SAITO AKIRA 齋藤朗

… Alternative Names

Saito Akira 齋藤朗

SAITO Akira 齋藤朗

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Researcher Number	90591412
Other IDs
Affiliation (Current)	2025: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 部長 2025: 東京大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2020 – 2025: 東京大学, 医学部附属病院, 講師 2020: 東京大学, 東京大学医学部附属病院, 講師 2018 – 2019: 東京大学, 保健・健康推進本部, 助教 2011 – 2016: 東京大学, 保健・健康推進本部, 助教 2012: 東京大学, 学内共同利用施設等, 助教
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Basic Section 49010:Pathological biochemistry-related / Respiratory organ internal medicine
Keywords	Principal Investigator トランスクリプトーム / 肺線維症 / RNAシーケンス / 線維芽細胞 / 肺胞上皮細胞 / 転写因子 / 肺線維芽細胞 / 遺伝子導入 / 初代培養 / 気管支上皮細胞 … More / マクロファージ / 呼吸器疾患 / 転写制御 / 遺伝子発現解析 / FOXL1 / TBX4 / スーパーエンハンサー / 肺癌 / 動物モデル / 三次元培養 / 転写ネットワーク / トランスクリプト―ム / 非小細胞肺癌 / 小細胞肺癌 / 肺上皮細胞 / リプログラミング / 遺伝子導入法 / 国際情報交換 / 分化誘導 … More Except Principal Investigator 病理解剖 / シングルセルRNAseq / microRNA / エピゲノム不均一性 / 肺癌 / CUT&Tag / ATAC-seq / 肥満喘息 / Visium / RAGE / S100A8 / 肥満喘息マウス / innate immunity / allergic inflammation / asthma / necroptosis / 急性呼吸窮迫症候群 / COVID-19 / 間質性肺炎 / 間質性肺疾患 / 肺気腫 / マクロファージ活性化症候群 / 炎症性サイトカイン / 歯周炎治療 / FLT-1 / カニクイザル / 3次元培養 / 歯周炎治療薬 / 三次元培養 / 初代培養 / 初代培養細胞 / VEGFR阻害剤 / コラーゲン分解 / シングルセルRNA-Seq / 歯周炎関連線維芽細胞 / 生体外歯周炎モデル / EGFR / ブレオマイシン / マウス / EGFRファミリー / プロテオグリカン / 肺線維症 Less

肺神経内分泌細胞の機能解析および呼吸器疾患病態における役割の解明Principal Investigator
- Principal Investigator
  
  齋藤朗
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
自然免疫系-ネクロトーシスのクロストークと気管支喘息病態の解明
- Principal Investigator
  
  石井崇史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
S100A8―RAGEシグナルに着目した肥満関連喘息の病態の解明
- Principal Investigator
  
  松崎博崇
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
剖検検体を活用した肺癌におけるエピゲノム不均一性の解明と新規治療法の探索
- Principal Investigator
  
  堀江真史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kanazawa University
線維芽細胞・マクロファージの相互作用に着目した肺線維化の病態解明Principal Investigator
- Principal Investigator
  
  齋藤朗
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
重症COVID-19合併ARDS・マクロファージ活性化症候群の新規治療戦略の確立
- Principal Investigator
  
  漆山博和
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
A novel trial for periodontitis treatment by administering anti-FLT1 antibody to the naturally-occurred periodontitis-affected cynomolgus monkey gingiva
- Principal Investigator
  
  山口洋子
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Nihon University
Organ-specificity of lung fibroblast and its relationship to lung diseasePrincipal Investigator
- Principal Investigator
  
  Saito Akira
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
Reprograming of lung epithelial cellsPrincipal Investigator
- Principal Investigator
  
  SAITO Akira
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
The role of proteoglycans in the modulation of EGFR family and it's ligand in lung fibrosis
- Principal Investigator
  
  JO Taisuke
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
Differentiation into airway epithelial cellsPrincipal Investigator
- Principal Investigator
  
  AKIRA Saito
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Endoscopic reflux esophagitis and decline in pulmonary function in nonsmokers: A retrospective cohort study2024
- Author(s)
  Enokido Takayoshi、Hiraishi Yoshihisa、Jo Taisuke、Urushiyama Hirokazu、Saito Akira、Noguchi Satoshi、Hosoki Keisuke、Ishii Takashi、Miyashita Naoya、Fukuda Kensuke、Matsuki Rei、Minatsuki Chihiro、Shimamoto Takeshi、Kage Hidenori、Yamamichi Nobutake、Matsuzaki Hirotaka
- Journal Title
  
