Taniguchi Hiroaki 谷口博昭

… Alternative Names

TANIGUCHI Hiroaki 谷口博昭

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Researcher Number	90563289
Other IDs	https://orcid.org/0000-0003-0494-5290
Affiliation (Current)	2024: 慶應義塾大学, 医学部(信濃町), 特任准教授 2024: 金沢大学, がん進展制御研究所, 教授
Affiliation (based on the past Project Information) *help	2024: 慶應義塾大学, 医学部(信濃町), 特任准教授 2018: 東京大学, 医科学研究所, 特任研究員 2015 – 2017: 東京大学, 医科学研究所, 特任准教授 2011 – 2013: 東京大学, 医科学研究所, 特任准教授 2011: 東京大学, 医科学研究所, 特任助教
Review Section/Research Field	Principal Investigator Tumor therapeutics / Tumor biology Except Principal Investigator Tumor diagnosis / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Tumor therapeutics
Keywords	Principal Investigator トランスレーショナルリサーチ / 癌 / 遺伝子 / 蛋白質 / 薬学 / タンパク質 / 創薬スクリーニング系 / タンパク質相互作用 / がん幹細胞性 / 癌幹細胞 … More / KLF2遺伝子 / EZH2遺伝子 / ヒストンメチル化酵素 / 発生・分化 / 幹細胞 … More Except Principal Investigator 臨床 / 癌 / がん / 転移 / 多分子制御 / 核酸医療 / DDS / ウイルスベクター / 癌幹細胞 / 分子標的薬 / 癌治療 / 遺伝子治療 / 遺伝子 / がん幹細胞 / 腫瘍マーカー / マクロアレイ / マイクロアレイ / トランスレーショナルリサーチ / ゲノム / マイクロＲＮＡ / バイオマーカー / ＤＮＡメチル化 / エピゲノム / 肝癌 / 大腸癌 / 胃癌 Less

多分子標的型核酸と高性能化DDSによって転移性癌をリセットするムーンショット計画
- Principal Investigator
  
  山本浩文
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Osaka University
Functional analysis and development for anti-tumor compounds targeted PRDM14 relating to cancer stemness based on protein-protein interactionPrincipal Investigator
- Principal Investigator
  
  Taniguchi Hiroaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  The University of Tokyo
The development of gene therapy for breast cancer using targeted measles virus vectors
- Principal Investigator
  
  Matsumura Yumiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kyushu University
Identification of specific cancer stem cell markers for diagnosis
- Principal Investigator
  
  IMAI Kohzoh
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor diagnosis
- Research Institution
  The University of Tokyo
Development of novel gastrointestinal cancer diagnostic system based on large epige-nome analysis.
- Principal Investigator
  
  IMAI Kohzoh
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Tumor diagnosis
- Research Institution
  The University of Tokyo
Identification of regulatory system for cancer stemness and pplication to cancer therapeutics.Principal Investigator
- Principal Investigator
  
  TANIGUCHI Hiroaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo

All 2018 2017 2016 2014 2013 2012 2011

All Journal Article Presentation Book

[Book] 固形がんの免疫・抗体療法-基礎研究の進歩と臨床応用-抗体療法の基礎(種類、特徴など)概論日本臨床 70 巻 12 号2012
- Author(s)
  谷口博昭、今井浩三
- Data Source
  KAKENHI-PROJECT-23701063
[Book] 分子標的薬-がんから他疾患までの治癒をめざして-分子標的薬の作用機序・薬理作用- がん浸潤とその抑制日本臨床増刊号2012
- Author(s)
  星野大輔、谷口博昭、越川直彦
- Data Source
  KAKENHI-PROJECT-23701063
[Book] DDS を利用した抗体医薬の展望ドラッグデリバリーシステムの新展開 II - 核酸医薬・抗体医薬・ワクチン医療を支える DDS 技術-2012
- Author(s)
  谷口博昭、今井浩三
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-23701063
[Journal Article] PRDM14, a Zinc Finger Protein, Regulates Cancer Stemness2018
- Author(s)
  Taniguchi Hiroaki, Imai Kohzoh.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1867 Pages: 3-13
- DOI
  10.1007/978-1-4939-8799-3_1
- ISBN
  9781493987986, 9781493987993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04710
[Journal Article] PRDM14 is overexpressed in chronic pancreatitis prior to pancreatic cancer.2018
- Author(s)
  Chiharu Moriya, Kohzoh Imai, Taniguchi Hiroaki.
- Journal Title
  
  FEBS Open Bio
  
  Volume: 8(10) Issue: 10 Pages: 1733-1741
- DOI
  10.1002/2211-5463.12519
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04710
[Journal Article] PRDM14 directly interacts with heat shock proteins HSP90α and glucose-regulated protein 78.2018
- Author(s)
  Moriya C, Taniguchi H, Nagatoishi S, Igarashi H, Tsumoto K, Imai K
- Journal Title
  
  Cancer Sci.
  
