Baba Takashi 馬場崇

Researcher Number	90609992
Other IDs
Affiliation (Current)	2026: 和歌山県立医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2020 – 2025: 和歌山県立医科大学, 医学部, 講師 2019: 秋田大学, 医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 44010:Cell biology-related / 0701:Biology at molecular to cellular levels, and related fields
Keywords	Principal Investigator 乳酸 / IL-23 / マクロファージ / 小胞輸送 / イノシトールリン脂質 / 腫瘍内微小環境 / がん微小環境 / 腫瘍内高乳酸環境 / Il23a / オルガネラ … More / 分泌経路 / 高乳酸環境 / ER exit site / 小胞体出芽部位 / 細胞内小胞輸送 / 細胞膜 / 後期エンドソーム・リソソーム / エンドサイトーシス / エンドソーム / BRET Less

Research Projects
(4 results)
Research Products
(9 results)

Understanding the mechanisms underlying the regulation of gene expression in macrophages under conditions of elevated lactic acidPrincipal Investigator
- Principal Investigator
  
  馬場崇
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Wakayama Medical University
腫瘍随伴マクロファージの多様な乳酸シグナルネットワークの解明Principal Investigator
- Principal Investigator
  
  馬場崇
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Wakayama Medical University
Involvement of the localization of ER exit site in secretory functionPrincipal Investigator
- Principal Investigator
  
  Baba Takashi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Wakayama Medical University
Comprehensive analysis of roles of phosphoinositides in intracellular vesicular traffickingPrincipal Investigator
- Principal Investigator
  
  Baba Takashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0701:Biology at molecular to cellular levels, and related fields
- Research Institution
  Wakayama Medical University
  Akita University

All 2024 2023 2020 2019

All Journal Article Presentation

[Journal Article] Tumor‐derived lactic acid promotes acetylation of histone H3K27 and differentiation of IL‐10‐producing regulatory B cells through direct and indirect signaling pathways2024
- Author(s)
  Muraoka Satoshi*、Baba Takashi*、Akazawa Takashi、Katayama Kei‐ichi、Kusumoto Hiroki、Yamashita Shimpei、Kohjimoto Yasuo、Iwabuchi Sadahiro、Hashimoto Shinichi、Hara Isao、Inoue Norimitsu
- Journal Title
  
  International Journal of Cancer
  
  Volume: 156 Issue: 4 Pages: 840-852
- DOI
  10.1002/ijc.35229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07155, KAKENHI-PROJECT-24K12444
[Journal Article] Myelination of peripheral nerves is controlled by PI4KB through regulation of Schwann cell Golgi function2020
- Author(s)
  Baba Takashi、Alvarez-Prats Alejandro、Kim Yeun Ju、Abebe Daniel、Wilson Steve、Aldworth Zane、Stopfer Mark A.、Heuser John、Balla Tamas
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 117 Issue: 45 Pages: 28102-28113
- DOI
  10.1073/pnas.2007432117
- Data Source
  KAKENHI-PROJECT-19K23712
[Journal Article] DDHD1, but Not DDHD2, Suppresses Neurite Outgrowth in SH-SY5Y and PC12 Cells by Regulating Protein Transport From Recycling Endosomes.2020
- Author(s)
  Maemoto Y, Maruyama T, Nemoto K, Baba T, Motohashi M, Ito A, Tagaya M, Tani K.
- Journal Title
  
  Front Cell Dev Biol.
  
  Volume: 23 Pages: 1-12
- DOI
  10.3389/fcell.2020.00670
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15787
[Journal Article] Emerging roles of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate as regulators of multiple steps in autophagy2020
- Author(s)
  Baba Takashi、Balla Tamas
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 168 Issue: 4 Pages: 329-336
- DOI
  10.1093/jb/mvaa089
- Data Source
  KAKENHI-PROJECT-19K23712
[Presentation] Tumor-derived lactic acid promotes acetylation of histone H3K27 and differentiation of IL-10-producing regulatory B cells through direct and indirect signaling pathways.2024
- Author(s)
  Satoshi Muraoka, Takashi Baba, Akazawa Takashi, Katayama Ken-ichi, Kusumoto Hiroki, Yamashita Shimpei, Kohjimoto Yasuo, Iwabuchi Sadahiro, Hashimoto Shinichi, Hara Isao and Norimitsu Inoue
- Organizer
  第83回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07155
[Presentation] 腫瘍内高乳酸環境によるB細胞のヒストンH3アセチル化とIL-10産生の増強2024
- Author(s)
  村岡聡、馬場崇、赤澤隆、片山圭一、楠本浩貴、山下真平、柑本康夫、岩淵禎弘、橋本真一、原勲、井上徳光
- Organizer
  第52回和歌山悪性腫瘍研究会
- Data Source
  KAKENHI-PROJECT-22K07155
[Presentation] Screening of genes required for CD73 induced by tumor-derived lactic acid2023
- Author(s)
  Ying Hongwu, Takashi Baba, Norimitsu Inoue
- Organizer
  第51回和歌山悪性腫瘍研究会
- Data Source
  KAKENHI-PROJECT-22K07155
[Presentation] 腫瘍内高乳酸環境によるマクロファージのIl23a転写制御機構の解明2023
- Author(s)
  馬場崇、遊佐宏介、井上徳光
- Organizer
  第27回がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-22K07155
[Presentation] 後期エンドソームにおけるPI(4,5)P2は低分子量GTPaseであるRab7を制御する。2019
- Author(s)
  馬場崇、Toth, DJ., Sengpta, N., Kim, YJ., Balla, T.
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K23712

Baba Takashi 馬場 崇

Research Projects

Research Products

Understanding the mechanisms underlying the regulation of gene expression in macrophages under conditions of elevated lactic acidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腫瘍随伴マクロファージの多様な乳酸シグナルネットワークの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Involvement of the localization of ER exit site in secretory functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive analysis of roles of phosphoinositides in intracellular vesicular traffickingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Tumor‐derived lactic acid promotes acetylation of histone H3K27 and differentiation of IL‐10‐producing regulatory B cells through direct and indirect signaling pathways2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Myelination of peripheral nerves is controlled by PI4KB through regulation of Schwann cell Golgi function2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DDHD1, but Not DDHD2, Suppresses Neurite Outgrowth in SH-SY5Y and PC12 Cells by Regulating Protein Transport From Recycling Endosomes.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Emerging roles of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate as regulators of multiple steps in autophagy2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Tumor-derived lactic acid promotes acetylation of histone H3K27 and differentiation of IL-10-producing regulatory B cells through direct and indirect signaling pathways.2024

Author(s)

Organizer

Data Source

[Presentation] 腫瘍内高乳酸環境によるB細胞のヒストンH3アセチル化とIL-10産生の増強2024

Author(s)

Organizer

Data Source

[Presentation] Screening of genes required for CD73 induced by tumor-derived lactic acid2023

Author(s)

Organizer

Data Source

[Presentation] 腫瘍内高乳酸環境によるマクロファージのIl23a転写制御機構の解明2023

Author(s)

Organizer

Data Source

[Presentation] 後期エンドソームにおけるPI(4,5)P2は低分子量GTPaseであるRab7を制御する。2019

Author(s)

Organizer

Data Source

Baba Takashi 馬場崇