Katoh Takayuki 加藤敬行

… Alternative Names

TAKAYUKI Katoh 加藤敬行

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Researcher Number	90567760
Other IDs	https://orcid.org/0000-0001-6550-6203
Affiliation (Current)	2025: 東京大学, 大学院理学系研究科(理学部), 准教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 東京大学, 大学院理学系研究科(理学部), 准教授 2016 – 2017: 東京大学, 大学院理学系研究科(理学部), 助教 2013 – 2015: 東京大学, 理学(系)研究科(研究院), 助教 2010 – 2012: 東京大学, 大学院・理学系研究科, 助教
Review Section/Research Field	Principal Investigator Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Medium-sized Section 47:Pharmaceutical sciences and related fields / Basic Section 37010:Bio-related chemistry / Biomolecular chemistry / Chemical biology / Living organism molecular science
Keywords	Principal Investigator 翻訳 / ペプチド医薬 / tRNA / 特殊環状ペプチド / 遺伝暗号リプログラミング / ペプチド創薬 / 翻訳合成 / 非天然アミノ酸 / リボソーム / アゴニスト … More / 分子標的医薬 / 特殊ペプチド / マイクロRNA / 遺伝暗号 / フォルダマー / β-アミノ酸 / ペプチドミメティック / アミノキシ酸 / ヒドラジノ酸 / タンパク質間相互作用 / in vitroセレクション / 機能性RNA / 機能性ペプチド / GPCR / 医薬品探索 / RaPID display / 阻害剤 / RaPIDディスプレイ / 膜タンパク質 / FITシステム / mRNAディスプレイ / ケミカルバイオロジー Less

32種類のアミノ酸を利用可能な新型人工タンパク質翻訳系の開発Principal Investigator
- Principal Investigator
  
  加藤敬行
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokyo
環状β-アミノ酸含有フォルダマーペプチドライブラリの構築と新規ペプチド医薬の開発Principal Investigator
- Principal Investigator
  
  加藤敬行
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  The University of Tokyo
Ribosomal synthesis of peptidomimetics bearing non-amide backbonesPrincipal Investigator
- Principal Investigator
  
  Katoh Takayuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokyo
Depelopment of novel peptide drugs that regulate protein-protein interactionPrincipal Investigator
- Principal Investigator
  
  Katoh Takayuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  The University of Tokyo
Development of a ribosomal translation system that enables efficient incorporation of nonproteinogenic amino acidsPrincipal Investigator
- Principal Investigator
  
  Katoh Takayuki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  The University of Tokyo
In vitro selection of novel functional RNAs and peptides by means of natural RNA libraryPrincipal Investigator
- Principal Investigator
  
  Katoh Takayuki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomolecular chemistry
- Research Institution
  The University of Tokyo
Development of macrocylclic peptide drug that targets membrane proteins using cultivated human cell linesPrincipal Investigator
- Principal Investigator
  
  KATOH Takayuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Chemical biology
- Research Institution
  The University of Tokyo
In vitro selection of non-standard cyclic peptides that regulate maturation of miRNAsPrincipal Investigator
- Principal Investigator
  
  TAKAYUKI Katoh
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2014 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] 生命システム工学2012
- Author(s)
  加藤敬行、後藤佑樹、菅裕明, 他
- Total Pages
  213
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-24681047
[Book] 新しい薬学事典(ペプチド創薬の章)2011
- Author(s)
  加藤敬行、渡辺達哉、人見梓、青木由一郎、菅裕明
- Publisher
  朝倉書店(刊行確定)
- Data Source
  KAKENHI-PROJECT-22710210
[Journal Article] Cyclic β2,3-amino acids improve the serum stability of macrocyclic peptide inhibitors targeting the SARS-CoV-2 main protease2024
- Author(s)
  Miura Takashi、Malla Tika R、Brewitz Lennart、Tumber Anthony、Salah Eidarus、Lee Kang Ju、Terasaka Naohiro、Owen C David、Strain-Damerell Claire、Lukacik Petra、Walsh Martin A、Kawamura Akane、Schofield Christopher J、Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  Bulletin of the Chemical Society of Japan
  
