Onoe Takashi 尾上隆司

… Alternative Names

ONOE Takashi 尾上隆司

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Researcher Number	90549809
Other IDs
Affiliation (Current)	2025: 独立行政法人国立病院機構(呉医療センター臨床研究部), その他部局等, その他
Affiliation (based on the past Project Information) *help	2025: 独立行政法人国立病院機構(呉医療センター臨床研究部), その他部局等, その他 2017 – 2023: 独立行政法人国立病院機構(呉医療センター臨床研究部), その他部局等, その他 2015 – 2017: 独立行政法人国立病院機構(呉医療センター臨床研究部), 免疫応用科学研究室, 室長 2014 – 2015: 独立行政法人国立病院機構(呉医療センター臨床研究部), その他部局等, その他 2013: 独立行政法人国立病院機構(呉医療センター臨床研究部), その他部局等, 研究室長 … More 2012: 独立行政法人国立病院機構(呉医療センター臨床研究部), 研究室長 2012: 独立行政法人国立病院機構(呉医療センター臨床研究部), その他部局等, その他 2012: 独立行政法人国立病院機構(呉医療センター臨床研究部), 臨床研究部, 室長 2012: 独立行政法人国立病院機構, 臨床研究部, 室長 2010 – 2011: Hiroshima University, 病院, 病院助教 2009: Hiroshima University, 病院, 医科診療医 Less
Review Section/Research Field	Principal Investigator General surgery / Basic Section 55010:General surgery and pediatric surgery-related Except Principal Investigator General surgery
Keywords	Principal Investigator 免疫逃避 / 癌微小環境 / 微小環境 / 腫瘍免疫 / PD-L1 / 類洞内皮細胞 / 免疫寛容 / 腫瘍血管内皮 / エクソソーム / 腫瘍内皮細胞 … More / 腫瘍血管内皮細胞 / 癌免疫 / クロストーク / 内皮細胞 / 類同内皮細胞 / 抗原提示 / シアストレス / キメラ / 移植免疫 / 肝移植 … More Except Principal Investigator B細胞 / 臓器移植 / 拒絶反応 / 寛容誘導 / 移植免疫 / 脱感作 / 免疫寛容 / Ｂ細胞 / 血液型不適合 / CD1d / 抗体関連拒絶反応 Less

RAGE-RAGEリガンドaxisを介した腫瘍血管細胞による腫瘍免疫逃避機構の解明Principal Investigator
- Principal Investigator
  
  尾上隆司
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kure Medical Center
癌微小環境由来免疫抑制性エクソソームによる癌免疫逃避機構の解析Principal Investigator
- Principal Investigator
  
  尾上隆司
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kure Medical Center
A study for novel mechanism underlying tumor immune-evasion through tumor endothelial cells as immune suppressive antigen presenting cellsPrincipal Investigator
- Principal Investigator
  
  Onoe Takashi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Department of Clinical Research, National Hospital Organization Kure Medical Center
Development of a novel desensitization/immune-regulatory method by use of multi-potent suppressor B cells to induce immune-tolerance in allogeneic organ transplantation
- Principal Investigator
  
  OHDAN Hideki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  Hiroshima University
A study for immunological feature of tumor endothelial cells (TEC) in immune evasion mechanism of tumor micro-environment and development of a novel anti-cancer therapyPrincipal Investigator
- Principal Investigator
  
  Onoe Takashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Department of Clinical Research, National Hospital Organization Kure Medical Center
Establishment of strategies to regulate antibody-mediated rejection on the basis of B cell differentiation biology
- Principal Investigator
  
  OHDAN Hideki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Hiroshima University
Postoperative portal hypertension promotes alloimmune responses in recipients after LDLT by impairing antigen presenting capacity of LSECs under sheer stress.Principal Investigator
- Principal Investigator
  
  ONOE Takashi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  独立行政法人国立病院機構(呉医療センター臨床研究部)
  Hiroshima University
Development of novel cellular therapy for T cell mediated rejection via direct and indirect pathway using regulatory liver sinusoidal endothelial cells (LSEC) in transplantationPrincipal Investigator
- Principal Investigator
  
  ONOE Takashi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General surgery
- Research Institution
  Hiroshima University

All 2022 2020 2019 2018 2016 2015 2014 2013 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] 腫瘍免疫逃避における腫瘍血管内皮細胞の免疫学的役割2022
- Author(s)
  尾上隆司、田口和浩、大段秀樹
- Journal Title
  
