Kasahara Kousuke 笠原広介

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KASAHARA Kousuke 笠原広介

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Researcher Number	90455535
Affiliation (Current)	2025: 三重大学, 医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2025: 三重大学, 医学系研究科, 准教授 2015 – 2023: 三重大学, 医学系研究科, 准教授 2013 – 2015: 愛知県がんセンター(研究所), 腫瘍医化学部, 研究員 2007 – 2013: Div. of Biochemistry, 発がん制御研究部, Researcher 2008: 愛知県がんセンター, 発がん制御研究部, 研究員
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 49010:Pathological biochemistry-related Except Principal Investigator Cell biology / Biological Sciences / Basic Section 48030:Pharmacology-related / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 細胞周期 / 中心体 / リン酸化 / ユビキチン / 細胞増殖 / 一次線毛 / 一次繊毛 / 14-3-3 / 細胞分裂期 / Chk1 … More / p27Kip1 / p27Ki1 / 細胞分化 / インターロイキン１３ / 間葉系前駆細胞 / 骨格筋 / シグナル伝達 / 骨格筋再生 / 肥満 / ユビキチン・プロテアソーム / EGF受容体 / 受容体型チロシンキナーゼ / プロテアゾーム / 脱ユビキチン化酵素 / 癌 / プロテアソーム / Aktキナーゼ / PI3キナーゼ / Plk1キナーゼ / 細胞分裂 / 増殖生存シグナル / ユビキチン化 / 分裂期 / Polo-like kinase / プロテインキナーゼ / タンパク質リン酸化 / Plk1 / リン酸化シグナル / DNA障害チェックポイント / 分子生物学 / リン酸化修飾 / キナーゼ / DNAダメージ / 分指標的治療薬 / リン酸化シグナル伝達 / DNA損傷 / チェックポイント … More Except Principal Investigator 中間径フィラメント / 中心体 / 細胞骨格 / 一次線毛 / ケラチン / 分化 / 細胞極性 / 細胞接着 / リン酸化反応 / 染色体 / Aurora-B / Cdk1 / 抗リン酸化ペプチド抗体 / 蛋白質リン酸化 / Chk1 / 細胞周期 / 再生 / 骨格筋 / 間葉系前駆細胞 / 骨格筋再生 / EGFR抗体 / KRAS / 膵癌 / USP8 / KRAS変異 / 中間系フィラメント / aneuploidy / 染色体不安定性 / がん化 / 老化 / 細胞質分裂 / 染色体異数性 / centrosome / intermediate filament / cell polarity / cell adhesion / cytoskeleton / cell cycle / protein phosphorylation / 増殖 / 細胞内反応可視化 / 抗体遺伝子 / 中心小体 / トリコプレイン / 染色体分配 / サイクリン依存性キナーゼ1 / キナーゼ / チェックポイント / 分裂期 / プロテインキナーゼ / Plk1 / 染色体の不安定性 / 細胞分裂期 / サイクリン依存性キナーゼ / 細胞周期チェックポイント / 細胞がん化 Less

心臓線維化における一次線毛の役割と治療薬シーズの探索Principal Investigator
- Principal Investigator
  
  笠原広介
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Mie University
Elucidation of the mechanism of muscle regeneration regulated by primary cilia of mesenchymal progenitors
- Principal Investigator
  
  西村有平
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Mie University
Regulation of primary cilia formation by the ubiquitinーproteasome systemPrincipal Investigator
- Principal Investigator
  
  Kasahara Kousuke
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Mie University
Development of a new treatment for pancreatic cancer by regulating primary cilia
- Principal Investigator
  
  Yamada Reiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Mie University
Regulatory mechanism of ubiquitin-proteasome system-mediated ciliogenesisPrincipal Investigator
- Principal Investigator
  
  Kasahara Kousuke
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Mie University
The fate of aneuploid cells
- Principal Investigator
  
  Inagaki Masaki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  Mie University
The crosstalk between growth signals and mitotic signalsPrincipal Investigator
- Principal Investigator
  
  Kasahara Kousuke
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Aichi Cancer Center Research Institute
Elucidation of new functions of intermediate filaments linking a relationship between proliferation and differentiation
- Principal Investigator
  
  INAGAKI Masaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  Aichi Cancer Center Research Institute
Role of 14-3-3 family in regulation of cell cycle progressionPrincipal Investigator
- Principal Investigator
  
  KASAHARA Kousuke
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Aichi Cancer Center Research Institute
Aurora-Bを介したキナーゼカスケイドの染色体分配における役割
- Principal Investigator
  
  GOTO Hidemasa
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Aichi Cancer Center Research Institute
Antinomy of cell-cell adhesion and cell proliferation
- Principal Investigator
  
  INAGAKI Masaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Aichi Cancer Center Research Institute
生細胞でのリン酸化反応の可視化技術の開発
- Principal Investigator
  
  稲垣昌樹
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Aichi Cancer Center Research Institute
Roles of Chk1 phosphorylation in DNA damage checkpointPrincipal Investigator
- Principal Investigator
  
  KOUSUKE Kasahara
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Aichi Cancer Center Research Institute
染色体不安定性における分裂期キナーゼ群間のクロストーク機構の解明
- Principal Investigator
  
  INAGAKI Masaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Aichi Cancer Center Research Institute
Elucidation of the protein phosphorylation signaling and the regulatory mechanism of cytoskeleton
- Principal Investigator
  
  INAGAKI Masaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Aichi Cancer Center Research Institute

