AOYAMA Chieko 青山智英子

Researcher Number	90420778
Affiliation (based on the past Project Information) *help	2009 – 2018: Dokkyo Medical University, 医学部, 助教
Review Section/Research Field	Principal Investigator Functional biochemistry / Biological pharmacy Except Principal Investigator General medical chemistry
Keywords	Principal Investigator リゾホスファチジン酸 / リゾホスホリパーゼD / シグナル伝達 / 酵素 / 脂質 / 生理活性脂質 / 三量体Gタンパク質 / 脂質代謝 / リゾホスファチジルコリン Except Principal Investigator コレステロール … More / 25-ヒドロキシコレステロール / HMG-CoAレダクターゼ / シチジリルトランスフェラーゼ / ホスホエタノールアミン / オキシステロール / シチジルトランスフェラーゼ / コレステロール25ヒドロキシラーゼ / 25－ヒドロキシコレステロール / Fetal bovine serum / コレステロール25－ヒドロキシラーゼ / ET / コレステロール25ヒドロキシラーぜ / 25ーヒドロキシコレステロール / コレステロール25-ヒドロキシラーゼ / YY1 / HMG-CoA reductase / 25-hydroxycholesterol / Cytidylyltransferase / CTP:phosphoethanolamine / Phosphatidylethanolamine / Yin Yang1 / ホスファチジルエタノールアミン / NF-Y Less

Identification of regulation factor for oxysterol production in FBS and its nobel signal transduction
- Principal Investigator
  
  Sugimoto Hiroyuki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Dokkyo Medical University
Identification of novel transcriptional factors and their roles for homeostasis of lipid composition of cell membrane
- Principal Investigator
  
  Sugimoto Hiroyuki
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Dokkyo Medical University
The regulation of intracellular lysophospholipase D activityPrincipal Investigator
- Principal Investigator
  
  AOYAMA Chieko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Dokkyo Medical University
新規リゾホスホリパーゼDの構造と機能の調節Principal Investigator
- Principal Investigator
  
  青山智英子
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Dokkyo Medical University

All 2018 2017 2016 2015 2014 2013 2011 2010 Other

All Journal Article Presentation

[Journal Article] StarD7 Protein Deficiency Adversely Affects the Phosphatidylcholine Composition, Respiratory Activity, and Cristae Structure of Mitochondria2016
- Author(s)
  Horibata Y, Ando H, Zhang P, Vergnes L, Aoyama C, Itoh M, Reue K, Sugimoto H
- Journal Title
  
  J Biol Chem.
  
  Volume: 291(48) Issue: 48 Pages: 24880-24891
- DOI
  10.1074/jbc.m116.736793
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08158, KAKENHI-PROJECT-15K08284
[Journal Article] Transcriptional suppression of CTP:phosphoethanolamine cytidylyltransferase by 25-hydroxycholesterol is mediated by nuclear factor-Y and Yin Yang 12015
- Author(s)
  Ando H, Aoyama C, Horibata Y, Satou M, Mitsuhashi S, Itoh M, Hosaka K, Sugimoto H
- Journal Title
  
  Biochemical Journal
  
  Volume: 471 Issue: 3 Pages: 369-379
- DOI
  10.1042/bj20150318
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08158, KAKENHI-PROJECT-15K08284, KAKENHI-PROJECT-23590242, KAKENHI-PROJECT-24590358, KAKENHI-PROJECT-25870668
[Journal Article] Muscular dystrophy with large mitochondria associated with mutations in the CHKB gene in three British patients: Extending the clinical and pathological phenotype2013
- Author(s)
  Ros Quinlivan, Satomi Mitsuahashi, Caroline Sewry, Sebahattin Cirak, Chieko Aoyama, David Mooore, Stephen Abbs, Stephanie Robb, Tina Newton, Celia Moss, Daniel Birchall, Hiroyuki Sugimoto, Kate Bushby, Michela Guglieri, Francesco Muntoni, Ichizo Nishino, Volker Straub
- Journal Title
  
  Neuromusucular Disorders
  
  Volume: 23 Issue: 7 Pages: 549-556
- DOI
  10.1016/j.nmd.2013.04.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590358
[Journal Article] The heteromeric G protein subunits Gαq and Gβ1 have lysophospholipase D activity2011
- Author(s)
  Aoyama C, Sugimoto H, Ando H, Yamashita S, Horibata Y, Sugimoto S, Satou M
- Journal Title
  
