Osaka Issey 大坂一生

… Alternative Names

OSAKA Issey 大坂一生

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Researcher Number	90550244
Other IDs
Affiliation (Current)	2026: 富山県立大学, 工学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2025: 富山県立大学, 工学部, 准教授 2013 – 2017: 北陸先端科学技術大学院大学, ナノマテリアルテクノロジーセンター, 講師 2012: 横浜市立大学, 生命ナノシステム科学研究科, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 62010:Life, health and medical informatics-related / Basic Section 34020:Analytical chemistry-related / Analytical chemistry / オミクス計測科学 Except Principal Investigator Basic Section 58020:Hygiene and public health-related: including laboratory approach / Natural medicines / Nanostructural chemistry
Keywords	Principal Investigator 質量分析 / イオンモビリティ / レーザー脱離イオン化 / イメージング / レーザー脱離イオン化法 / 疾患 / 健康予測 / 毛髪メタボロミクス / 質量分析法 / メタボロミクス … More / 毛髪 / バイオマーカー / 網羅的局在解析 / 副腎皮質ホルモン / ステロイド / 分析科学 / SALDI / 表面支援レーザー脱離イオン化法 / 質量分析イメージング / 細胞切片 / 金属薄膜 / スパッタリング / 蒸着 / MALDI / 表面支援レーザー脱離イオン化(SALDI) / 薬物 / 脂質 / エレクトロスプレーイオン化 / 多価イオン / 分配係数 / 気化流速 / イオン化効率 / 疎水性度 / リン酸化ペプチド / ペプチド / イオン収量 / プロテオミクス / ESI … More Except Principal Investigator ステロイド / 機械学習 / 因果推論 / 高血圧 / アルドステロン / 腸内細菌 / 薬理活性 / 化合物ライブラリー / 天然物類縁体 / 生薬 / 多様性拡大抽出物 / 抗菌光線力学療法 / 金属クラスター / 歯周病 / a-PDT / 有機色素 / PDT / 光増感剤 / 金ナノクラスター Less

疾患予測と個別化医療を目指した網羅的ステロイドホルモン解析と機械学習モデルの融合
- Principal Investigator
  
  唐島成宙
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kanazawa University
Health predictions with hair metabolomics using ion mobility mass spectrometryPrincipal Investigator
- Principal Investigator
  
  大坂一生
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  Toyama Prefectural University
Elucidation of the Salt-Sensitive Metabolic Regulatory Network Mediated by Gut Microbiota-Derived Steroid Hormones
- Principal Investigator
  
  Karashima Shigehiro
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kanazawa University
Development of basic analytical technology for diagnosing lifestyle-related diseases derived from adrenocortical hormonesPrincipal Investigator
- Principal Investigator
  
  Osaka Issey
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 34020:Analytical chemistry-related
- Research Institution
  Toyama Prefectural University
多様性拡大抽出物を活用した薬理活性志向型天然化合物類縁体ライブラリーの構築
- Principal Investigator
  
  大島吉輝
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Natural medicines
- Research Institution
  Tohoku University
Development of novel laser desorption ionization with metal filmPrincipal Investigator
- Principal Investigator
  
  Osaka Issey
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Analytical chemistry
- Research Institution
  Toyama Prefectural University
  Japan Advanced Institute of Science and Technology
Novel Gold nanocluster-based Photosensitizers for Antimicrobial Photodynamic Therapy
- Principal Investigator
  
  Kawasaki Hideya
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nanostructural chemistry
- Research Institution
  Kansai University
Study on ion yield of phosphorylated peptides in ESI for proteomic analysisPrincipal Investigator
- Principal Investigator
  
  OSAKA Issey
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  オミクス計測科学
- Research Institution
  Japan Advanced Institute of Science and Technology
  Yokohama City University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Normalization based on m/z shift and ion intensity in SALDI-TOFMS imaging of samples with non-horizontal surface2024
- Author(s)
  Riko Takata, Kotaro Hashimoto, Taichi Shimazaki, Kyosuke Kaneda, Shuhei Yamamoto, Shota Nakanishi, Issey Osaka
- Journal Title
  