[Book] メディカル・サイエンス・ダイジェスト4月号2019
- Author(s)
  笠原広介、稲垣昌樹
- Total Pages
  4
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-15H02398
[Book] メディカル・サイエンス・ダイジェスト4月号2019
- Author(s)
  笠原広介、稲垣昌樹
- Total Pages
  244
- Publisher
  ニューサイエンス社
- ISBN
- Data Source
  KAKENHI-PROJECT-17K08269
[Book] 実験医学増刊知る・見る・活かす！シグナリング研究2015「一次繊毛を制御するAurora-Aシグナル」2015
- Author(s)
  笠原広介、稲垣昌樹
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-25460089
[Book] 「抗リン酸化ペプチド抗体と細胞周期研究細胞周期フロンティア2010
- Author(s)
  笠原広介、稲垣昌樹
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-20370082
[Book] 細胞周期フロンティア『抗リン酸化抗体と細胞周期研究』2010
- Author(s)
  笠原広介
- Publisher
  共立出版株式会社
- Data Source
  KAKENHI-PROJECT-22790103
[Book] 蛋白質・核酸・酵素染色体サイクル(2009年増刊号;54巻5号)2009
- Author(s)
  笠原広介
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-20790096
[Book] 蛋白質核酸酵素染色体サイクル(2009年増刊号;54巻5号)2009
- Author(s)
  笠原広介, 他
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-20055022
[Book] リン酸化によるM期制御-染色体サイクルゲノム恒常性維持、継承とダイナミクス-正井久雄、升方久夫、釣本敏樹、仁木宏典、篠原彰編2009
- Author(s)
  笠原広介、後藤英仁
- Data Source
  KAKENHI-PROJECT-20790096
[Book] 細胞の構造と分裂終期-図説分子病態学-一瀬白帝、鈴木宏治編2008
- Author(s)
  笠原広介、後藤英仁、稲垣昌樹
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20790096
[Book] 図説分子病態学4版2008
- Author(s)
  笠原広介
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20790096
[Book] 図説分子病態学(一瀬白帝、鈴木宏治編)2008
- Author(s)
  笠原広介他
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20055022
[Journal Article] Cilia‐Mediated Insulin/Akt and ST2/JNK Signaling Pathways Regulate the Recovery of Muscle Injury2022
- Author(s)
  Yamakawa Daishi、Tsuboi Junya、Kasahara Kousuke、Matsuda Chise、Nishimura Yuhei、Kodama Tatsuya、Katayama Naoyuki、Watanabe Masatoshi、Inagaki Masaki
- Journal Title
  
  Advanced Science
  
  Volume: 10 Issue: 1 Pages: 2202632-2202632
- DOI
  10.1002/advs.202202632
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09499, KAKENHI-PROJECT-20H03448, KAKENHI-PROJECT-21H02696
[Journal Article] Primary ciliary signaling: links with the cell cycle2021
- Author(s)
  Kasahara Kousuke、Inagaki Masaki
- Journal Title
  
  Trends in Cell Biology
  
  Volume: 31 Issue: 12 Pages: 954-964
- DOI
  10.1016/j.tcb.2021.07.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03448, KAKENHI-PROJECT-21H02696
[Journal Article] Primary cilia-dependent lipid raft/caveolin dynamics regulate adipogenesis2021
- Author(s)
  Yamakawa Daishi、Katoh Daisuke、Kasahara Kousuke、Shiromizu Takashi、Matsuyama Makoto、Matsuda Chise、Maeno Yumi、Watanabe Masatoshi、Nishimura Yuhei、Inagaki Masaki
- Journal Title
  
  Cell Reports
  
  Volume: 34 Issue: 10 Pages: 108817-108817
- DOI
  10.1016/j.celrep.2021.108817
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07318, KAKENHI-PROJECT-18K06890, KAKENHI-PROJECT-19K09708, KAKENHI-PROJECT-19H04205, KAKENHI-PROJECT-20H03448, KAKENHI-PROJECT-20K07356
[Journal Article] A novel CDK-independent function of p27Kip1 in preciliary vesicle trafficking during ciliogenesis2020
- Author(s)
  Yukimoto Hiroki、Miyamoto Tatsuo、Kiyono Tohru、Wang Shujie、Matsuura Shinya、Mizoguchi Akira、Katayama Naoyuki、Inagaki Masaki、Kasahara Kousuke
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 527 Issue: 3 Pages: 716-722
- DOI
  10.1016/j.bbrc.2020.05.048
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22515, KAKENHI-PROJECT-18H02624, KAKENHI-PROJECT-19H04270, KAKENHI-PROJECT-20H03448, KAKENHI-PROJECT-19K09990
[Journal Article] Targeting E3 Ubiquitin Ligases and Deubiquitinases in Ciliopathy and Cancer2020
- Author(s)
  Shiromizu Takashi、Yuge Mizuki、Kasahara Kousuke、Yamakawa Daishi、Matsui Takaaki、Bessho Yasumasa、Inagaki Masaki、Nishimura Yuhei
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 17 Pages: 5962-5962
- DOI
  10.3390/ijms21175962
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07318, KAKENHI-PROJECT-19K22433, KAKENHI-PROJECT-20H03448, KAKENHI-PROJECT-18K06890, KAKENHI-PROJECT-20K07356
[Journal Article] Intermediate filaments and IF-associated proteins: from cell architecture to cell proliferation2019
- Author(s)
  Yuhei Nishimura, Kousuke Kasahara, Masaki Inagaki
- Journal Title
  