  Volume: 109 Issue: 2 Pages: 373-383
- DOI
  10.1111/cas.13458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710
[Journal Article] Inhibition of PRDM14 expression in pancreatic cancer suppresses cancer stem-like properties and liver metastasis in mice2017
- Author(s)
  C. Moriya, H. Taniguchi, K. Miyata, N. Nishiyama, K. Kataoka, K. Imai
- Journal Title
  
  Carcinogenesis
  
  Volume: 38 Issue: 6 Pages: 638-648
- DOI
  10.1093/carcin/bgx040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297, KAKENHI-PROJECT-17H02098
[Journal Article] Silencing PRDM14 expression by an innovative RNAi therapy inhibits stemness, tumorigenicity, and metastasis of breast cancer2017
- Author(s)
  H. Taniguchi, D. Hoshino, C. Moriya, H. Zembutsu, N. Nishiyama, H. Yamamoto, K. Kataoka, K. Imai
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 29 Pages: 46856-46874
- DOI
  10.18632/oncotarget.16776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104
[Journal Article] Cancer Stem Cells in Human Gastrointestinal Cancer.2016
- Author(s)
  Taniguchi H, Moriya C, Igarashi H, Saitoh A, Yamamoto H, Adachi Y, Imai K.
- Journal Title
  
  Cancer Sci
  
  Volume: 107 Issue: 11 Pages: 1556-1562
- DOI
  10.1111/cas.13069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297
[Journal Article] The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma2014
- Author(s)
  Adachi Y, Ohashi H, Imsumran A, Yamamoto H, Matsunaga Y, Taniguchi H, Nosho K, Suzuki H, Sasaki Y, Arimura Y, Carbone DP, Imai K, Shinomura Y
- Journal Title
  
  Tumour Biol
  
  Volume: 35 Issue: 2 Pages: 973-985
- DOI
  10.1007/s13277-013-1131-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-24650632, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
[Journal Article] Cancer detection by ubiquitin carboxyl-terminal esterase L1 methylation in pancreatobiliary fluids2013
- Author(s)
  Kato N, Yamamoto H, Adachi Y, Ohashi H, Taniguchi H, Suzuki H, Nakazawa M, Kaneto H, Sasaki S, Imai K, Shinomura Y
- Journal Title
  
  World J Gastroenterol
  
  Volume: 19(11) Issue: 11 Pages: 1718-1727
- DOI
  10.3748/wjg.v19.i11.1718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23659400, KAKENHI-PROJECT-24650632
[Journal Article] Insulin-like growth factor receptor expression is associated with aggressive phenotypes and has therapeutic activity in biliary tract cancers.2012
- Author(s)
  Ohashi H
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Issue: 2 Pages: 252-261
- DOI
  10.1111/j.1349-7006.2011.02138.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590703, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23659401, KAKENHI-PROJECT-23701063
[Journal Article] Silencing of theKruppel-like factor 2 by the histone methyltransferase EZH2 in human cancer2012
- Author(s)
  Taniguchi H, Jacinto F.V., Villanueva A, Fernandez AF, Yamamoto H, Carmona F.J, Puertas S, Marquez VE, Shinomura Y, Imai K, and Esteller M.
- Journal Title
  
  Oncogene
  
  Volume: 31 Pages: 1988-1994
- Data Source
  KAKENHI-PROJECT-23701063
[Journal Article] Silencing of the Kruppel-like factor 2 by the histone methyltransferase EZH2 in human cancer2012
- Author(s)
  Taniguchi H, Jacinto F.V., Villanueva A, Fernandez AF, Yamamoto H, Carmona F.J, Puertas S, Marquez VE, Shinomura Y, Imai K, and Esteller M
- Journal Title
  
