Mizohata Eiichi 溝端栄一

… Alternative Names

溝端栄一ミゾハタエイイチ

MIZOHATA Eiichi 溝端栄一

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Researcher Number	90571183
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院工学研究科, 講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 大阪大学, 大学院工学研究科, 講師 2019 – 2021: 大阪大学, 工学研究科, 講師 2016 – 2017: 大阪大学, 工学研究科, 講師 2014 – 2015: 大阪大学, 工学(系)研究科(研究院), 講師 2012 – 2014: 大阪大学, 工学(系)研究科(研究院), 助教 2012: 大阪大学, 大学院・工学研究科, 助教
Review Section/Research Field	Principal Investigator Structural biochemistry / Basic Section 43020:Structural biochemistry-related Except Principal Investigator Complex systems / Chemistry related to living body
Keywords	Principal Investigator 構造生物学 / X線結晶構造解析 / アニオンチャネル / 膜タンパク質 / X線自由電子レーザー / 構造生物化学 / SACLA / 生物無機化学 / 窒素代謝 / プロトン共役電子移動 … More / 常温無損傷構造 / 自由電子レーザー / 量子ビーム科学 / 国際情報交換 … More Except Principal Investigator 時分割X線結晶構造解析 / 微結晶 / XFEL / メカニズム / 酵素反応 / 結晶構造 / 反応メカニズム / 結晶構造解析 / 酵素 / 分子動画 / X線自由電子レーザー / 酵素反応メカニズム / RuBisCO / 2-オキソグルタル酸依存性ジオキシゲナーゼ / Rubisco / 発光タンパク質 / ディールスアルダー反応 / 高速分子動画 / 反応メカニズムの明 / プロスタグランジンD合成酵素 / 結晶の大型育成 / 反応メカニズムの解明 / プロスタグランジンＤ合成酵素 / 中性子線構造解析 / 酵素活性化機構 / 金属イオン / 中性子線解析 Less

XFEL異常散乱によるS型アニオンチャネルのイオン透過機構の可視化Principal Investigator
- Principal Investigator
  
  溝端栄一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Osaka University
Shooting Molecular Movies of Enzyme Reactions
- Principal Investigator
  
  Nagano Shingo
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tottori University
Serial femtosecond X-ray crystallography (SFX) of metalloproteins containing light-sensitive chemical structuresPrincipal Investigator
- Principal Investigator
  
  Mizohata Eiichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka University
X-ray crystallography of flavonoid metabolonPrincipal Investigator
- Principal Investigator
  
  MIZOHATA Eiichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka University
Neutron structure analysis of human PGD synthase for elucidation of the reaction mechanism activated by metal ions
- Principal Investigator
  
  INOUE Tsuyoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka University

[Book] 膜タンパク質工学ハンドブック『X線結晶解析による新規構造の解明』2020
- Author(s)
  山下恵太郎、溝端栄一
- Total Pages
  7
- Publisher
  (株)エヌ・ティー・エス
- ISBN
- Data Source
  KAKENHI-PLANNED-19H05780
[Book] 膜タンパク質工学ハンドブック『構造・解析―X線自由電子レーザーによる膜タンパク質の構造解析』2020
- Author(s)
  溝端栄一、久保稔
- Total Pages
  5
- Publisher
  (株)エヌ・ティー・エス
- ISBN
- Data Source
  KAKENHI-PLANNED-19H05780
[Journal Article] Rational design of an artificial ethylbenzene hydroxylase using a molecular dynamics simulation to enhance enantioselectivity2023
- Author(s)
  Oohora Koji、Kagawa Yoshiyuki、Nishiura Takako、Mizohata Eiichi、Schwaneberg Ulrich、Hayashi Takashi
- Journal Title
  
  Chemistry Letters
  
  Volume: 53 Issue: 2
- DOI
  10.1093/chemle/upad042
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17932, KAKENHI-PROJECT-22K21348, KAKENHI-PROJECT-20KK0315, KAKENHI-PROJECT-22K06103, KAKENHI-PROJECT-22KJ2064, KAKENHI-PROJECT-20H02755, KAKENHI-PLANNED-19H05780, KAKENHI-PUBLICLY-22H05364, KAKENHI-ORGANIZER-23H03830, KAKENHI-PLANNED-23H03832
[Journal Article] Functional diversity and plasticity in the sugar preferences of Saccharomyces MALT transporters in domesticated yeasts2022
- Author(s)
  Hatanaka Haruyo, Toyonaga Hiromi, Ishida Yukiko, Mizohata Eiichi, Ono Eiichiro
- Journal Title
  