  Volume: 未定 Issue: 5
- DOI
  10.1093/bulcsj/uoae018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18233, KAKENHI-PROJECT-22KJ0868, KAKENHI-PROJECT-22H00439
[Journal Article] Fine-tuning the tRNA anticodon arm for multiple/consecutive incorporations of β-amino acids and analogs2024
- Author(s)
  Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 未定 Issue: 11 Pages: 6586-6595
- DOI
  10.1093/nar/gkae219
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18233, KAKENHI-PROJECT-22H00439
[Journal Article] A comprehensive analysis of translational misdecoding pattern and its implication on genetic code evolution2023
- Author(s)
  Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 51 Issue: 19 Pages: 10642-10652
- DOI
  10.1093/nar/gkad707
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18233, KAKENHI-PROJECT-22H00439
[Journal Article] Ribosomal incorporation of negatively charged D-α- and N-methyl-L-α-amino acids enhanced by EF-Sep2023
- Author(s)
  Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  Philosophical Transactions of the Royal Society B: Biological Sciences
  
  Volume: 378 Issue: 1871 Pages: 20220038-20220038
- DOI
  10.1098/rstb.2022.0038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18233, KAKENHI-PROJECT-22H00439
[Journal Article] Translation initiation with exotic amino acids using EF-P-responsive artificial initiator tRNA2023
- Author(s)
  Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 51 Issue: 15 Pages: 8169-8180
- DOI
  10.1093/nar/gkad496
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18233, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-22H00439
[Journal Article] Drop-off-reinitiation at the amino termini of nascent peptides and its regulation by IF3, EF-G, and RRF2023
- Author(s)
  Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  RNA
  
  Volume: 29 Issue: 5 Pages: 663-674
- DOI
  10.1261/rna.079447.122
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18233, KAKENHI-PROJECT-22H00439
[Journal Article] In Vitro Selection of Macrocyclic α/β3-Peptides against Human EGFR2022
- Author(s)
  Wakabayashi Risa、Kawai Marina、Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 144 Issue: 40 Pages: 18504-18510
- DOI
  10.1021/jacs.2c07624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18233, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-22H00439, KAKENHI-PROJECT-21J11468
[Journal Article] Serum-Stable and Selective Backbone-N-Methylated Cyclic Peptides That Inhibit Prokaryotic Glycolytic Mutases2022
- Author(s)
  van Neer R.H.P.、Dranchak P. K.、Liu L.、Aitha M.、Queme B.、Kimura H.、Katoh T.、Battaile K. P.、Lovell S.、Inglese J.、Suga H.
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 17 Issue: 8 Pages: 2284-2295
- DOI
  10.1021/acschembio.2c00403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H00439
[Journal Article] Drop-off-reinitiation triggered by EF-G-driven mistranslocation and its alleviation by EF-P2022
- Author(s)
  Tajima Kenya、Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 50 Issue: 5 Pages: 2736-2753
- DOI
  10.1093/nar/gkac068
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02080, KAKENHI-PROJECT-20H05618
[Journal Article] In Vitro Genetic Code Reprogramming for the Expansion of Usable Noncanonical Amino Acids2022
- Author(s)
  Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  Annual Review of Biochemistry
  
