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Hoshino Hitomi  星野 瞳

ORCIDConnect your ORCID iD *help
… Alternative Names

星野 瞳  ホシノ ヒトミ

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Researcher Number 90500710
Other IDs
Affiliation (Current) 2025: 福井大学, 学術研究院医学系部門, 助教
Affiliation (based on the past Project Information) *help 2022 – 2023: 福井大学, 学術研究院医学系部門, 助教
2019: 福井大学, 学術研究院医学系部門, 助教
2016 – 2018: 福井大学, 学術研究院医学系部門, 特命助教
2015: 福井大学, 医学部, 特命助教
2011: 国立長寿医療研究センター, アルツハイマー病研究部, 流動研究員
Review Section/Research Field
Principal Investigator
Human pathology / Basic Section 49020:Human pathology-related / Experimental pathology
Keywords
Principal Investigator
糖鎖 / 細胆管反応 / 肝臓 / 肝内胆管 / 糖タンパク質 / 免疫沈降 / ウェスタンブロット / 遺伝子発現ベクター / ムチン / MUC6 … More / 硫酸化糖鎖 / 細胞傷害 / 再生 / 肝傷害 / EMA / MUC1 / 細胆管細胞癌 / セレクチン / 脳 / アルツハイマー病 Less
  • Research Projects

    (4 results)
  • Research Products

    (36 results)
  • Co-Researchers

    (3 People)
  •  硫酸化糖鎖に着目した胆管細胞におけるムチンコアタンパク質の機能解析Principal Investigator

    • Principal Investigator
      星野 瞳
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      University of Fukui
  •  Functional analysis of sulfated glycans in ductular reactionsPrincipal Investigator

    • Principal Investigator
      Hoshino Hitomi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Fukui
  •  Characterization of the glycosylation pattern in cholangiolocellular carcinomaPrincipal Investigator

    • Principal Investigator
      Hoshino Hitomi
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      University of Fukui
  •  ヒトアルツハイマー病剖検脳におけるセレクチン-糖鎖発現解析Principal Investigator

    • Principal Investigator
      星野 瞳
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      National Center for Geriatrics and Gerontology

All 2024 2023 2022 2019 2018 2017 2016 2015 2011

All Journal Article Presentation

  • [Journal Article] Expression of low-sulfated keratan sulfate in non-mucinous ovarian carcinoma2024

    • Author(s)
      Hoshino H, Chen YY, Inoue D, Yoshida Y, Khoo KH, Akama TO, Kobayashi M
    • Journal Title

      Glycobiology

      Volume: 34 Issue: 1

    • DOI

      10.1093/glycob/cwad056

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06977, KAKENHI-PROJECT-21H02702
  • [Journal Article] Paradoxical expression of R-10G-reactive antigen in human testicular embryonal carcinoma2023

    • Author(s)
      Muramoto A, Inamura S, Hoshino H, Terada N, Kobayashi M
    • Journal Title

      J Histochem Cytochem

      Volume: 71 Issue: 10 Pages: 555-563

    • DOI

      10.1369/00221554231199134

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K06977, KAKENHI-PROJECT-21H02702
  • [Journal Article] Distinct sulfated glycans expressed in intrahepatic cholangiocarcinoma: a potential target for new therapy2023

    • Author(s)
      Hoshino H, Kobayashi M
    • Journal Title

      Immunotherapy

      Volume: 15 Issue: 7 Pages: 503-516

    • DOI

      10.2217/imt-2022-0220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H02702, KAKENHI-PROJECT-22K06977
  • [Journal Article] Sulfated Glycans Recognized by S1 Monoclonal Antibody can Serve as a Diagnostic Marker for Malignant Pleural Mesothelioma2022

    • Author(s)
      Koki Nakashima, Yasuhiro Sakai, Hitomi Hoshino, Yukihiro Umeda, Hiroto Kawashima, Yoshitaka Sekido, Tamotsu Ishizuka, Motohiro Kobayashi
    • Journal Title

      Lung

      Volume: 200 Issue: 3 Pages: 531-534

    • DOI

      10.1007/s00408-022-00531-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K06977, KAKENHI-PROJECT-20H03379, KAKENHI-PROJECT-21H02702, KAKENHI-PROJECT-20K16228
  • [Journal Article] Expression and Clinical Significance of Spi-B in B-cell Acute Lymphoblastic Leukemia2022