  Respiratory Investigation
  
  Volume: 62 Issue: 4 Pages: 599-605
- DOI
  10.1016/j.resinv.2024.04.017
- Data Source
  KAKENHI-PROJECT-23K07648
[Journal Article] Anti-Inflammatory Effects of Japanese Herbal Medicine Hochuekkito in a Mouse Model of Acute Exacerbation of Chronic Obstructive Pulmonary Disease2024
- Author(s)
  Fukuda Kensuke、Matsuzaki Hirotaka、Hiraishi Yoshihisa、Miyashita Naoya、Ishii Takashi、Yuki Masaaki、Isago Hideaki、Tamiya Hiroyuki、Mitani Akihisa、Saito Akira、Jo Taisuke、Nagase Takahide
- Journal Title
  
  Pharmacology
  
  Volume: 109 Issue: 2 Pages: 121-126
- DOI
  10.1159/000536348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08277, KAKENHI-PROJECT-23K07648, KAKENHI-PROJECT-18K15946, KAKENHI-PROJECT-20K17176
[Journal Article] Quantitative evaluation model of variable diagnosis for chest X-ray images using deep learning2024
- Author(s)
  Nakagawa Shota、Ono Naoaki、Hakamata Yukichika、Ishii Takashi、Saito Akira、Yanagimoto Shintaro、Kanaya Shigehiko
- Journal Title
  
  PLOS Digital Health
  
  Volume: 3 Issue: 3 Pages: e0000460-e0000460
- DOI
  10.1371/journal.pdig.0000460
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0183, KAKENHI-PROJECT-22K08277, KAKENHI-PROJECT-21K12111
[Journal Article] An integrative epigenomic approach identifies ELF3 as an oncogenic regulator in ASCL1‐positive neuroendocrine carcinoma2023
- Author(s)
  Horie M, Tanaka H, Suzuki M, Sato Y, Takata S, Takai E, Miyashita N, Saito A, Nakatani Y, Yachida S
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 6 Pages: 2596-2608
- DOI
  10.1111/cas.15764
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06800, KAKENHI-PROJECT-22K08277, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-20K16440
[Journal Article] Distinct microRNA Signature and Suppression of ZFP36L1 Define ASCL1-Positive Lung Adenocarcinoma2023
- Author(s)
  Enokido Takayoshi、Horie Masafumi、Yoshino Seiko、Suzuki Hiroshi I.、Matsuki Rei、Brunnstrom Hans、Micke Patrick、Nagase Takahide、Saito Akira、Miyashita Naoya
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 22 Issue: 1 Pages: 29-40
- DOI
  10.1158/1541-7786.mcr-23-0229
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07210, KAKENHI-PROJECT-22K08277
[Journal Article] <scp>ASCL1</scp> regulates super‐enhancer‐associated <scp>miRNAs</scp> to define molecular subtypes of small cell lung cancer2022
- Author(s)
  Miyakawa Kazuko、Miyashita Naoya、Horie Masafumi、Terasaki Yasuhiro、Tanaka Hidenori、Urushiyama Hirokazu、Fukuda Kensuke、Okabe Yugo、Ishii Takashi、Kuwahara Naomi、Suzuki Hiroshi I.、Nagase Takahide、Saito Akira
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 11 Pages: 3932-3946
- DOI
  10.1111/cas.15481
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08553, KAKENHI-PROJECT-22K08277
[Journal Article] Targeting hepatocyte growth factor in epithelial-stromal interactions in an in vitro experimental model of human periodontitis.2021
- Author(s)
  Yamaguchi Y, Saito A, Horie M, Aoki A, Micke P, Ohshima M, Kappert K
- Journal Title
  
  Odontology
  
  Volume: 109 Issue: 4 Pages: 912-920
- DOI
  10.1007/s10266-021-00625-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07344, KAKENHI-PROJECT-20K09971
[Journal Article] A mouse model of asthma‐chronic obstructive pulmonary disease overlap induced by intratracheal papain2020
- Author(s)
  Fukuda Kensuke、Matsuzaki Hirotaka、Mikami Yu、Makita Kosuke、Miyakawa Kazuko、Miyashita Naoya、Hosoki Keisuke、Ishii Takashi、Noguchi Satoshi、Urushiyama Hirokazu、Horie Masafumi、Mitani Akihisa、Yamauchi Yasuhiro、Shimura Eri、Nakae Susumu、Saito Akira、Nagase Takahide、Hiraishi Yoshihisa
- Journal Title
  
