HIROKAWA Go 廣川剛

Researcher Number	90450890
Affiliation (based on the past Project Information) *help	2013: 独立行政法人国立循環器病研究センター, 研究所, 室長 2010: 独立行政法人国立循環器病研究センター, 病態ゲノム医学部, 室長 2009: National Cardiovascular Center Research Institute, 疫学部, 室長 2008: National Cardiovascular Center Research Institute, 疫学部, 室長 2008: National Cardiovascular Center Research Institute, 疫学部, 室長 2007: National Cardiovascular Center Research Institute, 研究所・疫学部, 室長
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Biological pharmacy Except Principal Investigator Cerebral neurosurgery
Keywords	Principal Investigator 血漿RNA / マイクロRNA / バイオマーカー / 虚血性心疾患 / 蛋白質生合成 Except Principal Investigator ケース・コントロール研究 / esRAGE / sRAGE / バイオマーカー / カットオフ値 … More / 急性期脳卒中 / 急性脳卒中 / 吹田コホート / LOX-1 / ペントシジン / 終末糖化産物受容体関連物質 Less

Clinical implication of biomarker for patients with acute stroke
- Principal Investigator
  
  YOKOTA Chiaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  National Cardiovascular Center Research Institute
血漿microRNAは循環器疾患マーカーとして有用か?Principal Investigator
- Principal Investigator
  
  廣川剛
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National Cardiovascular Center Research Institute
Mechanism of ribosome splittingPrincipal Investigator
- Principal Investigator
  
  HIROKAWA Go
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Cardiovascular Center Research Institute

All 2009 2008 2007

All Journal Article Presentation

[Journal Article] Insights into ribosome recycling factor interactions with the 70S ribosome.2008
- Author(s)
  Pai RD, Zhang W, Schuwirth BS, Hirokawa G, Kaji H, Kaji A, Cate JH., Structural
- Journal Title
  
  J Mol Biol 376
  
  Pages: 1334-1347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790088
[Journal Article] Targeted deletion of miR-182, an abundant retinal microRNA.2008
- Author(s)
  Jin ZB, Hirokawa G, Gui L, Takahashi R, Osakada F, Hiura Y, Takahashi M, Yasuhara O, Iwai N
- Journal Title
  
  Mol. Vis 15
  
  Pages: 523-533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790088
[Journal Article] The role of GTP in transient splitting of 70S ribosomes by RRF (ribosome recycling factor) and EF-G (elongation factor G)2008
- Author(s)
  Hirokawa G., et al.
- Journal Title
  
  Nucleic Acids Res. 36
  
  Pages: 6676-6687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790088
[Journal Article] The role of GTP in transient splitting of 70S ribosomes by RRF (ribosome recycling factor) and EF-G (elongation factor G).2008
- Author(s)
  Hirokawa G, Iwakura N, Kaji A, Kaji H
- Journal Title
  
  Nucleic Acids Res 36
  
  Pages: 6676-6687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790088
[Journal Article] Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.2007
- Author(s)
  Borovinskaya MA, Pai RD, Zhang W, Schuwirth BS, Holton JM, Hirokawa G, Kaji H, Kaji A, Cate JH
- Journal Title
  
  Nature Struct Mol Biol 14
  
  Pages: 727-732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790088
[Journal Article] Novel activity of eukaryotic trasnlocase, eEF2 : dissociation of the 80S ribosome into subunits with ATP but not with GTP.2007
- Author(s)
  Demeshkina N, Hirokawa G, Kaji A, Kaji H
- Journal Title
  
  Nucleic Acids Res 35
  
  Pages: 4597-4607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790088
[Journal Article] Minor contribution of an internal ribosome entry site in the 5'-UTR of ornithine decarboxylase mRNA on its translation.2007
- Author(s)
  Nishimura K, Sakuma A, Yamashita T, Hirokawa G, Imataka H, Kashiwagi K, Igarashi K
- Journal Title
  
  Biochem Biophys Res Commun 364
  
  Pages: 124-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790088
[Presentation] 腎障害の指標としての尿中マイクロRNAの意義2009
- Author(s)
  廣川剛
- Organizer
  第32回日本高血圧学会
- Place of Presentation
  大津プリンスホテル
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21659205
[Presentation] Serum microRNAs are promising biomarkers for several caridiovascular diseases2009
- Author(s)
  Ji X, Takahashi R, Hirokawa G, Hiura Y, Iwai N
- Organizer
  第73回日本循環器学会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-19790088
[Presentation] Plasma Levels of miR-208 as a Biomarker of Myocardial Injury2009
- Author(s)
  廣川剛
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21659205
[Presentation] Validation of computer predicted target genes of mammalian microRNA-1822008
- Author(s)
  Le Gui, 廣川剛, 福島康江, 岩井直温
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-19790088
[Presentation] Is the expression profile of mRNA correlated with that of miRNA during adipocyte differentication ?2007
- Author(s)
  Le Gui, 廣川剛, 岩井直温
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19790088

1. 岩井直温 (30242978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. YOKOTA Chiaki (80300979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KOKUBO Yoshihiro (20393217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SAWAMURA Tatsuya (30243033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NISHIMURA Kunihiro (70397834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HIROKAWA Go 廣川 剛

Research Projects

Research Products

Co-Researchers

Clinical implication of biomarker for patients with acute stroke

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

血漿microRNAは循環器疾患マーカーとして有用か?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of ribosome splittingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Insights into ribosome recycling factor interactions with the 70S ribosome.2008

Author(s)

Journal Title

Data Source

[Journal Article] Targeted deletion of miR-182, an abundant retinal microRNA.2008

Author(s)

Journal Title

Data Source

[Journal Article] The role of GTP in transient splitting of 70S ribosomes by RRF (ribosome recycling factor) and EF-G (elongation factor G)2008

Author(s)

Journal Title

Data Source

[Journal Article] The role of GTP in transient splitting of 70S ribosomes by RRF (ribosome recycling factor) and EF-G (elongation factor G).2008

Author(s)

Journal Title

Data Source

[Journal Article] Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.2007

Author(s)

Journal Title

Data Source

[Journal Article] Novel activity of eukaryotic trasnlocase, eEF2 : dissociation of the 80S ribosome into subunits with ATP but not with GTP.2007

Author(s)

Journal Title

Data Source

[Journal Article] Minor contribution of an internal ribosome entry site in the 5'-UTR of ornithine decarboxylase mRNA on its translation.2007

Author(s)

Journal Title

Data Source

[Presentation] 腎障害の指標としての尿中マイクロRNAの意義2009

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Serum microRNAs are promising biomarkers for several caridiovascular diseases2009

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Plasma Levels of miR-208 as a Biomarker of Myocardial Injury2009

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Validation of computer predicted target genes of mammalian microRNA-1822008

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Is the expression profile of mRNA correlated with that of miRNA during adipocyte differentication ?2007

Author(s)

Organizer

Place of Presentation

Data Source

HIROKAWA Go 廣川剛