  FEMS Yeast Research
  
  Volume: 22 Issue: 1
- DOI
  10.1093/femsyr/foac055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05780
[Journal Article] Substrate Specificity of an Aminopropyltransferase and the Biosynthesis Pathway of Polyamines in the Hyperthermophilic Crenarchaeon Pyrobaculum calidifontis2022
- Author(s)
  Fukuda Wakao、Osaki Mamoru、Yasuda Yusuke、Hidese Ryota、Higuchi Tsunehiko、Umezawa Naoki、Fujiwara Shinsuke、Mizohata Eiichi
- Journal Title
  
  Catalysts
  
  Volume: 12 Issue: 5 Pages: 567-567
- DOI
  10.3390/catal12050567
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06532, KAKENHI-PROJECT-21H02112, KAKENHI-PLANNED-19H05780
[Journal Article] Heavy Atom Detergent/Lipid Combined X-ray Crystallography for Elucidating the Structure-Function Relationships of Membrane Proteins2021
- Author(s)
  Shinya Hanashima, Takanori Nakane, Eiichi Mizohata*
- Journal Title
  
  Membranes (Basel)
  
  Volume: 11(11) Issue: 11 Pages: 823-823
- DOI
  10.3390/membranes11110823
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05780, KAKENHI-PROJECT-19K05713
[Journal Article] 連続フェムト秒解析で観る亜硝酸還元酵素の反応機構2017
- Author(s)
  溝端栄一
- Journal Title
  
  医学のあゆみ：生命現象を観る（医歯薬出版株式会社）
  
  Volume: 262 Pages: 407-412
- Data Source
  KAKENHI-PROJECT-15K18487
[Journal Article] Trends in Methods for Accelerating Structure Determination of Membrane Proteins2017
- Author(s)
  溝端栄一
- Journal Title
  
  Nihon Kessho Gakkaishi
  
  Volume: 59 Issue: 4 Pages: 147-148
- DOI
  10.5940/jcrsj.59.147
- NAID
  130006032054
- ISSN
  0369-4585, 1884-5576
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18487
[Journal Article] Redox-coupled proton transfer mechanism in nitrite reductase revealed by SPring-8 and SACLA2017
- Author(s)
  Eiichi Mizohata*, Yohta Fukuda, and Tsuyoshi Inoue
- Journal Title
  
  SPring-8/SACLA Research Frontiers 2016
  
  Volume: 2016 Pages: 26-27
- Data Source
  KAKENHI-PROJECT-15K18487
[Journal Article] Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate2017
- Author(s)
  Tosha Takehiko、Kubo Minoru, et. al
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 1-9
- DOI
  10.1038/s41467-017-01702-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05806, KAKENHI-PUBLICLY-17H05896, KAKENHI-PLANNED-26105012, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-15H03841, KAKENHI-PROJECT-17H03092, KAKENHI-PROJECT-15H05476, KAKENHI-PROJECT-15K18487
[Journal Article] Experimental phase determination with selenomethionine or mercury-derivatization in serial femtosecond crystallography.2017
- Author(s)
  Yamashita, K., et al.
- Journal Title
  
  IUCrJ
  
  Volume: 4 Issue: 5 Pages: 639-647
- DOI
  10.1107/s2052252517008557
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08262, KAKENHI-PROJECT-16H02282, KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-15K14468, KAKENHI-PROJECT-15K18487
[Journal Article] Damage-free protein structure determination by X-ray free electron laser2017
- Author(s)
  中根崇智, 岩田想, 溝端栄一
- Journal Title
  
  生化学
  
  Volume: 89 Issue: 4 Pages: 571-576
- DOI
  10.14952/SEIKAGAKU.2017.890571
- NAID
  40021312521
- ISSN
  0037-1017
- Year and Date
  2017-08-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18487
[Journal Article] A RuBisCO-mediated carbon metabolic pathway in methanogenic archaea2017
- Author(s)
  T. Kono, S. Mehrotra, C. Endo, N. Kizu, M. Matsuda, H. Kimura, E. Mizohata, T. Inoue, T. Hasunuma, A. Yokota, H. Matsumura, H. Ashida
- Journal Title
  
  Nature Commun.
  