  Allergy
  
  Volume: 76 Issue: 1 Pages: 390-394
- DOI
  10.1111/all.14528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15946, KAKENHI-PROJECT-20K17176, KAKENHI-PROJECT-18H02847, KAKENHI-PROJECT-18K08170
[Journal Article] Exophilin-5 regulates allergic airway inflammation by controlling IL-33-mediated Th2 responses2020
- Author(s)
  Katsuhide Okunishi, Hao Wang, Maho Suzukawa, Ray Ishizaki, Eri Kobayashi, Miho Kihara, Takaya Abe, Jun-ichi Miyazaki, Masafumi Horie, Akira Saito, Hirohisa Saito, Susumu Nakae, Tetsuro Izumi
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: - Issue: 7 Pages: 3919-3935
- DOI
  10.1172/jci127839
- NAID
  40022605127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09994, KAKENHI-PROJECT-20K08796, KAKENHI-PROJECT-18H02847, KAKENHI-PROJECT-19H03449, KAKENHI-PROJECT-18K08170, KAKENHI-PROJECT-20K15742
[Journal Article] FOXL1 Regulates Lung Fibroblast Function via Multiple Mechanisms2020
- Author(s)
  Miyashita Naoya、Horie Masafumi、Suzuki Hiroshi I.、Saito Minako、Mikami Yu、Okuda Kenichi、Boucher Richard C.、Suzukawa Maho、Hebisawa Akira、Saito Akira、Nagase Takahide
- Journal Title
  
  American Journal of Respiratory Cell and Molecular Biology
  
  Volume: 63 Issue: 6 Pages: 831-842
- DOI
  10.1165/rcmb.2019-0396oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-18K08170
[Journal Article] ASCL1 promotes tumor progression through cell-autonomous signaling and immune modulation in a subset of lung adenocarcinoma2020
- Author(s)
  Miyashita N, Horie M, Mikami Y, Urushiyama H, Fukuda K, Miyakawa K, Matsuzaki H, Makita K, Morishita Y, Harada H, Backman M, Lindskog C, Brunnstr;m H, Micke P, Nagase T, Saito A.
- Journal Title
  
  Cancer Lett
  
  Volume: 489 Pages: 121-132
- DOI
  10.1016/j.canlet.2020.06.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17176, KAKENHI-PROJECT-18K08170, KAKENHI-PROJECT-19K23981
[Journal Article] Pleural thickening on screening chest X-rays: a single institutional study.2019
- Author(s)
  Saito A, Hakamata Y, Yamada Y, Sunohara M, Tarui M, Murano Y, Mitani A, Tanaka K, Nagase T, Yanagimoto S.
- Journal Title
  
  Respir Res
  
  Volume: 20(1) Issue: 1 Pages: 138-138
- DOI
  10.1186/s12931-019-1116-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08170
[Journal Article] YAP/TAZ Signaling as a Molecular Link between Fibrosis and Cancer.2018
- Author(s)
  Noguchi S, Saito A, Nagase T.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 19(11) Issue: 11 Pages: 3674-3674
- DOI
  10.3390/ijms19113674
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08170
[Journal Article] Classification of lung adenocarcinoma transcriptome subtypes from pathological images using deep convolutional networks2018
- Author(s)
  3.Antonio, V. A. A., Ono, N., Saito, A., Sato, T., Altaf-Ul-Amin, M., & Kanaya, S.
- Journal Title
  
  International journal of computer assisted radiology and surgery
  
  Volume: 13(12) Issue: 12 Pages: 1905-1913
- DOI
  10.1007/s11548-018-1835-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K00406, KAKENHI-PROJECT-18K08170, KAKENHI-PUBLICLY-17H05297
[Journal Article] An Integrative Analysis of Transcriptome and Epigenome Features of ASCL1-Positive Lung Adenocarcinomas.2018
- Author(s)
  Miyashita N, Horie M, Suzuki HI, Yoshihara M, Djureinovic D, Persson J, Brunnstrom H, Lindskog C, Elfving H, Micke P, Saito A, Nagase T.
- Journal Title
  
