-1 ligands are upregulated after T-cell attack in childhood solid tumors and may become a candidate for CAR-T cell therapy.2018
- Author(s)
  Chansu Shin, Nobuhiro Kubo, Yasushi Kasahara, Haruko Iwabuchi, Masaru Imamura, Akihiko Saitoh, Chihaya Imai
- Organizer
  第60回日本小児血液・がん学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10015
[Presentation] Characteristics and Outcomes of Childhood ALL with ETV6-RUNX1: The CCLSG ALL 2004 Study.2017
- Author(s)
  Imai, Chihaya
- Organizer
  The 59th annual meeting of Japanese Society of Pediatric Hematology and Oncology
- Data Source
  KAKENHI-PROJECT-16K10015
[Presentation] 新潟県における小児専門医療施設を考える：小児科医の立場から2017
- Author(s)
  今井千速．
- Organizer
  第721回新潟医学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K10015
[Presentation] Donor KIR haplotype B exacerbates acute GVHD in HLA-mismatched hematopoietic cell transplantation: A single-center retrospective analysis2016
- Author(s)
  Ryosuke Hosokai, Masayoshi Masuko, Yasuhiko Shibazaki, Akihiko Saitoh, Tatsuo Furukawa, and Chihaya Imai
- Organizer
  European Hematology Association, 21st Congress
- Place of Presentation
  デンマーク・コペンハーゲン
- Year and Date
  2016-06-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461581
[Presentation] キメラ型抗原受容体（CAR）：初期開発の経験から2016
- Author(s)
  今井千速
- Organizer
  東京都小児がん診療連携協議会・TCCSG（東京小児がん研究グループ）共同開催症例検討会
- Place of Presentation
  聖路加国際病院トイスラーホール（東京都中央区）
- Year and Date
  2016-02-06
- Invited
- Data Source
  KAKENHI-PROJECT-25461581
[Presentation] キメラ抗原受容体（CAR）：人工受容体遺伝子を導入したリンパ球による新たながん治療2016
- Author(s)
  今井千速
- Organizer
  第716回新潟医学会
- Place of Presentation
  有壬会館（新潟県新潟市）
- Invited
- Data Source
  KAKENHI-PROJECT-16K10015
[Presentation] キメラ抗原受容体（CAR）の開発：白血病から固形がんへ2016
- Author(s)
  今井千速
- Organizer
  小児血液・がんセミナーin Chiba
- Place of Presentation
  京葉銀行プラザ（千葉県千葉市）
- Invited
- Data Source
  KAKENHI-PROJECT-16K10015
[Presentation] ドナーKIRハプロタイプBはATG不使用同種造血幹細胞移植において重症急性GVHDの危険因子となる可能性がある2014
- Author(s)
  細貝亮介、今井千速、柴崎康彦、増子正義、古川達雄
- Organizer
  第36回日本造血細胞移植学会
- Place of Presentation
  沖縄県宜野湾市
- Data Source
  KAKENHI-PROJECT-25461581
[Presentation] 小児がん・白血病の最近の話題　～整形外科的問題を呈する症例を中心に～2014
- Author(s)
  今井千速
- Organizer
  第2回Niigata OS Meeting
- Place of Presentation
  新潟グランドホテル、新潟市中央区
- Year and Date
  2014-10-22
- Invited
- Data Source
  KAKENHI-PROJECT-25461581
[Presentation] 抗CD19キメラ型受容体とNK細胞体外増幅法の開発2013
- Author(s)
  今井千速
- Organizer
  第26回東北BMT研究会
- Place of Presentation
  宮城県仙台市
- Invited
- Data Source
  KAKENHI-PROJECT-25461581
[Presentation] アロNK細胞輸注療法に向けて～ヒトNK細胞の体外増幅と遺伝子改変法の開発2012
- Author(s)
  今井千速
- Organizer
  第34回日本造血細胞移植学会総会ワークショップ「免疫細胞療法の基礎」
- Place of Presentation
  大阪市
- Year and Date
  2012-02-24
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] Ex Vivo Expansion and Genetic Modification of Human Natural Killer Cells -An approach for treating refractory leukemia and cancer. In Symposium 5: Cellular Therapy2012
- Author(s)
  Imai C
- Organizer
  The 54th Annual Meeting of the Japanese Society of Pediatric Hematology and Oncology
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2012-12-01
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] 白血病治療とNK細胞2012
- Author(s)
  今井千速
- Organizer
  平成24年度JACLS/CCLSG合同夏季セミナー
- Place of Presentation
  福島県耶麻郡北塩原村
- Invited
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] アロNK細胞輸注療法に向けて～ヒトNK細胞の体外増幅と遺伝子改変法の開発(ワークショップ;座長からの招請)2012
- Author(s)
  今井千速
- Organizer
  第34回日本造血細胞移植学会総会
- Place of Presentation
  大阪国際会議場(大阪府)(招待講演)
- Year and Date
  2012-02-24
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] Ex Vivo Expansion and Genetic Modification of Human Natural Killer Cells –An approach for treating refractory leukemia and cancer2012
- Author(s)
  Chihaya Imai
- Organizer
  The 54th Annual Meeting of the Japanese Society of Pediatric Hematology and Oncology, In Symposium 5: Cellular Therapy (International symposium)
- Place of Presentation
  神奈川県横浜市
- Invited
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] Peripheral Blood as a Possible Source of Donor-Derived NK Cells for Ex Vivo Expansion and Genetic Modification for Post-Transplant Cellular Immunotherapy In Cord Blood Recipients.2010
- Author(s)
  Imai C.
- Organizer
