SEKIGUCHI HIROYUKI 関口裕之

… Alternative Names

Sekiguchi Hiroyuki 関口裕之

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Researcher Number	90547233
Affiliation (Current)	2025: 湘南医療大学, 臨床医学研究所, 研究員
Affiliation (based on the past Project Information) *help	2019 – 2023: 湘南医療大学, 臨床医学研究所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related Except Principal Investigator Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator 血管新生 / 細菌分子 / BafA / コラーゲン結合ドメイン / 骨形成促進 / コラーラ結合型成長因子 / 幹細胞 / 成長因子 / 硬化ゲル / デキストラン … More / ヒアルロン酸 / 間葉系幹細胞送達 / 骨欠損治療 / 局所硬化ゲル / ゲル剤 / 徐放 / 骨形成蛋白 … More Except Principal Investigator 成長因子 / 局所硬化ゲル / コラーゲンミメティックペプチド / 環状コラーゲンミメティックペプチド / コラーゲン結合型成長因子 / コラーゲン結合成長因子模倣ペプチド / スフェロイド / 局所送達 / 運動器再生 / 環状コラーゲン結合ペプチド / オルガノイド / 細胞 / 多孔質材料 / 人工骨 / 脊椎固定 / 骨形成蛋白 / 間葉系幹細胞 / スフェロイド培養 / 多孔質剤材料 / 成長因子導入 / 骨癒合促進 / 脊椎固定術 Less

細菌由来血管新生因子を応用した新規血管新生促進因子の創生と骨再生への応用Principal Investigator
- Principal Investigator
  
  関口裕之
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  湘南医療大学
Development of Musculoskeletal Regeneration Techniques through the Construction of a Platform for Functional Organoid Fabrication and Local Delivery
- Principal Investigator
  
  Uchida Kentaro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kitasato University
Effect of growth factor/In Situ-Formed Hydrogel / Artificial bone Composites on Bone Formation
- Principal Investigator
  
  Saito Wataru
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kitasato University
Cell and Growth factor deliverly using in situ formed hydrogel for treatment of bone defectPrincipal Investigator
- Principal Investigator
  
  Sekiguchi Hiroyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  湘南医療大学

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] In situ-formed hyaluronan gel/BMP-2/hydroxyapatite composite promotes bone union in refractory fracture model mice2023
- Author(s)
  Saito H, Shoji S, Kuroda A, Inoue G, Tazawa R, Sekiguchi H, Fukushima K, Miyagi M, Takaso M, Uchida K
- Journal Title
  
  Biomed Mater Eng
  
  Volume: 34 Issue: 6 Pages: 537-544
- DOI
  10.3233/bme-230021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H03059
[Journal Article] Effect of spheroid size on gene expression profiles of a mouse mesenchymal stem cell line in spheroid culture2023
- Author(s)
  Kuroda A, Mineo A, Shoji S, Inoue G, Saito W, Sekiguchi H, Takaso M, Uchida K
- Journal Title
  
  Biomed Mater Eng
  
  Volume: 34 Issue: 1 Pages: 67-76
- DOI
  10.3233/bme-221406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09440
[Journal Article] Effect of Bone Morphogenetic Protein-2 (BMP-2)/Hydroxyapatite/In Situ-Formed Hyaluronan Hydrogel Composites on Bone Formation in a Murine Model of Posterolateral Lumbar Fusion2022
- Author(s)
  Kuroda A, Saito W, Inoue G, Miyagi M, Shoji S, Sekiguchi H, Takaso M, Uchida K
- Journal Title
  
  Cureus
  
  Volume: 14
- DOI
  10.7759/cureus.25509
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09440
[Journal Article] Expression of nerve growth factor in the callus during fracture healing in a fracture model in aged mice2022
- Author(s)
  Sekiguchi H, Inoue G, Shoji S, Tazawa R, Kuroda A, Miyagi M, Takaso M, Uchida K
- Journal Title
  