  日本免疫治療学会誌
  
  Volume: 10 Pages: 10-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08947
[Journal Article] Tumor endothelial cell-mediated antigen-specific T-cell suppression via the PD-1/PD-L1 pathway2020
- Author(s)
  Taguchi Kazuhiro、Onoe Takashi、Yoshida Tomoaki、Yamashita Yoshinori、Tanaka Yuka、Ohdan Hideki
- Journal Title
  
  Molecular Cancer Research
  
  Volume: - Issue: 9 Pages: 1427-1440
- DOI
  10.1158/1541-7786.mcr-19-0897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10573, KAKENHI-PROJECT-19H01057
[Journal Article] Isolation of tumor endothelial cells from murine cancer2019
- Author(s)
  Taguchi Kazuhiro、Onoe Takashi、Yoshida Tomoaki、Yamashita Yoshinori、Taniyama Kiyomi、Ohdan Hideki
- Journal Title
  
  Journal of Immunological Methods
  
  Volume: 464 Pages: 105-113
- DOI
  10.1016/j.jim.2018.11.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10573
[Journal Article] Fc-Gamma Receptor Polymorphisms Predispose Patients to Infectious Complications After Liver Transplantation.2016
- Author(s)
  Shimizu S, Tanaka Y, Tazawa H, Verma S, Onoe T, Ishiyama K, Ohira M, Ide K, Ohdan H.
- Journal Title
  
  Am J Transplant.
  
  Volume: 16(2) Issue: 2 Pages: 625-633
- DOI
  10.1111/ajt.13492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15476, KAKENHI-PROJECT-25462008
[Journal Article] Prophylactic managements of hepatitis B viral infection in liver transplantation.2016
- Author(s)
  Onoe T, Tahara H, Tanaka Y, Ohdan H.
- Journal Title
  
  World J Gastroenterol
  
  Volume: 22 Issue: 1 Pages: 165-175
- DOI
  10.3748/wjg.v22.i1.165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462008
[Journal Article] The Role of Liver Sinusoidal Endothelial Cells in Induction of Carbohydrate Reactive B Cells Tolerance Through the Programmed Death 1/Programmed Death Ligand 1 Pathway2015
- Author(s)
  Igarashi Y, Onoe T, Ohdan H.
- Journal Title
  
  Transplantation
  
  Volume: 99(11) Issue: 11 Pages: 2325-2336
- DOI
  10.1097/tp.0000000000000831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02555, KAKENHI-PROJECT-25462008
[Journal Article] Xenograft tolerance and immune function of human T cells developing in pig thymus xenografts.2014
- Author(s)
  Kalscheuer H, Onoe T, Dahmani A, Li HW, Hölzl M, Yamada K, Sykes M.
- Journal Title
  
  J Immunol
  
  Volume: 192(7) Issue: 7 Pages: 3442-3450
- DOI
  10.4049/jimmunol.1302886
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462008
[Journal Article] Attenuation of Portal Hypertension by Continuous Portal Infusion of PGE1 and Immunologic Impact in Adult-to-Adult Living-Donor Liver Transplantation.2013
- Author(s)
  Onoe T., Tanaka Y., Ide K., Ishiyama K., Oshita A., Kobayashi T., Amano H., Tashiro H., and Ohdan H.
- Journal Title
  
  Transplantation
  
  Volume: 95(12) Pages: 1521-1527
- Data Source
  KAKENHI-PROJECT-23791486
[Journal Article] Attenuation of Portal Hypertension by Continuous Portal Infusion of PGE1 and Immunologic Impact in Adult-to-Adult Living-Donor Liver Transplantation.2013
- Author(s)
  Onoe T
- Journal Title
  
  Transplantation
  
  Volume: Epub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791486
[Journal Article] Conditional ablation of HMGB 1 in mice reveals its protective function a gainst endotoxemia and bacterial infection2013
- Author(s)
  Yanai, H, et al.
- Journal Title
  
  Proc. Natl. Acad. Sci. U S A.
  
  Volume: 51 Issue: 51 Pages: 20699-20704
- DOI
  10.1073/pnas.1320808110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04258, KAKENHI-PLANNED-22114007, KAKENHI-PROJECT-23590563, KAKENHI-PROJECT-24590574, KAKENHI-PROJECT-25462008
[Journal Article] Surgical treatment for portosystemic encephalopathy in patients with liver cirrhosis: Occlusion of portosystemic shunt in combination with splenectomy.2013
- Author(s)
  Tashiro H., Ide K., Amano H., Kobayashi T., Onoe T., Ishiyama K., Kuroda S., Tazawa H., Kono H., Aikata H., Takahashi S., Chayama K., and Ohdan H.
- Journal Title
  
  Hepatol Res.
  
