Onuma Kunishige 小沼邦重

… Alternative Names

Kunishige Onuma 小沼邦重

ONUMA Kunishige 小沼邦重

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Researcher Number	90597890
Other IDs	https://orcid.org/0000-0002-1034-5796
Affiliation (Current)	2025: 京都大学, 医学研究科, 特定助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 京都大学, 医学研究科, 特定助教 2019 – 2020: 京都大学, 医学研究科, 研究員 2012 – 2015: 鳥取大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Experimental pathology / Carcinogenesis Except Principal Investigator Basic Section 90120:Biomaterials-related / Basic Section 50010:Tumor biology-related / Medium-sized Section 50:Oncology and related fields
Keywords	Principal Investigator オルガノイド / 大腸がんオルガノイド / がん細胞集団の薬剤感受性 / micropapillary carcinoma / がん細胞集団の極性転換 / 腸管発癌 / 炎症 / がんの極性転換 / 癌細胞集団の転移能アッセイ / 細胞集団細胞極性 … More / 癌三次元培養法 / Micropapillary carcinoma / 極性転換と転移 / 薬剤感受性と極性転換 / 活性酸素 / 血管内皮との接着 / 大腸癌オルガノイド / がん細胞集団の転移 / 癌抑制遺伝子 / 癌遺伝子 / 発癌 … More Except Principal Investigator オルガノイド / ナノ粒子 / アップコンバージョン / 近赤外 / 光線力学療法 / 薬剤浸透評価 / ハイスループットスクリーニング / 薬剤探索研究 / ライブイメージング / スフェロイド / 細胞塊 / 治療戦略 / micropapillary / 極性 / 免疫回避 / 大腸癌 / 近赤外線 / 細胞深層部 / 光線力学 / 低酸素 / 一重項活性酸素 / 光増感剤 Less

Establishment of photodynamic therapy for deep cell tumors using the up-conversion method
- Principal Investigator
  
  粳間由幸
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Yonago National College of Technology
新しい細胞集塊薬剤浸透性評価モデルの開発
- Principal Investigator
  
  田中正太郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tokyo Women's Medical University
Micropapillary carcinomaの極性転換を標的とした治療戦略Principal Investigator
- Principal Investigator
  
  小沼邦重
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kyoto University
Mechanisms of the immune evasion through polarity switching of the colorectal cancer clusters
- Principal Investigator
  
  INOUE Masahiro
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Kyoto University
The mechanism of polarity switching in the cluster of human colorectal adenocarcinoma during the process of metastasisPrincipal Investigator
- Principal Investigator
  
  Kunishige Onuma
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kyoto University
Development of Deep Cellular Cancer Therapy Using Photosensitizer-Encapsulated Upconversion Particles
- Principal Investigator
  
  URUMA YOSHIYUKI
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Yonago National College of Technology
Studies on inflammation-induced intestinal bowel carcinogenesis by using organoidsPrincipal Investigator
- Principal Investigator
  
  onuma kunishige
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Tottori University
Mechanism of inflammation-accelerate colorectal carcinogenesis by reconstitutive modelPrincipal Investigator
- Principal Investigator
  
  ONUMA Kunishige
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Carcinogenesis
- Research Institution
  Tottori University

All 2024 2023 2022 2021 2020 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Clonal Origin and Lineage Ambiguity in Mixed Neuroendocrine Carcinoma of the Uterine Cervix2024
- Author(s)
  Masuda M、Iida K、Iwabuchi S、Tanaka M、Kubota S、Uematsu H、Onuma K、Kukita Y、Kato K、Kamiura S、Nakajima A、Coppo R、Kanda M、Yoshino K、Ueda Y、Morii E、Kimura T、Kondo J、Okada-Hatakeyama M、Hashimoto S、Inoue M
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 194 Issue: 3 Pages: 415-429
- DOI
  10.1016/j.ajpath.2023.11.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KF0212, KAKENHI-PROJECT-22K19456
[Journal Article] Oxygen metabolism analysis of a single organoid for non-invasive discrimination of cancer subpopulations with different growth capabilities2023
- Author(s)
  Nashimoto Yuji、Shishido Shotaro、Onuma Kunishige、Ino Kosuke、Inoue Masahiro、Shiku Hitoshi
- Journal Title
  
