MOCHIMARU Hiroshi 持丸博史

Researcher Number	90424168
Affiliation (based on the past Project Information) *help	2014: 慶應義塾大学, 医学部, 特任助教 2010 – 2014: 慶應義塾大学, 医学部, 助教 2008: Keio University, 医学部, 研究員(非常勤) 2007: Keio University, 医学部, 嘱託(非常勤)
Review Section/Research Field	Principal Investigator Ophthalmology
Keywords	Principal Investigator 糖尿病 / 網膜 / 炎症 / 細胞・組織 / 低酸素 / 加齢黄斑変性 / 接着分子 / オメガ3多価不飽和脂肪酸 / EPA / 脈絡膜血管新生

Roles of AMP-activated protein kinase in diabetes-induced retinal inflammation.Principal Investigator
- Principal Investigator
  
  MOCHIMARU Hiroshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Role of HIF1-α in the model of diabetic retinopathyPrincipal Investigator
- Principal Investigator
  
  MOCHIMARU Hiroshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Suppression of Choroidal Neovascularization with omega-3 polyunsaturated fatty acidPrincipal Investigator
- Principal Investigator
  
  MOCHIMARU Hiroshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University

All 2015 2014 2013 2012 2011 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Association of macular pigment optical density with serum concentration of oxidized low-density lipoprotein in healthy adults.2015
- Author(s)
  Nagai N, Izumi-Nagai K, Suzuki M, Shinoda H, Koto T, Uchida A, Mochimaru H, Tomita Y, Miyake S, Kobayashi S, Sasaki M, Tsubota K, Ozawa Y.
- Journal Title
  
  Retina
  
  Volume: 35(4) Issue: 4 Pages: 820-826
- DOI
  10.1097/iae.0000000000000382
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592648, KAKENHI-PROJECT-24592649, KAKENHI-PROJECT-15K10903, KAKENHI-PROJECT-15K20284, KAKENHI-PROJECT-26893100
[Journal Article] Association of Maternal Age to Development and Progression of Retinopathy of Prematurity in Infants of Gestational Age under 33 Weeks.2014
- Author(s)
  Uchida A, Miwa M, Shinoda H, Koto T, Nagai N, Mochimaru H, Tomita Y, Sasaki M, Ikeda K, Tsubota K, Ozawa Y
- Journal Title
  
  J Ophthalmol.
  
  Volume: 2014 Pages: 187929-187929
- DOI
  10.1155/2014/187929
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592647, KAKENHI-PROJECT-24592648, KAKENHI-PROJECT-24592649
[Journal Article] Ozawa Predictive factors for non-responders to intravitreal ranibizumab treatment in age-related macular degeneration2014
- Author(s)
  Suzuki M, Nagai N, Izumi-Nagai K, Shinoda H, Koto T, Uchida A, Mochimaru H, Yuki K, Sasaki M, Tsubota K
- Journal Title
  
  Br J Ophthalmol
  
  Volume: 98 Issue: 9 Pages: 7-7
- DOI
  10.1136/bjophthalmol-2013-304670
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23592588, KAKENHI-PROJECT-24592647, KAKENHI-PROJECT-24592648, KAKENHI-PROJECT-24592649
[Journal Article] Vitrectomy for myopic foveoschisis with internal limiting membrane peeling and no gas tamponade.2013
- Author(s)
  Uchida A, Shinoda H, Koto T, Mochimaru H, Nagai N, Tsubota K, Ozawa Y
- Journal Title
  
  Retina.
  
  Volume: 34 Issue: 3 Pages: 455-460
- DOI
  10.1097/iae.0b013e3182a0e477
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592588, KAKENHI-PROJECT-24592647, KAKENHI-PROJECT-24592648, KAKENHI-PROJECT-24592649
[Journal Article] Detection of Early Visual Impairment in Patients with Epiretinal Membrane.2013
- Author(s)
  Nishi Y, Shinoda H, Uchida A, Koto T, Mochimaru H, Nagai N, Tsubota K, Ozawa Y.
- Journal Title
  