  Volume: 8 Issue: 1 Pages: 14007-14007
- DOI
  10.1038/ncomms14007
- NAID
  120005947453
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H00783, KAKENHI-PLANNED-24109017, KAKENHI-PROJECT-16H02968, KAKENHI-PROJECT-25282230, KAKENHI-PROJECT-26292193, KAKENHI-PROJECT-15K18487
[Journal Article] Hydroxyethyl cellulose matrix applied to serial crystallography.2017
- Author(s)
  Michihiro Sugahara, Takanori Nakane, Tetsuya Masuda, Mamoru Suzuki, Shigeyuki Inoue, Changyong Song, Rie Tanaka, Toru Nakatsu, Eiichi Mizohata, Fumiaki Yumoto, Kensuke Tono, Yasumasa Joti, Takashi Kameshima, Takaki Hatsui, Makina Yabashi, Osamu Nureki, Keiji Numata, Eriko Nango, So Iwata
- Journal Title
  
  Scientific reports
  
  Volume: 7 Issue: 1 Pages: 703-703
- DOI
  10.1038/s41598-017-00761-0
- NAID
  120006223637
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440028, KAKENHI-PROJECT-15K18487
[Journal Article] X線自由電子レーザーによる膜タンパク質構造決定法2017
- Author(s)
  溝端栄一
- Journal Title
  
  バイオサイエンスとインダストリー
  
  Volume: 75 Pages: 415-417
- NAID
  40021341234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18487
[Journal Article] Serial femtosecond crystallography at the SACLA: breakthrough to dynamic structural biology2017
- Author(s)
  Mizohata Eiichi、Nakane Takanori、Fukuda Yohta、Nango Eriko、Iwata So
- Journal Title
  
  Biophysical Reviews
  
  Volume: 10 Issue: 2 Pages: 209-218
- DOI
  10.1007/s12551-017-0344-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17862, KAKENHI-PROJECT-15K18487
[Journal Article] Redox-coupled structural changes in nitrite reductase revealed by serial femtosecond and microfocus crystallography.2016
- Author(s)
  Fukuda Y, Tse KM, Suzuki M, Diederichs K, Hirata K, Nakane T, Sugahara M, Nango E, Tono K, Joti Y, Kameshima T, Song C, Hatsui T, Yabashi M, Nureki O, Matsumura H, Inoue T, Iwata S, Mizohata E.
- Journal Title
  
  J. Biochem
  
  Volume: 未定 Issue: 5 Pages: 527-538
- DOI
  10.1093/jb/mvv133
- NAID
  40020833586
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440028, KAKENHI-PROJECT-15K18487, KAKENHI-PLANNED-24109017, KAKENHI-PROJECT-25282230, KAKENHI-PROJECT-16H06294
[Journal Article] Redox-coupled proton transfer mechanism in nitrite reductase revealed by femtosecond crystallography.2016
- Author(s)
  Fukuda Y, Tse KM, Nakane T, Nakatsu T, Suzuki M, Sugahara M, Inoue S, Masuda T, Yumoto F, Matsugaki N, Nango E, Tono K, Joti Y, Kameshima T, Song C, Hatsui T, Yabashi M, Nureki O, Murphy ME, Inoue T, Iwata S, Mizohata E.
- Journal Title
  
  PNAS
  
  Volume: 113 Issue: 11 Pages: 2828-2933
- DOI
  10.1073/pnas.1517770113
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440028, KAKENHI-PROJECT-15K18487, KAKENHI-PLANNED-24109017, KAKENHI-PROJECT-25450167, KAKENHI-PROJECT-15K14941
[Journal Article] Membrane protein structure determination by SAD, SIR, or SIRAS phasing in serial femtosecond crystallography using an iododetergent2016
- Author(s)
  Takanori Nakane, Shinya Hanashima, Mamoru Suzuki, Haruka Saiki, Taichi Hayashi, Keisuke Kakinouchi, Shigeru Sugiyama, Satoshi Kawatake, Shigeru Matsuoka, Nobuaki Matsumori, et al
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 113 Issue: 46 Pages: 13039-13044
- DOI
  10.1073/pnas.1602531113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H00773, KAKENHI-PROJECT-15H03121, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-26440028, KAKENHI-PROJECT-26840021, KAKENHI-PROJECT-15K18487
[Journal Article] Crystal structure of streptavidin mutant with low immunogenicity.2015
- Author(s)
  Kawato T, Mizohata E, Meshizuka T, Doi H, Kawamura T, Matsumura H, Yumura K, Tsumoto K, Kodama T, Inoue T & Sugiyama A.
- Journal Title
  
  J Biosci Bioeng.
  