  Mass Spectrometry
  
  Volume: 13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K11323
[Journal Article] Direct detection of dithiocarbamate fungicides by SALDI/MS using porous TiC ceramic powder as substrate2024
- Author(s)
  Hiroshi Moriwaki, Issey Osaka, Kotaro Hashimoto, Osamu Yamada
- Journal Title
  
  Analytical Methods
  
  Volume: 16 Pages: 2464-2471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K11323
[Journal Article] Effect of the surface morphology of a metal film on ion yields in a platinum-film surface-assisted laser desorption/ionization mass spectrometry2024
- Author(s)
  Kotaro Hashimoto, Kyosuke Kaneda, Taichi Shimazaki, Chouma Kurihashi, Shuhei Yamamoto, Riko Takata, Shota Nakanishi, Issey Osaka
- Journal Title
  
  Mass Spectrometry
  
  Volume: 13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K11323
[Journal Article] Direct Additive Detection in Polymer Films via Platinum-Assisted SALDI Mass Spectrometry Imaging2024
- Author(s)
  Hideya Kawasaki, Issey Osaka, Ryuichi Arakawa
- Journal Title
  
  Mass Spectrometry
  
  Volume: 13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K11323
[Journal Article] Imaging analysis of phosphatidylcholines and diacylglycerols using surface-assisted laser desorption/ionization mass spectrometry with metal film formed by mist chemical vapor deposition2023
- Author(s)
  Riko Takata, Yuji Nakabayashi, Kotaro Hashimoto, Akio Miyazato, Issey Osaka
- Journal Title
  
  Mass Spectrometry
  
  Volume: 12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K11323
[Journal Article] Rapidity and Precision of Steroid Hormone Measurement2022
- Author(s)
  Karashima Shigehiro、Osaka Issey
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 11 Issue: 4 Pages: 956-956
- DOI
  10.3390/jcm11040956
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10392
[Journal Article] Comprehensive steroid assay with non-targeted analysis using liquid chromatography ion mobility mass spectrometry2022
- Author(s)
  Mai Yamakawa, Shigehiro Karashima, Riko Takata, Taichi Haba, Keigo Kuroiwa, Hideaki Toyama, Atsushi Hashimoto, Daisuke Aono, Mitsuhiro Kometani, Hidetaka Nambo, Takashi Yoneda, Issey Osaka
- Journal Title
  
  Internationalt Journal of Molecular. Science
  
  Volume: 23 Pages: 13858-13858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05531
[Journal Article] Rapidity and Precision of Steroid Hormone Measurement2022
- Author(s)
  Shigehiro Karashima, Issey Osaka
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 11(4) Pages: 956-956
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05531
[Journal Article] 表面支援レーザー脱離イオン化質量分析イメージング法2019
- Author(s)
  大坂一生
- Journal Title
  
  J. Mass Spectrom. Soc. Jpn.
  
  Volume: 67 Pages: 117-122
- NAID
  130007689969
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05531
[Journal Article] 表面支援レーザー脱離イオン化質量分析イメージング法2019
- Author(s)
  大坂一生
- Journal Title
  
  J. Mass Spectrom. Soc. Jpn.
  
  Volume: 4 Pages: 117-122
- NAID
  130007689969
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K17919
[Journal Article] レーザー照射によるイオン化の原理2019
- Author(s)
  大坂一生
- Journal Title
  
  J. Plasma Fusion Res
  
  Volume: 6 Pages: 258-261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K17919
[Journal Article] レーザー照射によるイオン化の原理2019
- Author(s)
  大坂一生
- Journal Title
  
  J. Plasma Fusion Res
  
  Volume: 95 Pages: 258-261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05531
[Journal Article] Novel approach to enhance sensitivity in surface‐assisted laser desorption/ionization mass spectrometry imaging using deposited organic‐inorganic hybrid matrices2019
- Author(s)
  Kazuyoshi Nozaki, Yuji Nakabayashi, Tatsuya Murakami, Akio Miyazato, Issey Osaka
- Journal Title
  
  J Mass Spectrom.
  
