SATOSHI Somekawa 染川智

Researcher Number	90453167
Affiliation (based on the past Project Information) *help	2013: 奈良県立医科大学, 医学部, 助教 2013: 奈良県立医科大学, 医学部, 講師 2010 – 2011: 奈良県立医科大学, 医学部, 講師 2009: Nara Medical University, 医学部・附属病院, 研究員 2008 – 2009: Nara Medical University, 医学部, 助教
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Cardiovascular medicine Except Principal Investigator Cardiovascular medicine
Keywords	Principal Investigator アルドステロン / 血管新生 / 食塩 / ナトリウム利尿ペプチド / グアニリルシクラーゼ / 転写抑制因子NRSF / 心不全 / 副腎 / NRSE / NRSF … More Except Principal Investigator … More BMP9 / 血管新生 / ALK1 / ＧＰＲ78 / IP3受容体 / BMP9/10 / 右心不全 / 肺高血圧 / TMEM100 Less

A Nobel Protein TMEM100 and Pulmonary Hypertension and Right-sided Heart Failure.
- Principal Investigator
  
  SAITO YOSHIHIKO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Nara Medical University
動脈分化および成体血管新生におけるTMEM100分子の機能的意義の解明Principal Investigator
- Principal Investigator
  
  染川智
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Nara Medical University
The role of GC-A signaling against aldosterone and salt-induced cardiac remodelingPrincipal Investigator
- Principal Investigator
  
  SOMEKAWA Satoshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Nara Medical University
The Role of NRSF in Heart Failure (Cardio-Adrenal Connection)Principal Investigator
- Principal Investigator
  
  SATOSHI Somekawa
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Nara Medical University

All 2015 2014 2013 2010 2009 2008

All Journal Article Presentation

[Journal Article] Evaluation of coronary artery disease and cardiac morphology and function in patients with hypertrophic cardiomyopathy, using cardiac computed tomography.2015
- Author(s)
  Okayama S, Soeda T, Kawakami R, Takami Y, Somekawa S, Ueda T, Sugawara Y, Matsumoto T, Sung JH, Nishida T, Uemura S, Saito Y.
- Journal Title
  
  Heart Vessels.
  
  Volume: 30 Issue: 1 Pages: 28-35
- DOI
  10.1007/s00380-013-0452-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293187
[Journal Article] Impairment of endothelial-mesenchymal transformation during atrioventriucular cushion formation in Tmem100 null embryo2015
- Author(s)
  Mizuta K., Sakabe M., Ioka T., Hashimoto A., Ioka T., Sakai C., Okumura K., Hattammaru M., Fujita M., Araki M., Somekawa S., Saito Y., Nakagawa O
- Journal Title
  
  Developmental Dynamics
  
  Volume: 244 Issue: 1 Pages: 31-42
- DOI
  10.1002/dvdy.24216
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25111728, KAKENHI-PROJECT-25670492, KAKENHI-PROJECT-25293187
[Journal Article] Suppressed soluble Fms-like tyrosine kinase-1 production aggravates atherosclerosis in chronic kidney disease2014
- Author(s)
  Matsui M, Takeda Y, Uemura S, Matsumoto T, Seno A, Onoue K, Tsushima H, Morimoto K, Soeda T, Okayama S, Somekawa S, Samejima K, Kawata H, Kawakami R, Nakatani K, Iwano M, Saito Y.
- Journal Title
  
  Kidney Int
  
  Volume: 85(2) Issue: 2 Pages: 393-403
- DOI
  10.1038/ki.2013.339
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24659415, KAKENHI-PROJECT-25293187, KAKENHI-PROJECT-25461226
[Journal Article] Suppressed Soluble Fms-Like Tyrosine Kinase-1 Production Aggravates Atherosclerosis in CKD : Evaluation by Circulating sFlt-1 Levels after Low-Dose Heparin Injection.2014
- Author(s)
  Matsui M, Takeda Y, Uemura S, Matsumoto T, Seno A, Onoue K, Tsushima H, Morimoto K, Soeda T, Okayama S, Somekawa S, Samejima K, Kawata H, Kawakami R, Nakatani K, Iwano M, Saito Y.
- Journal Title
  
  Kid Int.
  
