KAWAKAMI Hiroshi 川上浩

… Alternative Names

川上浩カワカミヒロシ

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Researcher Number	90458860
Affiliation (Current)	2026: 東京大学, 大学院農学生命科学研究科(農学部), 特任研究員
Affiliation (based on the past Project Information) *help	2009 – 2021: Kyoritsu Women's University, 家政学部, 教授
Review Section/Research Field	Principal Investigator Food science / Basic Section 38050:Food sciences-related Except Principal Investigator Basic Section 38050:Food sciences-related / 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator 食品機能 / 生理活性 / 蛋白質 / 食品 / アフィニティー精製 / 唾液タンパク質 / 鉄代謝 / 抗炎症作用 / 生理機能 / 乳タンパク質 … More Except Principal Investigator … More ラクトフェリン / ペプチド医薬開発基盤 / 生体防御 / 食品タンパク質 / 表層タンパク質 / 外被タンパク質 / 複合体構造解析 / 虫歯菌表層タンパク質 / 唾液凝集素タンパク質 / 相互作用阻害 / 相互作用解析 / NV外被タンパク質P domain / HCV外被タンパク質E2 / CD81 / 共結晶化 / 分子間相互作用 / 複合体モデル構築 / 結晶構造解析 / 等温滴定熱測定 / プルダウンアッセイ / 作用機構可視化 / 立体構造解析 / 分子間相互作用解析 / 唾液凝集素 / 虫歯菌 / ノロウイルス / C型肝炎ウイルス / 血栓 / NETｓ / 腎炎 / 血管炎 / 自己免疫 / 炎症 / 好中球細胞外トラップ / 好中球 / vasculitis / autoimmune / lactoferrin / inflammation / neutrophil Less

多機能性乳タンパク質結合ペプチド群の生理活性発現機構とその応用に関する研究Principal Investigator
- Principal Investigator
  
  川上浩
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Kyoritsu Women's University
Structural basis for antiviral and antibacterial activities of milk protein lactoferrin and its activity enhancement
- Principal Investigator
  
  Nagata Koji
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  The University of Tokyo
Biological activities of multifunctional protein in milk and their applicationsPrincipal Investigator
- Principal Investigator
  
  Kawakami Hiroshi
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Kyoritsu Women's University
Proteomic analysis of bioactive substances coexisted with a multifunctional milk protein and application of the biological functionsPrincipal Investigator
- Principal Investigator
  
  KAWAKAMI HIROSHI
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Kyoritsu Women's University
Regulation of neutrophil extracellular traps via fenton reaction and its application to the treatment of refractory autoimmune vasculitis
- Principal Investigator
  
  HIRAHASHI Junichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Keio University
  The University of Tokyo
Biochemical properties of a multifunctional protein in milk and its applicationPrincipal Investigator
- Principal Investigator
  
  KAWAKAMI Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Kyoritsu Women's University

All 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] ヒトの基礎生化学2021
- Author(s)
  川上　浩
- Total Pages
  259
- Publisher
  アイ・ケイコーポレーション
- ISBN
  9784874923320
- Data Source
  KAKENHI-PROJECT-16K07745
[Book] 天然系抗菌・防カビ剤の開発と応用2019
- Author(s)
  永田宏次, 川上　浩
- Total Pages
  233
- Publisher
  シーエムシー出版
- ISBN
  9784781312606
- Data Source
  KAKENHI-PROJECT-16K07745
[Book] 天然系抗菌・防カビ剤の開発と応用（第11章　乳タンパク質ラクトフェリンの抗ウイルス・抗菌作用と活性増強）2019
- Author(s)
  監修坂上吉一（第11章執筆永田宏次、川上浩）
- Total Pages
  233
- Publisher
  シーエムシー出版
- ISBN
  9784781312606
- Data Source
  KAKENHI-PROJECT-18H02151
[Journal Article] ラクトフェリンの免疫調節機能2020
- Author(s)
  川上　浩
- Journal Title
  
  食品と開発
  
  Volume: 55 (10) Pages: 4-7
- Data Source
  KAKENHI-PROJECT-16K07745
[Journal Article] Lactoferrin Suppresses Neutrophil Extracellular Traps Release in Inflammation.2016
- Author(s)
  Okubo K, Kamiya M, Urano Y, Nishi H, Herter JM, Mayadas T, Hirohama D, Suzuki K, Kawakami H, Tanaka M, Kurosawa M, Kagaya S, Hishikawa K, Nangaku M, Fujita T, Hayashi M, Hirahashi J.
- Journal Title
  
  EBioMedicine
  
  Volume: 10 Pages: 204-215
- DOI
  10.1016/j.ebiom.2016.07.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-16H06751, KAKENHI-PROJECT-15K09459, KAKENHI-PROJECT-16K07745
[Journal Article] Effects of enteric-coated lactoferrin supplementation on the immune function of elderly individuals: a randomized double-blind, placebo-controlled trial.2015
- Author(s)
  H. Kawakami et al.
- Journal Title
  
