YAMAZAKI TAIGA 山崎大賀

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Yamazaki Taiga 山崎大賀

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Researcher Number	90524231
Other IDs	https://orcid.org/0000-0003-4674-0883
Affiliation (Current)	2025: 北里大学, 北里大学メディカルセンター, 上級研究員
Affiliation (based on the past Project Information) *help	2019 – 2022: 北里大学, 北里大学メディカルセンター, 上級研究員 2014 – 2017: 北里大学, 北里大学メディカルセンター, 上級研究員 2013: 北里大学, 付置研究所, 研究員 2012: 北里大学, 北里大学メディカルセンター, 上級研究員
Review Section/Research Field	Principal Investigator Basic Section 38060:Applied molecular and cellular biology-related / Applied molecular and cellular biology / Carcinogenesis
Keywords	Principal Investigator DNAメチル化 / ペリセントロメア / セントロメア / エピゲノム編集 / 初期胚発生 / 生殖細胞 / エピジェネティクス / 染色体不安定性 / 癌

ペリセントロメアDNA低メチル化を基盤としたがん細胞クロマチン特性の理解Principal Investigator
- Principal Investigator
  
  山崎大賀
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  Kitasato University
Verification of germline development ensured by centromere DNA methylation.Principal Investigator
- Principal Investigator
  
  Yamazaki Taiga
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  Kitasato University
Establishment of method inducing DNA methylation by epigenome editing.Principal Investigator
- Principal Investigator
  
  YAMAZAKI Taiga
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Kitasato University
Analysis of genome instability and centric DNA hypomethylation in cancer cells.Principal Investigator
- Principal Investigator
  
  YAMAZAKI TAIGA
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Carcinogenesis
- Research Institution
  Kitasato University

All 2023 2022 2021 2020 2019 2018 2017 2016 2014 2012

All Journal Article Presentation

[Journal Article] Targeted DNA Methylation in Mouse Early Embryos2023
- Author(s)
  Taiga Yamazaki, Yu Hatano, Noritada Kobayashi & Kazuo Yamagata
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2577 Pages: 243-254
- DOI
  10.1007/978-1-0716-2724-2_17
- ISBN
  9781071627235, 9781071627242
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05956, KAKENHI-PLANNED-18H05528
[Journal Article] Toward the Development of Epigenome Editing-Based Therapeutics: Potentials and Challenges.2023
- Author(s)
  Ueda J, Yamazaki T, Funakoshi H.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 24 Issue: 5 Pages: 4778-4778
- DOI
  10.3390/ijms24054778
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19K05956
[Journal Article] Effects of Roxadustat on Erythropoietin Production in the Rat Body2022
- Author(s)
  Yasuoka Yukiko,Izumi Yuichiro,Fukuyama Takashi,Omiya Haruki,Pham Truyen D.,Inoue Hideki,Oshima Tomomi,Yamazaki Taiga,Uematsu Takayuki,Kobayashi Noritada,Shimada Yoshitaka,Nagaba Yasushi,Yamashita Tetsuro,Mukoyama Masashi,Sato Yuichi,Wall Susan M.,Sands Jeff M.,Takahashi Noriko,Kawahara Katsumasa,Nonoguchi Hiroshi
- Journal Title
  
  Molecules
  
  Volume: 27 Issue: 3 Pages: 1119-1119
- DOI
  10.3390/molecules27031119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05956, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-21K08280
[Journal Article] Effects of Angiotensin II on Erythropoietin Production in the Kidney and Liver2021
- Author(s)
  Yasuoka Yukiko、Izumi Yuichiro、Fukuyama Takashi、Inoue Hideki、Oshima Tomomi、Yamazaki Taiga、Uematsu Takayuki、Kobayashi Noritada、Shimada Yoshitaka、Nagaba Yasushi、Mukoyama Masashi、Sato Yuichi、Sands Jeff M、Kawahara Katsumasa、Nonoguchi Hiroshi
- Journal Title
  
  Molecules
  
  Volume: 26 Issue: 17 Pages: 5399-5399
- DOI
  10.3390/molecules26175399
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05956, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-21K08280
[Journal Article] Erythropoietin production by the kidney and the liver in response to severe hypoxia evaluated by Western blotting with deglycosylation2020
- Author(s)
  Yukiko Yasuoka, Takashi Fukuyama, Yuichiro Izumi, Yushi Nakayama, Hideki Inoue, Kengo Yanagita, Tomomi Oshima, Taiga Yamazaki, Takayuki Uematsu 2, Noritada Kobayashi 2, Yoshitaka Shimada 5, Yasushi Nagaba, Masashi Mukoyama, Tetsuro Yamashita, Yuichi Sato, Jeff M Sands, Katsumasa Kawahara, Hiroshi Nonoguchi
- Journal Title
  
  Physiol Rep.
  
