UEDA Hironori 上田裕紀

Researcher Number	90543463
Affiliation (based on the past Project Information) *help	2016: 大阪大学, 医学系研究科, 招へい研究員 2016: 大阪大学, 医学系研究科, 特任准教授 2016: 大阪大学, 大学院医学系研究科, 特任准教授 2014 – 2016: 大阪大学, 医学(系)研究科(研究院), 招へい研究員 2015: 大阪大学, 医学(系)研究科(研究院), 特任准教授 … More 2013 – 2014: 大阪大学, 医学(系)研究科(研究院), 研究員 2013: 大阪大学, 医学研究科, 特任准教授 2012: 大阪大学, 医学(系)研究科(研究院), 准教授 2011: 大阪大学, 医学系研究科, 特任准教授(常勤) 2010: 大阪大学, 医学系研究科, 特任准教授 2010: Osaka University, 大学院・医学系研究科, 特任准教授(常勤) 2009: Osaka University, 医学系研究科, 特任准教授(常勤) Less
Review Section/Research Field	Principal Investigator General medical chemistry / Endocrinology Except Principal Investigator General medical chemistry / General internal medicine(including psychosomatic medicine) / General internal medicine (including Psychosomatic medicine)
Keywords	Principal Investigator 糖尿病 / Zac1 / 転写因子 / CD4陽性Tリンパ球 / 膵ベータ細胞 / インスリン / ZAC1 / conditional knockout / TNDM / CD4+ T cells … More / MIN6 / Plagl1 / 新生児一過性糖尿病 / ZACl / 原因遺伝子 / 発症機序 / NSYマウス / TGF-β1 / Tリンパ球 / 発症原因遺伝子 / 糖尿病の遺伝素因 … More Except Principal Investigator 遺伝子 / タウ / βアミロイド / 認知症 / アルツハイマー病 / 糖尿病 / DNAメチル化 / ヒストン / 始原生殖細胞 / ヘテロクロマチン / ヒストンメチル化 / エピジェネティック制御 / 生殖細胞 / 胎仔発生 / ノックアウトマウス / 神経変性 / 痴呆 / 神経原線維変化 / 老人斑 / インスリン・シグナル / 恒常性破綻 / タウ・リン酸化 / ベータ・アミロイド / 脳科学 / 病理学 / 分子生物学 / 神経科学 Less

Analysis of the mechanism of homeostatic maintenance against Alzheimer's disease and its failure due to diabetes
- Principal Investigator
  
  SATO Naoyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  National Center for Geriatrics and Gerontology
  Osaka University
Functional analyses of Zac1: a candidate gene for chromosome 6q24-related transient neonatal diabetes mellitusPrincipal Investigator
- Principal Investigator
  
  UEDA Hironori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
Investigating the role of an unknown gene in germ cell epigenetic reprogramming
- Principal Investigator
  
  TASHIRO Fumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
The roles of insulin signaling between diabetes and Alzheimer's disease
- Principal Investigator
  
  SATO Naoyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Osaka University
The study of susceptibility genes loci to diabetes mellitus.Principal Investigator
- Principal Investigator
  
  UEDA Hironori
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Endocrinology
- Research Institution
  Osaka University

All 2017 2015 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Differential regulation of amyloid precursor protein/presenilin 1 interaction during Ab40/42 production detected using fusion constructs2012
- Author(s)
  Sato N
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 11 Pages: e48551-e48551
- DOI
  10.1371/journal.pone.0048551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390222, KAKENHI-PROJECT-22591284, KAKENHI-PROJECT-23390187, KAKENHI-PROJECT-23590874, KAKENHI-PROJECT-24659349
[Journal Article] 1型糖尿病の発症機構-最新の知見-2011
- Author(s)
  上田裕紀
- Journal Title
  
  内分泌・糖尿病・代謝内科印刷中
- Data Source
  KAKENHI-PROJECT-21890129
[Journal Article] T細胞の制御からみた1型糖尿病の発症機構2009
- Author(s)
  上田裕紀
- Journal Title
  
  分子糖尿病学の進歩-基礎から臨床まで- 2009
  
  Pages: 66-73
- Data Source
  KAKENHI-PROJECT-21890129
[Journal Article] T細胞の制御からみた1型糖尿病の発症機構2009
- Author(s)
  上田裕紀
- Journal Title
  
