ZHANG Guo-Xing 張国興

… Alternative Names

ZHANG Guo-xing 張國興

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Researcher Number	90444728
Affiliation (based on the past Project Information) *help	2009: 奈良県立医科大学, 医学部・第二生理学, 助教 2008: Nara Medical University, 医学部, 助教 2007: Kagawa University, 医学部, 助教 2007: 香川大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator General pharmacology Except Principal Investigator Functional basic dentistry / General pharmacology
Keywords	Principal Investigator Rap-1 / mitogen-activated protein kinase / 酸化ストレス / 心肥大 / アドレナリン作用薬 / アンジオテンシン / alDha-, beta adrenergic receptor / cardiac hypertrophy / ATIR / alpha-, beta adrenergic receptor … More / Cardiac Hypertrophy / MAPK / AT1R / ARB … More Except Principal Investigator 可溶性RANKL / 遺伝子導入 / siRNA / RAW264.7 / NFAT / RCAN1 / RCAN / 骨吸収 / カルシニューリン / カルシウム / 破骨細胞 / シグナル伝達 / 骨代謝 / 血管平滑筋 / ミトコンドリア / MAPキナーゼ / 活性酸素 / アンジオテンシン / 一酸化窒素合成酵素 / 酸化ストレス / 高血圧 Less

Role of regulators of calcineurin 1, RCAN1 as an endogenous calcineur in inhibitor, on osteoolast differentiation
- Principal Investigator
  
  OBATA Koji
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi Gakuin University
Role of nitric oxide in reactive oxygen species-dependent intracellular signal transduction in cardiovascular tissue
- Principal Investigator
  
  KIMURA Shoji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kagawa University
Ligand independent activation of angiotensin II receptorPrincipal Investigator
- Principal Investigator
  
  ZHANG Guo-xing
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nara Medical University
  Kagawa University

All 2010 2009 2008 2007

All Journal Article Presentation Book

[Book] D-allose suppresses development of hypertension in salt-loaded spontaneously hypertensive rats(RARE SUGARS II, Edited by Asada Y, Kawanami Y, Tajima S)2008
- Author(s)
  Zhang GX, Nagai Y, Fujisawa Y, Nishiyama A, Kimura S.
- Publisher
  Art-Printing Co. Ltd.
- Data Source
  KAKENHI-PROJECT-19590250
[Journal Article] Cardioprotective effects of a novel calpain inhibitor SNJ-1945 for reperfusion injury after cardioplegic cardiac arrest2010
- Author(s)
  Yoshikawa Y, Zhang GX, Obata K, Ohga Y, Matsuyoshi H, Taniguchi S, Takaki M
- Journal Title
  
  Am J Physiol Heart Circ Physiol 298(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791366
[Journal Article] Inhibition of cytochrome c release by 10-N-nonyl acridine orange, a cardiolipin-specific dye, during myocardial ischemia-reperfusion in the rat2010
- Author(s)
  Zhang GX, Kimura S, Murao K, Obata K, Matsuyoshi H, Takaki M
- Journal Title
  
  Am J Physiol Heart Circ Physiol 298(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791366
[Journal Article] A 5-HT(4)-receptor activation-induced neural plasticity enhances in vivo reconstructs of enteric nerve circuit insult2010
- Author(s)
  Matsuyoshi H, Kuniyasu H, Okumura M, Misawa H, Katsui R, Zhang GX, Obata K, Takaki M
- Journal Title
  
  Neurogastroenterol Motil (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791366
[Journal Article] Inhibition of cytochrome c release by 10-N-nonyl acridine orange, acardiolipin-specific dye, during myocardial ischemia-reperfusion in the rat.2010
- Author(s)
  Zhang GX, et al.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 298(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791366
[Journal Article] Role of euronal NO synthase in regulating vascular superoxide levels and mitogen-activated protein kinase phosphorylation2009
- Author(s)
  Zhang GX, Kimura S, Murao K, Shimizu J, Matsuyoshi H, Takaki M
- Journal Title
  