  Frontiers in Bioengineering and Biotechnology
  
  Volume: 11 Pages: 1184325-1184325
- DOI
  10.3389/fbioe.2023.1184325
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19456, KAKENHI-PROJECT-21H03803
[Journal Article] Inhibition of the bone morphogenetic protein pathway suppresses tumor growth through downregulation of epidermal growth factor receptor in <scp>MEK</scp>/<scp>ERK</scp>‐dependent colorectal cancer2023
- Author(s)
  Shimizu Shota、Kondo Jumpei、Onuma Kunishige、Coppo Roberto、Ota Kasumi、Kamada Mayumi、Harada Yohei、Tanaka Yoshihisa、Nakazawa Mai Adachi、Tamada Yoshinori、Okuno Yasushi、Kawada Kenji、Obama Kazutaka、Coffey Robert J.、Fujiwara Yoshiyuki、Inoue Masahiro
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 9 Pages: 3636-3648
- DOI
  10.1111/cas.15882
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KF0212, KAKENHI-PROJECT-21K07942, KAKENHI-PROJECT-22K19456, KAKENHI-PROJECT-21H03537
[Journal Article] Electrochemical sensing of oxygen metabolism for a three-dimensional cultured model with biomimetic vascular flow2023
- Author(s)
  Nashimoto Yuji、Mukomoto Rei、Imaizumi Takuto、Terai Takato、Shishido Shotaro、Ino Kosuke、Yokokawa Ryuji、Miura Takashi、Onuma Kunishige、Inoue Masahiro、Shiku Hitoshi
- Journal Title
  
  Biosensors and Bioelectronics
  
  Volume: 219 Pages: 114808-114808
- DOI
  10.1016/j.bios.2022.114808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19456, KAKENHI-PROJECT-21H02714, KAKENHI-PROJECT-21H03803, KAKENHI-PROJECT-21H01957
[Journal Article] Tracking the growth fate of single cells and isolating slow-growing cells in human colorectal cancer organoids2023
- Author(s)
  Coppo Roberto、Kondo Jumpei、Onuma Kunishige、Inoue Masahiro
- Journal Title
  
  STAR Protocols
  
  Volume: 4 Issue: 3 Pages: 102395-102395
- DOI
  10.1016/j.xpro.2023.102395
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KF0212, KAKENHI-PROJECT-22K19456, KAKENHI-PROJECT-21H02714
[Journal Article] Distinct but interchangeable subpopulations of colorectal cancer cells with different growth fates and drug sensitivity2023
- Author(s)
  Coppo Roberto、Kondo Jumpei、Iida Keita、Okada Mariko、Onuma Kunishige、Tanaka Yoshihisa、Kamada Mayumi、Ohue Masayuki、Kawada Kenji、Obama Kazutaka、Inoue Masahiro
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 2 Pages: 105962-105962
- DOI
  10.1016/j.isci.2023.105962
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07942, KAKENHI-PROJECT-22K19456, KAKENHI-PROJECT-21H02714, KAKENHI-PROJECT-22KF0212, KAKENHI-PROJECT-21H03537
[Journal Article] De-differentiation in cultures of organoids from luminal-type breast cancer is restored by inhibition of NOTCH signaling2023
- Author(s)
  Uematsu Hiroyuki、Saito Chieko、Kondo Jumpei、Onuma Kunishige、Coppo Roberto、Mori Yukiko、Muto Manabu、Kikawa Yuichiro、Tada Manami、Sugie Tomoharu、Inoue Masahiro
- Journal Title
  
  Human Cell
  
  Volume: 36 Issue: 6 Pages: 2099-2112
- DOI
  10.1007/s13577-023-00975-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KF0212, KAKENHI-PROJECT-22K19456
[Journal Article] Abnormality of apico?basal polarity in adenocarcinoma2022
- Author(s)
  Onuma Kunishige、Inoue Masahiro
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 11 Pages: 3657-3663
- DOI
  10.1111/cas.15549
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19456, KAKENHI-PROJECT-21H02714, KAKENHI-PROJECT-20K08286
[Journal Article] Polarity switching of ovarian cancer cell clusters via <scp>SRC</scp> family kinase is involved in the peritoneal dissemination2022
- Author(s)
  Kawata Mayuko、Kondo Jumpei、Onuma Kunishige、Ito Yu、Yokoi Takeshi、Hamanishi Junzo、Mandai Masaki、Kimura Tadashi、Inoue Masahiro
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 10 Pages: 3437-3448
- DOI
  10.1111/cas.15493
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07942, KAKENHI-PROJECT-21K09541, KAKENHI-PROJECT-22K19456, KAKENHI-PROJECT-21H02714, KAKENHI-PROJECT-23K21473
[Journal Article] Ex vivo chemosensitivity assay using primary ovarian cancer organoids for predicting clinical response and screening effective drugs2022
- Author(s)
  Ito Yu、Kondo Jumpei、Masuda Masamune、Matsuzaki Shinya、Onuma Kunishige、Kanda Mizuki、Watanabe Yuko、Sakaguchi Hitomi、Yoshino Kiyoshi、Ueda Yutaka、Kamiura Shoji、Kimura Tadashi、Inoue Masahiro
- Journal Title
  
