Kono Takeyuki 甲能武幸

Researcher Number	90573410
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 講師
Affiliation (based on the past Project Information) *help	2025: 慶應義塾大学, 医学部(信濃町), 講師 2022 – 2023: 慶應義塾大学, 医学部(信濃町), 講師 2021: 慶應義塾大学, 医学部(信濃町), 専任講師 2020: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 聴覚・平衡覚研究部, 研究員 2016 – 2017: 慶應義塾大学, 医学部(信濃町), 助教 2015: 慶應義塾大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology Except Principal Investigator Basic Section 56050:Otorhinolaryngology-related
Keywords	Principal Investigator HPV / 薬剤スクリーニング / 腫瘍増殖機構 / 3次元培養 / 再発性呼吸器乳頭腫 / shRNA / 予後予測因子 / 化学療法 / 中咽頭癌 / 阻害実験 … More / DNA損傷修復系 / 新規治療 / APOBEC / DNA損傷修復 / 頭頸部癌 / 声帯 / 霊長類 / MRI / 音響分析 / 萎縮 / コモンマーモセット / 粘膜固有層 / 声帯層構造 / 老人性喉頭 … More Except Principal Investigator 吃音症 / 早口言語症 / TMS / オルガノイド培養 / シングルセル解析 / ヒトパピローマウイルス / 喉頭乳頭腫 / 甲状腺オルガノイド / クラタリング / DTI / fMRI / 吃音 Less

甲状腺オルガノイドを用いた甲状腺機能低下症の病態解明と新規治療の開発
- Principal Investigator
  
  松居祐樹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Keio University
Elucidation of the Molecular and Cellular Pathogenesis of Recurrent Laryngeal Papillomatosis Based on Single-Cell Analysis and Exploration of Therapeutic Targets
- Principal Investigator
  
  上羽瑠美
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  The University of Tokyo
吃音症と早口言語症（クラタリング）の脳刺激研究による病態解明と治療法開発
- Principal Investigator
  
  富里周太
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Keio University
再発性呼吸器乳頭腫症の3次元培養細胞を用いた病態解明と新規治療薬の探索Principal Investigator
- Principal Investigator
  
  甲能武幸
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Keio University
吃音症と早口言語症（クラタリング）の鑑別診断の確立と脳画像解析による病態研究
- Principal Investigator
  
  富里周太
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Keio University
Expression of DNA damage repair factors and APOBEC3 in HPV-associated oropharyngeal carcinomaPrincipal Investigator
- Principal Investigator
  
  Kono Takeyuki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Keio University
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Investigation of clinical feature and treatment for presbylarynx in the most aged country, JapanPrincipal Investigator
- Principal Investigator
  
  Kono Takeyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Keio University

All 2024 2023 2022 2021 2020 2017 2016 2015

All Journal Article Presentation

[Journal Article] Low-Dose Cisplatin-Based Radiation Therapy for Refractory Recurrent Respiratory Papillomatosis2023
- Author(s)
  Takatsuki E, Kono T, Tomisato S, Ozawa H
- Journal Title
  
  Laryngoscope
  
  Volume: 134(5) Issue: 5 Pages: 2335-2337
- DOI
  10.1002/lary.31096
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08995
[Journal Article] Genomic Instability and DNA Damage Repair Pathways Induced by Humn Papillomaviruses.2021
- Author(s)
  Kono T, Laimins LA
- Journal Title
  
  Viruses
  
  Volume: 13 Issue: 9 Pages: 1821-1832
- DOI
  10.3390/v13091821
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18299
[Journal Article] Topoisomerase 2β induces DNA breaks to regulate human papillomavirus replication2021
- Author(s)
  Kaminski P, Hong S, Kono T, Hoover P, Laimins L
- Journal Title
  
  mbio
  
  Volume: 12 Issue: 1 Pages: 5-21
- DOI
  10.1128/mbio.00005-21
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18299
[Journal Article] Activation of DNA damage repair factors in HPV positive oropharyngeal cancers2020
- Author(s)
  Kono T, Hoover P, Poropatich K, Paunesku T, Mittal BB, Samant S, Laimins LA
- Journal Title
  
  Virology
  
  Volume: 547 Pages: 27-34
- DOI
  10.1016/j.virol.2020.05.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18299
[Journal Article] Pre-therapeutic nutritional assessment for predicting severe adverse events in patients with head and neck cancer treated by radiotherapy.2017
- Author(s)
  Kono T, Sakamoto K, Shinden S, Ogawa K.
- Journal Title
  
  Clinical　Nutrition
  
  Volume: 印刷中 Issue: 6 Pages: 1681-1685
- DOI
  10.1016/j.clnu.2016.10.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K20224
[Journal Article] Multidimensional vocal assessment after laser treatment for recurrent respiratory papillomatosis.2017
- Author(s)
  Kono T, Saito K, Yabe H, Uno K, Ogawa K.
- Journal Title
  
  Laryngoscope
  
  Volume: 127 Issue: 3 Pages: 679-684
- DOI
  10.1002/lary.26210
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20224, KAKENHI-PROJECT-17K11409
[Journal Article] Phonosurgical resection using submucosal infusion technique for precancerous laryngeal leukoplakia2016
- Author(s)
  Kono Takeyuki
- Journal Title
  
  Ｌａｒｙｎｇｏｓｃｏｐｅ
  
  Volume: 印刷中 Issue: 1 Pages: 153-158
- DOI
  10.1002/lary.26028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K20224
[Journal Article] Comparative multidimensional assessment of laryngeal function and quality of life after radiotherapy and laser surgery for early glottic cancer2016
- Author(s)
  Kono Takeyuki
- Journal Title
  