  Acta Ophthalmologica
  
  Volume: Epub ahead of print Issue: 5 Pages: 1-5
- DOI
  10.1111/aos.12060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592588, KAKENHI-PROJECT-24592647, KAKENHI-PROJECT-24592648, KAKENHI-PROJECT-24592649
[Journal Article] Resveratrol Prevents Ocular Inflammation in Endotoxin-Induced Uveitis via Inhibiting Oxidative Damage and Nuclear Factor-{kappa}B Activation2009
- Author(s)
  Kubota S, Kurihara T, Mochimaru H, Satofuka S, Noda K, Ozawa Y, Oike Y, Ishida S, Tsubota K
- Journal Title
  
  Invest Ophthalmol Vis Sci
- Data Source
  KAKENHI-PROJECT-19791291
[Journal Article] Suppression of alkali burn-induced corneal neovascularization by dendritic cell vaccination targeting VEGF receptor 22008
- Author(s)
  Mochimaru H, Usui T, Yaguchi T, Nagahama Y, Hasegawa G, Usui Y, Shimmura S, Tsubota K, Amano S, Kawakami Y, Ishida S
- Journal Title
  
  Invest Ophthalmol Vis Sci 49(5)
  
  Pages: 2172-2177
- Data Source
  KAKENHI-PROJECT-19791291
[Journal Article] Eicosapentaenoic Acid is anti-inflammatory in preventing choroidalneovascularization in mice2007
- Author(s)
  Koto T, Mochimaru H., et. al.
- Journal Title
  
  Investigative Ophthalmology & Visual Sciences 48(9)
  
  Pages: 4328-4334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791291
[Journal Article] Suppression of choroidal neovascularization by dendritic cell vaccination targeting VEGFR22007
- Author(s)
  Mochimaru H, Nagai N, Hasegawa G, Kudo-Saito C, Yaguchi T, Usui Y, Kurihara T,Koto T, Satofuka S, Shinoda H, Ozawa Y, Tsubota K, Kawakami Y, Ishida S
- Journal Title
  
  Invest Ophthalmol Vis Sci 48(10)
  
  Pages: 4795-4801
- Data Source
  KAKENHI-PROJECT-19791291
[Journal Article] Eicosapentaenoic acid is anti-inflammatory in preventing choroidal neovascularization in mice2007
- Author(s)
  Koto T, Nagai N, Mochimaru H, Kurihara T, Izumi-Nagai K, Satofuka S, Shinoda H, Noda K, Ozawa Y, Inoue M, Tsubota K, Oike Y, Ishida S
- Journal Title
  
  InvestOphthalmol Vis Sci 48(9)
  