  J Thorac Oncol
  
  Volume: 13(11) Issue: 11 Pages: 1676-1691
- DOI
  10.1016/j.jtho.2018.07.096
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08170, KAKENHI-PROJECT-16H02653
[Journal Article] The Role of TGF-β Signaling in Lung Cancer Associated with Idiopathic Pulmonary Fibrosis.2018
- Author(s)
  Saito A, Horie M, Micke P, Nagase T.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 19(11) Issue: 11 Pages: 3611-3611
- DOI
  10.3390/ijms19113611
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08170
[Journal Article] TGF-β Signaling in Lung Health and Disease.2018
- Author(s)
  Saito A, Horie M, Nagase T.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 19(8) Issue: 8 Pages: 2460-2460
- DOI
  10.3390/ijms19082460
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08170
[Journal Article] An integrative transcriptome analysis reveals a functional role for thyroid transcription factor-1 in small cell lung cancer.2018
- Author(s)
  Horie M, Miyashita N, Mattsson JSM, Mikami Y, Sandelin M, Brunnstrom H, Micke P, Nagase T, Saito A.
- Journal Title
  
  J Pathol
  
  Volume: 246(2) Issue: 2 Pages: 154-165
- DOI
  10.1002/path.5109
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08170, KAKENHI-PROJECT-16H02653
[Journal Article] Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling.2018
- Author(s)
  Suzuki HI, Horie M, Mihira H, Saito A.
- Journal Title
  
  J Vis Exp
  
  Volume: Aug 3 Issue: 138 Pages: 138-138
- DOI
  10.3791/57577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08170
[Journal Article] Regulation of TGF-β-mediated endothelial-mesenchymal transition by microRNA-272017
- Author(s)
  Suzuki HI, Katsura A, Mihira H, Horie M, Saito A, Miyazono K.
- Journal Title
  
  J Biochem.
  
  Volume: -- Issue: 5 Pages: 417-420
- DOI
  10.1093/jb/mvx017
- NAID
  40021219791
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-26461185
[Journal Article] TAZ contributes to pulmonary fibrosis by activating profibrotic functions of lung fibroblasts.2017
- Author(s)
  Noguchi S, Saito A, Mikami Y, Urushiyama H, Horie M, Matsuzaki H, Takeshima H, Makita K, Miyashita N, Mitani A, Jo T, Yamauchi Y, Terasaki Y, Nagase T.
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 42595-42595
- DOI
  10.1038/srep42595
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-26461185, KAKENHI-PROJECT-15K19172, KAKENHI-PROJECT-15K19414, KAKENHI-PROJECT-17K09630
[Journal Article] Profiling cancer testis antigens in non-small-cell lung cancer.2016
- Author(s)
  Djureinovic D, Hallstrom BM, Horie M, Mattsson JS, La Fleur L, Fagerberg L, Brunnstrom H, Lindskog C, Madjar K, Rahnenfuhrer J, Ekman S, Stahle E, Koyi H, Branden E, Edlund K, Hengstler JG, Lambe M, Saito A, Botling J, Ponten F, Uhlen M, Micke P
- Journal Title
  
  JCI Insight
  
  Volume: 1(10) Issue: 10
- DOI
  10.1172/jci.insight.86837
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461185
[Journal Article] Fibroblast VEGF-receptor 1 expression as molecular target in periodontitis2016
- Author(s)
  Ohshima M, Yamaguchi Y, Ambe K, Horie M, Saito A, Nagase T, Nakashima K, Ohki H, Kawai T, Abiko Y, Micke P, Kappert K
- Journal Title
  
  J Clin Periodontol
  
  Volume: 43(2) Issue: 2 Pages: 128-37
- DOI
  10.1111/jcpe.12495
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461185, KAKENHI-PROJECT-15K15768
[Journal Article] Integrated pathway-based transcription regulation network mining and visualization based on gene expression profiles.2016
- Author(s)
  Kibinge N, Ono N, Horie M, Sato T, Sugiura T, Altaf-Ul-Amin M, Saito A, Kanaya S
- Journal Title
  
  J Biomed Inform
  
  Volume: 61 Pages: 194-202
- DOI
  10.1016/j.jbi.2016.04.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461185
[Journal Article] YAP and TAZ modulate cell phenotype in a subset of small cell lung cancer.2016
- Author(s)
  Horie M, Saito A, Ohshima M, Suzuki HI, Nagase T.
- Journal Title
  