  International Dairy Journal
  
  Volume: 47 Pages: 79-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580197
[Journal Article] Effects of enteric-coated lactoferrin supplementation on the immune function of elderly individuals: A randomised, double-blind, placebo-controlled trial2015
- Author(s)
  H. Kawakami, H. Park, S. Park, H. Kuwata, R.J. Shephard, Y. Aoyagi
- Journal Title
  
  International Dairy Journal
  
  Volume: 47 Pages: 79-85
- DOI
  10.1016/j.idairyj.2015.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300240, KAKENHI-PROJECT-24580197
[Journal Article] Physicochemical and biochemical characteristics of basic proteins in milk2013
- Author(s)
  H. Kawakami
- Journal Title
  
  Milk Sci.
  
  Volume: 62 Pages: 85-104
- NAID
  130004647743
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580197
[Journal Article] Proteomic analysis of impurities coexisted with lactoferrin2013
- Author(s)
  H. Kawakami et al.
- Journal Title
  
  Milk Sci.
  
  Volume: 62 Pages: 29-37
- NAID
  130004647739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580197
[Presentation] Overview: Potential of milk proteins to promote human health2019
- Author(s)
  Hiroshi Kawakami
- Organizer
  International Dairy Federation World Dairy Summit 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07745
[Presentation] ウシラクトフェリンによるC型肝炎ウイルス感染抑制の分子機構解析2019
- Author(s)
  三好光子、黎藜、片山幸江、盧翌、岡本研、鈴木道生、川上　浩、永田宏次
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-16K07745
[Presentation] Screening for infection inhibitors of human norovirus GII.17 from food ingredients2018
- Author(s)
  Li, L., Shojima, T., Lu, L., Katayama, Y., Suzuki, M., Kawakami, H., Nagata, K
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-16K07745
[Presentation] Analyzing the molecular mechanism of inhibition of bovine norovirus infection by bovine lactoferrin2018
- Author(s)
  Hu, C., Shojima, T., Katayama, Y., Suzuki, M., Kawakami, H., Nagata, K.
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-16K07745
[Presentation] ラクトフェリンによるC型肝炎ウイルス感染防御の構造基盤解析2018
- Author(s)
  三好光子、李彦君、黎藜、陸鵬、張迷敏、生島智樹、盧翌、岡本研、片山幸江、鈴木道生、川上　浩、永田宏次
- Organizer
  日本ラクトフェリン学会
- Data Source
  KAKENHI-PROJECT-16K07745
[Presentation] ラクトフェリンによるC型肝炎ウイルス感染防御の構造基盤解析2018
- Author(s)
  三好光子、李彦君、黎藜、陸鵬、張迷敏、生島智樹、盧翌、岡本研、片山幸江、鈴木道生、川上浩、永田宏次
- Organizer
  日本ラクトフェリン学会
- Data Source
  KAKENHI-PROJECT-18H02151
[Presentation] ラクトフェリンの齲蝕防止作用の構造基盤解析2018
- Author(s)
  胡超越、福田玖瑠未、大野陽介、陸鵬、生島智樹、盧翌、岡本研、片山幸江、鈴木道生、川上浩、永田宏次
- Organizer
  日本ラクトフェリン学会
- Data Source
  KAKENHI-PROJECT-18H02151
[Presentation] ラクトフェリンの齲蝕防止作用の構造基盤解析2018
- Author(s)
  胡超越、福田玖瑠未、大野陽介、陸鵬、生島智樹、盧翌、岡本研、片山幸江、鈴木道生、川上　浩、永田宏次
- Organizer
  日本ラクトフェリン学会
- Data Source
  KAKENHI-PROJECT-16K07745
[Presentation] 抗貧血薬候補鉄配位ウシラクトフェリンのpH依存による会合機構2017
- Author(s)
  松村義隆、山口智大、清野翔平、川上　浩、田之倉優、小島正樹
- Organizer
  第34回PFシンポジウム
- Place of Presentation
  つくば
- Year and Date
  2017-03-14
- Data Source
  KAKENHI-PROJECT-16K07745
[Presentation] 抗貧血薬候補ウシラクトフェリンの酸性pHから中性pHの会合機構2016
- Author(s)
  松村義隆、山口智大、清野翔平、川上　浩、田之倉優、小島正樹
- Organizer
  第16回日本蛋白質科学会
- Place of Presentation
  福岡
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PROJECT-16K07745
[Presentation] 母乳の不思議：何故，母乳栄養児に貧血が少ないのか2015
- Author(s)
  川上浩
- Organizer
  第60回日本透析医学会
- Place of Presentation
  横浜
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-24580197
[Presentation] 母乳の神秘を解き明かす：母乳栄養児に貧血が少ないのは何故なのか2015
- Author(s)
  川上浩
- Organizer
  第18回日本腎不全看護学会
- Place of Presentation
  名古屋
- Year and Date
  2015-11-14
- Data Source
  KAKENHI-PROJECT-24580197
[Presentation] Effect of enteric-coated lactoferrin supplementation on immune makers in serum of healthy elderly individuals: a randomized, double-blind, placebo-controlled trial2013
- Author(s)
  H. Kawakami et al.
- Organizer
  International Conference on Lactoferrin
- Place of Presentation
  Roma, Italy
- Data Source
  KAKENHI-PROJECT-24580197
[Presentation] 腸溶性ラクトフェリンの摂取が高齢者の免疫機能に及ぼす影響2012
- Author(s)
  川上浩ほか
- Organizer
  日本食品免疫学会　2012年度大会
- Place of Presentation
  新橋
- Data Source
  KAKENHI-PROJECT-24580197
[Presentation] 腸溶性ラクトフェリンの摂取が高齢者の免疫機能に及ぼす影響2012
- Author(s)
  川上浩ほか
- Organizer
  酪農科学シンポジウム　平成24年度大会
- Place of Presentation
  市ヶ谷
- Data Source
  KAKENHI-PROJECT-24580197
[Presentation] 高齢者の免疫機能に及ぼす腸溶性LFの効果2011
- Author(s)
  川上浩
- Organizer
  酪農科学シンポジウム
- Place of Presentation
  フォレスト仙台
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21580153
[Presentation] Effects of enteric-coated LF supplementation of the immune status of healthy elderly individuals : a randomized, double-blind, placebo-controlled trial2011
- Author(s)
  Hiroshi Kawakami
- Organizer
  10^<th> International Conference on Lactoferrin
- Place of Presentation
  EL CID Mazatlan (Mexico)
- Year and Date
  2011-05-08
- Data Source
  KAKENHI-PROJECT-21580153
[Presentation] 高齢者の免疫機能における腸溶性LFの効果2011
- Author(s)
  川上浩
- Organizer
  酪農科学シンポジウム
- Place of Presentation
  フォレスト仙台(仙台)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21580153
[Presentation] Effect of enteric coated LF supplementation of the immune status of healthy elderly individuals2011
- Author(s)
  Hiroshi Kawakami
- Organizer
  International Conference on Lactoferrin
- Place of Presentation
  HOTEL EL CID Mazatlan Mexico
- Year and Date
  2011-05-08
- Data Source
  KAKENHI-PROJECT-21580153
[Presentation] Effect of enteric-coated lactoferrin supplementation on immune status in the elderly.
- Author(s)
  H. Kawakami et al.
- Organizer
  Annual Conference & Exhibition: Functional Foods, Nutraceuticals, Natural Health Products, and Dietary Supplements
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2014-10-14 – 2014-10-17
- Data Source
  KAKENHI-PROJECT-24580197

