HARIMAYA Atsushi 播摩谷敦

Researcher Number	90448605
Affiliation (based on the past Project Information) *help	2012: 東海大学, 医学部, 講師 2010: Tokai University, 医学部, 講師 2007 – 2009: Sapporo Medical University, 医学部, 助教
Review Section/Research Field	Principal Investigator Otorhinolaryngology
Keywords	Principal Investigator 中耳炎 / アロイオコッカス / 感染免疫 / 耳科学 / ワクチン / シグナル伝達 / alloiococcus otitidis / アロイオコツカス

新種細菌アロイオコッカスに関する基礎的・臨床的研究ならびに臨床診療への応用Principal Investigator
- Principal Investigator
  
  播摩谷敦
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Tokai University
Clinical studies, immunological analysis, and antigen structure analysis about Alloiococcus otitidisPrincipal Investigator
- Principal Investigator
  
  HARIMAYA Atsushi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Tokai University
  Sapporo Medical University
Analysis of the bacterial characters and the pathogenesis of Alloiococcus otitidisPrincipal Investigator
- Principal Investigator
  
  HARIMAYA Atsushi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Sapporo Medical University

All 2010 2009 2008 2007 Other

All Journal Article Presentation Patent

[Journal Article] Thymic stromal lymphopoietin enhances tight-junction barrier function of human nasal epithelial cells.2009
- Author(s)
  Kamekura R, Kojima T, Koizumi JI, Ogasawara N, Kurose M, Go M, Harimaya A, Murata M, Tanaka S, Chiba H, Himi T, Sawada N.
- Journal Title
  
  Cell Tissue Res 338
  
  Pages: 283-293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791627
[Journal Article] Preliminary study of proinflammatory cytokines and chemokines in the middle ear of acute otitis media due to Alloiococcus otitidis.2009
- Author(s)
  Harimaya A, Fujii N, Himi T.
- Journal Title
  
  Int J Pediatr Otorhinolaryngol 73
  
  Pages: 677-680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791627
[Journal Article] Preliminary study of proinflammatory cytokines and chemokines in the middle ear of acute otitis media due to Alloiococcus otitidis.2009
- Author(s)
  Harimaya, et al.
- Journal Title
  
  Int J Pediatr Otorhinolaryngol 73
  
  Pages: 677-680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791627
[Journal Article] 新種細菌アロイオコッカス(Alloiococcus otitidis)の中耳炎における関与について2008
- Author(s)
  播摩谷敦
- Journal Title
  
  北耳報 118
  
  Pages: 1-7
- Data Source
  KAKENHI-PROJECT-19791219
[Journal Article] 新種細菌アロイオコッカス(Alloiococcus otitidis)の中耳炎における関与について。2008
- Author(s)
  播摩谷敦
- Journal Title
  
  北耳報 118
  
  Pages: 1-7
- Data Source
  KAKENHI-PROJECT-19791219
[Journal Article] 髄膜炎を発症した内耳奇形の成人症例。2008
- Author(s)
  播摩谷敦,氷見徹夫
- Journal Title
  
  日本耳鼻咽喉科感染症研究会会誌 26
  
  Pages: 173-176
- Data Source
  KAKENHI-PROJECT-19791219
[Journal Article] PKC enhances tight junction barrier function of human nasal epithelial cells in primary culture by transcriptional regulation.2008
- Author(s)
  Koizumi JI, Kojima T, Ogasawara N, Kamekura R, Kurose M, Go M, Harimaya A, Murata M, Osanai M, Chiba H, Himi T, Sawada N.
- Journal Title
  
  Mol Pharmacol 74
  
  Pages: 432-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791219
[Journal Article] 髄膜炎を発症した内耳奇形の成人症例2008
- Author(s)
  播摩谷敦ら
- Journal Title
  
  日本耳鼻咽喉科感染症研究会会誌 26
  
  Pages: 173-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791219
[Journal Article] Remarkably high prevalence of ftsl gene mutations in Haemophilus inflienzae isolates from the upper respiratory tract infections in children of the Sapporo district, Japan2008
- Author(s)
  Harimaya A, et.al.
- Journal Title
  
  J Infect Chemother 14
  
  Pages: 223-227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791219
[Journal Article] Remarkably high prevalence of fts1 gene mutations in Haemophilus influenzae isolates from the upper respiratory tract infections in children of the Sapporo district, Japan.2008
- Author(s)
  Harimaya A, Yokota S, Sato K, Himi T, Fujii N.
- Journal Title
  
  J Infect Chemother 14
  
  Pages: 223-227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791219
[Journal Article] Evidence of local antibody response against Alloiococcus otitidis in the middle ear cavity of children with otitis media2007
- Author(s)
  Harimaya A.
- Journal Title
  
