Kurashige Junji 藏重淳二

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KURASHIGE junji 藏重淳二

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Researcher Number	90594474
Other IDs
Affiliation (based on the past Project Information) *help	2021 – 2022: 熊本大学, 大学院生命科学研究部(医), 特定研究員 2020: 熊本大学, 病院, 非常勤診療医師 2017 – 2018: 熊本大学, 医学部附属病院, 非常勤診療医師 2016: 九州大学, 医学研究院, 助教 2015: 熊本大学, 医学部附属病院, 助教 … More 2014: 熊本大学, 医学部附属病院, 助手 2014: 熊本大学, 医学部附属病院, 特任助教 2013: 九州大学, 大学病院, その他 Less
Review Section/Research Field	Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related Except Principal Investigator Digestive surgery
Keywords	Principal Investigator 腹膜播種 / 胃癌 / エキソソーム / microRNA / 細胞外マトリックス / SERPINE2 / extracellular-matrix / PLOD2 / DDR2 / コラーゲン … More / c-Jun / c-Fos / activator protein-1 / gastric cancer / FOSB / c-FOS / AP-1 … More Except Principal Investigator C5aR / C5a / CAFs / 肝stellate cell / 大腸癌肝転移 / 肝星細胞 / C5a受容体 / 補体C5a Less

Investigation of the cause of gastric cancer peritoneal dissemination by exosome-encapsulated microRNA/gene regulationPrincipal Investigator
- Principal Investigator
  
  Kurashige Junji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
establishment of cancer treatment targeting C5a receptor and proteinase releaed by cancer cells
- Principal Investigator
  
  NITTA Hidetoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Identified genetic signature stimulated peritoneal dissemination in gastric cancerPrincipal Investigator
- Principal Investigator
  
  KURASHIGE Junji
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
  Kumamoto University
FOSB and c-Fos which constitute AP-1 expressed in the bone marrow at the advanced gastric cancer patientsPrincipal Investigator
- Principal Investigator
  
  KURASHIGE junji
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
  Kyushu University

All 2022 2021 2020 2016 2015 2014 2013 Other

All Journal Article Presentation Other

[Journal Article] Prophylactic laparoscopic total gastrectomy for gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS): the first report in Asia2022
- Author(s)
  Matsumoto Chihiro、Iwatsuki Masaaki、Iwagami Shiro、Morinaga Takeshi、Yamashita Kohei、Nakamura Kenichi、Eto Kojiro、Kurashige Junji、Baba Yoshifumi、Miyamoto Yuji、Yoshida Naoya、Komohara Yoshihiro、Baba Hideo
- Journal Title
  
  Gastric Cancer
  
  Volume: 25 Issue: 2 Pages: 473-478
- DOI
  10.1007/s10120-021-01253-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09107
[Journal Article] Dynamic Alteration in HLA-E Expression and Soluble HLA-E via Interaction with Natural Killer Cells in Gastric Cancer2022
- Author(s)
  Morinaga Takeshi、Iwatsuki Masaaki、Yamashita Kohei、Yasuda-Yoshihara Noriko、Yamane Taishi、Matsumoto Chihiro、Harada Kazuto、Eto Kojiro、Kurashige Junji、Ishimoto Takatsugu、Baba Yoshifumi、Miyamoto Yuji、Yoshida Naoya、Baba Hideo
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 30 Issue: 2 Pages: 1240-1252
- DOI
  10.1245/s10434-022-12505-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07594, KAKENHI-PROJECT-20K09107
[Journal Article] Evaluation of HLA-E Expression Combined with Natural Killer Cell Status as a Prognostic Factor for Advanced Gastric Cancer2022
- Author(s)
  Morinaga Takeshi、Iwatsuki Masaaki、Yamashita Kohei、Matsumoto Chihiro、Harada Kazuto、Kurashige Junji、Iwagami Shiro、Baba Yoshifumi、Yoshida Naoya、Komohara Yoshihiro、Baba Hideo
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: - Issue: 8 Pages: 4951-4960
- DOI
  10.1245/s10434-022-11665-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16308, KAKENHI-PROJECT-20K07594, KAKENHI-PROJECT-20K09107
[Journal Article] ASO Visual Abstract: Dynamic Alteration in HLA-E Expression and Soluble HLA-E via Interaction with Natural Killer Cells in Gastric Cancer2022
- Author(s)
  Morinaga Takeshi、Iwatsuki Masaaki、Yamashita Kohei、Yasuda-Yoshihara Noriko、Yamane Taishi、Matsumoto Chihiro、Harada Kazuto、Eto Kojiro、Kurashige Junji、Ishimoto Takatsugu、Baba Yoshifumi、Miyamoto Yuji、Yoshida Naoya、Baba Hideo
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 30 Issue: 2 Pages: 1253-1254
- DOI
  10.1245/s10434-022-12555-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09107
[Journal Article] Analysis of the survival and clinical characteristics of colorectal cancer patients with mental disorders2021
- Author(s)
  Kurashige Junji、Iwatsuki Masaaki、Mima Kosuke、Nomoto Daichi、Shigaki Hironobu、Yamashita Kohei、Morinaga Takeshi、Iwagami Shiro、Miyanari Nobutomo、Baba Hideo
- Journal Title
  