  Volume: 54 Pages: 612-619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K17919
[Journal Article] Application of porous TiC ceramic powder as a substrate for the surface-assisted laser desorption/ionization mass spectrometry to detection environmental pollutants2018
- Author(s)
  Hiroshi Moriwaki, Takumi Otsuka, Yukari Kawabe, Issey Osaka, Akio Miyazato, Junpei Maruo, Osamu Yamada
- Journal Title
  
  International Journal of Mass Spectrometry
  
  Volume: 428 Pages: 49-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K17919
[Journal Article] Ag7(MBISA)6 Nanoclusters Conjugated with Quinacrine for FRET-Enhanced Photodynamic Activity under Visible Light Irradiation2018
- Author(s)
  C. Tominaga, D. Hikosou, I. Osaka, H. Kawasaki
- Journal Title
  
  Acta Physico-Chimica Sinica
  
  Volume: －
- Data Source
  KAKENHI-PROJECT-15H03520
[Journal Article] Direct Imaging Mass Spectrometry of Plant Leaves Using Surface-assisted Laser Desorption/Ionization with Sputter-deposited Platinum Film2016
- Author(s)
  T. Ozawa, I. Osaka, H. Kawasaki, R. Arakawa
- Journal Title
  
  Anal. Sci.
  
  Volume: 32 Issue: 5 Pages: 587-591
- DOI
  10.2116/analsci.32.587
- NAID
  130005150936
- ISSN
  0910-6340, 1348-2246
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H03520, KAKENHI-PROJECT-26505011, KAKENHI-PROJECT-16K17919
[Journal Article] Effects of ligand species and cluster size of biomolecule-protected Au nanoclusters on efficiency of singlet-oxygen generation2016
- Author(s)
  M. Yamamoto, I. Osaka, K. Yamashita, H. Hasegawa, R. Arakawa, H. Kawasaki
- Journal Title
  
  J. Lumin.
  
  Volume: 180 Pages: 315-320
- DOI
  10.1016/j.jlumin.2016.08.059
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03520
[Journal Article] Simultaneous detection of phosphatidylcholines and glycerolipids using matrix-enhanced surface assisted laser desorption/ionization-mass spectrometry with sputter-deposited platinum film2015
- Author(s)
  T. Ozawa, I. Osaka, T. Ihozaki, S. Hamada, Y. Kuroda, T. Murakami, A. Miyazato, H. Kawasakia and R. Arakawa
- Journal Title
  
  J. Mass Spectrom.
  
  Volume: 50 Issue: 11 Pages: 1264-1269
- DOI
  10.1002/jms.3700
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26505011, KAKENHI-PROJECT-15H03520
[Journal Article] Optical Properties of 2-Methacryloyloxyethyl Phosphorylcholine-protected Au4 Nanoclusters and Their Fluorescence Sensing of C-reactive Protein2015
- Author(s)
  J. Yoshimoto, A. Sangsuwan, I. Osaka, K. Yamashita, Y. Iwasaki, M. Inada, R. Arakawa, and H. Kawasaki
- Journal Title
  
  J. Phys. Chem. C
  
  Volume: 119 Issue: 25 Pages: 14319-14325
- DOI
  10.1021/acs.jpcc.5b03934
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26505011, KAKENHI-PUBLICLY-26107719, KAKENHI-PROJECT-15H03026, KAKENHI-PROJECT-15H03520
[Journal Article] 5-Amino-1-naphthol, a navel 1,5-naphthalene derivative matrix suitable for matrix-assisted laser desorption/ionization in-source decay of phosphorylated peptides2013
- Author(s)
  I. Osaka, M. Sakai, M. Takayama
- Journal Title
  
  Rapid Commun. Mass Spectrom.
  
  Volume: 27 Issue: 1 Pages: 103-108
- DOI
  10.1002/rcm.6430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24619006
[Journal Article] Two-dimensional Mapping Using Different Chromatographic Separations Coupled with Mass Spectrometry for the Analysis of Ginsenosides in Panax Ginseng Root and Callus2013
- Author(s)
  I. Osaka, H. Hisatomi, Y. Ueno, S. Taira, Y. Sahashi、H. Kawasaki, R. Arakawa
- Journal Title
  
  Anal. Sci.
  