  Volume: 119(6) Issue: 6 Pages: 642-647
- DOI
  10.1016/j.jbiosc.2014.10.025
- NAID
  110009970751
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24109017, KAKENHI-PROJECT-24770096
[Journal Article] Structure-based design of a streptavidin mutant specific for an artificial biotin analogue2015
- Author(s)
  Kawato T, Mizohata E, Shimizu Y, Meshizuka T, Yamamoto T, Takasu N, Matsuoka M, Matsumura H, Kodama T, Kanai M, Doi H, Inoue T, Sugiyama A
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 157 Pages: 467-475
- NAID
  40020489250
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24770096
[Journal Article] Crystallization and preliminary X-ray crystallographic analysisof UDP-glucuronic acid :flavonol-3-O-glucuronosyltransferase2013
- Author(s)
  Mizohata, E., Okuda, T., Hatanaka, S., Nakayama, T., Horikawa, M., Nakayama, T., Ono, E., and Inoue, T.
- Journal Title
  
  (VvGT5) from the grapevine Vitis vinifera. Acta Cryst
  
  Volume: F69 Issue: 1 Pages: 65-68
- DOI
  10.1107/s1744309112045095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310135, KAKENHI-PROJECT-24770096
[Journal Article] The in silico screening and X-ray structure analysis of the inhibitor complex of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase2012
- Author(s)
  Y. Takashima, E. Mizohata, S. R. Krungkrai, Y. Fukunishi, T. Kinoshita, T. Sakata, H. Matsumura, J. Krungkrai, T. Horii & T. Inoue
- Journal Title
  
  J. Biochem.
  
  Volume: 152 Pages: 133-138
- NAID
  10031166122
- Data Source
  KAKENHI-PROJECT-22550152
[Journal Article] Crystal structure of rice Rubisco and implications for activation induced by positive effectors NADPH and 6-phosphogluconate2012
- Author(s)
  H. Matsumura, E. Mizohata, H. Ishida, A. Kogami, T. Ueno, A. Makino, T. Inoue, A. Yokota, T. Mae & Y. Kai*
- Journal Title
  
  J. Mol. Biol.
  
  Volume: 422 Pages: 75-86
- Data Source
  KAKENHI-PROJECT-22550152
[Journal Article] Structural insight into the stereoselective production of PGF_2αby Old Yellow Enzyme from Trypanosoma cruzi2011
- Author(s)
  N. Okamoto, K. Yamaguchi, E. Mizohata, K. Tokuoka, N. Uchiyama, S. Sugiyama, H. Matsumura, K. Inaka, Y. Urade, T. Inoue
- Journal Title
  
  J. of Biochemistry
  
  Volume: 150 Pages: 563-568
- Data Source
  KAKENHI-PROJECT-22550152
[Journal Article] Crystallization and preliminary X-ray diffraction analysis of mouse prostaglandin F_2αsynthase, AKR1B32011
- Author(s)
  Y. Takashima, S. Hatanaka, E. Mizohata, N. Nagata, Y. Fukunishi, H. Matsumura, Y. Urade, T. Inoue
- Journal Title
  
  Acta Cryst.
  
  Volume: F67 Pages: 1630-1632
- Data Source
  KAKENHI-PROJECT-22550152
[Journal Article] Structural insight into the stereoselective production of PGF2a by Old Yellow Enzyme from Trypanosoma cruzi2011
- Author(s)
  N.Okamoto, K.Yamaguchi, E.Mizohata, K.Tokuoka, N.Uchiyama, S.Sugiyama, H.Matsumura, K.Inaka, Y.Urade, T.Inoue
- Journal Title
  
  J.of Biochemistry
  
  Volume: 150(5) Issue: 5 Pages: 563-568
- DOI
  10.1093/jb/mvr096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22550152
[Journal Article] Crystallization and preliminary X-ray diffraction analysis of mouse prostaglandin F2a synthase, AKR1B32011
- Author(s)
  Y.Takashima, S.Hatanaka, E.Mizohata, N.Nagata, Y.Fukunishi, H.Matsumura, Y.Urade, T.Inoue
- Journal Title
  