  Human Cell
  
  Volume: 36 Issue: 2 Pages: 752-761
- DOI
  10.1007/s13577-022-00827-w
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09657, KAKENHI-PROJECT-22K19456, KAKENHI-PROJECT-21H02714
[Journal Article] Fermented brown rice and rice bran with Aspergillus oryzae (FBRA) prevents inflammation-related carcinogenesis in mice, by inhibiting infiltration of inflammatory cells2015
- Author(s)
  Onuma K, Kanda Y, Suzuki Ikeda S, Sakaki R, Nonomura T, Kobayashi M, Osaki M, Shikanai M, Kobayashi H and Okada F.
- Journal Title
  
  Nutrients
  
  Volume: 7 Issue: 12 Pages: 10237-10250
- DOI
  10.3390/nu7125531
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460472, KAKENHI-PROJECT-15J07285, KAKENHI-PROJECT-26860264
[Journal Article] Fascin regulates chronic inflammation-related human colon carcinogenesis by inhibiting cell anoikis2014
- Author(s)
  Kanda Y, Kawaguchi T, Kuramitsu Y, Kitagawa T, Kobayashi T, Takahashi N, Tazawa H, Habelhah H, Hamada J-I, Kobayashi M, Hirahata M, Onuma K, Osaki M, Nakamura K, Kitagawa T, Hosokawa M and Okada F.
- Journal Title
  
  Proteomics
  
  Volume: 14 Issue: 9 Pages: 1031-1041
- DOI
  10.1002/pmic.201300414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590461, KAKENHI-PROJECT-24501352, KAKENHI-PROJECT-24700959, KAKENHI-PROJECT-26460472, KAKENHI-PROJECT-26860264
[Journal Article] Fascin regulates chronic inflammation-related human colon carcinogenesis by inhibiting cell anoikis2014
- Author(s)
  Kanda Y, Kawaguchi T, Kuramitsu Y, Kitagawa T, Kobayashi T, Takahashi N, Tazawa H, Habelhah H, Hamada J-I, Kobayashi M, Hirahata M, Onuma K, Osaki M, Nakamura K, Kitagawa T, Hosokawa M and Okada F
- Journal Title
  