  Volume: 29 Issue: 4 Pages: 429-434
- DOI
  10.2116/analsci.29.429
- NAID
  10031165334
- ISSN
  0910-6340, 1348-2246
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24619006
[Journal Article] Influence of Secondary Structure on In-Source Decay of Protein in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry2012
- Author(s)
  M.Takayama, I.Osaka and M.Sakakura
- Journal Title
  
  Mass Spectrometry
  
  Volume: 1 Issue: 1 Pages: A0001-A0001
- DOI
  10.5702/massspectrometry.A0001
- NAID
  10031126337
- ISSN
  2186-5116, 2187-137X
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23550101, KAKENHI-PROJECT-24619006
[Journal Article] Oligonucleotide analysis by nanoparticle-assisted laser desorption/ionization mass spectrometry2012
- Author(s)
  Shu Taira, Issey Osaka, Shuich Shimma, Daisaku Kaneko, Tomoyuki Hiroki, Yasuko Kawamura-Konishi and Yuko Ichiyanagi
- Journal Title
  
  Analyst
  
  Volume: 137 Issue: 9 Pages: 2006-2010
- DOI
  10.1039/c2an16237g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23656013, KAKENHI-PROJECT-23710124, KAKENHI-PROJECT-24619006
[Presentation] Detection of phospholipids and glycerolipids for SALDI/MS with metal film fabricated by mist CVD2024
- Author(s)
  Riko Takata, Yuji Nalabayashi, Yuki Kato, Shigehiro Karashima, Issey Osaka
- Organizer
  Bio4apps2024, Toyama International Conference Center,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] 粗い試料表面のレーザー脱離イオン化質量分析イメージング法2024
- Author(s)
  髙田莉子、島﨑泰地、金田恭介、橋本虎汰郎、山本周平、中西将太、大坂一生
- Organizer
  分析化学会第73年会
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] Comprehensive metabolomic profiling method for disease by non-target LC/IM/MS/MS2024
- Author(s)
  Ei Horiuchi, Shigehiro Karashima, Issey Osaka
- Organizer
  Bio4apps2024, Toyama International Conference Center,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] ミストCVD成膜金属薄膜を利用した表面支援レーザー脱離イオン化質量分析法によるポリマーの検出2024
- Author(s)
  中村希未、唐島成宙、大坂一生
- Organizer
  日本質量分析学会第72回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] 金属薄膜表面支援レーザー脱離イオン化質量分析イメージング法による副腎における誘導体化ステロイドホルモンの局在解析2024
- Author(s)
  髙田莉子、唐島成宙、大坂一生
- Organizer
  日本質量分析学会第72回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] 液体クロマトグラフィーイオンモビリティー質量分析法によるサプリメント中のステロイドの分析2024
- Author(s)
  小関涼介、唐島成宙、大坂一生
- Organizer
  日本質量分析学会第72回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] SALDI/TOFMSイメージングにおける試料の厚さとm/zシフトの関係2024
- Author(s)
  橋本虎汰郎、島﨑泰地、金田恭介、山本周平、大坂一生
- Organizer
  日本質量分析学会第72回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] A simultaneous analytical method for L- and D-amino acids in blood by LC/IM/MS2024
- Author(s)
  Yuto Tsujino, Anju Asahina, Shigehiro Karashima, Issey Osaka
- Organizer
  Bio4apps2024, Toyama International Conference Center,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] Direct detection of vitamin D analogue by MF-SALDI/MS2024
- Author(s)
  Chouma Kurihashi, Shigehiro Karashima, Issey Osaka
- Organizer
  Bio4apps2024, Toyama International Conference Center,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] イオンモビリティーを用いたLC/MSによる血清中のステロイドホルモンの定量分析および主成分分析2023
- Author(s)
  髙田莉子, 山川舞, 古関涼介, 唐島成宙, 大坂一生
- Organizer