  Proceedings of the Japan Academy, Series B
  
  Volume: 95 Issue: 8 Pages: 479-493
- DOI
  10.2183/pjab.95.034
- NAID
  130007728178
- ISSN
  0386-2208, 1349-2896
- Year and Date
  2019-10-11
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07318, KAKENHI-PROJECT-17K08269
[Journal Article] Regulation of keratin 5/14 intermediate filaments by CDK1, Aurora-B, and Rho-kinase2018
- Author(s)
  Inaba H, Yamakawa D, Tomono Y, Enomoto A, Mii S, Kasahara K, Goto H, Inagaki M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 498 Issue: 3 Pages: 544-550
- DOI
  10.1016/j.bbrc.2018.03.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08269, KAKENHI-PROJECT-17K15615, KAKENHI-PLANNED-24113005, KAKENHI-PROJECT-15H02398, KAKENHI-PROJECT-15K08324, KAKENHI-PROJECT-16K19104, KAKENHI-PROJECT-18K06927, KAKENHI-PROJECT-18K15002
[Journal Article] Primary Cilia as Signaling Hubs in Health and Disease2018
- Author(s)
  Nishimura Yuhei、Kasahara Kousuke、Shiromizu Takashi、Watanabe Masatoshi、Inagaki Masaki
- Journal Title
  
  Advanced Science
  
  Volume: 6 Issue: 1 Pages: 1801138-1801138
- DOI
  10.1002/advs.201801138
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06890, KAKENHI-PROJECT-15H02398, KAKENHI-PROJECT-16K08547, KAKENHI-PROJECT-19K07318, KAKENHI-PROJECT-17K08269
[Journal Article] Tetraploidy in cancer and its possible link to aging.2018
- Author(s)
  Tanaka K, Goto H, Nishimura Y, Kasahara K, Mizoguchi A, Inagaki M.
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 9 Pages: 2632-2640
- DOI
  10.1111/cas.13717
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08269, KAKENHI-PROJECT-15H02398, KAKENHI-PROJECT-18H02434, KAKENHI-PROJECT-16K08547, KAKENHI-PUBLICLY-18H04896
[Journal Article] EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase2018
- Author(s)
  Kasahara K, Aoki H, Kiyono T, Wang S, Kagiwada H, Yuge M, Tanaka T, Nishimura Y, Mizoguchi A, Goshima N, Inagaki M
- Journal Title
  
  Nat Commun
  
  Volume: 9 Issue: 1 Pages: 758-758
- DOI
  10.1038/s41467-018-03117-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08269, KAKENHI-PLANNED-24113005, KAKENHI-PROJECT-15H02398, KAKENHI-PROJECT-16K08547
[Journal Article] Sphingosine 1-phosphate signaling through its receptor S1P5 promotes chromosome segregation and mitotic progression2017
- Author(s)
  Andrieu G, Ledoux A, Branka S, Bocquet M, Gilhodes J, Walzer T, Kasahara K, Inagaki M, Sabbadini RA, Cuvillier O, Hatzoglou A
- Journal Title
  
  Sci Signal
  
  Volume: - Issue: 472
- DOI
  10.1126/scisignal.aah4007
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08269, KAKENHI-PLANNED-24113005, KAKENHI-PROJECT-15H02398
[Journal Article] Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein-Aurora A pathway.2016
- Author(s)
  Inaba H, Goto H, Kasahara K, Kumamoto K, Yonemura S, Inoko A, Yamano S, Wanibuchi H, He D, Goshima N, Kiyono T, Hirotsune S, Inagaki M.
- Journal Title
  
  J Cell Biol.
  
  Volume: 212 Issue: 4 Pages: 409-423
- DOI
  10.1083/jcb.201507046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15KT0086, KAKENHI-PROJECT-15K08324, KAKENHI-PROJECT-26340042, KAKENHI-PROJECT-26440111, KAKENHI-ORGANIZER-24113001, KAKENHI-PLANNED-24113005, KAKENHI-PLANNED-24113007, KAKENHI-PROJECT-25460089, KAKENHI-PROJECT-26650071, KAKENHI-PROJECT-15K20105, KAKENHI-PROJECT-15H02398
[Journal Article] Desmin phosphorylation by Cdk1 is required for efficient separation of desmin intermediate filaments in mitosis and detected in murine embryonic/newborn muscle and human rhabdomyosarcoma tissues.2016
- Author(s)
  Makihara H., Inaba H., Enomoto A., Tanaka H., Tomono Y., Ushida K., Goto M., Kurita K., Nishida Y., Kasahara K., Goto H., and Inagaki M.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 478 Issue: 3 Pages: 1323-1329
- DOI
  10.1016/j.bbrc.2016.08.122
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08324, KAKENHI-PROJECT-15H02398
[Journal Article] Phospho-Specific Antibody Probes of Intermediate Filament Proteins2016
- Author(s)
  Goto H, Tanaka H, Kasahara K, Inagaki M.
- Journal Title
  
  Methods in Enzymology
  
  Volume: 568 Pages: 85-111
- DOI
  10.1016/bs.mie.2015.07.010
- ISBN
  9780128034705
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24113005, KAKENHI-PROJECT-25460089, KAKENHI-PROJECT-26861585, KAKENHI-PROJECT-15H02398
[Journal Article] Current topics of functional links between primary cilia and cell cycle2015
- Author(s)
  Izawa I., Goto H., Kasahara K., and Inagaki M.
- Journal Title
  
  Cilia
  
  Volume: 4 Issue: 1 Pages: 12-12
- DOI
  10.1186/s13630-015-0021-1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08324, KAKENHI-PLANNED-24113005, KAKENHI-PROJECT-25460089, KAKENHI-PROJECT-26670650
[Journal Article] Novel Insights into Chk1 Regulation by Phosphorylation2015
- Author(s)
  Goto, H., Kasahara, K., and Inagaki, M.
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 40 Issue: 1 Pages: 43-50
- DOI
  10.1247/csf.14017
- NAID
  130004885867
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24113005, KAKENHI-PROJECT-24590396, KAKENHI-PROJECT-25460089, KAKENHI-PROJECT-15K08324
[Journal Article] Vimentin Phosphorylation Underlies Myofibroblast Sensitivity to Withaferin A In Vitro and during Corneal Fibrosis2015
- Author(s)
  Bargagna-Mohan P, Lei L, Thompson A, Shaw C, Kasahara K, Inagaki M, Mohan R.
- Journal Title
  
  PLoS ONE
  
  Volume: 10 Issue: 7 Pages: e0133399-e0133399
- DOI
  10.1371/journal.pone.0133399
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24113005, KAKENHI-PROJECT-25460089
[Journal Article] Ubiquitin-proteasome system controls ciliogenesis at the initial step of axoneme extension2014
- Author(s)
  Kasahara K, Kawakami Y, Kiyono T, Yonemura S, Kawamura Y, Era S, Matsuzaki F, Goshima N, Inagaki M.
- Journal Title
  
  Nat. Commun.
  