  Annals of Gastroenterological Surgery
  
  Volume: 5 Issue: 3 Pages: 314-320
- DOI
  10.1002/ags3.12421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09107
[Journal Article] Trastuzumab upregulates programmed death ligand-1 expression through interaction with NK cells in gastric cancer2020
- Author(s)
  Yamashita Kohei、Iwatsuki Masaaki、Yasuda-Yoshihara Noriko、Morinaga Takeshi、Nakao Yosuke、Harada Kazuto、Eto Kojiro、Kurashige Junji、Hiyoshi Yukiharu、Ishimoto Takatsugu、Nagai Yohei、Iwagami Shiro、Baba Yoshifumi、Miyamoto Yuji、Yoshida Naoya、Ajani Jaffer A.、Baba Hideo
- Journal Title
  
  British Journal of Cancer
  
  Volume: 124 Issue: 3 Pages: 595-603
- DOI
  10.1038/s41416-020-01138-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09107, KAKENHI-PROJECT-19K18095
[Journal Article] Oligometastatic recurrence as a prognostic factor after curative resection of esophageal squamous cell carcinoma2020
- Author(s)
  Morinaga Takeshi、Iwatsuki Masaaki、Yamashita Kohei、Harada Kazuto、Kurashige Junji、Nagai Yohei、Iwagami Shiro、Baba Yoshihumi、Yoshida Naoya、Baba Hideo
- Journal Title
  
  Surgery Today
  
  Volume: － Issue: 5 Pages: 798-806
- DOI
  10.1007/s00595-020-02173-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09107
[Journal Article] Two Asian families with gastric adenocarcinoma and proximal polyposis of the stomach successfully treated via laparoscopic total gastrectomy2020
- Author(s)
  Kanemitsu Kosuke、Iwatsuki Masaaki、Yamashita Kohei、Komohara Yoshihiro、Morinaga Takeshi、Iwagami Shiro、Eto Kojiro、Nagai Yohei、Kurashige Junji、Baba Yoshifumi、Yoshida Naoya、Baba Hideo
- Journal Title
  
  Clinical Journal of Gastroenterology
  
  Volume: 14 Issue: 1 Pages: 92-97
- DOI
  10.1007/s12328-020-01290-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09107
[Journal Article] Rapid diagnosis of lymph node metastasis in breast cancer using a new fluorescent method with γ-glutamyl hydroxymethyl rhodamine green.2016
- Author(s)
  Shinden Y, et al
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 27525-27525
- DOI
  10.1038/srep27525
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05951, KAKENHI-PROJECT-16H02606, KAKENHI-PROJECT-15H04921, KAKENHI-PROJECT-15K19899
[Journal Article] C5a receptor (CD88) promotes motility and invasiveness of gastric cancer by activating RhoA.2016
- Author(s)
  Kaida T, Nitta H, Kitano Y, Yamamura K, Arima K, Izumi D, Higashi T, Kurashige J, Imai K, Hayashi H, Iwatsuki M, Ishimoto T, Hashimoto D, Yamashita Y, Chikamoto A, Imanura T, Ishiko T, Beppu T, Baba H.
- Journal Title
  
  Oncotarget.
  
  Volume: 20(7) Issue: 51 Pages: 84798-84809
- DOI
  10.18632/oncotarget.12656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19900, KAKENHI-PROJECT-15K10171, KAKENHI-PROJECT-15K10191, KAKENHI-PROJECT-16K10503
[Journal Article] Triangulating Stapling Technique Covered with the Pedicled Omental Flap for Esophagogastric Anastomosis: A Safe Anastomosis with Fewer Complications2015
- Author(s)
  Yoshida N, Baba Y, Watanabe M, Hiyoshi Y, Ishimoto T, Iwagami S, Kurashige J, Sakamoto Y, Miyamoto Y, Baba H
- Journal Title
  
  J Am Coll Surg
  
  Volume: 220(2) Issue: 2 Pages: e13-e16
- DOI
  10.1016/j.jamcollsurg.2014.10.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462028, KAKENHI-PROJECT-25861200
[Journal Article] Epigenetic modulation and repression of miR-200b by cancer-associated fibroblasts contribute to cancer invasion and peritoneal dissemination in gastric cancer.2015
- Author(s)
  Kurashige J, Mima K, Sawada G, Takahashi Y, Eguchi H, Sugimachi K, Mori M, Yanagihara K, Yashiro M, Hirakawa K, Baba H, Mimori K.
- Journal Title
  
  Carcinogenesis.
  