  Volume: 91 Issue: 1 Pages: 221-243
- DOI
  10.1146/annurev-biochem-040320-103817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18233, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-22H00439
[Journal Article] In Vitro Selection of Foldamer-Like Macrocyclic Peptides Containing 2-Aminobenzoic Acid and 3-Aminothiophene-2-Carboxylic Acid2022
- Author(s)
  Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 144 Issue: 5 Pages: 2069-2072
- DOI
  10.1021/jacs.1c12133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-18H02080, KAKENHI-PROJECT-21K18233
[Journal Article] Uniform affinity-tuning of N-methyl-aminoacyl-tRNAs to EF-Tu enhances their multiple incorporation2021
- Author(s)
  Iwane Yoshihiko、Kimura Hiroyuki、Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 49 Issue: 19 Pages: 10807-10817
- DOI
  10.1093/nar/gkab288
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02080
[Journal Article] In Vitro Selection of Macrocyclic <scp>d</scp>/<scp>l</scp>-Hybrid Peptides against Human EGFR2021
- Author(s)
  Imanishi Sayaka、Katoh Takayuki、Yin Yizhen、Yamada Mituhiro、Kawai Marina、Suga Hiroaki
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 143 Issue: 15 Pages: 5680-5684
- DOI
  10.1021/jacs.1c02593
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-18H02080
[Journal Article] Consecutive Ribosomal Incorporation of α-Aminoxy/α-Hydrazino Acids with D/L-Configurations into Nascent Peptide Chains2021
- Author(s)
  Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 143 Issue: 45 Pages: 18844-18848
- DOI
  10.1021/jacs.1c09270
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02080, KAKENHI-PROJECT-21K18233
[Journal Article] In Vitro Selection of Thioether-Closed Macrocyclic Peptide by Means of the RaPID System2021
- Author(s)
  Katoh Takayuki、Goto Yuki、Suga Hiroaki
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2371 Pages: 247-259
- DOI
  10.1007/978-1-0716-1689-5_13
- ISBN
  9781071616888, 9781071616895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02080
[Journal Article] Ribosomal Elongation of Aminobenzoic Acid Derivatives2020
- Author(s)
  Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 142 Issue: 39 Pages: 16518-16522
- DOI
  10.1021/jacs.0c05765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-18H02080, KAKENHI-PLANNED-16H06444
[Journal Article] Ribosomal synthesis and de novo discovery of bioactive foldamer peptides containing cyclic β-amino acids2020
- Author(s)
  Katoh Takayuki、Sengoku Toru、Hirata Kunio、Ogata Kazuhiro、Suga Hiroaki
- Journal Title
  
  Nature Chemistry
  
  Volume: 12 Issue: 11 Pages: 1081-1088
- DOI
  10.1038/s41557-020-0525-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-18H02080, KAKENHI-PROJECT-18K19305, KAKENHI-PLANNED-16H06444
[Journal Article] Ribosomal Elongation of Cyclic γ-Amino Acids using a Reprogrammed Genetic Code2020
- Author(s)
  Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 142 Issue: 11 Pages: 4965-4969
- DOI
  10.1021/jacs.9b12280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02080, KAKENHI-PROJECT-20H05618
[Journal Article] Macrocyclic peptides exhibit antiviral effects against influenza virus HA and prevent pneumonia in animal models2020
- Author(s)
  Saito, M Itoh Y, Yasui F, Munakata T, Yamane D, Ozawa M, Ito R, Katoh T, Ishigaki H, Nakayama M, Shichinohe S, Yamaji K, Yamamoto N, Ikejiri A, Honda T, Sanada T, Sakoda Y, Kida H, Le TH, Kawaoka Y, Ogasawara Tsukiyama-Kohara T, Suga H, & Kohara M
- Journal Title
  
  Nature Comunications
  
  Volume: - Issue: 1 Pages: 2654-2654
- DOI
  10.1038/s41467-021-22964-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164, KAKENHI-PROJECT-18H02080, KAKENHI-PROJECT-23K21382
[Journal Article] Engineering Translation Components Improve Incorporation of Exotic Amino Acids2019
- Author(s)
  Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 3 Pages: 522-522
- DOI
  10.3390/ijms20030522
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02080
[Journal Article] Flexizyme-catalyzed synthesis of 3'-aminoacyl-NH-tRNAs.2019
- Author(s)
  Katoh T, Suga H.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: pii Issue: 9 Pages: e54-e54
- DOI
  10.1093/nar/gkz143
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204, KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-18H02080
[Journal Article] In vitro expression of genetically encoded non-standard peptides consisting of exotic amino acid building blocks.2018
- Author(s)
  Hirose H, Tsiamantas C, Katoh T, Suga H.
- Journal Title
  
  Curr Opin Biotechnol. 2018 Nov 16;58:
  
  Volume: 58 Pages: 28-36
- DOI
  10.1016/j.copbio.2018.10.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-18H02080, KAKENHI-PROJECT-18F18727
[Journal Article] Ribosomal Incorporation of Consecutive beta-Amino Acids.2018
- Author(s)
  Katoh T, Suga H.
- Journal Title
  
  J Am Chem Soc.
  
