ISHIDA Kazuya 石田和也

Researcher Number	90550509
Other IDs
Affiliation (based on the past Project Information) *help	2014: 富山大学, 大学院医学薬学研究部(薬学) 2011 – 2014: 富山大学, 大学院医学薬学研究部(薬学), 助教 2011: 富山大学, 大学院・医学薬学研究部(医学), 助教 2010 – 2011: 富山大学, 大学院・医学薬学研究部(薬学), 助教
Review Section/Research Field	Principal Investigator Medical pharmacy Except Principal Investigator Medical pharmacy
Keywords	Principal Investigator トランスポーター / カチオン性薬物 / 消化管吸収 / 臨床試験 / 薬物動態 Except Principal Investigator 薬物代謝 / 治療薬物モニタリング / シルデナフィル / 小児薬物動態 / 個別投与設計 … More / 循環器官用薬 / 薬物動態評価法 / タダラフィル / フレカイニド / 小児 / トランスポーター / 消化管吸収機構 / 腎排泄性薬剤 / ミゾリビン / バイオアベイラビリオティ / 臨床薬物動態試験 / 採血デザイン Less

カチオン性薬物の消化管吸収変動機構の解明Principal Investigator
- Principal Investigator
  
  石田和也
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Toyama
Variability of bioavailability and intestinal absorption mechanism of mizoribine and bisoprolol
- Principal Investigator
  
  HASHIMOTO Yukiya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Toyama
A simple method to evaluate pharmacokinetics in children with a reduced blood sampling and optimization of dosage of cardiovascular drugs.
- Principal Investigator
  
  TAGUCHI MASATO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Toyama
The mechanisms of the variability in the intestinal absorption of nucleoside drugsPrincipal Investigator
- Principal Investigator
  
  ISHIDA Kazuya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Toyama
Clinical pharmacokinetic trials using limited sampling design and robust data analysis
- Principal Investigator
  
  HASHIMOTO Yukiya
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Toyama

All 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Plasma concentrations of tadalafil in children with pulmonary arterial hypertension.2014
- Author(s)
  Kohno H, Ichida F, Hirono K, Ozawa S, Yoshimura N, Nakamura T, Akita C, Ishida K, and Taguchi M.
- Journal Title
  
  Ther Drug Monit.
  
  Volume: 36 Issue: 5 Pages: 576-83
- DOI
  10.1097/ftd.0000000000000055
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590182
[Journal Article] Variability of Bioavailability and Intestinal Absorption Mechanisms of Metoprolol2014
- Author(s)
  Fukao M., Ishida K., Horie A., Taguchi M., Nozawa T., Inoue H., and Hashimoto Y.
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 29 Issue: 2 Pages: 162-167
- DOI
  10.2133/dmpk.DMPK-13-RG-057
- NAID
  130004463366
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590182, KAKENHI-PROJECT-26860096
[Journal Article] Effect of chronic hypoxic hypoxia on oxidation and glucuronidation of carvedilol in rats.2014
- Author(s)
  Yamaura S., Fukao M., Ishida K., Taguchi M., and Hashimoto Y.
- Journal Title
  
  Eur. J. Metab. Pharmacokinet.
  
  Volume: 39 Issue: 1 Pages: 53-59
- DOI
  10.1007/s13318-013-0140-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590182
[Journal Article] Plasma concentrations of tadalafil in children with pulmonary arterial hypertension2014
- Author(s)
  Kohno H., Ichida F., Hirono K., Ozawa S., Yoshimura N., Nakamura T., Akita C., Ishida K., and Taguchi M.
- Journal Title
  
  Ther. Drug Monitor.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590182
[Journal Article] Pharmacokinetic variability of flecainide in younger Japanese patients and mechanisms for renal excretion and intestinal absorption.2014
- Author(s)
  Horie A., Ishida K., Taguchi M., Ozawa A., Hirono K., Ichida F., and Hashimoto Y.
- Journal Title
  
  Biopharm. Drug Dispos.
  