  The 52th American Society of Hematology annualmeeting(poster presentation)
- Place of Presentation
  Orlando, Florida, USA
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] Peripheral Blood as a Possible Source of Donor-Derived NK Cells for Ex Vivo Expansion and Genetic Modification for Post-Transplant Cellular Immunotherapy In Cord Blood Recipients2010
- Author(s)
  Imai C
- Organizer
  The 52th American Society of Hematology annual meeting
- Place of Presentation
  Orlando, FL
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] NK細胞の体外増幅と遺伝子改変:難治性腫瘍に対する細胞療法に向けて2010
- Author(s)
  今井千速
- Organizer
  Meet the Professor in NAGOYA
- Place of Presentation
  名古屋市(招待講演)
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] 小児・思春期白血病に対する本邦共通プロトコールの策定2010
- Author(s)
  今井千速
- Organizer
  第658回新潟医学会シンポジウム「血液疾患の治療をめぐる進歩」
- Place of Presentation
  新潟市
- Year and Date
  2010-05-15
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] Myeloablative auto-transplant followed by KIRL-MM RI-CBT for a 10y.o. Boy with NMYC-amp stage IV neuroblastoma.2010
- Author(s)
  Imai C.
- Organizer
  Japan-Korea Neuroblastoma Symposirm
- Place of Presentation
  Nagoya, Japan
- Year and Date
  2010-03-07
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] 造血幹細胞移植とNK細胞2010
- Author(s)
  今井千速
- Organizer
  第16回新潟同種造血幹細胞移植研究会
- Place of Presentation
  新潟市
- Year and Date
  2010-02-05
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] NK 細胞の体外増幅と遺伝子改変:難治性腫瘍に対する細胞療法に向けて2010
- Author(s)
  今井千速
- Organizer
  Meet the Professor in NAGOYA
- Place of Presentation
  名古屋市
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] 造血幹細胞移植とNK細胞(特別講演).2010
- Author(s)
  今井千速
- Organizer
  第16回新潟同種造血幹細胞移植研究会
- Place of Presentation
  新潟県新潟市
- Year and Date
  2010-02-05
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] 臍帯血移植生着後の患者血液からのドナー由来Natural Killer(NK)細胞の体外増幅2009
- Author(s)
  今井千速
- Organizer
  第71回日本血液学会
- Place of Presentation
  京都府京都市
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] NA細胞療法の基礎と展望～NK細胞の体外増幅と遺伝子改変(教育講演)2009
- Author(s)
  今井千速
- Organizer
  第25回日本小児がん学会(がん教育セッション)
- Place of Presentation
  千葉県浦安市
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] 臍帯血移植生着後の患者血液からのドナー由来Natural Killer(NK)細胞の体外増幅2009
- Author(s)
  今井千速
- Organizer
  第71回日本血液学会
- Place of Presentation
  京都市
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] NK細胞療法の基礎と展望～NK細胞の体外増幅と遺伝子改変(教育講演)2009
- Author(s)
  今井千速
- Organizer
  第25回日本小児がん学会,がん教育セッション
- Place of Presentation
  千葉
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-21591349
[Presentation] IL-2 遺伝子導入NK 細胞の生存促進と抗腫瘍効果の持続的発現2008
- Author(s)
  今井千速
- Organizer
  第67回日本血液学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18790706
[Presentation] Interleukin-2 gene transduction in human natural killer cells augments their surval and anti-leukemic capacity(publication only)2008
- Author(s)
  Imai C, et.al.
- Organizer
  The American Society of Hematology 50th Annual Meeting
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-18790706
[Presentation] Simultaneous Use of Histone Deacetylase Inhibitor Valproic Acid Potentiates Natural Killer Cell Cytotoxicity Against T-Lineage Acute Lymphoblastic Leukemia(publication only)2008
- Author(s)
  Takachi T, Imai C, et.al.
- Organizer
  The American Society of Hematology 50th Annual Meeting
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-18790706
[Presentation] IL-2遺伝子導入NK細胞の生存促進と抗腫瘍効果の持続的発現(優秀ポスター演題に選定)2008
- Author(s)
  今井千速, ら
- Organizer
  第70回日本血液学会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-18790706
[Presentation] Interleukin-2 gene transduction in human natural killer cells augments their survival and anti-leukemic capacity (publication only)2008
- Author(s)
  Chihaya Imai, et al
- Organizer
  50th American Society of Hematology Annual Meeting
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-18790706
[Presentation] Activated T Cell-Mediated Immunotherapy with a Chimeric Receptor against CD38 in B-Cell Malignancies2007
- Author(s)
  Mihara K, Imai C, et. al.
- Organizer
  American Society of Hematology
- Place of Presentation
  米国ジョージア州アトランタ
- Year and Date
  2007-12-09
- Data Source
  KAKENHI-PROJECT-18790706
[]
[]