  Cancer Sci
  
  Volume: 107 Issue: 12 Pages: 1755-1766
- DOI
  10.1111/cas.13078
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-26461185, KAKENHI-PROJECT-16K18437
[Journal Article] Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis.2016
- Author(s)
  Horie M, Yamaguchi Y, Saito A, Nagase T, Lizio M, Itoh M, Kawaji H, Lassmann T, Carninci P, Forrest AR, Hayashizaki Y, Suzutani T, Kappert K, Micke P, Ohshima M.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1
- DOI
  10.1038/srep33666
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-26461185, KAKENHI-PROJECT-15K15768, KAKENHI-PROJECT-16K11843
[Journal Article] Hippo and TGF-β interplay in the lung field2015
- Author(s)
  Saito A, Nagase T
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol
  
  Volume: 309(8) Issue: 8 Pages: L756-L767
- DOI
  10.1152/ajplung.00238.2015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461185, KAKENHI-PROJECT-23249045
[Journal Article] Three-dimensional Co-culture Model for Tumor-stromal Interaction2015
- Author(s)
  Horie M, Saito A, Yamaguchi Y, Ohshima M, Nagase T
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 96 Issue: 96
- DOI
  10.3791/52469
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460137, KAKENHI-PROJECT-26461185
[Journal Article] Histamine induces human lung fibroblast-mediated collagen gel contraction via histamine H1 receptor2014
- Author(s)
  Horie M, Saito A, Yamauchi Y, Mikami Y, Sakamoto M, Jo T, Takizawa H, Nagase T, Kohyama T
- Journal Title
  
  Experimental Lung Research
  
  Volume: 未確定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591139
[Journal Article] Novel swine model of transfusion-related acute lung injury.2014
- Author(s)
  Okazaki H, Ishikawa O, Iijima T, Kohira T, Teranishi M, Kawasaki S, Saito A, Mikami Y, Sugiura A, Hashimoto S, Shimada E, Uchikawa M, Matsuhashi M, Tsuno NH, Tanaka M, Kiyokawa N, Fujimoto J, Nagase T, Tadokoro K, Takahashi K.
- Journal Title
  
  Transfusion.
  
  Volume: 54 Issue: 12 Pages: 3097-3107
- DOI
  10.1111/trf.12766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240066, KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-26461185
[Journal Article] Differential knockdown of TGF-β ligands in a three-dimensional co-culture tumor- stromal interaction model of lung cancer.2014
- Author(s)
  6.Horie M, Saito A, Noguchi S, Yamaguchi Y, Ohshima M, Morishita Y, Suzuki HI, Kohyama T, Nagase T.
- Journal Title
  
  BMC Cancer.
  
  Volume: 14 Issue: 1 Pages: 580-580
- DOI
  10.1186/1471-2407-14-580
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-25460137, KAKENHI-PROJECT-26461185
[Journal Article] Histamine induces human lung fibroblast-mediated collagen gel contraction via histamine H1 receptor.2014
- Author(s)
  5.Horie M, Saito A, Yamauchi Y, Mikami Y, Sakamoto M, Jo T, Nakajima J, Takizawa H, Nagase T, Kohyama T.
- Journal Title
  
  Exp Lung Res.
  
  Volume: 40 Issue: 5 Pages: 222-36
- DOI
  10.3109/01902148.2014.900155
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-23591139, KAKENHI-PROJECT-23790899, KAKENHI-PROJECT-24591154, KAKENHI-PROJECT-26461185
[Journal Article] An integrative analysis of the tumorigenic role of TAZ in human non-small cell lung cancer.2014
- Author(s)
  3.Noguchi S, Saito A, Horie M, Mikami Y, Suzuki HI, Morishita Y, Ohshima M, Abiko Y, Mattsson JS, König H, Lohr M, Edlund K, Botling J, Micke P, Nagase T
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 20 Issue: 17 Pages: 4660-72
- DOI
  10.1158/1078-0432.ccr-13-3328
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-26461185
[Journal Article] A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression2014
- Author(s)
  Isogaya K, Koinuma D, Tsutsumi S, Saito RA, Miyazawa K, Aburatani H, Miyazono K.
- Journal Title
  