  Volume: 35 Issue: 3 Pages: 145-153
- DOI
  10.1002/bdd.1877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590182, KAKENHI-PROJECT-24591571
[Journal Article] Membrane transport mechanisms of choline in human intestinal epithelial LS180 cells2014
- Author(s)
  Asuka Horie, Kazuya Ishida, Yuri Watanabe, Kaito Shibata, Yukiya Hashimoto
- Journal Title
  
  Biopharmaceutics & Drug Disposition
  
  Volume: 35 Issue: 9 Pages: 532-542
- DOI
  10.1002/bdd.1917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860096
[Journal Article] Advantages and disadvantages of conditional estimation methods for population pharmacokinetic analysis of mizoribin.2014
- Author(s)
  Kazuya Ishida, Miki Fukao, Hiromichi Ith, Osamu Uemura, and Yukiya Hashimoto
- Journal Title
  
  Jpn. J. Health Care Sci.
  
  Volume: 40 Pages: 643-651
- NAID
  130005108788
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590181
[Journal Article] Effect of Salt Intake on Bioavailability of Mizoribine in Healthy Japanese Males2013
- Author(s)
  Ishida K, Fukao M, Watanabe H, Taguchi M, Miyawaki T, Matsukura H, Uemura O, Zhang Z, Unadkat JD, Hashimoto Y
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 28 Issue: 1 Pages: 75-80
- DOI
  10.2133/dmpk.DMPK-12-NT-043
- NAID
  130004463290
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790176, KAKENHI-PROJECT-24590181
[Journal Article] Variability of Bioavailability and Intestinal Absorption Characteristics of Bisoprolol2013
- Author(s)
  Kazuya Ishida
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 28 Issue: 6 Pages: 491-496
- DOI
  10.2133/dmpk.DMPK-13-RG-017
- NAID
  130004463332
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790176, KAKENHI-PROJECT-24590181
[Journal Article] Population pharmacokinetics of mizoribine in pediatric recipients of renal transplantation.2012
- Author(s)
  Ishida K, Motoyama O, Shishido S, Tsuzuki K, and Hashimoto Y
- Journal Title
  
  Clin Exp. Nephrol.
  
  Volume: (in press)
- NAID
  10031122270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590152
[Journal Article] Population pharmacokinetics of mizoribine in pediatric recipients of renal transplantation2012
- Author(s)
  Ishida, Kazuya
- Journal Title
  
  Clin.Exp.Nephrol.
  
  Volume: (In press) Issue: 5 Pages: 799-804
- DOI
  10.1007/s10157-012-0616-4
- NAID
  10031122270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590152, KAKENHI-PROJECT-23790176
[Journal Article] Effect of genetic polymorphisms of SLC28A1, ABCG2, and ABCC4 on bioavailability of mizoribine in healthy Japanese males2011
- Author(s)
  Fukao M, Ishida K, Sakamoto T, Taguchi M, Matsukura H, Miyawaki T, and Hashimoto Y
- Journal Title
  
  Drug Metab. Pharmacokinet.
  
  Volume: 26 Pages: 538-543
- NAID
  130004463218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590152
[Journal Article] Mechanisms for membrane transport of metformin in human intestinal epithelial Caco-2 cells2011
- Author(s)
  Horie A, Sakata J, Nishimura M, Ishida K, Taguchi M, and Hashimoto Y
- Journal Title
  
  Biopharm. Drug Dispos.
  
  Volume: 32 Pages: 253-260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590152
[Journal Article] Population pharmacokinetics of mizoribine in adult recipients of renal transplantation2011
- Author(s)
  Ishida, Kazuya
- Journal Title
  
  Clin.Exp.Nephrol.
  