  Acta Cryst
  
  Volume: F67 Issue: 12 Pages: 1630-1632
- DOI
  10.1107/s1744309111036165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22550152
[Patent] 膜タンパク質の安定化のための液体組成物および方法2023
- Inventor(s)
  藤田恭子, 溝端栄一, 古谷祐詞
- Industrial Property Rights Holder
  藤田恭子, 溝端栄一, 古谷祐詞
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-22K06103
[Patent] 重原子化化合物、膜タンパク質の結晶化を促進するための組成物、および該組成物を用いた膜タンパク質の構造解析方法2017
- Inventor(s)
  杉山, 花島, 溝端栄一, 村田, 井上, 斎木, 島田, 松森
- Industrial Property Rights Holder
  杉山, 花島, 溝端栄一, 村田, 井上, 斎木, 島田, 松森
- Industrial Property Rights Type
  特許
- Filing Date
  2017-02-27
- Overseas
- Data Source
  KAKENHI-PROJECT-15K18487
[Presentation] 次世代抗体医薬品開発へのアプローチ2024
- Author(s)
  ◯溝端栄一
- Organizer
  SAKIGAKEシンポジウム2024「量子生体科学のフロンティア：先駆的アプローチと未来の展望」
- Invited
- Data Source
  KAKENHI-PLANNED-19H05780
[Presentation] 次世代抗体医薬品開発へのアプローチ2024
- Author(s)
  溝端栄一
- Organizer
  SAKIGAKEシンポジウム2024「量子生体科学のフロンティア：先駆的アプローチと未来の展望」
- Invited
- Data Source
  KAKENHI-PROJECT-22K06103
[Presentation] 光スイッチング蛍光タンパク質rsGamillusの時分割構造解析2023
- Author(s)
  溝端栄一
- Organizer
  令和5年度新学術領域研究「高速分子動画」シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06103
[Presentation] X-ray crystallography of sesamin biosynthetic CYP81Q proteins2023
- Author(s)
  Eiichi Mizohata
- Organizer
  2023 ICCP450/JSSX
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06103
[Presentation] X-ray crystallography of sesamin biosynthetic CYP81Q proteins2023
- Author(s)
  ◯Eiichi Mizohata, Ryo Yonezawa, Kenshin Kondoh, Erisa Harada, Hiromi Toyonaga, Manabu Horikawa, Eiichiro Ono
- Organizer
  2023 International Joint Meeting of the 23rd International Conference on Cytochrome P450 and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05780
[Presentation] 水和イオン液体中における膜タンパク質の構造と熱安定性2023
- Author(s)
  石井佳穂、小林和音、市田公美、藤田恭子、溝端栄一、武部豊
- Organizer
  日本化学会第103春季年会(2023)
- Data Source
  KAKENHI-PROJECT-22K06103
[Presentation] 光スイッチング蛍光タンパク質rsGamillusの時分割構造解析2023
- Author(s)
  ◯溝端栄一
- Organizer
  令和5年度新学術領域研究「高速分子動画」シンポジウム
- Data Source
  KAKENHI-PLANNED-19H05780
[Presentation] Reaction mechanism of methylenedioxy bridge formation by a cytochrome P4502022
- Author(s)
  Kenshin Kondoh, Ryo Yonezawa, Eiichi Mizohata
- Organizer
  AsCA2022
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05780
[Presentation] CO2固定酵素 Rubiscoの動的構造解明への挑戦2022
- Author(s)
  溝端栄一
- Organizer
  第22回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05780
[Presentation] XFELを用いた光スイッチング蛍光タンパク質の時分割構造解析2022
- Author(s)
  溝端栄一
- Organizer
  テクノアリーナフォトニクス・センシング工学グループ第2回交流フォーラム
- Invited
- Data Source
  KAKENHI-PLANNED-19H05780
[Presentation] Damage-free protein observation and structure determination using X-ray free electron laser2021
- Author(s)
  ○Eiichi Mizohata
- Organizer
  Pacifichem 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05780
[Presentation] CO2固定酵素RuBisCOの分子動画撮影条件の検討2021
- Author(s)
  ◯清田雄大、熊野翔太、溝端栄一
- Organizer
  令和三年度新学術領域研究「高速分子動画」シンポジウム
- Data Source
  KAKENHI-PLANNED-19H05780
[Presentation] 銅含有亜硝酸還元酵素の動的結晶構造解析2020
- Author(s)
  ◯溝端栄一
- Organizer
  第93会日本生化学会大会, 「高速分子動画」共催シンポジウム, タンパク質の高速分子動画撮影の汎用化に向けて
- Data Source
  KAKENHI-PLANNED-19H05780
[Presentation] CO2固定酵素RuBisCOの分子動画撮影に向けた結晶調製2020
- Author(s)
  ◯清田雄大、熊野翔太、溝端栄一
- Organizer
  令和二年度新学術領域研究「高速分子動画」シンポジウム
- Data Source
  KAKENHI-PLANNED-19H05780
[Presentation] Rubiscoの分子動画撮影に向けた戦略2019
- Author(s)
  溝端栄一
- Organizer
  第１回高速分子動画のための光化学制御研究会
- Data Source
  KAKENHI-PLANNED-19H05780
[Presentation] X線自由電子レーザーを応用したタンパク質の動的結晶構造解析2019
- Author(s)
  溝端栄一
- Organizer
  日本プロテオーム学会2019年大会第70回日本電気泳動学会総会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05780
[Presentation] X線自由電子レーザーを利用したタンパク質の動的構造解析2019
- Author(s)