  Proteomics
  
  Volume: 14(9) Pages: 1031-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700959
[Journal Article] Genetic reconstitution of tumorigenesis in primary intestinal cells2013
- Author(s)
  Onuma K, Ochiai M, Orihashi K, Takahashi M, Imai T, Nakagama H, Hippo Y
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 110 Pages: 11127-11132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700959
[Presentation] Micropapillary carcinoma病態における極性転換とその分子機構2023
- Author(s)
  小沼邦重
- Organizer
  第47回日本リンパ学会総会
- Data Source
  KAKENHI-PROJECT-23K07395
[Presentation] Micropapillary carcinomaの薬剤感受性における極性転換の役割2023
- Author(s)
  小沼邦重、井上正宏
- Organizer
  日本がん転移学会
- Data Source
  KAKENHI-PROJECT-20K08286
[Presentation] Role of polarity switching in micropapillarycarcinoma in drug sensitivity2023
- Author(s)
  小沼邦重
- Organizer
  第32回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-23K07395
[Presentation] Micropapillary carcinomaの極性転換不全を標的とした治療戦略2023
- Author(s)
  小沼邦重、井上正宏
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08286
[Presentation] 大腸癌de novo　クラスターが示す細胞運命のNotchシグナルによる制御2023
- Author(s)
  小沼邦重, 井上正宏
- Organizer
  第9回細胞凝集研究会
- Data Source
  KAKENHI-PROJECT-22K19456
[Presentation] Micropapillary carcinomaの薬剤感受性における極性転換の役割.2023
- Author(s)
  小沼邦重, 井上正宏
- Organizer
  第32回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-22K19456
[Presentation] Micropapillary carcinoma の極性転換不全を標的とした治療戦略2023
- Author(s)
  小沼邦重, 井上正宏
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19456
[Presentation] オルガノイド内でがん細胞が構成する社会の多様性と可塑性2023
- Author(s)
  小沼邦重, 井上正宏
- Organizer
  細胞・組織・臓器工学とオルガノイドワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-22K19456
[Presentation] Micropapillary carcinomaの極性転換不全を標的とした治療戦略2023
- Author(s)
  小沼邦重
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K07395
[Presentation] Micropapillary carcinoma病態における極性転換不全とその分子機構2022
- Author(s)
  小沼邦重、井上正宏
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08286
[Presentation] オルガノイドを用いたがん細胞塊によるがん気道内転移モデル2022
- Author(s)
  松浦吉晃, 小沼邦重, 下村雅律, 内堀篤樹, 井上匡美, 井上正宏
- Organizer
  第75回胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-22K19456
[Presentation] オルガノイドを用いたがん気道内転移モデルによるSTASの病態検証2022
- Author(s)
  松浦吉晃, 小沼邦重, 下村雅律, 内堀篤樹, 井上匡美, 井上正宏
- Organizer
  第63回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19456
[Presentation] 大腸前がん病変におけるスフェロイド増殖能の多様性2022
- Author(s)
  角南智彦, 井上正宏, 小沼邦重, 山田敦, 武藤学
- Organizer
  第31回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-22K19456
[Presentation] 機能的な単一細胞解析による大腸癌内の相互転換可能な細胞亜集団の解明2022
- Author(s)
  Coppo Roberto, 小沼邦重, 近藤純平, 井上正宏
- Organizer
  第31回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-22K19456
[Presentation] 大腸がん転移におけるがん細胞集団の極性転換の役割2022
- Author(s)
  小沼邦重, 井上正宏
- Organizer
  第31回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-22K19456
[Presentation] Luminal型乳がん由来オルガノイドの培養によるER発現低下メカニズムの解明.2022
- Author(s)
  上松弘幸, 小沼邦重, 杉江知治, 井上正宏
- Organizer
  日本患者由来がんモデル学会学術集会2022
- Data Source
  KAKENHI-PROJECT-22K19456
[Presentation] 機能的な単一細胞解析による大腸癌内の相互転換可能な細胞亜集団の解明2022
- Author(s)
  Roberto Coppo, 近藤純平, 小沼邦重, 井上正宏
- Organizer
  第81回日本癌学会学術総会.
- Data Source
  KAKENHI-PROJECT-22K19456
[Presentation] ER陽性乳がんオルガノイドにおけるin vitroでの継代によるER発現の減弱.2022
- Author(s)
  上松弘幸, 小沼邦重, 杉江知治, 井上正宏
- Organizer
  第81回日本癌学会学術総会.
- Data Source
  KAKENHI-PROJECT-22K19456
[Presentation] 大腸がん細胞集団における薬剤耐性分画の代謝状態の解析2022
- Author(s)
  小沼邦重, 井上正宏
- Organizer
  第18回がんとハイポキシア研究会
- Data Source
  KAKENHI-PROJECT-22K19456
[Presentation] オルガノイドを用いたがん細胞塊によるがん気道内転移モデル2022
- Author(s)
  松浦吉晃, 小沼邦重, 井上匡美, 井上正宏
- Organizer
  第31回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-22K19456
[Presentation] 子宮頸部神経内分泌腫瘍の混合腫瘍におけるクローン起源と分化系列の可塑的な決定2022
- Author(s)
  益田真志, 小沼邦重, 井上正宏
- Organizer
  第81回日本癌学会学術総会.
- Data Source
  KAKENHI-PROJECT-22K19456