  Cardiovasc Res 81
  
  Pages: 389-99
- Data Source
  KAKENHI-PROJECT-19790190
[Journal Article] Role of neuronal NO synthase in regulating vascular superoxide levels and mitogen-activated protein kinase phosphorylatlon.2009
- Author(s)
  Zhang, et al.
- Journal Title
  
  Cardiovasc Res. 81
  
  Pages: 389-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590250
[Journal Article] Left ventricular function of isoproterenol-induced hypertrophied rat hearts perfused with blood: mechanical work and energetics2009
- Author(s)
  Nakajima-Takenaka C, Zhang GX, Obata K, Tohne K, Matsuyoshi H, Nagai Y, Nishiyama A, Takaki M
- Journal Title
  
  Am J Physiol Heart Circ Physiol 297(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791366
[Journal Article] Role of neuronal NO synthase in regulating vascular superoxide levels and mitogen-activated protein kinase phosphorylation2009
- Author(s)
  Guo-Xing Zhang
- Journal Title
  
  Cardiovascular Research 81
  
  Pages: 389-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790190
[Journal Article] Role of neuronal NO synthase in regulating vascular superoxide levels and mitogen-activated protein kinase phos2009
- Author(s)
  Zhang GX, Kimura S, Murao K, Shimizu J, Matsuyoshi H, Takaki M.
- Journal Title
  
  Cardiovasc Res 81
  
  Pages: 389-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590250
[Journal Article] The opposite roles of nNOS in cardiac ischemia-reperfusion-induced injury and in ischemia preconditioning-induced cardioprotection in mice.2009
- Author(s)
  Lu XM, Zhang GX, Yu YQ, Kimura S, Nishiyama A, Matsuyoshi H, Shimizu J, Takaki M.
- Journal Title
  
  J Physiol Sci.
- NAID
  10025218967
- Data Source
  KAKENHI-PROJECT-19590250
[Journal Article] Possible involvement of Rho-kinase in aldosterone-induced vascular smooth muscle cell remodeling2008
- Author(s)
  Miyata K, Hitomi H, Guo P, Zhang GX, Kimura S, Kiyomoto H, Hosomi N, Kagami S, Kohno M, Nishiyama A
- Journal Title
  
  Hypertens Res 31
  
  Pages: 1407-13
- Data Source
  KAKENHI-PROJECT-19790190
[Journal Article] Aldosterone induces myofibroblastic transdifferentiation and collagen gene expression through the Rho-kinase dependent signaling pathway in rat mesangial cells2008
- Author(s)
  Diah S, Zhang GX, Nagai Y, Zhang W, Gang L, Kimura S, Hamid MRWA, Tamiya T, Nishiyama A, Hitomi H.
- Journal Title
  
  Exp Cell Res 314
  
  Pages: 3654-3662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590250
[Journal Article] Aldosterone induces myofibroblastic transdifferentiation and collagen gene expression through the Rho-kinase dependent signaling pathway in rat mesangial cells2008
- Author(s)
  Diah S, Zhang GX, Nagai Y, Zhang W, Gang L, Kimura S, Hamid MR, Tamiya T, Nishiyama A, Hitomi H
- Journal Title
  
  Exp Cell Res 314
  
  Pages: 3654-62
- Data Source
  KAKENHI-PROJECT-19790190
[Journal Article] Role of mitochondria in angiotensn II-induced reactive oxygen species and mitogen-activated protein kinase activation2007
- Author(s)
  Zhang GX, Lu XM, Kimura S, Nishiyama A.
- Journal Title
  
  Cardiovasc Res 76
  
  Pages: 204-212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590250
[Journal Article] Role of mitochondria in angiotensin II-induced reactive oxygen species and mitogen-activated protein kinase activation2007
- Author(s)
  Zhang GX, Lu XM, Kimura S, Nishiyama A
- Journal Title
  
  Cardiovasc Res 76
  
  Pages: 204-12
- Data Source
  KAKENHI-PROJECT-19790190
[Journal Article] R ole of AT1 receptor in isoproterenol-induced cardiac hypertrophy and oxidative stress in mice2007
- Author(s)
  6.Zhang GX, Ohmori K, Nagai Y, Fujisawa Y, Nishiyama A, Abe Y, Kimura S
- Journal Title
  