  Volume: 5 Issue: 1 Pages: 5081-5081
- DOI
  10.1038/ncomms6081
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-24113001, KAKENHI-PLANNED-24113005, KAKENHI-PLANNED-24113006, KAKENHI-PROJECT-25460089
[Journal Article] PI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition2013
- Author(s)
  Kasahara, K., Goto, H., Izawa, I., Kiyono, T., Watanabe, N., Elowe, S., Nigg, E.A. and Inagaki, M.
- Journal Title
  
  Nat. Commun.
  
  Volume: 4 Issue: 1 Pages: 1882-1882
- DOI
  10.1038/ncomms2879
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23247035, KAKENHI-ORGANIZER-24113001, KAKENHI-PLANNED-24113005, KAKENHI-PROJECT-24510320, KAKENHI-PROJECT-24590396, KAKENHI-PROJECT-24659659, KAKENHI-PROJECT-25460089
[Journal Article] PI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition2013
- Author(s)
  Kousuke Kasahara
- Journal Title
  
  Nature Communications
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790103
[Journal Article] P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferation2012
- Author(s)
  Li, P., Goto, H., Kasahara, K., Matsuyama, M., Wang, Z., Yatabe, Y., Kiyono, T. and Inagaki, M.
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 23 Pages: 1582-1592
- Data Source
  KAKENHI-PROJECT-23247035
[Journal Article] Nuclear Chk1 prevents premature mitotic entry.2011
- Author(s)
  P. Li, H. Goto, K. Kasahara, M. Matsuyama, Z. Wang, Y. Yatabe, T. Kiyono, M. Inagaki
- Journal Title
  
  J. Cell Sci.
  
  Volume: 124 Pages: 2113-2119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790103
[Journal Article] Nuclear Chk1 prevents premature mitotic entry.2011
- Author(s)
  Kousuke Kasahara, et al.
- Journal Title
  
  The Journal of Cell Science
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790103
[Journal Article] 14-3-3γ mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage2010
- Author(s)
  Kasahara, K., Goto, H., Enomoto, M., Tomono, Y., Kiyono, T. Inagaki, M
- Journal Title
  
  EMBO J 29
  
  Pages: 2802-2812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370082
[Journal Article] 14-3-3γ mediates Cdc25A proteolysis to block premature mitotic entryafter DNA damage.2010
- Author(s)
  Kasahara, K., et al.
- Journal Title
  
  EMBO J
  
  Volume: 29 Pages: 2802-2812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370082
[Journal Article] 14-3-3 gamma mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage.2010
- Author(s)
  K. Kasahara, H. Goto, M. Enomoto, Y. Tomono, T. Kiyono, M. Inagaki
- Journal Title
  
  EMBO J.
  
  Volume: 29 Pages: 2802-2812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790103
[Journal Article] Withaferin A targets intermediate filaments GFAP and vimentin in A model of retinal gliosis.2010
- Author(s)
  P. Bargagna-Mohan, R.R. Paranthan, A. Hamza, N. Dimova, B. Trucchi, C. Srinivasan, G.I. Elliott, C.G. Zhan, D.L. Lau, H. Zhu, K. Kasahara, M. Inagaki, F. Cambi, R. Mohan
- Journal Title
  
  J Biol Chem. 285
  
  Pages: 7657-7669
- Data Source
  KAKENHI-PROJECT-20790096
[Journal Article] 14-3-3 gamma mediates Cdc25A proteolysis to block premature mitoticentry after DNA damage.2010
- Author(s)
  Kousuke Kasahara, et al.
- Journal Title
  
  The EMBO Journal
  
  Volume: 29 Pages: 2802-2812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790103
[Journal Article] Withaferin A targets intermediate filaments GFAP and vimentin in A model of retinal gliosis.2010
- Author(s)
  P. Bargagna-Mohan, R.R. Paranthan, A. Hamza, N. Dimova, B. Trucchi, C. Srinivasan, G.I. Elliott, C.G. Zhan, D.L. Lau, H. Zhu, K. Kasahara, M. Inagaki, F. Cambi, R. Mohan
- Journal Title
  
  J Biol Chem.
  
  Volume: 285 Pages: 7657-7669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790103
[Journal Article] Withaferin A targets intermediate filaments glial fibrillary acidic protein and vimentin in a model of retinal gliosis2010
- Author(s)
  Bargagna-Mohan, P., Paranthan, R.R., Hamza, A., Dimova, N., Trucchi, B., Srinivasan, C., Elliott, G.I., Zhan, C.G., Lau, D.L., Zhu, H., Kasahara, K., Inagaki, M., Cambi, F. Mohan, R
- Journal Title
  
  J.Biol.Chem 285
  
  Pages: 7657-7669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370082
[Journal Article] Requirement of the SH4 and tyrosine-kinase domains but not the kinase activity of Lyn for its biosynthetic targeting to caveolin-positive Golgi membranes.2009
- Author(s)
  K. Ikeda, Y. Nakayama, M. Ishii, Y. Obata, K. Kasahara, Y. Fukumoto, N. Yamaguchi
- Journal Title
  