  分子糖尿病学の進歩-基礎から臨床までー
  
  Pages: 66-73
- Data Source
  KAKENHI-PROJECT-21890129
[Presentation] 新生児糖尿病原因候補遺伝子ノックアウトMIN6膵β細胞株の樹立2017
- Author(s)
  上田裕紀、宮崎早月、田代　文、宮崎純一
- Organizer
  第31回日本糖尿病・肥満動物学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-26460366
[Presentation] Zac1遺伝子ノックアウトマウスＭＩＮ6ベータ細胞株の樹立とその解析2015
- Author(s)
  宮崎早月、上田裕紀、田代　文、宮崎純一
- Organizer
  日本糖尿病学会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26460367
[Presentation] Zac1遺伝子ノックアウトMIN6ベータ細胞株の樹立とその解析2015
- Author(s)
  宮崎　早月,　上田　裕紀,　田代　文,　宮崎　純一
- Organizer
  日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26460366
[Presentation] Diabetes increases tau phosphorylation in APP mice : evidence that Abeta is prerequisite, but insufficient to cause tau phosphorylation2013
- Author(s)
  N Sato, M Mori-Ueda, T Tanaka, S Takeda, K Uchio-Yamada, H Ueda, M Shinohara, S Murayama, M Takeda, H Rakugi, R Morishita
- Organizer
  The 11th International Conference on Alzheimer's & Parkinson's Diseases AD/PD 2013
- Place of Presentation
  Italy
- Year and Date
  2013-02-10
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Amyloid precursor protein/presenilin 1 interaction is differentially regulated during Abeta40/42 production : detection using fusion constructs2013
- Author(s)
  N Sato, M Okochi, M Shinohara, G Thinakaran, S Takeda, A Fukumori, M Shinohara-Noma, M Mori-Ueda, H Hamada, M Takeda, H Rakugi, R Morishita
- Organizer
  The 11th International Conference on Alzheimer's & Parkinson's Diseases AD/PD 2013
- Place of Presentation
  Italy
- Year and Date
  2013-02-09
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Possible involvements of Abeta, insulin signaling and tau phosphorylation in the pathological interaction between Alzheimer disease and diabetes2013
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  AAIC 2013 The Alzheimer's Association International Conference 2013
- Place of Presentation
  Boston
- Year and Date
  2013-07-14
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Amyloid Precursor Protein/Presenilin 1 Interaction is Differentially Regulated during Aβ40/42 Production : Detection Using Fusion Constructs2012
- Author(s)
  Naoyuki Sato, Masayasu Okochi, Mitsuru Shinohara, Gopal Thinakaran, Shuko Takeda, Akio Fukumori, Motoko Shinohara-Noma, Mari Mori-Ueda, Hizuki Hamada, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  The 17th Takeda Science Foundation Symposium on Bioscience
- Place of Presentation
  Osaka
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] The mechanism by which diabetes mellitus increase the risk of Alzheimer disease2012
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Neuroscience2012
- Place of Presentation
  Nagoya
- Year and Date
  2012-09-18
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Tau phosphorylation is increased by diabetes mellitus in APP transgenic mice2012
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  The 17th Takeda Science Foundation Symposium on Bioscience
- Place of Presentation
  Osaka
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] The mechanisms by which diabetes mellitus increases the risk of Alzheimer's disease2012
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Keystone Symposia, Aging and Diseases of Aging
- Place of Presentation
  Tokyo
- Year and Date
  2012-10-25
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Roles of beta-amyloid and insulin resistance in the interaction between diabetes mellitus and Alzheimer's disease2012
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Gordon Research Conferences, Neurobiology of Brain Disorders
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] 免疫シナプスの3Dイメージング～Tリンパ球の内側から見たI型糖尿病～2011
- Author(s)
  上田裕紀
- Organizer
  第4回神戸生活習慣病研究会
- Place of Presentation
  神戸
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-21890129
[Presentation] 免疫シナプスの3Dイメージング～Tリンパ球の内側から見た1型糖尿病～2011
- Author(s)
  上田裕紀
- Organizer
  神戸生活習慣病研究会
- Place of Presentation
  神戸ラッセホール(招待講演)
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-21890129
[Presentation] CHANGE IN PLASMA BETA-AMYLOID LEVEL AFTER GLUCOSE LOADING : A POSSIBLE BIOMARKER FOR ALZHEIMER DISEASE2011
- Author(s)
  Naoyuki Sato, Shuko Takeda, Mari Ueda, Hisahiro Yu, Atsushi Moriguchi, Kozue Uchio-Yamada, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  AAIC (Alzheimer Association International Conference) 2011
- Place of Presentation
  Paris, France
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] 自然発症2型糖尿病モデルNSYマウスを用いた多因子疾患の機能分割2010
- Author(s)
  上田裕紀
- Organizer
  第24回日本糖尿病・肥満動物学会年次学術集会
- Place of Presentation
  ホテルコスモスクエアー国際交流センター(大阪)
- Year and Date
  2010-01-22
- Data Source
  KAKENHI-PROJECT-21890129
[Presentation] 免疫シナプスの細胞内微細構造とその動態の解析～Tリンパ球の内側から見たI型糖尿病～2010
- Author(s)
  上田裕紀
- Organizer
  第56回未来医療セミナー
- Place of Presentation
  大阪
- Year and Date
  2010-09-28
- Data Source
  KAKENHI-PROJECT-21890129
[Presentation] 自然発症2型糖尿病モデルNSYマウスを用いた多因子疾患の機能分割2010
- Author(s)
  上田裕紀, ほか
- Organizer
  第24回日本糖尿病・肥満動物学会年次学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21890129
[Presentation] 免疫シナプスの細胞内微細構造とその動態の解析～Tリンパ球の内側から見た1型糖尿病～2010
- Author(s)
  上田裕紀
- Organizer
  未来医療セミナー
- Place of Presentation
  大阪大学大学院医学系研究科講義棟(招待講演)
- Year and Date
  2010-09-28
- Data Source
  KAKENHI-PROJECT-21890129
[Presentation] 炎症制御システム～免疫シナプス～の構造と動態2009
- Author(s)
  上田裕紀
- Organizer
  第4回生活習慣病と動脈硬化のUp to date
- Place of Presentation
  大阪
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-21890129
[Presentation] 免疫シナプス不全へのアプローチ2009
- Author(s)
  上田裕紀
- Organizer
  第10回KK21抗老化・高血圧研究会
- Place of Presentation
  ホテルグランビア大阪
- Year and Date
  2009-04-16
- Data Source
  KAKENHI-PROJECT-21890129
[Presentation] Induction of a Cell Cycle Regulator : Zac1 in T lymphocyte Cell-Lines.2009
- Author(s)
  上田裕紀
- Organizer
  The 49th annual meeting for the American Society for Cell Biology
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21890129
[Presentation] 炎症制御システム～免疫シナプス～の構造と動態2009
- Author(s)
  上田裕紀
- Organizer
  生活習慣病と動脈硬化のup to date
- Place of Presentation
  千里阪急ホテル(大阪)
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-21890129
[Presentation] Induction of a Cell Cycle Regulator : Zac1 in T lymphocyte cell-lines2009
- Author(s)
  上田裕紀
- Organizer
  アメリカ細胞生物学会
- Place of Presentation
  米国サンデエゴ
- Year and Date
  2009-12-08
- Data Source
  KAKENHI-PROJECT-21890129
[Presentation] 免疫シナプス不全へのアプローチ2009
- Author(s)
  上田裕紀
- Organizer
  第10回KK21抗老化・高血圧研究会
- Place of Presentation
  大阪
- Year and Date
  2009-04-16
- Data Source
  KAKENHI-PROJECT-21890129
[Presentation] 転写因子Zac1のTリンパ球内制御ネットワークの解析
- Author(s)
  上田裕紀、宮崎純一
- Organizer
  1型糖尿病研究会
- Place of Presentation
  姫路
- Year and Date
  2014-11-01 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26460366

