Harikai Naoki 張替直輝

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HARIKAI Naoki 張替直輝

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Researcher Number	90454743
Other IDs
Affiliation (Current)	2026: 日本大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2022: 日本大学, 薬学部, 教授 2013 – 2014: 日本大学, 薬学部, 准教授
Review Section/Research Field	Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Environmental and hygienic pharmacy
Keywords	Principal Investigator リガーゼ / LDR / Nusinersen / Fomivirsen / 核酸医薬品 / 遺伝子増幅法 / 食品衛生学 / 食品衛生 / 遺伝子検査

Research Projects
(2 results)
Research Products
(8 results)

Mesurement of nucleic acid medicine in biomaterials by enzymatic amplification methodsPrincipal Investigator
- Principal Investigator
  
  HARIKAI Naoki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Nihon University
Development of DNA analysis for allergenic foods in processed foodsPrincipal Investigator
- Principal Investigator
  
  HARIKAI Naoki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  Nihon University

All 2022 2021 2015 2014 Other

All Journal Article Presentation

[Journal Article] Real-time PCR method for detection of short DNA using a deoxyuridine probe and application for detection of fomivirsen.2022
- Author(s)
  Harikai N*, Tanaka Y, Miyashita S, Zaima K, Shinomiya K.
- Journal Title
  
  Biotechniques
  
  Volume: 73(6) Issue: 6 Pages: 281-287
- DOI
  10.2144/btn-2022-0068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06991
[Journal Article] 生体試料からの核酸医薬品の測定2021
- Author(s)
  張替直輝
- Journal Title
  
  BIO Clinica
  
  Volume: 36巻14号 Pages: 60-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06991
[Journal Article] Application of an Alkaline and Silica Membrane DNA Extraction Method to Detect Mitochondrial DNA in Foods2015
- Author(s)
  Harikai N, Shinomiya K.
- Journal Title
  
  Food Analytical Methods
  
  Volume: 8 Issue: 5 Pages: 1215-1224
- DOI
  10.1007/s12161-014-0002-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25860104
[Presentation] Ligase detection reactionによる生体試料からの核酸医薬品fomivirsenの定量2022
- Author(s)
  角田遥香, 張替直輝, 内山拓海, 在間一将, 四宮一総
- Organizer
  第34回バイオメディカル分析科学シンポジウム（BMAS2022）
- Data Source
  KAKENHI-PROJECT-20K06991
[Presentation] Ligase detection reactionによる核酸医薬品fomivirsenの定量2022
- Author(s)
  張替直輝，角田遙香，在間一将，四宮一総
- Organizer
  日本薬学会第142年会（名古屋）
- Data Source
  KAKENHI-PROJECT-20K06991
[Presentation] DNAの物理的劣化とPCR検出率低下との関連性に関する基礎的検討2014
- Author(s)
  張替直輝、四宮一総
- Organizer
  第74回分析化学討論会
- Place of Presentation
  福島県郡山市
- Data Source
  KAKENHI-PROJECT-25860104
[Presentation] 高温高圧負荷で劣化したλDNA試料に対するPCR法と電気泳動法での検出率の違い
- Author(s)
  張替直輝, 高田雄基, 四宮一総
- Organizer
  日本分析化学会　第75回分析化学討論会
- Place of Presentation
  山梨大学甲府キャンパス（山梨・甲府）
- Year and Date
  2015-05-23 – 2015-05-24
- Data Source
  KAKENHI-PROJECT-25860104
[Presentation] DNAの物理的劣化とPCR検出率低下との関連性に関する基礎的検討
- Author(s)
  張替直輝, 四宮一総
- Organizer
  日本分析化学会　第74回分析化学討論会
- Place of Presentation
  日本大学工学部（福島・郡山）
- Year and Date
  2014-05-24 – 2014-05-25
- Data Source
  KAKENHI-PROJECT-25860104

Harikai Naoki 張替 直輝

HARIKAI Naoki 張替 直輝

Research Projects

Research Products

Mesurement of nucleic acid medicine in biomaterials by enzymatic amplification methodsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of DNA analysis for allergenic foods in processed foodsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Real-time PCR method for detection of short DNA using a deoxyuridine probe and application for detection of fomivirsen.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 生体試料からの核酸医薬品の測定2021

Author(s)

Journal Title

Data Source

[Journal Article] Application of an Alkaline and Silica Membrane DNA Extraction Method to Detect Mitochondrial DNA in Foods2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] Ligase detection reactionによる生体試料からの核酸医薬品fomivirsenの定量2022

Author(s)

Organizer

Data Source

[Presentation] Ligase detection reactionによる核酸医薬品fomivirsenの定量2022

Author(s)

Organizer

Data Source

[Presentation] DNAの物理的劣化とPCR検出率低下との関連性に関する基礎的検討2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 高温高圧負荷で劣化したλDNA試料に対するPCR法と電気泳動法での検出率の違い

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] DNAの物理的劣化とPCR検出率低下との関連性に関する基礎的検討

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Harikai Naoki 張替直輝

HARIKAI Naoki 張替直輝