1. HIRAHASHI Junichi (70296573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. URANO Yasuteru (20292956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. OKUBO Koshu (60749125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KAMIYA Mako (90596462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Nagata Koji (30280788)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 鈴木道生 (10647655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. NANGAKU Masaomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. PARK Hyuntae

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAWAKAMI Hiroshi 川上 浩

川上 浩 カワカミ ヒロシ

Research Projects

Research Products

Co-Researchers

多機能性乳タンパク質結合ペプチド群の生理活性発現機構とその応用に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural basis for antiviral and antibacterial activities of milk protein lactoferrin and its activity enhancement

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Biological activities of multifunctional protein in milk and their applicationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Proteomic analysis of bioactive substances coexisted with a multifunctional milk protein and application of the biological functionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of neutrophil extracellular traps via fenton reaction and its application to the treatment of refractory autoimmune vasculitis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Biochemical properties of a multifunctional protein in milk and its applicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] ヒトの基礎生化学2021

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 天然系抗菌・防カビ剤の開発と応用2019

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 天然系抗菌・防カビ剤の開発と応用（第11章 乳タンパク質ラクトフェリンの抗ウイルス・抗菌作用と活性増強）2019

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] ラクトフェリンの免疫調節機能2020

Author(s)

Journal Title

Data Source

[Journal Article] Lactoferrin Suppresses Neutrophil Extracellular Traps Release in Inflammation.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of enteric-coated lactoferrin supplementation on the immune function of elderly individuals: a randomized double-blind, placebo-controlled trial.2015

Author(s)

Journal Title

Data Source

[Journal Article] Effects of enteric-coated lactoferrin supplementation on the immune function of elderly individuals: A randomised, double-blind, placebo-controlled trial2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Physicochemical and biochemical characteristics of basic proteins in milk2013

Author(s)

Journal Title

KAWAKAMI Hiroshi 川上浩

川上浩カワカミヒロシ

[Book] 天然系抗菌・防カビ剤の開発と応用（第11章　乳タンパク質ラクトフェリンの抗ウイルス・抗菌作用と活性増強）2019