  Volume: 140 Issue: 38 Pages: 12159-12167
- DOI
  10.1021/jacs.8b07247
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-18H02080
[Journal Article] A human microRNA precursor binding to folic acid discovered by small RNA transcriptomic SELEX.2016
- Author(s)
  Naohiro Terasaka, Kazuki Futai, Takayuki Katoh, Hiroaki Suga.
- Journal Title
  
  RNA
  
  Volume: 22 Issue: 12 Pages: 1918-1928
- DOI
  10.1261/rna.057737.116
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26560429, KAKENHI-PROJECT-26220204
[Journal Article] tRid, an enabling method to isolate previously inaccessible small RNA fractions.2016
- Author(s)
  Kazuki Futai, Naohiro Terasaka, Takayuki Katoh, Hiroaki Suga.
- Journal Title
  
  Methods
  
  Volume: 106 Pages: 105-111
- DOI
  10.1016/j.ymeth.2016.04.033
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26560429, KAKENHI-PROJECT-26220204
[Journal Article] Selection-Based Discovery of Druglike Macrocyclic Peptides.2014
- Author(s)
  Passioura T, Katoh T, Goto Y, Suga H.
- Journal Title
  
  Annu. Rev. Biochem.
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24681047
[Journal Article] RNAワールドの実験的検証2013
- Author(s)
  岩根由彦、高辻諒、加藤敬行、菅裕明
- Journal Title
  
  進化分子工学
  
  Volume: なし Pages: 49-60
- Data Source
  KAKENHI-PROJECT-24681047
[Journal Article] A macrocyclic peptide that serves as a cocrystallization ligand and inhibits the function of a MATE family transporte2013
- Author(s)
  C・J・ Hipolito, Y・Tanaka, T・ Katoh, O・ Nureki, H・ Suga
- Journal Title
  
  Molecules
  
  Volume: 18 Issue: 9 Pages: 10514-30
- DOI
  10.3390/molecules180910514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01344, KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-24227004, KAKENHI-PROJECT-24681047
[Journal Article] Structural basis for the drug extrusion mechanism by a MATE multidrug transporter2013
- Author(s)
  Y・ Tanaka, C・J・ Hipolito, A・D・ Maturana, K・ Ito, T・ Kuroda, T・ Higuchi, T・ Katoh, H・E・ Kato, M・ Hattori, K・ Kumazaki, T・ Tsukazaki, R・ Ishitani, H・ Suga, O・ Nureki
- Journal Title
  
  Nature
  
  Volume: 496 Issue: 7444 Pages: 247-51
- DOI
  10.1038/nature12014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01344, KAKENHI-PROJECT-11J06643, KAKENHI-PROJECT-21000005, KAKENHI-PLANNED-22117007, KAKENHI-PUBLICLY-24121704, KAKENHI-PROJECT-24227004, KAKENHI-PROJECT-24570150, KAKENHI-PROJECT-24681047, KAKENHI-PROJECT-24687016, KAKENHI-PROJECT-25291011
[Journal Article] Selective thioether macrocyclization of peptides having the N-terminal 2-chloroacetyl group and competing two or three cysteine residues in translation2012
- Author(s)
  Iwasaki K, Goto Y, Katoh T, Suga H
- Journal Title
  
  Org Biomol Chem
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710210
[Journal Article] Selective thioether macrocyclization of peptides having the N-terminal 2-chloroacetyl group and competing two or three cysteine residues in translation2012
- Author(s)
  Kazuhiro Iwasaki, Yuki Goto, Takayuki Katoh, Hiroaki Suga
- Journal Title
  
  Org.Biomol.Chem.
  