  Biochim. Biophys. Aca. 1790
  
  Pages: 1345-1352
- Data Source
  KAKENHI-PROJECT-20790096
[Journal Article] Differential trafficking of c-Src, Lyn, c-Yes, and Fyn is specified by the state of palmitoylation in the SH4 domain.2009
- Author(s)
  I. Sato, Y. Obata, K. Kasahara, Y. Nakayama, Y. Fukumoto, T. Yamasaki, K.K. Yokoyama, N. Yamaguchi
- Journal Title
  
  J. Cell Sci. 122
  
  Pages: 965-975
- Data Source
  KAKENHI-PROJECT-20790096
[Journal Article] A novel positive feedback loop between Cycline-dependent kinase 1 (CDK1) ad CHK1 in the nucleus during the G2/M transition.2009
- Author(s)
  M. Enomoto, H. Goto, Y. Tomono, K. Kasahara, K. Tsujimura, T. Kiyono, M. Inagaki
- Journal Title
  
  J. Biol. Chem. 284
  
  Pages: 34223-3433
- Data Source
  KAKENHI-PROJECT-20790096
[Journal Article] Nuclear localization of Src-family tyrosine kinase is required for growth factor-induced euchromatinization.2009
- Author(s)
  A. Takahashi, Y. Obata, Y. Fukumoto, Y, Nakayama, K. Kasahara, T. Kuga, Y. Higashiyama, T. Saito, K.K. Yokoyama, N. Yamaguchi
- Journal Title
  
  Exp. Cell. Re. 315
  
  Pages: 1117-1141
- Data Source
  KAKENHI-PROJECT-20790096
[Journal Article] Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during the G2/M transition2009
- Author(s)
  Enomoto, M., Goto, H., Tomono, Y., Kasahara, K., Tsujimura, K., Kiyono, T. Inagaki, M
- Journal Title
  
  J. Biol. Chem 284
  
  Pages: 34223-34230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370082
[Journal Article] Chk1 phosphorylation at Ser286 and Ser301 occurs with both stalled DNA replication and damage checkpoint stimulation2008
- Author(s)
  Ikegami, Y., Goto, H., Kiyono, T., Enomoto, M., Kasahara, K., Tomono, Y., Tozawa, K., Morita, A., Kohri, K. Inagaki, M
- Journal Title
  
  Biochem. Biophys Res.Commun 377
  
  Pages: 1227-1231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370082
[Journal Article] Nuclear localization of Lyn tyrosine kinase mediated by inhibition of its kinase activity.2008
- Author(s)
  K. Ikeda, Y. Nakayama, Y. Togashi, Y. Obata, T. Kuga, K. Kasahara, Y. Fukumoto, N. Yamaguchi.
- Journal Title
  
  Exp. Cell Re. 314
  
  Pages: 3392-3404
- Data Source
  KAKENHI-PROJECT-20790096
[Journal Article] Nuclear localization of magphinins, alternative splicing products of the human trophinin gene.2008
- Author(s)
  J. Aoyama, Y. Akazawa, K. Kasahara, Y. Higashiyama, I. Kikuchi, Y. Fukumoto, S. Saburi, Y. Nakayama, M.N. Fukuda, N. Yamaguchi.
- Journal Title
  
  J. Cel. Biochem. 103
  
  Pages: 765-777
- Data Source
  KAKENHI-PROJECT-20790096
[Journal Article] Role of Src-family kinases in formation of the cortical actin cap at the dorsal cell surface.2008
- Author(s)
  T. Kuga, M. Hoshino, Y. Nakayama, K. Kasahara, K. Ikeda, Y. Obata, A. Takahashi, Y. Higashiyama, Y, Fukumoto, N. Yamaguchi
- Journal Title
  
  Exp. Cell Re. 314
  
  Pages: 2040-2054
- Data Source
  KAKENHI-PROJECT-20790096
[Journal Article] v-Src and c-Src, nonpalmitoylated Src-family kinases, control lysosome distribution via Rab7 in an SH2 domain-dependent manner.2008
- Author(s)
  K. Kasahara, Y. Nakayama, N. Yamaguchi.
- Journal Title
  
  Caner Lett. 262
  
  Pages: 19-27
- Data Source
  KAKENHI-PROJECT-20790096
[Journal Article] Chk1 phosphorylation at Ser286 and Ser301 occurs with both stalled DNA replication and damage checkpoint stimulation.2008
- Author(s)
  Y. Ikegami, H. Goto, T. Kiyono, M. Enomoto, K Kasahara, Y. Tomono, K. Tozawa, A. Morita, K. Kohri, M. Inagaki
- Journal Title
  
  Biochem. Biophys. Res. Commun. 377
  
  Pages: 1227-1231
- Data Source
  KAKENHI-PROJECT-20790096
[Journal Article] v-Src and c-Src, nonpalmitoylated Src-family kinases, control lysosome distribution via Rab7 in SH2 domain-dependent manner2008
- Author(s)
  Kousuke Kasahara
- Journal Title
  
  Cancer Letters 262
  
  Pages: 19-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790096
[Journal Article] PI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3gamma and is required fo r metaphase-anaphase transition.
- Author(s)
  K. Kasahara, H. Goto, T. Kiyono, N. Watanabe, S. Elowe, E.A. Nigg, M. Inagaki
- Journal Title
  
  Nat. Commn.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790103
[Journal Article] Nuclear Chkl prevents premature mitotic entry
- Author(s)
  Matsuyama, M., Goto, H., Kasahara, K., Kawakami, Y., Nakanishi, M., Kiyono, T., Goshima, N. Inagaki, M
- Journal Title
  