1. IMAMURA Masaru (80464006)

# of Collaborated Projects: 6 results

# of Collaborated Products: 16 results
2. TAKACHI Takayuki (70444164)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
3. SAKIKO Yoshida (30535183)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. IWABUCHI Haruko (60444163)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Saitoh Akihiko (30531389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 渡邉香奈子 (80626094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 三原圭一朗 (90363077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 久保貴紀 (90435751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. TATEISHI Kensuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. SATOU Shinji

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. NATSUMEDA Manabu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. OGOSE Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 伊藤悦朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 柿田明美

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 清水宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 末延聡一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 佐藤聡美

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 中沢洋三

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 岡田正康

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 増子正義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 滝智彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 安藤美樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 安藤純

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 武井佳史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 凌一葦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 高見浩数

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 里見介史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 工藤耕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 土岐力

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Imai Chihaya 今井 千速

IMAI Chihaya 今井 千速

Research Projects

Research Products

Co-Researchers

白血病、脳腫瘍、肉腫、芽腫に幅広く使える大量生産型CAR-NK細胞療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

メモリー様分化誘導を基盤とした多種類のがんに有効なCAR-NK細胞製剤の新規開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel CAR-NK cell therapies that are safe, effective and can be used by anyone at any time

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Novel CAR-T cell with NK cell-like specificity against refractory cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of NK Cell expansion by a novel membrane-bound chimeric cytokine

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigations for Effective Therapies for Human Parechovirus Type 3 Infection

Principal Investigator

Project Period (FY)

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Research Institution

Development of Novel Immunotherapy of Cancer: NKp44-based Chimeric Antigen Receptors and Methods for Ex Vivo NK cell ExpansionPrincipal Investigator

Principal Investigator

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Research Institution

Development of a novel chimeric antigen receptor T cell immunotherapy targeting immune checkpoint molecules

Principal Investigator

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Research Institution

Studies towards development of more effective NK cell therapy: Finding genetic determinants for selection of best NK cell donors and a novel method for transfer of chimeric antigen receptor proteinPrincipal Investigator

Principal Investigator

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Research Institution

Translational Research on the Use of Genetically Modified HumanNatural Killer Cells for Refractory Leukemia.Principal Investigator

Principal Investigator

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Research Institution

Development of a novel therapy against refractory leukemia and lymphoma by using genetically-modified natural killer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

[Book] 今日の治療指針2024版．「小児の特発性血小板減少性紫斑病」1487-1488ページ2024

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 小児血液・腫瘍学 改訂第2版 「CAR-T療法」2022

Author(s)

Total Pages

Imai Chihaya 今井千速

IMAI Chihaya 今井千速

[Book] 小児血液・腫瘍学改訂第2版　「CAR-T療法」2022

[Book] 今日の処方　改訂第6版2019