  Biomed Mater Eng
  
  Volume: 33 Issue: 2 Pages: 131-137
- DOI
  10.3233/bme-211284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18546, KAKENHI-PROJECT-20K23008
[Journal Article] Acceleration of bone formation using in situ-formed hyaluronan-hydrogel containing bone morphogenetic protein-2 in a mouse critical size bone defect model2021
- Author(s)
  Shoji S, Uchida K, Tazawa R, Saito W, Kuroda A, Sekiguchi H, Ishii D, Inoue S, Inoue G, Takaso M
- Journal Title
  
  Bio-Medical Materials and Engineering
  
  Volume: - Issue: 4 Pages: 207-215
- DOI
  10.3233/bme-201172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18546, KAKENHI-PROJECT-20K23008, KAKENHI-PROJECT-18K09079, KAKENHI-PROJECT-21H03059, KAKENHI-PROJECT-21K20978
[Journal Article] Wrapping with Basic Fibroblast Growth Factor-Impregnated Collagen Sheet Reduces Rat Sciatic Nerve Allodynia2019
- Author(s)
  Mukai M, Uchida K, Hirosawa N, Murakami K, Kuniyoshi K, Inoue G, Miyagi M, Sekiguchi H, Shiga Y, Inage K, Orita S, Suzuki T, Matsuura Y, Takaso M, Ohtori S
- Journal Title
  
  J Orthop Res
  
  Volume: 37 Issue: 10 Pages: 2258-2263
- DOI
  10.1002/jor.24349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18546, KAKENHI-PROJECT-17K10944, KAKENHI-PROJECT-17K10982
[Presentation] 局所硬化ゼラチンゲルを用いた人工骨へのbFGF導入法を用いた骨折治療法の有用性に関する検討2023
- Author(s)
  齋藤広樹, 内田健太郎, 武田空悟, 松本光圭, 庄司真太郎, 宮城正行, 齋藤亘, 関口裕之, 井上玄, 高相晶士
- Organizer
  第38回　日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-21H03059
[Presentation] BMP-2含有局所硬化ヒアルロン酸ゲルを用いた難治性骨折治療法の有用性2023
- Author(s)
  齋藤広樹, 内田健太郎, 庄司真太郎, 関口裕之, 宮城正行, 福島健介, 井上玄, 高相晶士
- Organizer
  第42回　日本運動器移植再生医学研究会
- Data Source
  KAKENHI-PROJECT-21H03059
[Presentation] 塩基性線維芽細胞増殖因子と間葉系幹細胞スフェロイドの併用による骨形成促進2023
- Author(s)
  武田空悟, 内田健太郎, 齋藤広樹, 黒田晃義, 松本光圭, 関口裕之, 宮城正行, 井上玄, 高相晶士
- Organizer
  第38回　日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-21H03059
[Presentation] 間葉系幹細胞スフェロイドの機能と塩基性線維芽細胞増殖因子の併用による骨形成促進効果の検討2023
- Author(s)
  武田空悟, 内田健太郎, 齋藤広樹, 黒田晃義, 松本光圭, 関口裕之, 宮城正行, 井上玄, 氏平政伸, 高相晶士
- Organizer
  第42回　日本運動器移植再生医学研究会
- Data Source
  KAKENHI-PROJECT-21H03059
[Presentation] 局所硬化ゲルを用いた人工骨へのBMP-2導入法を用いた難治性骨折治療法の有用性に関する検討2022
- Author(s)
  齋藤広樹, 内田健太郎, 黒田晃義, 庄司真太郎, 宮城正行, 齋藤亘, 関口裕之, 井上玄, 高相晶士
- Organizer
  第３７回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-21H03059
[Presentation] スフェロイドサイズが間葉系幹細胞の栄養因子発現に及ぼす影響の検討2022
- Author(s)
  黒田晃義, 内田健太郎, 峰尾歩, 庄司真太郎, 関口裕之, 齋藤亘, 井上玄, 高相晶士
- Organizer
  第３７回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-21H03059
[Presentation] BMP-2含有局所硬化ヒアルロン酸ゲルを用いた広範囲骨欠損修復法の有用性2021
- Author(s)
  庄司真太郎, 内田健太郎, 田澤諒, 関口裕之, 井上玄, 齋藤亘, 宮城正行, 黒田晃義, 高相晶士
- Organizer
  第３６回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K18546
[Presentation] BMP-2含有局所硬化ヒアルロン酸ゲルを用いた広範囲骨欠損修復法の有用性2021
- Author(s)
  庄司真太郎, 内田健太郎, 田澤諒, 関口裕之, 井上玄, 齋藤亘, 宮城正行, 黒田晃義, 高相晶士
- Organizer
  第３６回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-21H03059
[Presentation] BMP-2含有局所硬化ヒアルロン酸ゲルを用いた難治性骨折治療法の有用性2020
- Author(s)
  庄司真太郎、内田健太郎、関口裕之、井上　玄、齋藤亘、宮城正行、村田幸佑、川久保歩、高相晶士
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K18546