  Biochem J
  
  Volume: 440 Issue: 2 Pages: 241-250
- DOI
  10.1042/bj20110545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770149, KAKENHI-PROJECT-23770153
[Presentation] オキシステロールによるホスファチジルエタノールアミンおよびコレステロール合成の制御に関与する転写因子の同定と機構解析2018
- Author(s)
  安戸博美、堀端康博、青山智英子、杉本博之
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] StarD7が有する膜貫通領域の同定とミトコンドリア局在およびPC輸送における役割2017
- Author(s)
  堀端康博、安戸博美、青山智英子、佐藤元康、清水泰生、伊藤雅彦、杉本博之
- Organizer
  脂質生化学会
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] 25-hydroxycholesterol suppress the transcription of CTP:phosphoethanolamine cytidylyltransferase and HMG-CoA reductase by inhibiting interaction of p300 and NF-Y and H3K27 acetylation2017
- Author(s)
  Hiromi Ando, Chieko Aoyama, Yasuhiro Horibata, Hiroyuki Sugimoto
- Organizer
  BRIDGING DISCOVERY RESEARCH with THERAPIES
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] The analysis of cellular lysophospholipase D and interacting molecules2017
- Author(s)
  Chieko Aoyama, Hiromi Ando, Satoko Yamashita, Maki Arai, Hiroyuki Sugimoto
- Organizer
  BRIDGING DISCOVERY RESEARCH with THERAPIES
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] StarD7によるミトコンドリアのホスファチジルコリン組成および機能と形態形成の維持2016
- Author(s)
  堀端康博、伊藤雅彦、Peixiang Zhang、Laurent Vergnes、安戸博美、青山智英子、Karen Reue、杉本博之
- Organizer
  日本脂質生化学会
- Place of Presentation
  にぎわい交流会交流会AU(秋田県秋田市)
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] オキシステロールによるホスファチジルエタノールアミンおよびコレステロール合成の制御に関与する新規転写因子の同定と機能解析2016
- Author(s)
  安戸博美、青山智英子、堀端康博、佐藤元康、伊藤雅彦、杉本博之
- Organizer
  日本脂質生化学会
- Place of Presentation
  にぎわい交流会交流会AU(秋田県秋田市)
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] Oxysterol delivertives and transcriptional factors regulating phosphatidylethanolamine and cholesterol biosynthesis2015
- Author(s)
  Hiromi Ando, Chieko Aoyama, Yasuhiro Horibata, Motoyasu Satou, Masahiko Itoh, Hiroyuki Sugimoto
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会・合同会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] The analysis of intracellular lysophospholipase D consist of Galphaq-Gbete complex and other interacting molecules2015
- Author(s)
  Chieko Aoyama, Hiromi Ando, Satoko Yamashita, Hiroyuki Sugimoto
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会・合同会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] The analysis of intracellular lysophospholipase D consist of Galphaq-Gbete complex and other interacting molecules2015
- Author(s)
  Chieko Aoyama, Hiromi Ando, Satoko Yamashita, Hiroyuki Sugimoto
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会・合同会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] Oxysterol delivertives and transcriptional factors regulating phosphatidylethanolamine and cholesterol biosynthesis2015
- Author(s)
  Hiromi Ando, Chieko Aoyama, Yasuhiro Horibata, Motoyasu Satou, Masahiko Itoh, Hiroyuki Sugimoto
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会・合同会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K08284
[Presentation] マウス筋芽細胞株におけるコリンキナーゼの発現2014
- Author(s)
  青山智英子、杉本博之
- Organizer
  日本薬学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] ホスファチジルエタノールアミン合成を制御するオキシステロール代謝産物と転写因子の同定2013
- Author(s)
  安戸博美、青山智英子、山下智子、堀端康博、佐藤元康、三橋里美、杉本博之
- Organizer
  第86回　日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] 細胞内型リゾホスホリパーゼDの局在が活性に及ぼす影響2013
- Author(s)
  青山智英子、三橋里美、山下智子、安戸博美、杉本博之
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23770153
[Presentation] 細胞内リゾホスホリパーゼDの活性調節2013
- Author(s)
  青山智英子,　山下智子,　安戸博美,　杉本博之
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23770153
[Presentation] 細胞内リゾホスホリパーゼDの活性調節2013
- Author(s)
  青山智恵子、山下智子、安戸博美、杉本博之
- Organizer
  日本薬学会　第１３３年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] 細胞内型リゾホスホリパーゼDの局在が活性に及ぼす影響2013
- Author(s)
  青山智英子
- Organizer
  第86回　日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23770153
[Presentation] 細胞内型リゾホスホリパーゼDの局在が活性に及ぼす影響2013
- Author(s)
  青山智英子、三橋里美、安戸博美、山下智子、杉本博之
- Organizer
  第86回　日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] 細胞内ホスホリパーゼDの活性調節2013
- Author(s)
  青山智英子、山下智子、安戸博美、杉本博之
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23770153
[Presentation] 細胞内リゾホスホリパーゼD活性と三量体Gタンパク質との関連2011
- Author(s)
  青山智英子、杉本博之、安戸博美, 山下智子、堀端康博, 杉本さやか、佐藤元康
- Organizer
  第８４回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23770153
[Presentation] Identification of novel lysophospholipase D from rat brain2010
- Author(s)
  青山智英子
- Organizer
  第83回日本生化学会大会第33回日本分子生物学会年会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21790088
[Presentation] Transcriptional suppression of CTP:phosphoethanolamine cytidylyltransferase and HMG-CoA reductase by 25-hydroxycholesterol is mediated by nuclear factor-Y and Yin Yang1.
- Author(s)
  Ando H, Aoyama C, Horibata Y, Sugimoto H.
- Organizer
  Deuel Conference on Lipids
- Place of Presentation
  Monterey, California
- Year and Date
  2015-03-03 – 2015-03-06
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] ホスファチジルエタノールアミン、コレステロールの合成制御におけるオキシステロール代謝産物と新規転写因子の役割
- Author(s)
  安戸博美、青山智英子、保坂公平、杉本博之
- Organizer
  日本脂質生化学会
- Place of Presentation
  大阪
- Year and Date
  2014-06-06 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-24590358
[Presentation] The heterotrimeric G protein subunits Gαq and Gβ1 have lysophospholipase D activity.
- Author(s)
  Aoyama C, Ando H, Sugimoto H.
- Organizer
  Deuel Conference on Lipids
- Place of Presentation
  Monterey, California
- Year and Date
  2015-03-03 – 2015-03-06
- Data Source
  KAKENHI-PROJECT-24590358