  Volume: 43(3) Pages: 249-54
- NAID
  10031183466
- Data Source
  KAKENHI-PROJECT-23791486
[Journal Article] Evidence for the immunosuppressive potential of calcineurin inhibitor sparing in liver transplant recipients with impaired renal function2012
- Author(s)
  Ide K, Tanaka Y, Onoe T, Banshodani M, Tazawa H, Igarashi Y, Basnet NB, Doskali M, Tashiro H, Ohdan H
- Journal Title
  
  J Transplant
  
  Volume: (In press) Pages: 1-6
- DOI
  10.1155/2011/483728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591748, KAKENHI-PROJECT-23659614
[Journal Article] Optimization of immunosuppressive therapy based on a multiparametric mixed lymphocyte reaction assay reduces infectious complications and mortality in living donor liver transplant recipients.2012
- Author(s)
  Tanaka Y., Tashiro H., Onoe T., Ide K., Ishiyama K., and Ohdan H.
- Journal Title
  
  Transplant Proc.
  
  Volume: 44(2) Pages: 555-9
- Data Source
  KAKENHI-PROJECT-23791486
[Journal Article] Adoptive Transfer of Allogeneic Liver Sinusoidal Endothelial Cells Specifically Inhibits T Cell Responses to Cognate Stimuli2012
- Author(s)
  Banshodani M., Onoe T., Shishida M., Tahara H., Hashimoto S., Igarashi Y., Tanaka Y., and Ohdan H.
- Journal Title
  
  Cell Transplant
  
  Volume: (Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-23791486
[Journal Article] マウスB細胞in vitro活性化モデルにおける各種免疫抑制剤感受性2012
- Author(s)
  山下正博, 田澤宏文, 田中友加, 伊禮俊充, 五十嵐友香, 安部智之, 橋本慎二, 平田文宏, 森本博司, 寺岡義布史, 堀田龍一, 井手健太郎, 石山宏平, 尾上隆司, 田代裕尊, 大段秀樹
- Journal Title
  
  今日の移植
  
  Volume: 25 Pages: 236-238
- Data Source
  KAKENHI-PROJECT-23659614
[Journal Article] マウスB細胞 in vitro 活性化モデルにおける各種免疫抑制剤感受性2012
- Author(s)
  山下正博, 田澤宏文, 田中友加, 伊禮俊充, 五十嵐友香, 安部智之, 橋本慎二, 平田文宏, 森本博司, 寺岡義布史, 堀田龍一, 井手健太郎, 石山宏平, 尾上隆司,田代裕尊, 大段秀樹.
- Journal Title
  
  今日の移植
  
  Volume: 25 Pages: 236-238
- Data Source
  KAKENHI-PROJECT-23659614
[Journal Article] 過小グラフト肝移植時のシアストレスによる肝由来免疫抑制能の破綻とその制御法に与えるシクロスポリンの影響2012
- Author(s)
  尾上　隆司
- Journal Title
  
  今日の移植
  
  Volume: 25 Pages: 491-494
- Data Source
  KAKENHI-PROJECT-23791486
[Journal Article] Suppression of immune responses by nonimmunogenic oligodeoxynucleotides with high affinity for high-mobility group box proteins (HMGBs)2011
- Author(s)
  Yanai H, Chiba S, Ban T, Nakaima Y, Onoe T, Honda K, Ohdan H, Taniguchi T.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: Jul 12;108(28) Pages: 11542-11547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791486
[Journal Article] Kinetics of cellular and humoral immunity in a successful case positive kidney transplantation : a case report2011
- Author(s)
  Tanimine N, Ide K, Yamashita M, Tanaka Y, Igarashi Y, Banshodani M, Tazawa H, Basnet NB, Doskali M, Onoe T, Tashiro H, Ohdan H
- Journal Title
  