  J Mol Cell Cardiol 42
  
  Pages: 804-11
- Data Source
  KAKENHI-PROJECT-19790190
[Journal Article] Role of AT1 receptor in isoproterenol-induced cardiac hypertrophy and oxidative stress in mice2007
- Author(s)
  Zhang, et. al.
- Journal Title
  
  J Mol Cell Cardiol 42
  
  Pages: 804-811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590250
[Journal Article] Role of mitochondria in angiotensn Il-induced reactive oxygen species andmitoaen-activated protein kinase activation.2007
- Author(s)
  Zhang, et. al.
- Journal Title
  
  Cardiovasc Res. 76
  
  Pages: 204-212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790190
[Journal Article] Role of ATI receptor in isoproterenol-induced cardiac hypertrophy andoxidative stress in mice.2007
- Author(s)
  Zhang, et. al.
- Journal Title
  
  J Mol Cell Cardiol. 42
  
  Pages: 804-811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790190
[Journal Article] Involvement of endogenous nitric oxide in angiotensin II-induced activation of vascular mitogen-activated protein kinases2007
- Author(s)
  5.Zhang GX, Nagai Y, Nakagawa T, Miyanaka H, Fujisawa Y, Nishiyama A, Izuishi K, Ohmori K, Kimura S
- Journal Title
  
  Am J Physiol Heart Circ Physiol 293
- Data Source
  KAKENHI-PROJECT-19790190
[Journal Article] Role of AT1 receptor in isoproterenol-induced cardiac hypertrophy and oxidative stress in mi2007
- Author(s)
  Zhang GX, Ohmori K, Nagai Y, Fujisawa Y, Nishiyama A, Abe Y, Kimura S
- Journal Title
  
  J Mol Cell Cardiol 42
  
  Pages: 804-811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590250
[Journal Article] Involvement of endogenous nitric oxide in Angiotensin Il-induced activation of vascular mitoeen-activated protein kinases.2007
- Author(s)
  Zhang, et. al.
- Journal Title
  
  AmJ Physiol Heart Circ Physiol 293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790190
[Journal Article] Involvement of endogenous nitric oxide in angiotensin II-induced activation of vascular mitogen-activated protein kinases2007
- Author(s)
  Zhang GX, Nagai Y, Nakagawa T, Miyanaka H, Fujisawa Y, Nishiyama A, Izuishi K, Ohmori K, Kimura S.
- Journal Title
  
  Am J Physiol Heart Circ Physiol 293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590250
[Journal Article] Involvement of endogenous nitric oxide in Angiotensin II-induced activation of vascular mitogen-activated protein kinases2007
- Author(s)
  Zhang, et. al.
- Journal Title
  
  Am J Physiol Heart Circ Physiol 293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590250
[Journal Article] Role of mitochondria angiotensn II-induced reactive oxygen species and mitogen-activated protein kinase activation2007
- Author(s)
  Zhang, et. al.
- Journal Title
  
