Ushijima Hironori 牛島弘雅

… Alternative Names

HIRONORI Ushijima 牛島弘雅

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Researcher Number	90509043
Other IDs
Affiliation (Current)	2026: 国際医療福祉大学, 成田薬学部, 講師
Affiliation (based on the past Project Information) *help	2024 – 2025: 国際医療福祉大学, 成田薬学部, 講師 2019 – 2023: 岩手医科大学, 薬学部, 助教 2012 – 2013: 岩手医科大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Clinical oncology
Keywords	Principal Investigator 細胞老化 / 抗酸化活性 / necrostatin / RNA-seq / フレイル / パーシャルリプログラミング / アンチエイジング / 細胞増殖 / RNAシーケンシング / ラジカル除去活性 … More / necroptosis / マイクロRNA / Anisomycin / アニソマイシン / cAMP / cancer / JNK / PKA / 大腸癌 / 転写因子 / GATA-6 Less

Research Projects
(4 results)
Research Products
(18 results)

パーシャルリプログラミング誘導の強化による抗老化作用の評価Principal Investigator
- Principal Investigator
  
  牛島弘雅
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  International University of Health and Welfare
Search for factors responsible for restoring cell proliferation from a state of agingPrincipal Investigator
- Principal Investigator
  
  Hironori Ushijima
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  International University of Health and Welfare
  Iwate Medical University
Fundamental research on the molecular mechanisms of cellular senescence induced by anisomycin treatmentPrincipal Investigator
- Principal Investigator
  
  Ushijima Hironori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Iwate Medical University
Analysis of proteolytic mechanisms of GATA-6 as novel molecular target of chemotherapy for colorectal cancerPrincipal Investigator
- Principal Investigator
  
  HIRONORI Ushijima
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Clinical oncology
- Research Institution
  Iwate Medical University

All 2024 2023 2021 2020 2019 2013 2012

All Journal Article Presentation

[Journal Article] An in vitro evaluation of the antioxidant activities of necroptosis and apoptosis inhibitors: the potential of necrostatin-1 and necrostatin-1i to have radical scavenging activities2023
- Author(s)
  Ushijima Hironori、Monzaki Rina
- Journal Title
  
  Pharmacological Reports
  
  Volume: 75 Issue: 2 Pages: 490-497
- DOI
  10.1007/s43440-023-00450-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K11858
[Journal Article] Suppressive Effects of Anisomycin on the Proliferation of B16 Mouse Melanoma Cells <i>In Vitro</i>2021
- Author(s)
  USHIJIMA HIRONORI、MONZAKI RINA、ONODERA ARISA
- Journal Title
  
  Anticancer Research
  
  Volume: 41 Issue: 12 Pages: 6113-6121
- DOI
  10.21873/anticanres.15431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11749
[Journal Article] Analysis of differentially expressed genes responsible for the suppressive effect of anisomycin on cell proliferation of DLD-1?cells2021
- Author(s)
  Ushijima Hironori、Monzaki Rina、Funakoshi Mika
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 27 Pages: 101038-101038
- DOI
  10.1016/j.bbrep.2021.101038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11749
[Journal Article] c-AMP dependent proteplysis of GATA-6 is linked to JNK pathway2012
- Author(s)
  Hironori Ushijima, Masatomo Maeda
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 423 Issue: 4 Pages: 679-683
- DOI
  10.1016/j.bbrc.2012.06.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24701032
[Journal Article] Inhibitors of protein kinases affecting cAMP dependent proteiolysis of GATA-62012
- Author(s)
  Hironori Ushijima, Masatomo Maeda
- Journal Title
  