  Volume: 85 Pages: 393-403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293187
[Journal Article] Noncardiovascular death, especially infection, is a significant cause of death in elderly patients with acutely decompensated heart failure.2014
- Author(s)
  Ueda T, Kawakami R, Horii M, Sugawara Y, Matsumoto T, Okada S, Nishida T, Soeda T, Okayama S, Somekawa S, Takeda Y, Watanabe M, Kawata H, Uemura S, Saito Y.
- Journal Title
  
  J Card Fail.20:174-80, 2014
  
  Volume: 20 Issue: 3 Pages: 174-180
- DOI
  10.1016/j.cardfail.2013.12.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293187
[Journal Article] Nuclear accumulation of androgen receptor in gender difference of dilated cardiomyopathy due to lamin A/C mutations.2013
- Author(s)
  Arimura T, Onoue K, Takahashi-Tanaka Y, Ishikawa T, Kuwahara M, Setou M, Shigenobu S, Yamaguchi K, Bertrand AT, Machida N, Takayama K, Fukusato M, Tanaka R, Somekawa S, Nakano T, Yamane Y, Kuba K, Imai Y, Saito Y, Bonne G, Kimura A.
- Journal Title
  
  Cardiovasc Res.
  
  Volume: 99 Pages: 382-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293187
[Journal Article] High mean corpuscular volume (MCV) is a new predictor of prognosis in patients with acute decompensated heart failure.2013
- Author(s)
  Ueda T, Kawakami R, Horii M, Sugawara Y, Matsumoto T, Okada S, Nishida T, Soeda T, Okayama S, Somekawa S, Takeda Y, Watanabe M, Kawata H, Uemura S, Saito Y.
- Journal Title
  
  Circ J.
  
  Volume: 77 Pages: 2766-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293187
[Journal Article] アルドステロン拮抗薬2010
- Author(s)
  染川智、上村史朗、斎藤能彦
- Journal Title
  
  綜合臨牀
- Data Source
  KAKENHI-PROJECT-20790543
[Journal Article] アルドステロン拮抗薬2010
- Author(s)
  染川智
- Journal Title
  
  総合臨床
  
  Volume: 59 Pages: 54-59
- Data Source
  KAKENHI-PROJECT-22790721
[Journal Article] Morphological features of coronary arteries in patients with coronary spastic angina: Assessment with intracoronary optical coherence tomography2009
- Author(s)
  Morikawa Y, Uemura S, Ishigami K, Soeda T, Okayama S, Takemoto Y, Onoue K, Somekawa S, Nishida T, Takeda Y, Kawata H, Horii M Saito Y
- Journal Title
  
  Int J Cardiol (in press)
- Data Source
  KAKENHI-PROJECT-20790543
[Journal Article] Regulation of aldosterone and cortisol production by the transcriptional repressor neuron restrictive silencer factor2009
- Author(s)
  Somekawa S, Imagawa K, Naya N, Takemoto Y, Onoue K, Okayama S, Takeda Y, Kawata H, Horii M, Nakajima T, Uemura S Mochizuki N, Saito Y.
- Journal Title
  
  Endocrinology 150(7)
  
  Pages: 3110-3117
- Data Source
  KAKENHI-PROJECT-20790543
[Journal Article] Reduction of circulating soluble fms-like tyrosine kinase-1 plays a significant role in renal dysfunction-associated aggravation of atherosclerosis2009
- Author(s)
  Onoue K, Uemura S, Takeda Y, Somekawa S, Iwama H, Imagawa K, Nishida T, Morikawa Y, Takemoto Y, Asai O, Soeda T, Okayama S, Ishigami K, Nakatani K, Kawata H, Horii M, NakajimaT, Altai Y, Iwano M, Saito Y.
- Journal Title
  
  Circulation 120(24)
  
  Pages: 2470-2477
- Data Source
  KAKENHI-PROJECT-20790543
[Journal Article] Regulation of aldosterone and cortisol production by the transcriptional repressor neuron restrictive silencer factor2009
- Author(s)
  Somekawa S
- Journal Title
  
  Endocrinology 150
  
  Pages: 3110-3117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790543
[Journal Article] Usefulness of soluble Fms-like tyrosine kinase I as a biomarker of acute severe heart failure in patients with acute myocardial infarction2009
- Author(s)
  Onoue K, Uemura S, Takeda Y, Somekawa S, Iwama H, Nishida T, Morikawa Y, Nakagawa H, Tsutsumi, T Sung JH, Takemoto Y, Soeda T, Okayama S, Ishigami K, Kawata H, Horii M, Nakajima T, Saito Y
- Journal Title
  
  Am J Cardiol (in press)
- Data Source
  KAKENHI-PROJECT-20790543
[Journal Article] Novel application of black-blood echo-planar imaging to the assessment of myocardial infarction2009
- Author(s)
  Okayama S, Uemura S, Watanabe M, Morikawa Y, Onoue K, Soeda T, Iwama H, Somekawa S, Takeda Y, Uramoto H, Kobayashi Y, Saito Y
- Journal Title
  