  Transplant Proc
  
  Volume: 43 Issue: 6 Pages: 2411-2414
- DOI
  10.1016/j.transproceed.2011.05.039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591748, KAKENHI-PROJECT-23659614
[Journal Article] 広島大学における ABO 不適合肝移植の現況と iNKT細胞制御による特異的減感作療法の可能性2011
- Author(s)
  田澤宏文, 伊禮俊充, 五十嵐友香, 田中友加, 尾上隆司, 井手健太郎, 田原裕之, 番匠谷将孝, 小林剛, 大下彰彦, 天野尋暢, 田代裕尊, 大段秀樹
- Journal Title
  
  ABO 血液型不適合移植の新戦略-2011
  
  Pages: 48-56
- Data Source
  KAKENHI-PROJECT-23659614
[Journal Article] Kinetics of cellular and humoral immunity in a successful case of positive crossmatch kidney transplantation: a case report2011
- Author(s)
  Tanimine N, Ide K, Yamashita M, Tanaka Y, Igarashi Y, Banshodani M, Tazawa H, Basnet NB, Doskali M, Onoe T, Tashiro H, Ohdan H
- Journal Title
  
  Transplant Proc
  
  Volume: 43 Pages: 2411-2414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659614
[Journal Article] 広島大学におけるABO血液型不適合肝移植の現況とiNKT細胞制御による特異的減感作療法の可能性2011
- Author(s)
  田澤宏文、伊禮俊充, 五十嵐友香, 田中友加, 尾上隆司, 井手健太郎, 田原裕之, 番匠谷将孝, 小林剛, 大下彰彦, 天野尋暢, 田代裕尊, 大段秀樹.
- Journal Title
  
  ABO血液型不適合移植の新戦略-2011
  
  Volume: なし Pages: 48-56
- Data Source
  KAKENHI-PROJECT-23659614
[Journal Article] Suppression of immune responses by nonimmunogenic oligodeoxynucleotides with high affinity for high-mobility group box proteins (HMGBs).2011
- Author(s)
  Yanai H., Chiba S., Ban T., Nakaima Y., Onoe T., Honda K., Ohdan H., and Taniguchi T.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 108(28) Pages: 11542-7
- Data Source
  KAKENHI-PROJECT-23791486
[Journal Article] Evidence for the immunosuppressive potential of calcineurin inhibitor-sparing regimens in liver transplant recipients with impaired renal function2011
- Author(s)
  Ide K, Tanaka Y, Onoe T, Banshodani M, Tazawa H, Igarashi Y, Basnet NB, Doskali M, Tashiro H, Ohdan H
- Journal Title
  
  J Transplant
- NAID
  40020386785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659614
[Journal Article] Distinct requirements for achievement of allotolerance versus reversal of autoimmunity via nonmyeloablative mixed chimerism induction in NOD mice.2010
- Author(s)
  Nikolic B, Onoe T, et al.
- Journal Title
  
  Transplantation 89(1)
  
  Pages: 23-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890155
[Journal Article] T細胞の経口トレランス誘導と肝類洞内皮細胞2010
- Author(s)
  尾上隆司
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 54 Pages: 601-604
- NAID
  40017405375
- Data Source
  KAKENHI-PROJECT-21890155
[Journal Article] Homeostatic expansion and phenotypic conversion of human T cells depend on peripheral interactions with APCs.2010
- Author(s)
  Onoe T, Kalscheuer H, et al.
- Journal Title
  
  J Immunol 184(12)
  
  Pages: 6756-6765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890155
[Journal Article] T細胞の経口トレランス誘導と肝類洞内皮細胞2010
- Author(s)
  尾上隆司
- Journal Title
  
  臨床免疫・アレルギー科 54巻
  
  Pages: 601-604
- NAID
  40017405375
- Data Source
  KAKENHI-PROJECT-21890155
[Journal Article] Homeostatic expansion and phenotypic conversion of human T cells depend on peripheral interactions with APCs.2010
- Author(s)
  Onoe T
- Journal Title
  