  Volume: 10 Issue: 30 Pages: 5783-5786
- DOI
  10.1039/c2ob25306b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J09695, KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-22710210, KAKENHI-PROJECT-22750145, KAKENHI-PROJECT-24655146, KAKENHI-PROJECT-24681047
[Journal Article] Charging of tRNAs using ribozymes and selection of cyclic peptides containing thioethers2012
- Author(s)
  Reid PC, Goto Y, Katoh TSuga H
- Journal Title
  
  Methods Mol Biol
  
  Volume: 805 Pages: 335-348
- Data Source
  KAKENHI-PROJECT-22710210
[Journal Article] Natural product-like macrocyclic N-methyl-peptide inhibitors against a ubiquitin ligase uncovered from a ribosome-expressed de novo library2011
- Author(s)
  Y.Yamagishi, I.Shoji, S.Miyagawa, T.Kawakami, T.Katoh, Y.Goto, H.Suga*
- Journal Title
  
  Chemistry & Biology
  
  Volume: 18 Issue: 12 Pages: 1562-1570
- DOI
  10.1016/j.chembiol.2011.09.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-22710210, KAKENHI-PROJECT-22750145
[Journal Article] Charging of tRNAs using ribozymes and selection of cyclic peptides containing thioethers2011
- Author(s)
  Reid PC, Goto Y, Katoh T, Suga H
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 805 Pages: 335-348
- Data Source
  KAKENHI-PROJECT-22710210
[Journal Article] Natural product-like macro cyclic N-methyl-peptide inhibitors against ubiquitin ligase uncovered from ribosome-expressed de novo library2011
- Author(s)
  Yamagishi Y, ShoI, Miyagawa S, Kawakami T, Katoh T, Goto Y, Suga H
- Journal Title
  
  Chem Biol
  
  Volume: 18 Pages: 1562-1570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710210
[Journal Article] Flexizymes for genetic code reprogramming2011
- Author(s)
  Y.Goto, T.Katoh, H.Suga
- Journal Title
  
  Nature Protocols
  
  Volume: 6 Issue: 6 Pages: 779-790
- DOI
  10.1038/nprot.2011.331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-22710210, KAKENHI-PROJECT-22750145
[Journal Article] Ribosomal synthesis of backbone macro cyclic peptides2011
- Author(s)
  Katoh TGoto Y, Reza MS, Suga H
- Journal Title
  
  Chem Commun
  
  Volume: 47 Pages: 9946-9958
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710210
[Journal Article] Ribosomal synthesis of backbone macrocyclic peptides2011
- Author(s)
  T.Katoh, Y.Goto, S.Raza, H.Suga*
- Journal Title
  
  Chemical Communication
  
  Volume: 47 Issue: 36 Pages: 9946-9958
- DOI
  10.1039/c1cc12647d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-22710210, KAKENHI-PROJECT-22750145
[Journal Article] Flexizymes for genetic code reprogramming2011
- Author(s)
  Goto Y, Katoh T, Suga H
- Journal Title
  
  Nat Protoc
  
  Volume: 6 Pages: 779-790
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710210
[Journal Article] Drug discovery of non-standard peptide with genetic code reprogramming2011
- Author(s)
  山口淳, 加藤敬行, 菅裕明
- Journal Title
  
  Drug Delivery System
  
  Volume: 26 Issue: 6 Pages: 584-592
- DOI
  10.2745/dds.26.584
- NAID
  130002100330
- ISSN
  0913-5006, 1881-2732
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-22710210
[Journal Article] Flexizymes for genetic code reprogramming2011
- Author(s)
  Yuki Goto, Takayuki Katoh, Hiroaki Suga
- Journal Title
  