  Volume: 36 Issue: 1 Pages: 133-41
- DOI
  10.1093/carcin/bgu232
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592005, KAKENHI-PROJECT-25861200, KAKENHI-PROJECT-26670608
[Journal Article] High expression of glucose transporter 1 on primary lesions of esophageal squamous cell carcinoma is associated with hematogenous recurrence2014
- Author(s)
  Sawayama H, Ishimoto T, Watanabe M, Yoshida N, Baba Y, Sugihara H, Izumi D, Kurashige J, Baba H
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 21(5) Issue: 5 Pages: 1756-62
- DOI
  10.1245/s10434-013-3371-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462028, KAKENHI-PROJECT-25861200, KAKENHI-PROJECT-26713042, KAKENHI-PROJECT-26893203
[Presentation] DDR2-collagen axis promote peritoneal dissemination in gastric cancer.2016
- Author(s)
  Junji Kurashige, Masaaki Iwatsuki, Daisuke Kuroda, Yuki Kiyozumi, Keisuke Kosumi, Daisuke Izumi, Kzsuto Harada, Ryuma Tokunaga, Hironobu Shigaki, Yoshio Sakamoto, Yuji Miyamoto, Yoshifumi Baba, Naoya Yoshida, Koshi Mimori, Hideo Baba
- Organizer
  10th AACR-JCA Joint Conference
- Place of Presentation
  Hyatt Regency Maui
- Year and Date
  2016-02-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19899
[Presentation] DDR2-collagen axis promote peritoneal dissemination in gastric cancer.2015
- Author(s)
  Junji Kurashige, Masaaki Iwatsuki, Daisuke Kuroda, Yuki Kiyozumi, Keisuke Kosumi, Daisuke Izumi, Kzsuto Harada, Ryuma Tokunaga, Hironobu Shigaki, Yoshio Sakamoto, Yuji Miyamoto, Yoshifumi Baba, Naoya Yoshida, Koshi Mimori, Hideo Baba
- Organizer
  3rd International Conference of Federation of Asian Clinical Oncology
- Place of Presentation
  国立京都国際会館（京都府）
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-15K19899
[Presentation] 胃癌骨髄中宿主細胞における転写因子AP-1（Fos/Jun）を標的とした新規治療法の確立2013
- Author(s)
  藏重　淳二
- Organizer
  第68回消化器外科学会
- Place of Presentation
  シーガイアコンベンションセンター
- Data Source
  KAKENHI-PROJECT-25861200
[Presentation] 癌腹膜播種モデルマウスを用いた腹膜播種規定因子の解明
- Author(s)
  藏重　淳二
- Organizer
  第46回胃病態機能研究会
- Place of Presentation
  横浜
- Year and Date
  2014-08-01 – 2014-08-02
- Data Source
  KAKENHI-PROJECT-25861200
[Presentation] 腹膜播種モデルマウスを用いた胃癌腹膜播種規定因子の解明
- Author(s)
  藏重　淳二
- Organizer
  第73回日本癌学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25861200
[]

1. NITTA Hidetoshi (90555749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 石本崇胤 (00594889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 岩槻政晃 (50452777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 小澄敬祐 (50594884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 江藤弘二郎 (40585717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. 原田和人 (70608869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 山下晃平 (00867202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. YOSHIDA Naoya

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
9. SUGIMACHI Keishi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 渡邊雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 馬場祥史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 澤山浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 江口英利

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 今井克憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kurashige Junji 藏重 淳二

KURASHIGE junji 藏重 淳二

Research Projects

Research Products

Co-Researchers

Investigation of the cause of gastric cancer peritoneal dissemination by exosome-encapsulated microRNA/gene regulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

establishment of cancer treatment targeting C5a receptor and proteinase releaed by cancer cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identified genetic signature stimulated peritoneal dissemination in gastric cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

FOSB and c-Fos which constitute AP-1 expressed in the bone marrow at the advanced gastric cancer patientsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Prophylactic laparoscopic total gastrectomy for gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS): the first report in Asia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dynamic Alteration in HLA-E Expression and Soluble HLA-E via Interaction with Natural Killer Cells in Gastric Cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of HLA-E Expression Combined with Natural Killer Cell Status as a Prognostic Factor for Advanced Gastric Cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ASO Visual Abstract: Dynamic Alteration in HLA-E Expression and Soluble HLA-E via Interaction with Natural Killer Cells in Gastric Cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of the survival and clinical characteristics of colorectal cancer patients with mental disorders2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Trastuzumab upregulates programmed death ligand-1 expression through interaction with NK cells in gastric cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oligometastatic recurrence as a prognostic factor after curative resection of esophageal squamous cell carcinoma2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Two Asian families with gastric adenocarcinoma and proximal polyposis of the stomach successfully treated via laparoscopic total gastrectomy2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rapid diagnosis of lymph node metastasis in breast cancer using a new fluorescent method with γ-glutamyl hydroxymethyl rhodamine green.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] C5a receptor (CD88) promotes motility and invasiveness of gastric cancer by activating RhoA.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Triangulating Stapling Technique Covered with the Pedicled Omental Flap for Esophagogastric Anastomosis: A Safe Anastomosis with Fewer Complications2015

Kurashige Junji 藏重淳二

KURASHIGE junji 藏重淳二