    • Author(s)
      Yuzuru Ariga, Shulin Low, Hitomi Hoshino, Tsutomu Nakada, Tomoya O Akama, Akifumi Muramoto, Mana Fukushima, Takahiro Yamauchi, Yusei Ohshima, Motohiro Kobayashi
    • Journal Title

      J Histochem Cytochem

      Volume: 70 Issue: 10 Pages: 683-694

    • DOI

      10.1369/00221554221130383

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K06977, KAKENHI-PROJECT-21H02702, KAKENHI-PROJECT-20K16173
  • [Journal Article] Induction of peripheral lymph node addressin in human nasal mucosa with eosinophilic chronic rhinosinusitis.2019

    • Author(s)
      Tsutsumiuchi T, Hoshino H, Fujiieda S, Kobayashi M.
    • Journal Title

      Pathology

      Volume: 51 Issue: 3 Pages: 268-273

    • DOI

      10.1016/j.pathol.2019.01.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08758
  • [Journal Article] Low-dose Docetaxel Enhanced the Anticancer Effect of Temsirolimus by Overcoming Autophagy in Prostate Cancer Cells.2019

    • Author(s)
      Inamura SO, Ito H, Taga M, Tsuchiyama K, Hoshino H, Kobayashi M, Yokoyama O.
    • Journal Title

      Anticancer Res

      Volume: 10 Issue: 10 Pages: 5417-5425

    • DOI

      10.21873/anticanres.13735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08758
  • [Journal Article] Preferential expression of sialyl 6'-sulfo N-acetyllactosamine-capped O-glycans on high endothelial venules in human peripheral lymph nodes.2019

    • Author(s)
      Tsutsumiuchi M, Hoshino H, Kogami A, Tsutsumiuchi T1, Yokoyama O, Akama TO, Kobayashi M.
    • Journal Title

      Lab Invest

      Volume: 99 Issue: 10 Pages: 1428-1441

    • DOI

      10.1038/s41374-019-0267-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08758
  • [Journal Article] Role of MAdCAM-1-expressing high endothelial venule-like vessels in colitis induced in mice lacking sulfotransferases catalyzing L-selectin ligand biosynthesis.2018

    • Author(s)
      Low S, Hirakawa J, Hoshino H, Uchimura K, Kawashim H, Kobayashi M
    • Journal Title

      J Histochem Cytochem

      Volume: 1:22155417753363 Issue: 6 Pages: 415-425

    • DOI

      10.1369/0022155417753363

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08758, KAKENHI-PROJECT-17K19542, KAKENHI-PROJECT-16H05086, KAKENHI-PROJECT-15K08343, KAKENHI-PROJECT-15K14955, KAKENHI-PROJECT-15K18869
  • [Journal Article] Role of sialyl 6-sulfo Lewis X in antitumor immunity against oral squamous cell carcinoma.2017

    • Author(s)
      Yoshida H, Hoshino H, Imumura Y, Yoshimura H, Sano K, Kobayashi M
    • Journal Title

      J Oral Pathol Med

      Volume: 46 Issue: 9 Pages: 759-765

    • DOI

      10.1111/jop.12585

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08758, KAKENHI-PROJECT-15K08343
  • [Journal Article] Clinicopathological implications to micropapillary bladder urothelial carcinoma of the presence of sialyl Lewis X-decorated mucin 1 in stroma-facing membranes.2017

    • Author(s)
      Shinagawa T, Hoshino H, Taga M, Sakai Y, Imamura Y, Yokoyama O, Kobayashi M
    • Journal Title

      Urol Oncol

      Volume: 35 Issue: 10 Pages: 606.e17-606.e23

    • DOI

      10.1016/j.urolonc.2017.06.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08758, KAKENHI-PROJECT-15K08343
  • [Journal Article] Appearance of high endothelial venule-like vessels in benign prostatic hyperplasia is associated with lower urinary tract symptom2017

    • Author(s)
      Inamura S, Shinagawa T, Hoshino H, Sakai Y, Imamura Y, Yokoyama O, Kobayashi M
    • Journal Title

      Prostate

      Volume: 77 Issue: 7 Pages: 794-802

    • DOI

      10.1002/pros.23319

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K19049, KAKENHI-PROJECT-17K08758, KAKENHI-PROJECT-17H04326, KAKENHI-PROJECT-15K08343, KAKENHI-PROJECT-15K15582
  • [Journal Article] Apical membrane expression of distinct sulfated glycans represents a novel marker of cholangiolocellular carcinoma2016