  日本質量分析学会第71回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] イオンモビリティーを用いたLC/MSおよびレーザー脱離イオン化質量分析イメージングによる毛髪中の代謝物の分析2023
- Author(s)
  髙田莉子, 山川舞, 島﨑泰地, 唐島成宙, 大坂一生
- Organizer
  日本質量分析学会第71回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] 高分解能GC-TOFMSを用いた環境汚染分析と代謝物の分析2023
- Author(s)
  大坂一生
- Organizer
  第46回 MSユーザーズミーティング (東京) (JEOL)
- Invited
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] PCA analysis of liquid chromatography ion mobility mass spectrometry data for classification of hypertensive disorders2023
- Author(s)
  I. Osaka, R. Takata, M. Yamakawa, S. Karashima
- Organizer
  AOMSC-KSMS 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] 液体クロマトグラフィーイオンモビリティ質量分析法を用いたノンターゲットステロイドアッセイの開発2023
- Author(s)
  唐島成宙, 山川舞, 高田莉子, 山崎海斗, 小西正剛, 青野大輔, 米谷充弘, 武田仁勇, 米田隆, 大坂一生
- Organizer
  第30回日本ステロイドホルモン学会
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] Simple and Sensitive Analysis for Hair Components by MALDI2023
- Author(s)
  R. Takata, S. Karashima, I. Osaka
- Organizer
  AOMSC-KSMS 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] 液体クロマトグラフィーイオンモビリティ質量分析法による血清中の代謝物のノンターゲット網羅分析とステロイドのターゲット定量分析2023
- Author(s)
  大坂一生, 髙田莉子, 唐島成宙
- Organizer
  日本分析化学会第72年会
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] 血清中の誘導体化アミノ酸と短鎖脂肪酸の網羅分析のための前処理法2023
- Author(s)
  山﨑海斗, 唐島成宙, 大坂一生
- Organizer
  日本質量分析学会第71回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] 高分解能GC-TOFMSを用いた環境汚染分析と代謝物の分析2023
- Author(s)
  大坂一生
- Organizer
  第43回 MSユーザーズミーティング(大阪) (JEOL)
- Invited
- Data Source
  KAKENHI-PROJECT-23K11323
[Presentation] イオンモビリティーを用いたLC/MSによる血清中のステロイドホルモンの定量分析の可能性2022
- Author(s)
  山川舞・唐島成宙・大坂一生
- Organizer
  日本質量分析学会第70回質量分析総合討論会、２P-１８
- Data Source
  KAKENHI-PROJECT-19K05531
[Presentation] 表面支援レーザー脱離イオン化質量分析イメージングによる材料の凹凸表面成分の局在解析2022
- Author(s)
  大坂一生
- Organizer
  日本分析化学会高分子分析研究懇談会412回例会
- Invited
- Data Source
  KAKENHI-PROJECT-19K05531
[Presentation] イオンモビリティーLC/MSを用いた血漿中のアミノ酸とその他の代謝物の同時分析2022
- Author(s)
  山﨑海斗・唐島成宙・大坂一生
- Organizer
  日本質量分析学会第70回質量分析総合討論会、２P-１８
- Data Source
  KAKENHI-PROJECT-19K05531
[Presentation] Novel approach to quantitative analysis of steroids using liquid chromatography mass spectrometry coupled with ion mobility spectrometry2022
- Author(s)
  M. Yamakawa, R Takata, S Karashima, I. Osaka
- Organizer
  Active Enzyme Molecule 2022, BRC-06
- Data Source
  KAKENHI-PROJECT-19K05531
[Presentation] 金属薄膜表面支援レーザー脱離イオン化質量分析法によるステロイドの分析2021
- Author(s)
  島﨑泰地・山川舞・唐島成宙・大坂一生
- Organizer
  第69回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-19K05531
[Presentation] イオンモビリティ-質量分析による低分子量生体分子の一斉分析法の開発2021
- Author(s)
  山川舞・唐島成宙・大坂一生
- Organizer
  日本分析化学会第70年会
- Data Source
  KAKENHI-PROJECT-19K05531
[Presentation] ステロイドのノンターゲットイオンモビリティー質量分析2021
- Author(s)
  山川舞・唐島成宙・大坂一生
- Organizer
  第69回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-19K05531
[Presentation] ステロイドのノンターゲットイオンモビリティー質量分析2021
- Author(s)
  山川舞、唐島成宙、大坂一生
- Organizer
  第69回質量分析総合討論会 May 19-21, 2021 (Web)
- Data Source
  KAKENHI-PROJECT-21K10392
[Presentation] 液体クロマトグラフィー/イオンモビリティ-質量分析による低分子量生体分子の一斉分析法の開発2021
- Author(s)
  山川舞、唐島成宙、大坂一生
- Organizer
  日本分析化学会第70年会 Sep 22-24, 2021 (Web)
- Data Source
  KAKENHI-PROJECT-21K10392
[Presentation] 化学蒸着法による表面支援レーザー脱離イオン化のための金属薄膜の調製2020