  Cardiovasc Res 76
  
  Pages: 204-212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590250
[Presentation] Role of nNOS in basal and angiotensin II-induced vascular O2 generation and MAPK phosphorylation2009
- Author(s)
  Guo-Xing Zhang
- Organizer
  第19回日本病態生理学会大会
- Place of Presentation
  所沢
- Data Source
  KAKENHI-PROJECT-19790190
[Presentation] Possible mechanisms of AT1 receptor blcckade on β-adrenergic receptor stimulation-induced cardiac hypertrophy2009
- Author(s)
  Guo-Xing Zhang, Shoji Kimura, Koji Murao, Koji Ohata, Hiroko Matsuyoshi, Miyako Takah
- Organizer
  第102回近畿生理学談話会
- Place of Presentation
  大阪
- Year and Date
  2009-12-13
- Data Source
  KAKENHI-PROJECT-20791366
[Presentation] Overexpression of calmodulin in cardiomyocytes induces cardiac hypertrophy by a calcineudn-dependet pathway2009
- Author(s)
  Obta K: Guo-Xing Zhang, Hiroko Matsuyoshi, Mitsuhiro Yokota Miyako Takaki
- Organizer
  第102回近畿生理学談話会
- Place of Presentation
  大阪
- Year and Date
  2009-12-13
- Data Source
  KAKENHI-PROJECT-20791366
[Presentation] イソプロテレノール誘導肥大心の左心室心筋スライスのカルシウムトランジェントの変化2009
- Author(s)
  服部宇孜・竹下大輔・張国興・盤二・松吉ひろ子・三澤裕美・高木都
- Organizer
  第102回近畿生理学談話会
- Place of Presentation
  大阪
- Year and Date
  2009-12-13
- Data Source
  KAKENHI-PROJECT-20791366
[Presentation] Role of nNOS in basal and angiotensin II-induced vascular O_2 generation and MAPK nhosohorvlation2009
- Author(s)
  Guo-Xing Zhang
- Organizer
  第19回日本病態生理学会大会
- Place of Presentation
  所沢
- Year and Date
  2009-01-24
- Data Source
  KAKENHI-PROJECT-19790190
[Presentation] Opposite roles of nNOS in cardiac ischemia reperfusion-induced injury and in ischemia preconditioning -induced cardioprotection in mice2008
- Author(s)
  Guo-Xing Zhang
- Organizer
  第101回近畿生理学談話会
- Place of Presentation
  国立循環器病センター
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-19790190
[Presentation] Opposite roles of nNOS in cardiac ischemia reperfusion-induced injury and in ischemia preconditioning-induced cardioprotection in mice2008
- Author(s)
  Guo-Xing Zhang
- Organizer
  第101回近畿生理学談話会
- Place of Presentation
  大阪
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-19790190
[Presentation] Involvement of endogenous nitric oxide in angiotensin II-induced activation of vascular mitogen-activated protein kinases2007
- Author(s)
  Zhang, et. al.
- Organizer
  9^<th> Intemational Symposium on Hypertension and Related Diseases
- Place of Presentation
  Beijing,Caina
- Data Source
  KAKENHI-PROJECT-19590250
[Presentation] Involvement of endogenous nitric oxide in Angiotensin II-induced activation of vascular mitogenactivated protein kinases2007
- Author(s)
  Zhang, et. al.
- Organizer
  第30回日本高血圧学会総会
- Place of Presentation
  宜野湾
- Data Source
  KAKENHI-PROJECT-19590250
[Presentation] Involvement of endogenous nitric oxide in Angiotensin II-induced activation of vascular mitogen-activated protein kinases2007
- Author(s)
  Zhang GX et.al.
- Organizer
  第30回日本高血圧学会総会
- Place of Presentation
  宜野湾
- Year and Date
  2007-10-25
- Data Source
  KAKENHI-PROJECT-19590250
[Presentation] Effects of 10-N-nonyl acridine orange(NAO)on ischemic/reperfusion injury in rat heart2007
- Author(s)
  張国興, 他
- Organizer
  第7回日本NO学会学術集会
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-19590250
[Presentation] NAO(10-N-nonyl acridineorang)は心筋虚血再還流時のミトクロムC漏出を抑制する2007
- Author(s)
  張国興
- Organizer
  第80回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19790190
[Presentation] Involvement of endogenous nitric oxide in angiotensin II-induced activation of vascular mitogen-activated protein kinases2007
- Author(s)
  Zhang GX et.al.
- Organizer
  第9回日中高血圧シンポジウム
- Place of Presentation
  Beijin, China
- Year and Date
  2007-11-11
- Data Source
  KAKENHI-PROJECT-19590250
[Presentation] Effects of 1 0-N-nonyl acridine orange (NAO)on ischemic/reperfiision injury in rat heart2007
- Author(s)
  張国興, 他
- Organizer
  第7回日本NO学会学術集会
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-19790190
[Presentation] Involvement of endogenous nitric oxide in nangiotensin II-induced activation of vascular mitogen- activated protein kinases2007
- Author(s)
  Guo-Xing Zhang
- Organizer
  第30回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-19790190
[Presentation] Involvement of endogenous nitric oxide in angiotensin Il-induced activation of vascular mitogen-activated protein kinases.2007
- Author(s)
  Zhang, et. al.
- Organizer
  9th International Symposium on Hypertensionand Related Diseases
- Place of Presentation
  Beijing,Caina
- Data Source
  KAKENHI-PROJECT-19790190
[Presentation] Involvement of endogenous nitric oxide in Angiotensin Il-induced activation of vascular mitogen-activated protein kinases.2007
- Author(s)
  Zhang, et. al.
- Organizer
  第30回日本高血圧学会総会
- Place of Presentation
  宜野湾
- Data Source
  KAKENHI-PROJECT-19790190