  Volume: 15 Issue: 6 Pages: 900-906
- DOI
  10.1007/s10157-011-0487-0
- NAID
  10030341853
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590152, KAKENHI-PROJECT-23790176
[Journal Article] Population pharmacokinetics of mizoribine in adult recipients of renal transplantation.2011
- Author(s)
  Ishida K, Okamoto M, Ishibashi M, and Hashimoto Y
- Journal Title
  
  Clin Exp. Nephrol.
  
  Volume: 15 Pages: 900-906
- NAID
  10030341853
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590152
[Journal Article] Effect of Genetic Polymorphisms of SLC28A1, ABCG2, and ABCC4 on Bioavailability of Mizoribine in Healthy Japanese Males2011
- Author(s)
  Fukao, Miki
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 26 Issue: 5 Pages: 538-543
- DOI
  10.2133/dmpk.DMPK-11-NT-040
- NAID
  130004463218
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590152, KAKENHI-PROJECT-23790176
[Journal Article] Mechanisms responsible for the different uptakes of mizoribine and ribavirin in human epithelial LS180 cells.2010
- Author(s)
  Ishida, Kazuya
- Journal Title
  
  Jpn.J.Pharm.Health Care Sci.
  
  Volume: 36 Pages: 900-905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590152
[Journal Article] Inhibitory and stimulative effects of amiodarone on metabolism of carvedilol in human liver microsomes2010
- Author(s)
  Horiuchi I, Kato Y, Nakamura A, Ishida K, Taguchi M, and Hashimoto Y
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 33 Pages: 717-720
- NAID
  130000248026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590152
[Journal Article] Membrane transport mechanisms of quinidine and procainamide in renal LLC-PK_1 and intestinal LS180 cells2010
- Author(s)
  Masago M, Takaai M, Sakata J, Horie A, Ito T, Ishida K, Taguchi M, and Hashimoto Y
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 33 Pages: 1407-1412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590152
[Journal Article] A simulation study to evaluate limited sampling strategies to estimate area under the curve of drug concentration versus time following repetitive oral dosing : limited sampling model versus naive trapezoidal method2009
- Author(s)
  Kayano Y, Horiuchi I, Mori YI, Ishida K, Saito T, Taguchi M, and Hashimoto Y
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 32 Pages: 1486-1490
- NAID
  130000117270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590152
[Journal Article] Involvement of the CYPIA subfamily in stereoselective metabolism of carvedilol in β-naphthoflavone-treated Caco-2 cells.2009
- Author(s)
  Ishida, Kazuya
- Journal Title
  
  Biol.Pharm.Bull. 32
  
  Pages: 513-516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590152
[Journal Article] Temperature-dependent specific transport of levofloxacin in human intestinal epithelial LS180 cells2009
- Author(s)
  Fukumori S, Masago M, Ishida K, Kayano Y, Taguchi M, and Hashimoto Y
- Journal Title
  
  Biopharm. Drug Dispos.
  