  Head Neck
  
  Volume: 印刷中 Issue: 7 Pages: 1085-1090
- DOI
  10.1002/hed.24412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K20224
[Presentation] Transoral Laser Microsurgery for Laryngopharyngeal Cancer2024
- Author(s)
  Takeyuki Kono
- Organizer
  19th Korea-Japan Joint Meeting of Otorhinolaryngology - Head and Neck Surgery
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08995
[Presentation] FANCD2 may serve as prognostic biomarker in HPV related oropharyngeal cancers2023
- Author(s)
  Takeyuki Kono, Hiroyuki Ozawa
- Organizer
  AHNS 11th International Conference on Head and Neck Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18299
[Presentation] 再発性呼吸器乳頭腫症3次元培養モデルの作成～HPVの生活環と腫瘍化メカニズムの解明を目指して～2023
- Author(s)
  甲能武幸
- Organizer
  日本気管食道科学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K08995
[Presentation] Establishment of 3D cell culture models for recurrent respiratory papillomatosis2023
- Author(s)
  Takeyuki Kono
- Organizer
  16th Taiwan-Japan Conference on Otorhinolaryngology - Head and Neck Surgery
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08995
[Presentation] FANCD2 may serve as prognostic biomarker in HPV related oropharyngeal cancers2022
- Author(s)
  甲能武幸、小沢宏之
- Organizer
  日本外科系連合
- Data Source
  KAKENHI-PROJECT-20K18299
[Presentation] HPV関連中咽頭癌におけるDNA損傷修復系因子の活性化と予後に関する検討2021
- Author(s)
  甲能武幸
- Organizer
  第31回日本頭頸部外科学会総会
- Data Source
  KAKENHI-PROJECT-20K18299
[Presentation] Vocal function after laser surgery for laryngeal papillomatosis2016
- Author(s)
  Takeyuki Kono
- Organizer
  American Academy of Otolaryngology Head and Neck Surgery Annual Meeting
- Place of Presentation
  サンディエゴ（アメリカ）
- Year and Date
  2016-09-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20224
[Presentation] コモンマーモセットの声帯における組織幹細胞の探索2016
- Author(s)
  Kono Ｔakeyuki
- Organizer
  コモンマーモセット研究会
- Place of Presentation
  慈恵医科大学校（東京都港区）
- Year and Date
  2016-01-27
- Data Source
  KAKENHI-PROJECT-15K20224
[Presentation] 老人性喉頭に対する声帯内コラーゲン注入術の治療成果2016
- Author(s)
  甲能　武幸
- Organizer
  第68回日本気管食道科学会総会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-15K20224
[Presentation] Clinical trends and vocal function of presbylarynx; Status of the most advanced aging country, Japan2016
- Author(s)
  Kono Takeyuki
- Organizer
  １６ｔｈ　Ｊａｐａｎ－Ｋｏｒｅａ　Ｊｏｉｎｔ　Ｍｅｅｔｉｎｇ　ｏｆ　Ｏｔｏｌａｒｙｎｇｏｌｏｇｙ　Ｈｅａｄ　ａｎｄ　Ｎｅｃｋ　Ｓｕｒｇｅｒｙ
- Place of Presentation
  ハイアットリージェンシー東京（東京都新宿区）
- Year and Date
  2016-03-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20224
[Presentation] Phonosurgical resection via the submucosal infusion;therapeutic method for laryngeal precancerosis2016
- Author(s)
  Takeyuki Kono
- Organizer
  19th WCBIP/WCBE World Congress
- Place of Presentation
  フィレンツェ（イタリア）
- Year and Date
  2016-05-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20224
[Presentation] Clinical trends and vocal function of presbylarynx; Status of the most advanced aging country, Japan2015
- Author(s)
  Kono Takeyuki
- Organizer
  Combined Otolaryngology Spring Meeting
- Place of Presentation
  ボストン（アメリカ）
- Year and Date
  2015-04-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20224

1. 富里周太 (00924987)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. 和佐野浩一郎 (40528866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 松居祐樹 (01010636)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 小澤宏之 (30327621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 御子柴卓弥 (50867017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 上羽瑠美 (10597131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 上羽悟史 (00447385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 齊藤祐毅 (40611009)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 矢田康人 (71011128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kono Takeyuki 甲能 武幸

Research Projects

Research Products

Co-Researchers

甲状腺オルガノイドを用いた甲状腺機能低下症の病態解明と新規治療の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the Molecular and Cellular Pathogenesis of Recurrent Laryngeal Papillomatosis Based on Single-Cell Analysis and Exploration of Therapeutic Targets

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

吃音症と早口言語症（クラタリング）の脳刺激研究による病態解明と治療法開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

再発性呼吸器乳頭腫症の3次元培養細胞を用いた病態解明と新規治療薬の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

吃音症と早口言語症（クラタリング）の鑑別診断の確立と脳画像解析による病態研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Expression of DNA damage repair factors and APOBEC3 in HPV-associated oropharyngeal carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of clinical feature and treatment for presbylarynx in the most aged country, JapanPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Low-Dose Cisplatin-Based Radiation Therapy for Refractory Recurrent Respiratory Papillomatosis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genomic Instability and DNA Damage Repair Pathways Induced by Humn Papillomaviruses.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Topoisomerase 2β induces DNA breaks to regulate human papillomavirus replication2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activation of DNA damage repair factors in HPV positive oropharyngeal cancers2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pre-therapeutic nutritional assessment for predicting severe adverse events in patients with head and neck cancer treated by radiotherapy.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multidimensional vocal assessment after laser treatment for recurrent respiratory papillomatosis.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phonosurgical resection using submucosal infusion technique for precancerous laryngeal leukoplakia2016

Author(s)

Journal Title

DOI

Kono Takeyuki 甲能武幸