  J.Cell Sci. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370082
[Presentation] ユビキチン修飾系による一次線毛動態制御と疾患治療2021
- Author(s)
  笠原広介, 山川大史、稲垣昌樹
- Organizer
  第25回日本がん分子標的治療学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03448
[Presentation] 一次繊毛による細胞増殖・分化制御と疾患2021
- Author(s)
  笠原広介, 山川大史, 稲垣昌樹
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03448
[Presentation] 一次線毛と細胞増殖・分化・がん化2020
- Author(s)
  稲垣昌樹、笠原広介, 山川大史、松田知世、渡邉昌俊
- Organizer
  第79回日本癌学会学術総会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03448
[Presentation] 一次線毛の形成動態によるがん細胞増殖制御機構の解明2018
- Author(s)
  笠原広介, 稲垣昌樹
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08269
[Presentation] 一次線毛の形成動態によるがん細胞増殖制御機構の解明2018
- Author(s)
  笠原広介, 稲垣昌樹
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02398
[Presentation] 増殖因子による一次繊毛の形成抑制メカニズム2017
- Author(s)
  笠原広介、青木啓将、清野透、山川大史、稲垣昌樹
- Organizer
  第69回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-17K08269
[Presentation] Primary cilia and cell cycle2016
- Author(s)
  Inagaki M, Kasahara K.
- Organizer
  The 28th CDB meeting “Cilia and Centrosomes”
- Place of Presentation
  RIKEN CDB (Kobe, Japan)
- Year and Date
  2016-11-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02398
[Presentation] Primary cilia and cell cycle2016
- Author(s)
  Inagaki M. and Kasahara K.
- Organizer
  The 28th CDB meeting "Cilia and Centrosomes"
- Place of Presentation
  RIKEN CDB (Kobe, Japan)
- Year and Date
  2016-11-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02398
[Presentation] 脱ユビキチン化酵素Usp8による１次シリアの制御2015
- Author(s)
  笠原広介、青木啓将、田中宏樹、清野透、高坂美恵子、福田枝里子、五島直樹、稲垣昌樹
- Organizer
  第38回日本分子生物学会・第88回日本生化学会合同大会（BMB2015）
- Place of Presentation
  神戸ポートピアアイランド（神戸市）
- Year and Date
  2015-12-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460089
[Presentation] The PI3K-Akt pathway controls mitotic progression through Plk12012
- Author(s)
  笠原広介
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ホテルロイトン札幌（札幌）
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] Emerging role of the ubiqutiin-proteasome system in primary cilia assembly.2012
- Author(s)
  笠原広介
- Organizer
  GCOE第五回NAGOYAグローバルリトリート
- Place of Presentation
  あいち健康プラザ・大府
- Year and Date
  2012-02-01
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] Novel mitotic signalling crosstalk between PI3K-Akt pathway and Plk1.2012
- Author(s)
  Kasahara, K.
- Organizer
  Global CEO the 4th International Symposium "Global COE Symposium on Nuro-Tumor Biology and Medicine"
- Place of Presentation
  Westin Nagoya Castle, Nagoya
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] PI3K-Akt pathway controls P olo-like kinase 1 (Plk1).2012
- Author(s)
  笠原広介、後藤英仁、井澤一郎、渡邉信元、清野透、稲垣昌樹
- Organizer
  第45回日本発生生物学会・第64回日本細胞生物学会合同大会・ポスターフラッシュトーク
- Place of Presentation
  国際会議場・神戸
- Year and Date
  2012-05-28
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] Novel mitotic signaling pathway from Akt/PKB to Polo-like kinase 1 (Plk1)2012
- Author(s)
  笠原広介
- Organizer
  第4回NAGOYAグローバルリトリート
- Place of Presentation
  あいち健康プラザ(愛知・大府)
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferation.2012
- Author(s)
  後藤英仁、李萍、笠原広介、松山真、王中華・谷田部恭、清野透、稲垣昌樹
- Organizer
  第45回日本発生生物学会・第64回日本細胞生物学会合同大会・ワークショップ
- Place of Presentation
  国際会議場・神戸
- Year and Date
  2012-05-30
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] Novel mitotic signalling crosstalk between PI3K -Akt pathway and Plk1.2012
- Author(s)
  Goto H, Kasahara K, Izawa I, Kiyono T, Watanabe N, Elowe S, Nigg EA, Inagaki M.
- Organizer
  The 52nd Annual Meeting of the American Society for Cell Biology.
- Place of Presentation
  Moscone Center, San Francisco
- Year and Date
  2012-10-17
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] pathway controls mitotic progression through Plk1.2012
- Author(s)
  笠原広介、後藤英仁、井澤一郎、渡邉信元、清野透、稲垣昌樹
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌ホテル・札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferation.2012
- Author(s)
  後藤英仁、李萍、笠原広介、松山真、王中華・谷田部恭、清野透、稲垣昌樹
- Organizer
  第45回日本発生生物学会・第64回日本細胞生物学会合同大会
- Place of Presentation
  国際会議場・神戸
- Year and Date
  2012-05-29
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] PI3K-Akt pathway controls Polo -like kinase 1 (Plk1).2012
- Author(s)
  笠原広介、後藤英仁、井澤一郎、渡邉信元、清野透、稲垣昌樹
- Organizer
  第45回日本発生生物学会・第64回日本細胞生物学会合同大会・ポスターフラッシュトーク
- Place of Presentation
  国際会議場・神戸
- Year and Date
  2012-05-28
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] Complex formation between Plk1 and 14-3-3 gamma is essential for metaphase-anaphase transition.2012
- Author(s)
  Kousuke Kasahara、Masaki Inagaki
- Organizer
  Mini-symposium "STRESS SIGNALS & RESPONSES"
- Place of Presentation
  Abo University, Turku, Finland
- Year and Date
  2012-09-27
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] p90 RSK (Ribosomal S6 Kinase) によるChk1-Ser280のリン酸化修飾.2011
- Author(s)
  李萍、後藤英仁、松山真、笠原広介、村上善子、谷田部恭、清野透、稲垣昌樹
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜・横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] Chk1 phosphorylation by p90 Ribosomal S6 kinase (p90 RSK).2011
- Author(s)
  Goto, H., Li, P., Kiyono, T., Matsuyama, M., Kasahara, K., Murakami, Y., Yatabe, Y. and Inagaki, M.
- Organizer
  The 51th Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  Colorado Convention Center, Denver
- Year and Date
  2011-12-04
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] 14-3-3 gamma activates Plk1 and controls mitotic progression.2011
- Author(s)
  Kasahara, K., Goto, H., Izawa and Inagaki, M.
- Organizer
  The 70th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya Congress Center, Nagoya
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] 新規リン酸化反応による分裂キナーゼPlk1の活性制御メカニズム.2011
- Author(s)
  笠原広介、後藤英仁、井澤一郎、渡邉信元、清野透、稲垣昌樹
- Organizer
  第34回日本分子生物学会年会・ワークショップ
- Place of Presentation
  パシフィコ横浜・横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] Chk1 phosphorylation at Ser280 by p90 ribosomal kinase (p90 RSK).2011
- Author(s)
  Goto, H., Li, P., Yatabe, Y., Kasahara, K., Matsuyama, M., Kiyono, T. and Inagaki, M.
- Organizer
  The 70th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya Congress Center, Nagoya
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] 14-3-3 gamma activates Plk1 and controls mitotic progression2011
- Author(s)
  笠原広介
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] 中心体ではなく核に局在するChk1が細胞周期において重要な役割を果たす.2010
- Author(s)
  松山誠、後藤英仁、笠原広介、川上和孝、井澤一郎、榎本将人、小堀恭子、中西真、清野透、五島直樹、稲垣昌樹
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  国際会議場・神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] PP2A antagonizes Chk1 phosphorylation by ATR through 14-3-3 proteins in DNA damage checkpoint.2010
- Author(s)
  笠原広介、後藤英仁、清野透、稲垣昌樹
