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HIDA Tokimasa  肥田 時征

ORCIDConnect your ORCID iD *help
… Alternative Names

肥田 時征  ヒダ トキマサ

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Researcher Number 90464487
Other IDs
Affiliation (Current) 2025: 札幌医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2024: 札幌医科大学, 医学部, 准教授
2021: 札幌医科大学, 医学部, 講師
2015: 札幌医科大学, 医学部皮膚科学講座, 講師
2014 – 2015: 札幌医科大学, 医学部, 講師
2008 – 2013: Sapporo Medical University, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 53050:Dermatology-related / Cell biology / Dermatology
Except Principal Investigator
Dermatology
Keywords
Principal Investigator
ドライバー変異 / メラノーマ / シーケンス / 変異 / 悪性黒色腫 / 融合遺伝子 / 遺伝子 / 循環腫瘍細胞 / コピー数多型 / 構造多型 / 細胞生物学 / メラノソーム / 癌 … More
Except Principal Investigator
… More microRNA (miRNA) / メチル化 / インターフェロン-β (INF-β) / ドライバー変異 / 5-aza-2'-cytidine / インターフェロンbeta / 次世代シーケンス / microRNA (miR) / 5-aza-2’-cytidine / DNAメチル化 / アポトーシス / インターフェロン-β / 悪性黒色腫 (メラノーマ) / B16F1メラノーマ細胞転移 / 悪性黒色腫 SIRT1 / 悪性黒色腫(メラノーマ) / lamellipodium / 転移 / 細胞移動 / B16F1メラノーマ細胞 / SIRT1 / メラノーマ / 悪性黒色腫 / 色素細胞学 / 分子腫瘍学 Less
  • Research Projects

    (6 results)
  • Research Products

    (47 results)
  • Co-Researchers

    (8 People)
  •  Preemptive medicine for Japanese melanoma through comprehensive analysis of tumor genome and circulating tumor cellsPrincipal Investigator

    • Principal Investigator
      肥田 時征
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Sapporo Medical University
  •  Comprehensive analysis of genetic mutations and fusions in Japanese melanomaPrincipal Investigator

    • Principal Investigator
      肥田 時征
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Sapporo Medical University
  •  Identification and analysis of tumor-associated genes of melanoma by functional assay

    • Principal Investigator
      Yamashita Toshiharu
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Sapporo Medical University
  •  Analysis of melanosome transfer between melanocytes and keratinocytesPrincipal Investigator

    • Principal Investigator
      HIDA Tokimasa
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cell biology
    • Research Institution
      Sapporo Medical University
  •  Development of novel melanoma therapy targeting SIRT1

    • Principal Investigator
      YAMASITA Tosiharu
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Sapporo Medical University
  •  Analysis of the drug sensitivity and the genetic alteration of melanomaPrincipal Investigator

    • Principal Investigator
      HIDA Tokimasa
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      Sapporo Medical University

All 2021 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

  • [Book] 皮膚科臨床アセット152013

    • Author(s)
      肥田時征,山下利春
    • Total Pages
      4
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-23770233
  • [Book] 貧血母斑.皮膚科臨床アセット15-母斑と母斑症-2013

    • Author(s)
      肥田時征,山下利春
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-23770233
  • [Journal Article] Circulating melanoma cells as a potential biomarker to detect metastasis and evaluate prognosis.2016

    • Author(s)
      Hida T, Yoneta A, Wakamatsu K, Yanagisawa K, Ishii-Osai Y, Kan Y, Kato J, Yamashita T
    • Journal Title

      Australas J Dermatol.

      Volume: Mar Issue: 2 Pages: 145-149

    • DOI

      10.1111/ajd.12455

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-15K09794
  • [Journal Article] Biochemical effects of the flavanol-rich lychee fruit extract on the melanin biosynthesis and reactive oxygen species.2016

    • Author(s)
      Hagiwara K, Okura M, Sumikawa Y, Hida T, Kuno A, Horio Y, Yamashita T.
    • Journal Title

      J Dermatol.