  Oncogene
  
  Volume: 31 Issue: 15 Pages: 1988-1994
- DOI
  10.1038/onc.2011.387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23701063, KAKENHI-PROJECT-24650632
[Journal Article] Shinomura Y. The Efficacy ofIGF-I Receptor Monoclonal Antibody against Human Gastrointestinal Carcinomas is Independent of k-ras Mutation Status.2011
- Author(s)
  Ii M, Li H, Adachi Y, Yamamoto H, Ohashi H, Taniguchi H, Arimura Y, Carbone DP, Imai K
- Journal Title
  
  Clin Cancer Res
  
  Volume: 17 Pages: 5048-5059
- Data Source
  KAKENHI-PROJECT-23701063
[Journal Article] Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis2011
- Author(s)
  Hizaki K, Yamamoto H, Taniguchi H, Adachi Y, Nakazawa M, Tanuma T, Kato N, Sukawa Y, Sanchez JV, Suzuki H, Sasaki S, Imai K, Shinomura Y
- Journal Title
  
  Mod Pathol
  
  Volume: 24 Issue: 6 Pages: 876-884
- DOI
  10.1038/modpathol.2011.10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23659400
[Journal Article] Co-expression of laminin β3 and γ2 chains and epigenetic inactivation of laminin α3 chain in gastric cancer2011
- Author(s)
  Ii M, Yamamoto H, Taniguchi H, Adachi Y, Nakazawa M, Ohashi H, Tanuma T, Sukawa Y, Suzuki H, Sasaki S, Imai K, Shinomura Y
- Journal Title
  
  Int J Oncol
  
  Volume: 39 Pages: 593-599
- Data Source
  KAKENHI-PROJECT-23240129
[Journal Article] A DNA methylation fingerprint of 1628 human samples2011
- Author(s)
  Fernandez AF, Assenov Y, Martin-Subero JI, Balint B, Siebert R, Taniguchi H, Yamamoto H, Hidalgo M, Tan AC, Galm O, Ferrer I, Sanchez-Cespedes M, Villanueva A, Carmona J, Sanchez-Mut JV, Berdasco M, Moreno V, Capella G, Monk D, Ballestar E, Ropero S, Martinez R, Sanchez-Carbayo M, Prosper F, Agirre X, Fraga MF, Grana O, Perez-Jurado L, Mora J, Puig S, Prat J, Badimon L, Puca AA, Meltzer SJ, Lengauer T, Bridgewater J, Bock C, Esteller M
- Journal Title
  
  Genome Res
  
  Volume: 22(2) Issue: 2 Pages: 407-19
- DOI
  10.1101/gr.119867.110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23701063, KAKENHI-PROJECT-24650632
[Journal Article] Shinomura Y . Co-expression of laminin ss3 and γ2 chains and epigenetic inactivationof laminin α3 chain in gastric cancer2011
- Author(s)
  Ii M, Yamamoto H, Taniguchi H, Adachi Y, Nakazawa M, Ohashi H, Tanuma T,Sukawa Y, Suzuki H, Sasaki S, Imai K
- Journal Title
  
  Int J Oncol
  
  Volume: 39 Pages: 593-599
- Data Source
  KAKENHI-PROJECT-23701063
[Journal Article] Shinomura Y. Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis2011
- Author(s)
  Hizaki K, Yamamoto H, Taniguchi H, Adachi Y, Nakazawa M, Tanuma T, Kato N, Sukawa Y, Sanchez JV, Suzuki H, Sasaki S, Imai K
- Journal Title
  
  Mod Pathol
  
  Volume: 24 Pages: 876-884
- Data Source
  KAKENHI-PROJECT-23701063
[Journal Article] Sanchez-Cespedes M, Villanueva A, Carmona J, Sanchez-Mut JV, Berdasco M, Moreno V, Capella G, Monk D, Ballestar E, Ropero S, Martinez R, Sanchez-Carbayo M, Prosper F, Agirre X, Fraga MF, Grana O, Perez-Jurado L, Mora J, Puig S, Prat J, Badimon L, Puca AA, Meltzer SJ, Lengauer T, Bridgewater J,Bock C, Esteller M. A DNA methylation fingerprint of 1628 human samples2011
- Author(s)
  Fernandez AF, Assenov Y, Martin-SuberoJI, Balint B, Siebert R, Taniguchi H, Yamamoto H, Hidalgo M, Tan AC, Galm O, Ferrer I
- Journal Title
  
  Genome Res
  
  Volume: 22(2) Pages: 407-19
- Data Source
  KAKENHI-PROJECT-23701063
[Journal Article] Insulin-like growth factor receptor expression is associated with aggressive phenotypes and has therapeuticactivity in biliary tract cancers.2011
- Author(s)
  Ohashi H, Adachi Y, Yamamoto H, Taniguchi H, Nosho K, Suzuki H, Arimura Y, Imai K, Carbone DP, Shinomura Y.
- Journal Title
  