1. Sugimoto Hiroyuki (00235897)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
2. ANDO Hiromi (10704885)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
3. SATOU Motoyasu (20418891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. HORIBATA Yasuhiro (80392116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 伊藤雅彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

AOYAMA Chieko 青山 智英子

Research Projects

Research Products

Co-Researchers

Identification of regulation factor for oxysterol production in FBS and its nobel signal transduction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of novel transcriptional factors and their roles for homeostasis of lipid composition of cell membrane

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The regulation of intracellular lysophospholipase D activityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規リゾホスホリパーゼDの構造と機能の調節Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] StarD7 Protein Deficiency Adversely Affects the Phosphatidylcholine Composition, Respiratory Activity, and Cristae Structure of Mitochondria2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transcriptional suppression of CTP:phosphoethanolamine cytidylyltransferase by 25-hydroxycholesterol is mediated by nuclear factor-Y and Yin Yang 12015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Muscular dystrophy with large mitochondria associated with mutations in the CHKB gene in three British patients: Extending the clinical and pathological phenotype2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The heteromeric G protein subunits Gαq and Gβ1 have lysophospholipase D activity2011

Author(s)

Journal Title

DOI

Data Source

[Presentation] オキシステロールによるホスファチジルエタノールアミンおよびコレステロール合成の制御に関与する転写因子の同定と機構解析2018

Author(s)

Organizer

Data Source

[Presentation] StarD7が有する膜貫通領域の同定とミトコンドリア局在およびPC輸送における役割2017

Author(s)

Organizer

Data Source

[Presentation] 25-hydroxycholesterol suppress the transcription of CTP:phosphoethanolamine cytidylyltransferase and HMG-CoA reductase by inhibiting interaction of p300 and NF-Y and H3K27 acetylation2017

Author(s)

Organizer

Data Source

[Presentation] The analysis of cellular lysophospholipase D and interacting molecules2017

Author(s)

Organizer

Data Source

[Presentation] StarD7によるミトコンドリアのホスファチジルコリン組成および機能と形態形成の維持2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] オキシステロールによるホスファチジルエタノールアミンおよびコレステロール合成の制御に関与する新規転写因子の同定と機能解析2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Oxysterol delivertives and transcriptional factors regulating phosphatidylethanolamine and cholesterol biosynthesis2015

Author(s)

Organizer

Place of Presentation

AOYAMA Chieko 青山智英子