  Volume: 30 Pages: 448-456
- NAID
  120002463535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590152
[Journal Article] Membrane transport mechanisms of mizoribine in the rat intestine and human epithelial LS180 cells2009
- Author(s)
  Ishida K, Takaai M, Yotsutani A, Taguchi M, and Hashimoto Y
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 32 Pages: 741-745
- NAID
  110007160665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590152
[Journal Article] Involvement of the CYP1A subfamily in stereoselective metabolism of carvedilol inβ-naphthoflavone-treated Caco-2 cells2009
- Author(s)
  Ishida K, Taguchi M, Akao T, and Hashimoto Y
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 32 Pages: 513-516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] タダラフィルの脱メチレン代謝に関与するP450分子種の速度論的評価2014
- Author(s)
  田口雅登，高広理佳子，中村早稀，河野寛之，石田和也，秋田千里，中村常之，芳村直樹，小澤綾佳，廣野恵一，市田蕗子
- Organizer
  第20回日本小児肺循環研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590182
[Presentation] タダラフィルの脱メチレン代謝に関与するCYP分子種の速度論的評価2014
- Author(s)
  高広理佳子，田口雅登，中村早稀，河野寛之，石田和也，秋田千里，中村常之，芳村直樹，小澤綾佳，廣野恵一，市田蕗子
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24590182
[Presentation] Variability of bioavailability and intestinal absorption characteristics of bisoprolol2013
- Author(s)
  Ishida K, Horie A, Nishimura M, Taguchi M, Fujii N, Nozawa T, Inoue H, Hashimoto Y
- Organizer
  第7回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23790176
[Presentation] Variability of bioavailability of mizoribine in healthy males and mechanisms of barrier function for intestinal absorption.2013
- Author(s)
  Kazuya Ishida
- Organizer
  日本薬物動態学会第28回年会
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-23790176
[Presentation] 経口肺血管拡張薬タダラフィルの小児における体内動態2013
- Author(s)
  田口雅登，河野寛之，高広理佳子，石田和也，秋田千里，中村常之，芳村直樹，小澤綾佳，廣野恵一，市田蕗子
- Organizer
  日本医療薬学会第23回年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24590182
[Presentation] Variability of bioavailability of mizoribine in healthy males and mechanisms of barrier function for intestinal absorption2013
- Author(s)
  Kazuya Ishida
- Organizer
  日本薬物動態学会第28回年会
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-24590181
[Presentation] Variability of bioavailability and intestinal absorption characteristics of bisoprolol2013
- Author(s)
  Kazuya Ishida
- Organizer
  第7回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  東北大学片平キャンパスさくらホール（宮城県）
- Data Source
  KAKENHI-PROJECT-23790176
[Presentation] 小児肺高血圧症患者におけるタダラフィルの体内動態解析2013
- Author(s)
  河野寛之，高広理佳子，石田和也，田口雅登，秋田千里，中村常之，芳村直樹，廣野恵一，市田蕗子
- Organizer
  第21回医療薬学フォーラム
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-24590182
[Presentation] Variability of bioavailability and intestinal absorption characteristics of bisoprolol2013
- Author(s)
  Kazuya Ishida
- Organizer
  第7回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  東北大学片平キャンパスさくらホール(宮城県）
- Data Source
  KAKENHI-PROJECT-24590181
[Presentation] Variability of bioavailability of mizoribine in healthy males and mechanisms of barrier function for intestinal absorption2013
- Author(s)
  Ishida K, Fukao M, Takabayashi M, Taguchi M, Itoh H, Hashimoto Y
- Organizer
  日本薬物動態学会第28回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790176
[Presentation] Improvement of the intestinal absorption of mizoribine by salt intake in healthy Japanese males2012
- Author(s)
  Fukao M, Ishida K, Watanabe H, Taguchi M, Miyawaki T, Matsukura H, Uemura O, Zhang Z, Unadkat JD, Hashimoto Y
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790176
[Presentation] Effect of salt intake on bioavailability of mizoribine in healthy Japanese males2012
- Author(s)
  Kazuya Ishida
- Organizer
  18th North American ISSX meeting
- Place of Presentation
  Hilton Anatole Dallas Hotel, Dallas, Texas, USA
- Data Source
  KAKENHI-PROJECT-24590181