1. KIMURA Shoji (30253264)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. NISHIYAMA Akira (10325334)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. OHMORI Koji (00263913)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. 宮武明 (80211598)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NAGAI Yukiko (30335864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. OBATA Koji (40378229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 高木都 (00033358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. 松吉ひろ子 (10448772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
9. 横田充弘 (50201851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 野間貴久

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 永井由起子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 藤澤良秀

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

ZHANG Guo-Xing 張 国興

ZHANG Guo-xing 張 國興

Research Projects

Research Products

Co-Researchers

Role of regulators of calcineurin 1, RCAN1 as an endogenous calcineur in inhibitor, on osteoolast differentiation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of nitric oxide in reactive oxygen species-dependent intracellular signal transduction in cardiovascular tissue

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ligand independent activation of angiotensin II receptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] D-allose suppresses development of hypertension in salt-loaded spontaneously hypertensive rats(RARE SUGARS II, Edited by Asada Y, Kawanami Y, Tajima S)2008

Author(s)

Publisher

Data Source

[Journal Article] Cardioprotective effects of a novel calpain inhibitor SNJ-1945 for reperfusion injury after cardioplegic cardiac arrest2010

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of cytochrome c release by 10-N-nonyl acridine orange, a cardiolipin-specific dye, during myocardial ischemia-reperfusion in the rat2010

Author(s)

Journal Title

Data Source

[Journal Article] A 5-HT(4)-receptor activation-induced neural plasticity enhances in vivo reconstructs of enteric nerve circuit insult2010

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of cytochrome c release by 10-N-nonyl acridine orange, acardiolipin-specific dye, during myocardial ischemia-reperfusion in the rat.2010

Author(s)

Journal Title

Data Source

[Journal Article] Role of euronal NO synthase in regulating vascular superoxide levels and mitogen-activated protein kinase phosphorylation2009

Author(s)

Journal Title

Data Source

[Journal Article] Role of neuronal NO synthase in regulating vascular superoxide levels and mitogen-activated protein kinase phosphorylatlon.2009

Author(s)

Journal Title

Data Source

[Journal Article] Left ventricular function of isoproterenol-induced hypertrophied rat hearts perfused with blood: mechanical work and energetics2009

Author(s)

Journal Title

Data Source

[Journal Article] Role of neuronal NO synthase in regulating vascular superoxide levels and mitogen-activated protein kinase phosphorylation2009

Author(s)

Journal Title

Data Source

[Journal Article] Role of neuronal NO synthase in regulating vascular superoxide levels and mitogen-activated protein kinase phos2009

Author(s)

Journal Title

Data Source

[Journal Article] The opposite roles of nNOS in cardiac ischemia-reperfusion-induced injury and in ischemia preconditioning-induced cardioprotection in mice.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Possible involvement of Rho-kinase in aldosterone-induced vascular smooth muscle cell remodeling2008

Author(s)

Journal Title

Data Source

[Journal Article] Aldosterone induces myofibroblastic transdifferentiation and collagen gene expression through the Rho-kinase dependent signaling pathway in rat mesangial cells2008

Author(s)

Journal Title

Data Source

[Journal Article] Aldosterone induces myofibroblastic transdifferentiation and collagen gene expression through the Rho-kinase dependent signaling pathway in rat mesangial cells2008

Author(s)

Journal Title

Data Source

ZHANG Guo-Xing 張国興

ZHANG Guo-xing 張國興