      Volume: 未定 Issue: 10 Pages: 1174-1183

    • DOI

      10.1111/1346-8138.13326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08312, KAKENHI-PROJECT-25461705
  • [Journal Article] Diagnosis of eight groups of xeroderma pigmentosum by genetic complementation using recombinant adenovirus vectors.2016

    • Author(s)
      Yamashita T, Okura M, Ishii-Osai Y, Hida T
    • Journal Title

      J Dermatol.

      Volume: Mar Issue: 10 Pages: 1167-1173

    • DOI

      10.1111/1346-8138.13333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461705
  • [Journal Article] Nagashima-type palmoplantar keratosis caused by compound heterozygous mutations in SERPINB7.2015

    • Author(s)
      Hida T, Okura M, Kamiya T, Yamashita T
    • Journal Title

      Eur J Dermatol.

      Volume: 25(2) Issue: 2 Pages: 202-203

    • DOI

      10.1684/ejd.2014.2515

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461705
  • [Journal Article] Nagashima-type palmoplantar keratosis caused by compound heterozygous mutations in SERPINB7.2015

    • Author(s)
      Hida T, Okura M, Kamiya T, Yamashita T.
    • Journal Title

      Eur J Dermatol 2015 mar [Epub ahead of print].

      Volume: 25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461705
  • [Journal Article] Ankyloblepharon-ectodermal defects-cleft lip/palate syndrome : a case with a novel p63 mutation associated with abnormal keratohyalin granules2014

    • Author(s)
      Hida T, Kase K, Hamada T, Matsuda M, Hashimoto T, Yamashita T.
    • Journal Title

      Eur J Dermatol

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770233
  • [Journal Article] Development of sarcoidosis during β-interferon therapy for melanoma.2014

    • Author(s)
      Shiki M, Hida T, Yamashita T
    • Journal Title

      J Dermatol

      Volume: 41(9) Issue: 9 Pages: 862-863

    • DOI

      10.1111/1346-8138.12581

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461705
  • [Journal Article] Ankyloblepharon-ectodermal defects-cleft lip/palate syndrome: a case with a novel p63 mutation associated with abnormal keratohyalin granules.2014

    • Author(s)
      Hida T, Kase K, Hamada T, Matsuda M, Hashimoto T, Yamashita T
    • Journal Title

      Eur J Dermatol

      Volume: 24(4) Issue: 4 Pages: 495-497

    • DOI

      10.1684/ejd.2014.2372

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461705
  • [Journal Article] Analysis of DNA methylation in bowel lavage fluid for detection of colorectal cancer.2014

    • Author(s)
      Harada T, Yamamoto E, Yamano HO, Nojima M, Maruyama R, Kumegawa K, Ashida M, Yoshikawa K, Kimura T, Harada E, Takagi R, Tanaka Y, Aoki H, Nishizono M, Nakaoka M, Tuyada A, Niinuma T, Kai M, Shimoda K, Shinomura Y, Sugai T, Imai K, Suzuki H.
    • Journal Title

      Cancer Prev Res (Phila)

      Volume: 7(10) Issue: 10 Pages: 1002-1010

    • DOI

      10.1158/1940-6207.capr-14-0162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] A case of oculocutaneous albinism type 4: aberrant expression of SLC45A2 transcript with exon skipping.2014

    • Author(s)
      Hida T, Okura M, Tanaka T, Yamashita T
    • Journal Title

      J Dermatol

      Volume: 41(11) Issue: 11 Pages: 1019-1021

    • DOI

      10.1111/1346-8138.12652

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461705
  • [Journal Article] 皮膚悪性腫瘍-基礎と臨床の最新研究動向- 悪性黒色腫の分子生物学 p53経路: ARD2013

    • Author(s)
      山下利春, 肥田時征
    • Journal Title

      日本臨床

      Volume: 71 Pages: 154-156

    • Data Source
      KAKENHI-PROJECT-25461705
  • [Journal Article] Pigmented mammary Paget’s disease presenting with dermoscopic features of multiple dots.2013