  Journal of Immunology
  
  Volume: 184 Pages: 6756-6765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890155
[Presentation] Novel mechanism underlying tumor immune-evasion across through tumor endothelial cells2018
- Author(s)
  Taguchi Kazuhiro、Onoe Takashi
- Organizer
  AACR(American Association of Cancer Research) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10573
[Presentation] FcγRの遺伝子多型が及ぼすリツキシマブB細胞抑制効果への影響2015
- Author(s)
  坂井寛, 田中友加, 清水誠一, 井手健太郎, 広瀬貴行, 田中飛鳥, 矢野琢也, 佐伯吉弘, 谷峰直樹, 大平真裕, 田原裕之, 石山宏平, 尾上隆司, 田代裕尊, 大段秀樹.
- Organizer
  第51回日本移植学会総会
- Place of Presentation
  熊本
- Year and Date
  2015-10-01
- Data Source
  KAKENHI-PROJECT-15H02555
[Presentation] The Impact and Mechanism of Postoperative Portal Hypertension on Alloimmune Responses After Living Donor Liver Transplantation2013
- Author(s)
  Onoe T, Hashimoto S, Tanaka Y, Ohdan H.
- Organizer
  Rising Star Award, The ILTS 19th Annual International Congress
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-23791486
[Presentation] The Impact and Mechanism of Postoperative Portal Hypertension on Alloimmune Responses After Living Donor Liver Transplantation.2013
- Author(s)
  Onoe T
- Organizer
  The ILTS 19th Annual International Congress
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-23791486
[Presentation] 門脈圧亢進下での拒絶反応更新メカニズムの解析2012
- Author(s)
  橋本慎二,尾上隆司,田中友加,大段秀樹他
- Organizer
  第48回日本移植学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23791486
[Presentation] 肝過小グラフトにおける免疫応答亢進メカニズムの解析2012
- Author(s)
  橋本慎二,尾上隆司,田中友加,大段秀樹他
- Organizer
  第39回日本臓器保存生物医学会学術集会
- Place of Presentation
  福島
- Data Source
  KAKENHI-PROJECT-23791486
[Presentation] 各種免疫抑制剤のB細胞に対する抑制効果について2012
- Author(s)
  田澤宏文,山下正博, 田中友加, 五十嵐友香, 安部智之, 橋本慎二, 平田文宏, 森本博司, 寺岡義布史, 堀田龍一, 井手健太郎, 石山宏平, 尾上隆司, 田代裕尊, 大段秀樹.
- Organizer
  第45回日本臨床腎移植学会
- Place of Presentation
  長野
- Data Source
  KAKENHI-PROJECT-23659614
[Presentation] 過小グラフトにおける肝由来免疫寛容性の解析2012
- Author(s)
  橋本慎二,尾上隆司,田中友加,大段秀樹他
- Organizer
  第30回日本肝移植研究会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23791486
[Presentation] Liver Sinusoidal Endothelial Cells of Small-for-Size Grafts Lose Their Immunosuppressive Function Against Allogeneic T Cells2012
- Author(s)
  Hashimoto S, Onoe T, Tanaka Y, Ohdan H.
- Organizer
  American Transplantation Congress 2012American Transplantation Congress 2012
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-23791486
[Presentation] Impact of postoperative portal hypertension on alloimmune responses after living donor liver transplant2012
- Author(s)
  Tanaka Y, Onoe T, Hashimoto S, Ohdan H. et al.
- Organizer
  24th International congress of the transplantation society
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-23791486
[Presentation] 各種免疫抑制剤の B 細胞に対する抑制効果について.2012
- Author(s)
  田澤宏文, 山下正博, 田中友加, 五十嵐友香, 安部智之, 橋本慎二, 平田文宏, 森本博司, 寺岡義布史, 堀田龍一, 井手健太郎, 石山宏平, 尾上隆司, 田代裕尊, 大段秀樹
- Organizer
  第45回日本臨床腎移植学会
- Place of Presentation
  長野
- Data Source
  KAKENHI-PROJECT-23659614
[Presentation] iNKT 細胞制御による新たなる血液型不適合移植に対する減感作法2011
- Author(s)
  田澤宏文, 伊禮俊充, 田中友加, 五十嵐友香, 尾上隆司, 井手健太郎, 番匠谷将孝, 小林剛, 大下彰彦, 天野尋暢, 田代裕尊, 大段秀樹
- Organizer
  第29回日本肝移植研究会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23659614
[Presentation] 血液型B型に応答するB-細胞は、血液型A型に応答するB-細胞と異なる2011
- Author(s)
  山下正博,田澤宏文, 田中友加, 伊禮俊充, 五十嵐友香, 平田文宏, 安部智之, 橋本慎二, 森本博司, 寺岡義布史, 堀田龍一, 番匠谷将孝, 井手健太郎, 石山宏平, 尾上隆司, 大段秀樹.
- Organizer
  第29回日本肝移植研究会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23659614
[Presentation] Continuous portal infusion of PGE1 attenuates portal hypertension and alloimmune responses in adult-to-adult living donor liver transplantation2011
- Author(s)
  Onoe T, Hashimoto S, Tanaka Y, Ohdan H. et al.
