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Sone Masamitsu  曽根 正光

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SONE Masamitsu  曽根 正光

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Researcher Number 90599771
Other IDs
Affiliation (Current) 2025: 北海道大学, 低温科学研究所, 助教
Affiliation (based on the past Project Information) *help 2019 – 2024: 北海道大学, 低温科学研究所, 助教
2017 – 2020: 千葉大学, 大学院医学研究院, 特任助教
2015: 京都大学, iPS細胞研究所, 特定研究員
2014 – 2015: 京都大学, iPS細胞研究所, 研究員
2012: 京都大学, iPS 細胞研究所, 研究員
2012: 京都大学, iPS細胞研究所, 研究員
2011: 京都大学, iPS細胞研究所, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 48040:Medical biochemistry-related / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Tumor biology / Genome biology / General medical chemistry
Except Principal Investigator
Basic Section 55060:Emergency medicine-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 56020:Orthopedics-related
Keywords
Principal Investigator
iPS細胞 / 冬眠 / 多能性幹細胞 / クロマチン高次構造 / 低温耐性 / 季節 / ハムスター / 季節適応 / シリアンハムスター / エピジェネティクス … More / シングルセルRNA-seq / RNA-seq / 巨核球 / シングルセル / 血小板 / HIF / 解糖系代謝 / 発がん / 分化 / 3C / 転写制御 / エンハンサートラップ / エンハンサー / Hi-C / クロマチン構造 / bivalent ヒストンH3 / bivalentヒストンH3 / 3C-Seq / 次世代シーケンサー / iPS 細胞 / ヒストン修飾 … More
Except Principal Investigator
血小板 / 骨癒合 / 冬眠 / 凝固異常 / 低体温症 / HLA / 骨折治療 / iPS細胞 / 人工血小板 / 再生医療 / 多血小板血漿 / iPS細胞由来人工巨核球・血小板凍結乾燥製剤 / 骨形成促進 / サイトカイン / 骨癒合促進 / iPS細胞由来血小板 Less
  • Research Projects

    (9 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (11 People)
  •  環境変動に対する冬眠哺乳類細胞のストレス耐性メカニズムの解明Principal Investigator

    • Principal Investigator
      曽根 正光
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Hokkaido University
  •  冬眠動物がもつ体温変化に応じた血栓回避の抗凝固メカニズム解明と新規抗凝固薬の開発

    • Principal Investigator
      高氏 修平
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Hokkaido University
  •  Epigenetic mechanisms underlying seasonal body remodeling of a mammalian hibernatorPrincipal Investigator

    • Principal Investigator
      Sone Masamitsu
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
    • Research Institution
      Hokkaido University
  •  Single cell analysis of maturating megakaryocytic cell line to enhance the platelet productivity for industrializationPrincipal Investigator

    • Principal Investigator
      Sone Masamitsu
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Hokkaido University
  •  Development of iPS cell-derived platelet preparation with bone fusion promoting effect

    • Principal Investigator
      Shiga Yasuhiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Chiba University
  •  Development of bone adhesive treatment with functionally modified platelets

    • Principal Investigator
      Eto Koji
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Chiba University
  •  Uncovering the mechanisms of glycolytic activation in tumorigenesis using iPS derivation as a model systemPrincipal Investigator

    • Principal Investigator
      Sone Masamitsu
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor biology
    • Research Institution
      Chiba University
  •  Genome-wide analysis of gene expression regulated by three dimensional chromatin structurePrincipal Investigator

    • Principal Investigator
      Sone Masamitsu
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Genome biology
    • Research Institution
      Kyoto University
  •  Analysis of Histon modification and higher-order structure that regulate pluripotency of iPS cellsPrincipal Investigator

    • Principal Investigator
      SONE Masamitsu
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University

All 2024 2023 2021 2020 2012 2011

All Journal Article Presentation

  • [Journal Article] Slow decrease in temperature produces readthrough transcripts in mammalian hibernation2024

    • Author(s)
      Sone Masamitsu、Yamashita Junpei、Shigenobu Shuji、Yamaguchi Yoshifumi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 709 Pages: 149837-149837

    • DOI

      10.1016/j.bbrc.2024.149837

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K19320, KAKENHI-ORGANIZER-23H04939, KAKENHI-PLANNED-23H04940, KAKENHI-PROJECT-23K28012
  • [Journal Article] How do cells of mammalian hibernators cope with cold stress?2023

    • Author(s)
      曽根正光、山口良文
    • Journal Title

      低温科学

      Volume: 81 Pages: 159-172

    • DOI

      10.14943/lowtemsci.81.159

    • ISSN
      1880-7593
    • Year and Date
      2023-03-20
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-20H05766, KAKENHI-PROJECT-22K19320
  • [Journal Article] The Effect of Megakaryocytes and Platelets Derived from Human Induced Pluripotent Stem Cells on Bone Formation2021

    • Author(s)
      Masashi Sato、Yasuhiro Shiga、Naoya Takayama、Masamitsu Sone、Kentaro Kosaka、Itsuro Motegi、Norichika Mizuki、Kazuhide Inage、Yawara Eguchi、Miyako Narita、Sumihisa Orita、Koji Eto、Seiji Ohtori
    • Journal Title