[Presentation] Effect of salt intake on bioavailability of mizoribine in healthy Japanese males2012
- Author(s)
  Ishida K, Fukao M, Watanabe H, Taguchi M, Miyawaki T, Matsukura H, Uemura O, Zhang Z, Unadkat JD, Hashimoto Y
- Organizer
  18^<th> North American ISSX meeting
- Place of Presentation
  Dallas
- Data Source
  KAKENHI-PROJECT-23790176
[Presentation] Zhang Z, Unadkat JD,橋本征也,ミゾリビンの吸収に及ぼすナトリウムの影響2012
- Author(s)
  渡邉ひとみ,石田和也,深尾美紀,田口雅登,宮脇利男,松倉裕喜,上村治
- Organizer
  日本薬学会北陸支部第124回例会
- Place of Presentation
  富山
- Year and Date
  2012-11-18
- Data Source
  KAKENHI-PROJECT-23790176
[Presentation] カルベジロールの酸化・抱合代謝に及ぼす低酸素暴露の影響2012
- Author(s)
  田口雅登、深尾美紀、山浦静、石田和也、橋本征也
- Organizer
  第22回日本医療薬学会年会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-24590182
[Presentation] Effect of salt intake on bioavailability of mizoribine in healthy Japanese males2012
- Author(s)
  Kazuya Ishida
- Organizer
  18th North American ISSX meeting
- Place of Presentation
  Hilton Anatole Dallas Hotel, Dallas, Texas, USA
- Data Source
  KAKENHI-PROJECT-23790176
[Presentation] Effect of genetic polymorphisms of SLC28A1, ABCG2, and ABCC4 on bioavailability of mizoribine in healthy Japanese males2011
- Author(s)
  Kazuya Ishida
- Organizer
  2011 AAPS Annual Meeting and Exposition
- Place of Presentation
  Walter E. Washington Convention Center, Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-23790176
[Presentation] Effect of genetic polymorphisms of SLC28A1, ABCG2, and ABCC4 on bioavailability of mizoribine in healthy Japanese males2011
- Author(s)
  Ishida, Kazuya
- Organizer
  2011 AAPS Annual Meeting and Exposition
- Place of Presentation
  Walter E.Washington Convention Center, Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] Effect of genetic polymorphisms of nucleoside and efflux transporters on bioavailability of mizoribine2011
- Author(s)
  Fukao M, Ishida K, Taguchi M, Matsukura H, Miyawaki T, and Hashimoto Y
- Organizer
  日本薬物動態学会第26年会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] 培養ヒト腸上皮Caco-2細胞におけるメトホルミンの膜輸送機構2011
- Author(s)
  堀江明日佳,西邑麻希,石田和也,坂田淳平,田口雅登,橋本征也
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] 培養ヒト腸上皮細胞を用いたミゾリビンの消化管吸収機構解析2011
- Author(s)
  横田篤,森川真圭,石田和也,田口雅登,橋本征也
- Organizer
  日本薬学会北陸支部第123回例会
- Place of Presentation
  金沢
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] Effect of genetic polymorphisms of nucleoside and efflux transporters on bioavailability of mizoribine2011
- Author(s)
  Fukao M, Ishida K, Taguchi M, Matsukura H, Miyawaki T, and Hashimoto Y
- Organizer
  日本薬物動態学会第26年会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23790176
[Presentation] 健常成人のミゾリビンの消化管吸収に対する遺伝と食塩摂取の影響2011
- Author(s)
  深尾美紀,渡邉ひとみ,石田和也,田口雅登,橋本征也,松倉裕喜,宮脇利男
- Organizer
  日本薬学会北陸支部第123回例会
- Place of Presentation
  金沢
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-23790176
[Presentation] 培養ヒト腸上皮細胞を用いたミゾリビンの消化管吸収機構解析2011
- Author(s)
  横田篤,森川真圭,石田和也,田口雅登,橋本征也
- Organizer
  日本薬学会北陸支部第123回例会
- Place of Presentation
  金沢
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-23790176
[Presentation] Effect of Genetic Polymorphisms of SLC28A1, ABCG2, and ABCC4 on Bioavailability of Mizoribine in Healthy Japanese Males2011
- Author(s)
  Ishida K, Fukao M, Watanabe H, Taguchi M, Matsukura H, Miyawaki T, and Hashimoto Y
- Organizer
  2011 American Association of Pharmaceutical Scientists Annual Meeting
- Place of Presentation
  Washington, D.C.
- Data Source
  KAKENHI-PROJECT-23790176
[Presentation] 健常成人のミゾリビンの消化管吸収に対する遺伝と食塩摂取の影響2011
- Author(s)
  深尾美紀,渡邉ひとみ,石田和也,田口雅登,橋本征也,松倉裕喜,宮脇利男
- Organizer
  日本薬学会北陸支部第123回例会
- Place of Presentation
  金沢
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] Effect of Genetic Polymorphisms of SLC28A1, ABCG2, and ABCC4 on Bioavailability of Mizoribine in Healthy Japanese Males2011
- Author(s)
  Ishida K, Fukao M, Watanabe H, Taguchi M, Matsukura H, Miyawaki T, and Hashimoto Y