- Author(s)
  大坂一生
- Organizer
  第68回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-19K05531
[Presentation] Zr薄膜表面支援レーザー脱離イオン化質量分析法による薬物の高感度検出のための前処理法の評価2019
- Author(s)
  大坂一生
- Organizer
  日本分析化学会第68回年会
- Data Source
  KAKENHI-PROJECT-19K05531
[Presentation] ジルコニウム薄膜を利用したマトリックスエンハンスト表面支援レーザー脱離イオン化質量分析法によるオランザピンの高感度検出2019
- Author(s)
  大坂一生
- Organizer
  日本質量分析学会第67回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-16K17919
[Presentation] 質量分析法を用いた生体分子や薬物の局在分析法2018
- Author(s)
  大坂一生
- Organizer
  富山薬窓会富山・石川合同支部の秋の交流会
- Invited
- Data Source
  KAKENHI-PROJECT-16K17919
[Presentation] 金属薄膜を利用した表面支援レーザー脱離イオン化2018
- Author(s)
  大坂一生
- Organizer
  第11回北陸合同バイオシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K17919
[Presentation] 金属薄膜表面支援レーザー脱離イオン化質量分析イメージング法による薬物の分析2018
- Author(s)
  大坂一生
- Organizer
  平成３０年度トメックス(富山医薬品化学研究会)第１７回研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16K17919
[Presentation] 有機マトリックスを共存させた金属薄膜表面支援レーザー脱離イオン化イメージング質量分析法によるマウス肝ホモジネート切片中のオランザピンの検出2017
- Author(s)
  野崎和吉、大坂一生
- Organizer
  日本質量分析学会第65回質量分析総合討論会 2017 つくば
- Data Source
  KAKENHI-PROJECT-16K17919
[Presentation] Pt蒸着支援脱離イオン化を用いた様々な表面のMSイメージング解析2017
- Author(s)
  小澤智行、大坂一生、川崎英也、荒川隆
- Organizer
  日本分析化学会第66年会
- Data Source
  KAKENHI-PROJECT-16K17919
[Presentation] 金属薄膜を利用する表面支援レーザー脱離イオン化法による生体組織の質量分析イメージング2017
- Author(s)
  大坂一生、仲林裕司、宮里朗夫
- Organizer
  日本分析化学会第66年会
- Data Source
  KAKENHI-PROJECT-16K17919
[Presentation] Direct analysis of systemic insecticides in leaf using SALDI imaging mass spectrometry with sputter-deposited metal film2016
- Author(s)
  I. Osaka
- Organizer
  7th SETAC World Congress/ SETAC North America 37th Annual Meeting
- Place of Presentation
  Rosen Shingle Creek、Florida、Orlando
- Year and Date
  2016-11-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K17919
[Presentation] 合金スパッタリング法を利用した表面支援レーザー脱離イオン化による質量分析イメージング2016
- Author(s)
  加藤雄太，大坂一生，川崎英也，荒川隆一
- Organizer
  第64回質量分析総合討論会
- Place of Presentation
  ホテル阪急エキスポパーク、大阪府、吹田市
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-16K17919
[Presentation] 質量分析イメージング法を用いた生体分子の局在解析2016
- Author(s)
  大坂一生
- Organizer
  文科省ナノテクロノジープラットフォーム　カラダを見る～全身まるごと観察～
- Place of Presentation
  科学技術振興機構(JST)東京本部別館、東京都
- Invited
- Data Source
  KAKENHI-PROJECT-16K17919
[Presentation] 薬学・農学・化学のための質量分析イメージング法2016
- Author(s)
  大坂一生
- Organizer
  文科省ナノテクロノジープラットフォーム地域セミナー in 帯広畜産大学
- Place of Presentation
  帯広畜産大学、北海道、帯広市
- Invited
- Data Source
  KAKENHI-PROJECT-16K17919
[Presentation] 有機マトリックスを共存させた表面支援レーザー脱離イオン化イメージング質量分析法によるマウス組織切片中の薬物検出2016
- Author(s)
  野崎和吉，中田直之，佐藤公也，早田錦矢，川崎英也，荒川隆一，大坂一生
- Organizer
  第64回質量分析総合討論会
- Place of Presentation
  ホテル阪急エキスポパーク、大阪府、吹田市
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-16K17919
[Presentation] エレクトロスプレーイオン化法における化合物の物性とイオン収量の関係の評価2014
- Author(s)
  大坂一生
- Organizer
  日本分析化学会高分子分析研究懇談会第375回例会
- Place of Presentation
  ゆうぽうと(東京都品川区)
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PROJECT-24619006
[Presentation] 高感度プロテオーム解析のためのLC/MSにおけるペプチドのイオン収量の評価,物質構造解析2014
- Author(s)
  大坂一生
- Organizer
  理研シンポジウム物質構造解析2014 MSとNMRの基礎と実践
- Place of Presentation
  鈴木梅太郎記念ホール(埼玉県和光市)
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-24619006