  Nature Protocols
  
  Volume: 6 Pages: 779-790
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710210
[Presentation] In Vitro Selection of Macrocyclic Peptides Containing α-Hydrazino Acid for Exploration of Drug Candidates2024
- Author(s)
  Satomi Matsumoto, Takayuki Katoh, Hiroaki Suga
- Organizer
  日本化学会年会
- Data Source
  KAKENHI-PROJECT-22H00439
[Presentation] RaPID 2.0: Going beyond the current accessible space of mRNA display2024
- Author(s)
  Alexis D. Richaud, Takayuki Katoh, Hiroaki Suga
- Organizer
  Gordon conference 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18233
[Presentation] In Vitro Selection of Macrocyclic Peptides Containing α-Hydrazino Acid for Exploration of Drug Candidates2024
- Author(s)
  Satomi Matsumoto, Takayuki Katoh, Hiroaki Suga
- Organizer
  日本化学会年会
- Data Source
  KAKENHI-PROJECT-21K18233
[Presentation] RaPID 2.0: Going beyond the current accessible space of mRNA display2024
- Author(s)
  Alexis D. Richaud, Takayuki Katoh, Hiroaki Suga
- Organizer
  Gordon conference 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00439
[Presentation] 非天然アミノ酸の効率的な翻訳導入に向けた tRNAのアンチコドンステムの最適化2023
- Author(s)
  平嶋瞭一, 加藤敬行, 菅裕明
- Organizer
  第55回若手ペプチド夏の勉強会
- Data Source
  KAKENHI-PROJECT-21K18233
[Presentation] Ribosomal synthesis of macrocyclic D/L-α/β/γ-hybrid peptide libraries for discovery of IFNGR1 inhibitors2023
- Author(s)
  Takashi Miura, Takayuki Katoh, Hiroaki Suga
- Organizer
  IPS2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18233
[Presentation] 非天然アミノ酸の効率的な翻訳導入に向けた tRNAのアンチコドンステムの最適化2023
- Author(s)
  平嶋瞭一, 加藤敬行, 菅裕明
- Organizer
  第55回若手ペプチド夏の勉強会
- Data Source
  KAKENHI-PROJECT-22H00439
[Presentation] Ribosomal synthesis of macrocyclic D/L-α/β/γ-hybrid peptide libraries for discovery of IFNGR1 inhibitors2023
- Author(s)
  Takashi Miura, Takayuki Katoh, Hiroaki Suga
- Organizer
  IPS2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00439
[Presentation] 剛直な開始基質を導入したダンベル型環状ペプチドライブラリの翻訳合成と薬剤候補探索の適用2023
- Author(s)
  會澤彩圭、R. H. P. van Neer、加藤敬行、菅裕明
- Organizer
  第55回若手ペプチド夏の勉強会
- Data Source
  KAKENHI-PROJECT-21K18233
[Presentation] 剛直な開始基質を導入したダンベル型環状ペプチドライブラリの翻訳合成と薬剤候補探索の適用2023
- Author(s)
  會澤彩圭、R. H. P. van Neer、加藤敬行、菅裕明
- Organizer
  第55回若手ペプチド夏の勉強会
- Data Source
  KAKENHI-PROJECT-22H00439
[Presentation] α-ヒドラジノ酸含有ペプチドライブラリの翻訳合成と薬剤候補探索への適用2022
- Author(s)
  松本聡美, 加藤敬行, 菅裕明
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-22H00439
[Presentation] α-ヒドラジノ酸含有ペプチドライブラリの翻訳合成と薬剤候補探索への適用2022
- Author(s)
  松本聡美, 加藤敬行, 菅裕明
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-21K18233
[Presentation] RIBOSOMAL SYNTHESIS OF A PEPTIDE LIBRARY CONTAINING CYCLIC γ-AMINO ACIDS FOR DISCOVERY OF SARS-CoV-2 MAIN PROTEASE INHIBITORS2022
- Author(s)
  Takashi Miura, Tika R. Malla, C. David Owen, Anthony Tumber, Lennart Brewitz, Michael A. McDonough, Eidarus Salah, Naohiro Terasaka, Takayuki Katoh, Petra Lukacik, Claire Strain-Damerell, Halina Mikolajek, Martin A. Walsh, Akane Kawamura, Christopher J. Schofield, and Hiroaki Suga
- Organizer
  第59回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-22H00439
[Presentation] In vitro selection of antibiotic peptides that inhibit the bacterial ribosome2022
- Author(s)
  Rei Takahashi, Takayuki Katoh, Axel Innis, Hiroaki Suga
- Organizer
  日本化学会
- Data Source
  KAKENHI-PROJECT-18H02080
[Presentation] 環状γ-アミノ酸含有ペプチドライブラリの構築および SARS-CoV-2 メインプロテアーゼ阻害剤のスクリーニング2022
- Author(s)
  三浦敬, Malla Tika, Owen David, Tumber Anthony, Brewitz Lennart, McDonough Michael, Salah Eidarus, 寺坂尚紘, 加藤敬行, Lukacik Petra, Strain-Damerell Claire, Mikolajek Halina, Walsh Martin, Kawamura Akane, Schofield Christopher, 菅裕明
- Organizer
  第21回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-22H00439
[Presentation] 環状γ-アミノ酸含有ペプチドを用いたSARS-CoV-2メインプロテアーゼ阻害剤のスクリーニング2022
- Author(s)
  三浦敬, Malla Tika, Owen David, Tumber Anthony, Brewitz Lennar, McDonough Michael, Salah Eidarus, 寺坂尚紘, 加藤敬行, Lukacik Petra, Strain-Damerell Claire, Mikolajek Halina, Walsh Martin, Kawamura Akane, Schofield Christopher, 菅裕明
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22H00439