  FEMS Immounol MedMicrobiol 49
  
  Pages: 4145-4145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791219
[Journal Article] Changes of gap and tight junctions during differentiation of human nasal epithelial cells using primary human nasal epithelial cells and primary human nasal fibroblast cells in a non-contact co-culture system.2007
- Author(s)
  Koizumi J, Kojima T, Kamekura R, Kurose M, Harimaya A, Murata M, Osanai M, Chiba H, Himi T, Sawada N.
- Journal Title
  
  J Membr Biol 218
  
  Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791219
[Journal Article] High prevalence of erythromycin resistance and macrolide-resistance genes,mefA and ermB,in Streptococcus pneumoniae isolates2007
- Author(s)
  Harimaya A.
- Journal Title
  
  J Infect Chemother 13
  
  Pages: 219-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791219
[Journal Article] Interleukin-8 induction via NF-kappaB,p38 mitogen-activated protein kinase and extracellular signal-regulated kinase1/2 pathways2007
- Author(s)
  Harimaya A.
- Journal Title
  
  Int J Pediatr Otorhinolaryngol 71
  
  Pages: 1465-1470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791219
[Journal Article] High prevalence of erythromycin resistance and macrolide-resistance genes, mefA and ermB, in Streptococcus pneumoniae isolates from the upper respiratory tract of children in Sapporo district, Japan.2007
- Author(s)
  Harimaya A, Yokota S, Sato K, Yamazaki N, Himi T, Fujii N.
- Journal Title
  
  J Infect Chemother 13
  
  Pages: 219-223
- NAID
  10019547949
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791219
[Journal Article] Evidence of local antibody response against Alloiococcus otitidis in the middle ear cavity of children with otitis media.2007
- Author(s)
  Harimaya A, Takada R, Himi T, Yokota S, Fujii N.
- Journal Title
  
  FEMS Immunol Med Microbiol 49
  
  Pages: 41-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791219
[Journal Article] Interleuki-8 induction via NF-kappaB, p38 mitogen-activated protein kinase and extracellular signal-regulated kinase 1/2 pathways in human peripheral blood mononuclear cells by Alloiococcus otitidis.2007
- Author(s)
  Harimaya A, Koizumi J, Fujii N, Himi T.
- Journal Title
  
  Int J Pediatr Otorhinolaryngol 71
  
  Pages: 1465-1470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791219
[Journal Article] Impact of anaerobic and oligotrophic conditions on survival of Alloiococcus otitidis, implicated as a cause of otitis media.
- Author(s)
  Matsuo,Harimaya, et al.
- Journal Title
  
  J Infect Chemother
  
  Volume: (in press)
- NAID
  10029523562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791627
[Journal Article] Impact of anaerobic and oligotrophic conditions on survival of Alloiococcus otitidis, implicated as a cause of otitis media.
- Author(s)
  Matsuo J, Harimaya A, Fukumoto T, Nakamura S, Yoshida M, Takahashi K, Iida M, Fujii N, Yamaguchi H.
- Journal Title
  