  Volume: 12 Issue: 12
- DOI
  10.14814/phy2.14485
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05956, KAKENHI-PROJECT-19K08935, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-18K08247
[Journal Article] Editing DNA Methylation in Mammalian Embryos.2020
- Author(s)
  Yamazaki T, Hatano Y, Taniguchi R, Kobayashi N, Yamagata K.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 21 Issue: 2 Pages: 637-637
- DOI
  10.3390/ijms21020637
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05956, KAKENHI-PROJECT-18H02357
[Journal Article] Expression of KK-LC-1, a cancer/testis antigen, at non-tumour sites of the stomach carrying a tumour2018
- Author(s)
  Fukuyama Takashi、Futawatari Nobue、Yamamura Rui、Yamazaki Taiga、Ichiki Yoshinobu、Ema Akira、Ushiku Hideki、Nishi Yatsushi、Takahashi Yoshihito、Otsuka Toshikazu、Yamazaki Hitoshi、Koizumi Wasaburo、Yasumoto Kosei、Kobayashi Noritada
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 6131-6131
- DOI
  10.1038/s41598-018-24514-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14924, KAKENHI-PROJECT-17K16578
[Journal Article] Targeted DNA methylation in pericentromeres with genome editing-based artificial DNA methyltransferase2017
- Author(s)
  Yamazaki Taiga、Hatano Yu、Handa Tetsuya、Kato Sakiko、Hoida Kensuke、Yamamura Rui、Fukuyama Takashi、Uematsu Takayuki、Kobayashi Noritada、Kimura Hiroshi、Yamagata Kazuo
- Journal Title
  
  PLoS ONE
  
  Volume: 12 Issue: 5 Pages: 1-18
- DOI
  10.1371/journal.pone.0177764
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09585, KAKENHI-PROJECT-17K16578, KAKENHI-PROJECT-17K17719, KAKENHI-PLANNED-25116005, KAKENHI-PROJECT-15K14924
[Journal Article] Correlation Between Expression of the Cancer/Testis Antigen KK-LC-1 and Helicobacter pylori Infection in Gastric Cancer2017
- Author(s)
  FUKUYAMA TAKASHI、FUTAWATARI NOBUE、ICHIKI YOSHINOBU、SHIDA AKIKO、YAMAZAKI TAIGA、NISHI YATSUSHI、NONOGUCHI HIROSHI、TAKAHASHI YOSHIHITO、YAMAZAKI HITOSHI、KOBAYASHI NORITADA
- Journal Title
  
  In Vivo
  
  Volume: 31 Issue: 3 Pages: 403-407
- DOI
  10.21873/invivo.11073
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16578, KAKENHI-PROJECT-15K14924
[Journal Article] Reevaluation of erythropoietin production by the nephron2014
- Author(s)
  Nagai T, Yasuoka Y, Kawahara K, Nonoguchi H, et al.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 449 Issue: 3 Pages: 222-228
- DOI
  10.1016/j.bbrc.2014.09.089
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591244, KAKENHI-PROJECT-24700954, KAKENHI-PROJECT-24790222, KAKENHI-PROJECT-26461226, KAKENHI-PROJECT-26461233, KAKENHI-PROJECT-26860613, KAKENHI-PROJECT-26893202
[Journal Article] Expression of three isoforms of Na-K-2Cl cotransporter (NKCC2) in the kidney and regulation by dehydration..2014
- Author(s)
  Itoh K, Izumi Y, Kawahara K, Nonoguchi H, et al.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 453 Issue: 2 Pages: 356-361
- DOI
  10.1016/j.bbrc.2014.05.014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591244, KAKENHI-PROJECT-24700954, KAKENHI-PROJECT-24790222, KAKENHI-PROJECT-26461233, KAKENHI-PROJECT-26860613, KAKENHI-PROJECT-26893202
[Journal Article] Helicobacter pylori, a carcinogen, induces the expression of melanoma antigen -coding gene(Mage) - A 3 , a cancer/testis antigen2012
- Author(s)
  Fukuyama T. ,Yamazaki T . , Fujita T., Uematsu T., Ichiki Y., Kaneko H., Suzuki T . , Kobayashi N
- Journal Title
  