[Presentation] 細胞膜透過型Helixペプチドライブラリーの構築とその薬剤候補探索への適用2022
- Author(s)
  大城裕亮・加藤敬行・菅裕明
- Organizer
  日本化学会
- Data Source
  KAKENHI-PROJECT-18H02080
[Presentation] 環状βアミノ酸を含む新規ヘリカルペプチド薬剤候補探索2022
- Author(s)
  川合茉利奈, 加藤敬行, Malla Tika, Tumber Anthony, Brewitz Lennar, McDonough Michael, Salah Eidraus, 寺坂尚紘, Kawamura Akane, Schofield Christopher, 菅裕明
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22H00439
[Presentation] 環状β-アミノ酸を含むヘリックスペプチドライブラリを用いた薬剤候補スクリーニング2020
- Author(s)
  川合茉利奈、加藤敬行、菅裕明
- Organizer
  日本化学会
- Data Source
  KAKENHI-PROJECT-18H02080
[Presentation] 環状γ-アミノ酸含有特殊ペプチドライブラリの構築と薬剤候補探索への適用2020
- Author(s)
  三浦敬、加藤敬行、菅裕明
- Organizer
  日本化学会
- Data Source
  KAKENHI-PROJECT-18H02080
[Presentation] Ribosomal synthesis and de novo discovery of bioactive foldamer peptides containing β- and D-amino acids2019
- Author(s)
  Takayuki Katoh
- Organizer
  12th International Symposium on Aminoacyl-tRNA Synthetases
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02080
[Presentation] Ribosomal incorporation of consecutive D- and β-amino acids2019
- Author(s)
  Katoh Takayuki、Suga Hiroaki
- Organizer
  RNA 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02080
[Presentation] Ribosomal incorporation of consecutive D- and β-amino acids2019
- Author(s)
  Takayuki Katoh, Hiroaki Suga
- Organizer
  Ribosome 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02080
[Presentation] Logical engineering of D-arm and T-stem of tRNA for incorporation of non-proteinogenic amino acids2018
- Author(s)
  Takayuki Katoh, Hiroaki Suga
- Organizer
  27th tRNA conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02080
[Presentation] Logical engineering of tRNA for incorporation of D- and β-amino acids into macrocyclic peptides2018
- Author(s)
  Takayuki Katoh
- Organizer
  4th International Conference on Circular Proteins and Peptides (ICCPP2018)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02080
[Presentation] 試験管内選択によるヒト内在性タンパク質間相互作用の網羅的探索法の開発2017
- Author(s)
  矢嶋亮・加藤敬行・菅裕明
- Organizer
  日本化学会
- Data Source
  KAKENHI-PROJECT-26560429
[Presentation] Exploration of human protein-protein or peptide-protein interactions by means of mRNA display.2017
- Author(s)
  Yajima, R., Hideshima, T., Katoh T., Suga H.
- Organizer
  日本化学会
- Data Source
  KAKENHI-PROJECT-26560429
[Presentation] 特殊環状ペプチド創薬2013
- Author(s)
  加藤敬行
- Organizer
  日本生化学会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Invited
- Data Source
  KAKENHI-PROJECT-24681047
[Presentation] ヒストンリシン脱メチル化酵素JMJD2Aに対する特殊環状ペプチド阻害剤のセレクション及び活性評価2012
- Author(s)
  小嶋達矢、加藤敬行、菅裕明
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶應義塾大学
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-22710210
[Presentation] 特殊環状ペプチドライブラリを用いた分子標的医薬の開発2011
- Author(s)
  加藤敬行
- Organizer
  第11回日本蛋白質科学会
- Place of Presentation
  大阪・ホテル阪急エキスポパーク(招待講演)
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PROJECT-22710210
[Presentation] 特殊環状ペプチドライブラリを用いた分子標的医薬の開発2011
- Author(s)
  加藤敬行
- Organizer
  第11回日本蛋白質科学会
- Place of Presentation
  大阪・ホテル阪急エキスポパーク
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PROJECT-22710210
[Presentation] In vitro selection of macrocyclic peptide inhibitors against various target proteins by means of ribosome-expressed peptide library2011
- Author(s)
  加藤敬行
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22710210
[Presentation] In vitro selection of macrocyclic peptide inhibitors against various target proteins by means of ribosome-expressed peptide library2011
- Author(s)
  加藤敬行
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  パシフィコ横浜(招待講演)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22710210
[Presentation] In vitroセレクションによる小分子結合性small non-coding RNAの探索2011
- Author(s)
  寺坂尚紘、加藤敬行、菅裕明
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22710210
[Presentation] 細胞を用いたRaPIDシステムによるIL28RA結合ペプチドの探索
- Author(s)
  石田啓、平田雄一、加藤敬行、小原道法、菅裕明
- Organizer
  第46回若手ペプチド夏の勉強会
- Place of Presentation
  京都府立青少年海洋センター（京都府宮津市）
- Year and Date
  2014-08-03 – 2014-08-05
- Data Source
  KAKENHI-PROJECT-24681047