  J Infect Chemother 印刷中
- NAID
  10029523562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791627
[Patent] Novel polysaccharide immunogens from Alloiococcus otitidis and synthesis of a glycoconjugate vaccine thereof.2009
- Inventor(s)
  Montero MA, Arar S, Harimaya A
- Industrial Property Rights Holder
  Montero MA, Arar S, Harimaya A
- Acquisition Date
  2009-03-19
- Overseas
- Data Source
  KAKENHI-PROJECT-21791627
[Patent] Novel polysaccharide immunogens from Alloiococcus otitidis and synthesis of a glycoconjugate vaccine thereof.2008
- Inventor(s)
  Monteiro MA, Arar S, Harimaya A
- Industrial Property Rights Holder
  Monteiro MA, Arar S, Harimaya A
- Filing Date
  2008-12-07
- Overseas
- Data Source
  KAKENHI-PROJECT-19791219
[Presentation] 小児中耳炎の新たな原因菌と考えられるAlloiococcus otitidisの生存性を規定する要因に関する基礎的な検討2010
- Author(s)
  福元達也、播摩谷敦、松尾淳司、秋沢宏次、清水力、飯田政弘、藤井暢弘、山口博之
- Organizer
  第84回日本感染症学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21791627
[Presentation] 新種細菌アロイオコッカスの中耳炎における臨床的意義について2010
- Author(s)
  播摩谷敦
- Organizer
  第73回相武耳鼻科研究会
- Place of Presentation
  厚木市
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-21791627
[Presentation] 中耳炎好発児におけるアデノイド手術前後の鼻咽腔細菌叢動態に関する検討2010
- Author(s)
  播摩谷敦、新谷朋子、氷見徹夫、濱田昌史、小田桐恭子、関口美也子、塚原桃子、飯田政弘
- Organizer
  第20回日本耳科学会総会・学術講演会
- Place of Presentation
  松山市
- Data Source
  KAKENHI-PROJECT-21791627
[Presentation] Alloiococcus otitidis induces interleukin-8 via NF-kappaB, p38 mitogen-activated protein kinase and extracellular signal-regulated kinase 1/2 pathways in human cells.2010
- Author(s)
  Harimaya A, Fujii N, Himi T, Iida M.
- Organizer
  13th Korea-Japan Joint Meeting of Otorhinolaryngology=Head and Neck Surgery.
- Place of Presentation
  Seoul, Korea.
- Data Source
  KAKENHI-PROJECT-21791627
[Presentation] 新種中耳起炎菌アロイオコッカスの至適発育条件に関する検討2010
- Author(s)
  播摩谷敦
- Organizer
  感染症治療フォーラム
- Place of Presentation
  伊勢原市
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21791627
[Presentation] 反復性中耳炎小児におけるアデノイド切除前後の鼻咽腔細菌叢の動態について2010
- Author(s)
  播摩谷敦、新谷朋子、濱田昌史、小田桐恭子、関口美也子、塚原桃子、飯田政弘
- Organizer
  日本耳鼻咽喉科学会神奈川県地方部会
- Place of Presentation
  横浜
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-21791627
[Presentation] 小児中耳炎の新種細菌に関する話題について2010
- Author(s)
  播摩谷敦
- Organizer
  川崎市耳鼻咽喉科医会
- Place of Presentation
  川崎市
- Year and Date
  2010-12-18
- Data Source
  KAKENHI-PROJECT-21791627
[Presentation] Alloiococcus otitidis induoes interleukin-8 via NF-kappaB, p38 mitogen-activated protein kinase and extracellular signal-regulated kinase1/2 pathways in human cells.2010
- Author(s)
  Harimaya, et al.
- Organizer
  13th Korea-Japan Joint Meeting of Otorhinolaryngology-Head and Neck Surgery
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-21791627
[Presentation] 小児中耳炎の新たな原因菌と考えられるAlloiococcus otitidisの生存性2010
- Author(s)
  福元達也、播摩谷敦、松尾淳司、鈴木春樹、清水力、松野一彦、飯田政弘、藤井暢弘、山口博之
- Organizer
  第57回日本臨床検査医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21791627
[Presentation] 新種細菌Alloiococcus otitidis菌体成分に対する抗体の検出、ならびに多糖体抗原の構造解析2009
- Author(s)
  播摩谷敦、Mario A Monteiro、横田伸一、氷見徹夫、藤井暢弘
- Organizer
  第110回日本耳鼻咽喉科学会総会・学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21791627
[Presentation] 新種細菌アロイオコッカスの中耳炎における臨床的意義について2009
- Author(s)
  播摩谷敦
- Organizer
  URIEM
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21791627
[Presentation] 新種細菌Alloiococcus otitidis菌体成分に対する抗体の検出、ならびに多糖体抗原の構造解析。2009
- Author(s)
  播摩谷敦, ら
- Organizer
  第110回日本耳鼻咽喉科学会総会・学術講演会
- Place of Presentation
  東京
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-21791627
[Presentation] 新種細菌Alloiococcus otitidis菌体成分に対する抗体の検出、ならびに多糖体抗原の構造解析2008
- Author(s)
  播摩谷敦ら
- Organizer
  第18回日本耳科学会総会・学術講演会
- Place of Presentation
  神戸
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-19791219
[Presentation] 中耳炎好発児における鼻咽腔細菌叢の動態について2008
- Author(s)
  播摩谷敦
- Organizer
  第5回札幌耳鼻咽喉科感染症フォーラム
- Place of Presentation
  札幌
- Year and Date
  2008-03-15
- Data Source
  KAKENHI-PROJECT-19791219
[Presentation] 新種細菌Alloiococcus otitidis菌体成分に対する抗体の検出、ならびに多糖体抗原の構造解析。2008
- Author(s)
  播摩谷敦、Mario A Monteiro、氷見徹夫、藤井暢弘
- Organizer
  第18回日本耳科学会総会・学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19791219
[Presentation] 小児鼻咽腔細菌叢における中耳炎起炎菌のアデノイド切除術前後の動態2007
- Author(s)
  播摩谷敦
- Organizer
  日本耳科学会総会
- Place of Presentation
  福岡
- Year and Date
  2007-10-18
- Data Source
  KAKENHI-PROJECT-19791219
[Presentation] アデノイド切除術前後における小児鼻咽腔細菌叢の動態に関する検討2007
- Author(s)
  小笠原徳子、播摩谷敦、新谷朋子、氷見徹夫
- Organizer
  日本小児耳鼻咽喉科学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19791219
[Presentation] 小児鼻咽腔細菌叢における中耳炎起炎菌のアデノイド切除術前後の動態2007
- Author(s)
  小笠原徳子、播摩谷敦、新谷朋子、氷見徹夫
- Organizer
  第17回日本耳科学会総会学術講演会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19791219
[Presentation] 髄膜炎を発症した内耳奇形の2成人例2007
- Author(s)
  播摩谷敦、三上毅、宝金清博、氷見徹夫
- Organizer
  第37回日本耳鼻咽喉科感染症研究会
- Place of Presentation
  旭川
- Data Source
  KAKENHI-PROJECT-19791219
[Presentation] 耳鼻咽喉科領域感染症と抗菌剤2007
- Author(s)
  播摩谷敦
- Organizer
  アステラス製薬社内勉強会
- Place of Presentation
  札幌
- Year and Date
  2007-11-13
- Data Source
  KAKENHI-PROJECT-19791219
[Presentation] テロメラーゼ遺伝子導入培養ヒト鼻粘膜上皮細胞におけるTGF-βによるclaudin-4の発現誘導2007
- Author(s)
  黒瀬誠、小泉純一、亀倉隆太、高野賢一、郷充、播摩谷敦、氷見徹夫
- Organizer
  第108回日本耳鼻咽喉科学会総会・学術講演会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-19791219