- Organizer
  2011 American Association of Pharmaceutical Scientists Annual Meeting
- Place of Presentation
  Washington, D. C.
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] Optimal limited sampling designs to estimate maximal concentration and area under the curve of mizoribine in pediatric patients with renal disease2010
- Author(s)
  Ishida K, Takaai M, Uemura O, Nagai T, Satomura K, Kaneda H, Ohta K, Fujieda M, Wada N, Goto Y, Morooka M, and Hashimoto Y
- Organizer
  Pharmaceutical Sciences World Congress 2010
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] Inhibitory and stimulative effects of amiodarone on stereoselective metabolism of carvedilol in human and rat liver microsomes2010
- Author(s)
  Horiuchi I, Kato Y, Nakamura A, Ishida K, Taguchi M, and Hashimoto Y
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] 腎上皮LLC-PK_1および腸上皮LS180細胞におけるプロカインアミドの膜輸送機構解析2010
- Author(s)
  真砂美希,坂田淳平,西條早紀,鷹合麻里,堀江明日佳,伊藤俊和,石田和也,田口雅登,橋本征也
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] 小児腎疾患患者におけるミゾリビンの最適少数採血デザインの評価2010
- Author(s)
  石田和也,鷹合麻里,上村治,永井琢人,里村憲一,金田尚,太田和秀,藤枝幹也,和田尚弘,後藤芳充,諸岡正史,橋本征也
- Organizer
  医療薬学フォーラム2010
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] 小児腎疾患患者におけるミゾリビンのAUCとC_<max>予測のための最適少数採血デザインの評価2010
- Author(s)
  石田和也,鷹合麻里,上村治,永井琢人,里村憲一,金田尚,太田和秀,藤枝幹也,和田尚弘,後藤芳充,諸岡正史,橋本征也
- Organizer
  第45回日本小児腎臓病学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] 腸上皮LS180細胞を用いたプロカインアミドの膜輸送特性解析2010
- Author(s)
  石田和也,真砂美希,坂田淳平,鷹合麻里,堀江明日佳,伊藤俊和,田口雅登、橋本征也
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] Caco-2細胞におけるカルベジロールの立体選択的代謝機構2009
- Author(s)
  石田和也,田口雅登,赤尾光昭,橋本征也
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] 培養ヒト腸上皮Caco-2におけるメトトレキサートの経細胞輸送機構2009
- Author(s)
  鷹合麻里,坂田淳平,石田和也,田口雅登,橋本征也
- Organizer
  日本薬学会北陸支部第120回例会
- Place of Presentation
  金沢
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] カルベジロールの立体選択的代謝に及ぼすアミオダロンの影響2009
- Author(s)
  堀内威佐男,加藤悠也,中村有沙,石田和也,田口雅登,橋本征也
- Organizer
  第30回臨床薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] ラット小腸および培養ヒト腸上皮LS180細胞におけるミゾリビン膜輸送の特性解析2009
- Author(s)
  鷹合麻里,石田和也,四谷綾乃,田口雅登,橋本征也
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] Limited sampling modelによる薬物連投時のAUC推定に対するシミュレーション評価2009
- Author(s)
  堀内威佐男,森ゆんい,石田和也,萱野勇一郎,田口雅登,橋本征也
- Organizer
  第26回日本TDM学会・学術大会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] ミゾリビンのバイオアベイラビリティの個体間変動機構2009
- Author(s)
  四谷綾乃,鷹合麻里,坂本卓也,横田篤,堀内威佐男,石田和也,田口雅登,橋本征也,松倉裕喜
- Organizer
  第30回臨床薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] LS180細胞を用いたミゾリビン小腸吸収の変動機構解析2009
- Author(s)
  四谷綾乃,鷹合麻里,坂本卓也,横田篤,堀内威佐男,石田和也,田口雅登,松倉裕喜,橋本征也
- Organizer
  日本薬学会北陸支部第121回例会
- Place of Presentation
  富山
- Year and Date
  2009-12-06
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] 薬物連投時のAUC推定におけるLimited Sampling Modelの精度評価2009
- Author(s)
  堀内威佐男,森ゆんい,石田和也,萱野勇一郎,田口雅登,橋本征也
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] Absorption mechanisms of mizoribine and ribavirin in rat intestine and human epithelial LS180 cells2009
- Author(s)
  Ishida K, Yotsutani A, Sakamoto T, Takaai M, Taguchi M, and Hashimoto Y
- Organizer
  日本薬物動態学会第24回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] 連投薬物のAUC推定におけるLimited sampling modelの有用性評価2009
- Author(s)
  田口雅登,堀内威佐男,森ゆんい,萱野勇一郎,石田和也,橋本征也
- Organizer
  医療薬学フォーラム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590152
[Presentation] Membrane transport mechanisms of choline in human intestinal epithelial LS180 cells
- Author(s)
  Kazuya Ishida, Asuka Horie, Yuri Watanabe, Kaito Shibata, Yukiya Hashimoto
- Organizer
  19th North American ISSX/29th JSSX Meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-26860096
[Presentation] 小腸H+／三級アミン対向輸送系の活性における基質の脂溶性および極性表面積重要性
- Author(s)
  深尾美紀、石田和也、松葉映美、渡邉柚梨、堀江明日佳、橋本征也
- Organizer
  日本薬学会第１３５年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590181