  Heart and Vessel (in press)
- Data Source
  KAKENHI-PROJECT-20790543
[Journal Article] Long term follow-up of neointimal coverage of sirolimus-eluting stouts: Evaluation with optical coherencetomography2009
- Author(s)
  Ishigami K, Uemura S, Morikawa Y, Soeda T, Okayama S, Nishida T, Takemoto Y, Onoue K, Somekawa S, Takeda Y, Kawata H, Horii M Saito Y
- Journal Title
  
  Circ J (in press)
- Data Source
  KAKENHI-PROJECT-20790543
[Journal Article] Treatment with recombinant placental growth factor (PIGF) enhances both angiogensis and arteriogenesis and improves survival after myocardial infarction2009
- Author(s)
  Takeda Y, Uemura S, Iwama H, Imagawa K, Nishida T, Onoue K, Takemoto Y, Soeda T, Okayama S, Somekawa S, Ishigami K, Takaoka M, Kawata H, Kubo A, Horii M, Nakajima T, Saito Y
- Journal Title
  
  Circ. J 73(9)
  
  Pages: 1674-1682
- Data Source
  KAKENHI-PROJECT-20790543
[Journal Article] Human placental ectonucleoside triphosphate diphosphohydrolase gene transfer via gelatin-coated stents prevents in-stent thrombosis2009
- Author(s)
  Takemoto Y, Kawata H, Soeda T, Imagawa K, Somekawa S, Takeda Y, Uemura S, Matsumoto M, Fujimura Y, Jo J, Kimura Y, Tabata Y, Saito Y.
- Journal Title
  
  Arterioscler Thromb Vase Biol. 29(6)
  
  Pages: 857-862
- Data Source
  KAKENHI-PROJECT-20790543
[Journal Article] Non-contrast MRI for the evaluation of hydronephrotic and dysfunctioning kidney secondary to testicular cancer2009
- Author(s)
  Okayama 5, Matsui M, Somekawa S, Iwano M, Saito Y.
- Journal Title
  
  lien Fail 31(2)
  
  Pages: 153-158
- Data Source
  KAKENHI-PROJECT-20790543
[Journal Article] Progression of non-culprit coronary artery atherosclerosis after acute myocardial infarction in comparison with stable angina pectoris2008
- Author(s)
  Okayama S, Uemura S, Nishida T, Morikawa Y, Onoue K, Takemoto Y, Soeda T, Somekawa S, Ishigami K, Takeda Y, Horii M, Kawata H, Takaoka M, Nakajima T, Saito Y.
- Journal Title
  
  J. Atheroscler. Thromb 15(5)
  
  Pages: 228-234
- Data Source
  KAKENHI-PROJECT-20790543
[Journal Article] The specific mineralocorticoid receptor blocker eplerenone attenuates left ventricular remodeling in mice lacking the gene encoding guanylyl cyclase-A2008
- Author(s)
  Zhang Q, Saito Y, Naya N, Imagawa K, Somekawa S, Kawata H, Takeda Y, Uemura S, Kishimoto I, Nakao K.
- Journal Title
  
  Hypertens. Res. 31(6)
  
  Pages: 1251-1256
- Data Source
  KAKENHI-PROJECT-20790543
[Journal Article] The Specific Mineralocorticoid Receptor Blocker Eplerenone Attenuates Left Ventricular Remodeling in Mice Lacking the Gene Encoding Guanylyl Cyclase-A2008
- Author(s)
  Q Zhang, Saito Y, Naya N, Imagawa K, Somekawa S, Kawata H, Takeda Y, Uemura S, et.al.
- Journal Title
  