[Presentation] Micropapillary carcinoma病態における極性転換不全とその分子機構2022
- Author(s)
  小沼邦重, 井上正宏.
- Organizer
  第81回日本癌学会学術総会.
- Data Source
  KAKENHI-PROJECT-22K19456
[Presentation] 大腸がん転移におけるがん細胞集団の極性転換の役割2022
- Author(s)
  小沼邦重、井上正宏
- Organizer
  日本がん転移学会
- Data Source
  KAKENHI-PROJECT-20K08286
[Presentation] 光線力学療法アップコンバージョン法による細胞毒性2021
- Author(s)
  小滝咲、江田明優、小村勇人、Loghapriya Sivasamy、粳間由幸、小沼邦重
- Organizer
  第27回　高専シンポジウム
- Data Source
  KAKENHI-PROJECT-19K12813
[Presentation] 大腸がん転移におけるがん細胞集団の極性転換の役割2021
- Author(s)
  小沼邦重、近藤純平、井上正宏
- Organizer
  第30回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-20K08286
[Presentation] 大腸がん転移におけるがん細胞集団の極性転換の役割2021
- Author(s)
  小沼邦重、井上正宏
- Organizer
  患者由来がんモデル研究会2021
- Data Source
  KAKENHI-PROJECT-20K08286
[Presentation] 大腸がん転移におけるがん細胞集団の極性転換の役割2021
- Author(s)
  小沼邦重、近藤純平、井上正宏
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08286
[Presentation] Micropapillary carcinoma病態における極性転換とその分子機構2020
- Author(s)
  1.小沼邦重、近藤純平、井上正宏
- Organizer
  患者由来がんモデル講演会
- Data Source
  KAKENHI-PROJECT-20K08286
[Presentation] 大腸がん転移におけるがん細胞集団の極性転換の役割2020
- Author(s)
  小沼邦重、近藤純平、井上正宏
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08286
[Presentation] 糖含有次世代型光増感剤の開発・研究2020
- Author(s)
  遠藤聖也、坂本啓太、加藤有紀、小沼邦重、岡田太、 Ping-Shan Lai，粳間由幸
- Organizer
  日本化学会第101回春季年会
- Data Source
  KAKENHI-PROJECT-19K12813
[Presentation] 二世代型光増感剤の合成と物性評価2020
- Author(s)
  原望実，坂本啓太，加藤有紀、小沼邦重、岡田太、Ping-Shan Lai，粳間由幸
- Organizer
  日本化学会第101回春季年会
- Data Source
  KAKENHI-PROJECT-19K12813
[Presentation] 新規合成ルートを用いた光増感剤の合成と生物学的評価2020
- Author(s)
  江田明優、坂本啓太、加藤有紀、小沼邦重、岡田太、 Ping-Shan Lai、粳間由幸
- Organizer
  日本化学会第101回春季年会
- Data Source
  KAKENHI-PROJECT-19K12813
[Presentation] 炎症発癌の遮断に向けた化合物の実効性の検証2013
- Author(s)
  小沼邦重、池田多津世、末永裕佳、神田裕介、藤井順逸、小林正伸、尾﨑充彦、岡田太
- Organizer
  第66回日本酸化ストレス学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2013-06-13
- Data Source
  KAKENHI-PROJECT-24700959
[Presentation] 発癌要因としての低酸素再酸素化由来の活性酸素・活性窒素2013
- Author(s)
  神田裕介、坂木隆太、小沼邦重、浜田淳一、小林正伸、尾﨑充彦、井藤久雄、岡田　太
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24700959
[Presentation] 発癌要因としての低酸素再酸素化由来の活性酸素・活性窒素(Hypoxia-reoxygeneration and its-derived reactive nitrogen oxides as a carcinogenic factor)2013
- Author(s)
  神田裕介、坂木隆太、小沼邦重、浜田淳一、小林正伸、尾﨑充彦、井藤久雄、岡田太
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2013-10-05
- Data Source
  KAKENHI-PROJECT-24700959
[Presentation] in vitro腸発がん再構成系における炎症の発がん促進作用文部科学省科学研究費補助金新学術領域研究「がん研究等の特性を踏まえた支援活動」2013
- Author(s)
  小沼邦重、落合雅子、今井俊夫、岡本康司、中釜斉、筆宝義隆
- Organizer
  平成23年度「個体レベルでのがん研究支援活動ワークショップ」
- Place of Presentation
  大津
- Year and Date
  2013-01-18
- Data Source
  KAKENHI-PROJECT-24700959
[Presentation] 発癌要因としての低酸素再酸素化と活性酸化窒素の役割2013
- Author(s)
  神田裕介、坂木隆太、小沼邦重、浜田淳一、小林正伸、尾﨑充彦、岡田太
- Organizer
  第13回日本NO学会学術総会
- Place of Presentation
  沖縄県医師会館(南風原町)
- Year and Date
  2013-06-28
- Data Source
  KAKENHI-PROJECT-24700959
[Presentation] ヒト骨肉腫の肺転移にはmiR-143標的遺伝子であるPAI-1およびMMP13が関与する2013
- Author(s)
  平畑美緒、伊藤真保、神田裕介、小沼邦重、岡田太、尾﨑充彦
- Organizer
  第5回日本RNAi研究会
- Place of Presentation
  広島市
- Year and Date
  2013-08-30
- Data Source
  KAKENHI-PROJECT-24700959
[Presentation] Characterization of Tumors Generated by Lentivirus-based Direct Transformation of Primary Murine Intestinal Cells2012
- Author(s)
  小沼邦重、筆宝義隆、落合雅子、中釜斉
- Organizer
  第71 回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌、札幌市教育文化会館、さっぽろ芸文館、札幌市民ホール (北海道札幌市)
- Data Source
  KAKENHI-PROJECT-24700959
[Presentation] miR-143の標的であるPAI-1は骨肉腫細胞の肺転移に関与する
- Author(s)
  平畑美緒，伊藤真保，神田裕介，小沼邦重，押村光雄，岡田　太，尾﨑充彦
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島国際会議場（広島）
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26860264
[Presentation] ヒト大腸腺腫細胞の大腸癌細胞への進展における慢性炎症由来一酸化窒素の証明とfascinの同定
- Author(s)
  神田裕介，河口徳一，田澤　大，平畑美緒，小沼邦重，北川知行，尾﨑充彦，岡田　太
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26860264