  Cell Research
  
  Volume: 24 Issue: 8 Pages: 994-1008
- DOI
  10.1038/cr.2014.97
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22112001, KAKENHI-PROJECT-26461185, KAKENHI-PLANNED-22112002
[Journal Article] An integrated expression profiling reveals target genes of TGF-β and TNF-α possibly mediated by microRNAs in lung cancer cells2013
- Author(s)
  Akira Saito, Hiroshi I Iizuka, Masafumi Horie, Mitsuhiro Ohshima, Yasuyuki Morishita, Yoshimitsu Abiko, Takahide Nagase
- Journal Title
  
  PLoS ONE 8
  
  Volume: 8 Issue: 1 Pages: 158-163
- DOI
  10.1016/j.bbrc.2012.05.104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592637, KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-23790899
[Journal Article] An integrated expression profiling reveals target genes of TGF-βand TNF-αpossibly mediated by microRNAs in lung cancer cells2013
- Author(s)
  Saito A, Suzuki HI, Horie M, Ohshima M, Morishita Y, Abiko Y, Nagase T
- Journal Title
  
  PLoS One
  
  Volume: 8(2) Issue: 1
- DOI
  10.1371/annotation/874e0b87-0383-45ec-a250-3a4cd087dc86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790899
[Journal Article] EMT and EndMT: regulated in similar ways?2013
- Author(s)
  Akira Saito
- Journal Title
  
  Journal of Biochemistry
  
  Volume: 153(6) Issue: 6 Pages: 493-495
- DOI
  10.1093/jb/mvt032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790899
[Journal Article] CD99 is a novel prognostic stromal marker in non-small cell lung cancer2012
- Author(s)
  Edlund K, Lindskog C, Saito A, Berglund A, Pontén F, Göransson-Kultima H, Isaksson A, Jirström K, Planck M, Johansson L, Lambe M, Holmberg L, Nyberg F, Ekman S, Bergqvist M, Landelius P, Lamberg K, Botling J, Ostman A, Micke P
- Journal Title
  
  Int J Cancer
  
  Volume: 131(10) Issue: 10 Pages: 2264-73
- DOI
  10.1002/ijc.27518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790899
[Journal Article] Characterization of human lung cancer-associated fibroblasts in three dimensional in vitro co-culture model2012
- Author(s)
  Masafumi Horie, Akira Saito, Mitsuhiro Ohshima, Yasuyuki Morishita, Jun Nakajima, Tadashi Kohyama, Takahide Nagase
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 423 Issue: 2 Pages: 158-163
- DOI
  10.1371/journal.pone.0056587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592637, KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-23790899, KAKENHI-PROJECT-24689018, KAKENHI-PUBLICLY-23112702
[Presentation] ASCL1型肺小細胞癌におけるエピゲノムの全貌解明2023
- Author(s)
  堀江真史, 田中秀憲, 伊藤行信, 宮下直也, 齋藤朗, 前田大地
- Organizer
  日本病理学会総会
- Data Source
  KAKENHI-PROJECT-23K07649
[Presentation] ヒト歯周炎のin vitro実験モデルでの上皮-間葉相互作用における肝細胞増殖因子の役割2022
- Author(s)
  山口洋子，齋藤朗，堀江真史，青木章，Patrick Micke，Kai Kappert
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-20K07344
[Presentation] 肺小細胞癌のトランスクリプトーム解析2016
- Author(s)
  堀江真史、齋藤　朗、長瀬隆英
- Organizer
  日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26461185
[Presentation] 肺小細胞癌のトランスクリプトーム解析2016
- Author(s)
  堀江真史、齋藤　朗、長瀬隆英
- Organizer
  日本呼吸器学会
- Place of Presentation
  京都
- Year and Date
  2016-04-10
- Data Source
  KAKENHI-PROJECT-26461185
[Presentation] Hippo pathwayの構成因子であるTAZの肺線維症における役割2016
- Author(s)
  野口智史、齋藤　朗、三上　優、漆山博和、寺崎泰弘、堀江真史、松崎博崇、竹島英之、槇田広佑、三谷明久、山内康宏、長瀬隆英
- Organizer
  日本呼吸器学会
- Place of Presentation
  京都
- Year and Date
  2016-04-08
- Data Source
  KAKENHI-PROJECT-26461185
[Presentation] An integrated expression profiling reveals target genes of TGF-beta and TNF-alpha possibly mediated by microRNAs in lung cancer cells2013
- Author(s)
  Akira Saito
- Organizer
  American Thoracic Society
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2013-05-20
- Data Source
  KAKENHI-PROJECT-23790899
[Presentation] An integrated expression profiling reveals target genes of TGF-β and TNF-αpossibly mediated by microRNAs in lung cancer cells2012
- Author(s)
  齋藤朗
- Organizer
  2012 International Tumor Microenvironment Conference
- Place of Presentation
  Suzhou Dushu Lake Conference Center（中国・蘇州市）
- Data Source
  KAKENHI-PROJECT-23790899
[Presentation] An integrated expression profiling reveals target genes of TGF-beta and TNF-alpha possibly mediated by microRNAs in lung cancer cells2012
- Author(s)
  Akira Saito
- Organizer
  International Cancer Microenvironment Society
- Place of Presentation
  Suzhou, China
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-23790899
[Presentation] An Integrated Expression Profiling Reveals Target Genes Of TGF-β And TNF-α Possibly Mediated By microRNAs In Lung Cancer Cells
- Author(s)
  Akira Saito
- Organizer
  American Thoracic Society 2013
- Place of Presentation
  Pennsylvania Convention Center(アメリカ・フィラデルフィア)
- Data Source
  KAKENHI-PROJECT-23790899
[Presentation] エピソーマルベクターを用いた肺上皮細胞へのダイレクトリプログラミングの試み
- Author(s)
  堀江　真史，齋藤　　朗，野口　智史，長瀬　隆英
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  沖縄
- Year and Date
  2014-07-01 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-26461185