  溝端栄一
- Organizer
  文部科学省学術調査官特別会議
- Data Source
  KAKENHI-PLANNED-19H05780
[Presentation] CO2固定酵素Rubiscoの分子動画撮影に向けた研究2019
- Author(s)
  清田雄大、溝端栄一
- Organizer
  令和元年度新学術領域研究「高速分子動画」キックオフミーティング・膜タンパク質研究会
- Data Source
  KAKENHI-PLANNED-19H05780
[Presentation] 膜蛋白質の構造決定を加速化する技術の動向～XFELを用いた実験的位相決定法～2018
- Author(s)
  溝端栄一
- Organizer
  第31回日本放射光学会年会・放射光科学合同シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-15K18487
[Presentation] Damage-free protein structure determination using X-ray free electron laser at SACLA2017
- Author(s)
  Eiichi Mizohata
- Organizer
  Janelia Conference -Challenges in Structural Biology-
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18487
[Presentation] Redox-dependent structural change in nitrite reductase visualized by SPring-8 and SACLA2017
- Author(s)
  Eiichi Mizohata
- Organizer
  第55回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-15K18487
[Presentation] Proteins in Serial Femtosecond Crystallography2016
- Author(s)
  Eiichi Mizohata
- Organizer
  14th Conference of the Asian Crystallographic Association
- Place of Presentation
  ハノイ、ベトナム
- Year and Date
  2016-12-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18487
[Presentation] SACLAが拓く構造生物学の新時代2016
- Author(s)
  溝端栄一
- Organizer
  LSBM Symposium 2016, "超分子構造の計算科学"
- Place of Presentation
  東京大学先端科学技術研究センター（東京都・目黒区）
- Year and Date
  2016-05-12
- Invited
- Data Source
  KAKENHI-PROJECT-15K18487
[Presentation] SACLAが解明した銅含有亜硝酸還元酵素の常温無損傷構造2016
- Author(s)
  溝端栄一
- Organizer
  第１６回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場（福岡県・福岡市）
- Year and Date
  2016-06-07
- Invited
- Data Source
  KAKENHI-PROJECT-15K18487
[Presentation] Damage-free structure determination by SFX at SACLA2015
- Author(s)
  Mizohata E
- Organizer
  Workshop on serial femtosecond crystallography, SAXS, & Cryo-EM
- Place of Presentation
  Genentech Hall, UCSF, USA
- Year and Date
  2015-06-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18487
[Presentation] ブドウの有用二次代謝物を合成する糖転移酵素の構造解析2013
- Author(s)
  溝端栄一, 奥田卓馬, 畑中聖加, 中山泰亮, 松村浩由, 井上豪
- Organizer
  第2回JACI/GSCシンポジウム（第13回 GSCシンポジウム）
- Place of Presentation
  メルパルク大阪
- Data Source
  KAKENHI-PROJECT-24770096
[Presentation] Crystal structure of UDP-glucuronic acid:flavonol-3-Oglucuronosyltransferase from the grapevine Vitis vinifera2012
- Author(s)
  Eiichi Mizohata, Takuma Okuda, Seika Hatanaka, Taisuke Nakayama, Manabu Horikawa, Toru Nakayama, Eiichiro Ono, Tsuyoshi Inoue
- Organizer
  AsCA 12/CRYSTAL 28
- Place of Presentation
  Adelaide, Australia
- Data Source
  KAKENHI-PROJECT-24770096
[Presentation] Structural basis enzymes in the pyrimidine biosynthetic pathway of human malaria parasite Plasmodium falciparum for in silico drug design2011
- Author(s)
  Y.Takashima, E.Mizohata, K.Tokuoka, Y.Kusakari, T.Uchida, S.R.Krungkrai, H.Matsumura, J.Krungkrai, T.Horii, T.Inoue
- Organizer
  International Union of Crystallography
- Place of Presentation
  Madrid (Spain)
- Data Source
  KAKENHI-PROJECT-22550152
[Presentation] Structural basis enzymes in the pyrimidine biosynthetic pathway of human malaria parasite Plasmodium falciparumfor in silicodrug design2011
- Author(s)
  Y. Takashima, E. Mizohata, K. Tokuoka, Y. Kusakari, T. Uchida, S. R. Krungkrai, H. Matsumura, J. Krungkrai, T. Horii, T. Inoue
- Organizer
  International Union of Crystallography
- Place of Presentation
  Madrid(Spain)
- Data Source
  KAKENHI-PROJECT-22550152
[Presentation] Trypanosoma cruzi由来Old Yellow Enzymeの阻害剤複合体の結晶構造2010
- Author(s)
  山口桂史、岡本尚毅、徳岡啓司、杉山成、溝端栄一、松村浩由、伊中浩治、内山奈穂子、裏出良博
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  北海道・札幌市
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22550152