    • Author(s)
      Hida T, Yamashita T
    • Journal Title

      Australas J Dermatol

      Volume: in print Issue: 4 Pages: 260-262

    • DOI

      10.1111/ajd.12086

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770233, KAKENHI-PROJECT-25461705
  • [Journal Article] Influence of isoflavone intake and equol-producing intestinal flora on prostate cancer risk2013

    • Author(s)
      Sugiyama Y, Masumori N, Fukuta F, Yoneta A, Hida T, Yamashita T, Minatoya M, Nagata Y, Mori M, Tsuji H, Akaza H, Tsukamoto T
    • Journal Title

      Asian Pac J Cancer Prev

      Volume: 14 Issue: 1 Pages: 1-4

    • DOI

      10.7314/apjcp.2013.14.1.1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770233
  • [Journal Article] Influence of isoflavones intake and equolproducing intestinal flora on prostate cancer risk2013

    • Author(s)
      Sugiyama Y, Masumori N, Fukuta F, Yoneta A, Hida T, Yamashita T, Minatoya M, Nagata Y, Mori M, Tsuji H, Akaza H, Tsukamoto T
    • Journal Title

      Asia Pacific J Cancer Prev

      Volume: 14 Pages: 1-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461705
  • [Journal Article] 悪性黒色皮膚悪性腫瘍-基礎と臨床の最新研究動向- 悪性黒色腫の検査・治療 腫瘍マーカー2013

    • Author(s)
      肥田時征, 山下利春
    • Journal Title

      日本臨床

      Volume: 71 Pages: 270-273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461705
  • [Journal Article] Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk2013

    • Author(s)
      Suzuki R, Nosho K (他14名), Yamamoto H, Shinomura Y
    • Journal Title

      J Gastroenterol

      Volume: (Epub ahead of print) Issue: 7 Pages: 1135-1144

    • DOI

      10.1007/s00535-013-0861-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23791283, KAKENHI-PROJECT-25460420, KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-25670371, KAKENHI-PROJECT-25830103, KAKENHI-PROJECT-25860547, KAKENHI-PROJECT-25860548
  • [Journal Article] Pigmented Mammary Paget's Disease Mimicking Melanoma : Report of Three Cases2012

    • Author(s)
      Hida T, Yamashita T, et al.
    • Journal Title

      Eur J Dermatol

      Volume: 22 Pages: 121-124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591228
  • [Journal Article] Pigmented mammary Paget’s disease mimicking melanoma: report of three cases.2012

    • Author(s)
      Hida T
    • Journal Title

      Eur J Dermatol

      Volume: 22 Pages: 121-124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591228
  • [Journal Article] Pigmented Mammary Paget's Disease Mimicking Melanoma : Report of Three Cases2012

    • Author(s)
      Hida T, Yamashita T, et al
    • Journal Title

      Eur J Dermatol

      Volume: 22(1) Pages: 121-124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591228
  • [Journal Article] Etanercept-induced lichen planus-like eruptions following the lines of Blaschko2012

    • Author(s)
      Utsu M, Hida T, Takahashi H, Yamashita T
    • Journal Title

      Eur J Dermatol

      Volume: 22 Issue: 4 Pages: 544-545

    • DOI

      10.1684/ejd.2012.1747

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770233
  • [Journal Article] Pigmented mammary Paget's disease mimicking melanoma : report of three cases2012

    • Author(s)
      Hida T, Yoneta A, Nishizaka T, Ohmura T, Suzuki Y, Kameshima H, Yamashita T
    • Journal Title

      Eur J Dermatol

      Volume: 22 Issue: 1 Pages: 121-124

    • DOI

      10.1684/ejd.2011.1580

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770233
  • [Journal Article] Rab7 is a critical mediator in vesicular transport of tyrosinase-related protein 1 in melanocytes2011