1. HASHIMOTO Yukiya (90228429)

# of Collaborated Projects: 2 results

# of Collaborated Products: 33 results
2. NOZAWA Takashi (00180737)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. ICHIDA Fukiko (30223100)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. TAGUCHI Masato (20324056)

# of Collaborated Projects: 2 results

# of Collaborated Products: 35 results
5. SAITO Kazuyoshi (30566097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HIRONO Keiichi (80456384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

ISHIDA Kazuya 石田 和也

Research Projects

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Co-Researchers

カチオン性薬物の消化管吸収変動機構の解明Principal Investigator

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Variability of bioavailability and intestinal absorption mechanism of mizoribine and bisoprolol

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A simple method to evaluate pharmacokinetics in children with a reduced blood sampling and optimization of dosage of cardiovascular drugs.

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The mechanisms of the variability in the intestinal absorption of nucleoside drugsPrincipal Investigator

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Clinical pharmacokinetic trials using limited sampling design and robust data analysis

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[Journal Article] Plasma concentrations of tadalafil in children with pulmonary arterial hypertension.2014

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[Journal Article] Variability of Bioavailability and Intestinal Absorption Mechanisms of Metoprolol2014

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[Journal Article] Effect of chronic hypoxic hypoxia on oxidation and glucuronidation of carvedilol in rats.2014

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[Journal Article] Plasma concentrations of tadalafil in children with pulmonary arterial hypertension2014

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[Journal Article] Pharmacokinetic variability of flecainide in younger Japanese patients and mechanisms for renal excretion and intestinal absorption.2014

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[Journal Article] Membrane transport mechanisms of choline in human intestinal epithelial LS180 cells2014

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[Journal Article] Advantages and disadvantages of conditional estimation methods for population pharmacokinetic analysis of mizoribin.2014

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[Journal Article] Effect of Salt Intake on Bioavailability of Mizoribine in Healthy Japanese Males2013

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[Journal Article] Variability of Bioavailability and Intestinal Absorption Characteristics of Bisoprolol2013

ISHIDA Kazuya 石田和也