[Presentation] 高感度プロテオーム解析のためのLC/MSにおけるペプチドのイオン収量の評価2014
- Author(s)
  大坂一生
- Organizer
  理研シンポジウム
- Place of Presentation
  理化学研究所　鈴木梅太郎記念ホール
- Invited
- Data Source
  KAKENHI-PROJECT-24619006
[Presentation] Influence of basicity and hydrophobicity of amino acid residues on the positive- and negative-ion yields of peptides in ESI-MS2013
- Author(s)
  I. Osaka
- Organizer
  日本質量分析学会第三回若手春季シンポジウム 2013
- Place of Presentation
  千里中央ライフサイエンスセンター
- Invited
- Data Source
  KAKENHI-PROJECT-24619006
[Presentation] Influence of arginine, lysine, phenylalanine residues and phosphorylation on the positive- and negative-ion yields of peptides in ESI-MS2013
- Author(s)
  Issey Osaka, Mitsuo Takayama
- Organizer
  HUPO 12th Annual world congress
- Place of Presentation
  Pacifico Yokohama
- Data Source
  KAKENHI-PROJECT-24619006
[Presentation] ESIにおけるペプチドの電荷状態分布に対する溶媒組成の影響2013
- Author(s)
  大坂一生、高山光男
- Organizer
  第61回質量分析総合討論会
- Place of Presentation
  つくば国際会議場　つくばエポカル
- Data Source
  KAKENHI-PROJECT-24619006
[Presentation] 異なる分離条件の2つのLC-MSクロマトグラムを用いた2次元マッピング．リン酸化タンパク質消化物の解析2013
- Author(s)
  上野裕美子・、大坂一生・、川崎英也、荒川隆一
- Organizer
  第61回質量分析総合討論会
- Place of Presentation
  つくば国際会議場
- Data Source
  KAKENHI-PROJECT-24619006
[Presentation] Pseudo two-dimensional chromatograms of ginsenosides in Panax ginseng root and callus2012
- Author(s)
  I. Osaka, H. Hisatomi, Y. Ueno, S. Taira, H. Kawasaki, R. Arakawa
- Organizer
  60th ASMS (the American Society for Mass Spectrometry) Conference on mass spectrometry
- Place of Presentation
  Vancouver Convention Centre
- Data Source
  KAKENHI-PROJECT-24619006
[Presentation] Mass spectrometric analysis of ginsenosides in Panax ginseng root and callus using pseudo two-dimensional liquid chromatogram2012
- Author(s)
  Y. Ueno, I. Osaka, H. Hisatomi, S. Taira, H. Kawasaki, R. Arakawa
- Organizer
  19th International Mass Spectrometry Conference
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24619006
[Presentation] Optimization of ESI method for the LC-MS analysis of phosphorylated peptide2012
- Author(s)
  I. Osaka, M. Takayama
- Organizer
  19th International Mass Spectrometry Conference
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24619006
[Presentation] More and Less Susceptible Amino Acid Residues to In-source Decay of Protein and Peptide in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry2012
- Author(s)
  M. Takayama, I. Osaka, M. Sakakura, R. Iimuro
- Organizer
  19th International Mass Spectrometry Conference
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24619006
[Presentation] 分離条件の異なる二つのLC-MSクロマトグラムを統合した2次元マッピング法の応用
- Author(s)
  大坂一生, 上野裕美子, 川崎英也, 荒川隆一
- Organizer
  第62回質量分析総合討論会
- Place of Presentation
  ホテル阪急エキスポパーク(大阪府吹田市)
- Year and Date
  2014-05-14 – 2014-05-16
- Data Source
  KAKENHI-PROJECT-24619006
[Presentation] Two dimensional mapping integrating two chromatogramsobtained with LC- MS for proteomics analysis
- Author(s)
  I. Osaka, Y. Ueno, H. Kawasaki, R. Arakawa
- Organizer
  30th International Symposium on Chromatography
- Place of Presentation
  Salzburg, Austria
- Year and Date
  2014-09-12 – 2014-09-18
- Data Source
  KAKENHI-PROJECT-24619006