  Tumor Biology
  
  Volume: 33 Issue: 6 Pages: 1881-1887
- DOI
  10.1007/s13277-012-0448-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700510, KAKENHI-PROJECT-23790919, KAKENHI-PROJECT-24700954
[Presentation] マウスES細胞増殖におけるセントロメアDNAメチル化機能2019
- Author(s)
  山崎大賀, 谷口稜弥, 波多野裕, 小林憲忠, 山縣一夫
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K05956
[Presentation] ゲノム編集技術を応用したペリセントロメアへの人為的・配列特異的DNAメチル化誘導2017
- Author(s)
  山崎大賀、波多野　裕、半田哲也、加藤佐樹子、穂井田謙介、山村瑠衣、福山　隆、植松崇之、小林憲忠、木村　宏、山縣一夫
- Organizer
  第11回日本エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-15K14924
[Presentation] 細菌由来CpGメチル化酵素を利用したエピゲノム編集技術の開発2016
- Author(s)
  山崎大賀
- Organizer
  第1回日本遺伝子細胞治療学会若手研究セミナー
- Place of Presentation
  東京慈恵医科大学1号館講堂（東京都・港区）
- Data Source
  KAKENHI-PROJECT-15K14924
[Presentation] ゲノム編集技術を応用したペリセントロメアへの人為的・配列特異的DNAメチル化誘導2016
- Author(s)
  山崎大賀、山縣一夫、小林憲忠
- Organizer
  第1回日本ゲノム編集学会
- Place of Presentation
  広島国際会議場（広島県・広島市）
- Data Source
  KAKENHI-PROJECT-15K14924
[Presentation] Targeted DNA methylation in pericentromere with genome editing based artificial DNA methyltransferase.2016
- Author(s)
  Taiga Yamazaki, Kazuo Yamagata, Noritada Kobayashi
- Organizer
  International Symposium on Epigenome Dynamics and Regulation in Germ Cells
- Place of Presentation
  京都府・京都大学百周年時計記念館
- Year and Date
  2016-02-18
- Data Source
  KAKENHI-PROJECT-15K14924

1. YASUOKA Yukiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. FUKUYAMA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. IZUMI Yuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 野々口博史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 河原克雅

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 植松崇之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 山崎聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YAMAZAKI TAIGA 山崎 大賀

Yamazaki Taiga 山崎 大賀

Research Projects

Research Products

Co-Researchers

ペリセントロメアDNA低メチル化を基盤としたがん細胞クロマチン特性の理解Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Verification of germline development ensured by centromere DNA methylation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of method inducing DNA methylation by epigenome editing.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of genome instability and centric DNA hypomethylation in cancer cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Targeted DNA Methylation in Mouse Early Embryos2023

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Toward the Development of Epigenome Editing-Based Therapeutics: Potentials and Challenges.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of Roxadustat on Erythropoietin Production in the Rat Body2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of Angiotensin II on Erythropoietin Production in the Kidney and Liver2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Erythropoietin production by the kidney and the liver in response to severe hypoxia evaluated by Western blotting with deglycosylation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Editing DNA Methylation in Mammalian Embryos.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression of KK-LC-1, a cancer/testis antigen, at non-tumour sites of the stomach carrying a tumour2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Targeted DNA methylation in pericentromeres with genome editing-based artificial DNA methyltransferase2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Correlation Between Expression of the Cancer/Testis Antigen KK-LC-1 and Helicobacter pylori Infection in Gastric Cancer2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reevaluation of erythropoietin production by the nephron2014

Author(s)

Journal Title

DOI

Data Source

YAMAZAKI TAIGA 山崎大賀

Yamazaki Taiga 山崎大賀