  Cancer Sci
  
  Volume: 103(2) Pages: 252-61
- Data Source
  KAKENHI-PROJECT-23701063
[Journal Article] The efficacy of IGF-I receptor monoclonal antibody against human gastrointestinal carcinomas is independent of k-ras mutation status2011
- Author(s)
  Ii M, Li H, Adachi Y, Yamamoto H, Ohashi H, Taniguchi H, Arimura Y, Carbone DP, Imai K, Shinomura Y
- Journal Title
  
  Clin Cancer Res
  
  Volume: 17 Issue: 15 Pages: 5048-5059
- DOI
  10.1158/1078-0432.ccr-10-3131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240129
[Presentation] 革新的ナノマシンとキメラ型siRNAによる悪性腫瘍治療法: 基礎研究から研究開発まで2018
- Author(s)
  谷口博昭
- Organizer
  第27回日本がん転移学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-16H04710
[Presentation] 転写調節因子PRDM14の天然変性領域とEED間における物理化学的相互作用解析2018
- Author(s)
  大西亮輔、長門石曉、谷口博昭、津本浩平
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H04710
[Presentation] PRDM14 silencing by siRNA combined with an innovative nanoparticle reduced breast tumor formation and metastasis in vivo.2018
- Author(s)
  Taniguchi H, Moriya C, Akinaga S, Kataoka K, and Imai K.
- Organizer
  AACR Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04710
[Presentation] 乳がん細胞株においてPRDM14はヒートショック蛋白HSP90αとGRP78と直接的に相互作用する2018
- Author(s)
  谷口博昭、森谷千春、今井浩三
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H04710
[Presentation] 膵臓がんの癌幹細胞様形質を調節するPRDM14は慢性膵炎によって発現誘導される2017
- Author(s)
  森谷千春、谷口博昭、今井浩三
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H04710
[Presentation] 遺伝子改変マウスによる転写因子Prdm14の分子標的としての有効性評価2017
- Author(s)
  谷口博昭、森谷千春、山本博幸、今井浩三
- Organizer
  第26回日本がん転移学術集会・総会
- Data Source
  KAKENHI-PROJECT-16H04710
[Presentation] 乳がん細胞株におけるPRDM14分子による遺伝子発現のエピジェネテックな制御2017
- Author(s)
  谷口博昭、森谷千春、山本博幸、今井浩三
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H04710
[Presentation] 癌幹細胞様形質に関わるPRDM14を標的としたsiRNA投与によるすい臓癌細胞株の皮下腫瘍・肝転移抑制効果2017
- Author(s)
  森谷千春、谷口博昭、今井浩三
- Organizer
  第26回日本がん転移学術集会・総会
- Data Source
  KAKENHI-PROJECT-16H04710
[Presentation] PRDM14発現抑制による乳腺腫瘍の形成・転移の抑制とPRDM14新規腫瘍マーカーとしての可能性2016
- Author(s)
  谷口博昭、森谷千春、山本博幸、今井浩三
- Organizer
  第75回　日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16H04710
[Presentation] 転写因子Xは大腸癌の幹細胞性を誘導し悪質形質を促進する2016
- Author(s)
  五十嵐央祥、谷口博昭、森谷千春、斎藤杏里
- Organizer
  第75回　日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16H04710
[Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得とその臨床応用2013
- Author(s)
  谷口博昭、山本博幸、伊東文生、今井浩三
- Organizer
  第33回日本分子腫瘍マーカー研究会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23240129
[Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得2013
- Author(s)
  谷口博昭、山本博幸、越川直彦、清木元治、今井浩三
- Organizer
  第22回日本がん転移学会学術集会
- Place of Presentation
  松本市
- Year and Date
  2013-07-11
- Data Source
  KAKENHI-PROJECT-23240129
[Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得2013
- Author(s)
  谷口博昭、山本博幸、今井浩三
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2013-10-04
- Data Source
  KAKENHI-PROJECT-24650632
[Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得2013
- Author(s)
  谷口博昭、山本博幸、越川直彦、清木元治、今井浩三
- Organizer
  第22回日本がん転移学会学術集会
- Place of Presentation
  ホテルブエナビスタ松本
- Data Source
  KAKENHI-PROJECT-23240129
[Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得2013
- Author(s)
  谷口博昭、山本博幸、今井浩三
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23240129
[Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得2013
- Author(s)
  谷口博昭、山本博幸、越川直彦、清木元治、今井浩三
- Organizer
  第22回日本がん転移学会学術集会
- Place of Presentation
  ホテルブエナビスタ松本(長野県松本市)
- Year and Date
  2013-07-11
- Data Source
  KAKENHI-PROJECT-24650632
[Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得とその臨床応用2013
- Author(s)
  谷口博昭、山本博幸、伊東文生、今井浩三
- Organizer
  第33回日本分子腫瘍マーカー研究会
- Place of Presentation
  横浜市
- Year and Date
  2013-10-02
- Data Source
  KAKENHI-PROJECT-23240129
[Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得2013
- Author(s)
  谷口博昭、山本博幸、越川直彦、清木元治、今井浩三
- Organizer
  第22回日本がん転移学会学術集会
- Place of Presentation
  松本市
- Data Source
  KAKENHI-PROJECT-24650632
[Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得とその臨床応用2013
- Author(s)
  谷口博昭、山本博幸、伊東文生、今井浩三
- Organizer
  第33回日本分子腫瘍マーカー研究会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2013-10-02
- Data Source
  KAKENHI-PROJECT-24650632
[Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得2012
- Author(s)
  谷口博昭,山本博幸,今井浩三
- Organizer
  72回日本癌学会学術総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23240129