- Organizer
  Congress of Asia Society of Transplantation 2011
- Place of Presentation
  Seoul, Korea
- Year and Date
  2011-09-25
- Data Source
  KAKENHI-PROJECT-23791486
[Presentation] 血液型抗原に対する特異的減感作療法の可能性2011
- Author(s)
  田澤宏文, 伊禮俊充, 田中友加, 五十嵐友香, 尾上隆司, 井手健太郎, 田原裕之, 番匠谷将孝, 小林剛, 大下彰彦, 天野尋暢, 　田代裕尊, 大段秀樹.
- Organizer
  第18回ABO血液型不適合移植研究会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659614
[Presentation] 血液型不適合肝移植後の長期経過における抗血液型反応寛容化の証明2011
- Author(s)
  田澤宏文,伊禮俊充, 田中友加, 五十嵐友香, 尾上隆司, 井手健太郎, 番匠谷将孝, 小林剛, 大下彰彦, 天野尋暢, 田代裕尊, 大段秀樹.
- Organizer
  第66回日本消化器外科学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659614
[Presentation] 過小グラフトを用いた生体部分肝移植に対するPGE門脈持続注入療法の有用性の検討2011
- Author(s)
  尾上隆司,橋本慎二,田中友加,大段秀樹他
- Organizer
  第29回日本肝移植研究会
- Place of Presentation
  仙台
- Year and Date
  2011-07-21
- Data Source
  KAKENHI-PROJECT-23791486
[Presentation] 血液型不適合移植後の長期経過における抗血液型反応寛容化の証明2011
- Author(s)
  田澤宏文, 伊禮俊充, 田中友加, 五十嵐友香, 尾上隆司, 井手健太郎, 番匠谷将孝, 小林剛, 大下彰彦, 天野尋暢, 田代裕尊, 大段秀樹
- Organizer
  第66回日本消化器外科学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659614
[Presentation] プロテアソーム阻害剤(ボルテゾミブ)の B 細胞に対する免疫抑制効果の検討と既存抗体陽性腎移植における臨床応用の経験2011
- Author(s)
  田澤宏文, 井手健太郎, 伊禮俊充, 五十嵐友香, 田中友加, 尾上隆司, 石山宏平, 田代裕尊, 大段秀樹.
- Organizer
  第47回日本移植学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23659614
[Presentation] 血液型抗原に対する B 細胞免疫応答～A 型抗原と B 型抗原への応答は異なる～.2011
- Author(s)
  山下正博, 田澤宏文, 田中友加, 伊禮俊充, 五十嵐友香, 平田文宏, 安部智之, 橋本慎二, 森本博司, 寺岡義布史, 堀田龍一, 井手健太郎, 石山宏平, 尾上隆司,大段秀樹
- Organizer
  第18回 ABO 血液型不適合移植研究会.
- Place of Presentation
  名古屋
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-23659614
[Presentation] iNKT細胞制御による新たなる血液型不適合移植に対する減感作法2011
- Author(s)
  田澤宏文,伊禮俊充, 田中友加, 五十嵐友香, 尾上隆司, 井手健太郎, 番匠谷将孝, 小林剛, 大下彰彦, 天野尋暢, 田代裕尊, 大段秀樹.
- Organizer
  第29回日本肝移植研究会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23659614
[Presentation] 血液型抗原に対するB細胞免疫応答　～A型抗原とB型抗原への応答は異なる～2011
- Author(s)
  山下正博,田澤宏文, 田中友加, 伊禮俊充, 五十嵐友香, 平田文宏, 安部智之, 橋本慎二, 森本博司, 寺岡義布史, 堀田龍一, 井手健太郎, 石山宏平, 尾上隆司, 大段秀樹.
- Organizer
  第18回ABO血液型不適合移植研究会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659614
[Presentation] 生体部分肝移植後のPGE1門脈注入療法を用いた過小グラフト症候群治療の検討2011
- Author(s)
  尾上隆司,橋本慎二,田中友加,大段秀樹他
- Organizer
  第111回日本外科学会定期学術集会
- Place of Presentation
  東京
- Year and Date
  2011-05-26
- Data Source
  KAKENHI-PROJECT-23791486
[Presentation] プロテアソーム阻害剤（ボルテゾミブ）のB細胞に対する免疫抑制効果の検討と既存抗体陽性腎移植における臨床応用の経験2011
- Author(s)
  田澤宏文,井手健太郎, 伊禮俊充, 五十嵐友香, 田中友加, 尾上隆司, 石山宏平, 田代裕尊, 大段秀樹.
- Organizer
  第47回日本移植学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23659614
[Presentation] 生体部分肝移植後のPGE1門脈注入療法を用いた過小グラフト症候群治療の検討.2011
- Author(s)
  尾上　隆司
- Organizer
  第111回日本外科学会定期学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791486
[Presentation] 血液型抗原に対する特異的減感作療法の可能性2011
- Author(s)
  田澤宏文, 伊禮俊充, 田中友加, 五十嵐友香, 尾上隆司, 井手健太郎, 田原裕之, 番匠谷将孝, 小林剛, 大下彰彦, 天野尋暢, 田代裕尊, 大段秀樹.
- Organizer
  第18回 ABO 血液型不適合移植研究会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-23659614
[Presentation] 血液型 B 型に応答する B 細胞は血液型 A 型に応答する B 細胞と異なる2011
- Author(s)
  山下正博, 田澤宏文, 田中友加, 伊禮俊充, 五十嵐友香, 平田文宏, 安部智之, 橋本慎二, 森本博司, 寺岡義布史, 堀田龍一, 井手健太郎, 石山宏平, 尾上隆司,大段秀樹
- Organizer
  第29回日本肝移植研究会.
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23659614
[Presentation] Continuous PGE1 injection via the portal vein for small-for-size graft improves graft function and survival in adult-to-adult living donor liver transplantation.2011
- Author(s)
  Onoe T
- Organizer
  American Transplant Congress
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-23791486
[Presentation] Continuous portal infusion of PGE1 attenuates portal hypertension and alloimmune responses in adult-to-adult living donor liver transplantation2011
- Author(s)
  Onoe T