1. HAYASHI Shinichiro (20396740)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. SATO Naoyuki (70372612)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
3. UCHIO Kozue (70373397)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. MURAYAMA Shigeo (50183653)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. 宮崎早月 (60452439)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. IKEUCHI Takeshi (20372469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TAKEYA Yasushi (70590339)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TASHIRO Fumi (40136213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 田中稔久 (10294068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TAKEYA Miyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MUKOUZONO Masahiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MATSUURA Takumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

UEDA Hironori 上田 裕紀

Research Projects

Research Products

Co-Researchers

Analysis of the mechanism of homeostatic maintenance against Alzheimer's disease and its failure due to diabetes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analyses of Zac1: a candidate gene for chromosome 6q24-related transient neonatal diabetes mellitusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigating the role of an unknown gene in germ cell epigenetic reprogramming

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The roles of insulin signaling between diabetes and Alzheimer's disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study of susceptibility genes loci to diabetes mellitus.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Differential regulation of amyloid precursor protein/presenilin 1 interaction during Ab40/42 production detected using fusion constructs2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 1型糖尿病の発症機構-最新の知見-2011

Author(s)

Journal Title

Data Source

[Journal Article] T細胞の制御からみた1型糖尿病の発症機構2009

Author(s)

Journal Title

Data Source

[Journal Article] T細胞の制御からみた1型糖尿病の発症機構2009

Author(s)

Journal Title

Data Source

[Presentation] 新生児糖尿病原因候補遺伝子ノックアウトMIN6膵β細胞株の樹立2017

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Zac1遺伝子ノックアウトマウスＭＩＮ6ベータ細胞株の樹立とその解析2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Zac1遺伝子ノックアウトMIN6ベータ細胞株の樹立とその解析2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Diabetes increases tau phosphorylation in APP mice : evidence that Abeta is prerequisite, but insufficient to cause tau phosphorylation2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Amyloid precursor protein/presenilin 1 interaction is differentially regulated during Abeta40/42 production : detection using fusion constructs2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

UEDA Hironori 上田裕紀