1. SUGA Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results
2. Kato Bashiruddin, Nasir

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
3. 仙石徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. HIPOLITO CHRISTOPHER

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
5. 迫田義博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 小原恭子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Katoh Takayuki 加藤 敬行

TAKAYUKI Katoh 加藤 敬行

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32種類のアミノ酸を利用可能な新型人工タンパク質翻訳系の開発Principal Investigator

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環状β-アミノ酸含有フォルダマーペプチドライブラリの構築と新規ペプチド医薬の開発Principal Investigator

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Ribosomal synthesis of peptidomimetics bearing non-amide backbonesPrincipal Investigator

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Depelopment of novel peptide drugs that regulate protein-protein interactionPrincipal Investigator

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Development of a ribosomal translation system that enables efficient incorporation of nonproteinogenic amino acidsPrincipal Investigator

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In vitro selection of novel functional RNAs and peptides by means of natural RNA libraryPrincipal Investigator

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Development of macrocylclic peptide drug that targets membrane proteins using cultivated human cell linesPrincipal Investigator

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In vitro selection of non-standard cyclic peptides that regulate maturation of miRNAsPrincipal Investigator

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[Book] 生命システム工学2012

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[Book] 新しい薬学事典(ペプチド創薬の章)2011

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[Journal Article] Cyclic β2,3-amino acids improve the serum stability of macrocyclic peptide inhibitors targeting the SARS-CoV-2 main protease2024

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[Journal Article] Fine-tuning the tRNA anticodon arm for multiple/consecutive incorporations of β-amino acids and analogs2024

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[Journal Article] A comprehensive analysis of translational misdecoding pattern and its implication on genetic code evolution2023

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[Journal Article] Ribosomal incorporation of negatively charged D-α- and N-methyl-L-α-amino acids enhanced by EF-Sep2023

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Katoh Takayuki 加藤敬行

TAKAYUKI Katoh 加藤敬行