- Organizer
  Congress of Asia Society of Transplantation, 2011
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-23791486
[Presentation] Continuous PGE1 injection via the portal vein for small-for-size graft improves graft function and survival in adult-to-adult living donor liver transplantation2011
- Author(s)
  Onoe T, Hashimoto S, Tanaka Y, Ohdan H. et al.
- Organizer
  American Transplant Congress 2011
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2011-04-30
- Data Source
  KAKENHI-PROJECT-23791486
[Presentation] 肝類洞内皮細胞の抗原特異的免疫寛容誘導能～ill vivoモデルでの解析～2010
- Author(s)
  番匠谷将孝, 尾上隆司
- Organizer
  第110回日本外科学会定期学術周回
- Place of Presentation
  名古屋
- Year and Date
  2010-04-08
- Data Source
  KAKENHI-PROJECT-21890155
[Presentation] 肝類洞内皮細胞のアロ応答性T細胞制御能:in vivoモデルでの解明2010
- Author(s)
  番匠谷将孝, 尾上隆司
- Organizer
  第46回日本移植学会総会
- Place of Presentation
  京都
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-21890155
[Presentation] Advantageous effect of a continuous injection of PGE1 via the portal vein for small-for size graft in adult-to-adult living donor liver transplantation2010
- Author(s)
  尾上隆司
- Organizer
  The 8th Japan-Korea Transplantation Forum
- Place of Presentation
  京都
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-21890155
[Presentation] Allogeneic Liver Sinusoidal Endothelial Cells Negatively Regulate the Immune Response of Corresponding T Cells in a Liver Endothelium Repopulation Model.2010
- Author(s)
  Banshoudani M, Onoe T, et al.
- Organizer
  American Transplant Congress 2010
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-05-01
- Data Source
  KAKENHI-PROJECT-21890155
[Presentation] 肝類洞内皮細胞の免疫寛容誘導能の解析～肝移植後の免疫寛容をめざした試み2010
- Author(s)
  番匠谷将孝, 尾上隆司
- Organizer
  第28回日本肝移植研究会
- Place of Presentation
  広島
- Year and Date
  2010-07-02
- Data Source
  KAKENHI-PROJECT-21890155
[Presentation] 肝類洞内皮細胞の抗原特異的免疫寛容誘導能～in vivoモデルでの解析～2010
- Author(s)
  番匠谷将孝, 尾上隆司
- Organizer
  第110回日本外科学会定期学術集会
- Place of Presentation
  名古屋
- Year and Date
  2010-04-08
- Data Source
  KAKENHI-PROJECT-21890155
[Presentation] ドナー肝由来活性化リンパ球移入を用いた肝移植後肝癌再発制御法の臨床評価2010
- Author(s)
  尾上隆司
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-21890155
[Presentation] 生体部分肝移植における過小グラフト症候群に対するPGE1門脈注入療法の有用性の検討2010
- Author(s)
  尾上隆司
- Organizer
  第46回日本移植学会総会
- Place of Presentation
  京都
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-21890155
[Presentation] Advantageous effect of a continuous injection of PGE1 via the portal vein for small-for-size graft in adult-to-adult living donor liver transplantation2010
- Author(s)
  尾上隆司
- Organizer
  The 8th Japan-Korea Transplantation Forum
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-21890155
[Presentation] 糖鎖抗原を表出した肝類洞内皮細胞はB細胞の抗体産生を抑制できる2010
- Author(s)
  五十嵐友香, 尾上隆司
- Organizer
  第28回日本肝移植研究会
- Place of Presentation
  広島
- Year and Date
  2010-07-02
- Data Source
  KAKENHI-PROJECT-21890155
[Presentation] 肝類洞内皮細胞の抗原特異的免疫寛容誘導能の解析2010
- Author(s)
  番匠谷将孝, 尾上隆司
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-21890155
[Presentation] LSEC tolerize allo-reactive T cells in a liver endothelium repopulation model.2009
- Author(s)
  Banshoudani M, Onoe T, et al.
- Organizer
  2009 European Society of Organ Transplantation
- Place of Presentation
  Paris, France
- Year and Date
  2009-08-30
- Data Source
  KAKENHI-PROJECT-21890155
[Presentation] Evidence for tolerizing allo reactive T cell by LSECs in a liver endothelium repopulation in vivo model.2009
- Author(s)
  Banshoudani M, Onoe T, et al.
- Organizer
  2009 American Transplantation Congress
- Place of Presentation
  Boston, USA
- Year and Date
  2009-05-30
- Data Source
  KAKENHI-PROJECT-21890155