1. Uchida Kentaro (50547578)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. 馬渕洋 (50424172)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Saito Wataru (60439099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 大鳥精司 (40361430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 小出隆規 (70322253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 井上玄 (80594209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
7. 高野昇太郎 (10596505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 廣澤直也 (10882748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SEKIGUCHI HIROYUKI 関口 裕之

Sekiguchi Hiroyuki 関口 裕之

Research Projects

Research Products

Co-Researchers

細菌由来血管新生因子を応用した新規血管新生促進因子の創生と骨再生への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Musculoskeletal Regeneration Techniques through the Construction of a Platform for Functional Organoid Fabrication and Local Delivery

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effect of growth factor/In Situ-Formed Hydrogel / Artificial bone Composites on Bone Formation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cell and Growth factor deliverly using in situ formed hydrogel for treatment of bone defectPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] In situ-formed hyaluronan gel/BMP-2/hydroxyapatite composite promotes bone union in refractory fracture model mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of spheroid size on gene expression profiles of a mouse mesenchymal stem cell line in spheroid culture2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of Bone Morphogenetic Protein-2 (BMP-2)/Hydroxyapatite/In Situ-Formed Hyaluronan Hydrogel Composites on Bone Formation in a Murine Model of Posterolateral Lumbar Fusion2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression of nerve growth factor in the callus during fracture healing in a fracture model in aged mice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acceleration of bone formation using in situ-formed hyaluronan-hydrogel containing bone morphogenetic protein-2 in a mouse critical size bone defect model2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Wrapping with Basic Fibroblast Growth Factor-Impregnated Collagen Sheet Reduces Rat Sciatic Nerve Allodynia2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] 局所硬化ゼラチンゲルを用いた人工骨へのbFGF導入法を用いた骨折治療法の有用性に関する検討2023

Author(s)

Organizer

Data Source

[Presentation] BMP-2含有局所硬化ヒアルロン酸ゲルを用いた難治性骨折治療法の有用性2023

Author(s)

Organizer

Data Source

[Presentation] 塩基性線維芽細胞増殖因子と間葉系幹細胞スフェロイドの併用による骨形成促進2023

Author(s)

Organizer

Data Source

[Presentation] 間葉系幹細胞スフェロイドの機能と塩基性線維芽細胞増殖因子の併用による骨形成促進効果の検討2023

Author(s)

Organizer

Data Source

[Presentation] 局所硬化ゲルを用いた人工骨へのBMP-2導入法を用いた難治性骨折治療法の有用性に関する検討2022

Author(s)

Organizer

Data Source

[Presentation] スフェロイドサイズが間葉系幹細胞の栄養因子発現に及ぼす影響の検討2022

SEKIGUCHI HIROYUKI 関口裕之

Sekiguchi Hiroyuki 関口裕之