1. 堀江真史 (60732659)

# of Collaborated Projects: 5 results

# of Collaborated Products: 8 results
2. NAGASE Takaide (40208004)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
3. 山口洋子 (00239922)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 大島光宏 (30194145)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. 漆山博和 (20725303)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 石井崇史 (30803118)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. JO Taisuke (30376470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. YAMAUCHI Yasuhiro (00323585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. KOHYAMA Tadashi (00302703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 山海直 (80300937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 寺島裕也 (90538729)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 佐藤雅昭 (00623109)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 鹿毛秀宣 (80513390)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 鈴川真穂 (20453699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 松崎博崇 (00782187)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 福田健介 (50910759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 田中秀憲 (00804379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. SUZUKI Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. NOGUCHI Satoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. OKUNISHI Katsuhide

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. ONO Naoaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. MICKE Patrick

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
23. KACZKOWSKI Bogumil

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TERASAKI Mika

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 寺崎泰弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 宮園浩平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
27. 平石尚久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. AMIN MD.ALTAFUL

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 安孫子宜光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 油谷浩幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 鈴木雅美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 芳野聖子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAITO AKIRA 齋藤 朗

Saito Akira 齋藤 朗

SAITO Akira 齋藤 朗

Research Projects

Research Products

Co-Researchers

肺神経内分泌細胞の機能解析および呼吸器疾患病態における役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

自然免疫系-ネクロトーシスのクロストークと気管支喘息病態の解明

Principal Investigator

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Review Section

Research Institution

S100A8―RAGEシグナルに着目した肥満関連喘息の病態の解明

Principal Investigator

Project Period (FY)

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Research Institution

剖検検体を活用した肺癌におけるエピゲノム不均一性の解明と新規治療法の探索

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

線維芽細胞・マクロファージの相互作用に着目した肺線維化の病態解明Principal Investigator

Principal Investigator

Project Period (FY)

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重症COVID-19合併ARDS・マクロファージ活性化症候群の新規治療戦略の確立

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

A novel trial for periodontitis treatment by administering anti-FLT1 antibody to the naturally-occurred periodontitis-affected cynomolgus monkey gingiva

Principal Investigator

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Review Section

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Organ-specificity of lung fibroblast and its relationship to lung diseasePrincipal Investigator

Principal Investigator

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Reprograming of lung epithelial cellsPrincipal Investigator

Principal Investigator

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Research Institution

The role of proteoglycans in the modulation of EGFR family and it's ligand in lung fibrosis

Principal Investigator

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Research Institution

Differentiation into airway epithelial cellsPrincipal Investigator

Principal Investigator

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Research Institution

[Journal Article] Endoscopic reflux esophagitis and decline in pulmonary function in nonsmokers: A retrospective cohort study2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-Inflammatory Effects of Japanese Herbal Medicine Hochuekkito in a Mouse Model of Acute Exacerbation of Chronic Obstructive Pulmonary Disease2024

Author(s)

Journal Title

SAITO AKIRA 齋藤朗

Saito Akira 齋藤朗

SAITO Akira 齋藤朗