1. INOUE Tsuyoshi (20263204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
2. MATSUMURA Hiroyoshi (30324809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
3. Nagano Shingo (60286440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 中津亨 (50293949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 鈴木守

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. 中山亨

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 梅澤直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 松森信明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 林高史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 福田庸太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mizohata Eiichi 溝端 栄一

溝端 栄一 ミゾハタ エイイチ

MIZOHATA Eiichi 溝端 栄一

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XFEL異常散乱によるS型アニオンチャネルのイオン透過機構の可視化Principal Investigator

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Shooting Molecular Movies of Enzyme Reactions

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Serial femtosecond X-ray crystallography (SFX) of metalloproteins containing light-sensitive chemical structuresPrincipal Investigator

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X-ray crystallography of flavonoid metabolonPrincipal Investigator

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Neutron structure analysis of human PGD synthase for elucidation of the reaction mechanism activated by metal ions

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[Book] 膜タンパク質工学ハンドブック 『X線結晶解析による新規構造の解明』2020

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[Book] 膜タンパク質工学ハンドブック 『構造・解析―X線自由電子レーザーによる膜タンパク質の構造解析』2020

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[Journal Article] Rational design of an artificial ethylbenzene hydroxylase using a molecular dynamics simulation to enhance enantioselectivity2023

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[Journal Article] Functional diversity and plasticity in the sugar preferences of Saccharomyces MALT transporters in domesticated yeasts2022

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[Journal Article] Substrate Specificity of an Aminopropyltransferase and the Biosynthesis Pathway of Polyamines in the Hyperthermophilic Crenarchaeon Pyrobaculum calidifontis2022

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[Journal Article] Heavy Atom Detergent/Lipid Combined X-ray Crystallography for Elucidating the Structure-Function Relationships of Membrane Proteins2021

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[Journal Article] 連続フェムト秒解析で観る亜硝酸還元酵素の反応機構2017

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[Journal Article] Trends in Methods for Accelerating Structure Determination of Membrane Proteins2017

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Mizohata Eiichi 溝端栄一

溝端栄一ミゾハタエイイチ

MIZOHATA Eiichi 溝端栄一

[Book] 膜タンパク質工学ハンドブック『X線結晶解析による新規構造の解明』2020

[Book] 膜タンパク質工学ハンドブック『構造・解析―X線自由電子レーザーによる膜タンパク質の構造解析』2020