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場・大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] PP2A antagonizes Chk1 phosphorylation by ATR through 14-3-3 proteins in DNA damage checkpoint.2010
- Author(s)
  笠原広介
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] 増殖刺激応答におけるChk1-Ser280のリン酸化反応.2010
- Author(s)
  李萍、後藤英仁、笠原広介、清野透、稲垣昌樹
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場・大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] 抗リン酸化ペプチド抗体とチェックポイントシグナル2010
- Author(s)
  稲垣昌樹, 笠原広介, 李萍, 後藤英仁
- Organizer
  H22生化学会中部支部例会
- Place of Presentation
  (名古屋)[シンポジウム]
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-20370082
[Presentation] 増殖刺激応答におけるChk1-Ser280のリン酸化反応.2010
- Author(s)
  李萍、後藤英仁、笠原広介、松山誠、清野透、稲垣昌樹
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  国際会議場・神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] The association between autophosphorylated Chk1 and 14-3-3gamma is required for Chk1 function in DNA damage checkpoint2009
- Author(s)
  笠原広介, 後藤英仁, 榎本将人, 友野靖子, 清野透, 稲垣昌樹
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790096
[Presentation] 多彩なリン酸化によってチェックポイントキナーゼ1(Chk1)は機能修飾される2009
- Author(s)
  笠原広介
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20790096
[Presentation] 多彩なリン酸化によってチェックポイントキナーゼ1(Chk1)は機能修飾される2009
- Author(s)
  笠原広介, 後藤英仁, 稲垣昌樹
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  (横浜)[シンポジウム]
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20370082
[Presentation] 14-3-3γmediates Cdc25A proteolysis to induce S and G2 arrest after DNA damage.2009
- Author(s)
  Goto, H., Kasahara, K., Tomono, Y., Enomoto, M., Kiyono, T., Inagaki, M.
- Organizer
  The 49th Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-20790096
[Presentation] G2/M期におけるCdk1によるChk1の制御機構の解析2009
- Author(s)
  榎本将人, 後藤英仁, 友野靖子, 笠原広介, 辻村邦夫, 清野透, 稲垣昌樹
- Organizer
  第82回日本生化学大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20790096
[Presentation] 多彩なリン酸化によってチェックポイントキナーゼ1(Chk1)は機能修飾される2009
- Author(s)
  笠原広介、後藤英仁、稲垣昌樹
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20790096
[Presentation] The association between autophosphorylated Chk1 and 14-3-3 gamma is required for Chk1 function in DNA damage checkpoint2009
- Author(s)
  笠原広介
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋・名古屋国際会議場
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-20790096
[Presentation] 14-3-3γmediates Cdc25A proteolysis to induce S and G2 arrest after DNA damage.2009
- Author(s)
  Kasahara, K.
- Organizer
  Global Center of Excellence (COE) Program 2nd International Symposium "Signaling of Cancer Cells"
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-20790096
[Presentation] Regulatory mechanism of Chk1 by its autophosphoryaltion in checkpoint response2009
- Author(s)
  Kasahara, K.
- Organizer
  Global Center of Excellence (COE) Program 1st International Symposium "Signaling of Cancer Cells"
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-20790096
[Presentation] Negative feedback regulation of Chk1 by its own kinase acitivity2008
- Author(s)
  笠原広介、後藤英仁、榎本将人、池上要介、友野靖子、稲垣昌樹
- Organizer
  2008年BMB2008(第31回日本分子生物学会年会・第81回日本生化学大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20790096
[Presentation] Negative feedback regulation of Chk1 by its own kinase activity2008
- Author(s)
  笠原広介、後藤英仁、榎本将人、池上要介、友野靖子、稲垣昌樹
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20790096
[Presentation] Autophosphorylation of Chk1 in checkpoint response2008
- Author(s)
  笠原広介、後藤英仁、池上要介、榎本将人、友野靖子、稲垣昌樹
- Organizer
  2008年第60回日本細胞生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20790096
[Presentation] 細胞増殖因子刺激により誘導されるユークロマチン化における核局在Src型チロシンキナーゼの役割2008
- Author(s)
  高橋明格、福本泰典、中山祐治、笠原広介、久家貴寿、小幡裕希、東山幸弘、山口直人
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20790096
[Presentation] Ser-296 phosphorylation of Chk1 in checkpoint response2008
- Author(s)
  笠原広介、後藤英仁、池上要介、榎本将人、友野靖子、稲垣昌樹
- Organizer
  2008年第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790096
[Presentation] Chk1 phosphorylaiton by Cyclin-dependent kinase 1 promotes mitotic entry2008
- Author(s)
  Goto H., Enomoto M., Tomono Y., Kasahara K., Ikegami Y., Tsujimura K., Kiyono T., Inagaki M.
- Organizer
  2008 American Society for Cell Biology
- Data Source
  KAKENHI-PROJECT-20790096
[Presentation] Emerging role of the ubiquitin-proteasome pathway in primary cilia assembly
- Author(s)
  Kousuke Kasahara, Naoki Goshima, Fumio Matsuzaki, Masaki Inagaki
- Organizer
  The 25th CDB meeting “Cilia and Centrosomes, from Fertilization to Cancer”
- Place of Presentation
  RIEKN CDB, Kobe
- Invited
- Data Source
  KAKENHI-PROJECT-25460089
[Presentation] Ubiquitin-proteasome system controls primary ciliogenesis at the initial step of axoneme extension
- Author(s)
  笠原広介
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25460089
[Presentation] Chk1 phosphorylation by Cyclin-dependent kinases (Cdks)
- Author(s)
  Enomoto, M., Goto, H., Ikegami, Y., Kasahara, K., Tomono, Y., Tsujimura, K., Kiyono, T., Inagaki, M.
- Organizer
  International Symposium on Chromosome Dynamics in Ise
- Place of Presentation
  Shima
- Data Source
  KAKENHI-PROJECT-20790096
[Presentation] PI3K-Akt pathway controls Polo-like kinase 1 (Plk1)
- Author(s)
  笠原広介
- Organizer
  第45回日本発生生物学会・第64回日本細胞生物学会合同大会
- Place of Presentation
  神戸国際会議場（神戸）
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] Emerging role of the ubiqutiin-proteasome system in assmembly of primary cilium
- Author(s)
  笠原広介、川上和孝、河村義史、衣斐美歩、五島直樹、稲垣昌樹
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  ウイング愛知、名古屋
- Data Source
  KAKENHI-PROJECT-25460089
[Presentation] Complex formation between Plk1 and 14-3-3 gamma is essential for metapahse to anaphase transition
- Author(s)
  笠原広介
- Organizer
  Mini-Symposium on “Stress Signals & Responses”, Abo Akademi University Center of Excellence “Cell stress and Molecular Aging”
- Place of Presentation
  オーボ大学（フィンランド・トゥルク）
- Invited
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] A Cul3-based ubiquitin E3 ligase controls primary cilia assembly through degradation of Trichoplein
- Author(s)
  笠原広介、川上和孝、河村義史、衣斐美歩、清野透、五島直樹、松崎文雄、稲垣昌樹
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-25460089
[Presentation] Novel mitotic signalling crosstalk between PI3K-Akt pathway and Plk1
- Author(s)
  笠原広介
- Organizer
  Global COE the　4th International Symposium
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-22790103
[Presentation] Chk1 phosphorylation by Cyclin-dependent kinase 1 promotes mitotic entry
- Author(s)
  Goto, H., Enomoto, M. Tomono, Y., Kasahara, K., Ikegami, Y., Tsujimura, K., Kiyono, T. Inagaki, M.
- Organizer
  The 48th Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-20790096