    • Author(s)
      Hida T
    • Journal Title

      J Dermatol

      Volume: 38 Issue: 5 Pages: 432-441

    • DOI

      10.1111/j.1346-8138.2010.01004.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591489, KAKENHI-PROJECT-22591228
  • [Journal Article] Cytokeratin expression patterns in multiple infundibulocystic basal cell carcinoma.2011

    • Author(s)
      Hida T, Saga K, Kimura T
    • Journal Title

      J Cutan Pathol 38

      Pages: 309-313

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790808
  • [Journal Article] Rab7 is a critical mediator in vesicular transport of tyrosinase-related protein 1 in melanocytes.2011

    • Author(s)
      Hida T, Sohma H, Kokai Y, Kawakami A, Hirosaki K, Okura M, Tosa N, Yamashita T, Jimbow K
    • Journal Title

      J Dermatol 38

      Pages: 432-441

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790808
  • [Journal Article] Rab7 is a critical mediator in vesicular transport of tyrosinase-related protein 1 in melanocytes2011

    • Author(s)
      Hida T, Sohma H, Kokai Y, Kawakami A, Hirosaki K, Okura M, Tosa N, Yamashita T, Jimbow K
    • Journal Title

      J Dermatol 38

      Pages: 432-441

    • Data Source
      KAKENHI-PROJECT-22591228
  • [Journal Article] Rab7 is a critical mediator in vesicular transport of tyrosinase-relatoteinl in melanocytes.2010

    • Author(s)
      Hida T, Yamashita T, et al.
    • Journal Title

      J Dermatol

      Volume: 37 Pages: 1-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591228
  • [Journal Article] Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes : a cAMP-independent pathway.2009

    • Author(s)
      Hida T, Wakamatsu K, Sviderskaya EV, Donkin AJ, Montoliu L, Lynn Lamoreux M, Yu B, Millhauser GL, Ito S, Barsh GS, Jimbow K, Bennett DC
    • Journal Title

      Pigment Cell Melanoma Res 22

      Pages: 623-634

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790808
  • [Journal Article] Spontaneous regression of bowenoid papulosis in a patient with acquired immunodeficiency syndrome after an increase in peripheral CD4+ T lymphocytes.2009

    • Author(s)
      Kawakami A, Saga K, Ono I, Hida T, Jimbow K, Yamashita T
    • Journal Title

      Int J Dermatol 48

      Pages: 210-212

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790808
  • [Journal Article] Macrophage inhibitory cytokine-1 : a new player in melanoma development.2009

    • Author(s)
      Yamashita T, Yoneta A, Hida T
    • Journal Title

      J Invest Dermatol 129(2)

      Pages: 262-264

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790808
  • [Presentation] メラノーマの遺伝子異常2021

    • Author(s)
      肥田時征
    • Organizer
      第30回日本色素細胞学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K08304
  • [Presentation] メラノーマに特化したシーケンスパネルの開発2021

    • Author(s)
      肥田時征
    • Organizer
      第425回日本皮膚科学会北海道地方会
    • Data Source
      KAKENHI-PROJECT-21K08304
  • [Presentation] カスタムパネルシーケンスを用いた日本人メラノーマのドライバー遺伝子の検出2021

    • Author(s)
      肥田時征
    • Organizer
      第120回日本皮膚科学会総会
    • Data Source
      KAKENHI-PROJECT-21K08304
  • [Presentation] Dermoscopic findings of pigmented mammary Paget's disease2013

    • Author(s)
      Hida T, Yoneta A, Yamashita T
    • Organizer
      The 9th Asian Dermatological Congress
    • Place of Presentation
      Hong Kong
    • Data Source
      KAKENHI-PROJECT-23770233
  • [Presentation] Dermoscopic findings of pigmented mammary paget’s Disease.2013

    • Author(s)
      Hida T, Yoneta A, Yamashita T.
    • Organizer
      9th Asian Dermatological Congress
    • Place of Presentation
      Hong Kong
    • Data Source
      KAKENHI-PROJECT-23770233
  • [Presentation] 眼皮膚白皮症4型の一例2013