1. INOUE Masahiro (10342990)

# of Collaborated Projects: 3 results

# of Collaborated Products: 34 results
2. URUMA YOSHIYUKI (70442457)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. 近藤純平 (80624593)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
4. 青木正博 (60362464)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 田中正太郎 (90380667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KIMURA Toshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. COPPO ROBERTO

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
8. 岡田太

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 上田豊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 松崎慎哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Onuma Kunishige 小沼 邦重

Kunishige Onuma 小沼 邦重

ONUMA Kunishige 小沼 邦重

Research Projects

Research Products

Co-Researchers

Establishment of photodynamic therapy for deep cell tumors using the up-conversion method

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新しい細胞集塊薬剤浸透性評価モデルの開発

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Micropapillary carcinomaの極性転換を標的とした治療戦略Principal Investigator

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Mechanisms of the immune evasion through polarity switching of the colorectal cancer clusters

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The mechanism of polarity switching in the cluster of human colorectal adenocarcinoma during the process of metastasisPrincipal Investigator

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Development of Deep Cellular Cancer Therapy Using Photosensitizer-Encapsulated Upconversion Particles

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Studies on inflammation-induced intestinal bowel carcinogenesis by using organoidsPrincipal Investigator

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Mechanism of inflammation-accelerate colorectal carcinogenesis by reconstitutive modelPrincipal Investigator

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[Journal Article] Clonal Origin and Lineage Ambiguity in Mixed Neuroendocrine Carcinoma of the Uterine Cervix2024

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[Journal Article] Oxygen metabolism analysis of a single organoid for non-invasive discrimination of cancer subpopulations with different growth capabilities2023

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[Journal Article] Inhibition of the bone morphogenetic protein pathway suppresses tumor growth through downregulation of epidermal growth factor receptor in <scp>MEK</scp>/<scp>ERK</scp>‐dependent colorectal cancer2023

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[Journal Article] Electrochemical sensing of oxygen metabolism for a three-dimensional cultured model with biomimetic vascular flow2023

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[Journal Article] Tracking the growth fate of single cells and isolating slow-growing cells in human colorectal cancer organoids2023

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[Journal Article] Distinct but interchangeable subpopulations of colorectal cancer cells with different growth fates and drug sensitivity2023

Onuma Kunishige 小沼邦重

Kunishige Onuma 小沼邦重

ONUMA Kunishige 小沼邦重

[Presentation] 大腸癌de novo　クラスターが示す細胞運命のNotchシグナルによる制御2023