  Pages: 4328-4334
- Data Source
  KAKENHI-PROJECT-19791291
[Presentation] 狭義加齢黄斑変性に対するpro re nateによるラニビズマブ硝子体注射.2013
- Author(s)
  3. 鈴木美砂, 永井紀博, 永井香奈子, 篠田肇, 内田敦郎, 厚東隆志, 持丸博史, 富田洋平, 佐々木真理子, 坪田一男, 小沢洋子.
- Organizer
  第67回日本臨床眼科学会
- Place of Presentation
  パシフィコ横浜　神奈川県　横浜市
- Data Source
  KAKENHI-PROJECT-24592649
[Presentation] 新規過活動膀胱治療薬ミラベグロン投与後早期に発症した網膜静脈分子閉塞症の一例2012
- Author(s)
  持丸博史、前田高宏、厚東隆志、内田敦郎、永井紀博、篠田肇、坪田一男、小沢洋子
- Organizer
  第66回日本臨床眼科学会総会
- Place of Presentation
  京都府京都市
- Data Source
  KAKENHI-PROJECT-24592649
[Presentation] 内境界膜剥離併用硝子体手術で中心窩網膜分離が改善したX染色体性若年性網膜分離の1例2011
- Author(s)
  川島弘彦, 篠田肇, 持丸博史, 厚東隆志, 永井紀博, 小沢洋子, 坪田一男
- Organizer
  第50回日本網膜硝子体学会総会
- Place of Presentation
  東京,東京国際フォーラム
- Year and Date
  2011-12-02
- Data Source
  KAKENHI-PROJECT-22791687
[Presentation] 内境界膜剥離併用硝子体手術で中心窩網膜分離が改善したX染色体性若年性網膜分離の1例2011
- Author(s)
  川島弘彦、持丸博史, ら
- Organizer
  第50回日本網膜硝子体学会総会
- Place of Presentation
  東京国際フォーラム(東京都)
- Data Source
  KAKENHI-PROJECT-22791687
[Presentation] Suppression of Alkali Burn-Induced Corneal Neovascularization by Dendric Cell Vaccination Targeting VEGF Receptor22008
- Author(s)
  Usui T, Mochimaru H, Usui S, Yamaguchi S, Amano S, Tsubota K, Kawakami Y, Ishida S
- Organizer
  The Association for Research in Vision and Ophthalmology(ARVO)
- Place of Presentation
  Florida, USA
- Year and Date
  2008-04-27
- Data Source
  KAKENHI-PROJECT-19791291
[Presentation] Involvement of Hyarulonan With Choroidal Neovascularization2008
- Author(s)
  Mochimaru H, Takahashi E, Tsubota K, Saya H, Ishida S
- Organizer
  The Association for Research in Vision and Ophthalmology(ARVO)
- Place of Presentation
  Florida, USA
- Year and Date
  2008-04-27
- Data Source
  KAKENHI-PROJECT-19791291
[Presentation] Immunization of mice with dendritic cells primed with epitope peptide derived from VEGF receptor 2 supresses choroidal neovascularization2007
- Author(s)
  Mochimaru H, Nagai N, Hasegawa G, Kudo-Saito C, Yaguchi T, Satofuka S, Ozawa Y, Tsubota K, Kawakami Y, Ishida S
- Organizer
  The Association for Research in Vision and Ophthalmology (ARVO), Annual meeting
- Place of Presentation
  Florida, U.S.A
- Data Source
  KAKENHI-PROJECT-19791291
[Presentation] Anti-inflammatory effect of eicosapentaenoic acid on diabetic retina in vivo and cytokine expression in vitro2007
- Author(s)
  Koto T, Nagai N, Mochimaru H, Izumi-Nagai K, Satofuka S, Shinoda H, Noda K, Kurihara T, Ozawa Y, Inoue M, Tsubota K, Ishida S
- Organizer
  The Association for Research in Vision and Ophthalmology (ARVO), Annual meeting
- Place of Presentation
  Florida, U.S.A
- Data Source
  KAKENHI-PROJECT-19791291
[Presentation] Lutein Inhibits Choroidal Neovascularization in Mice2007
- Author(s)
  Izumi-Nagai K, Nagai N, Satofuka S, Koto T, Mochimaru H, Tsubota K, Ohgami K, Ohno S, Ishida S
- Organizer
  The Association for Research in Vision and Ophthalmology (ARVO), Annual meeting
- Place of Presentation
  Florida, U.S.A
- Data Source
  KAKENHI-PROJECT-19791291
[Presentation] エイコサペンタエン酸の摂取による実験的脈絡膜血管新生の抑制効果2007
- Author(s)
  厚東隆志,持丸博史et al
- Organizer
  第41回日本眼炎症学会
- Place of Presentation
  東京
- Year and Date
  2007-07-06
- Data Source
  KAKENHI-PROJECT-19791291
[Presentation] 多局所網膜電図を施行したfocal choroidal excavation 3例
- Author(s)
  内田敦郎、富田洋平、持丸博史、栗原俊英、永井紀博、篠田肇、小沢洋子、坪田一男.
- Organizer
  第53回日本網膜硝子体学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2014-11-28 – 2014-11-30
- Data Source
  KAKENHI-PROJECT-24592649
[Presentation] 網膜静脈分枝閉塞症に伴う黄斑浮腫に対するラニビズマブ投与の３カ月治療成績.
- Author(s)
  栗原俊英、永井紀博、鈴木美砂、内田敦郎、持丸博史、富田洋平、篠田肇、坪田一男、小沢洋子.
- Organizer
  第68回日本臨床眼科学会
- Place of Presentation
  神戸国際展示場（兵庫県神戸市）
- Year and Date
  2014-11-13 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-24592649
[Presentation] 治療抵抗性の加齢黄斑変性に対するアフリベルセプトスイッチング症例の1年成績
- Author(s)
  永井紀博、鈴木美砂、持丸博史、富田洋平、内田敦郎、栗原俊秀、佐々木真理子、篠田肇、坪田一男、小沢洋子.
- Organizer
  第53回日本網膜硝子体学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2014-11-28 – 2014-11-30
- Data Source
  KAKENHI-PROJECT-24592649
[Presentation] Associations of Serum Lipids with Macular Morphology in Patients without Diabetic Macular Edema.
- Author(s)
  Sasaki M, Kawashima M, Kawasaki R, Kawai M, Uchida A, Koto T, Mochimaru H, Shinoda H, Jie Jin Wang, Tsubota K, Ozawa Y.
- Organizer
  Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting
- Place of Presentation
  Washington State Convention & Trade Center Seattle, USA,
- Data Source
  KAKENHI-PROJECT-24592649
[Presentation] Baseline characteristics and response to intravitreal ranibizumab therapy for age-related macular degeneration.
- Author(s)
  Suzuki M, Nagai N, Izumi-Nagai K, Shinoda H, Koto T, Uchida A, Mochimaru H, Yuki K, Tsubota K, Ozawa Y.
- Organizer
  Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting
- Place of Presentation
  Washington State Convention & Trade Center Seattle, USA,
- Data Source
  KAKENHI-PROJECT-24592649
[Presentation] A Case of Corneal Infiltration after intravitreal Injection of Bevacizumab.
- Author(s)
  Ozawa N, Nagai N, Mochimaru H, Tsubota K, Ozawa Y.
- Organizer
  World Ophthalmology Congress 2014
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2014-04-02 – 2014-04-06
- Data Source
  KAKENHI-PROJECT-24592649
[Presentation] 無治療のポリープ状脈絡膜血管症に対するラニビズマブ、アフリベルセプトの作用
- Author(s)
  伊吹麻里、永井紀博、鈴木美砂、富田洋平、持丸博史、栗原俊英、内田敦郎、篠田肇、坪田一男、小沢洋子.
- Organizer
  第68回日本臨床眼科学会
- Place of Presentation
  神戸国際展示場（兵庫県神戸市）
- Year and Date
  2014-11-13 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-24592649