    • Author(s)
      Hoshino H, Ohta M, Ito M, Uchimura K, Sakai Y, Uehara T, Low S, Fukushima M, Kobayashi M
    • Journal Title

      Lab Invest

      Volume: 96 Issue: 12 Pages: 1246-1255

    • DOI

      10.1038/labinvest.2016.104

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K19049, KAKENHI-PROJECT-15K08343
  • [Journal Article] High endothelial venule-like vessels and lymphocyte recruitment in diffuse sclerosing variant of papillary thyroid carcinoma.2016

    • Author(s)
      Shulin L, Sakai Y., Hoshino H, Hirokawa M, Kawashima H, Higuchi K, Imamura Y, Kobayashi M
    • Journal Title

      Pathology

      Volume: 48 Issue: 7 Pages: 666-674

    • DOI

      10.1016/j.pathol.2016.08.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05086, KAKENHI-PROJECT-15K19049, KAKENHI-PROJECT-15K08343, KAKENHI-PROJECT-15K14955
  • [Journal Article] A potential role for 6-sulfo sialyl Lewis X in metastasis of bladder urothelial carcinoma2015

    • Author(s)
      Taga M, Hoshino H, Low S, Imamura Y, Ito H, Yokoyama O, Kobayashi M
    • Journal Title

      Urol Oncol

      Volume: 33 Issue: 11 Pages: 496.e1-496.e9

    • DOI

      10.1016/j.urolonc.2015.05.026

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K08343, KAKENHI-PROJECT-15K19049
  • [Presentation] Establishment of a clear cell ovarian carcinoma cell line expressing low-sulfated keratan sulfate2024

    • Author(s)
      Hoshino H, Inoue D, Yoshida H, Shigeto S, Kazuyuki M, Akama O T, Yoshida Y, Kobayashi M
    • Organizer
      第113回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-22K06977
  • [Presentation] Distinct sulfated glycans expressed in intrahepatic cholangiocarcinoma2023

    • Author(s)
      Hoshino H, Fukushim M, Muramoto A, Kobayashi M
    • Organizer
      第112回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-22K06977
  • [Presentation] Expression of low-sulfated keratan sulfate in non-mucinous ovarian carcinoma2023

    • Author(s)
      Hoshino H, Chen Ya-Y, Inoue D, Yoshida Y, Khoo Kay-H, Kobayashi M
    • Organizer
      26th International symposium on Glycoconjugates
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06977
  • [Presentation] Establishment of human ovarian cancer-derived cell lines2022

    • Author(s)
      Hitomi Hoshino, Daisuke Inoue, Tomoya O Akama, Motohiro Kobayashi
    • Organizer
      第68回日本病理学会秋期特別総会
    • Data Source
      KAKENHI-PROJECT-22K06977
  • [Presentation] Expression of sialyl 6’-sulfo N-acetyllactosamine -capped O-glycans on high endothelial venules2019

    • Author(s)
      Tsutsumiuchi M, Hoshino H, Kogami A, Tsutsumiuchi T, Yokoyama O, Akama O T, Kobayashi M
    • Organizer
      第108回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K08758
  • [Presentation] Induction of peripheral lymph node addressin in human nasal mucosa with eosinophilic chronic rhinosinusitis.2019

    • Author(s)
      Tsutsumiuchi T, Hoshino H, Fujieda S, Kobayashi M.
    • Organizer
      29th Annual conference of the society for Glycobiology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08758
  • [Presentation] Role of sialyl 6-sulfo Lewis X in anti-tumor immunity against oral squamous cell carcinoma.2018

    • Author(s)
      Hoshino H, Yoshida H, Imamura Y, Yoshimura H, Sano K, Kobayashi M.
    • Organizer
      28th Annual conference of the society for Glycobiology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08758
  • [Presentation] Role of sialyl 6-sulfo Lewis X in antitumor immunity against oral squamous cell carcinoma.2018

    • Author(s)
      Yoshida H, ○Hoshino H, Imumura Y, Yoshimura H, Sano K, Kobayashi M.
    • Organizer
      第107回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K08758
  • [Presentation] Apical membrane expression of distinct sulfated glycans is a novel marker of cholangiolocellular carcinoma.2018

    • Author(s)
      Hoshino H, Ohta M, Ito M, Uchimura K, Sakai Y, Uehara T, Low S, Fukushima M, Kobayashi M.
    • Organizer
      第36回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-17K08758
  • [Presentation] Apical membrane expression of sialyl 6-sulfo Lewis X glycans in cholangiolocellular carcinoma.2018