1. INAGAKI Masaki (30183007)

# of Collaborated Projects: 6 results

# of Collaborated Products: 20 results
2. INOKO Akihito (30393127)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. GOTO Hidemasa (20393126)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
4. IZAWA Ichiro (20311441)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. 田中宏樹 (20725452)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 白水崇 (00582678)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. 山川大史 (20631097)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
8. Yamada Reiko (80571629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 西村有平 (30303720)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. KAWAMOTO Eriko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 松田知世

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 渡辺昌俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 松崎文雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 五島直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 米村重信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 松浦伸也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 宮本達雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kasahara Kousuke 笠原 広介

KASAHARA Kousuke 笠原 広介

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心臓線維化における一次線毛の役割と治療薬シーズの探索Principal Investigator

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Regulation of primary cilia formation by the ubiquitinーproteasome systemPrincipal Investigator

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Regulatory mechanism of ubiquitin-proteasome system-mediated ciliogenesisPrincipal Investigator

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The crosstalk between growth signals and mitotic signalsPrincipal Investigator

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Role of 14-3-3 family in regulation of cell cycle progressionPrincipal Investigator

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Roles of Chk1 phosphorylation in DNA damage checkpointPrincipal Investigator

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Kasahara Kousuke 笠原広介

KASAHARA Kousuke 笠原広介

[Book] 実験医学増刊知る・見る・活かす！シグナリング研究2015「一次繊毛を制御するAurora-Aシグナル」2015

[Book] 図説分子病態学4版2008

[Book] 図説分子病態学(一瀬白帝、鈴木宏治編)2008