1. IMAI Kohzoh (60117603)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
2. SUZUKI Hiromu (20381254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. Matsumura Yumiko (90594911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. NAKAMURA Takafumi (70432911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 長門石曉 (30550248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 山本浩文 (30322184)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 名取幸和 (40572912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 坂東聡史 (50990660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 赤井周司 (60192457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 横山雄起 (60615714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 森正樹 (70190999)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 江口英利 (90542118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 青木伊知男

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 西山伸宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 津本浩平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Taniguchi Hiroaki 谷口 博昭

TANIGUCHI Hiroaki 谷口 博昭

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多分子標的型核酸と高性能化DDSによって転移性癌をリセットするムーンショット計画

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Functional analysis and development for anti-tumor compounds targeted PRDM14 relating to cancer stemness based on protein-protein interactionPrincipal Investigator

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The development of gene therapy for breast cancer using targeted measles virus vectors

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Identification of specific cancer stem cell markers for diagnosis

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Development of novel gastrointestinal cancer diagnostic system based on large epige-nome analysis.

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Identification of regulatory system for cancer stemness and pplication to cancer therapeutics.Principal Investigator

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[Book] 固形がんの免疫・抗体療法-基礎研究の進歩と臨床応用-抗体療法の基礎(種類、特徴など)概論 日本臨床 70 巻 12 号2012

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[Book] 分子標 的薬-がんから他疾患までの治癒をめざ して-分子標的薬の作用機序・薬理作用- がん浸潤とその抑制日本臨床増刊号2012

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[Book] DDS を利用した抗 体医薬の展望 ドラッグデリバリーシステムの新展開 II - 核酸医薬・抗体医薬・ワクチ ン医療を支える DDS 技術-2012

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[Journal Article] PRDM14, a Zinc Finger Protein, Regulates Cancer Stemness2018

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[Journal Article] PRDM14 is overexpressed in chronic pancreatitis prior to pancreatic cancer.2018

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[Journal Article] PRDM14 directly interacts with heat shock proteins HSP90α and glucose-regulated protein 78.2018

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[Journal Article] Inhibition of PRDM14 expression in pancreatic cancer suppresses cancer stem-like properties and liver metastasis in mice2017

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[Journal Article] Silencing PRDM14 expression by an innovative RNAi therapy inhibits stemness, tumorigenicity, and metastasis of breast cancer2017

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[Journal Article] Cancer Stem Cells in Human Gastrointestinal Cancer.2016

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Taniguchi Hiroaki 谷口博昭

TANIGUCHI Hiroaki 谷口博昭

[Book] 固形がんの免疫・抗体療法-基礎研究の進歩と臨床応用-抗体療法の基礎(種類、特徴など)概論日本臨床 70 巻 12 号2012

[Book] 分子標的薬-がんから他疾患までの治癒をめざして-分子標的薬の作用機序・薬理作用- がん浸潤とその抑制日本臨床増刊号2012

[Book] DDS を利用した抗体医薬の展望ドラッグデリバリーシステムの新展開 II - 核酸医薬・抗体医薬・ワクチン医療を支える DDS 技術-2012