1. FUJII Nobuhiro

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
2. YOKOTA Shin-ichi

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. HIMI Tetsuo

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
4. YAMAGUTI Hiroyuki

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. MONTEIRO Mario A.

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. ALAR Sharif

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. SOMEKAWA Yukihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IIDA Masahiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. YLIKOSKI Jukka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MATTILA Petri

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TARKKANEN Jussi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HARIMAYA Atsushi 播摩谷 敦

Research Projects

Research Products

Co-Researchers

新種細菌アロイオコッカスに関する基礎的・臨床的研究ならびに臨床診療への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinical studies, immunological analysis, and antigen structure analysis about Alloiococcus otitidisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the bacterial characters and the pathogenesis of Alloiococcus otitidisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Thymic stromal lymphopoietin enhances tight-junction barrier function of human nasal epithelial cells.2009

Author(s)

Journal Title

Data Source

[Journal Article] Preliminary study of proinflammatory cytokines and chemokines in the middle ear of acute otitis media due to Alloiococcus otitidis.2009

Author(s)

Journal Title

Data Source

[Journal Article] Preliminary study of proinflammatory cytokines and chemokines in the middle ear of acute otitis media due to Alloiococcus otitidis.2009

Author(s)

Journal Title

Data Source

[Journal Article] 新種細菌アロイオコッカス(Alloiococcus otitidis)の中耳炎における関与について2008

Author(s)

Journal Title

Data Source

[Journal Article] 新種細菌アロイオコッカス(Alloiococcus otitidis)の中耳炎における関与について。2008

Author(s)

Journal Title

Data Source

[Journal Article] 髄膜炎を発症した内耳奇形の成人症例。2008

Author(s)

Journal Title

Data Source

[Journal Article] PKC enhances tight junction barrier function of human nasal epithelial cells in primary culture by transcriptional regulation.2008

Author(s)

Journal Title

Data Source

[Journal Article] 髄膜炎を発症した内耳奇形の成人症例2008

Author(s)

Journal Title

Data Source

[Journal Article] Remarkably high prevalence of ftsl gene mutations in Haemophilus inflienzae isolates from the upper respiratory tract infections in children of the Sapporo district, Japan2008

Author(s)

Journal Title

Data Source

[Journal Article] Remarkably high prevalence of fts1 gene mutations in Haemophilus influenzae isolates from the upper respiratory tract infections in children of the Sapporo district, Japan.2008

Author(s)

Journal Title

Data Source

[Journal Article] Evidence of local antibody response against Alloiococcus otitidis in the middle ear cavity of children with otitis media2007

Author(s)

Journal Title

Data Source

[Journal Article] Changes of gap and tight junctions during differentiation of human nasal epithelial cells using primary human nasal epithelial cells and primary human nasal fibroblast cells in a non-contact co-culture system.2007

Author(s)

Journal Title

Data Source

[Journal Article] High prevalence of erythromycin resistance and macrolide-resistance genes,mefA and ermB,in Streptococcus pneumoniae isolates2007

Author(s)

Journal Title

Data Source

[Journal Article] Interleukin-8 induction via NF-kappaB,p38 mitogen-activated protein kinase and extracellular signal-regulated kinase1/2 pathways2007

Author(s)

Journal Title

Data Source

[Journal Article] High prevalence of erythromycin resistance and macrolide-resistance genes, mefA and ermB, in Streptococcus pneumoniae isolates from the upper respiratory tract of children in Sapporo district, Japan.2007

Author(s)

HARIMAYA Atsushi 播摩谷敦