1. Karashima Shigehiro (30801584)

# of Collaborated Projects: 4 results

# of Collaborated Products: 25 results
2. 南保英孝 (30322118)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. Kawasaki Hideya (50322285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. TAMURA Hiroshi (20163694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. FURUIKE Tetsuya (10360942)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 宮治裕史 (50372256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 大島吉輝 (00111302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 荒川隆一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 一柳優子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Osaka Issey 大坂 一生

OSAKA Issey 大坂 一生

Research Projects

Research Products

Co-Researchers

疾患予測と個別化医療を目指した網羅的ステロイドホルモン解析と機械学習モデルの融合

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Health predictions with hair metabolomics using ion mobility mass spectrometryPrincipal Investigator

Principal Investigator

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Elucidation of the Salt-Sensitive Metabolic Regulatory Network Mediated by Gut Microbiota-Derived Steroid Hormones

Principal Investigator

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Development of basic analytical technology for diagnosing lifestyle-related diseases derived from adrenocortical hormonesPrincipal Investigator

Principal Investigator

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多様性拡大抽出物を活用した薬理活性志向型天然化合物類縁体ライブラリーの構築

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Development of novel laser desorption ionization with metal filmPrincipal Investigator

Principal Investigator

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Novel Gold nanocluster-based Photosensitizers for Antimicrobial Photodynamic Therapy

Principal Investigator

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Study on ion yield of phosphorylated peptides in ESI for proteomic analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

[Journal Article] Normalization based on m/z shift and ion intensity in SALDI-TOFMS imaging of samples with non-horizontal surface2024

Author(s)

Journal Title

Data Source

[Journal Article] Direct detection of dithiocarbamate fungicides by SALDI/MS using porous TiC ceramic powder as substrate2024

Author(s)

Journal Title

Data Source

[Journal Article] Effect of the surface morphology of a metal film on ion yields in a platinum-film surface-assisted laser desorption/ionization mass spectrometry2024

Author(s)

Journal Title

Data Source

[Journal Article] Direct Additive Detection in Polymer Films via Platinum-Assisted SALDI Mass Spectrometry Imaging2024

Author(s)

Journal Title

Data Source

[Journal Article] Imaging analysis of phosphatidylcholines and diacylglycerols using surface-assisted laser desorption/ionization mass spectrometry with metal film formed by mist chemical vapor deposition2023

Author(s)

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Data Source

[Journal Article] Rapidity and Precision of Steroid Hormone Measurement2022

Author(s)

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DOI

Data Source

[Journal Article] Comprehensive steroid assay with non-targeted analysis using liquid chromatography ion mobility mass spectrometry2022

Author(s)

Osaka Issey 大坂一生

OSAKA Issey 大坂一生