      Spine Surgery and Related Research

      Volume: _

    • NAID

      130008044530

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K22675
  • [Journal Article] The Effect of Megakaryocytes and Platelets Derived from Human-Induced Pluripotent Stem Cells on Bone Formation2021

    • Author(s)
      Masashi Sato, Yasuhiro Shiga, Naoya Takayama, Masamitsu Sone, Kentaro Kosaka, Itsuro Motegi, Norichika Mizuki, Kazuhide Inage, Yawara Eguchi, Miyako Narita, Sumihisa Orita, Koji Eto, Seiji Ohtori
    • Journal Title

      Spine Surgery and Related Research

      Volume: 5 Issue: 3 Pages: 196-204

    • DOI

      10.22603/ssrr.2020-0226

    • NAID

      130008044530

    • ISSN
      2432-261X
    • Year and Date
      2021-05-27
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09615, KAKENHI-PROJECT-18H04164
  • [Presentation] 冬眠哺乳類細胞の低温誘導性フェロトーシス回避メカニズム2024

    • Author(s)
      曽根 正光
    • Organizer
      レドックスR&D戦略委員会 第4回 春のシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K19320
  • [Presentation] Gpx4-dependent resistance against cold-induced ferroptosis in a mammalian hibernator, Syrian hamster2023

    • Author(s)
      Masamitsu Sone, Yoshifumi Yamaguchi
    • Organizer
      Japan Australia Meeting on Cell Death 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19320
  • [Presentation] Gpx4依存的なシリアンハムスターの低温細胞死回避メカニズム2023

    • Author(s)
      曽根 正光,三橋 ののか,岡橋 良仁,山口 良文
    • Organizer
      第5回冬眠休眠研究会
    • Data Source
      KAKENHI-PROJECT-22K19320
  • [Presentation] 不死化巨核球による血小板産生過程のマルチオミクス解析2020

    • Author(s)
      曽根 正光
    • Organizer
      第6回北大部局横断シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07344
  • [Presentation] GLOBAL ANALYSIS OF HIGHER-ORDER CHROMATIN STRUCTURE IN PLURIPOTENT STEM CELLS2012

    • Author(s)
      池田宏輝、曽根正光、山中伸弥、山本拓也
    • Organizer
      International Society of Stem Cell Research 10th Annual Meeting
    • Place of Presentation
      横浜
    • Year and Date
      2012-06-14
    • Data Source
      KAKENHI-PROJECT-23790329
  • [Presentation] INFERING THE TRANSCRIPTION NETWORKS REQUIRED FOR INDUCTION OF PLURIPOTECY2012

    • Author(s)
      曽根 正光
    • Organizer
      International Society for Stem Cell Research 10th Annual Meeting
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23790329
  • [Presentation] 体細胞リプログラミングにおける転写ネットワーク変遷の数理解析2012

    • Author(s)
      曽根 正光
    • Organizer
      定量生物学の会 第五回年会
    • Place of Presentation
      東京大学生産技術研究所
    • Data Source
      KAKENHI-PROJECT-23790329
  • [Presentation] 体細胞リプログラミング初期における遺伝子発現解析2012

    • Author(s)
      曽根 正光
    • Organizer
      第4回 定量生物学の会年会
    • Place of Presentation
      名古屋大学野依記念学術交流館
    • Data Source
      KAKENHI-PROJECT-23790329
  • [Presentation] Analysis of Chromosome Conformation in Induced Pluripotent Stem Cells by 3C Method2011

    • Author(s)
      池田宏輝、曽根正光、山中伸弥、山本拓也
    • Organizer
      第63回日本細胞生物学会大会
    • Place of Presentation
      北海道
    • Year and Date
      2011-06-15
    • Data Source
      KAKENHI-PROJECT-23790329
  • [Presentation] Hi-C Seq を用いた iPS 細胞における染色体高次構造の決定2011

    • Author(s)
      池田宏輝、曽根正光、山中伸弥、山本拓也
    • Organizer
      NGS 現場の会:第1回研究会
    • Place of Presentation
      静岡
    • Year and Date
      2011-05-28
    • Data Source
      KAKENHI-PROJECT-23790329
  • [Presentation] Genome wide analysis of chromosome conformation in pluripotent stem cells by Hi-C2011

    • Author(s)
      池田宏輝、曽根正光、山中伸弥、山本拓也
    • Organizer
      第34回 日本分子生物学会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-13
    • Data Source
      KAKENHI-PROJECT-23790329
  • [Presentation] Screening for the earliest determinant factors in iPS cell derivation2011

    • Author(s)
      曽根 正光
    • Organizer
      第34回 日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23790329
  • 1.  Shiga Yasuhiro (90568669)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  大鳥 精司 (40361430)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  折田 純久 (60638310)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  Eto Koji (50286986)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  高山 直也 (10584229)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  稲毛 一秀 (80793629)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  山口 良文 (10447443)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  高氏 修平 (20793897)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  早川 峰司 (10374282)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  IKEDA Hiroki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 11.  KABATA Mio
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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