    • Author(s)
      Hoshino H, Kobayshi M.
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K08758
  • [Presentation] Clinicopathological implications to micropapillary bladder urothelial carcinoma of the presence of sialyl Lewis X-decorated mucin 1 in stroma-facing membranes.2017

    • Author(s)
      Shinagawa T, Hoshino H, Taga M, Sakai Y, Imamura Y, Yokoyama O, Kobayashi M.
    • Organizer
      27th Annual conference of the society for Glycobiology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08758
  • [Presentation] Apical membrane expression of distinct sulfated glycans is a novel marker of cholangiolocellular carcinoma.2017

    • Author(s)
      Hoshino H, Ohta M, Ito M, Uchimura K, Sakai Y, Uehara T, Low S, Fukushima M, Kobayashi M.
    • Organizer
      第36回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-17K08758
  • [Presentation] Apical membrane expression of distinct sulfated glycans represents a novel marker of cholangiolocellular carcinoma.2017

    • Author(s)
      Hoshino H, Ohta M, Ito M, Uchimura K, Sakai Y, Uehara T, Low S, Fukushima M, Kobayashi M
    • Organizer
      第106回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K08758
  • [Presentation] High endothelial venule-like vessels and lymphocyte recruitment in diffuse sclerosing variant of papillary thyroid carcinoma2017

    • Author(s)
      Low S, Kanamori R, Sakai Y, Hoshino H, Hirokawa M, Kawashima H, Higuchi K, Imamura Y, Kobayashi M
    • Organizer
      20th Annual San Diego Glycobiology Symposium
    • Place of Presentation
      San Diego, CA, USA
    • Year and Date
      2017-02-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19049
  • [Presentation] Apical membrane expression of distinct sulfated glycans represents a novel marker of cholangiolocellular carcinoma2017

    • Author(s)
      Hoshino H, Ohta M, Ito M, Uchimura K, Sakai Y, Uehara T, Low S, Fukushima M, Kobayashi M
    • Organizer
      20th Annual San Diego Glycobiology Symposium
    • Place of Presentation
      San Diego, CA, USA
    • Year and Date
      2017-02-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19049
  • [Presentation] 膀胱癌に発現する硫酸化シアリルルイスXに関する検討2016

    • Author(s)
      多賀 峰克, 伊藤 英明, 品川 友親, 堤内 真美, 星野 瞳, 小林 基弘, 横山 修
    • Organizer
      第104回日本泌尿器科学会総会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-04-23
    • Data Source
      KAKENHI-PROJECT-15K19049
  • [Presentation] Apical membrane expression of distinct sulfated glycans represents a novel marker of cholangiolocellular carcinoma2016

    • Author(s)
      Hoshino H, Ohta M, Ito M, Uchimura K, Sakai Y, Uehara T, Low S, Fukushima M, Kobayashi M
    • Organizer
      26th Annual conference of the society for Glycobiology
    • Place of Presentation
      New Orleans, LA, USA
    • Year and Date
      2016-11-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19049
  • [Presentation] A potential role for 6-sulfo sialyl Lewis X in metastasis of bladder urothelial carcinoma2016

    • Author(s)
      Taga M, Hoshino H, Los S, Imamura Y, Ito H, Kobayashi M, Yokoyama O
    • Organizer
      American Urology Association Annual Meeting
    • Place of Presentation
      San Diego, CA, USA
    • Year and Date
      2016-05-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19049
  • [Presentation] A potential role for 6-sulfo sialyl Lewis X in metastasis of bladder urothelial carcinoma2015

    • Author(s)
      Minekatsu Taga, Hitomi Hoshino, Shulin Low, and Motohiro Kobayashi
    • Organizer
      Annual conference of the society for Glycobiology
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2015-12-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19049
  • [Presentation] セレクチンリガンド形成に関わる硫酸転移酵素は生後マウス発達脳における5D4ケラタン硫酸糖鎖抗原の発現を制御する2011

    • Author(s)
      星野瞳
    • Organizer
      日本生化学会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-23790426
  • [Presentation] 生後マウス発達脳における5D4ケラタン硫酸の発現を制御する硫酸転移酵素およびフコース転移酵素について2011

    • Author(s)
      星野瞳
    • Organizer
      米国糖鎖生物学会
    • Place of Presentation
      シアトルウエスティン(米国シアトル)
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-23790426
  • 1.  KOBAYASHI Motohiro (00362137)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 33 results
  • 2.  内村 健治 (20450835)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 3.  川島 博人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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