  Hypertension Research 31
  
  Pages: 1251-1256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790543
[Presentation] Worsening of Renal Function after One Year, Not During Hospitalization, is Stronger Predictor of Prognosis in Patients With ADHF.2013
- Author(s)
  Ueda T, Kawakami R, Sugawara Y, Matsumoto T, Okada S, Soeda T, Okayama S, Somekawa, Takeda Y, Watanabe M, Kawata H, Uemura S, Saito Y.
- Organizer
  American Heart Association
- Place of Presentation
  Dallas, Texas, USA
- Data Source
  KAKENHI-PROJECT-25293187
[Presentation] Uremic Toxin Aggravates Atherosclerosis by Suppression of Endothelial Soluble Flt-1 Production in CKD.2013
- Author(s)
  akeda Y, Uemura S, Matsui M, Matsumoto T, Seno A, Okada S, Nishida T, Soeda T, Okayama S, Somekawa S, Watanabe M, Kawata H, Kawakami R, Saito Y.
- Organizer
  American Heart Association
- Place of Presentation
  Dallas, Texas, USA
- Data Source
  KAKENHI-PROJECT-25293187
[Presentation] GC-A Signaling Attenuates Salt Toxicity on Aldosterone-Induced Cardiac Remodeling2010
- Author(s)
  Somekawa S.
- Organizer
  Cardiovascular Endocrinology and Metabolism (CVEM)
- Place of Presentation
  Nara
- Year and Date
  2010-04-01
- Data Source
  KAKENHI-PROJECT-22790721
[Presentation] GC-A Signaling Attenuates Salt Toxicity on Aldosterone-Induced Cardiac Remodeling2010
- Author(s)
  Somekawa S, Hitoshi N, Matsumoto T, Sung J H, Nishida T, Soeda T, Takemoto Y, Onoue K, Okayama S, Ishigami K, Takeda Y, Kawata H, Horii M, Uemura S, Saito Y
- Organizer
  International Symposium on Cardiovascular Endocrinology and Metabolism(CVEM)
- Place of Presentation
  Nara, Japan
- Data Source
  KAKENHI-PROJECT-22790721
[Presentation] Guanylyl Cyclase-A Signaling Attenuates Salt Effect on Aldosterone -Induced Cardiac Remodeling2009
- Author(s)
  Somekawa S, Oingfen Mang. Nakagawa H, Sung J, Nishida T, Soeda T, Takemoto Y, Onoue K. Okayama S, Ishigami K, Kawata H, Horii M, Uemura S, Saito Y
- Organizer
  American Heart Association Scientific Session
- Data Source
  KAKENHI-PROJECT-20790543
[Presentation] Guanylyl Cyclase-A Signaling Attenuates Salt Effect on Aldosterone -Induced Cardiac Remodeling2009
- Author(s)
  Somekawa S
- Organizer
  Ainerican Heart Association Scientific Session 2009
- Place of Presentation
  オーランド(米国)
- Year and Date
  2009-11-18
- Data Source
  KAKENHI-PROJECT-20790543

1. SAITO YOSHIHIKO (30250260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. ONOUE Kenji (90510173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. IWANO Masayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. SAKABE Masahide

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 斉藤能彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results

SATOSHI Somekawa 染川 智

Research Projects

Research Products

Co-Researchers

A Nobel Protein TMEM100 and Pulmonary Hypertension and Right-sided Heart Failure.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

動脈分化および成体血管新生におけるTMEM100分子の機能的意義の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of GC-A signaling against aldosterone and salt-induced cardiac remodelingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Role of NRSF in Heart Failure (Cardio-Adrenal Connection)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Evaluation of coronary artery disease and cardiac morphology and function in patients with hypertrophic cardiomyopathy, using cardiac computed tomography.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impairment of endothelial-mesenchymal transformation during atrioventriucular cushion formation in Tmem100 null embryo2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Suppressed soluble Fms-like tyrosine kinase-1 production aggravates atherosclerosis in chronic kidney disease2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Suppressed Soluble Fms-Like Tyrosine Kinase-1 Production Aggravates Atherosclerosis in CKD : Evaluation by Circulating sFlt-1 Levels after Low-Dose Heparin Injection.2014

Author(s)

Journal Title

Data Source

[Journal Article] Noncardiovascular death, especially infection, is a significant cause of death in elderly patients with acutely decompensated heart failure.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nuclear accumulation of androgen receptor in gender difference of dilated cardiomyopathy due to lamin A/C mutations.2013

Author(s)

Journal Title

Data Source

[Journal Article] High mean corpuscular volume (MCV) is a new predictor of prognosis in patients with acute decompensated heart failure.2013

Author(s)

Journal Title

Data Source

[Journal Article] アルドステロン拮抗薬2010

Author(s)

Journal Title

Data Source

[Journal Article] アルドステロン拮抗薬2010

Author(s)

Journal Title

Data Source

[Journal Article] Morphological features of coronary arteries in patients with coronary spastic angina: Assessment with intracoronary optical coherence tomography2009

Author(s)

Journal Title

Data Source

[Journal Article] Regulation of aldosterone and cortisol production by the transcriptional repressor neuron restrictive silencer factor2009

Author(s)

Journal Title

Data Source

[Journal Article] Reduction of circulating soluble fms-like tyrosine kinase-1 plays a significant role in renal dysfunction-associated aggravation of atherosclerosis2009

Author(s)

Journal Title

Data Source

SATOSHI Somekawa 染川智