1. KOTO Takashi (60464814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. NAGAI Norihiro (10327611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. OZAWA Yoko (90265885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
4. SHINODA Hajime

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

MOCHIMARU Hiroshi 持丸 博史

Research Projects

Research Products

Co-Researchers

Roles of AMP-activated protein kinase in diabetes-induced retinal inflammation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of HIF1-α in the model of diabetic retinopathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Suppression of Choroidal Neovascularization with omega-3 polyunsaturated fatty acidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Association of macular pigment optical density with serum concentration of oxidized low-density lipoprotein in healthy adults.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association of Maternal Age to Development and Progression of Retinopathy of Prematurity in Infants of Gestational Age under 33 Weeks.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ozawa Predictive factors for non-responders to intravitreal ranibizumab treatment in age-related macular degeneration2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vitrectomy for myopic foveoschisis with internal limiting membrane peeling and no gas tamponade.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection of Early Visual Impairment in Patients with Epiretinal Membrane.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Resveratrol Prevents Ocular Inflammation in Endotoxin-Induced Uveitis via Inhibiting Oxidative Damage and Nuclear Factor-{kappa}B Activation2009

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of alkali burn-induced corneal neovascularization by dendritic cell vaccination targeting VEGF receptor 22008

Author(s)

Journal Title

Data Source

[Journal Article] Eicosapentaenoic Acid is anti-inflammatory in preventing choroidalneovascularization in mice2007

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of choroidal neovascularization by dendritic cell vaccination targeting VEGFR22007

Author(s)

Journal Title

Data Source

[Journal Article] Eicosapentaenoic acid is anti-inflammatory in preventing choroidal neovascularization in mice2007

Author(s)

Journal Title

Data Source

[Presentation] 狭義加齢黄斑変性に対するpro re nateによるラニビズマブ硝子体注射.2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 新規過活動膀胱治療薬ミラベグロン投与後早期に発症した網膜静脈分子閉塞症の一例2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 内境界膜剥離併用硝子体手術で中心窩網膜分離が改善したX染色体性若年性網膜分離の1例2011

Author(s)

Organizer

MOCHIMARU Hiroshi 持丸博史