    • Author(s)
      肥田時征, 黄倉真恵, 山下利春
    • Organizer
      第25回日本色素細胞学会学術大会
    • Place of Presentation
      大阪, 日本
    • Data Source
      KAKENHI-PROJECT-25461705
  • [Presentation] AEC症候群の1例2013

    • Author(s)
      肥田時征,加瀬貴美,濱田尚宏,松田光弘,橋本隆,浅沼秀臣,山下利春
    • Organizer
      第395回日本皮膚科学会北海道地方会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23770233
  • [Presentation] 眼皮膚白皮症4型の一例2013

    • Author(s)
      肥田時征,黄倉真恵,山下利春
    • Organizer
      第25回日本色素細胞学会学術大会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23770233
  • [Presentation] Ankyloblepharon-ectodermal defects-cleft lip/palate syndrome2013

    • Author(s)
      肥田時征,加瀬貴美,濱田尚宏,松田光弘,橋本隆,浅沼秀臣,重富浩子,山下利春
    • Organizer
      日本人類遺伝学会第58回大会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23770233
  • [Presentation] 原因物質により多彩な臨床像を示す異物肉芽腫~診断の第一歩として問診が重要な肉芽腫~2013

    • Author(s)
      肥田時征
    • Organizer
      第112回日本皮膚科学会総会教育講演
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23770233
  • [Presentation] インドシアニングリーン蛍光法を併用した悪性黒色腫センチネルリンパ節生検2012

    • Author(s)
      肥田時征,筬井泰江,小野一郎,山下利春
    • Organizer
      第111回日本皮膚科学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23770233
  • [Presentation] Diagnosis of xeroderma pigmentosum by recombinant adenovirus infection and measurement of UV sensitivity of patient fibroblasts2012

    • Author(s)
      Okura M, Osai Y, Hida T, Mori S, Yamashita T
    • Organizer
      The 2nd Eastern Asia Dermatology Congress
    • Place of Presentation
      Beijing, China
    • Data Source
      KAKENHI-PROJECT-23770233
  • [Presentation] Effects of a low-molecular-weight polyphenol (oligonol) on the growth and melanogenesis of primary melanocytes and melanoma cells2011

    • Author(s)
      Okura M, Hagiwara K, Hida T, Yoneta A, Yanagisawa K, Horio Y, Yamashita T
    • Organizer
      The 19th International Pigment Cell Conference
    • Place of Presentation
      Bordeaux, France
    • Data Source
      KAKENHI-PROJECT-23770233
  • [Presentation] Two cases of advanced melanoma treated with dendritic cell vaccination therapy2011

    • Author(s)
      Yoneta A, Nishizaka T, Hida T, Goto S, Ozawa M, Yamashita T
    • Organizer
      The 22nd World Congress of Dermatology
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-23770233
  • [Presentation] Efficacy and safety of 5% imiquimod cream for the treatment of skin cancers.2010

    • Author(s)
      Yoneta A, Endo M, Mori S, Yanagisawa K, Hida T, Yamashita T
    • Organizer
      The first eastern Asia Dermatology Congress
    • Place of Presentation
      Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-20790808
  • [Presentation] Detection of circulating melanoma cells (CMCs) in melanoma patients.

    • Author(s)
      Hida T, Wakamatsu K, Yamashita T
    • Organizer
      XXII Intenational Pigment Cell Conference.
    • Place of Presentation
      Singapore
    • Year and Date
      2014-09-04 – 2014-09-07
    • Data Source
      KAKENHI-PROJECT-25461705
  • 1.  YAMASITA Tosiharu (50167706)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 16 results
  • 2.  井戸川 雅史 (00404749)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  HORIO Yosiyuki (30181530)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  鈴木 拓 (20381254)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  宇原 久 (40201355)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  NOSHO Katsuhiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  山本 博幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  篠村 恭久
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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