1. OHDAN Hideki (10363061)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
2. TANAKA Yuka (90432666)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
3. 小林孝彰 (70314010)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 田代裕尊

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Onoe Takashi 尾上 隆司

ONOE Takashi 尾上 隆司

Research Projects

Research Products

Co-Researchers

RAGE-RAGEリガンドaxisを介した腫瘍血管細胞による腫瘍免疫逃避機構の解明Principal Investigator

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癌微小環境由来免疫抑制性エクソソームによる癌免疫逃避機構の解析Principal Investigator

Principal Investigator

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A study for novel mechanism underlying tumor immune-evasion through tumor endothelial cells as immune suppressive antigen presenting cellsPrincipal Investigator

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Development of a novel desensitization/immune-regulatory method by use of multi-potent suppressor B cells to induce immune-tolerance in allogeneic organ transplantation

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A study for immunological feature of tumor endothelial cells (TEC) in immune evasion mechanism of tumor micro-environment and development of a novel anti-cancer therapyPrincipal Investigator

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Establishment of strategies to regulate antibody-mediated rejection on the basis of B cell differentiation biology

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Postoperative portal hypertension promotes alloimmune responses in recipients after LDLT by impairing antigen presenting capacity of LSECs under sheer stress.Principal Investigator

Principal Investigator

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Research Institution

Development of novel cellular therapy for T cell mediated rejection via direct and indirect pathway using regulatory liver sinusoidal endothelial cells (LSEC) in transplantationPrincipal Investigator

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Research Institution

[Journal Article] 腫瘍免疫逃避における腫瘍血管内皮細胞の免疫学的役割2022

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[Journal Article] Tumor endothelial cell-mediated antigen-specific T-cell suppression via the PD-1/PD-L1 pathway2020

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DOI

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[Journal Article] Isolation of tumor endothelial cells from murine cancer2019

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[Journal Article] Fc-Gamma Receptor Polymorphisms Predispose Patients to Infectious Complications After Liver Transplantation.2016

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[Journal Article] Prophylactic managements of hepatitis B viral infection in liver transplantation.2016

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[Journal Article] The Role of Liver Sinusoidal Endothelial Cells in Induction of Carbohydrate Reactive B Cells Tolerance Through the Programmed Death 1/Programmed Death Ligand 1 Pathway2015

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Onoe Takashi 尾上隆司

ONOE Takashi 尾上隆司