  Advances in Biological Chemistry
  
  Volume: 2 Issue: 04 Pages: 411-415
- DOI
  10.4236/abc.2012.24051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24701032
[Presentation] Investigating the potential antioxidant activities of Necrostatin-1 and Necrostatin-1i2024
- Author(s)
  Hironori Ushijima, Rina Monzaki
- Organizer
  Biomolecular Horizons 2024 Congress, Melbourne, Australia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11858
[Presentation] Analysis for expression pattern of cell senescence associated genes on DLD-1 cells treated with Anisomycin2020
- Author(s)
  Hionori Ushijima, Mika Funakoshi, Rina Monzaki
- Organizer
  ASCB/EMBO meeting, Cell Bio Virtual 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11749
[Presentation] Anisomycinによる大腸癌細胞の増殖抑制機構2019
- Author(s)
  牛島弘雅、舩越美佳
- Organizer
  日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-19K11749
[Presentation] ハイドロキノン及びトラネキサム酸によるメラニン産生減少機構2019
- Author(s)
  門崎莉奈、牛島弘雅
- Organizer
  日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-19K11749
[Presentation] Mechanism of anisomycin-induced nuclear export of GATA-62013
- Author(s)
  Hironori Ushijima, Kimika Endo, Masatomo Maeda
- Organizer
  FAOB Mini Symposium"Molecular Basis for Medical and Pharmaceutical Sciences"
- Place of Presentation
  Iwate, Japan
- Year and Date
  2013-04-06
- Data Source
  KAKENHI-PROJECT-24701032
[Presentation] JNK signaling promotes proteolysis of GATA-6 and suppresses growth of colorectal cancer cells2013
- Author(s)
  牛島弘雅、法霊崎明子、前田正知
- Organizer
  第86回日本生化学会
- Place of Presentation
  横浜
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PROJECT-24701032
[Presentation] 遺伝子破壊法によるGATA-6分解機構の解析2013
- Author(s)
  中目祐紀、荒木信、牛島弘雅、前田正知
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  東北大学
- Data Source
  KAKENHI-PROJECT-24701032
[Presentation] Mechanism of anisomycin-induced nuclear export of GATA-6.2013
- Author(s)
  Hironori Ushijima, Kimika Endo, Masatomo Maeda
- Organizer
  FAOB Mini Symposium “Molecular Basis for Medical and Pharmaceutical Sciences”
- Place of Presentation
  岩手医科大学
- Data Source
  KAKENHI-PROJECT-24701032
[Presentation] JNK signaling promotes proteolysis of GATA-6 and suppresses growth of colorectal cancer cells.2013
- Author(s)
  牛島弘雅、法霊崎明子、前田正知
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24701032
[Presentation] 遺伝子破壊法によるGATA-6分解機構の解析2013
- Author(s)
  中目祐紀、荒木信、牛島弘雅、前田正知
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Year and Date
  2013-10-20
- Data Source
  KAKENHI-PROJECT-24701032
[Presentation] Proteolytic mechanisms of GATA-6 facilitated by activation of JNK signaling pathway2012
- Author(s)
  Hironori Ushijima
- Organizer
  The 26th Annual Symposium of The Protein Society
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24701032
[Presentation] Proteolytic mechanisms of GATA-6 facilitated by activation of JNK signaling pathway2012
- Author(s)
  Hironori Ushijima, Kimika Endo, Yuki Nakanome, Masatomo Maeda
- Organizer
  The 26^<th> Annual Symposium of The Protein Society
- Place of Presentation
  San Diego, USA
- Year and Date
  2012-08-05
- Data Source
  KAKENHI-PROJECT-24701032
[Presentation] JNKシグナルを介したGATA-6分解機構の解析2012
- Author(s)
  遠藤希美加、牛島弘雅、前田正知
- Organizer
  第51回日本薬学会東北支部大会
- Place of Presentation
  青森
- Year and Date
  2012-10-12
- Data Source
  KAKENHI-PROJECT-24701032

Ushijima Hironori 牛島 弘雅

HIRONORI Ushijima 牛島 弘雅

Research Projects

Research Products

パーシャルリプログラミング誘導の強化による抗老化作用の評価Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Search for factors responsible for restoring cell proliferation from a state of agingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Fundamental research on the molecular mechanisms of cellular senescence induced by anisomycin treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of proteolytic mechanisms of GATA-6 as novel molecular target of chemotherapy for colorectal cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] An in vitro evaluation of the antioxidant activities of necroptosis and apoptosis inhibitors: the potential of necrostatin-1 and necrostatin-1i to have radical scavenging activities2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Suppressive Effects of Anisomycin on the Proliferation of B16 Mouse Melanoma Cells <i>In Vitro</i>2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of differentially expressed genes responsible for the suppressive effect of anisomycin on cell proliferation of DLD-1?cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] c-AMP dependent proteplysis of GATA-6 is linked to JNK pathway2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibitors of protein kinases affecting cAMP dependent proteiolysis of GATA-62012

Author(s)

Journal Title

DOI

Data Source

[Presentation] Investigating the potential antioxidant activities of Necrostatin-1 and Necrostatin-1i2024

Author(s)

Organizer

Data Source

[Presentation] Analysis for expression pattern of cell senescence associated genes on DLD-1 cells treated with Anisomycin2020

Author(s)

Organizer

Data Source

[Presentation] Anisomycinによる大腸癌細胞の増殖抑制機構2019

Author(s)

Organizer

Data Source

[Presentation] ハイドロキノン及びトラネキサム酸によるメラニン産生減少機構2019

Author(s)

Organizer

Data Source

[Presentation] Mechanism of anisomycin-induced nuclear export of GATA-62013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] JNK signaling promotes proteolysis of GATA-6 and suppresses growth of colorectal cancer cells2013

Author(s)

Organizer

Place of Presentation

Year and Date

Ushijima Hironori 牛島弘雅

HIRONORI Ushijima 牛島弘雅